Where to Watch and Stream Have a Good Trip: Adventures in Psychedelics Free Online – EpicStream

Cast: Nick OffermanSarah SilvermanAdam ScottRosie PerezAdam Horovitz

Geners: Documentary

Director: Donick Cary

Release Date: May 11, 2020

Celebrities recall their most mind-bending trips via animations, reenactments and more in this comedic documentary exploring the story of psychedelics.

This one's easy. Have a Good Trip: Adventures in Psychedelics is currently available to stream on Netflix. The popular streaming platform is home to many original series as well as classic movies and television shows.In the improbable case that you don't have Netflix, and don't know someone who does, a subscription starts at $9.99.

At the time of writing, Have a Good Trip: Adventures in Psychedelics is not available to stream on Hulu through the traditional account which starts at $6.99.However, if you have the HBO Max extension on your Hulu account, you can watch additional movies and shoes on Hulu. This type of package costs $14.99 per month.

Disney Plus is expanding, but their branding is still quite specific, and Have a Good Trip: Adventures in Psychedelics is currently not available to stream there. With Disney+, you can have a wide range of shows from Marvel, Star Wars, Disney+, Pixar, ESPN, and National Geographic to choose from in the streaming platform for the price of $7.99 monthly or $79.99 annually.

Sorry, Have a Good Trip: Adventures in Psychedelics is not available on HBO Max. There is a lot of content from HBO Max for $14.99 a month, such a subscription is ad-free and it allows you to access all the titles in the library of HBO Max. The streaming platform announced an ad-supported version that costs a lot less at the price of $9.99 per month.

Unfortunately, Have a Good Trip: Adventures in Psychedelics is not available to stream for free on Amazon Prime Video. However, you can choose other shows and movies to watch from there as it has a wide variety of shows and movies that you can choose from for $14.99 a month.

Have a Good Trip: Adventures in Psychedelics is not available to watch on Peacock at the time of writing. Peacock offers a subscription costing $4.99 a month or $49.99 per year for a premium account. As their namesake, the streaming platform is free with content out in the open, however, limited.

Have a Good Trip: Adventures in Psychedelics is not on Paramount Plus. Paramount Plus has two subscription options: the basic version ad-supported Paramount+ Essential service costs $4.99 per month, and an ad-free premium plan for $9.99 per month.

No dice. Have a Good Trip: Adventures in Psychedelics isn't streaming on the Apple TV+ library at this time. You can watch plenty of other top-rated shows and movies like Mythic Quest, Tedd Lasso, and Wolfwalkers for a monthly cost of $4.99 from the Apple TV Plus library.

No luck. Have a Good Trip: Adventures in Psychedelics is not available to watch on Direct TV. If you're interested in other movies and shows, Direct TV still has plenty of other options that may intrigue you.

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Where to Watch and Stream Have a Good Trip: Adventures in Psychedelics Free Online - EpicStream

Postdoctoral Research Fellow in Psychedelics, Neurodevelopment and Electrophysiology job with UNIVERSITY OF SYDNEY | 303322 – Times Higher Education

About the opportunity

The Drug Discovery Initiative and the School of Chemistry is seeking a motivated Postdoctoral Research Fellow with prior experience in behavioural and molecular neuroscience. This exciting opportunity involves investigating how psychedelic molecules impact the neurodevelopment in preclinical models of disease. The successful applicant will work under the supervision of Professor Michael Kassiou, and Dr Eryn Werry from the Drug Discovery Initiative in the School of Chemistry at the University of Sydney.

Your key responsibilities will be to:

The Drug Discovery Initiative aspires to enable improved health outcomes through innovative drug discovery. Its mission is to design and develop innovative tools and techniques for identifying novel therapeutic targets, delivery mechanisms and bioactive molecules with high potential for industry uptake and clinical translation. By providing an overarching framework that links aligned areas of research strength from across the University, the Initiative will accelerate impactful research and enhance multi-disciplinary collaboration both within the University community and with broader health industry partners.

The School of Chemistry at the University of Sydney is a leading Chemistry department in the country, with outstanding staff and students undertaking world-leading teaching and research. With more than 30 academic staff, 100 research staff, and 100 research students we conduct research across the full spectrum of pure and applied chemistry. Our research excellence is recognised by numerous prizes and awards to individual staff members and the award of almost $10 million in research funding each year. With the support of over 30 professional, technical and administrative staff, the School of Chemistry administers and delivers undergraduate teaching for more than 3 000 students. We are committed to creating a diverse workplace by improving equity, access and opportunity, and we are continuously working to identify and remove biases and barriers in an effort to make our workplace open, supportive and safe for everyone.

To learn more about the Drug Discovery Initiative, click here

About you

The University values courage and creativity; openness and engagement; inclusion and diversity; and respect and integrity. As such, we see the importance of recruiting talent aligned to these values and are looking for a

Postdoctoral Research Fellow who has:

Essential Experience:

Preferred Special Knowledge, Skills, and Abilities:

To keep our community safe, please be aware of our COVID safety precautions which form our conditions of entry for all staff, students and visitors coming to campus.

Sponsorship / work rights for Australia

Please note: Visa sponsorship is not available for this position.

Australian Temporary Residents currently employed at the University of Sydney may be considered for a fixed term contract for the length of their visa, depending on the requirements of the hiring area and the position.

Pre-employment checks

Your employment is conditional upon the completion of all role required pre-employment or background checks in terms satisfactory to the University. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, the University may take any necessary step, including the termination of your employment.

EEO statement

At the University of Sydney, our shared values include diversity and inclusion and we strive to be a place where everyone can thrive. We are committed to creating a University community which reflects the wider community that we serve. We deliver on this commitment through our people and culture programs, as well as key strategies to increase participation and support the careers of Aboriginal and Torres Strait Islander People, women, people living with a disability, people from culturally and linguistically diverse backgrounds, and those who identify as LGBTIQ. We welcome applications from candidates from all backgrounds.

How to apply

Applications (including a cover letter, CV, and any additional supporting documentation) can be submitted via the Apply button at the top of the page.

For employees of the University or contingent workers, please login into your Workday account and navigate to the Career icon on your Dashboard. Click on USYD Find Jobs and apply.

For a confidential discussion about the role, or if you require reasonable adjustment or support filling out this application, please contact Helen Efstathiou, Recruitment Consultant. Recruitment Operations, Human Resources on +61 2 8627 7137 or by emailrecruitment.sea@sydney.edu.au

The University of Sydney

The University reserves the right not to proceed with any appointment.

Click to view the Position Description for this role.

Applications Close

Wednesday 17 August 2022 11:59 PM

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Postdoctoral Research Fellow in Psychedelics, Neurodevelopment and Electrophysiology job with UNIVERSITY OF SYDNEY | 303322 - Times Higher Education

Psychedelics – Alcohol and Drug Foundation

Types of psychedelics

Psychedelics have been used since ancient times by various cultures throughout the world for their mystical and spiritual associations. LSD, magic mushrooms, Mescaline and DMT are usually swallowed, smoked or inhaled. Mushrooms are usually eaten fresh, cooked or brewed into a tea.

Occasionally, they may be mixed with tobacco or cannabis and smoked. Mescaline is usually swallowed. Peyote buttons may be ground into a powder and smoked with cannabis or tobacco. The buttons can also be chewed or soaked in water to produce a liquid.

Most forms of NBOMe are inactive if swallowed, and the most common methods of taking them are under the tongue, held in the cheek or snorted.

Generally, people who use psychedelics dont take them on a regular basis, but on occasions that may be weeks or months apart.

There is no safe level of drug use. Use of any drug always carries some risk. Its important to be careful when taking any type of drug.

Psychedelics affect everyone differently, based on:

The effects of psychedelics can last several hours and vary considerably, depending on the specific type of psychedelic. The following may be experienced during this time:

Sometimes you can experience a bad trip, which is frightening and disturbing hallucinations. This can lead to panic and unpredictable behaviour, like running across a road or attempting suicide.

If you take a large amount or have a strong batch, you are likely to experience negative effects of psychedelics.6,7

The most common long-term effect of psychedelic use is the flashback. Flashbacks are a re-experience of the drug and can occur days, weeks, months and even years later.

Flashbacks can be triggered by the use of other drugs or by stress, fatigue or physical exercise. The flashback experience can range from being pleasant to causing severe feelings of anxiety. They are usually visual and last for a minute or two.

The effects of mixing psychedelics with other drugs, including alcohol, prescription medications and over-the-counter medicines, are often unpredictable.

Mixing psychedelics with stimulant drugs increases the stimulant effects and can further increase heart rate and place the body under extreme stress. Stimulants can also increase anxiety which can lead to a negative experience.8

Combing psychedelics with depressant drugs such as alcohol may further reduce coordination and increases the chances of vomiting. Alcohol may also decrease the effects of the psychedelic.8

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Psychedelics - Alcohol and Drug Foundation

Psychedelics in problem-solving experiment – Wikipedia

1966 American study

Psychedelic agents in creative problem-solving experiment was a study designed to evaluate whether the use of a psychedelic substance with supportive setting can lead to improvement of performance in solving professional problems. The altered performance was measured by subjective reports, questionnaires, the obtained solutions for the professional problems and psychometric data using the Purdue Creativity, the Miller Object Visualization, and the Witkins Embedded Figures tests.[1] This experiment was a pilot that was to be followed by control studies as part of exploratory studies on uses for psychedelic drugs, that were interrupted early in 1966 when the Food and Drug Administration declared a moratorium on research with human subjects, as a strategy in combating illicit use.[2]

Some weeks before the actual experiment, a preliminary experiment was conducted. It consisted of two sessions with four participants in each. The groups worked on two problems chosen by the research personnel. The first group consisted of four people with professional experience in electrical engineering, engineering design, engineering management and psychology. They were given 50 micrograms of LSD. The second group consisted of four research engineers, three with a background in electronics and one in mechanics. They were given 100 milligrams of mescaline. Both groups were productive in ideation but, according to Fadiman, the fact that the participants didn't have actual personal stake in the outcome of the session negatively affected the actualization of the ideas. This is why the actual study focused on personal professional problems that the participants were highly motivated to tackle.[3]

Commonly observed characteristics of the psychedelic experience seemed to operate both for and against the hypothesis that the drug session could be used for performance enhancement. The research was therefore planned so as to attempt to provide a setting that would maximize improved functioning, while minimizing effects that might hinder effective functioning.[4]

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Psychedelics in problem-solving experiment - Wikipedia

Mike Tyson Fighting Against The Stigma Surrounding …

MIAMI (CBSMiami) Inside the ring, it seemed like Iron Mike Tyson had steel in his gloves. He became the youngest heavyweight champ ever with 44 of his 58 fights ending by knockout.

He once infamously said, Its just my nature to reach for you and take your heart, your spleen, your blood, and your liver.

But, now, 55, Mike Tyson seems to be all heart. The fighter is now on a mission to provide peace of mind to anyone willing to listen.

My mind was blown away with psychedelics and I just wanted the world to know what I experienced, Tyson told thestanding-room-only crowd at Wonderland Miami, dubbed the largest psychedelic medicine event, ever.

It was attended by scientists and medical professionals from around the globe.

Tyson says he began using psychedelics about five years ago, telling CBS4 News, with pure joy, its changed his life for the better, forever.

Thats psychedelics, baby! Thats the toad, baby. Thats some shrooms, baby, Tyson exclaimed, I took some medicine. The right medicine. It helps me reach the highest potential.

