Lab Soft News had a recent reference to an article on reflux disease, Barrett's esophagus, long considered a pre-neoplastic condition and actual observed rates of carcinoma in Barrett's esophagus.  

Many GI pathologists, including myself will tell you "we see a ton of Barrett's" but few adenocarcinomas. Esophagectomies are vanishly rare. Very uncommon specimen so from my own personal experience I think these numbers are accurate.  For better or for worse this could result in fewer "screening" biopsies...

Will see if endoscopists endorse...