12345...102030...


Psoriasis – What is Psoriasis? Basic Symptoms and Types

What Is Psoriasis?

Unpredictable and irritating, psoriasis is one of the most baffling and persistent of skin disorders. It’s characterized by skin cells that multiply up to 10 times faster than normal. As underlying cells reach the skin’s surface and die, their sheer volume causes raised, red plaques covered with white scales. Psoriasis typically occurs on the knees, elbows, and scalp, and it can also affect the torso, palms, and soles of the feet.

The symptoms of psoriasis vary depending on the type you have. Some common symptoms for plaque psoriasis — the most common variety of the condition — include:

Psoriasis can also be associated with psoriatic arthritis, which leads to pain and swelling in the joints. The National Psoriasis Foundation estimates that between 10% to 30% of people with psoriasis also have psoriatic arthritis.

Other forms of psoriasis include:

Pustular psoriasis , characterized by red and scaly skin on the palms of the hands and/or feet with tiny pustules

Guttate psoriasis, which often starts in childhood or young adulthood, is characterized by small, red spots, mainly on the torso and limbs. Triggers may be respiratory infections, strep throat, tonsillitis, stress, injury to the skin, and use of anti-malarial and beta-blocker medications.

Inverse psoriasis, characterized by bright red, shiny lesions that appear in skin folds, such as the armpits, groin area, and under the breasts

Erythrodermic psoriasis, characterized by periodic, fiery redness of the skin and shedding of scales in sheets; this form of psoriasis, triggered by withdrawal from a systemic psoriasis treatment, severe sunburn, infection, and certain medications, requires immediate medical treatment, because it can lead to severe illness.

People who suffer from psoriasis know that this uncomfortable and at times disfiguring skin disease can be difficult and frustrating to treat. The condition comes and goes in cycles of remissions and flare-ups over a lifetime. While there are medications and other therapies that can help to clear up the patches of red, scaly, thickened skin that are the hallmark of psoriasis, there is no cure.

A variety of factors — ranging from emotional stress and trauma to streptococcal infection — can cause an episode of psoriasis. Recent research indicates that some abnormality in the immune system is the key cause of psoriasis. As many as 80% of people having flare-ups report a recent emotional trauma, such as a new job or the death of a loved one. Most doctors believe such external stressors serve as triggers for an inherited defect in immune function.

Injured skin and certain drugs can aggravate psoriasis, including certain types of blood pressure medications (like beta-blockers), the anti-malarial medication hydroxychloroquine, and ibuprofen (Advil, Motrin, etc.).

Psoriasis tends to run in families, but it may be skip generations; a grandfather and his grandson may be affected, but the child’s mother never develops the disease. Although psoriasis may be stressful and embarrassing, most outbreaks are relatively harmless. With appropriate treatment, symptoms generally subside within a few months.

SOURCES: National Institute of Arthritis and Musculoskeletal and Skin Disease. National Psoriasis Foundation. The Psoriasis Foundation. American Academy of Dermatology.

See the rest here:

Psoriasis – What is Psoriasis? Basic Symptoms and Types

Psoriasis – Overview – Mayo Clinic

In psoriasis, the life cycle of your skin cells greatly accelerates, leading to a buildup of dead cells on the surface of the epidermis.

Psoriasis is a common skin condition that speeds up the life cycle of skin cells. It causes cells to build up rapidly on the surface of the skin. The extra skin cells form scales and red patches that are itchy and sometimes painful.

Psoriasis is a chronic disease that often comes and goes. The main goal of treatment is to stop the skin cells from growing so quickly.

There is no cure for psoriasis, but you can manage symptoms. Lifestyle measures, such as moisturizing, quitting smoking and managing stress, may help.

Psoriasis care at Mayo Clinic

Go here to read the rest:

Psoriasis – Overview – Mayo Clinic

Psoriasis | Psoriatic Arthritis | MedlinePlus

Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. You usually get the patches on your elbows, knees, scalp, back, face, palms and feet, but they can show up on other parts of your body. Some people who have psoriasis also get a form of arthritis called psoriatic arthritis.

A problem with your immune system causes psoriasis. In a process called cell turnover, skin cells that grow deep in your skin rise to the surface. Normally, this takes a month. In psoriasis, it happens in just days because your cells rise too fast.

Psoriasis can be hard to diagnose because it can look like other skin diseases. Your doctor might need to look at a small skin sample under a microscope.

Psoriasis can last a long time, even a lifetime. Symptoms come and go. Things that make them worse include

Psoriasis usually occurs in adults. It sometimes runs in families. Treatments include creams, medicines, and light therapy.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Original post:

Psoriasis | Psoriatic Arthritis | MedlinePlus

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

Most parents arent afraid to show their children affection in public. But Arizona mom Ashley Nagy says she makes a special point to kiss and cuddle her 19-month-old daughter Charlie when the two are out and about because Charlie suffers from psoriasis , a chronic autoimmune disease that speeds up the growth of skin cellsand Nagy says she wants to make sure people know it isnt contagious .

For the most part, Nagy tells SELF that strangers on the playground have been inquisitive, often simply asking, “What does she have? But some of the “ruder comments are Oh my goshyour daughter is sunburned . I cant believe you have her out in public or I dont want to see that, she says. She’s also noticed that other kids or mothers will stare at Charlie, and some parents will even keep their kids away from her daughter for fear of catching psoriasis. When that happens, I just pick her up and kiss her neck or cheeks, or rub her arm, Nagy says. Its my way of not confronting them, but showing that shes not contagious.

Nagy says that shes grateful that Charlie is so young that she doesnt realize whats happening. I just hope that Ive done a good [enough] job that when she starts to realize shes different, she has enough confidence to face people and not take what they say to heart, she says. Youre going to have random people who are mean and cruelyou cant control them, but you can control how you react to them.

About 7.5 million people in the U.S. have psoriasis, according to the American Academy of Dermatology . The condition is largely caused by genetics, but having genes associated with psoriasis doesnt mean youll actually develop the condition. In fact, at least 10 percent of people inherit one or more of the genes that can eventually lead to psoriasis, according to the National Psoriasis Foundation , but only 2 to 3 percent of people actually develop the disease.

That’s because, in order to actually develop the condition, you need to have a combination of the genes that cause it and to be exposed to particular triggers, such as stress, an injury to the skin (e.g. a sunburn), allergies , diet, an infection, certain medications (including lithium and the heart medication quinidine), and even the weather, the NPF says.

Although people of any age can have the condition, its primarily seen in adults. Charlies symptoms first began soon after she was born, Nagy says, and she was diagnosed with psoriasis when she was 4 months old. People were shocked at how young she was when she was diagnosed, Nagy says.

People who suffer from psoriasis may experience flare-ups in which they have the characteristic red, itchy, scaly skin patches, but in between flare-ups their skin may look normal. Charlie is now on an anti-inflammatory diet that also avoids gluten and dairy to help try to ward off flare-ups. That seems to help a lot, Nagy says. But Charlie still suffers from flare-ups, which cause her to develop red patches all over her body that itch. Shell point to her marks and say, Ouchies, ouchies, Nagy says. When Charlie has a flare-up, shes itchy and uncomfortable all day, and has trouble sleeping at night. But, when shes not suffering from a flare-up, her condition doesnt really impact her, Nagy says.