Tyson confessed the toughest opponent he ever faced, inside or outside the ring, was himself. The champ admitting he still battles low self-esteem, even saying he may not have been able to do this interview without the help of psychedelics.

Id probably need a line or something. Id need a line to finish this interview.

Tyson admits he was doing hard drugs like cocaine and was headed down a dark path, much like one of his newest business partners. Oddly enough, another fighter from a different sport.

I was definitely an enforcer. I fought 164 times protecting my teammates, explained Daniel Carcillo, nicknamedCar Bomb for his explosive fighting style. The two-time Stanley Cup winner retired six years ago at 30, left skating on thin ice, physically and mentally, plagued by a laundry list of ailments, including light sensitivity, slurred speech, headache, head pressure, insomnia, impulse control issues, depression, anxiety, suicidal ideation, Carcillo noted.

Scientists and medical professionals say psychedelics re-set the brain, easing and even curing mental health maladies ranging from traumatic brain injury to depression and anxiety.

Dr. Joseph Tucker, the CEOofEnveric Biosciences, explains, These are ways to remake the brain and give the brain new avenues, new ways of thinking or new opportunities. So, thats how you can actually start to re-wire the brain, and thats what the latest science is showing.

Carcillo said he felt like his brain was made brand new after a teammate introduced him to psilocybin, better known as magic mushrooms, two and a half years ago.

Theres no FDA approved pharmaceutical for traumatic brain injury and once I took psilocybin I got clear brain scans, clear blood work. Then, I was able to put this innovation I had into patents and create Wesana Health.

Wesana Health is an integrated life science company on a mission to revolutionize the treatment of neurological health Carcillo brought Mike Tyson on board as an advisor and investor.

Now, theyre both doing what they do best: fighting against the stigma associated with psychedelics, Iwas afraid of psychedelics too and they made me the man I am now, concluded Tyson.

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Mike Tyson Fighting Against The Stigma Surrounding ...

How MDMA and Psilocybin Became Hot … – The New York Times

Even some Republicans, a group that has traditionally opposed the liberalization of drug laws, are starting to come around. Last month, the former Texas governor Rick Perry, citing the high rates of suicide among war veterans, called on his states legislators to support a Democratic-sponsored bill that would establish a psilocybin study for patients with PTSD.

Weve had 50 years of government propaganda around these substances, and thanks to the research and a grass-roots movement, that narrative is changing, said Kevin Matthews, a psilocybin advocate who led Denvers successful ballot measure.

Long before Nancy Reagan warned the nation to just say no to drugs and President Richard Nixon supposedly pronounced Timothy Leary the most dangerous man in America, researchers like William A. Richards were using psychedelics to help alcoholics go dry and cancer patients cope with end-of-life anxiety.

The drugs were legal, and Dr. Richards, then a psychologist at the Maryland Psychiatric Research Center, was among scores of scientists studying the therapeutic prowess of entheogens, the class of psychoactive substances that humans have used for millenniums. Even years later, Dr. Richards and other researchers say, many early volunteers called the psychedelic sessions the most important and meaningful experiences of their lives.

But as the drugs left the lab in the 1960s and were embraced by the counterculture movement, the countrys political establishment reacted with alarm. By the time the Drug Enforcement Administration issued its emergency ban on MDMA in 1985, funding for psychedelic research had largely disappeared.

We were learning so much, and then it all came to an end, said Dr. Richards, 80, and now a researcher at Johns Hopkins University School of Medicine.

These days, the Center for Psychedelic and Consciousness Research at Johns Hopkins, created two years ago with $17 million in private funding, is studying, among other things, psilocybin for smoking cessation and the treatment of depression associated with Alzheimers as well as more spiritual explorations involving religious clergy.

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How MDMA and Psilocybin Became Hot ... - The New York Times

This isnt the 60s again: psychedelics business takes off amid culture clash – The Guardian

The Wonderland psychedelic business conference, held recently in Miami, Florida, drew large crowds and big-name keynote speakers such as former heavyweight boxing champion Mike Tyson with the promise of a booming new sector. It is being suggested that the next big development in mental healthcare will come in the form of psychedelic drugs: substances such as psilocybin (magic mushrooms), ayahuasca (a plant-based mixture from South America), and DMT (a naturally occurring hallucinogenic).

While these substances have been illegal and primarily associated with countercultures such as the hippies of the 1960s and ravers of the 1990s, changes in laws and scientific breakthroughs in psychedelic treatments for depression and anxiety have created a new industry projected to be worth 8bn by 2027.

Much as happened with the cannabis industry a decade ago, a culture clash is now developing between social justice activists who fought for the legalisation of psychedelics and wealthy white men, often new to the drugs, who have the resources to dominate an emerging industry.

Two years ago in the US, the city of Denver voted to decriminalise psilocybin mushrooms. It was quickly followed by Oakland and Santa Cruz in California, the state of Oregon, and then Seattle, which added ayahuasca, ibogaine and non-peyote-derived mescaline to the list. Some of these campaigns enjoyed financial support from large companies such as the organic soap producer Dr Bronners.

Celebrities including actors Megan Fox, Will Smith and Jada Pinkett-Smith and talk show host Chelsea Handler have testified to the psychologically transformative powers of a psychedelic trip. As the buzz around these drugs heralds a new industry, will those profiting maintain the countercultural ideals of the people who popularised the drugs?

This isnt the 1960s all over again, the former chief executive of MindMed, JR Rahn, told Forbes as his company was attempting to get approval from the FDA, the US regulator, for its specific types of LSD to treat anxiety. I want nothing to do with those kinds of folks who want to decriminalise psychedelics.

Much of the effort to legalise such substances is centred on offsetting the damage that the war on drugs has caused in impoverished communities often by promising people of colour an economic path into this new, lucrative industry. However, for many of the early investors in psychedelics who are able carry the legalisation baton to the finishing line, the strategy is often to craft a limited version of the industry that places them exclusively in charge.

The idea that psychedelics should only be used to heal something that is broken within you rather than as a way to communally understand our world is the narrow definition that will get FDA approval, says Jason Ortiz, co-founder of the Minority Cannabis Business Association, and executive director of Students For Sensible Drug Policy. That communal bonding will be lost if were only pressing it into pills.

Ortiz fears that if psychedelics fall exclusively into the hands of big pharma, plants often deemed sacred by Native Americans and the surely lucrative industry awaiting them will follow the same path as the legal marijuana industry. Legalisation here has seen the rich get richer, while minorities and psychedelic pioneers were left out in the cold.

Theres an institutionalisation of psychedelic drugs happening that will make them less accessible to the common person, Ortiz says. A lot of these corporations come from big pharma and have established networks within the FDA. Movements for justice threaten that monopoly by saying that folks should be able to cultivate, sell and consume these substances on their own.

Ortiz is pursuing decriminalisation for all psychedelics, allowing individuals to make their own choices about whether and how to take them. He views the pharmaceuticals industry as a threat to that.

However, the chief executive of Enveric Biosciences in Florida, Joseph Tucker, says that to do it the pharma way will simply provide users with more confidence, a better experience and fewer side effects. He points to the synthesis of willow bark into aspirin in the 19th century turning a traditional cure into a more effective, less toxic medicine.

Enveric is creating psychedelic-derived molecules and synthetic cannabinoids for the treatment of mental health disorders, and is currently pursuing FDA approval for its products.

With psilocybin, there can be cardiotoxic effects if its taken every day, and theres also serotonin syndrome [caused by excessive levels of the neurotransmitter in the body], Tucker says. But the biggest issues are with the trip itself. Bad trips rely on three major variables: dose, [mind]set and setting. So people try to really control the mindset and setting, and that constrains how youre able to utilise those therapeutics. In many clinical trials, 90% of patients are screened out for having the wrong mindset, and so it wont work for them.

Tucker points to ketamine an anaesthetic that is often erroneously characterised as a psychedelic because of its history as a club drug as an example of a drug with psychedelic effects that has been shown to be effective in mental health treatments, independent of therapy.

Ketamines approval for off-label use, and its proven efficacy in treating depression and anxiety, has led to a number of clinics popping up across the US where those suffering can legally access it in a medically supervised environment.

Elsewhere, the head of Los Angeles-based Irwin Naturals, Klee Irwin, says: What Ive done for 27 years is collect the best of whats around and put it together into something accessible for all people. So Ill take what indigenous people have discovered through some herbal concoction, and Ill take it and put it into a bottle that you can get at Walmart.

As a publicly traded company and health supplement supplier for big US names such as Costco, Walgreens, CVS and Walmart, Irwin Naturals certainly has the track record to commercialise and legitimise psychedelics. In 2018, Irwin had to convince his more conservative investors that cannabis-derived CBD products were a smart, and not too risky, endeavour: he was proved right when the company became one of the largest CBD wholesalers in the nation.

Before the Wonderland conference, Irwin made headlines by announcing that his company would be entering the markets for psychedelics and THC, the psychoactive component of cannabis.

I wouldnt have been able to do this two years ago: it wouldve been too scary, Irwin says. But right now theres this perfect quiet before the storm an opportunity for us to slip in [to the psychedelics industry] as the first truly household-name brand, which can be viewed publicly as a validation of plant medicine. Soon it will be far less demonised and therell be a whole bunch of people dogpiling in just to make money.

Irwin distinguishes himself from those motivated exclusively by profit by his intention to keep prices low and thereby make the products accessible to all income groups. In this way, he feels the necessary social justice goals can be achieved via big business.

When we started selling CBD, we collapsed the pricing floor by selling it at half the price per milligram of the lowest-priced producer, he says. Since we are the largest, we can bully our competitors to chase us to the floor in terms of pricing, and we are about to do the same thing with marijuana.

Irwin sees the mental health crisis in America as an emergency that warrants an FDA fast-track for psychedelic drug approval as was achieved with Covid vaccines. And he believes companies with the power to drive the prices down should do so as a public good. There are around 600 ketamine clinics in the US, and theyre all mom-and-pop-owned, like video stores before Blockbuster, Irwin says. What we want to do is acquire some of them, and open up some new ones.

For psychedelics such as psilocybin and ayahuasca, which are not approved in America, Irwin is opening retreats in nearby countries such as Costa Rica and Jamaica, preparing his company for what he sees as inevitable drug-law shifts in the US.

Ortiz of the Minority Cannabis Business Association says that, on the whole, large investments in the psychedelic industry are not inherently a bad thing so long as people of all levels of privilege have access to the substances, and the chance to enter the industry. That will help dissolve the stigma around these substances, and there will be countless people who have their mental health issues addressed, and thats a good thing for society in general. That being said, its important that its not solely owned by anyone.

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This isnt the 60s again: psychedelics business takes off amid culture clash - The Guardian

Trip to Sustainability? This Company Is Developing Synthetic Psychedelics To Attempt to Fight Mental Illn – Benzinga

Photo by Raimond Klavins on Unsplash

The following post was written and/or published as a collaboration between Benzingas in-house sponsored content team and a financial partner of Benzinga.

Researchers have long experimented with hallucinogenic drugs for the treatment of mental illness.

While many people may be familiar with psychedelic drug advocate Timothy Learys experiments with LSD or the known effects of magic mushrooms, what they may not know is that there are a variety of hallucinogens that scientists are studying today in the hopes they will be able to treat addiction and mental illness.

