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US Navy Veterans Mesothelioma Advocate Now Offers a Navy Veteran with Mesothelioma Direct Access to Attorney Erik Karst if the Law Firm of Karst von…

NEW YORK, Jan. 2, 2020 /PRNewswire/ -- The US Navy Veterans Mesothelioma Advocate says, "A US Navy Veteran who has just been diagnosed with mesothelioma and their family deserve immediate answers to their questions. We provide a unique service that includes immediate access to attorney Erik Karst of the law firm of Karst von Oiste to answer these questions-especially regarding compensation. If a Navy Veteran with mesothelioma or their family would like direct answers to their questions from some of the nation's leading mesothelioma attorneys, please call us anytime at 800-714-0303.

"The amazing lawyers at the law firm of Karst von Oisteproduce some of the nation's top compensation results for US Navy Veterans with mesothelioma. We are urging a Navy Veteran with mesothelioma or their family members to call us anytime at 800-714-0303 so we can provide you with immediate access to attorney Erik Karst and his colleagues at the law firm of Karst von Oiste. A 'free' book, kit or package about mesothelioma is frequently a law firm's clever way of getting your contact information. Attorney Erik Karst wants to make certain a Navy Veteran with mesothelioma receives the best possible compensation results."www.karstvonoiste.com/

The US Navy Veterans Mesothelioma Advocate is also offering to assist a Navy Veteran with mesothelioma to organize the questions about how, where and when they were exposed to asbestos. They call this free service the 'list' and it is this specific information that becomes the basis for a mesothelioma compensation claim as they would like to discuss anytime at 800-714-0303.

Additionally, the Advocate will help a Navy Veteran with mesothelioma explore the possibilities of VA benefits to make certain nothing has been overlooked. "We want to do everything possible to ensure a Navy Veteran with mesothelioma gets the best possible compensation settlement results that might exceed a million dollars as well as any possible VA benefit. A Navy Veteran with mesothelioma in any state or their family members can call us anytime at 800-714-0303." https://USNavyMesothelioma.Com

For a listing of all VA Medical Centers in each state please review the VA's website: https://www.va.gov/directory/guide/allstate.asp.

For current information about the US Navy fleet of combat ships please review their website on this topic:http://www.navy.mil/navydata/our_ships.asp.

According to the Veterans Administration some of the worst types of asbestos exposure occurred when a US Navy Veteran was stuck on their ship in dry dock or undergoing a major overhaul in shipyard located in Washington, Virginia, Connecticut, California, Maine, Massachusetts, Pennsylvania, New York, Louisiana, Hawaii or Georgia. http://www.karstvonoiste.com/

For more information about mesothelioma please refer to the National Institutes of Health's web site related to this rare form of cancer:https://www.cancer.gov/types/mesothelioma.

Contact:Michael Thomas800-714-0303230055@email4pr.com

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US Navy Veterans Mesothelioma Advocate Now Offers a Navy Veteran with Mesothelioma Direct Access to Attorney Erik Karst if the Law Firm of Karst von...

German Researchers Deem Heated Chemotherapy Safe Option for Pleural Mesothelioma – Mesothelioma.net Blog

December 30, 2019

Heated chemotherapy administered following removal of cancerous tumors has long been viewed as an effective treatment for patients diagnosed with peritoneal malignant mesothelioma, but its use in pleural mesothelioma has not been as accepted. But physicians from the University of Munich recently completed a study that led them to conclude that the procedure, known as HITHOC, is a safe therapeutic option when patients are carefully selected.

HITHOC stands for Hyperthermic Intrathoracic Chemotherapy, and its use in the treatment of pleural mesothelioma has been discussed for years as an option for patients who are already undergoing mesothelioma surgery. Though not all patients are good candidates, for those who are, the study found that the protocol provides longer survival time.

Patients diagnosed with pleural mesothelioma have tumors that form in the pleural lining that surrounds the lungs. As the tumors grow, breathing becomes more difficult. Eventually the malignant cells metastasize throughout the chest, and eventually throughout the body.

The median overall survival time for those diagnosed with pleural mesothelioma is generally shorter than that of those diagnosed with peritoneal mesothelioma, and this is due in large part to the challenge of surgical removal. Pleural tumors can work their way into irregular spaces within the chest cavity, making it more difficult for all of the malignant material to be removed. Using chemotherapy intraoperatively provides the opportunity to bathe any remaining cancerous cells directly with the heated chemotherapy liquid, thus extending the time between the cancers eventual return.

The researchers found that of the 71 pleural mesothelioma patients who had diseased pleural tissue removed and then had the HITHOC treatment, the procedure was most successful in those diagnosed with epithelioid mesothelioma. Those diagnosed with the rare and more aggressive sarcomatoid cell type lived about half as long, with the median survival for those with epithelioid tumors being 17.9 months and those with the sarcomatoid subtype living just 9.2 months. Successful removal of cancerous tissue was also an important indicator, with those who had complete resection experiencing a median survival of 28.2 months and those with incomplete resections having a median survival of less than half that amount of time.

If you or someone you love has been diagnosed with malignant pleural mesothelioma and you need more information on available treatment options, the Patient Advocates at Mesothelioma.net can help. Contact us today at1-800-692-8608.

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Facing The New Year With Malignant Mesothelioma – Mesothelioma.net Blog

December 31, 2019

For those who have been diagnosed with malignant mesothelioma and those who love them the holidays can be particularly challenging. While those around you are raucously celebrating the New Year and wishing each other all good things, patients and their families look forward with a certainty that the coming year will bring more pain and grief.The happiness of others serves as a stark contrast to your own feelings. Dealing with what is called anticipatory grief is particularly hard while others around you are joyous.

Anticipatory grief is what both mesothelioma patients and those who care for them and about them begin to experience from the time of diagnosis, and it lasts until the time that the patient finally succumbs to the disease. Though there may be a significant reprieve based on successful treatment and the particular patients prognosis, nothing can change the fact that malignant mesothelioma is always considered terminal.

This type of grief is extremely difficult. Though you may be grateful for the opportunity to attend to arrangements, to spend time with loved ones imparting important messages, and even to indulging in pursuing bucket list items, it is always with the knowledge of the hard days and sadness that lie ahead.

The New Year puts pressure on everybody to be cheerful and optimistic, as January 1sttends to hold the promise of improvement and a new start. Mesothelioma patients may be too exhausted or ill to participate, and this can put pressure on their loved ones, who may want to celebrate but who feel guilt at doing so. Those loved ones may also be stricken by their anticipation of the mourning that is to come.

According to psychologists, the holiday season heightens the sense of loss for mesothelioma patients. There are so many memories tied up with them, and because there are so many traditions involved it is easy to look forward to the next celebration and picture the empty chair at the table. The best way to manage this grief during the holidays is to be open and honest about the impending loss so that you can fully appreciate the time that you have left. Take the time to talk about what is important and to say what is important now. That will make what may be the last holiday together both memorable and meaningful.

If you or someone you love has been diagnosed with malignant mesothelioma and you need support, the Patient Advocates at Mesothelioma.net can help. Contact us today at1-800-692-8608.

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Facing The New Year With Malignant Mesothelioma - Mesothelioma.net Blog

Tributes to National Express bus driver, who tragically dies of cancer aged just 29 – Birmingham Live

A heartbroken family has paid tribute to a 'bright' and 'clever' Walsall bus driver who tragically died from cancer at just 29.

Isobel Galls devastated dad, Roger, has spoken of his pain after her death on New Years Eve (December 31) following a two-year battle with Mesothelioma.

He told Black Country Live that the keen violinist who was part of the Walsall Orchestra would be greatly missed by all that knew her.

The 56-year-old said: "She was bright, clever and she would always put others before herself. She would always worry about people, too.

"Isobel was a keen violinist, an artist and was well-known for her job. She will be greatly missed by everyone that knew her."

The 29-year-old who was from Brownhills also leaves behind an older brother, Richard, her sister, Rebekah, and her mum, Ianthe.

Tributes from across have flooded in following the tragic news of her death, which has been branded devastating.

One wrote: "Heart goes out to the family, friends and colleagues of the sad passing of Isobel Gall who was National Express West Midlands driver and an Enthusiast who passed away after a brave battle with cancer on New Year's Eve at the young age of 29.

"I think I can speak on behalf of fellow enthusiasts and bus and coach drivers from Ireland that our thoughts are prayers are with Isobel, her family, close friends and colleagues at this sad time.

"Rest in Peace Isobel. Go where the bus takes you in heaven above."

And another wrote: "Walsall bus driver Isobel Gall, who was well-liked and loved by those who knew and worked with her, lost her courageous battle with cancer on December 31, 2019. Our thoughts and condolences go out to Isobel's family and close friends at this difficult time."

Mr Gall said Isobel campaigned for awareness during her two-year battle and had taken part in events such as Race for Life in a bid to raise awareness of the disease.

National Express West Midlands has been contacted for comment.

In the UK about 2500 people a year are diagnosed with mesothelioma. It is also known as 'diffuse' or 'malignant' mesothelioma. Mesothelioma is a form of cancer that affects the mesothelium. The mesothelium is a thin membrane that lines the inner surface of the chest wall or abdomen.

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The mesothelium also surrounds organs within these cavities, for example, the heart, lungs and intestines. It is far more common to have mesothelioma in the chest than in the abdomen. There is approximately one case of peritoneal mesothelioma to every 12 cases of pleural mesothelioma.

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Tributes to National Express bus driver, who tragically dies of cancer aged just 29 - Birmingham Live

Mesothelioma Compensation Center Is Open During the Holidays to Make Certain A Power Plant or Energy Worker with Mesothelioma Has Direct Access to…

NEW YORK, Dec. 31, 2019 /PRNewswire/ -- The Mesothelioma Compensation Center says, "We are available to help a power plant or oil refinery or any type of energy worker with mesothelioma or their family members-always. Mesothelioma does not take time off for weekends or holidays neither do we. We are 100% focused on doing everything possible to see to it that a power plant, refinery or any type of energy worker receives the very best possible financial compensation results if they have mesothelioma-as we would be happy to discuss anytime at 800-714-0303.

