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Pure Nootropics | Smart Drugs to Enhance Your Life

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Here are some selected posts from our knowledgebase/blog. These posts are a good starting point for those new to cognitive enhancement or those that simply dont know where to start.

A brief introduction to cognitive enhancement supplements, also known as Nootropics

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Pure Nootropics | Smart Drugs to Enhance Your Life

Nootropic – Wikipedia

Nootropics ( noh–TROP-iks) (colloquial: smart drugs and cognitive enhancers) are drugs, supplements, and other substances that may improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.[1] While many substances are purported to improve cognition, research is at a preliminary stage as of 2018, and the effects of the majority of these agents are not fully determined.

The use of cognition-enhancing drugs by healthy individuals in the absence of a medical indication spans numerous controversial issues, including the ethics and fairness of their use, concerns over adverse effects, and the diversion of prescription drugs for nonmedical uses, among others.[1][2] Nonetheless, the international sales of cognition-enhancing supplements exceeded US$1 billion in 2015 when global demand for these compounds grew.[3]

The word nootropic was coined in 1972 by a Romanian psychologist and chemist, Corneliu E. Giurgea,[4][5] from the Greek words (nous), or “mind”, and (trepein), meaning to bend or turn.[6]

In 2008, the most commonly used class of drug was stimulants, such as caffeine.[7] Manufacturer’s marketing claims for dietary supplements are usually not formally tested and verified by independent entities.[8]

The use of prescription stimulants is especially prevalent among students.[9] Surveys suggest that 0.74.5% of German students have used cognitive enhancers in their lifetime.[10][11][12] Stimulants such as dimethylamylamine and methylphenidate are used on college campuses and by younger groups.[13] Based upon studies of self-reported illicit stimulant use, 535% of college students use diverted ADHD stimulants, which are primarily intended for performance enhancement rather than as recreational drugs.[14][15][16] Several factors positively and negatively influence an individual’s willingness to use a drug for the purpose of enhancing cognitive performance. Among them are personal characteristics, drug characteristics, and characteristics of the social context.[10][11][17][18]

The main concern with pharmaceutical drugs is adverse effects, which also apply to nootropics with undefined effects. Long-term safety evidence is typically unavailable for nootropics.[13] Racetams piracetam and other compounds that are structurally related to piracetam have few serious adverse effects and low toxicity, but there is little evidence that they enhance cognition in people having no cognitive impairments.[19]

In the United States, dietary supplements may be marketed if the manufacturer can show that the supplement is generally recognized as safe, and if the manufacturer does not make any claims about using the supplement to treat or prevent any disease or condition; supplements that contain drugs or advertise health claims are illegal under US law.[20]

Systematic reviews and meta-analyses of clinical human research using low doses of certain central nervous system stimulants found enhanced cognition in healthy people.[21][22][23] In particular, the classes of stimulants that demonstrate cognition-enhancing effects in humans act as direct agonists or indirect agonists of dopamine receptor D1, adrenoceptor A2, or both types of receptor in the prefrontal cortex.[21][22][24][25] Relatively high doses of stimulants cause cognitive deficits.[24][25]

Racetams, such as piracetam, oxiracetam, and aniracetam, which are often marketed as cognitive enhancers and sold over-the-counter. Racetams are often referred to as nootropics, but this property is not well established.[31] The racetams have poorly understood mechanisms, although piracetam and aniracetam are known to act as positive allosteric modulators of AMPA receptors and appear to modulate cholinergic systems.[32]

According to the US Food and Drug Administration, “Piracetam is not a vitamin, mineral, amino acid, herb or other botanical, or dietary substance for use by man to supplement the diet by increasing the total dietary intake. Further, piracetam is not a concentrate, metabolite, constituent, extract or combination of any such dietary ingredient. […] Accordingly, these products are drugs, under section 201(g)(1)(C) of the Act, 21 U.S.C. 321(g)(1)(C), because they are not foods and they are intended to affect the structure or any function of the body. Moreover, these products are new drugs as defined by section 201(p) of the Act, 21 U.S.C. 321(p), because they are not generally recognized as safe and effective for use under the conditions prescribed, recommended, or suggested in their labeling.”[33]

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Nootropic – Wikipedia

Nootropics.com | The Best Nootropics For Beginners & Experts

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Nootropics.com | The Best Nootropics For Beginners & Experts

Buy The Best Nootropics Online Today at Nootropics Depot

Nootropics Depot features an extensive range of dietary supplements and nootropic compounds. Nootropics Depot offers the best nootropics and natural extracts from industry leading manufacturers including Nammex, Verdure Sciences, Embria Health Science, and Ixoreal Biomed.

We provide a variety of dietary supplements and nootropic compounds in both capsule and powder forms, allowing you to develop the best nootropic stack.

From common cholinergics to whole fruiting body medicinal mushroom extracts and fish oil supplements, Nootropics Depot provides a wide range of dietary supplements and nootropic compounds. Sort our product selection by use such as nootropics, amino acid supplements, mushroom extract supplements, or increasingly popular ayurvedic supplements.

When you buy from Nootropics Depot, you can trust that you are getting a quality product that has undergone extensive testing for both purity and identity. Nootropics Depot routinely conducts in-house and third-party lab testing to ensure product authenticity and efficacy.

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See the latest updates to our nootropics blog below to begin exploring the vast world of nootropics and dietary supplements.

Two Forms OfMagnesium Supplements With Two Different

What is Cognizin Citicoline?Not every form of choline readily makes it into

What Is 7,8-Dihydroxyflavone?7,8-Dihydroxyflavone, also known as 7,8-DHF,

COMPARING RHODIOLA ROSEA EXTRACTS: ROSAVINS VS. SALIDROSIDERhodiola rosea, more commonly known as golden root or rose root…

BERBERINE: A LOOK AT THE POTENTIAL BENEFITS OF THIS VERSATILE SUPPLEMENTBerberine is a bright yellow alkaloid that is found in a variety of plants…

HERICIUM ERINACEUS: WHICH IS THE BEST LION’S MANE MUSHROOM FOR YOU?Hericium erinaceus, also known as lions mane mushroom…

NITRIC OXIDE SUPPLEMENTS REVIEWED: L-CITRULLINE, AGMATINE AND AAKGNitric oxide is a very interesting neurotransmitter within the body…

GANODERMA LUCIDUM: WHICH IS THE BEST RED REISHI MUSHROOM FOR YOU?We are often asked which Red Reishi extract is best…

COMPREHENSIVE GUIDE TO THE BEST ANTI-AGING SUPPLEMENTSLet’s facilitate a healthy aging process, rather than trying to completely halt it…

WHICH IS THE BEST CORDYCEPS MUSHROOM FOR YOU?Did you know not all Cordyceps mushroom extracts are made the same way?

BACOPA MONNIERI: BACOGNIZE VS. SYNAPSA – WHICH AYURVEDIC HERB IS RIGHT FOR YOU?Commonly known as the waterhyssop or brahmi…

THE NOOTROPIC SYNERGY OF CAFFEINE AND L-THEANINEOne of the most popular natural nootropic stacks is a simple combination of L-theanine and caffeine…

L-CITRULLINE VS. L-CITRULLINE DL-MALATE: WHICH IS BEST?L-citrulline is one of three dietary amino acids involved in the urea cycle…

SHILAJIT: A LOOK AT THIS AMAZING AYURVEDIC SUPPLEMENTShilajit is a sticky, tar-like substance often appearing dark brown in color…

ULTIMATE GUIDE TO CHOLINE SUPPLEMENTSCholine is an essential nutrient that is found in a variety of foods…

ULTIMATE GUIDE TO KRILL AND FISH OIL SUPPLEMENTSFish oil supplements are going to provide a very solid base to build a nootropics stack upon…

WHAT YOU MIGHT NOT KNOW ABOUT PANAX GINSENG SUPPLEMENTSGinseng is one of the most well known herbs in the world…

Continued here:

Buy The Best Nootropics Online Today at Nootropics Depot

Nootropics r/Nootropics – reddit

So essentially, theres this bill called Stop the Importation and Trafficking of Synthetic Analogues (SITSA) Act. It gives the DEA and the attorney general almost completely unchecked power to schedule any drug they see fit without following the currently established legal criteria to ban certain substances. In Section 2, Subsection 3B of the bill, this is the most worrying part that affects many different nootropics from phenibut to adrafinil or even kratom or tianepetine.