Reportedly among the most promising drugs being studied today is ibogaine, a naturally occurring psychedelic substance derived from the bark and roots of the West African shrub Tabernanthe iboga.

Ibogaine has the potential to treat mental health issues like addiction, depression, and anxiety, but a lack of resources is preventing the research and clinical trials from bringing ibogaine treatment to the United States and Canada.

The legal status of ibogaine varies around the globe. Its illegal in ten countries, including the United States and nine European countries. Its regulated in three countries Australia, Israel, and Canada. Countries that have deemed it legal as a prescription pharmaceutical substance include New Zealand, South Africa, and Brazil.

As the substance becomes more widely known as a potentially effective treatment for addiction and mental illness, demand for the natural resource could lead to its depletion. Lack of sustainability is one reason ibogaine hasnt entered mainstream treatment for the conditions its believed to help with. The iboga shrubs root bark contains the highest concentration of ibogaine, and while its possible to harvest the root bark without killing the plant, the method used results in slower growth.

Thats why Mind Cure Health Inc. (CSE:MCUR) has created a synthetic version of the drug that will enable researchers to continue their work without killing the shrubs. MINDCURE, a Vancouver, British Columbia-based life sciences company focused on innovating and commercializing new ways to promote healing and improve mental health, has successfully synthesized ibogaine. The company will be entering pre-clinical trials in Q1 2022 to see if the efficacy of the synthetic version is the same as the semi-synthesized molecule that is currently being used for research purposes.

Earlier this year, MINDCURE announced The Ibogaine Project, a research and development program for manufacturing synthetic ibogaine and conducting preclinical explorations. By manufacturing pharmaceutical-grade ibogaine, MINDCURE wants to provide researchers and clinicians with a sustainable, reliable and regulated supply of the compound to conduct studies and improve knowledge about its potential benefits.

Only a handful of companies are directly working with psychedelics to help solve addiction and mental health issues. Atai Life Sciences (NASDAQ:ATAI) is developing several drugs based on psychedelic substances, including ibogaine and ketamine, and Mind Medicine (NASDAQ:MNMD) is developing 3 clinical-stage programs, 2 of which focus on LSD and the 3rd on ibogaine.

The preceding post was written and/or published as a collaboration between Benzingas in-house sponsored content team and a financial partner of Benzinga. Although the piece is not and should not be construed as editorial content, the sponsored content team works to ensure that any and all information contained within is true and accurate to the best of their knowledge and research. This content is for informational purposes only and not intended to be investing advice.

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Trip to Sustainability? This Company Is Developing Synthetic Psychedelics To Attempt to Fight Mental Illn - Benzinga

The Public Is Being Primed To Feel Groovy About Psychedelic Drugs – CBN News

ANALYSIS

Right now, there is a concerted effort to change the American public's attitude towards psychedelic drugs. Turn on Netflix, Hulu, or other streaming services, and you're likely to find shows and documentaries on the usefulness of drugs like LSD (acid), DMT (spirit molecule), MDMA (ecstasy or mollies), and psilocybin (magic mushrooms). These shows are the first public signs that we are being primed to accept the recreational and "prescription" use of psychedelics to solve both our mental and spiritual ills.

Since the Nixon years, the U.S. Drug Enforcement Administration has marked psychedelics as schedule 1 substances because they lack clinical value, can be addictive, and hold the potential for long-term physiological and psychological damage, including schizophrenia-type symptoms.Given this classification, how does one change public opinion about a class of drugs associated with images tucked firmly in the American consciousness of spun-out flower children whirling around the grass at Woodstock or loitering aimlessly on the streets of Haight-Ashbury?

According to Edward Bernays, the father of public relations and nephew to Sigmund Freud, in order to "manipulate the public to think a certain way, it needs to be taught how to ask for what it (the manipulator) wants." Robert Worchester, a political analyst, described public opinion by making a distinction between attitudes, opinions, and values. He noted that a person's values are the most impervious to change; however, through continued exposure, thought, and discussion, these too can be shaped.

When it comes to influencing our view about psychedelics, what could possibly compete with the images of dancing hippies? What about a growing body of scientific literature that claims the use of these drugs can help resistant anxiety, posttraumatic stress, depression, alcohol, and tobacco abuse?For the past 30 years, research studies involving psychedelics were not backed by public fundsuntil recently. Studies have been popping up in clinicaltrials.gov. There have even been several reports, with small sample sizes, touted as "success stories" for reducing mental health symptoms by microdosing these drugs.

Mental health is certainly a concern for Americans. This week, a Gallup poll found that Americans rated their mental health at an all-time low, with only 34 percent giving themselves an excellent score. Aside from this poll, we know that our society is facing significant mental health challenges, with nearly 20 percent of the population suffering from anxiety disorders and suicide ranked as one of the top 10 causes of death in the United States.

The media is not the only group riding high on our mental health problems. Groups like Mind-Medicine, a pharmaceutical start-up, are seeking FDA (national) approval for psychedelics, under the expectation that the drugs will provide an alternative treatment to the aforementioned mental health conditions. Veterans and first responders have already been enlisted in these studies.

The co-founder of Mind Medicine stated their goal is to "get the average person to realize that these are not evil drugsthey can be used as medicines and be successful at treating unmet medical needs."

Aside from the attempt to lend credibility to these drugs through science, there has already been a push to legalize psilocybin (magic mushrooms). Some states and cities have already moved to legalize these substances for recreational use. These places include Denver, Colorado; Oakland and Santa Cruz, California; Ann Arbor and Washtenaw County, Michigan; Somerville, Cambridge, and Northampton, Massachusetts; Washington, D.C.; and Oregon. Seattle is the largest city to decriminalize all psychedelic plants and fungi for religious, spiritual, healing, or personal growth practices.

California is currently proposing its own measures to legalize psilocybin mushrooms, truffles, sclerotia, and mycelium. Iowa is following suit, but with an additional bill that would reclassify psilocybin, ibogaine, and MDMA for medicinal purposes.

The real goal here is to nationalize the use of these drugs, which have the potential to significantly alter our society and offer bad treatment for those suffering from trauma, anxiety, and depression. The strategy we are seeing to promote psychedelics has been taken right out of the playbook of Big Marijuana. Rather than fight the arduous battle of changing the schedule 1 designation at the federal level, there's a major push to make these drugs respectable. Research studies and popular media will continue to promote medical benefits associated with these drugs, but the endgame is for psychedelics to be legalized at every local and state level for recreational use.

Fighting major pharmaceutical and research industries may seem like an uphill battle. However, there are important steps that we can take to slow this fast-moving train:

Dr. Jennifer Bauwens serves as Director of the Center for Family Studies at Family Research Council. In her role, she researches and advocates for policies that will best serve the health and well-being of families and communities.

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The Public Is Being Primed To Feel Groovy About Psychedelic Drugs - CBN News

Thats an Old Story – The Cut

Mind. Body. Control. Uncover the dark truth inPower Trip, a new investigative series with original reporting fromNew YorkMagazine.

Photo-Illustration: by The Cut; Photos: Provided

In the second episode ofCover Story, Lily Kay Ross recounts her trip to the Ecuadoran Amazon to the podcasts host, iO Tillett Wright. Relating the multiple instances of rape and sexual abuse she experienced at the hands of an ayahuasca shaman and the aftermath when she decided to come forward, Ross portrays a community unwilling to support her or confront its own systemic issues.

Ross: People didnt say, This is your fault. They said things like You manifested this experience so that you could grow as a person. What if he did what he did to heal you?

Not until someone reached out asking for information about the very abuse Ross had experienced did she realize she could find help outside the system that had silenced her. That someone was Dave Nickles, a moderator and editor who runs psychedelic-harm-reduction and education projects. Together, they began to investigate larger issues within the community alongside other testimonies like Rosss. Nickles helped Ross realize that her story was part of a much bigger one one dealing not only with sexual abuse but with power and manipulation in the psychedelic community. Together, they are ready to share what they uncovered.

Mind. Body. Control. Uncover the dark truth inPower Trip, a new investigative series with original reporting fromNew YorkMagazine.

To hear more about Rosss harrowing experience in the Amazon, listen and follow on Apple Podcasts, or wherever you listen, and find the full transcript below.

Just a quick note: This series deals with sexual assault, so please keep that in mind when you decide when and where to read or listen.

iO Tillett Wright: Lily, I know you left the psychedelic world, and I would love for you to talk about the moment where it went from being something safe and something growthful and beautiful to something treacherous and bad.

Lily Kay Ross: Oh boy. That shit was dark theres so much. [Laughs.] The turning point was actually when I had been deeply hurt, and the response I got was if I told the story of what had happened to me, if I kept beating this drum, that I was going to single-handedly destroy the psychedelic renaissance.

Wright: On the off chance that youve never heard of Burning Man, picture 50,000 people in thongs and goggles and furry leg warmers on Technicolor Mad Max bicycles, dancing and tripping in the middle of the Nevada desert. All vehicles there have to be approved by the DMV, the Department of Mutant Vehicles. I am not kidding. Hundred-foot sculptures of sharks and fantasy creatures roll through a temporary city erected and deconstructed every year in celebration of radical self-expression. Naturally, its been a magnet for psychonauts of all kinds and a beacon of outsider culture. But just over a decade ago, tech people started flocking. They were interested in mind optimization, starting to microdose. They wanted shamans to come to their mansions to guide private journeys. That was all part of how the modern psychedelic renaissance started. And Lily was there for it. Literally. In 2008, she was at Burning Man. And slightly annoyed by this one tech guy.

Ross: And this creepy guy was hitting on me.

Wright: Shes there attending some lectures on cool, new psychedelic research.

Ross: One of the things he was puffing himself up about was like he was a wealthy guy, and, you know, funding, psychedelic research, and whatever. Oh, there are these researchers, and theyre trying to do blah blah blah.

Wright: At this point in her life, shes already into critiques of money and power and authority. Shes thinking about how that stuff plays out in the psychedelic world all these white people appropriating Indigenous cultures, questions about who profits. By 2011, thats a lot of what shes studying at Harvard.

Ross: I nerded out, hard-core, on postcolonial theory.

Wright: Thats when she hears about a project in the Ecuadoran Amazon that piques her interest. An Indigenous community wants audio equipment to tell their own stories.

Ross: Which I thought was cool. Even though it was tangential to the guide work and the things I felt called to and pulled to, it was something I was very passionate about and interested in.

Wright: In 2012, she got a grant to go for the summer. Shes going to be working with a local guy who is leading the project there.

Ross: The man who was hosting me was also an ayahuasca shaman, which I didnt know until a few days before I was going down there.

Wright: Should we go to the Amazon?

Ross: Yeah, I guess so. So I got on the plane, it was like six in the morning, and then got into Ecuador late that night. Then I woke up in the morning, and I took a taxi across town to a bus depot. The taxi ride was like an hour. The bus was like eight. And we went out of the Andes and down the mountain into the Amazon.

Wright: This is when Lily first saw the guy she was there to work with, someone were going to call T. She describes him as wearing black jeans and a button-down shirt, a rainbow-beaded headband, and a giant anaconda-skin necklace. He takes her on another two-hour bus ride, they walk across a bridge, and then ride another bus up a mountain.

Ross: And then finally, T kind of indicates to the bus driver who stops and lets us off. Theres no bus stop and theres no city and theres no anything. I dont know if youve gotten this impression yet, but it was remote. We were out there.

Wright: Theres one last car ride, the only taxi around.

