Biochemistry | Chemistry

Despite previous setbacks, Rebecca Plimpton lands publication in major science journal.

Dr. Simmons steps down after 17 years as the director of the center. Dr. Steven L. Castle, also from the Department of Chemistry and Biochemistry, will be the center's new associate director.

Komal Kedia, who represented the College of Physical and Mathematica Sciences in BYU's 2014 3MT competition, was recently featured on BYU Radio for her work with Dr. Graves.

Scientists working in Professor Josh Andersen's cancer research lab have made significant discoveries which may lower the amount of chemotherapy needed to treat cancer.

Biochemistry is the chemistry of living systems, or the study of what living systems are composed of and how they function at the molecular level. As a discipline, Biochemistry lies at the nexus of Chemistry and Biology, and seeks to understand the physicochemical basis for the traits of life, including metabolism, heredity, and all aspects of physiology and pathophysiology. The science of Biochemistry broadly includes molecular biology, as well as bioorganic, bioinorganic, and biophysical chemistry; and it relates to all biomedical fields including immunology, neurobiology, cancer biology, pharmacology, and developmental biology.

For more information about research in the Andersen Lab and living in Provo, click here: The Andersen Lab, Living in Provo. The health of an organism is linked to the tightly regulated balance between cell proliferation and cell death. Any aberrant tilt in this balance can lead to some of the most devastating human diseases. For example, excessive proliferation unbalanced ...

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Additional research areas: HIV/AIDS, Immunology and Molecular Biology A major concern in the treatment of HIV-infected subjects is the establishment of "reservoirs" or sites where HIV escapes intervention by drugs or the immune system. These sanctuary sites store infectious virus that serves to perpetuate infection. The primary cellular reservoirs in humans consist of latently infected CD4 T lymphocytes, monocytes/macrophages, and ...

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Dr. Christensens lab works in the fields of biochemistry and bioanalytical chemistry. His lab develops methods that apply optical spectroscopy, time-lapse microscopy, and other current analytical and biophysical techniques to questions in biochemistry, biophysics, cell and microbiology. A current area of research in my lab grew out of our discovery several years ago that the anthrax toxin receptors capillary morphogenesis ...

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For more information about research in the Graves Lab, click here. Serum proteomics to identify biomarkers of human disease. Over the past few years, I (in conjunction with collaborators at the University of Utah Medical School) have explored quantitative differences in serum proteins, peptides, and lipids in pregnant women who went on to experience a preterm birth in their pregnancy ...

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My research explores mechanisms used by living cells to control the synthesis and degradation of protein. Specifically, we use mass spectrometry and stable isotopes to label newly synthesized molecules with a time dependent tag. This allows us to measure both in vivo concentrations, and replacement rate. With a mass spectrometer, the time-dependent stable isotope enrichment can be measured in any ...

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My laboratory's research focuses on signal transduction in the cancer cell. In particular, we are interested in a group of genes we have cloned that are activated during cell division. Our research determined that one of these genes encodes a previously undescribed cyclooxygenase, a critical enzyme involved in the synthesis of prostaglandins and thromboxane. These fatty-acid derived molecules are hormone-like ...

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BIOINORGANIC CHEMISTRY Biological systems require trace amounts of metal ions to sustain life. Metal ions are required at the active sites of many enzymes and are essential to catalyze some of the most energetically demanding reactions in biology. Unfortunately, these highly reactive metal ions also catalyze deleterious reactions for biological systems if the metal ion is permitted to be free ...

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Mechanisms of Assembly of Signaling Complexes Most cellular functions are performed by proteins associated together into complexes. In fact, many proteins cannot even exist in the cell without their binding partners. These protein complexes often require the help of other proteins, called chaperones, to bring the complexes together. This is certainly the case for protein complexes involved in cell signaling ...

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Biochemistry | Chemistry

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