6)Schedule A(A)In generalThe drug or substance

(i)has

(I)a chemical structure that is substantially similar to the chemical structure of a controlled substance in schedule I, II, III, IV, or V; and

(II)an actual or predicted stimulant, depressant, or hallucinogenic effect on the central nervous system that is substantially similar to or greater than the stimulant, depressant, or hallucinogenic effect on the central nervous system of a controlled substance in schedule I, II, III, IV, or V; and

(ii)is not

(I)listed or otherwise included in any other schedule in this section or by regulation of the Attorney General; and

(II)with respect to a particular person, subject to an exemption that is in effect for investigational use, for that person, under section 505 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 355) to the extent conduct with respect to such substance is pursuant to such exemption.

(B)Predicted stimulant, depressant, or hallucinogenic effectFor purpose of this paragraph, a predicted stimulant, depressant, or hallucinogenic effect on the central nervous system may be based on

(i)the chemical structure, structure activity relationships, binding receptor assays, or other relevant scientific information about the substance;

(ii)

(I)the current or relative potential for abuse of the substance; and

(II)the clandestine importation, manufacture, or distribution, or diversion from legitimate channels, of the substance; or

(iii)the capacity of the substance to cause a state of dependence, including physical or psychological dependence that is similar to or greater than that of a controlled substance in schedule I, II, III, IV, or V.

This is concerning due to Phenibut having a similar pharmaceutical effect to Lyrica (schedule V) nd also being able to be (A) abused, and (B) can cause addiction or dependence similar to benzodiazepines or other GABApentinoids.

Adrafinil is an analogue of Modafinil, a schedule IV drug, so its obvious why that could be banned immediately.

Here is the link to the whole bills information, contact your reps, we need to stop this bill.

https://www.govtrack.us/congress/bills/115/hr2851/summary

Edit: theres a letter from Human Rights Watch to Congress concerning this for those interested: https://www.hrw.org/news/2018/06/14/opposition-letter-hr-2851-stop-importation-and-trafficking-synthetic-analogues-sitsa

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Nootropics r/Nootropics – reddit

Nootropics Expert | The Authority on Nootropic Supplements

Hi David,So Im relatively new to Nootropics. I have done extensive reading on your website, but had a specific help question. Below is a brief summary of my medicated world of mental health:

Last year, a psychiatrist diagnosed me with Anxiety induced ADHD. (Which explained a lot of my academic struggles, feelings of self-worth, etc.)

She started out by prescribing me a Sustained Release (generic version of) Wellbutrin. (150mg) This helped considerably with my feelings of fatigue and lethargy, but didnt do very much in terms of motivation/focus/desire to study or get work done. (I am both a teacher and a student) She had also prescribed some sort of non-addictive anti-anxiety medication which made me feel ill (so I discontinued use within just a few days.)

I like to think Im very aware of both my body and my mind Ive practiced yoga for close to ten years now. I try to eat healthfully, and I try to practice self-care as much as possible.

About 7 months ago, though my doctor added Adderall (combination dosage 20mg XR & 20 mg IR) to my regimen p/day. That, and a new hormonal birth control, has really thrown my life off kilter.

At first, Adderall helped with getting all my work done! Staying focused, on-task, memory, etc. But more recently, I have experienced increased irritability and strong fits of anger(paired with a seemingly greater tolerance to Adderall? It seems to last for a shorter time.)

I have been trying to track how these emotional reactions relate to the time of the month, but is increasingly difficult to track the timing of my mood swings. (My partner has also noticed a change in my behavior.)

I try to take breaks from Adderall, but I find it quite difficult with an increased workload as of late. The days I do take breaks, I get by with combination Caffeine/L-Theanine.

Research into Nootropics, though, gives me hope that there is a better solution for my struggles.

What would you recommend? Ive looked at your suggestions for ADHD and Anxiety (separately), I was just wondering if there was something youd suggest based on my current RX. (I would like to taper off of prescription drugs, ideally. Perhaps come summer time, when I experience a true break, I will be able to relax more with a decreased work schedule

My current idea for a stack includes: Vitamin B-complex, L-theanine, L-tyrosine, Magnesium. Perhaps a cycled 5HTP? (for when PMS is nearly debilitating)

Anyways, if youve read this far, I sincerely appreciate it! Thank you in advance for your consideration.

All the best,M.

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Nootropics Expert | The Authority on Nootropic Supplements

Nootropics to Help Support Brain Function | Nootrobox … – HVMN

Nootrobox is a system of four nootropic blends designed to work together, with each component aimed at specific aspects of cognition. In developing Nootrobox, we apply systems engineering methodology towards human performance. We consider energy, focus, memory, sleep, brain and body metabolism as interconnected pieces of one holistic system.

Rise – The daily nootropic that took Silicon Valley by storm. Featured in top business and tech publications such as Wall Street Journal, Bloomberg and Business Insider, its designed to start your morning.

Sprint – Created with a deliberate ratio of caffeine, which, through studies, has been shown to boost energy, alertness, and focus acutely.

Kado-3 – Daily Omega-3 based nootropic stack to aid with improving mood and brain and body metabolism.

Yawn – Non-habit-forming sleep aid developed with a precision dosage of melatonin, which studies show can assist falling asleep faster and improve sleep quality.

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Nootropics to Help Support Brain Function | Nootrobox … – HVMN

Nootroo – The Gold Standard In Nootropics

Synergistic Effects

Researchers studying deficient brains in older populations are constantly working to activate the cholinergic system, as the neurotransmitter acetylcholine is directly implicated in memory. Normally, administering choline alone can increase cholinergic transmission and raise the levels of acetylcholine in the brain.

However, in some older patients, their cholinergic systems are so deteriorated, that they are unable to turn the choline into acetylcholine. The scientists theorized that if they could administer choline, while simultaneously administering a compound that could correct for the critical age-related neuronal deficiencies, it might enable the choline to be properly metabolized.

When they learned that piracetam enables the central nervous system to function more effectively, the researchers decided to run an experiment on aged rats. They administered choline, piracetam, alone as well as the combination of the two.

Both choline and piracetam alone seemed to have a somewhat positive, albeit limited effect. However, when they combined piracetam and choline, the results were considered “profound.” See the dramatic difference the combination makes in the gold bar labeled “C+P” in the accompanying graph.

Our Gold & Silver stacks are based on the principles behind this synergistic combination of ingredients.

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Nootroo – The Gold Standard In Nootropics

Thrive Naturals Super Brain Renew Review | Brain Supplement …

This companys Super Brain Renew was awarded our 2018 Editors Choice Award of distinction for several key reasons. Lets take a closer look as to why it topped our list.

Key Features & Benefits:

INGREDIENTS & EFFECTIVENESSThrive Naturals Super Brain Renew is comprised of 39 different essential vitamins and nutrients. However, the 5 superhero ingredients are DHA Omega 3, Huperzine A, Phosphatidylserine, Bacopin and N-Acetyl L-Tyrosine. These ingredients have been highly studied and shown to help improve cognitive memory recall, improved mental clarity and focus.