Ross: Hes agreed to take us out to the village. And we get out of this car and there I am with T in the dark, and the taxi drives off. Then we had to walk about a mile.

Wright: Its literally four structures in the jungle.

Ross: I was tired. I was thirsty. I was hungry. I was a bit relieved that I didnt have to travel anymore.

Wright: First, T sits her down and talks to her about the village how their whole way of life is under threat and that her role is to document it. Then he takes Lily to a hut with nothing but a little bed and a pallet for her stuff, and she finally gets to sleep. Two days later, she finds T doing a kind of cleansing plant bath on some of the men in the community. Its a ceremonial thing, and he wants to do one on her.

Ross: It was like, Well, this is a thing he does with people. I went into the hut, and I went to my bed. And I was wearing my undergarments, as he had said, and he came in and he had some kind of very aromatic liquid that hed put onto these branches, like leaves. So he covers me head to foot in this stuff and then he says, Just wait here and put your clothes back on. And Ill be back in 30 minutes to come to talk to you.

And then everything just became very, very weird. It felt like my eyes were drying and my mouth was drying and the walls were doing this pulse-y, wavy thing. And I was alone, so I got up and I walked to the door and I was having a really hard time standing up. He saw me standing in the door, and he rushed right over to me, and he kind of took me by the arm and led me back to the bed and kind of had me lie down.

Then he started on this whole thing where he was telling me about our relationship and how this was all meant to be and that uh, that were in love? That was a thing that he declared at that time. And that this was all the will of God. I dont even believe in God, what the fuck is going on?

I couldnt move. I was physically incapable of moving my body, and I had no concept of what was happening. He was sitting behind me and had wrapped his arm around my neck, and he was humping me, he was trying to kiss me, he was I was totally frozen. It took me about ten minutes, from my sense of time, to collect myself and to turn away from him, which I finally did. And then he kind of got up and laughed and got into his bed and went to sleep.

And there was silence. Then there were words, which is not how I usually talk to myself. And the words said, You have to run, you have to get out. Youre being brainwashed. And I heard those words, and I honestly felt paralyzed. I was not the same person after that.

Oh, this is hard. It was like he had commandeered my will. I would have done anything that he told me to do.

Wright: For the next few days, Lily felt like she was in a fog, not in control of her own thoughts. And totally attached to T.

Ross: I was utterly dependent on him, terrified to be away from him, terrified to be near him as well. Bewitched?

Wright: Lily was there 26 days, and T raped her six times, though it took her months to call it that. She told me he kept repeating that their love was the will of the god, the spirits, and his ancestors. That they were in danger, but if she stayed near him, he would keep her safe. He also started giving her ayahuasca.

At some point, an American family came to visit. They were taking their kids on a South American tour, and a local suggested they go off-road and visit an authentic village with a real-life shaman. The mom in the family, her name is Ainlay Dixon. Ainlay and Lily got friendly right away.

Ainlay Dixon: After a while, I realized that she was really out of it. She was really stilted and kind of stoned but in a kind of zombielike way.

Ross: I was a shell by that point. It felt like somebody else had taken over my brain.

Dixon: We had our conversation, and thats when I realized something was really wrong.

Ross: I had pulled aside the mom at one point.

Dixon: We went up to a kind of crawl space at the top of the hut where no one could find us.

And she told me

Ross: So I have this sexual relationship with this guy.

Dixon: And that the shaman had told her that he had four wives and that he was going to leave them all and marry her, and that

Ross: It was like I was watching somebody else talk through my mouth.

Dixon: She explained that this is a person with whom she has a professional relationship but then has come into her bedroom at night. And this is what happened. And dah, dah, dah, dah, dah. I was very taken aback, not by what she was saying but the way she was speaking.

Ross: I was trying to get somebody to help me, but I wasnt in a place where I could articulate I think I need help.

Dixon: I mean, this is the ultimate isolation. She saw nobody. She only saw the three or four people who were in this little compound.

Ross: Meanwhile, he was telling me overtly, Im going to get you pregnant, and were going to have all these children and youre going to live in the Amazon.

Dixon: And I was like, You know, honey, I think you might not trust everything hes telling you.

Ross: She seemed a bit like, Oh yeah, I mean, hes handsome. I could see it, just be careful and dont get too caught up.

Wright: So Ainlay and her family leave, and Lilys still in the village. A couple of days later, T takes Lily to his wifes house in a city about an hour away. She borrows his computer to check her email and sees that she has a message.

Ross: I got this email from Ainlay Dixon, and it says, Hey, Lily, Ive been wondering about sending this email for a while and finally decided to do it.

Dixon: We met some people, and they seemed to have a very different impression of T and not a good one.

Wright: Ainlay lays out that once she left the village, she couldnt get Lily out of her mind. Shed started poking around, asking questions about T. And what the locals told her was really dark.

Dixon: [Reading the email.] The Indigenous group he is part of, themselves find him to be a disgraceful charlatan wearing a jaguar skin, exaggerated feather headdress, exaggerated face paint, and playing supposed native music with non-native guitars and charangos.

Ross: Some of what they said was too fantastical to believe, such as being mixed up in trading shrunken heads and a local leader being killed when he tried to investigate.

Wright: T was investigated in connection to that killing, but he was never charged. Some Ecuadoran papers had covered it.

Ross: As I was finally getting to the point of going, Holy shit, like, I think this guy is a murderer,I started to hear his footsteps walking up the footpath.

Wright: This is where this becomes like an escape scene in a movie. In a split second, Lily comes up with a story about her dad being sick.

Ross: Ive just heard from the doctors, and my dads in the hospital and theres something wrong with his prostate and Im scared and they dont know whats wrong.

Wright: She tells T that she needs to stay in the city for the night to sort out the details. She convinces him. She frantically makes a call and gets American Airlines to waive the change fee and put her on the next flight she can catch. And in the morning, she makes a break for it.

Ross: I was looking over my shoulder every step of the way, thinking, Is somebody following me?

Wright: With nothing more than her purse which, at the last minute, shed thrown her passport into Lily hops on a bus, gets herself to the airport, on a plane, and to her family in L.A.

Ross: The further I got away from him and the village, the more that I felt that, This is real. And some really bad stuff has just happened.

Wright: That whole escape saga was all very dramatic. But its what happened next that changed the course of Lilys life.

Dave Nickles presenting at the 2012 Psychedemia conference, where he met Lily Kay Ross. Photo: Provided

Ross: My dad picked me up from the airport, and I remember how warm his hug was. I got home, took a shower, and did everything I could to just feel normal. I put on my favorite clothes and my favorite earrings and tried to do what I could to have a sense of my identity and feel like myself again.

Wright: For a while, Lily was just trying to make sense of what happened to her.

Ross: Like, Was this a consensual relationship? There were periods where I did resist it. I was really clear, like, This is not what I want. When I went to the crisis center for my intake, I was sort of like, Are they even going to take me? Because I dont know if what I went through counts.

Wright: It took Lily months and months before she even talked to her dad about what happened.

Ross: I remember what I said to him. I said, During my time in the Amazon, T was raping me. And my dad was there for me. He said, You know, Lily, Ive tried to say this before, but I think he drugged you. At first, I was very resistant. I was like, Well, I took ayahuasca, but that was after. And it was this whole other thing, and he kept pressing the issue. That was when something started to dawn on me: Well, there was that one night where I was paralyzed, and everything was going all wompy and wonky and weird. Then I remembered that he had covered my body with this liquid thing.

I had this conversation with Dad, realized I had been drugged, and did some research. I went, Holy fucking God, this is so much worse than I thought it was. This makes so much more sense. This asshole drugged me and brainwashed me.

Wright: Lily came to believe that the plant bath contained this drug called scopolamine, which, after our interview, I had to look up. I highly recommend you give it a Google yourself because this drug is batshit. They call it the zombie drug because high doses can put you in a state where its hard to assert your free will. Gangsters love it because people will just hand over their bank cards or car keys when they demand them.

By the way, New York Magazine called T, and he denied drugging or raping Lily. He basically said in his culture it was natural to have sex with lots of women but said it was never by force.

But after that conversation with her dad and her research, Lily was clear: This man had used his authority as a shaman, in combination with drugs, to control and rape her. The idea of someone, anywhere, of any culture, using these drugs to control another person makes me think of something Dr. Grob said. Remember that UCLA researcher who took us to Mr. Rogerss Psychedelic Neighborhood? He was telling me about some research he did in 93, observing how ayahuasca was used in religious ceremonies in the Amazon, and he noticed this particular way this minister would use the drug. Once his congregants were in a suggestible state of mind from the ayahuasca, he would give them life tips.

Charles Grob: To be responsible to their spouses, their parents, their children, their employers, across the board. I remember one night, I was at a ceremony and my translator had kind of snoozed off, so I gave her a nudge and asked what they were talking about. Oh, she said, theyre talking about how important it is that if you say youre going to be somewhere, you are there. And I thought, This explains a lot. Individuals who had started at the bottom rung of the socioeconomic ladder had risen to be successful in their jobs, in their family lives. I thought, Wow, so much has seemed to do with this heightened receptivity they must have had.

Wright: These drugs can give a person so much power to influence others. So the thing to look at is how do they use that power, and what are they influencing others to do? In the next breath, Dr. Grob was reminding me of a story I already know, that you probably know too, about a famous group of Californians in the 1960s.

Grob: You have an old example of the Manson Family. He would dole out LSD to his followers and then he would launch into these bizarre fantasy-ridden speeches that eventually led to their following his instructions to go commit murder and mayhem. It was a horrible situation, but I think probably a telling example of what could happen when these compounds are employed by an unscrupulous, unethical, immoral cult leader.

Wright: Basically, Dr. Grob was warning me that these drugs can be tools to manipulate people, whether among all the different groups in the Amazon or in the overwhelmingly white underground world of psychedelics that Lily was part of. And that was the worry that started to bubble up for Lily after she came out of the very dark hole she was stuck in.

Ross: I was quite fixated on what had happened. I was not sleeping at night and sleeping during the day. I am in a lot of pain and I am drinking too much whiskey and it was just all pain all the time.

Wright: Eventually Lily started talking to her circle of friends a little about it, and it went fine. They were sympathetic and horrified. But then she started to go and tell people in the psychedelic community.

Ross: At that point, I considered psychedelics part of what was helping me heal. So it seemed to me like a way to be nuanced and be like, Look, theres this potential and then theres this other, darker potential. Lets consider that. But it was the people that I knew through psychedelics and psychedelic conferences and the Guild of Guides who were responding in really weird ways.

Wright: The Guild of Guides a.k.a. the Convivium is that underground conference where people who practice psychedelic therapy met to discuss their work. Some of these people were saying things that messed with Lilys mind.

Ross: I was on the phone with somebody I had met at the Guild of Guides. He said something like, You cant call it rape because if you call it that, then youre giving all your power away. If you call it rape, then you make yourself a victim.

Wright: It did not get better from there.

Ross:People didnt say, Well, this is your fault. They said things like You manifested this experience so that you could grow as a person. What if he did what he did to heal you? That reshapes it as a positive thing. Oh, good on you. Arent you such a brave soul? You gave yourself this opportunity for growth and healing.

Wright: And she thought about that. Like, maybe there was some weakness in her that he exploited.

Ross:I wanted to figure out if this was mommy issues? Was this daddy issues? Was this me looking for safety? Was there something about the fact that my mom had died that meant I was seeking something that I thought he could provide?