Psoriasis is caused by inflammation and not an infection, so it’s not contagious at all, Gary Goldenberg , M.D., assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai Hospital, tells SELF. Luckily, there are several treatments for psoriasis, and the best one for each patient depends on how severe their symptoms are. Mild psoriasis can be treated with creams and lotions, or over-the-counter medication like steroid creams, Dr. Goldenberg says.

Petrolatum-based moisturizers are often the most helpful because they form a protective seal over the skin to keep it hydrated while also minimizing the appearance of flakes on the skin, Joshua Zeichner , M.D., a New York City-based board-certified dermatologist, tells SELF. People can also develop psoriasis on their scalp, which can be treated with over-the-counter medicated shampoos, such as Neutrogena T/Gel shampoo , Dr. Zeichner says.

For people with more severe cases, there are biologic immune-modifying medications that alter the immune system reactions that lead to psoriasis, Cynthia Bailey, M.D., a diplomate of the American Board of Dermatology and president and CEO of Advanced Skin Care and Dermatology Inc. , tells SELF. That includes infliximab, for instance, which reduces the effects of substances in the body that can cause inflammation.

While it can be treated, it cannot be cured, Dr. Goldenberg says. Some patients can experience a remission of their disease that can last years, but this is unpredictable and rare. In most cases, patients need to keep treating their psoriasis for the rest of their lives to avoid flare-ups. We can help reduce signs of the disease on the skin, however the rash often reappears if you stop treating it, Dr. Zeichner says.

If psoriasis runs in your family, you can develop it at any point in your life, Dr. Bailey says, and its more likely to show up as you age. Although we don’t know exactly why, it “probably has something to do with the process of aging and how it impacts the immune system, Dr. Bailey says. If psoriasis runs in your family, she recommends limiting your alcohol intake, maintaining a healthy diet, and getting regular exercise to lower your odds of developing the condition.

Charlie used to have to see her doctor every two weeks to have her blood drawn for testing and monitoring purposes, Nagy says, but now she goes to the doctor every four months for her condition. Weve been keeping it at bay with her diet and bath regimen, she says. Nagy has started a GoFundMe to help pay for her daughters medical bills. A lot of people see ads on TV for psoriasis medications, but they dont actually know what psoriasis is, Nagy says. I want them to see what it looks like firsthandand to show that its not contagious.

Related:

You May Also Like: This Professional Ballerina With Vitiligo Will Change How You Think About Beauty

Read the rest here:

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

NASH FibroSure Test Useful for Tracking Fibrosis in Psoriasis – MedPage Today

Noninvasive tests may be used as an alternative to liver biopsy and imaging for monitoring hepatic fibrosis in psoriasis patients who are taking methotrexate sodium, researchers reported.

In a small single-institution cohort study, 54 out of 69 patients (78.3%) who underwent NASH FibroSure testing prior to starting methotrexate sodium therapy had elevated steatosis scores and 27.5% had elevated fibrosis scores, according to Clayton Green, MD, PhD, of Marshfield Clinic in Marshfield, Wisc., and colleagues.

“Our results do not suggest that a liver biopsy can be entirely replaced by the NASH FibroSure test,” they wrote in JAMA Dermatology. “They do, however, support the idea that the number of liver biopsies can be significantly reduced by the use of noninvasive tests such as the NASH FibroSure.”

While there are several noninvasive proprietary tests available for monitoring the risk of progression of hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD), the FibroSure test is the most widely adopted test for evaluating the hepatotoxic effects of methotrexate sodium therapy.

The model is a semi-quantitative test that calculates the degree of hepatic fibrosis using computational algorithms to analyze serum levels of aminotransferases, 2- macroglobulins, haptoglobin, apolipoprotein A1, cholesterol, transpeptidase, glucose, and triglycerides, as well as age, sex, height, and weight. Its inclusion of height and weight are a unique opportunity to account for the role of BMI in the progression of steatosis to fibrosis, the researchers noted.

Green’s group conducted a descriptive retrospective analysis of 107 patients with psoriasis treated with methotrexate sodium therapy. All patients underwent NASH FibroSure testing from 2007 to 2013 at a single dermatology referral center. Of this cohort, 107 (57 women) were eligible for correlation analysis.

Among the patients who underwent NASH FibroSure testing during methotrexate therapy, the cumulative methotrexate sodium therapy dose corresponded to a statistically significant association of a higher NASH FibroSure hepatic fibrosis score in women (Spearman =0.21, P=0.02) but not in men. The correlation for women remained significant even after correcting for patients who had multiple NASH FibroSure tests, the researchers reported.

Green’s group also found a statistically significant correlation between a BMI of 28 or more and worsening fibrosis scores in women (Spearman =0.2, P=0.03), suggesting that obesity influenced the progression of fibrosis scores in women.

No significant correlations were seen between ages 65 and up and worsening of hepatic fibrosis scores with cumulative methotrexate sodium therapy dose. Additionally, there were no differences between men and women in terms of prevalence of a BMI of 28 or more, diabetes, age older than 65, or chronic kidney disease.

“Although our study design does not allow us to examine the contribution of methotrexate sodium therapy to worsening fibrosis scores, our results provide support for the application of serologic tests for the progression of NAFLD to patients with psoriasis,” the authors stated.

They explained that further analysis of differences between men and women in the progression of hepatic fibrosis by methotrexate sodium therapy dose could lead to improved treatment and monitoring recommendations.

They also noted the need for a prospective, randomized, multi-institutional analysis of NASH FibroSure and liver biopsies for patients with psoriasis receiving methotrexate sodium versus other treatments. This should specifically be a larger cohort of men and women with different racial and ethnic backgrounds, they added.

A leading study limitation was the use of a mathematical model that generated a risk score for hepatic fibrosis without offering an actual measure of fibrosis. Additionally, the cohort was uncontrolled and the change in fibrosis scores or the progression of NAFLD in patients with psoriasis remains unknown.

The study was funded by the Marshfield Clinic Resident Research Program.

Green disclosed funding from T2 Biosystems.

2017-08-23T11:00:00-0400

Read more:

NASH FibroSure Test Useful for Tracking Fibrosis in Psoriasis – MedPage Today

Encore makes pipeline play, licensing psoriasis drug from Dr. Reddy’s – FierceBiotech

Encore Dermatology, formed two years ago as a vehicle for three ex-Valeant products, has picked upa late-stage pipeline drug via a deal with India’s Dr. Reddy’s Laboratories.

The Malvern, Pennsylvania, company says it has licensed a steroid candidate developed by Dr. Reddy’s Promius Pharma subsidiary that has passed phase 3 testing in adults with moderate to severe plaque psoriasis and could claim U.S. approval within weeks.

Encore is paying up to $32.5 million for development, manufacturing and commercialization rights to the drug, a topical corticosteroid called DFD-06 that is administered twice daily as a cream and is also in phase 2 testing for psoriasis in children and adolescents.

If approved, the drug will slot into its portfolio alongside dermatologic creams Hylatopic and Tetrixacquired from Valeant along with acne drug BenzEFoam in 2015as well as low-potency corticosteroid cream Tridesilon (desonide) which was licensed from Perrigo and launched earlier this year for skin conditions such as atopic dermatitis.

