"House Republicans have made significant progress on budget decisions and these family discussions will continue amongst the conference," Ryan spokeswoman AshLee Strong said in a statement.

The Freedom Caucus and Tuesday Group each represents enough House Republicans to stymie legislation on its own.

Outside organizations including powerful business lobby groups are increasingly worried that the disagreement could lead to a political stand-off that prevents tax reform from occurring.

"No other reforms under consideration rise to the importance of pro-growth, comprehensive tax reform," the U.S. Chamber of Commerce, the Business Roundtable, the National Association of Manufacturers and the National Federation of Independent Business said in a joint letter to Republican and Democratic congressional leaders on Wednesday.

Republican moderates also worry that adding mandatory cuts to a reconciliation bill would create unpalatable legislation that reduces benefits for the poor while granting tax cuts to corporations and wealthy individuals, according to aides.

The House Budget Committee canceled plans to send a resolution for fiscal 2018 to the floor this week, after the chairmen of several other committees rejected efforts to wring $250 billion in mandatory spending from spending.

Freedom Caucus members want much larger cuts.

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Moderate House Republicans warn of trouble for tax reform - CNBC