AAV-Mediated Inclusion Formation as a Novel Gene Therapy Strategy for ALS – Video




AAV-Mediated Inclusion Formation as a Novel Gene Therapy Strategy for ALS Ole Isacson, Ph.D., McLean Hospital. Dr. Isacson is a CDMRP-funded investigator supported by the DoD Amyotrophic Lateral Sclerosis Research Program (ALSRP) Continue reading

Imaging Nanoparticles and Validation of Specificity in In-Vivo Animal Models – Video




Imaging Nanoparticles and Validation of Specificity in In-Vivo Animal Models New nanoparticles and nanotechnology designed for medical applications require rigorous evaluation both in vitro and in vivo. The purpose of many of these nanoparticles is to improve the treatment of disease through improved specificity, delivery of novel therapeutics, improved delivery of existing therapeutics, or delivery of novel combinations of therapeutics. In other cases, the goal of the nanoparticle may be improved detection or stratification of a disease Continue reading

European regulators back first gene therapy drug

LONDON (Reuters) – European regulators have recommended approval of the Western world's first gene therapy drug — after rejecting it on three previous occasions — in a significant advance for the novel medical technology. More than 20 years since the first experiments with the ground-breaking method for fixing faulty genes, scientists and drug companies are still struggling to apply gene … Continue reading

Book Review: I Burn Paris

I Burn Paris, a novel by the Polish Futurist and communist Bruno Jasieski (1901-38), is a strange, fascinating and at times rambling adventure in which the reader is asked not so much to suspend her disbelief as to hang it from the nearest electrical wire and watch the sparks fly. Soren A. Gauger and Marcin Piekoszewski’s translation is the first time I Burn Paris has been brought into English and it thus fills a void for scholars and lovers of Polish literature and Futurism; this is a significant work from one of the movement’s most outspoken and tragic characters. Continue reading