Dr. Reddy’s has been funneling 40% of its R&D spend into biosimilars and proprietary medicinesprimarily for the U.S. marketas it tries to move beyond its heartlands in generic small-molecule drugs that have been hampered of late by regulatory compliance problems at manufacturing facilities.

So far, that drive has focused on improved formulations of established drug molecules and has resulted in two drug launches in the U.S.Zembrace Symtouch, an injectable form of sumatriptan for migraine and Sernivo, a spray formulation of the steroid drug betamethasone. The company has targeted sales of $500 million for its proprietary business within the next five years.

We believe Encore and its management team are well positioned to realize the full potential of this asset DFD-06,” said Anil Namboodiripad, Ph.D., president of Promius Pharma.

“We look forward to obtaining NDA approval this fall, enabling Encore’s management team to quickly deliver this product to the providers and their patients,” he added.

Continue reading here:

Encore makes pipeline play, licensing psoriasis drug from Dr. Reddy’s – FierceBiotech

Encore Dermatology gets rights to psoriasis drug DFD-06 – The Pharma Letter (registration)

Dr Reddys Laboratories, through its wholly-owned US subsidiary Promius Pharma, has out-licensed the

To continue reading this article and to access exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space you need to be logged into the site and have an active subscription or trial subscription. Please loginorsubscribe in order to continue reading. Claim a week’s trial subscriptionby signing up for free today and receive our daily pharma and biotech news bulletin free of charge, forever.

Continued here:

Encore Dermatology gets rights to psoriasis drug DFD-06 – The Pharma Letter (registration)

Dr. Reddy’s sells off psoriasis candidate in out-licensing deal … – BioPharma Dive

Dive Brief:

Dr Reddy’s has completed Phase 3 studies, manufactured registration batches, and made preparations for a New Drug Application (NDA) filing for DFD-06, but has chosen to license the drug out rather than pursue commercialization in house.

“We look forward to obtaining NDA approval this fall, enabling Encores management team to quickly deliver this product to the providers and their patients.” says Anil Namboodiripad, SVP, Proprietary Products, and president, Promius Pharma.

Dr. Reddy’s has had a challenging year. Shares in the drugmaker began a month-long slide following the announcement of its first quarter 2018 results in July 2017, which recorded a 6% decline in revenues and a 53% fall in profits year-on-year. The lackluster results were due, in part, to price erosion from U.S. customer consolidation and a lower contribution from U.S. product launches.

The Indian drugmaker has also had a tough time with manufacturing, running afoul of stepped-up oversight from the Food and Drug Administration. In April, the regulator completed an audit of the company’s Srikakulam-based production site, flagging points where the site fell shortof regulatory standards. This inspection resulted in a Form 483, adding to similar letters issued to the company’s Miryalguda and Bachupally sites this year.

See original here:

Dr. Reddy’s sells off psoriasis candidate in out-licensing deal … – BioPharma Dive

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

Most parents arent afraid to show their children affection in public. But Arizona mom Ashley Nagy says she makes a special point to kiss and cuddle her 19-month-old daughter Charlie when the two are out and about because Charlie suffers from psoriasis , a chronic autoimmune disease that speeds up the growth of skin cellsand Nagy says she wants to make sure people know it isnt contagious .

For the most part, Nagy tells SELF that strangers on the playground have been inquisitive, often simply asking, “What does she have? But some of the “ruder comments are Oh my goshyour daughter is sunburned . I cant believe you have her out in public or I dont want to see that, she says. She’s also noticed that other kids or mothers will stare at Charlie, and some parents will even keep their kids away from her daughter for fear of catching psoriasis. When that happens, I just pick her up and kiss her neck or cheeks, or rub her arm, Nagy says. Its my way of not confronting them, but showing that shes not contagious.

Nagy says that shes grateful that Charlie is so young that she doesnt realize whats happening. I just hope that Ive done a good [enough] job that when she starts to realize shes different, she has enough confidence to face people and not take what they say to heart, she says. Youre going to have random people who are mean and cruelyou cant control them, but you can control how you react to them.

About 7.5 million people in the U.S. have psoriasis, according to the American Academy of Dermatology . The condition is largely caused by genetics, but having genes associated with psoriasis doesnt mean youll actually develop the condition. In fact, at least 10 percent of people inherit one or more of the genes that can eventually lead to psoriasis, according to the National Psoriasis Foundation , but only 2 to 3 percent of people actually develop the disease.

That’s because, in order to actually develop the condition, you need to have a combination of the genes that cause it and to be exposed to particular triggers, such as stress, an injury to the skin (e.g. a sunburn), allergies , diet, an infection, certain medications (including lithium and the heart medication quinidine), and even the weather, the NPF says.

Although people of any age can have the condition, its primarily seen in adults. Charlies symptoms first began soon after she was born, Nagy says, and she was diagnosed with psoriasis when she was 4 months old. People were shocked at how young she was when she was diagnosed, Nagy says.

People who suffer from psoriasis may experience flare-ups in which they have the characteristic red, itchy, scaly skin patches, but in between flare-ups their skin may look normal. Charlie is now on an anti-inflammatory diet that also avoids gluten and dairy to help try to ward off flare-ups. That seems to help a lot, Nagy says. But Charlie still suffers from flare-ups, which cause her to develop red patches all over her body that itch. Shell point to her marks and say, Ouchies, ouchies, Nagy says. When Charlie has a flare-up, shes itchy and uncomfortable all day, and has trouble sleeping at night. But, when shes not suffering from a flare-up, her condition doesnt really impact her, Nagy says.

Psoriasis is caused by inflammation and not an infection, so it’s not contagious at all, Gary Goldenberg , M.D., assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai Hospital, tells SELF. Luckily, there are several treatments for psoriasis, and the best one for each patient depends on how severe their symptoms are. Mild psoriasis can be treated with creams and lotions, or over-the-counter medication like steroid creams, Dr. Goldenberg says.

Petrolatum-based moisturizers are often the most helpful because they form a protective seal over the skin to keep it hydrated while also minimizing the appearance of flakes on the skin, Joshua Zeichner , M.D., a New York City-based board-certified dermatologist, tells SELF. People can also develop psoriasis on their scalp, which can be treated with over-the-counter medicated shampoos, such as Neutrogena T/Gel shampoo , Dr. Zeichner says.

For people with more severe cases, there are biologic immune-modifying medications that alter the immune system reactions that lead to psoriasis, Cynthia Bailey, M.D., a diplomate of the American Board of Dermatology and president and CEO of Advanced Skin Care and Dermatology Inc. , tells SELF. That includes infliximab, for instance, which reduces the effects of substances in the body that can cause inflammation.

While it can be treated, it cannot be cured, Dr. Goldenberg says. Some patients can experience a remission of their disease that can last years, but this is unpredictable and rare. In most cases, patients need to keep treating their psoriasis for the rest of their lives to avoid flare-ups. We can help reduce signs of the disease on the skin, however the rash often reappears if you stop treating it, Dr. Zeichner says.

If psoriasis runs in your family, you can develop it at any point in your life, Dr. Bailey says, and its more likely to show up as you age. Although we don’t know exactly why, it “probably has something to do with the process of aging and how it impacts the immune system, Dr. Bailey says. If psoriasis runs in your family, she recommends limiting your alcohol intake, maintaining a healthy diet, and getting regular exercise to lower your odds of developing the condition.

