A Signature for Success

Contact Information Available for logged-in reporters only Newswise November 19, 2014, New York, NY A team led by Ludwig and Memorial Sloan Kettering (MSK) researchers has published a landmark study on the genetic basis of response to a powerful cancer therapy known as immune checkpoint blockade. Their paper, in the current issue of the New England Journal of Medicine, describes the precise genetic signatures in melanoma tumors that determine whether a patient will respond to one such therapy. It also explains in exquisite detail how those genetic profiles translate into subtle molecular changes that enable the immune system attack of cancer cells in response to immune checkpoint blockade



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(1) A Signature for Success
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Bubble Baby: Gene Therapy Cured 2-year-old Girl Of Deadly SCID At UCLA

The gene therapy that has seemingly cured a 2-year-old girl could be used to treat other diseases, like Sickle Cell Anemia.



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(1) Bubble Baby: Gene Therapy Cured 2-year-old Girl Of Deadly SCID At UCLA
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In autoimmune diseases, researchers pinpoint genetic risks, cellular culprits

PUBLIC RELEASE DATE: 29-Oct-2014 Contact: Pete Farley peter.farley@ucsf.edu 415-502-6397 University of California – San Francisco @ucsf Scores of autoimmune diseases afflicting one in 12 Americans ranging from type 1 diabetes, to multiple sclerosis (MS), to rheumatoid arthritis, to asthma mysteriously cause the immune system to harm tissues within our own bodies. Now, a new study pinpoints the complex genetic origins for many of these diseases, a discovery that may lead to better diagnosis and ultimately to improved treatments.



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(1) In autoimmune diseases, researchers pinpoint genetic risks, cellular culprits
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Earthing: Natural Medicine to help you Lose Weight, Sleep Better and Have More Energy! – Video




Earthing: Natural Medicine to help you Lose Weight, Sleep Better and Have More Energy! http://tiny.cc/bye-fat Get rid of that fat forever http://tiny.cc/bye-fat Learn how to sleep better, improve your immune system and feel better overall. Get back in touch with the Earth! By: Zofitness

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(1) Earthing: Natural Medicine to help you Lose Weight, Sleep Better and Have More Energy! - Video
URL: http://www.youtube.com/watch?v=P6c_gIbdr7o


Children's genes affect their mothers' risk of rheumatoid arthritis

PUBLIC RELEASE DATE: 19-Oct-2014 Contact: Nalini Padmanabhan press@ashg.org 301-634-7346 American Society of Human Genetics @GeneticsSociety BETHESDA, MD A child’s genetic makeup may contribute to his or her mother’s risk of rheumatoid arthritis, possibly explaining why women are at higher risk of developing the disease than men. This research will be presented Tuesday, October 21, at the American Society of Human Genetics (ASHG) 2014 Annual Meeting in San Diego.



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(1) Children's genes affect their mothers' risk of rheumatoid arthritis
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Genetic Defect Links Rare Infections to Autoimmune Diseases

Contact Information Available for logged-in reporters only Newswise (NEW YORK – Oct.



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(1) Genetic Defect Links Rare Infections to Autoimmune Diseases
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Amgen psoriasis drug succeeds late-stage trial

Amgen Inc said its experimental drug to treat a type of skin disease compared favorably with AbbVie Inc's Humira, a commonly prescribed drug for the condition, in a late-stage trial. The drug, ABP 501, was being tested in patients with plaque psoriasis, a skin disease caused by dysfunction of the immune system that leads to painful, itchy red patches



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(1) Amgen psoriasis drug succeeds late-stage trial
URL: http://finance.yahoo.com/news/amgen-psoriasis-drug-succeeds-stage-141414598.html;_ylt=AwrBEiQ2lTZUPRAAdYv_wgt.


Gene Therapy Shows Potential for 'Bubble Boy' Disease

Amy Norton HealthDay Reporter Posted: Thursday, October 9, 2014, 5:00 AM (HealthDay News) — A new form of gene therapy may offer a safe and effective way to treat “bubble boy” disease — a severe immune deficiency that is fatal unless treated in infancy.