Thrive Naturals uses a special high quality,maximum strengthformula, which none of the others we reviewed had. They also use L-Glutamine and DMAE to aid in overall brain function. Of the dozens of brands we reviewed, very few came close to offering a complete formula with the essential supporting ingredients.

Many of the products we reviewed use synthetic ingredients that can cause unwanted side effects. We really liked that Thrive Naturals utilize third-party testing to guarantee quality and results. Every batch of Super Brain Renew is tested by the manufacturer for consistency and quality control to ensure that you receive exactly what you are paying for.

Thrive Naturals ranked at the top of all the categories that matter: ingredients, customer satisfaction, and customer service.

PRODUCT SAFETYWe want our readers to be aware that some brain and memory products we encountered had unnecessary ingredients, like silica, titanium dioxide, and silicon dioxide that act as fillers. While not necessarily dangerous for you, they can have side effects that are unnecessary and that can be avoided by selecting a better formula.

Thrive Naturals keeps their formula clean and pure, which is the foundation of their natural brand. They use the highest quality ingredients in the proportions that have been shown in studies to be effective. The ingredients in Thrive Naturals Super Brain Renew have no known side effects or harmful interactions with other medicines.

As our trusted reader, your safety is out top concern, and that is why we highly recommend Thrive Naturals Super Brain Renew as a reputable nutritional supplements source with verified satisfied customers. Their products are made in cGMP certified and FDA registered labs, which give us a high comfort level.

COSTThis was the factor that sealed the deal for us in selecting Thrive Naturals Super Brain Renew as our #1 pick. We felt that they have a very reasonable price considering they have the essential brain and memory ingredients, outstanding quality ingredients and effectiveness of their product.

We reviewed a lot of products with varying prices and formulations. Thrive Naturals has found a way to bring to their customers a rock solid, pure and potent product at one of the most competitive prices out there. There is just no better value available on the market today. They could easily charge significantly more for such high HCA potency but have decided to pass the savings on to their customers. Kudos to them for keeping their prices reasonable.

It is the cherry on top of our sundae to find that they deliver a high-quality product at a great price and also offer great customer service. They dont push you into a monthly on-going billing scheme, and they give you a no questions asked 1-Year (365 days) to return the product if you are not completely satisfied. A solid company you can trust.

SUMMARYFrom the group of products we tested, there simply is no comparison to Thrive Naturals Super Brain Renew. The product reigned supreme in all categories we evaluated: Effectiveness, Quality, Safety, Price and Customer Satisfaction. If you are serious about improving your memory, focus and clarity and want a product you can count on to get the results, then Thrive Naturals Super Brain Renew is the right one for you.

Feeling sharper and more focusedIve been using Thrive Naturals Super Brain Renew for almost three weeks now and I can already feel the difference. Im feeling sharper and more focused throughout the day. Will update as I progress, so far so good. Janet A.

*Results may vary.*

Got a promotion at workAmazing! I cant believe this is working for me. I have been taking Thrive Naturals Super Brain Renew for 4 months and it has turned my life around. I even got a promotion at work last week. My boss said he felt I have been laser focused lately. I need more Super Brain Renew!!! Victor M.

*Results may vary.*

Able to focus more and feel calmer and relaxedI am a blogger who works from home and a mother of 3. As a writer it is hard to stay focused with the constant todo list running through my mind. I have been taking Thrive Naturals Super Brain Renew for about 6 weeks now and what I have noticed is that I am able to focus more and feel calmer and relaxed. I have also found that I am sleeping better at night and when I wake, I feel more energy. I have had amazing results and would highly recommend this to anyone. Patricia K.

*Results may vary.*

Right at the top of my mindIll admit it, the first time I bought a memory pill online, I was scammed. The brand I had originally bought from had all these weird synthetic ingredients I couldnt even pronounce, and it just didnt work for me. When I saw my cousin at a reunion she was telling me about how much better her memory has been getting. I asked for her secret. When she said she started taking a memory pill, I started laughing. When she told me about the Thrive Naturals brand she was using, I was skeptical. This time I did my research and when I found out they were legit, I ordered a three-month supply. In the past I would forget where I left the keys, what time I had to pick up my kids from sports and just about everything. Now I feel like I am more on top of things. Things I need to remember are right at the top of my mind, unbelievable. Meredith G.

*Results may vary.*

A lot more mental clarityI think Ive read every review there is to read about brain and memory supplements. Every blog, every anti-aging article, every magazine. Ive learned everything there is to learn about the top ingredients for brain and memory. After finally deciding on Thrive Naturals Super Brain Renew, I can tell you they have the best product out there. It actually works! Ive gained a lot more mental clarity, focus and can even energy in the past 5 weeks then I have had in the past 5 years. I just called in and ordered more this morning. Thank you, Thrive Naturals. Chris M.

*Results may vary.*

Dad now remembers the little thingsI have been searching for the right memory pill for my father for a while now. Though he will not admit it, he does not seem to remember things as well as he used to. I wanted to make sure I got him a good product as I care about his health. I did a lot of research and finally settled on Thrive Naturals Super Brain Renew. First off, the product got to me quickly which was great! My Dad was a bit resistant at first to take it. But, it has not been 2 weeks since he has been on Super Brain Renew and he is already reminding me to order him some more! We can all see the difference. My Dad now remembers the little things more and is more focused when we have conversations. This is everything I could have hoped for and more! I am so excited to have found Super Brain Renew. Alicia R.

*Results may vary.*

1. How does it work?As we age we begin to experience memory loss, trouble focusing and sometimes a feeling of brain fog. Thrive Naturals Super Brain Renew contains natural nutrients, also known as nootropics, which help reverse these conditions in a non-addictive and non-stimulating way. The natural ingredients work to improve both the membrane structure of the brain and fight cell-damaging free radicals. The anti-oxidants and anti-inflammatory effects help improve blood flow and oxygen to the brain, improving mental performance, concentration, and alertness.

2. Are memory pills safe to use?

Thrive Naturals Super Brain Renew is a safe all natural supplement. We always recommend that you consult your physician if you feel it may interfere with an existing medical condition. Pregnant and nursing women should not take Super Brain Renew.

3. How much should do I take?Thrive Naturals Super Brain Renew should be taken twice per day, 1 capsule in the morning and 1 at night with a full glass of water.

4. When can I expect to see results?While results will vary depending on the individual, many see results within the first week, and most will find they have more focus and an improved memory by the end of the first month. One of the reasons that Thrive Naturals Super Brain Renew is so popular is that they offer a 1-Year (365 Day) risk-free trial. This way, customers can feel safe and secure in knowing that they can return the product if it is not working for them. The fact that this brand is willing to offer a risk-free trial speaks to both their confidence in how well the product works but also their commitment to superb customer service.

5. Are there any side effects?There are no known side effects of Super Brain Renew. We recommend not taking more than the recommended dosage. People with known medical conditions or who are nursing or pregnant should consult a physician before taking a brain health pill.

6. If I take a few medications, can I still take a brain and memory pill?It is always recommended that you consult your physician if you have any concerns about adding a new supplement to your daily regimen.

7. Is ordering online safe?Yes, at least with our top recommended brands it is. In our review of different brain pill products on the market, we encountered several companies that automatically enroll you in a monthly continuity shipment plan. We thoroughly vetted our top three recommended brands to ensure they do not do this. Our top recommended Thrive Naturals has a rock solid 90-day return policy that will offer customers a no questions asked refund, which we feel very comfortable with.