Charlie used to have to see her doctor every two weeks to have her blood drawn for testing and monitoring purposes, Nagy says, but now she goes to the doctor every four months for her condition. Weve been keeping it at bay with her diet and bath regimen, she says. Nagy has started a GoFundMe to help pay for her daughters medical bills. A lot of people see ads on TV for psoriasis medications, but they dont actually know what psoriasis is, Nagy says. I want them to see what it looks like firsthandand to show that its not contagious.

Related:

You May Also Like: This Professional Ballerina With Vitiligo Will Change How You Think About Beauty

See the article here:

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

Psoriasis: New Treatments Help Millions Manage Common Skin Condition – Newsmax

For years, psoriasis suffers have battled patches of rough, reddened, and intensely itchy skin that can cause pain as well embarrassment, with little hope of relief.

But major breakthroughs have been logged in the treatment of this potentially debilitating disorder that affects almost 10 million Americans, including small children. And if you are suffering from the disease, its time to take action.

To spotlight the treatments that have emerged in recent years, the National Psoriasis Foundation is observing National Psoriasis Action month in August.

The NPF Foundation wants to spread the word that there have been tremendous advancements in the number of treatment options for people living with the condition. The NPF has even launched a website to educate patients, caregivers and health care professionals about the resources to treat psoriatic disease.

Throughout August, people impacted by psoriasis can participate in interactive quizzes that will help them better understand and manage their disease, Dr. Michael Siegel, Ph.D, vice president of Research Programs at the NPF tells Newsmax Health.

Psoriasis often develops between the ages of 15 and 35, but it can develop at any age. While scientists do not know exactly what causes psoriasis, it is known that the immune system and genetics play major roles in its development.

Usually, something triggers the condition to flare. The skin cells in people with psoriasis grow at an abnormally fast rate, which leads to painful lesions on the body.

The genetic link is clear, says Siegal.

If one parent has psoriasis, there is about a 10 percent chance of a child contracting it. If both parents have psoriasis, the chance increases to 50 percent, he notes.

Dr. Kenneth Beer, associate clinical professor of dermatology at the University of Miami, tells Newsmax Health that the No. 1 myth about psoriasis is that it is just dry skin.

Its far more than that, he says. Psoriasis is an immune disease in which the body stimulates growth of skin cells in an abnormal way. It is largely genetic and may be associated with stress, infection medication or a range of other issues. In addition to affecting the skin, it can frequently affect the joints of the body.

Another myth is that the condition is contagious. Not so, says Beer. And while it is not curable at this point in time, it is manageable and treatable. But if you dont take care of your psoriasis, it can lead to serious medical conditions.

According to the Mayo Clinic, people with psoriasis are at a great risk for Type 2 diabetes as well as vision problems and heart disease. About 30 percent of people who have psoriasis will develop psoriatic arthritis, according to the NPF.

Reality TV star Kim Kardashian revealed that she suffers from the condition and that stress plays a key role in her flare-ups of psoriasis. Two-time Grammy winning songstress LeAnn Rimes kept her struggle hidden until 2008 when she decided to open up about her experience as part of the Stop Hiding, Start Living awareness campaign sponsored by Abbott, which makes the psoriasis drug, Humira.

Other celebs with psoriasis include comedian Jon Lovitz and Leave it to Beaver star Jerry Mathers, who admits that the condition is no laughing matter.

Siegel says that treating psoriasis involves good disease management and paying attention overall health.

With advances in the number of treatment options available today for people living with psoriasis its easier than ever to treat the condition, he says. The biggest breakthrough came 10 years ago with the introduction of injectable biologics which changed the lives of patients and their providers.

By targeting specific pathways in the immune system, these biologics have demonstrated remarkable outcomes in clinical trials. Moving forward, scientists are likely to reveal even more effective treatments and will be able to harness the same targeted therapy for oral and topical treatments as well.

Some examples of biologic drugs to treat psoriasis include Humira, Enbrel, and Remicade.

Siegel says that some people believe that eliminating certain foods from their diet, such as gluten, dairy, sugar, or red meat can reduce inflammation and therefore lower their chances of a psoriatic flare.

Others believe that consuming certain vitamins, herbs and supplements, such as fish oil or turmeric, can do the same, he says. The truth is that there is not enough scientific evidence to substantiate these claims, and the medical community doesnt know for sure how diet impacts psoriatic disease.

What the medical community does agree on, however, is that people with psoriatic disease should maintain a healthy weight, and thats where diet and exercise can play and important role. Research has found that maintaining a healthy weight lowers the risk of developing co-morbidities or related health conditions like diabetes or cardiovascular disease.

Siegel says that another big myth about psoriasis is that there isnt a treatment available for patients to achieve clear or nearly clear skin.

This is simply not true, he says. There have been tremendous advancements and there are currently a number of safe, effective and affordable options. The first step people living with psoriasis should take is to work with their health care provider to discuss a treatment strategy. By following a goal-oriented, trackable treatment strategy, people living with psoriasis should expect to begin seeing results in three to six months.

Adds Beer: Psoriasis is now one of the most researched skin diseases and each year we get better and better treatments. See your dermatologist to get more information.

2017 NewsmaxHealth. All rights reserved.

Read the rest here:

Psoriasis: New Treatments Help Millions Manage Common Skin Condition – Newsmax

Dr. Reddy’s Out-Licenses Plaque Psoriasis Drug to Encore Dermatology – Pharmaceutical Processing

Dr. Reddy’s Laboratories announces the out-licensing of DFD-06 to Encore Dermatology.

Dr. Reddys Laboratories Ltd., through its wholly owned subsidiary Promius Pharma, LLC, announced today that it has out-licensed the future development, manufacturing, and commercialization rights of DFD-06, a topical high potency steroid, to Encore Dermatology Inc. The drug is intended to be used for treatment of moderate to severe plaque psoriasis.

Under the terms of the agreement, Encore will be responsible for the commercialization of DFD-06 in the United States. Promius Pharma is eligible to receive certain pre- and post- commercialization milestone payments of up to $32.5 million, followed by fixed royalty payments on net sales.

We believe Encore and its management team are well positioned to realize the full potential of this asset DFD-06. We look forward to obtaining NDA approval this fall, enabling Encores management team to quickly deliver this product to the providers and their patients, says Anil Namboodiripad, Ph.D., senior vice president, proprietary products, and president, Promius Pharma.

(Source: Business Wire)

Continued here:

Dr. Reddy’s Out-Licenses Plaque Psoriasis Drug to Encore Dermatology – Pharmaceutical Processing

Psoriasis symptoms and causes – RTN Newspaper

PSORIASIS is a common skin condition that causes skin cells to grow too quickly and build up, leaving thick, red, silvery, or scaly patches (plaques) on the surface of the skin. Psoriasis is not contagious so you cant get it from touching someone who has it. Its an accepted fact, but not proven, that men are more prone to suffering from psoriasis than women.

Symptoms

Skin patches with raised edges that are red with silvery-white scales (called plaques), rashes on genitals, scalp, or in skin folds (such as the folds you have on your knees and elbows), itching, pain, dry, cracked skin that may bleed, thickened, pitted, or discoloured nails, swollen, painful joints (psoriatic arthritis).