"To get the financial compensation job done we have endorsed the law firm of Karst von Oiste and their founding partner Erik Karst. Attorney Erik Karst and his colleagues at the law firm of Karst von Oiste are responsible for over a billion dollars in financial compensation results for their clients, and they are some of the nation's most skilled mesothelioma attorneys. Frequently the lawyers at the law firm of Karst von Oiste can expedite financial compensation for a power plant or energy worker.For direct access to attorney Erik Karst of the law firm of Karst von Oiste please call us anytime at 800-714-0303."www.karstvonoiste.com/

To make certain the best possible financial compensation settlement results happen for a power plant, oil refinery or any type of energy worker the Mesothelioma Compensation Center is now offering a free service they call the list. The 'list' documents how, where and when a person with mesothelioma was exposed to asbestos. It is this vital information that becomes the basis for a mesothelioma compensation claim as they would be happy to discuss anytime at 800-714-0303.https://MesotheliomaCompensationCenter.Com

The Mesothelioma Compensation Center is the most quoted source in the nation for the best mesothelioma compensation for the following types of people who have been diagnosed mesothelioma:

According to the CDC, the states indicated with the highest incidence of mesothelioma includeMaine,Massachusetts,Connecticut,New Jersey,Pennsylvania,Ohio,West Virginia,Virginia,Michigan,Illinois,Minnesota,Louisiana,Washington, andOregon.

However, a power plant, refinery or energy worker with mesothelioma could live in any state including California, Texas, New York, Florida,Illinois, Kentucky, Tennessee, Georgia, Alabama, Nebraska, North Dakota, Wyoming, Colorado, Nevada, New Mexico, Utah, Arizona, Idaho, or Alaska. https://mesotheliomacompensationcenter.com/

The Mesothelioma Compensation Center specializes in assisting high-risk workers who have been diagnosed with mesothelioma. High-risk groups for exposure to asbestos include the US Navy Veterans, power plant workers, shipyard workers, oil refinery workers, public utility workers, chemical plant workers, nuclear power plant workers, oil and gas field production workers, hydro-electric workers, plumbers, electricians, welders, millwrights, pipefitters or machinists. In most instances people with mesothelioma were exposed to asbestos in the 1950's, 1960's, 1970's, or 1980's.www.karstvonoiste.com/

For more information about mesothelioma, please refer to the National Institutes of Health's web site related to this rare form of cancer:https://www.cancer.gov/types/mesothelioma

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Michael Thomas800-714-0303230043@email4pr.com

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Mesothelioma Compensation Center Is Open During the Holidays to Make Certain A Power Plant or Energy Worker with Mesothelioma Has Direct Access to...

Mesothelioma Victims Center Is Urging a Navy Veteran or Person with Mesothelioma to Call Them Anytime During the Holidays for Direct Access to…

NEW YORK, Dec. 30, 2019 /PRNewswire/ -- The Mesothelioma Victims Center says, "We fear that most people with mesothelioma never get properly compensated. We know this because we receive complaints about law firms that promised the moon to a person with mesothelioma and then failed to deliver on their promises. We are open during the holidays to make certain a person with mesothelioma or their family have access to resources they need. As we would like to discuss anytime at 800-714-0303-mesothelioma compensation and help for people with this rare cancer is a one-shot deal.

"If you put off starting the compensation process or impulsively hire a local car accident attorney a person with mesothelioma might get shortchanged. About a year ago we endorsed the law firm of Karst von Oiste and their founding partner Erik Karst because these remarkable mesothelioma attorneys work overtime for their clients with this rare cancer caused by asbestos. Frequently the lawyers at the law firm of Karst von Oiste can expedite financial compensation for their clients. For direct access to attorney Erik Karst of the law firm of Karst von Oiste please call us anytime at 800-714-0303."www.karstvonoiste.com/

The Mesothelioma Victims Center is now offering to a help a person with mesothelioma anywhere in the nation to hopefully dramatically increase their potential compensation by assisting them in listing how, where and when they were exposed to asbestos. It is this incredibly vital information that becomes the basis for a mesothelioma compensation claim and this service is free as the Mesothelioma Victims Center would be happy to discuss anytime at 800-714-0303.https://MesotheliomaVictimsCenter.Com

High-risk work groups for exposure to asbestos include Veterans of the US Navy, power plant workers, shipyard workers, steel mill workers, oil refinery workers, factory workers, plumbers, electricians, welders, millwrights, pipefitters, miners, auto mechanics, machinists, pulp or paper mill workers, printers, firemen, rail road workers and construction workers. In most instances people with mesothelioma were exposed to asbestos in the 1950's, 1960's, 1970's, or 1980's.http://MesotheliomaVictimsCenter.Com

According to the CDC the states indicated with the highest incidence of mesothelioma includeMaine,Massachusetts,Connecticut,Maryland,New Jersey,Pennsylvania,Ohio,West Virginia,Virginia,Michigan,Illinois,Minnesota,Louisiana,Washington, and Oregon.

However, based on the calls the Mesothelioma Victims Center receives a person with mesothelioma could live in any state including New York, Florida, California, Texas, Illinois, Ohio, Iowa, Indiana, Missouri,Kentucky,Tennessee,North Carolina, Georgia, Alabama, Mississippi, Oklahoma,Arkansas,Kansas,Nebraska,North Dakota,Wyoming,Colorado,Nevada,New Mexico,Arizona,Idaho, or Alaska.www.karstvonoiste.com/

For more information about mesothelioma please refer to the National Institutes of Health's web site related to this rare form of cancer:https://www.cancer.gov/types/mesothelioma.

Media contact: Michael Thomas 230048@email4pr.com800-714-0303

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Mesothelioma Victims Center Is Urging a Navy Veteran or Person with Mesothelioma to Call Them Anytime During the Holidays for Direct Access to...

Mesothelioma – Symptoms and causes – Mayo Clinic

Overview

Malignant mesothelioma (me-zoe-thee-lee-O-muh) is a type of cancer that occurs in the thin layer of tissue that covers the majority of your internal organs (mesothelium).

Mesothelioma is an aggressive and deadly form of cancer. Mesothelioma treatments are available, but for many people with mesothelioma, a cure isn't possible.

Doctors divide mesothelioma into different types based on what part of the mesothelium is affected. Mesothelioma most often affects the tissue that surrounds the lungs (pleura). This type is called pleural mesothelioma. Other, rarer types of mesothelioma affect tissue in the abdomen (peritoneal mesothelioma), around the heart and around the testicles.

Mesothelioma care at Mayo Clinic

Signs and symptoms of mesothelioma vary depending on where the cancer occurs.

Pleural mesothelioma, which affects the tissue that surrounds the lungs, causes signs and symptoms that may include:

Peritoneal mesothelioma, which occurs in tissue in the abdomen, causes signs and symptoms that may include:

Signs and symptoms of other types of mesothelioma are unclear, since these forms of the disease are very rare.

Pericardial mesothelioma, which affects tissue that surrounds the heart, can cause signs and symptoms such as breathing difficulty and chest pains.

Mesothelioma of tunica vaginalis, which affects tissue surrounding the testicles, may be first detected as swelling or a mass on a testicle.

See your doctor if you have signs and symptoms that worry you. Signs and symptoms of mesothelioma aren't specific to this disease and, due to the rarity of mesothelioma, are more likely to be related to other conditions. If any persistent signs and symptoms seem unusual or bothersome, ask your doctor to evaluate them. Tell your doctor if you've been exposed to asbestos.

In general, cancer begins when a series of changes (mutations) happens in a cell's DNA. The DNA contains the instructions that tell a cell what to do. The mutations tell the cell to grow and multiply out of control. The abnormal cells accumulate and form a tumor.

It isn't clear what causes the initial genetic mutations that lead to mesothelioma, though researchers have identified factors that may increase the risk. It's likely that cancers form because of an interaction between many factors, such as inherited conditions, your environment, your health conditions and your lifestyle choices.

Most mesotheliomas are thought to be related to asbestos exposure. Asbestos is a mineral that's found naturally in the environment. Asbestos fibers are strong and resistant to heat, making them useful in a wide variety of applications, such as in insulation, brakes, shingles, flooring and many other products.

When asbestos is broken up, such as during the mining process or when removing asbestos insulation, dust may be created. If the dust is inhaled or swallowed, the asbestos fibers will settle in the lungs or in the stomach, where they can cause irritation that may lead to mesothelioma. Exactly how this happens isn't understood. It can take 20 to 60 years or more for mesothelioma to develop after asbestos exposure.

Most people with asbestos exposure never develop mesothelioma. This indicates that other factors may be involved in determining whether someone gets mesothelioma. For instance, you could inherit a predisposition to cancer or some other condition could increase your risk.

Factors that may increase the risk of mesothelioma include:

As pleural mesothelioma spreads in the chest, it puts pressure on the structures in that area. This can cause complications, such as:

Reducing your exposure to asbestos may lower your risk of mesothelioma.

Most people with mesothelioma were exposed to the asbestos fibers at work. Workers who may encounter asbestos fibers include:

Ask your employer whether you have a risk of asbestos exposure on the job.

Follow all safety precautions in your workplace, such as wearing protective equipment. You may also be required to shower and change out of your work clothes before taking a lunch break or going home. Talk to your doctor about other precautions you can take to protect yourself from asbestos exposure.

Older homes and buildings may contain asbestos. In many cases, it's more dangerous to remove the asbestos than it is to leave it intact. Breaking up asbestos may cause fibers to become airborne, where they can be inhaled. Consult experts trained to detect asbestos in your home. These experts may test the air in your home to determine whether the asbestos is a risk to your health. Don't attempt to remove asbestos from your home hire a qualified expert.

Jan. 15, 2019

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Mesothelioma - Symptoms and causes - Mayo Clinic

The US Navy Veterans Mesothelioma Advocate is Open Throughout the Holidays to Ensure a Navy Veteran with Mesothelioma Gets a Game Plan from Erik Karst…

NEW YORK, Dec. 26, 2019 /PRNewswire/ -- The US Navy Veterans Mesothelioma Advocate isopen throughout the holiday season because mesothelioma does not observe holidays-neither do they. Navy Veterans make up about one third of all people who will be diagnosed with mesothelioma in the United States each year. The Advocate's top priority is that a Navy Veteran with mesothelioma receive the best possible financial compensation results. Frequently a Navy Veteran might receive over a million dollars in compensation. These lump sum compensation settlements do not involve the suing navy. Rather these financial settlements involve makers of machinery, equipment, pumps, pipes or insulation that contained asbestos as the Advocate would be happy to discuss anytime at 800-714-0303.