8. Why should I choose Thrive Naturals Super Brain Renew?Consumer Advisor Online has awarded them our 2018 Editors Choice Top Pick for several reasons. Thrive Naturals has earned its customers loyalty and trust by focusing strictly on quality and research. They closely inspect each of their batches to ensure they are delivering the purest and most potent ingredients. Here are some of the key points as to why we named them our #1 Pick:

In short, Thrive Naturals spares no expense to bring you the finest ingredients, in the right proportions, manufactured using strict guidelines and is also supported by great customer service. That is why we awarded them our Editors Top Pick Award above all the others. It is not every day that we come across a company that has all the right stuff. Thrive Naturals is the one that shines amongst the rest.

We loved Thrive Naturals Super Brain Renew so much that we reached out to them and asked if we could get a special introductory price for our Consumer Advisor Online readers to help them start feeling the benefits of improved memory and focus.

For a very limited time only, Thrive Naturals is giving you up to 49% off PLUS Free Shipping, depending on what option you choose.

Take advantage of this limited time offer to maximize your brain health and stay healthy with the very best memory and focus supplement on the market!

(Limit 1 Package per customer please only order one of the 1, 3, or 6 pack from this page.)

1-Month Supply(1 BOTTLE)

Original Price: $58.95YOUR PRICE:$43.95+ 6.99 Shipping & HandlingSave $15.00 (25%)

3-MONTH SUPPLY(3 BOTTLES)

Original Price: $176.85YOUR PRICE:$118.95($39.65 each)Save $57.90 (33%)

6-MONTH SUPPLY(6 BOTTLES)

Original Price: $353.70YOUR PRICE:$199.95($33.32 each)Save $153.75 (43%)

Thrive Naturals has one of best reputations and guarantees in the industry, and they stand behind it. If you dont experience the results described, Thrive Naturals wants you to return the product for a full refund.

We put Thrive Naturals guarantee to the test during our research and had no problems getting a full refund once the product was returned.

Follow this link:

Thrive Naturals Super Brain Renew Review | Brain Supplement …

Best Nootropics 2018 (Updated) Nootropics Expert

Ask a group of neurohackers which are the best nootropics and youll get a symphony of opinions. But when you drill down to what people are taking every day you start to see a pattern.

Experienced biohackers working on cognitive enhancement find its easier to focus their brain hacking goals into a few well-defined categories. Then look for the best nootropic to address each one. It looks something like this

I have my favorite nootropics after 10-years of trial and error. And chances are that what works for me may work well for you too. The nootropics Im talking about here are part of the stack I use every day.

Youll notice in the categories above that some nootropics work in multiple areas of cognitive enhancement. The obvious benefit is fewer nootropics in a well-rounded stack.

And once you dive into the neuroscience behind each nootropic, youll find synergy on how many of these compounds work together. This extends to smaller doses of each for a bigger benefit.

Brain optimization comes with a lot of experimenting to find what works best. Trying different compounds, keeping a log of what works and how well, and a considerable investment.

Naturally, Im on the lookout for how to save money without cutting corners. So once Ive narrowed my stack choices, the search begins for a quality pre-made nootropic stack that will save me buying individual packs, tubs of powder or capsules.

Fortunately, I found the best pre-made nootropic stack in late 2015 which covered the bulk of the nootropics Id selected for my stack. Its called Mind Lab Pro.

Ill talk more about Mind Lab Pro in a few minutes and how it ties into my brain hacking goals.The company that makes MLP just recently introduced a new line of supplements called Performance Lab. Offering even more options for brain optimization. More on that later as well.

Before I get into detail on how my stack works, here are what many neurohackers consider the best nootropics available today.

For a more detailed dive into how to build the best nootropic stack, check my other posts:

Beginners Guide to Nootropic Stacks

How to Create the Best Nootropic Stack

Here well do a quick review on building a great nootropic stack.

The more we learn about some of nootropics that have been used for thousands of years for cognitive enhancement. The more we realize these natural compounds are often as good as or better than modern prescription medications.

As you gain experience, youll also come to realize that some pre-made nootropic stacks simply dont make sense. Amounts are well below therapeutic doses to expect any reasonable kind of benefit.

And understand that no one is a master at the science and art of nootropics. Dont believe anything I have to say. Find out for yourself if something is true. And change course when you need to if you want to achieve your neurohacking goals.

Next, well take a closer look at each of the nootropics I recommend and use every day.

Each of the nootropics covered below contain links through to a complete and thorough report. When you click through to each individual nootropic supplement review youll find more detail on what it is, why we use it as a nootropic, how it feels, mechanism of action in the brain, side effects, forms available and recommended doses.

Youll also notice in the table above and each nootropic listed below some are marked with an asterisk (*). This means its part of the Mind Lab Pro formula of two capsules per day.

Each of these nootropics are generally regarded as safe and non-toxic at recommended doses. Your mileage may vary. How you respond to each of these compounds depends on a host of variables including:

So please click through to each nootropic and read the side effects, drug interactions and any other notes or warnings. But in general, these are among the safest cognitive enhancers we know of.

Read more about Nootropics Safety and Side Effects

ALCAR helps transport of fatty acids into mitochondria where theyre needed for energy metabolism.[i] Fueling your cells power plants can boost physical and mental energy.

ALCAR is a necessary ingredient for acetylcholine formation.[ii] Which boosts memory, mental alertness, and fluid thought.

The antioxidant properties of Acetyl-L-Carnitine provide neuroprotective qualities, boosts Brain-Derived Neurotrophic Factor (BDNF), and promotes cerebral blood circulation.

Aniracetam is one of the best nootropics available today. Its well-known among experienced nootropics users for reducing anxiety, depression, fear and improving sociability.[iii] But it does so much more.

Aniracetam enhances your brains ability to repair damaged cell membranes. It desensitizes glutamate (AMPA) receptors in your brain.[iv] Which boosts neural signaling by increasing the effectiveness of glutamate. Resulting in better focus and concentration.

Aniracetam also improves memory and recall by releasing 200 300% more acetylcholine in the brain.[v] Which increases focus, and clarity of thought.

Bacopa Monnieri is one of the best nootropics for studying. Researchers at Banaras Hindu University in India showed Bacopa as effective for anxiety as the benzodiazepine drug lorazepam. Unlike benzodiazepines, Bacopa did not cause memory loss. But in fact, it boosted cognition.[vi]

Another study done in Portland Oregon demonstrated that 300 mg of Bacopa per day for 12 weeks:

A valuable addition to any great nootropic stack, CDP-Choline is a multitasker which improves cognition and brain function, improves focus and motivation, and reduces fatigue.

CDP-Choline aids in the synthesis of acetylcholine, and the release of dopamine.[viii] Both neurotransmitters involved in learning and memory.

CDP-Choline also helps in the repair of brain cell membranes. The cytidine in CDP-Choline converts to uridine in your body. And works as a bridge between choline and neuron membrane synthesis. Uridine is needed to synthesize phosphatidylcholine (PC) which is needed to repair damaged neuron membranes.[ix]

Choline is so vital to cognition and nerve function that, without it, we couldnt move, think, sleep or remember anything. And one the best ways to provide your brain and body with the choline it needs is with CDP-Choline.

DHA (docosahexaenoic acid) is an omega-3 fatty acid. DHA is crucial for the healthy structure and function of your brain. Your brain is made up of 60% fat. And much of that fat is DHA.

DHA has the ability to turn on brain-derived neurotrophic factor (BDNF). Improving neuroplasticity leading to better learning and memory. And DHA acts as an anti-inflammatory by reducing the enzyme COX-2.

If you suffer from chronic depression, within a few weeks of adding DHA to your nootropic stack, you should feel the depression lift. Your cognition will be better. Youll think clearer and quicker. Your memory and ability to learn will improve. And youll likely have more energy and motivation.

But it is very likely you wont think to attribute these improvements to adding DHA to your stack. Something else will get the credit.

Lions Mane Mushroom is an ancient Chinese remedy for improving cognitive performance, and overall health.