Wright: Lily went around and around like that for a while. Is it me? Do they suck? Or is it me? And eventually, it was this one particular line she heard from a few people that set something off in Lily.

Ross: It was, Oh yeah, thats an old story. Shamans or people sleeping with their clients or whoever is an old story. Oh, this has been going on since the beginning.

Wright: An old story? Thats been going on from the beginning? Meaning there are rapists in our midst? And everyone knows it? When she put that chain of thoughts together, another part of Lilys brain kicked in. The skeptical, questioning part. The part of her that, throughout all her years in the psychedelic underground, had been a little concerned about certain dynamics between guides and their clients.

Ross: Who are these people that are dispensing these drugs to a roomful of people? What kind of training do they have? Is this wise? Is this safe? Is this a good idea? People would call themselves shamans; is that a thing that one calls themselves? Are these people doing a good job? And who decides? Is there somebody that authorizes this? That says you have the seal of approval that we know youre not a dick and youre competent in this? Where do people go if they get hurt or if somebody does something wrong?

To my mind, these realms are real and good. Intentions are not enough when it comes to claims to shamanic power because power is seductive, and without proper guidance, claiming power is a slippery slope.

Wright: Lily gave this talk a couple of months after she got home from the Amazon. And its weird to listen to now because its from a period when she was still in a daze and hadnt processed anything or even figured out the basics of what happened to her. But in her words, you hear hints of a future Lily the one who is past looking inward, inward, inward.

There are a few reported deaths now from ayahuasca in Peru and Ecuador and increasing reports of sexual transgressions and rape. If we are not willing to address this, what does this say about us as a community who love psychedelic plant medicines and what they have to offer us? If we dont talk about this, if we are silent, are we not then complicit?

Wright: To Lily, these questions felt more important than ever. Because the psychedelic renaissance was becoming an actual thing which meant that more and more vulnerable people might be turning to psychedelic guides. Which meant that what happened to Lily could happen to them. But the guides themselves, some of them seemed focused on a different danger, which became clear to Lily during this one last twisted conversation she had with a woman who was known as a teacher and a scholar. An adviser to a lot of important groups. A well-respected elder. Lily told her she wanted to speak to the press about the danger of abuse.

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Thats an Old Story - The Cut

Looking Into The Florida Bill That Proposes Decriminalization Of Psychedelics (And Every Other Illegal Dr – Benzinga

This article by Emily Jarvie was originally published on Psychedelic Spotlight, and appears here with permission.

A new bill filed in Florida has proposed the decriminalization of psychedelics, along with the rest of currently illegal drugs, and the promotion of rehabilitation instead of criminalization for drug-related offenses.

Democratic RepresentativeDotie JosephfiledHB 725, titled the Collateral Consequences of Convictions and Decriminalization of All Drugs Act, last Tuesday.

The bill proposes that crimes associated with the personal use and possession of controlled substances that do not involve production, distribution, or sales be decriminalized in favor of civil fines or referral for drug rehabilitation.

The Legislature intends the prioritization of rehabilitative health intervention in lieu of criminalization for personal usage of controlled substances, including but not limited to, stimulants, including cocaine, methamphetamine, opioids, heroin, fentanyl, depressants or benzodiazepines, and other addictive controlled substances, the bill states.

It would also compel the Department of Health to conduct a study on more effective methods of addressing drug addiction instead of criminalization. This study shall include but not be limited to supervised drug consumption in facilities, which have been proven to reduce public disorder associated with drugs, and lead to a drop in the behaviors linked to HIV and Hepatitis C transmission; programs that have been successful in Seattle, San Francisco, and Philadelphia; and any other rehabilitative centered solutions, the bill says.

The aim of the legislation is prioritizing treatment and safety in an effort to preserve lives rather than discard them through criminalization and incarceration . . . in the interest of the health and public safety of the residents of Florida, preserving individual freedoms without sacrificing community costs, allowing law enforcement to focus resources on violent and property crimes, generating revenue for education, substance abuse prevention and treatment, freeing public resources to invest in communities and other public purposes rather than continuing to overburden prisons with a population that needs medical attention, seeking corrective equity on the impact of the war on drugs, and identifying real people-centered solutions to various drug crises like the opioid epidemic.

There is evidence that the widespread decriminalization of all drugs can lead to a dramatic drop in drug overdoses, HIV infection, and drug-related crime, as demonstrated by Portugal, whichdecriminalized all drugsin 2001.

Should this legislation go into force, Florida would become the second state in the United States to decriminalize all drugs. This comes after Oregon passedMeasure 110on November 3, 2020, which downgraded the personal non-commercial possession of controlled substances to a Class E violation a maximum fine of $100 whichcan be waivedif a person undergoes a health assessment that leads to addiction counseling.

Abillintroduced in the U.S. Congress in June has also proposed an end to criminal penalties on a federal level for the personal use of illegal substances, including Schedule I and II drugs.

To date, other jurisdictions in the United States have adopted less radical drug decriminalization measures, with cities such asDetroit,Seattle, andWashington, D.C.voting for the decriminalization of psychedelics including fungi and plant-based entheogens.

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Looking Into The Florida Bill That Proposes Decriminalization Of Psychedelics (And Every Other Illegal Dr - Benzinga

When Lincoln Center Comes Down From This Trip, Theyre Going to Feel Weird – Vulture

From Flying Over Sunset, at the Vivian Beaumont. Photo: Joan Marcus

I spent the morning after seeing Flying Over Sunset the same way I assume everyone else did surfing Wikipedia. There was so much history, referenced so sloppily, during James Lapine, Tom Kitt, and Michael Kories ill-conceived musical about psychedelics that I needed a next-day huddle with my computer. Those hours I spent with my laptop were the best ones that the musical brought me. Footnotes! Cross-references! I believe that internet binge gave me the same high the creative team must once have felt the intoxication of learning about real people and diving into the details of their lives.

In interviews, the musicals book-writer and director James Lapine has spoken about finding the inspiration for Flying Over Sunset in a biography of Clare Boothe Luce, the mid-century playwright and politician who became a towering figure of American conservatism. Luce took LSD for psychiatric reasons, and she was linked to the consciousness pioneer Gerald Heard, himself a dear friend of the writer Aldous Huxley. This daisy-chain acquaintanceship interested Lapine. The real Cary Grants own interest in acid then offered him a fourth LSD-curious celeb running around California in the 50s, and as anyone knows, once four celebrities (possibly) meet, youve got to make a show about it. (You do not.)

Our first voyager, Huxley, played by Harry Hadden-Paton, has his initial drug experience in a Rexall Drug. (So far, so true: Huxleys book The Doors of Perception contains the account of this experiment with mescaline.) As his wife (Laura Shoop) and Heard (Robert Sella) try to tug him out of the magazine aisle, Huxley sing-talks about imagining the Biblical Judith as she emerges from a Botticelli painting. Hes tripping hard: The curving white walls of Beowulf Boritts set invert; projected images crawl all over them; a little video fish wriggles inside a spherical lamp. But for all this visual hullabaloo, were not meant to think about Judith beheading Holofernes. The image does not set up a theme or a motif or illuminate some unseen truth. The shows songs lush but dull music by Kitt, lyrics by Korie all show us acid trips, yet the grindingly inert and ineffectual Judith number makes you keen never to share one of these hallucinations again.

Huxleys wife quickly expires slowly tap-dancing chorus members remind you of Deaths steady tread and she haunts him by drifting in and out of his LSD experiences. For the rest of the show, Huxley will have one directive: to dance again with her. Like Huxley, Luce (the dazzling Carmen Cusack) is also in mourning. We see her sad about any number of things: her sexually loose mother, a contentious Senate hearing over her appointment as an ambassador, and her teenage daughters death in a car wreck. As with Huxley, the things that make the historic person fascinating are subsumed by the show into one basic therapy revelation Luces Senate stuff vanishes fast, but we spend a lot of time on the dead daughter, whose absolution she craves. At one point or another, characters will raise their divisions on issues of public morality or war, but theyre hushed by Gerald. No politics! he cries, which effectively cuts off anything that might stimulate conflict or conversation. Just as Huxleys wife dogs his steps, ghosts tailgate Luce. Again Lapine calls upon choreographer Michelle Dorrance to set the vibe. The gloomy dead tap-walk in a gloomy tap-circle. Step drag step drag.

Cary Grant may never have met the other three, but Lapine distorts reality to get him there. Even within the spaced-out logic of the show, its never plausible that the star would meet these other seekers and decide to get high with them on a beach. (Tripping in Malibu is the entirety of the deadly second act.) Certainly Tony Yazbecks Grant seems ill at ease, even apologetic, throughout. Though to be fair, he has the hardest job of the four: Cary Grant is a known quantity even in 2021, so theres the familiar accent and the stiff-spined, gliding grace to try to copy. Yazbeck makes a hash of the voice, and he displays a different, more percussive grace, but at least he has barrels of that: The moments when the show stops to let him tap-dance with a vision of his precociously talented child self (Atticus Ware) are by far its best. Its too bad that baby Cary has to then join the Baggage Parade (step drag step drag), and eventually, in a watery vision, get washed out to sea.

The key post-show discussion question in my small group was How did this get made? The Vivian Beaumont is a big house to sign over to a musical so dramaturgically inept, so lacking in connection, philosophy, or fire. I can understand if at first the Lincoln Center folks were persuaded by the teams collective resum: the performers are strong, Lapine wrote the book for Sunday in the Park With George, and Tom Kitt composed Next to Normal. But there were workshops! There were opportunities to see Yazbeck blush his way through a number in which Grant thinks he is a giant penis blasting off from earth like a spaceship, and to see how bland and puerile such a scene winds up being in execution.

The most you can say for the shows acid-trip stuff is that it sometimes shows a juvenile, snickering humor: After Carys phallic blastoff, we see Clares vision of the afterlife, which looks like a huge ferny mandala, a giant green yonic symbol with her dead mother sitting right at the center. Tee-hee! I can picture someone thinking. Clares slutty mother is in a purgatory that looks like a big vagina! Im not saying this was a wonderful moment: I would need to be extremely high myself to think this was hilarious stuff. But I can at least imagine a version of the show in which it was funny. Thats the thing, really our conscious imagination is more powerful than the subconscious. We learn early in the production that a trip, like a dream, is a private experience, full of the minds rich colors. Make something up, tell a story, you can keep us interested for hours. But other peoples drug experiencesand if you have stoner friends, you will recognize thisdie the moment you narrate them. Dream-colors fade into gray in the spotlight; all the projections in the world can not make them bright again.

Flying Over Sunset is at the Vivian Beaumont Theater through February 6.

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When Lincoln Center Comes Down From This Trip, Theyre Going to Feel Weird - Vulture

"The New Cannabis" the present and future of psilocybin as a medical treatment in Canada – Lexpert

Recent research has shown that psilocybin has the potential to treat a number of mental illnesses. These include suicidality, anxiety disorders, obsessive-compulsive disorder, alcohol dependence, tobacco cessation, and post-traumatic stress disorder, among others. Studies have also found that psilocybin can allow patients, with the help of trained therapists, to confront fears and feelings that are otherwise too traumatic. This ongoing research aims to assess the immediate and long-term psychological effects of psilocybin use.

One area of particularly strong focus in Canada has been on the potential use of psilocybin for relieving end-of-life distress for palliative patients. Proponents view psilocybin as providing relief from mental distress when traditional treatment options fail for terminally ill patients as is often the case. This interest in psilocybin as a treatment also extends into the potential for treatment of the bereaved.