The US Navy Veterans Mesothelioma Advocate has endorsed the law of Karst von Oiste to assist a Navy Veteran with confirmed mesothelioma in every state. The amazing lawyers at the law firm of Karst von Oiste are responsible for over a billion dollars in financial compensation settlements for US Navy Veterans or people with mesothelioma or asbestos exposure illnesses and they work overtime for their clients. The lawyers at the law firm of Karst von Oiste also make house calls to visit a Navy Veteran in their home to discuss compensation face to face with the Veteran. For direct access to attorney Erik Karst the founding partner please call 800-714-0303-anytime.www.karstvonoiste.com/

The US Navy Veterans Mesothelioma Advocate says, "We are now offering to assist a Navy Veteran with mesothelioma to document how, where and when they were exposed to asbestos. We call this free service the 'list' and it can dramatically increase the financial compensation for a Navy Veteran with mesothelioma and or their family as we would be happy to discuss anytime at 800-714-0303."

"Most Navy Veterans with mesothelioma almost never receive VA disability payments or other VA benefits. This is separate from mesothelioma compensation which as we mentioned might exceed a million dollars. We will assist a US Navy Veteran with mesothelioma to get a VA disability claim filed. Our participation in this service is free to a Navy Veteran with mesothelioma as we would be happy to discuss anytime at 800-714-0303."https://USNavyMesothelioma.Com

For specific information about US Navy warships and submarines please review their website on this topic:https://www.navy.mil/navydata/our_ships.asp.

For a listing of all VA Medical Centers in each state please review the VA's website:https://www.va.gov/directory/guide/allstate.asp.

The states with the highest incidence of mesothelioma include Maine, Massachusetts, Connecticut, Maryland, New Jersey, Pennsylvania, Ohio, West Virginia, Virginia, Michigan, Illinois, Minnesota, Louisiana, Washington, and Oregon.

However, based on the calls the US Navy Veterans Mesothelioma Advocate receives a US Navy Veteran diagnosed with mesothelioma could live in any state including New York, Florida, California, Texas, New Hampshire, Vermont, Delaware, Iowa, Indiana, Missouri, Kentucky, Tennessee, North Carolina, Georgia, Alabama, Mississippi, Oklahoma, Arkansas, Nebraska, North Dakota, Montana, Wyoming, Colorado, Nevada, New Mexico, Arizona, Idaho, or Alaska. http://www.karstvonoiste.com/

For more information about mesothelioma, please refer to the National Institutes of Health's web site related to this rare form of cancer:https://www.cancer.gov/types/mesothelioma

Media Contact:Michael Thomas800-714-0303230049@email4pr.com

SOURCE US Navy Veterans Mesothelioma Advocate

U.S. Navy Veterans Mesothelioma Advocate

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The US Navy Veterans Mesothelioma Advocate is Open Throughout the Holidays to Ensure a Navy Veteran with Mesothelioma Gets a Game Plan from Erik Karst...

1.5 Million UK Buildings are Exposed to Asbestos; Mesothelioma Lawyers are Helping the Victims – BO Herald

Asbestos is banned in almost every country. The United Kingdom has also banned asbestos 20 years ago. But it is still a reason behind a large number of occupational deaths in the country. Last year, almost 5,500 people died in the UK due to asbestos.

There is an estimate that six million tons of asbestos is still available in 1.5 million buildings in the country. These buildings can be schools, hospitals, colleges, and government buildings.

Though asbestos is banned in the UK since 1999, its exposure is causing many diseases including lung cancer, asbestosis, and mesothelioma. Almost 80% of the schools and 74% of the universities in the country are expected to contain asbestos in their buildings. Despite a large exposure to the asbestos, the school authorities are failing to manage the asbestos in their perimeters according to legal requirements. A large number of students and teachers may be exposed to asbestos in the country. West Virginia also has many sites that are exposed to asbestos. Asbestos victims there are visiting https://gpwlaw-wv.com/ to get legal assistance from a reputed West Virginia Mesothelioma Lawyer.

Asbestos causes mesothelioma and it is a deadly disease. Mesothelioma patients are entitled to compensation from the people responsible for the asbestos exposure. Mesothelioma lawyers provide legal assistance to the patients by fighting their compensation cases in the court. The compensation gained through the lawyers can be used by the victims to cover medical bills and other expenses raised due to asbestos exposure.

Ankita is a well experienced badminton player and has won many championships. She intends to build a bright career in the media industry as well. She is a sports freak who loves to cover the latest news on Sports and Indoor Games.

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1.5 Million UK Buildings are Exposed to Asbestos; Mesothelioma Lawyers are Helping the Victims - BO Herald

Congressional Hearing Examines Asbestos Detection in Talc – Mesothelioma.com

On December 5, the House Committee on Oversight and Reform held a hearing to examine the cancer-causing properties of asbestos-contaminated talc products and methods for asbestos detection. The hearing came after Johnson & Johnsons talcum powder products were again under fire for asbestos contamination.

In October 2019, 33,000 bottles of Johnson & Johnson baby powder were recalled due to trace levels of chrysotile asbestos contamination. Despite the U.S. Food and Drug Administrations (FDAs) findings of contamination, Johnson & Johnson was unable to detect asbestos in its products and disputed the claims. The committee called for better, more sensitive testing methods to detect asbestos, in order to protect public health and keep dangerous products off store shelves.

The hearing, titled Examining Carcinogens in Talc and the Best Methods for Asbestos Detection, aimed to identify methods for better asbestos testing in products and hold Johnson & Johnson accountable for its distribution of asbestos-contaminated talcum powder. Johnson & Johnson CEO Alex Gorsky was set to attend the hearing, but declined an invitation to voluntarily testify under oath.

According to Congressman Raja Krishnamoorthi, Chairman of the Oversight Subcommittee on Economic and Consumer Policy, laboratory tests have shown Johnson & Johnson talc-based products have been contaminated with asbestos for decades. The subcommittee discussed evidence Johnson & Johnson employees knew about the asbestos contamination during this time. Evidence alleged company employees even discussed suppressing the use of more sensitive asbestos-detection methods.

In the hearing, Krishnamoorthi also stated the company has been repeatedly asked to label its powder with a cancer warning due to these findings. Instead, the subcommittee alleged, Johnson & Johnson increased a marketing plan to people of color.

The company also commissioned a market survey consultant to understand the public perception of the powders name. Because the consultant found women preferred cornstarch-based products and had an aversion to talc, the company prominently featured a cornstarch label on those products. However, the company didnt label talc clearly on its talc-based baby powder.

During the hearing, Dr. William Longo, a scientist for Materials Analytical Services, LLC, testified as a witness. He delivered the findings of his laboratory, Materials Analytical Services, which served as an independent laboratory to conduct asbestos testing of Johnson & Johnson products.

He analyzed samples of Johnson & Johnsons baby powder from the 1940s to the 2000s, along with the companys current products. He tested the products for asbestos using the Heavy Liquid Separation (HLS) technique, which is more sensitive than the testing methods used by Johnson & Johnson. Overall, Dr. Longo discovered 65% of all samples tested positive for asbestos.

Dr. Longo explained in his testimony, The cosmetic talc industry has, in that time, accumulated hundreds, if not thousands of testing results that report no detectable or quantifiable asbestos. These reports, regarded by the manufacturers as negative, are very misleading as they result from analytical and methodological techniques with poor detection limits.

Despite these findings, Johnson & Johnson continues to argue its products are asbestos-free. The company further claimed the tests conducted by Dr. Longos lab did not actually test for asbestos, but rather found another substance.

In the FDAs laboratory testing of the products, they utilized a standard method of testing rather than HLS techniques. The tests still indicated the presence of chrysotile asbestos fibers, but Dr. Longo indicated amphibole asbestos fibers could have also been found if the FDA used a more advanced testing method.

Dr. Jacqueline Moline, a physician at Feinstein Institutes for Medical Research at Northwell Health, offered insights from 33 mesothelioma patients who were exposed to asbestos from talcum powder.

Dr. Moline noted talcum powder was the only instance of asbestos exposure among all 33 patients in the study. She further stated mesothelioma is deemed a signature disease, as it almost always is the result of exposure to asbestos.

To this day, theyre finding asbestos in talcum powder on the shelves, and its putting thousands, if not millions, of people at risk, said Dr. Moline in her testimony.

Dr. Moline affirmed there is no safe level of asbestos in talc products or any products, as the mineral is a proven carcinogen.

In more recent years, the FDA has increased efforts in testing for asbestos in talc and cosmetic products. In 2008 and 2010, records showed the FDA selected AMA Laboratories Inc. to conduct asbestos testing of cosmetic products. AMA detected asbestos in Johnson & Johnson baby powder, stating that detecting asbestos in cosmetics requires the most sensitive laboratory tests available.

Despite this, Dr. Longo doesnt believe AMA used the most sensitive tests during this time. He argued asbestos fibers would have been detected sooner if the most advanced technology was used in testing procedures.

In the future, Dr. Longo believes HLS should be used as the standard for asbestos testing in the United States. Dr. Longo explained HLS has already been adopted as the international standard for its sensitivity.

Due to the microscopic nature of asbestos fibers, hundreds of millions of fibers may be present in a given sample, so it is essential for the most advanced technology to be used to identify its presence. Even when using the most advanced technology, it can be difficult to confirm asbestos is present in a given product, as the threshold is 4,500 fibers per gram.

At this very moment, I am sending a document request to Johnson & Johnson seeking answers, said Krishnamoorthi in his closing remarks of the panel.

In response to this hearing, the FDA also continues to call for better test methods in order to protect public health.

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Congressional Hearing Examines Asbestos Detection in Talc - Mesothelioma.com

Mesothelioma Victims Center Is Open During Holidays to Ensure a Person with Mesothelioma Gets on the Spot Compensation Advice from Attorney Erik Karst…

NEW YORK, Dec. 23, 2019 /PRNewswire/ -- The Mesothelioma Victims Center says, "We are appealing to a person with mesothelioma or their family members to call us anytime at 800-714-0303. Mesothelioma does not observe holidays or weekends-neither do we. In fact-the holidays are in many instances the best time for a person with mesothelioma or their family to call us-because the family is together. Our top priority for a person with mesothelioma is that they receive the very best financial compensation settlement results that depending upon how the person with this rare cancer was exposed to asbestos-could exceed a million dollars.