For most people, psoriasis patches vary in size. They can range from small spots with dandruff-like flakes to wide patches that cover large areas of skin. Mild psoriasis can be annoying, but severe cases can be disfiguring, painful, and sometimes disabling. Flares (when psoriasis gets worse) occur in cycles, with symptoms that last for weeks to months and may then lessen for some time before coming back.

Causes

Medical researchers believe that psoriasis is a chronic autoimmune skin disease; however, it has also been linked to genetic and environmental factors.

There are certain things that can trigger a psoriasis flare-up (when the psoriasis becomes worse). Such as: Certain infections (such as strep throat), certain medicines (for high blood pressure), stress, smoking, cold, dry weather, alcohol and injury to skin (insect bites/cuts/burns, etc.)

There isnt a cure for psoriasis, but there are many good ways to keep the symptoms under control with the most important being general cleanliness of the skin.

More here:

Psoriasis symptoms and causes – RTN Newspaper

Study Dismisses Concerns that Psoriasis Treatment Could Trigger IBD – IBD News Today

Taltz (ixekizumab), an approved antibody treatment for plaque psoriasis, targets a cytokine that is thought to play a role in the development of inflammatory bowel disease (IBD).That connection has caused concerns that administration of the drug might increase occurrence of IBDs in patients with psoriasis. So,Eli Lilly and Company, the maker of Taltz, conducted a study to determine if there was a significant correlation.

Results showed that rates of new IBD cases were observed in less than 1 percent of the psoriasis patients receiving Taltz. They reported that flares of pre-existing disease also were rare.

Titled Inflammatory bowel disease among patients with psoriasis treated with ixekizumab: A presentation of adjudicated data from an integrated database of 7 randomized controlled and uncontrolled trials, the study was published in the American Journal of Dermatology.

Taltz targets the cytokine interleulin-17 (IL-17). Previous studies have suggested a potential role of IL-17A in the pathogenesis (disease course) of IBD, although results have been inconclusive. According to a press releasepublished in theMedical News Bulletin, trials using antagonists of IL-17A have failed to prove effective against IBDs.

The Eli Lilly study study included data from 4,029 patients with moderate-to-severe psoriasis who had received Taltz. Participants previously were enrolled in one of the seven clinical trials for Taltz already underway.

The study did have some limitations, including the fact that the study did not collect any information on the patients family histories before trial initiation, and the fact that there was no information collected on the duration of earlier therapies that could have led to IBD symptoms, namely before exposure to Taltz.

Because the trial is not fully conclusive, the authors recommend that dermatologists monitor patients with concomitant psoriasis and IBD who are receiving IL-17 antibody therapy and advocate for disclosing all the potential risks that IL-17A antagonist treatment could entail.

Plaque psoriasis is an inflammatory skin condition that is characterized by the appearance of raised red scales, which are often itchy and painful. The condition has a significant genetic overlap with IBD and patients often develop certain IBDs, like ulcerative colitis (UC) or Crohns disease, as co-morbidities.

In February 2015, research found that the genetic susceptibility to Crohns and psoriasis persisted for hundreds of thousands of years, dating back to pre-Neanderthals.

Visit link:

Study Dismisses Concerns that Psoriasis Treatment Could Trigger IBD – IBD News Today

Arteric Develops Website Centerpiece of Award-Winning Psoriasis … – Benzinga

Summit, NJ, August 21, 2017 –(PR.com)– Arteric (http://arteric.com), a digital healthcare marketing agency that fuses exceptional software development skill with healthcare marketing expertise to help brands connect patients, caregivers, and healthcare professionals with the health information and tools that patients need to live longer, healthier lives proudly announces that the patient activation campaign Rise Up Against Psoriasis won a coveted Golden Scalpel award. In collaboration with McCann Health London and McCann Wien, Arteric developed and implemented the campaign’s website centerpiece (riseagainstpsoriasis.com/de) for Celgene sterreich (Celgene Austria). The strategic process behind this award-winning collaboration is described in detail at arteric.com.

Presented by Pharma Marketing Club Austria, the Golden Scalpel awards represent best-in-class pharmaceutical advertising in Austria. Two juries of industry experts – one with general marketing expertise and the other with digital marketing expertise – selected award recipients. Rise Up Against Psoriasis received a Golden Scalpel in the category Digital Media non-RX/non-OTC.

Psoriasis poses risks that go far beyond skin lesions. Research findings point to an increased risk of depression, anxiety, and risk of suicide in people with psoriasis. [1] The Rise Up Against Psoriasis campaign was developed to activate patients who had disengaged from the healthcare system.

The website accomplishes this through 4 tactics:

1. A short movie follows 3 people through their daily struggles to help psoriasis sufferers recognize that they are not alone. 2. A quiz helps psoriasis sufferers quantify the impact of the disease on their daily lives. 3. A physician finder connects psoriasis sufferers to local dermatologists. 4. A discussion guide creates the foundation for a successful conversation with the physician.

These tactics are delivered through a beautifully designed responsive website that is instrumented to track engagement and provide insights about visitors, to guide future campaign development.

Arteric’s president, Hans Kaspersetz, explains, “Rise Up Against Psoriasis has been successful because it authentically speaks to the psoriasis sufferer’s daily struggles with the disease – it calls out to all those directly and indirectly affected by psoriasis, sending the essential message that help is available. The website invites site visitors to complete the Dermatology Life Quality Index survey to assess the impact of psoriasis on their quality of life, helping to build context for a conversation with their doctor.”[2]

Mr. Kaspersetz continues, “Arteric has a robust global digital marketing practice with clients in North America, the EU, Asia, and Australia. For more than a decade, we’ve created websites and digital campaigns for audiences all over the world. Our team has delivered digital assets in 28 languages in 35 markets. We’re especially pleased to create locally recognized best-in-class work with international partners like McCann Health London.”

Jonathan Kukathasan, General Manager of McCann Health London, concurs. “While developing the Rise Up Against Psoriasis campaign, we worked alongside key partners to ensure it was a success. As the creative agency, we enjoyed working with Arteric, which played a critical role. It was great working alongside them to create this campaign and we look forward to working with them in the future.”

Mr. Kaspersetz summarizes the effort this way. “The award validates the years of effort we’ve invested in understanding global needs and local markets. Whether in the US or in Austria, our goal is to connect people with the health information and resources they need to live longer, healthier lives.”

For two decades, Arteric has worked directly with healthcare clients and partnered seamlessly with their service providers to develop award-winning websites, mobile apps, and Web applications that work everywhere and every time to help brands win. Contact Hans Kaspersetz at 201.558.9910 to put Arteric’s digital marketing expertise to work for your brand.

Learn more about Rise Up Against Psoriasis at http://www.riseagainstpsoriasis.com/de.

About Arteric Arteric is a digital healthcare marketing agency built on a foundation of technology expertise – digital strategy, software engineering, search engine optimization, and search engine marketing. Arteric develops the strategy and the software -websites, mobile apps, and Web applications – that drive pharmaceutical and biotechnology digital marketing campaigns and connect the public and healthcare professionals with information about life-changing therapies, technologies, and devices.

References 1. Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety and suicidality in patients with psoriasis: a population-based cohort study. Arch Dermatol. 2010;146(8):891-895. Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928071/. Accessed August 18, 2017. 2. Findlay A, Khan G. Dermatology Life Quality Index (DLQI). 1992. Available at http://www.bad.org.uk/shared/get-file.ashx?id=1653&itemtype=document. Accessed August 21, 2017.