In our modern world, Lions Mane makes it into some of the top nootropic stacks. Why?

Because Lions Mane stimulates enzyme production that releases Nerve Growth Factor (NGF).[x] It stimulates the repair and creation of neurons (neurogenesis). Boosting neurotransmitters and signaling that effects memory, learning, recall, and mood. And Lions Mane helps eliminate brain fog. Restoring memory and mental alertness. And lowers anxiety and depression symptoms.[xi]

Lions Mane is a great compliment to any nootropic stack including Aniracetam, CDP-Choline and DHA (Omega-3s) for an immediate cognitive boost.

N-Acetyl L-Tyrosine produces the catecholamine-triad of neurotransmitters dopamine, norepinephrine and epinephrine. As your dopamine levels increase, youre better able to concentrate, organize your thoughts, and stay productive.

NALT can be an effective treatment for ADHD symptoms. NALT works in synergy with pharmaceutical drugs like Ritalin and Adderall by boosting extracellular levels of dopamine. Helping these drugs be more effective. And mitigating side effects like crashes when the drug wears off.

N-Acetyl L-Tyrosine also improves memory and cognition under acute stress.[xii] It helps improve decision making, flow state and creativity, cognitive flexibility, and working memory.

NALT is a great addition to any nootropic stack, especially if youre dealing with ADHD.

For more tips on how to deal with ADHD and ADD symptoms, see my post:Best Nootropics for ADHD/ADD

Phosphatidylserine is a favoritenootropicbecause:

Phosphatidylserine (PS) is arguably one of the most effective and important nootropics we have available today. It has a reputation for improving alertness, attention, cognition, memory, recall and mood.[xiii]

Pine Bark Extract is one of the best nootropics around but relatively unknown to the nootropic community. Its a naturally derived standardized extract of French maritime pine bark.

Pine Bark Extract helps prevent decreases in dopamine, norepinephrine, and the glutathione (GSH) and GSH-disulphide reductase (GSSG-R) ratio. Neurotransmitter problems which contribute to hyperactivity in ADHD.[xiv]

Pine Bark Extract helps boost blood flow to and within your brain.[xv] By increasing nitric oxide which helps dilate blood vessels. And helping repair and maintain the health of the lining of blood vessels. Crucial to overall brain health, maintaining signaling pathways and leading to improved learning and memory.

And Pine Bark Extract prevents accumulation of oxidatively damaged proteins. And may reduce the risk of diseases like Parkinsons, Alzheimers, and Huntingtons.

Recommended dosage of Pine Bark Extract containing 95% proanthocyanidins is up to 100 mg 3-times per day.

In Russia, Rhodiola Rosea is widely used as a remedy for fatigue, poor concentration, and decreased memory. Its also believed to make workers more productive.

This adaptogen helps reduce stress and fatigue, increase energy, alertness and stamina, while boosting mental performance under periods of chronic stress. Research shows Rhodiola Rosea can increase attention to detail-oriented tasks by improving concentration over a prolonged period. Making it one of the topnootropics for studying.

Rhodiola Rosea boosts mood by influencing serotonin and norepinephrine levels in your brain, and the feel-good opioids like beta-endorphins. It also helps in neurogenesis by repairing and growing new neurons. As well as activating the synthesis and re-synthesis of ATP, your body and brain cells main energy source.

One more reason to add Rhodiola to your nootropic stack it helps reduce the inflammatory C-reactive protein. And salidroside, one of many components of this incredible herb, protects neurons from oxidative stress-induced cell death.

Sulbutiamine is one favoritenootropics in my stack. Its a synthetic derivative of Vitamin B1 (thiamine). Two Vitamin B1 molecules joined together help thiamine more easily cross the blood-brain barrier.

Sulbutiamine is directly involved in the citric acid cycle that provides adenosine triphosphate (ATP) energy for your mitochondria. It has been shown to improve glutamatergic, cholinergic, and dopaminergic neurological transmissions. It may also increase the density of D1 dopamine receptors.[xvii]

Sulbutiamine also contributes to the production of the enzyme PDH which is essential in making the neurotransmitter acetylcholine.

I love this nootropic because it boosts cognition, memory, decision-making, improves athletic performance, reduces chronic fatigue[xviii] and erectile dysfunction,[xix] and is one of the best antidepressants Ive ever used.[xx]

L-Theanine is an amino acid which naturally occurs in green and oolong tea. Many consider it their favorite nootropic stack when combined with caffeine for the synergistic effect of lowering blood pressure, rejuvenate and relax, boost thinking ability, improve focus and change your mood.

This amazing amino acid:

Most neurohackers report a calming effect within 30 45 minutes of taking L-Theanine. Cognition gets a boost, and energy levels rise without the jitteriness caused by stimulants like caffeine. Some report L-Theanine has stopped their anxiety and panic attacks. (Just dont combine it with anti-anxiety meds like Xanax).

Vinpocetine is often found in some of the premiumnootropic stacks. This semi-synthetic derivative of the lesser periwinkle plant is known for increasing cerebral circulation, taming inflammation and oxidative stress, and boosting alertness, cognition, concentration, memory and mood.

Vinpocetine inhibits the enzyme PDE1 which boosts cerebral blood flow. It blocks the accumulation of sodium in neurons, reduces the toxic effects of oxidative stress, scavenges free radicals, and protects neurons from glutamate and NMDA toxicity.

And by inhibiting PDE1, Vinpocetine increases cAMP and cGMP.[xxiii] Boosting neuroplasticity which enhances cognition and memory.

The B-Vitamins that should be part of every nootropic stack include:

You may not realize the full benefit of a nootropic stack containing CDP-Choline, Acetyl-L-Carnitine, any of the racetams, or any nootropic for that matter without adding a good quality B-Vitamin Complex. Possibly the most important and least expensive addition to your stack.

Some nootropic supplement labels recommend taking it with a meal. The implication behind this recommendation is that the nootropic is fat-soluble. And requires some fat for proper absorption and to increase bioavailability.

Each of the nootropics listed above have links through to a full review which includes information about solubility fat or water soluble.

To be on the safe side, I take one tablespoon of organicunrefined coconut oil with my nootropic stack. This healthy oil provides the fat I need for better bioavailability. And I dont have to worry about taking it with a meal.

Using coconut oil with my stack does not interfere with the water-soluble supplements either. Its a win-win.

Ive tried a lot of different nootropic stacks in the last 10 years. But in late 2015, I finally found one high quality pre-made stack that covered all the bases. That stack is Mind Lab Pro.

I used MLP as the base for my personal nootropic stack throughout 2016 and 2017. And continue to use the same stack in 2018. Its that good.

In fact, in 2017 Opti Nutra, the company that makes Mind Lab Pro upgraded their formula. Their B-Vitamins are now their own proprietary BioGenesis vitamins. Nature-identical nutrients that your body recognize as food.

Then in 2018, Opti Nutra introduced an entire new supplement brand called Performance Lab. The company recognized the demand for more choices when it comes to brain optimization. And the need to support the rest of your body.

Performance Lab offers the pre-formulated nootropic stacks Performance Lab Mind and Performance Lab Energy.

Their nootropic stacks are supported by the Performance Lab Whole-Food Multi containing nature-identical BioGenesis vitamins and minerals for whole-body performance. This multivitamin supplement works very well with Mind Lab Pro as well.

Performance Lab also offers supplement stacks for Vision, Sleep, a Prebiotic, Sports formulas, and a T-Booster for men.

So if youre feeling frustrated in finding the ideal stack, my hope is this page provides the pointers you need to create your optimalnootropic stack.

My attitude on brain optimization is that good enough isnt nearly good enough until Im performing my best. In all areas of life.