"To get the financial compensation job done we have endorsed the amazing lawyers at the law firm of Karst von Oiste and their founding partner Erik Karst. Attorney Erik Karst and his colleagues at Karst von Oiste are responsible for over a billion dollars in financial compensation for people with mesothelioma or asbestos exposure illnesses. The dedicated lawyers at the law firm of Karst von Oiste are always available to assist a person with mesothelioma in any state or their family members. For direct access to attorney Erik Karst of the law firm of Karst von Oiste please call us anytime at 800-714-0303."www.karstvonoiste.com/

The Mesothelioma Victims Center is now offering a free vital service that is designed to increase the financial compensation for a person with mesothelioma. They call this service the 'list' and it has been designed to assist a person with mesothelioma recall there where, how, and when they were exposed to asbestos. It is this vital information that becomes the basis for a mesothelioma compensation claim as they would be happy to discuss at 800-714-0303-anytime.https://MesotheliomaVictimsCenter.Com

Important Note for a person with advanced or late stage mesothelioma from the Mesothelioma Victims Center: "If you or your family member has advanced mesothelioma please call us anytime at 800-714-0303 so we can make arrangements to visit you/your loved one in your home so we can help document your exposure to asbestos. Your compensation depends on having as much information as possible about your exposure to asbestos-and we want to help."https://MesotheliomaVictimsCenter.Com

According to the CDC the states indicated with the highest incidence of mesothelioma includeMaine, Massachusetts,Connecticut, Maryland,New Jersey,Pennsylvania,Ohio,West Virginia,Virginia, Michigan,Illinois,Minnesota,Louisiana,Washington, andOregon.

However, based on the calls the Mesothelioma Victims Center receives a person with mesothelioma could live in any state including New York, Florida, California, Texas, Iowa, Indiana, Missouri, North Carolina, Kentucky, Tennessee, Georgia, Oklahoma, Arkansas, Kansas, Nebraska, North Dakota, Wyoming, Colorado, New Mexico, Utah, Nevada, Arizona, Idaho, or Alaska.www.karstvonoiste.com/

High-risk work groups for exposure to asbestos include US Navy Veterans, power plant workers, shipyard workers, oil refinery workers, steel mill workers, manufacturing/factory workers, pulp or paper mill workers, plumbers, electricians, auto mechanics, machinists, miners, construction workers, insulators, rail road workers, roofers, or firemen. As a rule, these types of workers were exposed to asbestos in the 1950's, 1960's, 1970's, or 1980's. https://MesotheliomaVictimsCenter.Com

For more information about mesothelioma please refer to the National Institutes of Health's web site related to this rare form of cancer:https://www.cancer.gov/types/mesothelioma.

Media contact:Michael Thomas230047@email4pr.com800-714-0303

SOURCE Mesothelioma Victims Center

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Mesothelioma Victims Center Is Open During Holidays to Ensure a Person with Mesothelioma Gets on the Spot Compensation Advice from Attorney Erik Karst...

Mesothelioma: Immunotherapy a Potential Alternative to Chemotherapy – Gilmore Health News

Researchers have presented their findings in a Phase 3 trial showing that immunotherapy may be a viable alternative to chemotherapy for mesothelioma patients.

Lung X-Ray

In the PROMISE-meso trial, scientists compared the efficacy of immunotherapy with pembrolizumab, a checkpoint inhibitor, against standard chemotherapy. They did this in mesothelioma patients who had relapsed after receiving first-line treatment. Their findings showed that these patients responded to immunotherapy, almost four times more.

Sadly, the observed greater responses failed to lead to a delay in the progression of the disorder or improved survival chances.

Read Also: Warning! Talcum Powder Might Be Responsible for Mesothelioma a Rare Form of Cancer

These findings are disappointing but, as in previous studies, some patients benefitted from immunotherapy for long periods, said study author Dr. Sanjay Popat, of Royal Marsden Hospital NHS Foundation Trust in London, UK. If we can find out how this happens, we will have a better idea of which patients should preferentially receive this treatment over chemotherapy.

In spite of the mediocre results, Popat said that immunotherapy showed enough potential to serve as an alternative to chemotherapy.

Results from the PROMISE-meso trial were presented at the 2019 edition of the European Society of Medical Oncology (ESMO) annual meeting.

Mesothelioma is not one of the most common forms of cancer, but it ranks among the most fatal.

An estimate has it that there are more than 30,000 diagnoses in a year on average. More than 25,000 people die as a result of the disorder annually.

Patients typically die within two years of being diagnosed with mesothelioma.

Exposure to asbestos fibers contributes hugely to the incidence of this cancer form. Researchers say this is responsible for more than 80 percent of cases.

Mesothelioma does not develop immediately after asbestos exposure. Inflammation of the mesothelial cells in the lung occurs at the initial stage. It usually takes decades before cells turn cancerous.

There has been a reduction in the incidence of this condition in the USA, Australia, and Western Europe. This decline is a result of strict regulations in these places, as regards asbestos.

The incidence of asbestos deaths has dropped gradually over the years in America. Death rates are somewhat stable in Western Europe.

Later bans on asbestos in other countries have kept death rates high in many of them. Mortality due to mesothelioma is still rising in Japan and Eastern Europe.

Read Also: How Does Cancer Manipulate The Immune System?

Dr. Federica Grosso of the Mesothelioma and Rare Cancers Unit of Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo in Alessandria, Italy said that new cases and deaths were common in some hotspots in the country. She stated that the incidence of mesothelioma in one of these places, Casale Monferrato, is more than 20 times higher than in other parts of Italy.

Casale Monferrato had the worlds largest asbestos plant before it was shut down in 1987.

The worldwide number of deaths is expected to rise as people exposed to asbestos before it was banned continue to be diagnosed many years later, Grosso said.

She stated that there is a partial or full asbestos ban in only 66 countries across the globe. The bulk of the current production takes place in middle and lower-income countries.

Patients have very limited options currently for treating mesothelioma. In fact, a combination of pemetrexed and platinum derivatives is the only approved treatment regimen.

No effective, standard second-line treatment is available at the moment for people with this disorder. A patient may only receive another course of the approved regimen or other medications, such as gemcitabine (Gemzar) or vinorelbine (Navelbine).

Read Also: Nanoparticles A Potential Cure For Cancer According To Study

The research team studied 144 patients who had advanced pre-treated cases of mesothelioma in Phase 3 PROMISE-meso trial. These individuals were randomly selected to receive 200mg of pembrolizumab once every three weeks or standard chemotherapy featuring gemcitabine and vinorelbine.

For pembrolizumab, the median overall survival was 10.7 months. This compared fairly well with 11.7 months reported for chemotherapy.

The group that received immunotherapy also showed slightly fewer adverse events. There was one fatality in each of the groups.

The hope is that these findings may lead to a new treatment. The results stress the need to investigate why immunotherapy seems to produce a response in some patients and not in others.

Although we did not see better survival with immunotherapy in the PROMISE-meso study, the responses are encouraging and the results of the ongoing trials of checkpoint inhibitor treatment in earlier stage mesothelioma will be very important to clinicians, said Grosso, who emphasized the need for better first and second-line treatments for this thoracic cancer form.

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Mesothelioma: Immunotherapy a Potential Alternative to Chemotherapy - Gilmore Health News

St. Louis Jury Sides With Johnson & Johnson in Talc Case – The New York Times

ST. LOUIS A St. Louis jury has ruled in favor of Johnson & Johnson in the latest of several lawsuits alleging that the companys baby powder caused ovarian cancer.

The jury ruled 9-3 late Friday, denying 56-year-old Vickie Forrests allegation that more than 30 years of use of the talcum-based powder caused her illness. Forrest, of St. Louis, was diagnosed with stage 2 ovarian cancer in 2012 and is in remission after surgery and chemotherapy, her attorneys said.

Its disappointing that J&J is going to see this as approval of their continued sale of talc-based baby powder that harms women, Ted Meadows, one of Forrests lawyers, said in a statement.

The lawsuit is among several filed on behalf of thousands of women who claim Johnson & Johnson's talcum powder contributed to their ovarian cancer. Other lawsuits have claimed that talc products caused mesothelioma. Juries have awarded billions of dollars in damages but some verdicts have been overturned because of jurisdictional issues.

Johnson & Johnson has consistently argued that its baby powder is safe and does not cause cancer, and has appealed cases where it has lost.

Johnson & Johnson did not immediately respond to phone and email messages Monday.

St. Louis courts have often been friendly to plaintiffs. In July 2018, jurors in St. Louis awarded $4.7 billion to 22 women and their families who said asbestos in Johnson & Johnsons baby powder caused their cancers.

Talc is mined from mineral deposits that can be contaminated with asbestos. Johnson & Johnson has said its powder is routinely tested to ensure there's no asbestos.

But in October, Johnson & Johnson recalled 33,000 bottles of baby powder after Food and Drug Administration testing revealed trace amounts of asbestos. The company disputed the findings and said earlier this month that its own testing, performed by two independent labs, found no traces of asbestos.

___

Associated Press reporter Margaret Stafford in Kansas City, Missouri, contributed to this report.

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St. Louis Jury Sides With Johnson & Johnson in Talc Case - The New York Times

Malignant Mesothelioma Market To Tell Apart Steadfast Growth Within The Course – Bulletin Line

In developed countries, discretionary research funding for cancer is on a rise. Increased investments towards development of better treatment against malignant mesothelioma is observed globally. Persistence Market Researchs new report on global market for malignant mesothelioma predicts that governments will increase their focus towards creating awareness about mesothelioma in the future.

The globalmalignant mesothelioma marketis expected to incur favorable boost from increased healthcare spending witnessed in multiple parts of the world, coupled with availability of better treatment prognosis for mesothelioma.

In 2017, the global malignant mesothelioma market is expected to reach a value of US$ 338 Mn. The report observes that increasing use of asbestos for commercial purposes is fuelling the incidence of malignant mesothelioma among people. By the end of 2025, the global market for malignant mesothelioma is anticipated to have soared at7.5% CAGR, reaching an estimatedUS$ 604 Mn in value.

Global Malignant Mesothelioma Market Prominent Trends

Studies focused on cause of malignant mesothelioma are being publicized to boost awareness. Through such work, people are becoming more aware, particularly with respect to association of the HOXB4 gene is stopping the maturation of mesothelioma tumor.

Overall, the global market for malignant mesothelioma is also witnessing an increased adoption of combination therapies. Many companies are promoting the cumulative use of chemotherapy and immune-oncology procedures in treatment of malignant mesothelioma.