Given its potential benefits, why is the use of psilocybin illegal in most cases today?

As mental health awareness grows, psilocybin has become the focus of increased attention by Canadian health authorities and researchers as a possible treatment for a variety of mental illnesses. However, this has not always been the case.

Psilocybin is a psychedelic. Psychedelics, also known as hallucinogens, are psychoactive substances that produce changes in perception, mood, and cognitive processes. While most people consider psychedelics to be a recreational drug and often associate them with the counterculture of the 1960s, psychedelics have a long history of medicinal use. Unfortunately, due to negative public and political perceptions, little research occurred in this area for decades.

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"The New Cannabis" the present and future of psilocybin as a medical treatment in Canada - Lexpert

PharmaDrug Announces Addition of Dr. Cindy Hutnik, President of the Canadian Glaucoma Society to Their Scientific Advisory Board to Enhance Ongoing…

Toronto, Ontario--(Newsfile Corp. - December 13, 2021) - PharmaDrug Inc. (CSE: PHRX) (OTCQB: LMLLF) ("PharmaDrug" or the "Company"), a specialty pharmaceutical company focused on the development and commercialization of controlled-substances and natural medicines such as psychedelics, cannabis and naturally-derived approved drugs, pleased to announce the addition of Dr. Cindy Hutnik to its scientific and clinical advisory board. Dr. Hutnik will assist the Company in its ongoing efforts to develop N,N-dimethyltryptamine ("DMT") and other related tryptamine analogues as a potential treatment for glaucoma.

Dr. Hutnik, a full professor in the Departments of Ophthalmology and Pathology at the Schulich School of Medicine and Dentistry, is internationally recognized for the significant contributions she has made in understanding the basic pathophysiology of glaucoma, as well as the practical application of this knowledge in her clinical practice. Dr. Hutnik is the current President of the Canadian Glaucoma Society and is a Board member of the Glaucoma Research Society of Canada. Previously, she served as Medical Director of the Ophthalmology Basic Science Laboratory at the Lawson Health Research Institute in the Center for Clinical Investigation and Therapeutics for 18 years, and Chair of Research in the Department of Ophthalmology for 15 years. Her major research interest is focused on the pathophysiology and management of glaucoma with a sub-interest in ocular surface and macular disease. She has supervised and mentored in focused research activities more than 175 students at all levels of training ranging from high school to graduate science and medicine. Her work has been presented and published both nationally and internationally and has been recognized with over 90 awards. With deep industry connections, Dr. Hutnik continues to have keen interest in translating novel discoveries into innovative treatments for patients with glaucoma.

Dr. Hutnik, commented, "I am very excited to work with PharmaDrug in supporting their research and development initiatives in discovering novel uses and formulations of 5-HT receptor agonists, as a potential treatment of glaucoma and other underserved ophthalmology indications. PharmaDrug's candidate molecule studies, currently being conducted at the renowned Terasaki Institute, represent an exciting, paradigm shifting approach to improving outcomes for patients suffering from glaucoma."

PharmaDrug's Candidate DMT-Analogue Molecules Display Low Cytotoxicity

Under an ongoing sponsored research agreement with Terasaki Institute of Biomedical Innovation, the Company has initiated in vitro studies to assess the impact (cytotoxicity, potency and duration of activity) of its two candidate molecules on specific cell types known to regulate pressure disequilibrium in the eyes of patients suffering from glaucoma. Initial in vitro cytotoxicity studies on the Company's two candidate tryptamine molecules have now been completed and the data shows exceedingly low/absent impact on cellular viability across a concentration range that exceeds what is expected to be used clinically. Further functional data from the ongoing 2-dimensional cell culture studies is expected in January. Those data will be extended by investigating the impact of the lead candidate molecule in 3-dimensional microtissue studies aimed at specifically assessing smooth muscle contractility; a response understood to be critical in maintenance of healthy eye function.

The company believes with the engagement of Dr. Hutnik, its access to world class basic science and clinical expertise in ophthalmology has been significantly enhanced. Following the completion of in vitro studies, the company will proceed to IND-enabling efficacy studies using a well accepted animal model of glaucoma. The in vivo studies are expected to begin in the second quarter with a focus on evaluating tolerability and efficacy (ability to lower intraocular pressure "IOP") when applied as a topical eyedrop in animal models of glaucoma. These studies will then be followed by development and testing of a purpose-built medical device capable of delivering sustained, local, sub-psychotropic levels of the development candidate to patients afflicted with glaucoma.

"We are very pleased to have Dr. Hutnik join us as a scientific and clinical advisor for our ophthalmology program, and we look forward to her contributions as we advance the research and development of our novel formulation in the treatment of glaucoma," said Daniel Cohen, Chairman and CEO of PharmaDrug. "Dr. Hutnik is a highly regarded, leader in the field of glaucoma, and she brings invaluable guidance and clinical trial experience having served as Principal Investigator on various clinical trials in the glaucoma space."

Unmet Medical Need For Glaucoma

Glaucoma is the second most common cause of blindness around the world. The global prevalence of glaucoma in people aged 40-80 years is estimated to be 3.5%1. Currently there are over 3 million people living with glaucoma in the US. In addition to the significant personal toll glaucoma takes on sufferers, the related costs and productivity losses now approach $3 billion in the US annually2. Increased IOP is a common feature noted in multiple types of glaucoma, that when left untreated, results in progressive and irreversible vision loss as a result of damage to the optic nerve.

Current treatments for glaucoma consist of surgery and/or topically administered eye drops that are aimed at lowering IOP. Despite widespread use of topical agents, protection from the cumulative harm of elevated IOP remains significant. As such, opportunities related to improved patient care and outcomes are sorely needed. Development of novel IOP lowering agents formulated using approaches that reduce common side effects and improve patient compliance continue to represent the cornerstone of novel treatments.

The Potential For DMT In Ophthalmology

Serotonin receptor 2a (aka 5-HT2a) is prominently displayed in areas of the eye that are known to be vital in the control of IOP. Basic research has shown that topical application of 5-HT2A agonists, including several analogues of DMT, potently reduce IOP in animal models of glaucoma3. DMT belongs to a class of compounds collectively referred to as tryptamines. Multiple different tryptamine family members have previously been shown to improve experimental models of glaucoma, however poor metabolic stability and solubility made them poor development candidates3. Leveraging existing knowhow in the DMT space, PharmaDrug intends to develop a metabolically stable, controlled release analogue of DMT for lowering elevated IOP. Our formulation will reduce the need for frequent re-application and in so doing, improve patient convenience and compliance.

A half century ago, with the passing of the Controlled Substances Act, almost all research directed at harnessing the promising therapeutic potential of psychedelics to treat serious, unmet medical needs all but ceased. The recent resurgence of research in psychedelics is just now beginning to take shape. We believe that our ongoing investment in high quality, foundational academic research combined with our translational activities focused outside of the neuropsychiatric space has strong strategic merit and is backed by sound mechanistic understanding.

About PharmaDrug Inc.

PharmaDrug is a specialty pharmaceutical company focused on the research, development and commercialization of controlled-substances and natural medicines such as psychedelics, cannabis and naturally-derived approved drugs. PharmaDrug owns 100% of Pharmadrug Production GmbH ("Pharmadrug Production"), a German medical cannabis distributor, with a Schedule I European Union narcotics license and German EuGMP certification allowing for the importation and distribution of medical cannabis to pharmacies in Germany and throughout the European Union. PharmaDrug recently acquired Sairiyo Therapeutics ("Sairiyo"), a biotech company that specializes in researching and reformulating established natural medicines with a goal of bringing them through clinical trials and the associated regulatory approval process in the US and Europe. Sairiyo is currently developing its patented reformulation of cepharanthine, a drug that has shown substantial third party validated potential for the treatment of COVID-19 and rare cancers. Sairiyo is also conducting R&D in the psychedelics space for the treatment of non-neuropsychiatric conditions. The Company also owns 100% of Super Smart, a company building a vertically integrated retail business with the goal to elevate the use of functional mushrooms, and psilocybin mushrooms where federally legal, as natural based medicines.

For further information, please contact:

Daniel Cohen, Chairman and CEO dcohen@pharmadrug.co (647) 202-1824

Caution Regarding Forward-Looking Information:

THE CANADIAN SECURITIES EXCHANGE HAS NOT REVIEWED NOR DOES IT ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.

This press release contains "forward-looking information" within the meaning of applicable securities legislation. All statements, other than statements of historical fact, included herein are forward-looking information. Generally, forward-looking information may be identified by the use of forward-looking terminology such as "plans", "expects" or "does not expect", "proposed", "is expected", "budgets", "scheduled", "estimates", "forecasts", "intends", "anticipates" or "does not anticipate", or "believes", or variations of such words and phrases, or by the use of words or phrases which state that certain actions, events or results may, could, would, or might occur or be achieved. In particular, this press release contains forward-looking information in relation to: the development and commercialization of cepharanthine, the results of the Company's research and development in the psychedelics space and the development of the Supersmart business . This forward-looking information reflects the Company's current beliefs and is based on information currently available to the Company and on assumptions the Company believes are reasonable. These assumptions include, but are not limited to the ability of the Company to successfully execute on its plans for the Company and its affiliated entities; the ability to obtain required regulatory approvals and the Company's continued response and ability to navigate the COVID-19 pandemic being consistent with, or better than, its ability and response to date.

Forward-looking information is subject to known and unknown risks, uncertainties and other factors that may cause the actual results, level of activity, performance or achievements of the Company to be materially different from those expressed or implied by such forward-looking information. Such risks and other factors may include, but are not limited to: general business, economic, competitive, political and social uncertainties; general capital market conditions and market prices for securities; the actual results of the Company's future operations; competition; changes in legislation affecting the Company; the ability to obtain and maintain required permits and approvals, the timing and availability of external financing on acceptable terms; lack of qualified, skilled labour or loss of key individuals; risks related to the COVID-19 pandemic including various recommendations, orders and measures of governmental authorities to try to limit the pandemic, including travel restrictions, border closures, non-essential business closures, service disruptions, quarantines, self-isolations, shelters-in-place and social distancing, disruptions to markets, economic activity, financing, supply chains and sales channels, and a deterioration of general economic conditions; and a deterioration of financial markets that could limit the Company's ability to obtain external financing.

A description of additional risk factors that may cause actual results to differ materially from forward-looking information can be found in the Company's disclosure documents on the SEDAR website at http://www.sedar.com. Although the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. Accordingly, readers should not place undue reliance on forward-looking information. Readers are cautioned that the foregoing list of factors is not exhaustive. Readers are further cautioned not to place undue reliance on forward-looking information as there can be no assurance that the plans, intentions or expectations upon which they are placed will occur. Such information, although considered reasonable by management at the time of preparation, may prove to be incorrect and actual results may differ materially from those anticipated.

The Company's securities have not been registered under the U.S. Securities Act of 1933, as amended (the "U.S. Securities Act"), or applicable state securities laws, and may not be offered or sold to, or for the account or benefit of, persons in the United States or "U.S. Persons", as such term is defined in Regulations under the U.S. Securities Act, absent registration or an applicable exemption from such registration requirements. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the securities in the United States or any jurisdiction in which such offer, solicitation or sale would be unlawful.