The right combination of nootropics in the right amounts have helped me get to the point where I feel Im performing better than ever.

Near the beginning of this page we identified the main points that lead to cognitive improvement; cognition, decision-making, focus, thinking, memory, anxiety, depression, energy, motivation, brain repair and maintenance.

What I love about the nootropicsoutlined on this page is that it covers each of those categories.

But to help you fine-tune your nootropic stack further. You may want to take a look at each of the following posts I wrote on individual areas of brain optimization.

Best Nootropics for Learning & Memory

Best Nootropics for Social Anxiety

Best Nootropic for ADHD

Best Nootropics for Depression

Best Nootropics for Motivation

Best Nootropics for Hacking a Flow State

13 Nootropics to Boost BDNF

Psychobiotics: The Gut-Brain Connection

REFERENCES

[i] Berg J.M., Tymoczko J.L., Stryer L.Biochemistry. 5th edition. New York: W H Freeman; 2002. (source)

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Lithium Orotate Nootropics Expert

Lithium helps prevent mood swings, is anti-anxiety and antidepressant, promotes neurogenesis, protects from neurodegenerative disease, and is anti-aging

Lithiumis a soft, silvery-white alkali metal so reactive (it sparks when it touches water) that its not found in nature. Instead, its found in mineral compounds and in mineral water.

Cosmologists believe that lithium was one of the 3 elements synthesized in the Big Bang.[i] So its been around for a long time.

Most of us associate lithium with treating mental illnesses like bipolar disorder and mania. Or the lithium-ion battery in our phone. Which has a tendency to blow up occasionally.

Turns out that the anti-psychotic medication lithium isnt even a drug. Its actually a mineral. And part of the same family of minerals that include potassium and sodium.

As a nootropic, micro-dosing lithium provides some amazing anti-aging benefits. Recent research shows that low-dose lithium may also help slow the progression of neurodegenerative diseases like Alzheimers, dementia and Parkinsons disease.

Low-dose lithium also helps neurogenesis and memory. And is a mood stabilizer.

Here well investigate daily or frequent use of Lithium Orotateas a nootropic, and how it benefits cognitive health.

Lithium helps:

Lithiumis an alkali mineral and one the trace elements considered essential for both animal and human reproductive health, and general health and wellness.

Discovered as a chemical element in 1817, lithiums first recorded modern medical use was in 1871 for the treatment of mania.

But the use of lithium for therapeutic use goes back to ancient Greek and Roman times. People enjoyed soaking in alkali springs to help with physical and mental illness.

People have been using mineral springs for therapeutic use ever since. Lithia Springs in Douglas County, Georgia was so popular that people came for miles just to drink the water.

The Sweet Water hotel, a luxury 500-room resort was opened in 1887. And attracted famous authors, business people and prominent politicians who came for the springs health benefits. The name Lithia stems from water rich in lithium.

Studies from around the world have shown the critical health benefits of lithium. One study using data from 27 Texas counties from 1978 1987 found that rates of suicide, homicide and rape were significantly higher in counties whose drinking water contained little or no lithium.[v]

Another study of lithium levels in tap water in 18 municipalities in Japan showed standard mortality ratios lower in places with higher lithium levels.[vi]

Yet another study conducted in Texas in 2013 confirmed the original findings in that state. Drinking water samples from 226 counties found a correlation between lithium levels and suicide rates.[vii]

Researchers who conducted meta-analyses of lithium levels and public drinking water suggested increasing lithium levels of drinking water could potentially reduce the risk of suicide, and justify administering lithium to tap water.[viii]

An article in the Lancet in 1949 by John Cade is credited for the modern medical use of lithium as an effective treatment for manic psychosis.[ix]

The United States FDA approved high dose lithium carbonate and lithium citrate in 1970 for the treatment of bipolar disorder. Carbonic acid and citric acid are mineral carriers used to transport lithium throughout your body.

Doctors also prescribe lithium off-label for treating migraines, seizure disorders and psychosis usually after other treatments have failed.

But as we dig deeper into the most recently published research on lithium, we realize this trace element is essential for optimal health and brain function.

The lithium we get from our diet prevents many neurological and psychiatric problems. Micro-dosing lithium as a nootropicwith a supplement like Lithium Orotate can help make up for the what we dont get from our food and water.

Lithium is naturally available from fish, processed meat, milk, dairy products, eggs, potatoes and vegetables. Your typical dietary intake of lithium can range from 2 600 mcg. Amounts vary depending on where the food is grown.

Lithium helps brain health and function in several ways. But two in particular stand out.

Lithium inhibits the enzyme glycogen synthase kinase-3 (GSK-3). This inhibition upregulates brain-derived neurotrophic factor (BDNF), and insulin-like growth factor-1 (IGF-1) which stimulates neural stem cells to produce new neurons in the hippocampus.[x]

When neural stem cells produce new neurons in the hippocampus, mood and memory work as designed. But a breakdown in neurogenesis results in mood disorders.

Lithium has long been known to control mania and stabilize mood in bipolar patients. But it was not generally thought of as an antidepressant. Researchers in Tel Aviv provided the first evidence that inhibiting GSK-3 exerted a rapid antidepressant effect in mice.[xi]

Another team at Howard Hughes Medical Institute in Pennsylvania showed that feeding mice chow laced with low-dose lithium for 15 days produced a dose-dependent antidepressant effect.[xii]

Lithium induced gene transcription in the hippocampus, amygdala and hypothalamus. All areas implicated in depression, anxiety, bipolar disorder, autism and schizophrenia.

Glutamate plays a major role in the synaptic plasticity needed for learning and memory.[xiii] But over-activity of glutamate on its NMDA receptors causes neuron death and is implicated in Alzheimers, Huntingtons and Parkinsons disease. Lithium inhibits this overactivity.[xiv]

Lithium also increases the production of a neuroprotective protein called bcl-2.[xv] Researchers maintain that lithium is the only medication that has been demonstrated to significantly increase bcl-2 in several brain areas.

Lithium has also recently been evaluated in preventing and treating traumatic brain injury. In a study conducted in 2014, Dr. Peter Leeds stated that lithium had demonstrated robust beneficial effects in experimental models of Traumatic Brain Injury (TBI). These include decreases in TBI-induced brain lesion, suppression of neuroinflammation, protection against blood-brain barrier disruption, normalization of behavioral deficits, and improvement of learning and memory, among others.[xvi]

In 1985, the United States EPA estimated that dietary intake of lithium from food in the USA varied from 0.6 to 3.1 mg per day.[xvii] For comparison, people who live in the Andes in Northern Argentina consume 2 to 30 mg per day, with 2 3 mg just from drinking water.[xviii]

As your dietary sodium and caffeine increases, so does lithium excretion in urine which increases your requirement for this essential trace mineral.

Your exposure to stress and toxins from things like mercury, aspartame, MSG, Bisphenol A (BPA) and other excitotoxins also raise cortisol and other stress hormones. Increasing your need for more water-soluble nutrients like B-vitamins, magnesium, zinc and lithium.

Low lithium levels are associated with

Depression and anxiety increase

Memory and learning ability decline

Insomnia increases

Sensitivity to stress and chronic pain increase

Natural healing processes decline

Adequate daily intake of lithium could help prevent many mental and neurological diseases due to this trace minerals effects on nervous system metabolism. And its anti-inflammatory and antioxidant effects.

The clinical research and studies on the neuroprotective benefits of lithium are so overwhelming, some scientists are beginning to ask why isnt everyone using lithium?

Heres a summary of how micro-dosing lithium using Lithium Orotate can benefit your brain.

The benefits of supplementing with lithium go far beyond just optimizing cognitive health. Lithium also helps decrease insulin resistance, helps in treatment of alcoholism and other addictions, supports bone health, balances your circadian rhythm and more.