In addition to this, malignant mesothelioma is gaining incidence among men. Exposure to asbestos is likely to remain concentrated to male demographics of the world. Increased exposure to such toxic elements is aggravating the incidence of mesothelioma in men.

Key players in the global malignant mesothelioma market are also collaborating with leading research organizations to develop combination drugs on mesothelioma, the approval of which is drawing highest regard of authorities such as the FDA.

Company Profiles

Malignant Mesothelioma Market Forecast Key Findings

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Malignant Mesothelioma Market To Tell Apart Steadfast Growth Within The Course - Bulletin Line

Industrial Workers Affected due to Asbestos Exposure at Workplace have been Searching Mesothelioma Lawyer Nationwide in the US – Seekers Time

In a US-based survey, it has come to notice that industrial workers affected due to exposure to asbestos at industrial units have been searching for a mesothelioma lawyer nationwide. It is really important for a Mesothelioma victim to get the highest compensation that one can only get if he has complete knowledge about it. Industrial workers are becoming aware that a local firm might not have the knowledge, experience, or certifications related to solving mesothelioma cases.

A lot of people working in the industrial units in the West Virginia region of the Southern US have been taking the help of online mesothelioma law firms in order to hire the best lawyer for themselves. Technology has played a crucial role in enabling the asbestos affected industrial workers to look for mesothelioma lawyer services worldwide. The increasing job hazards at industrial units due to the failure to follow proper safety measures have been increasing the incidents related to mesothelioma on a large scale.

As the number of cases related to mesothelioma cancer has been rising in the US, it has become a common thing to see a number of people hiring a mesothelioma lawyer to get justice. The demand for West Virginia mesothelioma lawyers has been rising and people are largely visiting the online platform of the law firm of Goldberg, Persky & White P.C. (https://gpwlaw-wv.com/).

The firm provides an experienced lawyer and helps industrial workers to get a good amount of compensation. The law firm of Goldberg, Persky, & White P.C. has been receiving a lot of cases from different corners of the US and it is simply because industrial workers have been searching for experienced workers nationwide to get excellent law service.

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Industrial Workers Affected due to Asbestos Exposure at Workplace have been Searching Mesothelioma Lawyer Nationwide in the US - Seekers Time

Mesothelioma: What Is Malignant Mesothelioma Cancer?

What Is Mesothelioma?

Mesothelioma is an incurable, asbestos-related cancer that typically affects the lining of the lungs. However, mesothelioma tumors can develop in the lining of the abdominal cavity or heart.

Symptoms of mesothelioma appear when tumors spread, grow and press against the chest wall and the abdominal cavity. Chest pain and shortness of breath are the most common symptoms.

A balanced mesothelioma diet can help ease your symptoms and speed recovery. Get a free nutrition guide with quick and easy recipes that can help improve your quality of life.

A biopsy is the only mesothelioma test that confirms a diagnosis. Doctors may use additional diagnostic procedures. An early mesothelioma diagnosis may increase a patients eligibility for all treatment options.

Most people initially undergo a basic chest X-ray to check for any abnormalities. If an abnormal growth is detected, doctors will recommend a more detailed imaging scan such as a PET scan, CT scan or MRI.

If cancer is suspected, doctors will recommend taking a sample of tissue, also knowns as a biopsy. Doctors use this tissue sample to definitively confirm the presence of malignant mesothelioma cells.

Blood tests may be used but do not confirm the presence of mesothelioma. Researchers are evaluating if blood tests can aid in the early diagnosis of at-risk former asbestos workers.

Doctors use at least five staging systems to stage pleural mesothelioma. The IMIG staging system is preferred. No universal staging system exists for the other mesothelioma types.

Asbestos exposure is the primary cause of mesothelioma. People exposed to asbestos at home, work or in the military have a higher risk of developing the disease.

A person inhales or swallows microscopic airborne asbestos fibers.

The asbestos fibers become lodged in the lining of the lungs, abdomen or heart.

Embedded fibers damage mesothelial cells and cause inflammation.

Over time, tumors form on the damaged mesothelium, leading to mesothelioma.

People most at risk of developing mesothelioma handled asbestos for a prolonged period of time or were exposed to large amounts of asbestos as part of their career.

Secondhand exposure is also common, especially among the spouses and children of people who worked with asbestos.

Firefighters, construction workers, power plant workers, shipyard workers and others are among these types of workers.

U.S. Navy veterans are most at risk. Army, Marine Corps, Air Force and Coast Guard veterans also face health risks.

Spouses, children and others who lived with a person who was regularly exposed to asbestos fibers are at risk.

Compensation may be available for those diagnosed with mesothelioma. Connect with a top attorney today to see if you qualify.

The stages of mesothelioma range from 1 to 4 and are based on tumor size and location.

Early-stage mesothelioma is usually more confined to one site, while late-stage mesothelioma shows tumors spreading beyond the chest or abdominal cavity. Staging is an important part of determining treatment.

The cancer is localized. Surgery is most effective at this stage. Survival rate is higher. A patients median life expectancy at stage 1 is 22.2 months.

Tumors have spread from the original location and moved into adjacent structures. Surgery is still an option. Median life expectancy at stage 2 is 20 months.

Cancer has spread into the regional lymph nodes. Surgery may be an option. The patients median life expectancy at stage 3 is 17.9 months.

Tumors have spread into distant organs. Chemotherapy and immunotherapy ease symptoms. Median life expectancy at stage 4 is 14.9 months.

The four types of mesothelioma cancer are identified by the location in the body where tumors develop. Pleural and peritoneal types of mesothelioma are the most common. Pericardial mesothelioma accounts for 1% of cases.

Prognosis, symptoms and treatment options vary by mesothelioma type.

There are three cell types of mesothelioma named for the cancer cells found in the tumors: Epithelioid, sarcomatoid and biphasic. Some are more common and respond well to treatments. Others are rarer and more resistant to therapies.

These cells are the most responsive to treatment. This type of mesothelioma accounts for 70% of mesothelioma diagnoses. It also leads to improved prognosis and life expectancy.

Cells of this type are least responsive to treatment. Patients with these cell types have poorer diagnoses and shorter life expectancies. This mesothelioma type accounts for 10% of all cases.

This is a combination of epithelioid and sarcomatoid cells. Its less responsive to treatment. Prognosis and life expectancy depend on the ratio of both cell types. It accounts for 30% to 40% of cases.

Mesothelioma cancer is treated with conventional therapies such as surgery, chemotherapy and radiation. But not every patient is eligible for each type of mesothelioma treatment. Some patients also opt for emerging cancer treatments, including clinical trials, and alternative therapies.

This therapy is used for diagnosing, removing tumors or easing pain. It offers the greatest chance of survival for patients with strong health and limited cancer spread.

More than 70% of patients undergo chemotherapy. The therapys strong drugs shrink tumors and kill cancer cells, but it also presents severe treatment side effects.

The therapy can be used at any cancer stage. Doctors perform it to reduce pain and slow tumor growth. It is often combined with surgery and chemotherapy.

Researchers and doctors offer these experimental therapies across the nation to eligible patients. Clinical trials lead to new or improved treatments.

Doctors who focus on mesothelioma at specialty treatment centers provide patients the best chances of extending life and improving prognosis.

Mesothelioma specialists encompass a number of specialties, including surgery, medical and radiation oncology, radiology, pathology and palliative care. All can be part of a patients treatment plan. Working with an experienced mesothelioma doctor can make all the difference.

The most-regarded treatment centers attract people from across the country. Renowned for their cutting-edge technology and groundbreaking research, these centers can connect you with a multidisciplinary team of physicians with years of experience in treating asbestos-related diseases.

Most doctors and oncologists have never encountered mesothelioma because it is a rare cancer.

A 2009 study published in the Journal of General Internal Medicine shows cancer care requires the technical knowledge and skills of specialty physicians such as medical oncologists, surgeons and radiation oncologists.

The prognosis for mesothelioma is not good. The life expectancy for most patients is about 12 months after diagnosis. Those who can undergo multimodal therapy, which is a combination of two or more treatments, have an improved prognosis.

Factors that most affect mesothelioma prognosis are stage and cell type. Age, gender and exposure history also affect outlook. Younger patients and women have a better mesothelioma prognosis than older men. People diagnosed with the peritoneal mesothelioma type also have a higher chance of survival.

Patients can improve prognosis by eating a nutrient-rich diet, staying healthy, undergoing cancer treatments and making healthier lifestyle choices such as quitting smoking.

Legal and financial options for mesothelioma patients and their families can provide financial compensation to pay medical bills, cover lost wages and other expenses. A mesothelioma lawyer can review your case, so you receive the highest compensation.

A mesothelioma patient can file a personal injury lawsuit. The estate of the patient who died from mesothelioma can file a wrongful death lawsuit.

Bankrupt asbestos companies established trust funds to provide compensation for people exposed to asbestos because of company negligence.

Because the U.S. military relied heavily on asbestos, veterans diagnosed with mesothelioma may be eligible for financial and medical benefits.

Quick Fact: $180,000 is the median value for mesothelioma claims, according to a 2010 report from the RAND Corporation, a nonprofit institution that conducts research and analysis on asbestos bankruptcy trusts.

Many forms of support are available for mesothelioma patients, survivors, loved ones and families.

Mesothelioma survivors, caregivers and family members often need a place where they can share their ongoing struggles and amazing accomplishments. We offer a support group, hosted by a licensed mental health counselor, that offers a safe place for all mesothelioma survivors.

You and your loved ones can advocate for others who are going through the same cancer journey. Getting involved in the move to ban asbestos and raise mesothelioma awareness can have long-lasting and positive effects.

Request a comprehensive mesothelioma guide to gain a deeper understanding of the cancer and how you can help your loved one during this difficult time. We can provide you with a free must-read books that answer frequently asked questions about mesothelioma.

Get all the information you need to make an informed decision after receiving a mesothelioma diagnosis. You will get free access to valuable resources and services for finding treatment, doctors, compensation and much more.

Common Questions About Mesothelioma

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Mesothelioma: What Is Malignant Mesothelioma Cancer?

Mesothelioma Causes, Symptoms, Treatment & Prognosis

Mesothelioma facts

What is mesothelioma?

