Nanotechnology-enabled tissue engineering is a rapidly growing field. At the core of tissue engineering is the construction of scaffolds out of biomaterials to provide mechanical support and guide cell growth into new tissues or organs. In particular, electrospun biodegradable polymeric nanofibers are being used in scaffolds for engineering various tissues such as nerves, cartilages or bone. Electrospinning is a fabrication technique which can produce nanoscale fibers from more than 100 different polymers. The electrospun nanofibers are typically collected as nonwoven mats with random orientation. A new study has now demonstrated the fabrication of a novel class of nanofiber scaffold composed of radially-aligned, electrospun nanofibers and also demonstrated the unique application of these materials as effective biomedical patches/scaffolds that could prove to be beneficial during neurosurgery.