Forward-looking information contained in this press release is expressly qualified by this cautionary statement. The forward-looking information contained in this press release represents the expectations of the Company as of the date of this press release and, accordingly, are subject to change after such date. However, the Company expressly disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, except as expressly required by applicable securities law.

References:

1) Kang JM, Tanna AP. Glaucoma. Med Clin North Am. 2021 May;105(3):493-510. doi: 10.1016/j.mcna.2021.01.004. Epub 2021 Apr 2. PMID: 33926643.

2) https://www.brightfocus.org/glaucoma/article/glaucoma-facts-figures

3) May JA, McLaughlin MA, Sharif NA, Hellberg MR, Dean TR. Evaluation of the ocular hypotensive response of serotonin 5-HT1A and 5-HT2 receptor ligands in conscious ocular hypertensive cynomolgus monkeys. J Pharmacol Exp Ther. 2003 Jul;306(1):301-9. doi: 10.1124/jpet.103.049528. Epub 2003 Apr 3. PMID: 12676887.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/107336

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PharmaDrug Announces Addition of Dr. Cindy Hutnik, President of the Canadian Glaucoma Society to Their Scientific Advisory Board to Enhance Ongoing...

Will this music alter your mind? The most terrifying thing can do that – Sydney Morning Herald

His collaborator Kaelen also runs a company called Waveform, which makes AI-generated soundtracks for use in psychedelic therapy. Hopkins is a Waveform investor. Brian Eno is a mentor of sorts to Hopkins, has collaborated with him many times and is also involved. Kaelen took a high quality Fostex field recorder. Hopkins had with him a Bose portable speaker. He put the Bose at one end of the underground cathedral with Kaelen at the other, and he played pieces of music and sound through the speaker for him to record, 50 metres away. One of them was a drone from a crystal bowl, previously recorded by Hopkins; it became the opening soundscape of Music for Psychedelic Therapy.

If someone is going to invite me to do something that I would never do, in an extraordinary place, then ... it seems you have to go for it.

It was very important to me to use the cave as a way of processing the sound. Like a reverb. That had to be the starting point so that it really felt like the music began with the cave and grew out of it, Hopkins explains.

He had already made music for legitimate psychedelic therapy, for Waveform, for use as an adjunct in clinical settings in university research trials. This album is like a commercially available version of those. It includes, at the end, excerpts of a lost talk by the late spiritual teacher Ram Dass.

Like the sharing circle at the end of the session, says Hopkins. His track [Sit Around The Fire, featuring Das and musician East Forest] is very grounded, so its only piano and voice and fire, and a few little bits of processing, but not very much. Whereas everything else on the record is far more difficult to describe in terms of, well, what instrument is that?

In the spirit of Dass, Hopkins wanted to remove himself from the musics imprint and try for the ultimate musical and psychological goal of absolute purity.

Deep in the woods of Devon, in the far south of England, Hopkins collaborated with musician 7Rays. His name is Dan, he says, we have been friends for a very long time. Hes very literally bought that woodland energy into the work. The pair hung speakers from trees to play sounds through them to be recorded and processed.

To me those pieces sound very, very like the experiences Ive had in the DMT realm, says Hopkins. Thats something that weve shared, so theyre almost like downloads from that space, and very, very in tune with the woods.

Hopkins was a late-bloomer with psychedelics. He only put them (and ketamine) into the mix when he reached 35, about seven years ago, shifting his music production in the process increasingly towards stillness.

Ive always had spiritual experiences dating back to teenage years, but I didnt really understand them particularly well until I meditated for a certain amount of time myself and read a certain amount about what might be going on behind that, he says.

The era that were in has become increasingly fraught and unpredictable. I felt like I had no choice but to make something that was so direct. Purity is certainly what I hope people feel from it. I tried to get myself out of the way and let myself be the vessel.

Jon Hopkins performing in Denmark in 2019. He says he will make dance music again, but his latest work conjures stillness.Credit:Getty Images

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He wanted to eliminate the ego by eliminating the dance beats, the kickdrums. I dont denigrate what Ive done before, and I will definitely want to make dance music again. But to get that out of the way left all this space for really exploring the sonics and the melody and what we can do with illusions and dimensions.

Hopkins involvement in psychedelic-assisted therapy for mental illnesses, such as depression and post-traumatic stress disorder, comes as the field begins to boom worldwide, including in Australia, backed by investors, governments, and institutions including universities. It is only now beginning to be freed from the shackles of Richard Nixons War On Drugs, which created difficulties for clinical researchers testing substances such as MDMA and psilocybin. Research over the past five years has shown them both to be effective in treating depression and PTSD, alongside therapy.

Hopkins calls the substances medicines. The medicines themselves have quite a loud voice in this music. Definitely louder than my own. Theres no actual separation for me between the natural world and those medicines, because they are things that grow in the ground, psilocybin and DMT especially.

I love the poetic idea that this is music that comes from the earth.

Music for Psychedelic Therapy is out now.

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Will this music alter your mind? The most terrifying thing can do that - Sydney Morning Herald

Psychedelics can change humanity for the better. Its time to unlock their power – The Guardian

I study psychedelics. The organization I work for the Multidisciplinary Association for Psychedelic Studies (MAPS) has been researching MDMA since 1992, seven years after the substance was prohibited. Our organization was founded in 1985.

One of a few treatments designated a breakthrough therapy by the FDA, MDMA-assisted therapy for post-traumatic stress disorder is an incredibly promising treatment for this devastating mental injury. Survivors of PTSD may struggle to stay connected in their work, families, and communities. They often live with symptoms like insomnia, hyper-vigilance and isolation; these commonly lead to substance use disorder, depression, chronic pain or heart problems. Yet most of the available treatments provide symptom relief for only about half of the people with the diagnosis, with even fewer people experiencing remission.

In May 2021, Nature Medicine published the results of the most advanced trial of psychedelic therapy to date. In our Phase 3 trial of MDMA-assisted therapy for PTSD, 88% of participants who received MDMA in conjunction with trauma-focused therapy experienced a clinically significant reduction in symptoms; 67% of participants no longer met criteria for a PTSD diagnosis. Many participants reported MDMA-assisted therapy helped them address the root cause of their trauma for the first time.

An exploratory study suggests a role for MDMA in couples therapy. MAPS has combined its MDMA-assisted therapy protocol with Cognitive Behavioral Conjoint Therapy (CBCT) for PTSD, in which both the person with PTSD and their partner are administered MDMA. Results demonstrated dramatic reductions in PTSD symptoms and partner accommodation, improving the quality of relationships for six couples.

Ketamine studies have shown promise for chronic suicidal tendencies, PTSD symptoms and depression. Legal ketamine clinics which pair therapy with the drug can play a key role in maximizing the benefits and reducing the risks of the psychedelic experience. Psilocybin-assisted therapy is a breakthrough therapy for depression. Ibogaine may be an effective treatment for opioid use disorder.

In fact, four separate systematic reviews have been published this year highlighting the potential of psychedelic-assisted therapies for those conditions and more: end of life care, brain injury, neurodegenerative disorders, mood disorders, smoking cessation and addiction or dependence. Dozens of studies make a compelling case for rapid expansion of research into psychedelic-assisted therapies for serious mental health conditions.

Evidence indicates that psychedelic use is associated with pro-social, personal growth benefits including increased nature relatedness, potentiating conflict resolution and sustaining compassion among first responders. Indigenous communities around the globe have used psychedelics in spiritual ceremony and healing for millennia.

Conversely, the well-documented devastation of the war on drugs has been responsible for untold trauma. But is the legalization and regulation of all substances reversing the course on the war on drugs too dangerous? Simply: No. Its more dangerous not to.

Decades of research and far more extensive use outside clinical settings demonstrate that the risks of drugs, for most people, are generally short-term and manageable through compassionate risk-reduction measures. For those who become dependent on drugs, treatment-on-demand is a more effective intervention than criminalization. In lieu of a legal, safe supply of substances, drug checking can identify adulterants like fentanyl. Peer support is so successful in transforming emotionally challenging experiences that Denvers first responders and police officers will soon be trained in the method as an alternative to criminalization or sedation.

Last year, Oregon became the first US state to decriminalize the possession of most drugs and to create a legal system for supervised psilocybin experiences. California, Vermont and Hawaii are actively considering new legal frameworks for psychedelics; Texas is directing state funding to research. In the face of an epidemic of veteran suicide, the US veterans administration is hosting small psychedelic-assisted therapy trials. Members of Congress from both sides of the aisle support federal funding. Lawmakers, regulators, funders, insurance providers and therapists who take a clear-eyed look at the research may be surprised to find their fears dissolving.

MAPS recognizes that the people who are most marginalized by society are often those who are most traumatized, have least access to a diagnosis and even less access to adequate treatment. MAPS is working with researchers around the world to facilitate studies of psychedelic-assisted therapy with refugees, transgender communities, first responders exhausted by Covid, people of color subjected to racial trauma and more. We envision a day when psychedelics will be more than a last-ditch treatment: they will be a catalyst for mass mental health.

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Psychedelics can change humanity for the better. Its time to unlock their power - The Guardian

New study finds ‘microdosing’ psychedelics can be effective in treating anxiety, depression | TheHill – The Hill

A new study is adding to the growing body of research suggesting the use of certain hallucinogens can help treat people battling mental health disorders.

A study recently published in Nature: Scientific Reports found the use of small doses of psychedelics such as psilocybin, the active ingredient found in magic mushrooms, or LSD resulted in a reduction of anxiety and depression symptoms among participants.

The international study led by the University of British Columbia Okanagan (UBCO) included more than 8,500 people from 75 countries who used an anonymous self-reporting system. About half of the participants were "microdosing," or consuming very low quantities of psychedelics, while half were not.

In comparing microdosers and non-microdosers, there was a clear association between microdosing and fewer symptoms of depression, anxiety and stresswhich is important given the high prevalence of these conditions and the substantial suffering they cause, Joseph Rootman, UBCO doctoral student and the studys lead author, said in a statement.

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Researchers also said the study is the first to examine the practice of combining small doses of psychedelics with other substances such as niacin, lions mane mushrooms and cacao.

Over the past several years, numerous studies have shown small doses of psychedelics psilocybin specifically have resulted in improvements in the levels of depression among participants.

A 2016 study looked at whether the drug could help with symptoms of cancer-related depression and anxiety. A group of cancer patients were given a single dose of synthetic psilocybin and reported their anxiety and depression symptoms eased. A 2020 follow-up study found many participants were still feeling the positive effects of the treatment years later.

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New study finds 'microdosing' psychedelics can be effective in treating anxiety, depression | TheHill - The Hill

Psychedelics stocks were all the rage a year ago. What happened? – The Globe and Mail

A blister pack of Ketamine lozenges at the psychedelic therapy clinic in Toronto on Aug. 28, 2020.COLE BURSTON/AFP/Getty Images

It was barely a year ago that psychedelics stocks were all the rage among investors, drawn to grandiose promises by companies that drugs such as LSD and magic mushrooms could produce game-changing treatments for anxiety, depression and addiction.

But that investor euphoria peaked in March, 2021. Since then, despite a handful of promising clinical trials, and a growing number of U.S. states introducing bills to decriminalize psychedelic substances, shares of many psychedelics companies have performed poorly, sharply declining in value over the past six months.

This disconnect, analysts say, can be blamed primarily on retail investors who seemed to associate psychedelics companies with sales-driven cannabis producers, rather than thinking of them as biotech firms that will take years to begin generating revenue.