Mesothelioma is a rare form of cancer (malignancy) that most frequently arises from the cells lining the sacs of the chest (the pleura) or the abdomen (the peritoneum). Pleural mesothelioma is the most common form, often becoming apparent with symptoms in the chest area such as chest pain, cough, and/or shortness of breath. Shortness of breath often occurs due to a large pleural effusion (fluid in the thoracic cavity). Peritoneal mesothelioma is much less common. This can affect the organs in the abdomen, and its symptoms are related to this area of the body, that is, abdominal swelling, nausea, vomiting, and bowel obstruction. The rarest form of mesothelioma is pericardial mesothelioma, which involves the sac surrounding the heart.

There are two major cell types of mesothelioma, epithelial and sarcomatoid. Sometimes both of these cell types can be present, also referred to as biphasic. The sarcomatoid type is rarer and occurs in only about 15% of cases; it portends a poorer prognosis. In very rare cases, mesothelioma can originate from benign, non-malignant cells. Surgery cures this so-called benign mesothelioma.

There are many causes of chest pain. A serious form of chest pain is angina, which is a symptom of heart disease and results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion), aortic aneurysm dissection, myocarditis, esophageal spasm, esophagitis, rib injury or disease, anxiety, and other important diseases. Do not try to ignore chest pain and "work (or play) through it." Chest pain is a warning to seek medical attention.

What are mesothelioma symptoms?

Most people present with complaints of shortness of breath. They also can have complaints of chest pain and cough. Patients may also be asymptomatic, with the disease discovered by physical exam or an abnormal chest X-ray.

As the disease progresses, shortness of breath increases, and weight loss, decreased appetite, and night sweats can develop. Local invasion by the tumor can result in changing of voice, loss of function of the diaphragm, and symptoms specific to the area and involvement of adjacent structures.

What causes mesothelioma?

Most people with malignant mesothelioma have worked on jobs where they breathed asbestos. Usually, this involves men over 40 years of age. Others have been exposed to asbestos in a household environment, often without knowing it. The number of new cases of mesothelioma has been relatively stable since 1983, the same time that the U.S. Occupational Safety and Health Administration (OSHA) instituted restrictions on asbestos. In Europe, the number of new cases of mesothelioma continues to rise.

How much asbestos exposure does it take to get mesothelioma?

An exposure of as little as one or two months can result in mesothelioma 30 or 40 years later and in some cases, as much as 70 years later.

How long does it take after asbestos exposure for mesothelioma to show up?

People exposed in the 1940s, '50s, '60s, and '70s are now being diagnosed with mesothelioma because of the long latency period of asbestos disease.

How do health care professionals diagnose mesothelioma?

Pathological examination from a biopsy diagnoses mesothelioma. A health care professional removes tissue. Then a pathologist places it under a microscope and makes a definitive diagnosis and issues a pathology report. This is the end of a process that usually begins with symptoms that send most people to the doctor: a fluid buildup around the lungs (pleural effusions), shortness of breath, pain in the chest, or pain or swelling in the abdomen. The doctor may order an X-ray or CT scan of the chest or abdomen. If further examination is warranted, the following tests may be done:

What is the prognosis for mesothelioma?

Like most cancers, the prognosis for this disease often depends on how early it is diagnosed and how aggressively it is treated. Unfortunately, oftentimes health care professionals find mesothelioma at a stage in which a cure is unobtainable. Many will succumb to the disease within one year of diagnosis.

Treatment options are determined by the stage of mesothelioma (the extent to which the tumor has spread in the body). There are three staging systems currently in use, and each one measures somewhat different variables.

The oldest staging system and the one most often used is the Butchart system, based mainly on the extent of primary tumor mass and divides mesotheliomas into four stages.

The more recent TNM system considers variables of tumor in mass and spread, lymph node involvement, and metastasis.

TNM system: variables of T (tumor), N (lymph nodes), and M (metastasis)

The Brigham system is the latest system and stages mesothelioma according to resectability (the ability to remove the tumor surgically) and lymph node involvement.

What is the treatment for mesothelioma?

There are three traditional kinds of treatment for patients with malignant mesothelioma. Often physicians combine two or more of these in the course of treatment:

Surgery: There are several types of surgery used in treating mesothelioma.

Radiation therapy uses high-energy X-rays to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external radiation therapy) or from putting materials that produce radiation (radioisotopes) through thin plastic tubes in the area where the cancer cells are (internal radiation therapy).

If fluid has collected in the chest or abdomen, your doctor may drain the fluid out of your body by putting in a needle into the chest or abdomen and using gentle suction to remove the fluid. If a doctor removes fluid from the chest, this is called thoracentesis. If a physician removes fluid from the abdomen, this is called paracentesis. Your doctor may also put drugs through a tube into the chest to prevent more fluid from accumulating.

Health care professionals administer adjuvant radiation in a manner to avoid exposure of the opposite lung to radiation and its potential side effects.

Chemotherapy is the use of drugs to kill cancer cells. Health care professionals administer chemotherapy by pill, or it may be put into the body by a needle in the vein or muscle. Often, a platinum-based chemotherapy (cisplatin or carboplatin) drug is given along with a second agent, pemetrexed. The side effects can be quite toxic, therefore they are used in people who are physically well enough to tolerate these side effects.

Chemotherapeutic agents can be administered either systemically (through the bloodstream) or intrapleurally (in the pleural cavity). When it is administered intrapleurally, the treatment is localized at the site of the tumor. These drugs are generally very toxic and you should discuss their use very carefully with your physician.

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Is there any promising research or are there promising drugs for mesothelioma?

Medical researchers are testing new approaches to treat malignant mesothelioma. They often combine traditional treatments or include something entirely new. They include:

Research is being conducted at various cancer centers all over the United States.

A recent study involving L-NDDP produced two cases of remission in mesothelioma patients. Another study found that a drug known as lovastatin might hold promise for mesothelioma patients.

To learn more about mesothelioma clinical studies and journal medical journal articles, visit the Mesothelioma Web (http://www.mesotheliomaweb.org).

What other kinds of information is available for people with mesothelioma?

There are numerous cancer web sites, some specific to mesothelioma. Because they are often difficult to locate, we have listed some relevant medical web sites that have information about mesothelioma.

American Institute for Cancer Research(http://www.aicr.org)

American Thoracic Society(http://www.thoracic.org/)

Canadian Cancer Society(http://www.bc.cancer.ca)

Mesothelioma Web(http://www.mesotheliomaweb.org)

Medically Reviewed on 7/5/2018

References

Mujoomdar, A.A., and D.J. Sugarbaker. "Hyperthermic Chemoperfusion for the Treatment of Malignant Pleural Mesothelioma." Semin Thorac Cardiovasc Surg 20.4 Winter 2008: 298-304.

Ried, Michael, et al. "Cytoreductive surgery and hyperthermic intrathoracic chemotherapy perfusion for malignant pleural tumours: perioperative management and clinical experience." Eur J Cardio-thoracic Surgery 43.4 April 2013: 801-807.

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Mesothelioma Causes, Symptoms, Treatment & Prognosis

Mesothelioma: How Has Paul Kraus Survived For Over 20 Years?

Looking for mesothelioma information? The following section provides extensive information about mesothelioma, including symptoms, treatment, and more. Click on an item in the menu below to jump to that topic:

Mesothelioma is a rare form of cancer. It comes from cells of the mesothelium that covers many internal organs. There are about 2,000 cases of mesothelioma diagnosed in the United States each year. Mesothelioma comes from exposure to asbestos. Asbestos is a cancer causing material used in many different kinds of products. Many companies kept using it even after they knew that it was dangerous.

Although rare, mesothelioma cancer is not a death sentence. The longest-living mesothelioma survivor in the world wrote a free book about it.

Mesothelioma is a rare form of cancer. It is sometimes called asbestos cancer. It comes from cells of the mesothelium, the lining that covers many of the internal organs.

The main purpose of the mesothelium is to make the fluid between tissues and organs. This fluid provides a slippery and protective surface to allow movement.

The fluid allows the lungs to expand and contract inside the body each time you take a breath. When the cells of the mesothelium turn cancerous they become mesothelioma. That is where the name comes from.

Mesothelioma is a rare disease. There are only approximately 2,000 cases diagnosed in the United States every year. Many more cases occur around the world. It is most common in Australia and the U.K. where they used large amounts of asbestos.

Number of cases per year in other countries:

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There are four types of malignant mesothelioma: Pleural, peritoneal, pericardial and testicular. Pleural mesothelioma affects the outer lining of the lungs and chest wall. It represents about 75% of all cases. Peritoneal mesothelioma affects the abdomen and represents about 23%. Incidences of cases in the lining of the testis and the heart represent about 1% each.

When then pleural lining around the lungs and chest wall are involved in this cancer it is called pleural mesothelioma. There are actually two layers of tissue that comprise the pleural lining. The outer layer, the parietal pleura, lines the entire inside of the chest cavity. The inner layer is called the visceral pleura and it covers the lungs.

Mesothelioma usually affects both layers of the pleura. Often it forms in one layer of the pleura and invades the other layer. The cancer may form many small tumors throughout this tissue.

Learn More About Pleural Mesothelioma

When the peritoneum, the protective membrane that surrounds the abdomen is involved in this cancer it is called peritoneal mesothelioma. Just like pleural mesothelioma, there are two layers of tissues involved with the peritoneum, the parietal layer covers the abdominal cavity, while the visceral layer surrounds the stomach, liver and other organs.

The cancer often forms many small tumors throughout the tissue. One doctor has described it as if someone took a pepper shaker and scattered the pepper over the tissue.

Learn More About Peritoneal Mesothelioma

In addition to the different types of locations within the body, there are also different cell types. These types are all considered mesothelioma, but they can affect the patients prognosis.

The three mesothelioma cell types are: epithelioid, sarcomatoid and biphasic.

Epithelioid mesothelioma cells are the most common type of mesothelioma cell and has the best prognosis of the three cell types. Notice the dark purple, elongated egg shaped cells amongst the healthy pink colored tissue.

Sarcomatoid mesothelioma cells are the rarest of the three cell types and tends to be more aggressive than epitheloid cells. Notice the dark purple nodules amongst the healthy light purple colored tissue.

Biphasic mesothelioma cells are mixtures of both cell types (epithelioid and sacromatoid) and usually has a prognosis that reflects the dominant cell type.

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Mesothelioma is caused by exposure to asbestos and it is therefore considered the asbestos caused cancer.