Contact Information: Arteric Ross O’Shea 201.546.9910 Contact via Email http://arteric.com

Read the full story here: http://www.pr.com/press-release/727344

Press Release Distributed by PR.com

Originally posted here:

Arteric Develops Website Centerpiece of Award-Winning Psoriasis … – Benzinga

Psoriasis – What is Psoriasis? Basic Symptoms and Types

What Is Psoriasis?

Unpredictable and irritating, psoriasis is one of the most baffling and persistent of skin disorders. It’s characterized by skin cells that multiply up to 10 times faster than normal. As underlying cells reach the skin’s surface and die, their sheer volume causes raised, red plaques covered with white scales. Psoriasis typically occurs on the knees, elbows, and scalp, and it can also affect the torso, palms, and soles of the feet.

The symptoms of psoriasis vary depending on the type you have. Some common symptoms for plaque psoriasis — the most common variety of the condition — include:

Psoriasis can also be associated with psoriatic arthritis, which leads to pain and swelling in the joints. The National Psoriasis Foundation estimates that between 10% to 30% of people with psoriasis also have psoriatic arthritis.

Other forms of psoriasis include:

Pustular psoriasis , characterized by red and scaly skin on the palms of the hands and/or feet with tiny pustules

Guttate psoriasis, which often starts in childhood or young adulthood, is characterized by small, red spots, mainly on the torso and limbs. Triggers may be respiratory infections, strep throat, tonsillitis, stress, injury to the skin, and use of anti-malarial and beta-blocker medications.

Inverse psoriasis, characterized by bright red, shiny lesions that appear in skin folds, such as the armpits, groin area, and under the breasts

Erythrodermic psoriasis, characterized by periodic, fiery redness of the skin and shedding of scales in sheets; this form of psoriasis, triggered by withdrawal from a systemic psoriasis treatment, severe sunburn, infection, and certain medications, requires immediate medical treatment, because it can lead to severe illness.

People who suffer from psoriasis know that this uncomfortable and at times disfiguring skin disease can be difficult and frustrating to treat. The condition comes and goes in cycles of remissions and flare-ups over a lifetime. While there are medications and other therapies that can help to clear up the patches of red, scaly, thickened skin that are the hallmark of psoriasis, there is no cure.

A variety of factors — ranging from emotional stress and trauma to streptococcal infection — can cause an episode of psoriasis. Recent research indicates that some abnormality in the immune system is the key cause of psoriasis. As many as 80% of people having flare-ups report a recent emotional trauma, such as a new job or the death of a loved one. Most doctors believe such external stressors serve as triggers for an inherited defect in immune function.

Injured skin and certain drugs can aggravate psoriasis, including certain types of blood pressure medications (like beta-blockers), the anti-malarial medication hydroxychloroquine, and ibuprofen (Advil, Motrin, etc.).

Psoriasis tends to run in families, but it may be skip generations; a grandfather and his grandson may be affected, but the child’s mother never develops the disease. Although psoriasis may be stressful and embarrassing, most outbreaks are relatively harmless. With appropriate treatment, symptoms generally subside within a few months.

SOURCES: National Institute of Arthritis and Musculoskeletal and Skin Disease. National Psoriasis Foundation. The Psoriasis Foundation. American Academy of Dermatology.

Go here to read the rest:

Psoriasis – What is Psoriasis? Basic Symptoms and Types

Here Are The Signs That You May Have Psoriasis – Allure Magazine

If youve noticed inflamed, scaly skin on your body and wondered what it is (and what the hell you should do about it) we have good news and bad news. The bad news is that it sounds like you have psoriasis. The good news is that youre most likely not turning reptilian. OK, the actual good news is that there are tons of treatments available! This is really really good news because probably the worst thing you can do when you have psoriasis is to do nothing and hope it goes away on its own. Actually, thats not completely true; well get into what the absolute worst thing you can do for psoriasis is in a little bit.

Dr. Joshua Zeichner , MD, explains it in the simplest terms: Psoriasis is a condition in which the immune system gets angry at the skin, leading to red, scaly plaques. Usually youll see it on elbows and knees but psoriasis can appear anywhere, including the scalp, lower back, nails, and even the genitals.

You May Also Like

SkinCostco Is Now Selling One of Your Favorite Korean Beauty Products

Skin8 Rules of Layering Your Skin-Care Products

Want to get even more specific? This is a genetic, autoimmune, inflammatory condition in which your skin cells divide too quickly and do not shed quickly enough, says Dr. Tsippora Shainhouse MD, FAAD, a board-certified dermatologist in Beverly Hills and a clinical instructor at the University of Southern California. Thats what creates the inflamed, scaly plaques. According to Dr. Shainhouse, psoriasis is often associated with psoriatic arthritis, metabolic syndrome, elevated triglycerides, increased risk for heart disease, and obesity. Yikes. You can see why its not something you want to sleep on.

Getty Images

You can generally tell that its psoriasis thanks to the main symptom of the aforementioned scaly plaques that can be pink, white, or even silvery. Sometimes these plaques will itch, crack, and possibly even bleed. There are also different subtypes of psoriasis, according to Dr. Shainhouse: Inverse psoriasis appears in the underarms and groin; palmo-plantar psoriasis causes itchy or painful peeling and pustules on the palms and soles; and guttate psoriasis is named after ‘raindrops’, because you get a sudden eruption of small pink, scaly spots all over the trunk, usually after exposure to Strep throat, Dr. Shainhouse says. A dermatologist will have to examine your skin for a concrete diagnosis.

Getty Images

Once youve been diagnosed, you can discuss treatment plans with you dermatologist. Luckily, there are now quite a few different options available now for those suffering from psoriasis. According to Dr. Zeichner, your treatment will depend on how mild or severe your case is, as well as what kind of psoriasis you have. Mild cases of psoriasis may be treated with topicals anti-inflammatories including cortisones and Vitamin D creams, Dr. Zeichner says. More severe cases may require systemic medications like pills or shots to keep the inflammation calm. If you have scalp psoriasis, Dr. Zeichner suggests using over-the-counter tar shampoos, such as Neutrogena T-Gel , to relieve dandruff and itching.

Dr. Shainhouse seconds asking your doctor for topical or oral/injectable medications, depending on the severity of your psoriasis. You could also try an over-the-counter exfoliating product, but Dr. Shainhouse recommends getting advice from your dermatologist first. Exfoliating moisturizers can help to remove some of the thick scale, but this condition requires management by your dermatologist, she says.

Phototherapy could also be a viable option. UV light is generally a no-no in dermatology, since we know that too much can be associated with the development of skin cancer and melanoma, Dr. Shainhouse explains. However, it has an anti-inflammatory effect in psoriatic skin, and is a very useful option for reducing skin disease/symptoms.

Finally, Dr. Shainhouse also warns against doing certain things that could worsen your psoriasis. Picking at the scales is the last thing you should do. Rubbing and picking at the skin will actually worsen the spots, Dr. Shainhouse says. Psoriasis tends to develop in sites of skin trauma, including cuts and scratches. This is called the Koebner phenomenon. She also recommends maintaining a healthy body weight and avoiding drugs and alcohol, as obesity and substance abuse can also exacerbate psoriasis.