My personal experience with Lithium Orotate has made me a believer in micro-dosing lithium. Im Adult ADD and deal with mood swings from time to time.

If Im going around the bend because something upset me, I take 5 mg of Lithium Orotate. Within 15 minutes my mood stabilizes and I feel normal again. Consistent use puts me in a happy mood.

Many others report youll feel the results taking a low dose of lithium quickly. But for some, the full effect can take anywhere from 1 to 3 weeks. Micro-dosing 5 10 mg of lithium daily results in consistent results within a month or two for some. Ive experienced great results within a couple of days.

So if you lash out at people in anger, and dont fully understand why you get so angry it could be your lithium levels are low.

Many neurohackers with depression and anger issues notice results quickly. Within the first couple of days you should feel more calm, relaxed, and experience less stress.

Keep in mind that lithium at any dose is not for everyone. But if you get adequate lithium from your diet and water, and still experience some of the mood swings talked about in this review, you could be dealing with other issues. You should know within a couple of hours of supplementing with low-dose lithium if this supplement is for you.

For some, Lithium Orotate means feeling excited about life for the first time in a long time. Anxiety and social anxiety are no longer a problem. Life is more fun and enjoyable.

Some say Lithium Orotate works better than any prescription that theyve ever tried to treat severe depression. It provides a nice, smooth mood balance without all the toxicity associated with mega-doses of lithium carbonate.

If youre dealing with PTSD or mild insomnia, you may want to try Lithium Orotate. Focus could improve, racing thoughts diminish and motivation levels could increase. Youll have more coping ability.

A study at McMaster University in Canada set out to determine the effects on hippocampus volume in 14 bipolar patients who received lithium therapy.

The researchers examined the effects of lithium on hippocampal volumes and memory performance and recall over 2 4 years. The patients had not received any type of medication prior to using lithium.

The study found increases in hippocampus volume over time. And evidence of improvement of verbal memory performance over the 4-year measurement period.

The researchers concluded that the results of the study were consistent with the literature stating the neuroprotective effects of lithium. And that long-term treatment of lithium is associated with preservation of memory and recall due to increased hippocampus size.[xxi]

24 adults recovering from heroin or methamphetamine addiction participated in a study in San Diego. Group A received 400 mcg per day of lithium taken orally for 4 weeks. The placebo Group B naturally took a non-active placebo.

Subjects completed a mood test questionnaire containing questions about their ability to think, work, mood and emotions. For the lithium group, mood test scores increased steadily and significantly during the 4 week period.

The lithium group also reported significantly increased levels of happiness, friendliness and energy. Group B showed no improvement during the same period.

The researchers concluded that low-dose lithium provided a mood-improving and stabilizing effect.[xxii]

In this study, 42 alcoholic patients were treated with Lithium Orotate during alcohol rehabilitation in a private clinical setting for six months. The data was collected from clinical practice records for the 10 years following the initial study.

The patients received 150 mg of Lithium Orotate daily for six months along with calcium orotate, magnesium orotate, bromelain and essential phospholipids.

Ten of the patients had no relapse from 3 10 years. 13 patients stayed sober from 1 3 years. The remaining patients relapsed between 6 12 months.

The researchers concluded that Lithium Orotate therapy was safe in treating addiction with minor adverse side effects.[xxiii]

Lithium retains a grim and undeserved reputation. Likely because it was originally associated with serious mental illness. And like most medications, lithium can produce serious side effects if not monitored properly.

Lithium carbonate or lithium chloride salts are typically prescribed for long-term control of bipolar disorder at 900 1200 mg per day. The major problem with such high doses of lithium are some very serious and debilitating side effects.

For nootropic use, we suggest Lithium Orotate which typically contains only 5 mg of elemental lithium. Lithium Orotate is orotic acid combined with lithium.

Orotic acid reportedly makes the lithium more bioavailable than lithium carbonate. The lithium is released once it crosses the blood-brain barrier. So youll get the benefits of lithium supplementation while avoiding the toxic side effects of high doses.[xxiv]

Lithium Orotate recommended dose is 5 mg two or three times per day. See Available Forms for more on lithium amounts in nootropic supplements.

Many neurohackers use Lithium Orotate only as needed. For example, when feeling anxious or in the middle of a mood swing.

For someone with bipolar disorder or manic disorders, increasing to two 5 mg tablets up to 3-times per day may be more effective.

Naturopathic doctors suggest stacking 1,000 mg of Omega-3 and 400 UI of Vitamin E (as mixed tocopherols) each day youre using Lithium Orotate.

Do not confuse Lithium Orotate with lithium carbonate. The carbonate version of lithium is only available by prescription and comes with a host of side effects.

Lithium Orotate at low doses is non-toxic and lab tests are not required to monitor your lithium levels because it does not show up in blood samples.

Lithium Orotate should not be used if you are dealing with significant renal or cardiovascular disease, severe dehydration or sodium depletion, or if youre taking diuretics or ACE inhibitors.

Do not use Lithium Orotate if you are pregnant or breast-feeding.

You should check with your doctor if you are on any medication before using Lithium Orotate.

Mother Nature has already put the antipsychotic drug lithium in drinking water. And you get some lithium from food depending on where its grown.

Supplemental Lithium Orotate typically comes in 120 or 130 mg capsules or tablets containing 5 mg of elemental lithium.

Lithium Orotate 5 mg 2 or 3 times per day.

We recommend using Lithium Orotate as anootropic supplement if youre feeling anxious or depressed. Or experiencing mood swings.

Your bodydoes notmake lithium on its own. So you must get this essential trace mineral from your diet, or a supplement like Lithium Orotate.

Lithium combined with orotic acid makes Lithium Orotate which readily crosses theblood-brain barrier, and you should feel its effects within 15 20 minutes of taking it.

Lithium Orotate is especially effective if youre feeling stressed, or mentally over-worked. Your brain uses lithium faster and it needs to be replaced. Which you can do by using Lithium Orotate.

Lithium Orotate is great if you are ADHD because lithium calms the hyperactivity in your brain.

Supplementing with lithium does not change your state of consciousness. It simply helps bring you back to feeling normal and happy.

We suggest trying Lithium Orotate as a nootropic supplement with your first dose at 5 mg and see how you react. If you experience no negative reaction, try another 5 mg in a few hours. Up to 3 5 mg doses per day.

Youll likely experience the full benefits of Lithium Orotate within a week of consistent use.

REFERENCES

[i] Boesgaard A.M., Steigman G. (1985). “Big bang nucleosynthesis Theories and observations”. Annual Review of Astronomy and Astrophysics. Palo Alto, CA. 23: 319378. (source)

[ii] Swann A.C. Norepinephrine and (Na+, K+)-ATPase: evidence for stabilization by lithium or imipramine. Neuropharmacology. 1988 Mar;27(3):261-7. (source)

[iii] Herbert V., Colman N. Release of vitamin binding proteins from granulocytes by lithium: vitamin B12 and folate binding proteins. Advances in Experimental Medicine and Biology. 1980;127:61-78. (source)

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Nootropic – Wikipedia

Nootropics ( noh–TROP-iks) (colloquial: smart drugs and cognitive enhancers) are drugs, supplements, and other substances that may improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.[1] While many substances are purported to improve cognition, research is at a preliminary stage as of 2018, and the effects of the majority of these agents are not fully determined.