Asbestos has been in use since ancient times, but after the Industrial Revolution its use became widespread and was used all over the world in thousands of industrial and consumer products even after many companies knew that it was dangerous. Construction materials, automotive parts and household products such as hair dryers and oven mitts contained asbestos in the past.

Today, asbestos has been outlawed in most places around the world, however, asbestos has not been outlawed in the United States and is still found in millions of homes and public buildings, such as schools, offices and parking garages.

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Asbestos is actually a naturally occurring mineral found throughout the world. It was called the magic mineral because it is resistant to heat and corrosion. Also, it is a fiber so it can be woven into other materials.

Asbestos is composed of millions of sharp microscopic fibers. These fibers are so small that the body has difficulty filtering them out. This means that if you around airborne asbestos you may inhale it or ingest it. This is known as asbestos exposure.

The actual process as to how asbestos causes mesothelioma is still being investigated. Most scientists believe that when the small sharp fibers are ingested or inhaled they cause cell damage which can cause chronic inflammation.

This inflammation can then set the stage for disease after many years or even decades. Some scientists believe that a persons immune system may actually help prevent the cancer, even if that person is exposed to asbestos.

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Since asbestos causes this rare disease, how to people get exposed to asbestos? While asbestos was in thousands of products, workers in some professions had more exposure to this carcinogen than others.

Examples of occupations that exposed workers to asbestos includes: Navy veterans, construction trades such as electricians, mechanics, and plumbers, people working in power houses and power plants, firefighters, and refinery workers. Individuals in these professions often had a multitude of asbestos containing products on their various job sites.

Most asbestos containing products were removed voluntarily by the late 1970s. However, because there is no comprehensive ban on asbestos in the U.S. and because of the long latency period, people are still being diagnosed with mesothelioma today.

Learn More About Occupational Asbestos Exposure

The history of asbestos in the United States and other industrialized countries is a sad story of corporate greed. Companies that produced asbestos containing products saw their workers becoming sick with lung scarring, asbestosis, and cancer nearly 100 years ago.

Some companies even brought in researchers and scientists to better understand the health impact of asbestos. Once it was shown that their magic mineral was toxic to human beings, the industry faced a dilemma.

Should they protect workers, warn consumers, notify public health officials, and most importantly, phase out this dangerous mineral? Their answer was no.

Instead industry did just the opposite. They warned no one, kept their knowledge about asbestos secret and continued to use it for decades! Only by the 1960s did independent researchers like Dr. Irving Selikoff of Mt. Sinai School of Medicinebegin to connect asbestos exposure to disease.

By then hundreds of thousands of men, women, and children were already exposed to this deadly mineral. The EPA would ban asbestos in 1989. However, the asbestos industry would sue the EPA and win.

In 1991 the ban was lifted. Even today, there is no comprehensive asbestos ban in the United States. Sad but true.

(Asbestos Medical and Legal Aspects by Barry Castleman)

People exposed directly to asbestos are called primary exposed. Sometimes the person who is primary exposed will transfer asbestos fibers from their clothes to the clothes of another person. The person who gets this transfer of asbestos exposure is said to have secondary exposure.

One example of secondary exposure is called the deadly hug. Sadly, the deadly hug happens when an adult comes home from work with asbestos on their clothes and hugs their son or daughter, unknowingly transferring the dangerous fibers to their child. There have been many cases of adults being diagnosed with mesothelioma whose only exposure to asbestos came from their time as a child.

Read About Secondary Exposure

There is a long latency period for mesothelioma which is the time from asbestos exposure to diagnosis of the cancer. This period can range anywhere from 20 to 50 years. There are different theories as to why there is such a long latency period and why most people exposed to asbestos do not get mesothelioma.

One theory suggests that there may be other variables that play a role. For example, some doctors believe that the condition or competency of a persons immune system could determine whether asbestos in their body leads to cancer.

Other possibilities include a persons genes and diet.

When doctors suspect a patient has mesothelioma they will initiate a work-upin order to make a diagnosis. This work-up may include imaging scans, biopsies, pathology exams, blood tests and staging.

Diagnosing Mesothelioma

Various types of scans may be used to determine if there are signs of tumors or other abnormalities. These scans may include X-rays, CT scans, MRIs, or PET scans.

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If scans reveal what doctors believe may be a cancer then a biopsy may be suggested. A biopsy is a procedure where doctors remove a small piece of the suspected tumor tissue from the patients body.

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Blood tests and biomarkers may sometimes be used to determine if mesothelioma is present in the body. While these tests are helpful they are not considered as important as the biopsy which is considered the gold standard.

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The biopsy material will then be given to a pathologist. A pathologist will use special stains and other tests to determine if there is cancer and identify exactly what type of cancer was removed from the patient.

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If mesothelioma is diagnosed, doctors may stage the disease. Over the years a variety of staging systems have been used. The one used most frequently today groups the disease into localized (only in the mesothelium) or advanced (spread outside the mesothelium).

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The prognosis of mesothelioma or any other cancer depends on a number of variables. Those variables include:

More on Prognosis

A doctor specializing in mesothelioma can properly diagnose you and determine the best course of treatment. Find a mesothelioma specialist or doctor near you.

The treatments for mesothelioma can be divided into three paths: Conventional Therapies, Clinical Trials, and Alternative Modalities.

Conventional therapies include chemotherapy, radiation therapy and surgery. The standard chemo drugs used are Alimta (pemetrexed) and cisplatin (or carboplatin). They are often prescribed for the various types of mesothelioma, regardless of location. Both chemo and radiation therapy are known as cytotoxic or cell killing therapies. They work indiscriminately, killing both healthy and cancer cells. This is the reason that they can have severe side effects.

Learn About Treatment

The standard of care in many hospitals is to treat peritoneal mesothelioma with surgery and HIPEC. HIPEC stands for hyperthermic intraperitoneal perioperative chemotherapy which basically means flushing the surgical area with heated chemotherapy during the surgical procedure. The obvious advantage of this approach is that it enables doctors to put the chemo in exactly the place it needs to be.

Of all the conventional treatments available, surgery is generally considered the most effective. For pleural mesothelioma, there are various types of surgical procedures, including lung sparring surgery (also called pleurectomy/decorticiaton or PD) and extrapleural pneumonectomy (also called EPP).

Pleurectomy/decortication surgery is a two-part surgery that removes the lining surrounding one lung (pleurectomy), then removes any visible cancer seen growing inside the chest cavity (decortication). The advantage of P/D or lung sparring surgery is exactly what the name implies a lung is not removed.

An extrapleural pneumonectomy (EPP) is a much more invasive surgery than PD. An EPP involves removing a lung, the diaphragm, portions of the chest lining and heart lining, and nearby lymph nodes.

Numerous studies have been performed comparing the prognosis with a pleurectomy/decortications surgery versus an extrapleural pneumonectomy. While there is no consensus on the subject, the latest reports suggest that PD may be a better choice for many patients because survival is generally equivalent to EPP and PD is less invasive and therefore easier to tolerate.

There are also other surgical procedures used to treat pleural effusion. Pleural effusion is the buildup of excess fluid in the pleural space between the visceral and parietal linings of the lungs. Examples of these procedures include pleurodesis and thoracentesis.

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Clinical trials are treatments that are still being tested. These treatments may include chemotherapy or other more innovative approaches based on immune therapy, gene therapy or other biological approaches. One example of new treatments being tried in mesothelioma involve the use of monoclonal antibodies. Monoclonal antibodies are essentially an immune system therapy that tries to use antibodies to target cancer cells. The National Cancer Institute indexes clinical trials offered throughout the country.

Discover Clinical Trials

Alternative modalities include a large number of approaches such as intravenous vitamin therapy, herbs and Traditional Chinese Medicine, cannabis oil, dietary approaches, and mind-body medicine. It is important to note that while none of these modalities are FDA approved, there are a number of long-term mesothelioma survivors who have used them, including Paul Kraus.

Read About Alternative Treatments

Mesothelioma is not the only disease caused by asbestos. Asbestosis which is essentially scarred lung tissue, pleural plaques and some lung cancers can also be caused by asbestos. There may also be compensation available to victims of these diseases as well. Treatments vary by condition.

Learn About Other Asbestos Diseases

Curcumin is a natural occurring phytochemical found in turmeric, which is an Indian spice that gives curry powder its characteristic golden color. A study published by Jill M. Miller in Cancer Prevention Research suggest that curcumin can attach malignant mesothelioma cells in two ways. First, curcumin was able to induce pyroptosis, a highly inflammatory form of programmed cell death, in human malignant mesothelioma cells. In addition, curcumin was shown to protect against inflammation, which is a key mediator in the development of malignant mesothelioma and may be a key contributor to the dismal prognosis associated with the condition. Consequently, consumption of curcumin can offer a two-pronged attack against malignant mesothelioma by inducing pyroptosis in malignant mesothelioma cells as well as protecting against inflammation.

Nutritional status may also play a role in mesothelioma prognosis. The Controlling Nutritional Status (CONUT) score was developed as a screening tool for early detection of poor nutritional status. A recent study published in a medical journal suggests that mesothelioma patients who were well nourished and had a CONUT score 2, had greater overall survival rates than those who were nutritionally challenged, CONUT score 3.

Treatments for mesothelioma can alter the appetite either because people are physically unable to eat properly due to the cancer or the treatment such as chemo, or because the taste of food is altered. Regardless, adequate nutrition is paramount for people with mesothelioma because patients often lose essential muscle and weight after diagnosis which can dramatically impact their prognosis. Consequently, eating a well-balanced diet can help people feel better when undergoing treatment for malignant mesothelioma.

Therefore, screening for nutritional status prior to treatment, consuming some dietary phytochemicals, as well as eating an overall well-balanced diet should help improve the outcome and overall state of well-being for patients undergoing treatment for malignant mesothelioma.

More:

Mesothelioma: How Has Paul Kraus Survived For Over 20 Years?

mesothelioma | Definition, Symptoms, Diagnosis, & Treatment | Britannica

Mesothelioma, tumour that arises from the sheet of cells known as the mesothelium, which lines body cavities and forms the tissue layers referred to as the pleura and the peritoneum. The pleura is located in the chest cavity, either lining the chest wall (parietal pleura) or covering the lung (visceral pleura), and the peritoneum is the corresponding tissue in the abdomen. Roughly 75 percent of mesothelioma cases originate in the chest. Mesothelial cells can also be found in other areas of the body, such as the scrotal sac and the pericardium (the sac surrounding the heart), and in rare cases the tumour may arise primarily in those locations.