If you suspect you might have psoriasis, make an appointment with your dermatologist and check out the National Psoriasis Foundation at http://www.psoriasis.org .

In case that wasn’t quite comprehensive enough:

See the original post:

Here Are The Signs That You May Have Psoriasis – Allure Magazine

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

Most parents arent afraid to show their children affection in public. But Arizona mom Ashley Nagy says she makes a special point to kiss and cuddle her 19-month-old daughter Charlie when the two are out and about because Charlie suffers from psoriasis , a chronic autoimmune disease that speeds up the growth of skin cellsand Nagy says she wants to make sure people know it isnt contagious .

For the most part, Nagy tells SELF that strangers on the playground have been inquisitive, often simply asking, “What does she have? But some of the “ruder comments are Oh my goshyour daughter is sunburned . I cant believe you have her out in public or I dont want to see that, she says. She’s also noticed that other kids or mothers will stare at Charlie, and some parents will even keep their kids away from her daughter for fear of catching psoriasis. When that happens, I just pick her up and kiss her neck or cheeks, or rub her arm, Nagy says. Its my way of not confronting them, but showing that shes not contagious.

Nagy says that shes grateful that Charlie is so young that she doesnt realize whats happening. I just hope that Ive done a good [enough] job that when she starts to realize shes different, she has enough confidence to face people and not take what they say to heart, she says. Youre going to have random people who are mean and cruelyou cant control them, but you can control how you react to them.

About 7.5 million people in the U.S. have psoriasis, according to the American Academy of Dermatology . The condition is largely caused by genetics, but having genes associated with psoriasis doesnt mean youll actually develop the condition. In fact, at least 10 percent of people inherit one or more of the genes that can eventually lead to psoriasis, according to the National Psoriasis Foundation , but only 2 to 3 percent of people actually develop the disease.

That’s because, in order to actually develop the condition, you need to have a combination of the genes that cause it and to be exposed to particular triggers, such as stress, an injury to the skin (e.g. a sunburn), allergies , diet, an infection, certain medications (including lithium and the heart medication quinidine), and even the weather, the NPF says.

Although people of any age can have the condition, its primarily seen in adults. Charlies symptoms first began soon after she was born, Nagy says, and she was diagnosed with psoriasis when she was 4 months old. People were shocked at how young she was when she was diagnosed, Nagy says.

People who suffer from psoriasis may experience flare-ups in which they have the characteristic red, itchy, scaly skin patches, but in between flare-ups their skin may look normal. Charlie is now on an anti-inflammatory diet that also avoids gluten and dairy to help try to ward off flare-ups. That seems to help a lot, Nagy says. But Charlie still suffers from flare-ups, which cause her to develop red patches all over her body that itch. Shell point to her marks and say, Ouchies, ouchies, Nagy says. When Charlie has a flare-up, shes itchy and uncomfortable all day, and has trouble sleeping at night. But, when shes not suffering from a flare-up, her condition doesnt really impact her, Nagy says.

Psoriasis is caused by inflammation and not an infection, so it’s not contagious at all, Gary Goldenberg , M.D., assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai Hospital, tells SELF. Luckily, there are several treatments for psoriasis, and the best one for each patient depends on how severe their symptoms are. Mild psoriasis can be treated with creams and lotions, or over-the-counter medication like steroid creams, Dr. Goldenberg says.

Petrolatum-based moisturizers are often the most helpful because they form a protective seal over the skin to keep it hydrated while also minimizing the appearance of flakes on the skin, Joshua Zeichner , M.D., a New York City-based board-certified dermatologist, tells SELF. People can also develop psoriasis on their scalp, which can be treated with over-the-counter medicated shampoos, such as Neutrogena T/Gel shampoo , Dr. Zeichner says.

For people with more severe cases, there are biologic immune-modifying medications that alter the immune system reactions that lead to psoriasis, Cynthia Bailey, M.D., a diplomate of the American Board of Dermatology and president and CEO of Advanced Skin Care and Dermatology Inc. , tells SELF. That includes infliximab, for instance, which reduces the effects of substances in the body that can cause inflammation.

While it can be treated, it cannot be cured, Dr. Goldenberg says. Some patients can experience a remission of their disease that can last years, but this is unpredictable and rare. In most cases, patients need to keep treating their psoriasis for the rest of their lives to avoid flare-ups. We can help reduce signs of the disease on the skin, however the rash often reappears if you stop treating it, Dr. Zeichner says.

If psoriasis runs in your family, you can develop it at any point in your life, Dr. Bailey says, and its more likely to show up as you age. Although we don’t know exactly why, it “probably has something to do with the process of aging and how it impacts the immune system, Dr. Bailey says. If psoriasis runs in your family, she recommends limiting your alcohol intake, maintaining a healthy diet, and getting regular exercise to lower your odds of developing the condition.

Charlie used to have to see her doctor every two weeks to have her blood drawn for testing and monitoring purposes, Nagy says, but now she goes to the doctor every four months for her condition. Weve been keeping it at bay with her diet and bath regimen, she says. Nagy has started a GoFundMe to help pay for her daughters medical bills. A lot of people see ads on TV for psoriasis medications, but they dont actually know what psoriasis is, Nagy says. I want them to see what it looks like firsthandand to show that its not contagious.

Related:

You May Also Like: This Professional Ballerina With Vitiligo Will Change How You Think About Beauty

Go here to read the rest:

This Mom Always Kisses Her Daughter in Public to Show That Psoriasis Isn’t Contagious – SELF

Arteric Develops Website Centerpiece of Award-Winning Psoriasis Patient Activation Campaign – Benzinga

Summit, NJ, August 21, 2017 –(PR.com)– Arteric (http://arteric.com), a digital healthcare marketing agency that fuses exceptional software development skill with healthcare marketing expertise to help brands connect patients, caregivers, and healthcare professionals with the health information and tools that patients need to live longer, healthier lives proudly announces that the patient activation campaign Rise Up Against Psoriasis won a coveted Golden Scalpel award. In collaboration with McCann Health London and McCann Wien, Arteric developed and implemented the campaign’s website centerpiece (riseagainstpsoriasis.com/de) for Celgene sterreich (Celgene Austria). The strategic process behind this award-winning collaboration is described in detail at arteric.com.

Presented by Pharma Marketing Club Austria, the Golden Scalpel awards represent best-in-class pharmaceutical advertising in Austria. Two juries of industry experts – one with general marketing expertise and the other with digital marketing expertise – selected award recipients. Rise Up Against Psoriasis received a Golden Scalpel in the category Digital Media non-RX/non-OTC.

Psoriasis poses risks that go far beyond skin lesions. Research findings point to an increased risk of depression, anxiety, and risk of suicide in people with psoriasis. [1] The Rise Up Against Psoriasis campaign was developed to activate patients who had disengaged from the healthcare system.

The website accomplishes this through 4 tactics:

1. A short movie follows 3 people through their daily struggles to help psoriasis sufferers recognize that they are not alone. 2. A quiz helps psoriasis sufferers quantify the impact of the disease on their daily lives. 3. A physician finder connects psoriasis sufferers to local dermatologists. 4. A discussion guide creates the foundation for a successful conversation with the physician.

These tactics are delivered through a beautifully designed responsive website that is instrumented to track engagement and provide insights about visitors, to guide future campaign development.