The use of cognition-enhancing drugs by healthy individuals in the absence of a medical indication spans numerous controversial issues, including the ethics and fairness of their use, concerns over adverse effects, and the diversion of prescription drugs for nonmedical uses, among others.[1][2] Nonetheless, the international sales of cognition-enhancing supplements exceeded US$1 billion in 2015 when global demand for these compounds grew.[3]

The word nootropic was coined in 1972 by a Romanian psychologist and chemist, Corneliu E. Giurgea,[4][5] from the Greek words (nous), or “mind”, and (trepein), meaning to bend or turn.[6]

In 2008, the most commonly used class of drug was stimulants, such as caffeine.[7] Manufacturer’s marketing claims for dietary supplements are usually not formally tested and verified by independent entities.[8]

The use of prescription stimulants is especially prevalent among students.[9] Surveys suggest that 0.74.5% of German students have used cognitive enhancers in their lifetime.[10][11][12] Stimulants such as dimethylamylamine and methylphenidate are used on college campuses and by younger groups.[13] Based upon studies of self-reported illicit stimulant use, 535% of college students use diverted ADHD stimulants, which are primarily intended for performance enhancement rather than as recreational drugs.[14][15][16] Several factors positively and negatively influence an individual’s willingness to use a drug for the purpose of enhancing cognitive performance. Among them are personal characteristics, drug characteristics, and characteristics of the social context.[10][11][17][18]

The main concern with pharmaceutical drugs is adverse effects, which also apply to nootropics with undefined effects. Long-term safety evidence is typically unavailable for nootropics.[13] Racetams piracetam and other compounds that are structurally related to piracetam have few serious adverse effects and low toxicity, but there is little evidence that they enhance cognition in people having no cognitive impairments.[19]

In the United States, dietary supplements may be marketed if the manufacturer can show that the supplement is generally recognized as safe, and if the manufacturer does not make any claims about using the supplement to treat or prevent any disease or condition; supplements that contain drugs or advertise health claims are illegal under US law.[20]

Systematic reviews and meta-analyses of clinical human research using low doses of certain central nervous system stimulants found enhanced cognition in healthy people.[21][22][23] In particular, the classes of stimulants that demonstrate cognition-enhancing effects in humans act as direct agonists or indirect agonists of dopamine receptor D1, adrenoceptor A2, or both types of receptor in the prefrontal cortex.[21][22][24][25] Relatively high doses of stimulants cause cognitive deficits.[24][25]

Racetams, such as piracetam, oxiracetam, and aniracetam, which are often marketed as cognitive enhancers and sold over-the-counter. Racetams are often referred to as nootropics, but this property is not well established.[31] The racetams have poorly understood mechanisms, although piracetam and aniracetam are known to act as positive allosteric modulators of AMPA receptors and appear to modulate cholinergic systems.[32]

According to the US Food and Drug Administration, “Piracetam is not a vitamin, mineral, amino acid, herb or other botanical, or dietary substance for use by man to supplement the diet by increasing the total dietary intake. Further, piracetam is not a concentrate, metabolite, constituent, extract or combination of any such dietary ingredient. […] Accordingly, these products are drugs, under section 201(g)(1)(C) of the Act, 21 U.S.C. 321(g)(1)(C), because they are not foods and they are intended to affect the structure or any function of the body. Moreover, these products are new drugs as defined by section 201(p) of the Act, 21 U.S.C. 321(p), because they are not generally recognized as safe and effective for use under the conditions prescribed, recommended, or suggested in their labeling.”[33]

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Premium nootropics, cognitive enhancers and smart supplements.

New or a connoisseur, dont settle for less than the best for your nootropics journey.

Value your brain.

Nootropics are synthetic compounds that help you to accomplish your goals through improved cognition, better recall and crystal-clear focus.

Safe and secure.

Discover what works for you safely. We provide only the best supported compounds, alongside third-party testing and complete transparency.

Order with confidence.

Free delivery on all U.S. orders over $50 and on international orders over $200.

Stay focused.

Clear your stress.

Get things done.

Boost your mood.

Fuel your brain.

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Nootroo – The Gold Standard In Nootropics

Synergistic Effects

Researchers studying deficient brains in older populations are constantly working to activate the cholinergic system, as the neurotransmitter acetylcholine is directly implicated in memory. Normally, administering choline alone can increase cholinergic transmission and raise the levels of acetylcholine in the brain.

However, in some older patients, their cholinergic systems are so deteriorated, that they are unable to turn the choline into acetylcholine. The scientists theorized that if they could administer choline, while simultaneously administering a compound that could correct for the critical age-related neuronal deficiencies, it might enable the choline to be properly metabolized.

When they learned that piracetam enables the central nervous system to function more effectively, the researchers decided to run an experiment on aged rats. They administered choline, piracetam, alone as well as the combination of the two.

Both choline and piracetam alone seemed to have a somewhat positive, albeit limited effect. However, when they combined piracetam and choline, the results were considered “profound.” See the dramatic difference the combination makes in the gold bar labeled “C+P” in the accompanying graph.

Our Gold & Silver stacks are based on the principles behind this synergistic combination of ingredients.

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Nootroo – The Gold Standard In Nootropics

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Nootropics Depot features an extensive range of dietary supplements and nootropic compounds. Nootropics Depot offers the best nootropics and natural extracts from industry leading manufacturers including Nammex, Verdure Sciences, Embria Health Science, and Ixoreal Biomed.

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See the latest updates to our nootropics blog below to begin exploring the vast world of nootropics and dietary supplements.

What is Cognizin Citicoline?Not every form of choline readily makes it

What Is 7,8-Dihydroxyflavone?7,8-Dihydroxyflavone, also known as 7,8-DHF,

What Is Creatine?Creatine is

COMPARING RHODIOLA ROSEA EXTRACTS: ROSAVINS VS. SALIDROSIDERhodiola rosea, more commonly known as golden root or rose root…

BERBERINE: A LOOK AT THE POTENTIAL BENEFITS OF THIS VERSATILE SUPPLEMENTBerberine is a bright yellow alkaloid that is found in a variety of plants…

HERICIUM ERINACEUS: WHICH IS THE BEST LION’S MANE MUSHROOM FOR YOU?Hericium erinaceus, also known as lions mane mushroom…

NITRIC OXIDE SUPPLEMENTS REVIEWED: L-CITRULLINE, AGMATINE AND AAKGNitric oxide is a very interesting neurotransmitter within the body…

GANODERMA LUCIDUM: WHICH IS THE BEST RED REISHI MUSHROOM FOR YOU?We are often asked which Red Reishi extract is best…

COMPREHENSIVE GUIDE TO THE BEST ANTI-AGING SUPPLEMENTSLet’s facilitate a healthy aging process, rather than trying to completely halt it…

WHICH IS THE BEST CORDYCEPS MUSHROOM FOR YOU?Did you know not all Cordyceps mushroom extracts are made the same way?

BACOPA MONNIERI: BACOGNIZE VS. SYNAPSA – WHICH AYURVEDIC HERB IS RIGHT FOR YOU?Commonly known as the waterhyssop or brahmi…

THE NOOTROPIC SYNERGY OF CAFFEINE AND L-THEANINEOne of the most popular natural nootropic stacks is a simple combination of L-theanine and caffeine…

L-CITRULLINE VS. L-CITRULLINE DL-MALATE: WHICH IS BEST?L-citrulline is one of three dietary amino acids involved in the urea cycle…

SHILAJIT: A LOOK AT THIS AMAZING AYURVEDIC SUPPLEMENTShilajit is a sticky, tar-like substance often appearing dark brown in color…

ULTIMATE GUIDE TO CHOLINE SUPPLEMENTSCholine is an essential nutrient that is found in a variety of foods…

ULTIMATE GUIDE TO KRILL AND FISH OIL SUPPLEMENTSFish oil supplements are going to provide a very solid base to build a nootropics stack upon…

WHAT YOU MIGHT NOT KNOW ABOUT PANAX GINSENG SUPPLEMENTSGinseng is one of the most well known herbs in the world…

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