Some 2,000 to 3,000 cases of mesothelioma are diagnosed annually in the United States and more elsewhere around the world, related in part to asbestos exposure rates. For males born between 1945 and 1950 in western Europe, researchers projected that mesothelioma during the period from 1995 to 2029 would reach rates as high as 1 in 150 because of asbestos exposure in this population.

There is an unequivocal association with asbestos exposure in about 80 percent of cases. The latency period between exposure and the development of disease typically ranges from 20 to 50 years, with an average of about 30 years. Other causative agents, such as SV40 (simian virus 40), have been postulated; however, data are inconclusive. Some cases are idiopathic, in which no known cause can be identified. Use of asbestos was strictly regulated in the United States beginning in the latter part of the 20th century, though it is still used in the developing world. Erionite, which is similar to asbestos, is found in the soil in Turkey and is associated with concomitant pockets of high mesothelioma incidence. The biology of asbestos exposure and subsequent development of cancer is not clearly understood, because of the long latency period. However, a chronic inflammatory reaction, causing DNA damage to the mesothelial cells, is likely involved. Unlike lung cancer, the eventual development of mesothelioma is not associated with smoking.

The diagnosis of mesothelioma usually occurs at advanced stages, because the thin layer of tumour that develops may not be discernible in X-rays, nor may it lead to symptoms. The most common complication leading to an eventual diagnosis is pleural effusion (a collection of fluid around the lung in the pleural space), whereby a person becomes short of breath. Pain is common with more-advanced disease, when the tumour invades the ribs and muscles of the chest wall. The use of computed tomography (CT; computerized axial tomography) is essential to determine the extent of disease and the stage of tumour development. CT scanning is also used to determine whether the patient might be considered a candidate for surgery. Positron emission tomography (PET) is useful to assist in the determination of metastasis (spread) to other areas of the chest or body. Serum biomarkers, such as mesothelin, osteopontin, and megakaryocyte potentiating factor, have shown some promise for the development of blood tests to screen for the disease, as well as for following patients for evidence of recurrence after treatment.

There are many subtypes of mesothelioma, based on microscopic pathologic examination. The most common subtype is epithelial mesothelioma, followed by biphasic, or mixed, disease, which has epithelial and sarcomatous (connective tissue) involvement; less common is the solely sarcomatoid subtype. The pathologic diagnosis of mesothelioma, using microscopic techniques, can be difficult and often requires that a battery of immunohistochemistry (IHC) tests be performed on each tumour to determine whether it is mesothelioma or perhaps another type of tumour that has spread to the thoracic or abdominal cavity. IHC uses colorimetric antibodies directed at proteins on the surfaces of cells. A pattern of both positive and negative staining is interpreted by the pathologist. Some of the more common positive-staining antibodies that are used include WT1 (Wilms tumour 1) and mesothelin and cytokeratin 5/6. Commonly used negative-staining epithelial antibodies include CEA (carcinoembryonic antigen), LeuM1, and TTF-1 (thyroid transcription factor 1).

Reported survival for patients with mesothelioma has been relatively poor, ranging in most cases from 9 to 18 months with or without treatment. Factors used to predict survival include epithelial subtype, involvement of regional (mediastinal) lymph nodes, and size of the tumour. The ability to completely remove the tumour at surgery and the use of multimodality (surgery, chemotherapy, and radiation therapy) in some combination-therapy approaches can also influence survival.

Advances in multimodality therapy have included the use of a class of chemotherapy drugs referred to as folate antimetabolites. The most common drug used in this class is pemetrexed, which is most effective when combined with platinum-based agents, such as cisplatinum. These drugs may be given as definitive treatment to patients that are not surgical candidates, and up to 50 percent of treated individuals may respond with tumour arrest and shrinkage and modestly improved survival. Clinical trials have evaluated the use of these drugs prior to surgery (neoadjuvant therapy). The weight of evidence indicates that surgical removal of the tumour is important for improved survival, but only if surgery is included with other therapies. Care must be taken when determining whether a patient should undergo surgery, since many patients are at advanced age.

Removal of the tumour alone from the surfaces on which it is growing (a procedure known as pleurectomy) may be best in early-stage patients. A more aggressive operation, extrapleural pneumonectomy (EPP), may be required in more-advanced cases. EPP involves the removal of tumour, pleura, diaphragm, and pericardium, with reconstruction of the latter two structures. The tumour grows over a very large surface area, and for that reason the risk of local recurrence following surgery is high. Many modalities have been evaluated and are being used for adjuvant (after surgery) treatment, including heated chemotherapy instillation (gradual introduction of liquid drug into cancerous tissue), photodynamic therapy (administration of a drug that becomes active when the cancerous tissue is exposed to a certain form of light), and various forms of radiation therapy. Local control over the administration of therapy can be made more precise by the use of computerized conformal radiation therapy techniques, such as intensity-modulated radiation therapy, in which three-dimensional CT is used to guide the delivery of very precise doses of radiation to the tumour or to parts of the tumour. Tumour-treating field (TTF) therapy, in which an electric field is used to impair tumour cell division, may be given in combination with certain chemotherapeutic agents to combat malignant pleural mesothelioma.

A number of experimental approaches to treatment capitalizing on the presence of biological or molecular targets have been attempted. Some promising future targets identified in clinical studies have included proteins (e.g., mesothelin) that are commonly found on mesothelioma cells. Growth factors, antiangiogenic drugs, which block the growth of tumour blood vessels, and molecules that stimulate programmed cell death (apoptosis) have also been investigated.

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mesothelioma | Definition, Symptoms, Diagnosis, & Treatment | Britannica

What to Avoid Saying to Someone with Mesothelioma – Asbestos.com

When you are diagnosed with cancer, people often think youre going to die, especially with an aggressive disease such as mesothelioma.

And if you outlive their expectations, you must not be as sick as you led on.

As time goes by, people tend to forget about your health issues, especially if the reminders arent apparent.

You stop seeing the looks, hearing the concerned questions or receiving the special treatment.

As a seven-year survivor, its interesting looking back on how conversations about my cancer have changed among friends and family.

Its an important lesson to anyone who may interact with a cancer survivor this holiday season, whether theyre newly diagnosed or several years into survival.

Knowing what to say and what to avoid saying can strengthen relationships and get positive results out of these interactions.

The longer you are around, the more people seem to forget something is wrong with you. Its out of sight, out of mind.

I dont necessarily have a problem with that. I dont want to be treated differently because I have cancer.

But youll also hear comments like, I thought you were cured or You dont look sick. People sometimes wonder why I still go to Boston. Theyre surprised to find out Im still having treatment seven years later.

There is no cure for mesothelioma. I have beaten the odds in my survival, but Im aware the cancer can come back fast and aggressive at any moment.

I feel no one is truly cured of cancer. You always need to be aware that either the same cancer or a different cancer can come back, whether its been seven years or 50 years.

Another thing people should avoid is to not take a cancer survivors word as truth. Just because I outlived the expectations of my doctors doesnt mean I was lying about the state of my condition.

I think this may happen more often with a rare cancer such as mesothelioma because most people dont know much about it.

Our monthly online support group helps patients and families cope with the effects of mesothelioma.

I try my best to not get caught up in the past. I dont see the point of thinking about what-if scenarios.

Whats done is done.

I realize that mesothelioma is unlike many cancers because the primary cause is well known: Exposure to asbestos.

This prompts others to wonder how someone like me a registered nurse of 43 years was diagnosed with a cancer commonly associated with Navy veterans and construction workers.

I dont fit the typical patient profile, yet here we are. I havent dwelled on it, so I dont expect others to.

Asking how or why this happened to me wont change anything. I prefer that people focus on my future rather than my past.

I live in a small town in Maine. It took three months for doctors here to finally get to the bottom of my condition.

Biopsy samples were sent to Massachusetts General Hospital in Boston. My diagnosis was then confirmed at Brigham and Womens Hospital, where I underwent aggressive surgery to remove as much cancerous growth from my chest as possible.

I continue to visit Boston every three weeks, receiving immunotherapy infusions at Dana-Farber Cancer Institute.

Sometimes people here wonder why I make the four-hour, round-trip drive to Boston rather than go to our local hospital or the cancer center in Portland, Maine, less than an hour away.

The answer is simple: I feel more comfortable in Boston under the care of mesothelioma specialists.

When any of the hospitals in Maine get a pulmonary oncologist who trained at Brigham, Dana-Farber or any other mesothelioma specialty center, Ill be fine staying closer to home.

Until then, I will continue my care where the research is being done.

Its not that I think Im too good for our local doctors. I just want to make the best decisions for my health. That means traveling to a specialty center with the latest technologies and a team of experts.

Its perhaps the worst thing you could ask someone battling cancer.

While extremely personal and invasive, its also impossible to answer. Like everyone else, I dont know how long Ill be on this earth. I also dont know if it will be the mesothelioma that kills me or something unrelated.

My surgeon, Dr. David Sugarbaker, was good about not estimating length of survival. When something came up, we would address it. My medical oncologist, Dr. David Jackman, is the same way.

I tell everyone that I take it one scan at a time. I get CT scans every three months. Until then, I have nothing new to share.

Asking more specific questions such as How was your last scan? or When is your next scan? is much better than How long do you have?

Knowing what to say to a cancer survivor is equally as important as what not to say.

The advice I would give others is to make sure youre genuine in the questions you ask and the support you offer.

Ive found that most of the people who have offered to help are serious about it. They arent just making the gesture because its the polite or right thing to do.

When Ive had comments made to me about how much I do or give or take care of others, I always say the day will come where I may need them to return the favor.

I usually rely on my brothers to help me more than friends or acquaintances, but its nice to know people care.

And if you are curious about something, dont be afraid to ask.

I recently had someone I work with at our local gym ask me why I go to Boston once a month and if something was wrong. I told her I have cancer, and she had no idea.

Ive known her since Ive had this disease, but I guess it never came up in conversation. She wasnt rude for asking, and I wasnt offended by her question.

Sometimes, the solution to what to say and not to say to someone with cancer is asking in a simple and direct way. The more we talk, the more we find out about each other and can offer support and guidance as we see fit.

Free Mesothelioma ResourcesGet Access to Free Resources for Patients & Loved Ones

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What to Avoid Saying to Someone with Mesothelioma - Asbestos.com


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