Arteric’s president, Hans Kaspersetz, explains, “Rise Up Against Psoriasis has been successful because it authentically speaks to the psoriasis sufferer’s daily struggles with the disease – it calls out to all those directly and indirectly affected by psoriasis, sending the essential message that help is available. The website invites site visitors to complete the Dermatology Life Quality Index survey to assess the impact of psoriasis on their quality of life, helping to build context for a conversation with their doctor.”[2]

Mr. Kaspersetz continues, “Arteric has a robust global digital marketing practice with clients in North America, the EU, Asia, and Australia. For more than a decade, we’ve created websites and digital campaigns for audiences all over the world. Our team has delivered digital assets in 28 languages in 35 markets. We’re especially pleased to create locally recognized best-in-class work with international partners like McCann Health London.”

Jonathan Kukathasan, General Manager of McCann Health London, concurs. “While developing the Rise Up Against Psoriasis campaign, we worked alongside key partners to ensure it was a success. As the creative agency, we enjoyed working with Arteric, which played a critical role. It was great working alongside them to create this campaign and we look forward to working with them in the future.”

Mr. Kaspersetz summarizes the effort this way. “The award validates the years of effort we’ve invested in understanding global needs and local markets. Whether in the US or in Austria, our goal is to connect people with the health information and resources they need to live longer, healthier lives.”

For two decades, Arteric has worked directly with healthcare clients and partnered seamlessly with their service providers to develop award-winning websites, mobile apps, and Web applications that work everywhere and every time to help brands win. Contact Hans Kaspersetz at 201.558.9910 to put Arteric’s digital marketing expertise to work for your brand.

Learn more about Rise Up Against Psoriasis at http://www.riseagainstpsoriasis.com/de.

About Arteric Arteric is a digital healthcare marketing agency built on a foundation of technology expertise – digital strategy, software engineering, search engine optimization, and search engine marketing. Arteric develops the strategy and the software -websites, mobile apps, and Web applications – that drive pharmaceutical and biotechnology digital marketing campaigns and connect the public and healthcare professionals with information about life-changing therapies, technologies, and devices.

References 1. Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety and suicidality in patients with psoriasis: a population-based cohort study. Arch Dermatol. 2010;146(8):891-895. Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928071/. Accessed August 18, 2017. 2. Findlay A, Khan G. Dermatology Life Quality Index (DLQI). 1992. Available at http://www.bad.org.uk/shared/get-file.ashx?id=1653&itemtype=document. Accessed August 21, 2017.

Contact Information: Arteric Ross O’Shea 201.546.9910 Contact via Email http://arteric.com

Read the full story here: http://www.pr.com/press-release/727344

Press Release Distributed by PR.com

Read more:

Arteric Develops Website Centerpiece of Award-Winning Psoriasis Patient Activation Campaign – Benzinga

Study Dismisses Concerns that Psoriasis Treatment Could Trigger IBD – IBD News Today

Taltz (ixekizumab), an approved antibody treatment for plaque psoriasis, targets a cytokine that is thought to play a role in the development of inflammatory bowel disease (IBD).That connection has caused concerns that administration of the drug might increase occurrence of IBDs in patients with psoriasis. So,Eli Lilly and Company, the maker of Taltz, conducted a study to determine if there was a significant correlation.

Results showed that rates of new IBD cases were observed in less than 1 percent of the psoriasis patients receiving Taltz. They reported that flares of pre-existing disease also were rare.

Titled Inflammatory bowel disease among patients with psoriasis treated with ixekizumab: A presentation of adjudicated data from an integrated database of 7 randomized controlled and uncontrolled trials, the study was published in the American Journal of Dermatology.

Taltz targets the cytokine interleulin-17 (IL-17). Previous studies have suggested a potential role of IL-17A in the pathogenesis (disease course) of IBD, although results have been inconclusive. According to a press releasepublished in theMedical News Bulletin, trials using antagonists of IL-17A have failed to prove effective against IBDs.

The Eli Lilly study study included data from 4,029 patients with moderate-to-severe psoriasis who had received Taltz. Participants previously were enrolled in one of the seven clinical trials for Taltz already underway.

The study did have some limitations, including the fact that the study did not collect any information on the patients family histories before trial initiation, and the fact that there was no information collected on the duration of earlier therapies that could have led to IBD symptoms, namely before exposure to Taltz.

Because the trial is not fully conclusive, the authors recommend that dermatologists monitor patients with concomitant psoriasis and IBD who are receiving IL-17 antibody therapy and advocate for disclosing all the potential risks that IL-17A antagonist treatment could entail.

Plaque psoriasis is an inflammatory skin condition that is characterized by the appearance of raised red scales, which are often itchy and painful. The condition has a significant genetic overlap with IBD and patients often develop certain IBDs, like ulcerative colitis (UC) or Crohns disease, as co-morbidities.

In February 2015, research found that the genetic susceptibility to Crohns and psoriasis persisted for hundreds of thousands of years, dating back to pre-Neanderthals.

Link:

Study Dismisses Concerns that Psoriasis Treatment Could Trigger IBD – IBD News Today

Cardiovascular Events Rise With Increased Duration of Psoriasis – MedicalResearch.com (blog)

MedicalResearch.com Interview with:

Dr. Egeberg

Alexander Egeberg, MD PhD Gentofte Hospital Department of Dermatology and Allergy Kildegrdsvej 28 2900 Hellerup Denmark

MedicalResearch.com: What is the background for this study? What are the main findings? Response: The majority cardiovascular events in psoriasis occur in patients at low risk by traditional cardiovascular risk calculators. It has been speculated that long-term exposure to systemic inflammation may increase the risk of adverse cardiovascular outcomes. Therefore, clinically available historical features such as disease duration may identify those at higher risk for cardiovascular disease.

Using a translational epidemiological approach, combining 18F-fluorodeoxyglucose positron emission tomography computed tomography scanningwith nationwide epidemiological data of more than four million individuals, we provide the first convincing evidence to suggest a detrimental effect of psoriasis duration on cardiovascular disease beyond traditional cardiovascular risk factors, even in patients deemed low-risk by conventional risk scores. We found a 1% increase in future major adverse cardiovascular event risk per additional year of disease duration. This finding has an effect size similar to smoking, a well-established cardiovascular risk factor.

MedicalResearch.com: What should clinicians and patients take away from your report?

Response: Disease duration may represent a potentially easily obtainable measure of risk forcardiovascular disease in psoriasis and other inflammatory-based diseases.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: The burning question is whether, and to what extent, systemic treatment of psoriasis may affect (and reduce) the cardiovascular risk in psoriasis. While observational studies suggest a protective effect of TNF inhibitors, experimental data are less clear cut. This is an area of great interest now and in the coming years.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:

The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events Alexander Egeberg, Lone Skov, Aditya A. Joshi, Lotus Mallbris, Gunnar H. Gislason, Jashin J. Wu, Justin Rodante, Joseph B. Lerman, Mark A. Ahlman, Joel M. Gelfand, Nehal N. Mehta DOI: http://dx.doi.org/10.1016/j.jaad.2017.06.028 Publication stage: In Press Corrected Proof Published online: August 18, 2017

Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

. Bookmark the

.

Continued here:

Cardiovascular Events Rise With Increased Duration of Psoriasis – MedicalResearch.com (blog)


12345...102030...