Top Health-care stocks:

JNJ: -0.1%

PFE: -0.3%

ABT: flat

MRK: flat

AMGN: flat

Health-care shares were generally unchanged in pre-market trade Monday.

In health-care stocks news, Shares of Neothetics Inc. ( NEOT ) gained pre-market Monday after the company said it is commencing two pivotal Phase 3 trials to determine the efficacy, safety and tolerability of LIPO-202 for reducing central abdominal bulging. The specialty pharmaceutical firm said the two trials will be conducted in approximately 80 sites across the U.S and enroll a total of 1,600 patients.

Shares in the company were trading 1.2% higher at $8.25 during pre-market trading . Over the past 52 weeks, the company has traded between $6.11 and $14.10.

AEterna Zentaris ( AEZS ) said Monday it plans to conduct a phase 3 clinical study to demonstrate the efficacy of Macrilen (macimorelin), an orally-active ghrelin agonist for use in evaluating adult growth hormone deficiency ( AGHD ). The study will also evaluate the effects of Macrilen on myocardial repolarization.

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Health Care Sector Update for 04/13/2015: NEOT, AEZS, REPH