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(1) Gene Therapy Shows Potential for 'Bubble Boy' Disease
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Stem cells use 'first aid kits' to repair damage

PUBLIC RELEASE DATE: 18-Sep-2014 Contact: Louise Walsh louise.walsh@admin.cam.ac.uk 44-012-237-65443 University of Cambridge @Cambridge_Uni Stem cells hold great promise as a means of repairing cells in conditions such as multiple sclerosis, stroke or injuries of the spinal cord because they have the ability to develop into almost any cell type. Now, new research shows that stem cell therapy can also work through a mechanism other than cell replacement.



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(1) Stem cells use 'first aid kits' to repair damage
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Cancer and the immune system: A double-edged sword

PUBLIC RELEASE DATE: 15-Sep-2014 Contact: Scott LaFee slafee@ucsd.edu 619-543-6163 University of California – San Diego @UCSanDiego During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells.



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(1) Cancer and the immune system: A double-edged sword
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Spirituality and health topic of Healthy Minds seminar

Explore the unique relationship between spirituality and physical health at the next Healthy Minds, Healthy Bodies seminar at Samaritan Albany General Hospital. The seminar will take place on Wednesday, May 21, from 6 to 7:30 p.m



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(1) Spirituality and health topic of Healthy Minds seminar
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International Space Station Tests Effects of Space on Human Immune Cells

Scientists from the University of Zurich are currently studying immune cells on the International Space Station (ISS) to find out how deep space missions affect the human immune system.



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(1) International Space Station Tests Effects of Space on Human Immune Cells
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Replacing insulin through stem cell-derived pancreatic cells under the skin

PUBLIC RELEASE DATE: 24-Mar-2014 Contact: Susan Gammon Ph.D. sgammon@sanfordburnham.org 858-795-5012 Sanford-Burnham Medical Research Institute LA JOLLA, Calif., March 25, 2014 Sanford-Burnham Medical Research Institute (Sanford-Burnham) and UC San Diego School of Medicine scientists have shown that by encapsulating immature pancreatic cells derived from human embryonic stem cells (hESC), and implanting them under the skin in animal models of diabetes, sufficient insulin is produced to maintain glucose levels without unwanted potential trade-offs of the technology.



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(1) Replacing insulin through stem cell-derived pancreatic cells under the skin
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Stem cell combination therapy improves traumatic brain injury outcomes

Traumatic brain injuries (TBI), sustained by close to 2 million Americans annually, including military personnel, are debilitating and devastating for patients and their families. Regardless of severity, those with TBI can suffer a range of motor, behavioral, intellectual and cognitive disabilities over the short or long term.



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(1) Stem cell combination therapy improves traumatic brain injury outcomes
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USF study finds stem cell combination therapy improves traumatic brain injury outcomes

PUBLIC RELEASE DATE: 20-Mar-2014 Contact: Anne DeLotto Baier abaier@health.usf.edu 813-974-3303 University of South Florida (USF Innovation) Tampa, FL (Mar.



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(1) USF study finds stem cell combination therapy improves traumatic brain injury outcomes
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What you need to know about PSORIASIS

Q: One of the two people from Pangasinan who were reported by a radio-TV network to be afflicted with a flesh-eating disease was actually suffering from psoriasis according to the Department of Health. What is psoriasis



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(1) What you need to know about PSORIASIS
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2014: BBC World News – Gene Therapy Breakthrough for Patients on HIV Medication – 6/3/14 – Video




2014: BBC World News – Gene Therapy Breakthrough for Patients on HIV Medication – 6/3/14 For the first time gene therapy has been used to boost the immune system of people with HIV. Scientists in the US have modified the genes of HIV patients whi… By: The LAME Channel

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(1) 2014: BBC World News - Gene Therapy Breakthrough for Patients on HIV Medication - 6/3/14 - Video
URL: http://www.youtube.com/watch?v=fvqdRFxnWKQ


VIDEO: Gene therapy breakthrough on HIV

For the first time gene therapy has been used to boost the immune system of people with HIV.



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(1) VIDEO: Gene therapy breakthrough on HIV
URL: http://ri.search.yahoo.com/_ylt=AwrBEiGsZxpTty0AFyH_wgt./RV=2/RE=1394268204/RO=10/RU=http://www.bbc.co.uk/news/health-26473802/RK=0/RS=IHBWw7_ELd5Vb6aQVi9SKYacfRY-