While the performance of Canadian cannabis companies hinged on consumer demand for a product that became legal for recreational use in October, 2018, most psychedelics companies are involved in early-stage scientific research on how specific chemical compounds that make up drugs such as ketamine, LSD and MDMA could potentially be used in treating mental-health conditions.

For the biggest companies in the space, their business model is fundamentally a biotech one, explained Michael Freeman, a health care sector analyst with Raymond James Financial. These are companies that will spend years running randomized, controlled, clinical trials of psychedelic molecules to determine their efficacy. It is a very different value proposition than cannabis.

Field Trip Health raises largest financing in Canada for a psychedelics company

The shiny new object: Despite being illegal, retail investor rush to psychedelics resembles euphoria around cannabis

The lacklustre performance of psychedelics stocks is clearly evident in how the worlds first psychedelics exchange-traded fund a basket of stocks comprising more than 20 companies in the sector has fared. Since its launch in January, the Horizons Psychedelics Stock Index ETF has plunged by 36 per cent.

Although the index is rebalanced quarterly, it was initially weighted heavily in favour of some of the most well-known psychedelics companies, such as MindMed Inc., and Compass Pathways Inc. The share prices of both companies have dipped by more than 40 per cent since the height of investor excitement in early 2021.

People saw it as a get-rich-quick industry, but as the months went by investors realized this is nothing like cannabis. These are heavily regulated substances that have to go through many clinical trials, so you would want to stay with the company to reap the benefits, said Tania Gonsalves, an analyst with Toronto-based Canaccord Genuity Inc.

MindMed was heavily promoted and championed by Shark Tanks Kevin OLeary, who famously told Business Insider in November, 2020, that investors burned by bad bets on cannabis startups should not be afraid to gamble on psychedelics.

The New York-based company specializes in developing molecules of LSD, MDMA and psilocybin the hallucinogenic chemical in certain mushrooms for the treatment of depression.

It was the first psychedelics company to go public (in March, 2020), on Torontos NEO Exchange, and now trades on Nasdaq as well.

But while MindMed shares have gained a whopping 425 per cent since the company made its public debut at 40 cents, they have declined by almost 50 per cent since the psychedelics market peaked in February, around the time Horizons launched its psychedelics ETF.

Unfortunately we launched the ETF six months too late, admitted Steve Hawkins, chief executive officer of Toronto-based Horizons ETFs Management Inc. A lot of the companies in our portfolio are up triple digits since they went public. But on a six-month basis, many of them are down.

Mr. Hawkins told The Globe and Mail that Horizons has had to consistently rebalance its psychedelics portfolio because the sector is volatile. These companies are all over the place. All it takes is one piece of news whether it be fact or fiction to create significant volatility with the underlying portfolio.

On Nov. 9, Britain-based Compass Pathways announced much-anticipated results of a 233-patient study of the use of psilocybin in treatment-resistant depression, finding that the patient group receiving the highest dose of COMP360 (a molecular derivative of psilocybin) exhibited significant reduction in depression symptoms compared with those who received a lower dose.

Analysts covering the company ranked the result as neutral to positive. Yet Compass shares sank roughly 20 per cent after the news, as many investors seemed to determine it was the right time to exit the stock.

Mr. Freeman said the reaction is typical in the psychedelics space, which is dominated by retail investors.

Proper biotech investors make decisions based on when a company does data readouts, meaning, when [companies] have tangible results from a clinical trial that gets them to a new phase to proceed in research, Mr. Freeman explained. So biotech stocks generally move either up or down depending on which stage in the research process investors want to take their profit.

Andrew Partheniou of Stifel Financial Inc., another analyst who covers psychedelics companies, said he was surprised at how the market reacted to Compasss clinical trial results, which he deemed to be positive. I think for retail investors, it might have brought up questions on how well Compass could actually scale its therapies and what its real addressable market might be like.

Raj Lala, an investment manager and CEO of Evolve ETFs, a competitor to Horizons, said he chose not to launch a psychedelics ETF because he could not see the long-term growth potential of psychedelics companies. It feels like a fad, Mr. Lala added, drawing a comparison to the cannabis sector. Evolve had launched two cannabis ETFs, but terminated them less than two years later, after they lost more than 50 per cent of their value. We did not have a good experience in that space, he admitted.

But Mr. Hawkins of Horizons is in psychedelics for the long haul. This is early stage biotech investing, there will be hits and misses. Were going through a lull period right now, but Im hoping investors will understand there is significant long-term potential in these drugs.

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Psychedelics stocks were all the rage a year ago. What happened? - The Globe and Mail

I have ADHD and was scared of psychedelics. Then I found myself eating magic truffles … – The Guardian

If you had asked me pre-pandemic if I would ever touch psychedelics, I would have said absolutely not. The speed of my brain is literally my only skill. As a standup comedian and podcaster, I can walk out on stage with absolutely nothing in my head and riff with an audience for an hour if I need to which I know seems like a superpower to others while ordinary powers, such as the ability to do my laundry every week, elude me.

I was recently diagnosed with ADHD first in the green room by other comedians, then by a doctor. It seems that a lot of us comics have it. I guess its a job you can do if you are not neurotypical, because you see the world from an unusual angle and there is very little admin. I often see comics on Facebook posting: Ive just got Peckham in my diary for tonight; am I meant to be doing a gig for anyone there?

I am sure there are many people with ADHD who have trained themselves to be great in office environments, but I suspect its too late for me, so I really need to hold on to that talk-fast-and-mind-map skill. That is why at music festivals I always said no to anything that might change my brain chemistry. I had resigned myself to the fact that I would never see the face of God in a cloud, or myself as a baby cat on the ocean floor.

So, on one level, I was genuinely surprised to find myself consuming a cup of magic truffles at an entirely legal therapeutic retreat in Amsterdam. (These are a lot like magic mushrooms, but grow beneath the ground, rather than above.) At the same time, somehow it felt inevitable. The safe, repetitive domesticity of lockdown had made me face my demons and seek therapy, but it had also made me hungry for sensation and risk.

A friend had phoned me and told me that she had taken a trip to the desert and done ayahuasca. She said it had healed so many of her traumatised wounds with visionary reconciliations and not slowed down her speedy, creative brain at all. She said I should do it but I had to wait till I got the call. I said: Babe, you are literally calling me now this is the call. Her thinking was that it couldnt be a phone call it had to be more spiritual than that. I started looking for signs. They are there if you Google retreats in Amsterdam. You can get the Eurostar there now, you know.

But ayahuasca wasnt on the cards for me. Lars, the shaman at the retreat that I settled for, said it was probably better to do truffles if youve have never done any psychedelics at all. He handed me a little bowl of truffles and told me to eat them all, then to lie down in the next room as soon as I needed to. I assumed I would be in a field staring at trees, but this is a therapeutic dose under supervision. You cant walk or talk.

Soon I was in a room alone under a duvet cover covered in dancing flowers. The wardrobe in the corner was animated like something out of Beauty and the Beast. I thought I would close my eyes to get away from it for a minute, but that made the visions much more intense. I saw the whole of the 60s in an hour. I understood every album cover I had ever seen. Not long after, I was in the womb and then the afterlife.

It didnt feel scary at all it was like I had gone back to the ground and become part of the energy of the world. Still alive, but rested, without the constant demands of email. I saw people in my life in new and revelatory ways, as well as the first act of feminism in the rebellion of the Garden of Eden. When Lars checked on me, I said: I dont know if youre real or not, but this is how religions are started, isnt it? He said: Yes.

I came out of it after four hours. My brain was as fast as ever, but at some kind of new and unusual peace. My therapist in New York reassures me that much research is going on around the world into the benefits of these natural substances for trauma sufferers.

Now, I have a gig in Peckham tonight. Does anyone know where it is?

Deborah Frances-White is a comedian, writer and the host of the podcast The Guilty Feminist. Arwa Mahdawi is away

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I have ADHD and was scared of psychedelics. Then I found myself eating magic truffles ... - The Guardian

Psyence Group Invited as First Psychedelic Company to present at the 15th-Annual Global Wellness Summit – GlobeNewswire

TORONTO, Nov. 26, 2021 (GLOBE NEWSWIRE) -- Psyence Group Inc. (CSE: PSYG | OTCQB: PSYGF) (Psyence or the Company), a life science biotechnology company with a focus on natural psychedelics in mental health and well-being, will break new ground as the first psychedelic company invited to speak at the 15th Annual Global Wellness Summit, a gathering of international leaders in the $4.5 trillion global wellness economy.1 Meeting in Boston November 30 to December 3, 2021, thesummit includes doctors, activists, and health care executives from research organizations that include Harvard, Massachusetts Institute of Technology (MIT), Cleveland Clinic and elsewhere.

Psyences Head of Corporate Social Responsibility, Mary-Elizabeth Gifford, will host an in-person keynote conversation with Rick Doblin, PhD, Founder and Executive Director of the Multidisciplinary Association for Psychedelic Studies (MAPS) on the future of Psychedelics and Healing.

A psychedelic researcher and activist, Doblin isrecognized for his work de-stigmatizing psychedelics through evidence-based scientific research. His organization,MAPS, is sponsoring Phase 3 clinical trials of MDMA-assisted therapy for PTSD.

Mary-Elizabeth Gifford, chair of the non-profit Global Wellness Institute's Psychedelics & Healing Initiative, leads Corporate Social Responsibility for the Psyence Group, where she works to democratize responsible psychedelic and nature-based solutions for mental health and wellness that also help heal and strengthen the wider community. The Keynote Conversation with Gifford and Doblin takes place December 1st, 2021, at 4:10pm EST. This event is in person and registration can be accessed virtually at https://www.globalwellnesssummit.com.

ABOUT PSYENCE GROUP: http://www.psyence.com

Psyence is a public life science biotechnology company listed on the Canadian Securities Exchange and (CSE: PSYG) and quoted on the OTCQB (OTCQB: PSYGF), with a focus on natural psychedelics. Psyence works with natural psilocybin products for the healing of psychological trauma and its mental health consequences in the context of palliative care.

Our name Psyence combines the wordspsychedelicandscienceto affirm our commitment to producing psychedelic medicines developed through evidence-based research.Informed by nature and guided by science, we built and operate one of the worlds first federally licensed commercial psilocybin mushroom cultivation and production facilities.

Our team brings international experience in both business and science and includes experts in mycology, neurology, palliative care, and drug development. We work to develop advanced natural psilocybin products for clinical research and development. We have entered into a long term joint venture to launch mushroom-based mental wellness focused nutraceutical products, the GOODMIND collection, to support improved focus, calm, and sleep.

Our key divisions, Psyence Production, Psyence Therapeutics, and Psyence Function, anchor an international collaboration, with operations in Canada, the United Kingdom, Jamaica, South Africa and a presence in the United States and Australia.

Contact Information:Lisa-Marie Iannitelli, Investor RelationsEmail:ir@psyence.com

Media Inquiries: media@psyence.comGeneral Information: info@psyence.com

1 https://globalwellnessinstitute.org/press-room/statistics-and-facts/; https://www.forbes.com/sites/forbesbusinessdevelopmentcouncil/2019/10/14/why-the-wellness-business-is-booming-and-how-to-succeed-in-the-industry/?sh=731f0b7c41aa

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Psyence Group Invited as First Psychedelic Company to present at the 15th-Annual Global Wellness Summit - GlobeNewswire