Biomechanical energy is one of the main energy components in biological systems. Developing an effective technique that can convert biomechanical energy into electricity is important for the future of in vivo implantable biosensors and other nanomedical devices. Researchers have already shown the conversion of biomechanical energy into electricity by a muscle-movement-driven nanogenerator to harvest mechanical energy from body movement under in vitro conditions. In a first demonstration of using nanotechnology to convert tiny physical motion into electricity in an in vivo environment, the same team has now reported the implanting of a nanogenerator in a live rat to harvest energy generated by its breath and heartbeat.