Gene Therapy Developed for ALS Treatment: New Biotech Company Neuralgene Enters Evaluation Phase

BOGOTA, Colombia, April 12, 2013 /PRNewswire/ — Startup biotechnology company Neuralgene (http://neuralgene.com) has announced that it will begin animal studies in May to evaluate the efficacy of PRCN-829, its new gene therapy agent for the treatment of amyotrophic lateral sclerosis (ALS). PRCN-829 is the first gene therapy for sporadic ALS Continue reading

Positive gene therapy results in large mammals of Duchenne muscular dystrophy

Usually, results from a new study help scientists inch their way toward an answer whether they are battling a health problem or are on the verge of a technological breakthrough. Once in a while, those results give them a giant leap forward. In a preliminary study in a canine model of Duchenne muscular dystrophy (DMD), University of Missouri scientists showed exactly such a leap using gene therapy to treat muscular dystrophy. Continue reading

Experts take quantum leap in gene therapy to treat muscular dystrophy

Washington, January 16 (ANI): In a preliminary study in a canine model of Duchenne muscular dystrophy (DMD), researchers have shown a giant leap using gene therapy to treat muscular dystrophy. Continue reading

Computational medicine – hottest tool against diseases

Washington, Nov 2 (IANS) Computational medicine, which is based on computer models and cutting edge software, is emerging as the hottest tool against unyielding cancers, cardiovascular conditions and a host of other diseases, says a study. Continue reading

Brown University, UCI researchers create Drosophila fruit fly model of epilepsy

In a newly reported set of experiments that show the value of a particularly precise but difficult genetic engineering technique, researchers at Brown University and the University of California-Irvine have created a Drosophila fruit fly model of epilepsy to discern the mechanism by which temperature-dependent seizures happen. The researchers used a technique called homologous recombination – a more precise and sophisticated technique than transgenic gene engineering – to give flies a disease-causing mutation that is a direct analogue of the mutation that leads to febrile epileptic seizures in humans Continue reading

Gene therapy a possible option for obesity

Newly published obesity research coming out of the University of Alberta has touched upon a possible avenue for obesity reduction. Jason Dyck, a U of A medical researcher and professor, is the lead researcher for the study, which may be close to finding a new way to combat obesity. In this study, mice are fed a high-fat, high-sugar diet the type of diet that generally leads to obesity. Continue reading

'Bubble babies' immune systems restored

LOS ANGELES UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called “bubble boy” disease, a life-threatening condition that if left untreated can be fatal within one to two years. Continue reading

Stem cell researchers use gene therapy to restore immune systems in 'Bubble Boy' disease

ScienceDaily (Sep. 11, 2012) UCLA stem cell researchers have found that a gene therapy regimen can safely restore immune systems to children with so-called “Bubble Boy” disease, a life threatening condition that if left untreated can be fatal within one to two years Continue reading

Method to prevent rejection of disease-fighting proteins described in Human Gene Therapy journal

Public release date: 7-Aug-2012 [ | E-mail | Share ] Contact: Jennifer Quigley jquigley@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News New Rochelle, NY, August 7, 2012The body’s natural reaction to reject replacement proteins represents a major obstacle to the successful use of gene therapy to cure a range of life-threatening diseases. Continue reading

Gene Mutations Identified as Cause of Most Cases of Rare Disorder–AHC

Newswise (SALT LAKE CITY)Alternating hemiplegia of childhood (AHC) is a rare disorder that usually begins in infancy, with intermittent episodes of paralysis and stiffness, first affecting one side of the body, then the other. Symptoms mysteriously appear and disappear, again and again, and affected children often experience dozens of episodes per week. As they get older, children fall progressively behind their peers in both intellectual abilities and motor skills, and more than half develop epilepsy. Continue reading