Last Updated Oct 29, 2014 3:34 AM EDT

WALLOPS ISLAND, Va. -- An Orbital Sciences Corp. Antares rocket making only its fifth flight exploded seconds after launch from the Virginia coast Tuesday, erupting in a spectacular fireball and destroying an uncrewed Cygnus cargo ship in a disheartening failure for NASA's commercial space station resupply program.

The mishap occurred about 15 seconds after liftoff from the Mid-Atlantic Regional Spaceport at NASA's Wallops Island Flight Facility as the 139-foot-tall two-stage rocket climbed away on the power of its two Russian-built first-stage engines.

"We have ignition... and we have liftoff of the Antares Orb 3 mission to bring Cygnus on its third (resupply) mission to the ISS," said NASA's launch commentator as the Antares lifted off. "Main engines at 108 percent, attitude nominal."

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CBS space consultant William Harwood reacts as he watches the explosion just after liftoff in Virginia of an unmanned cargo rocket carrying supp...

At roughly that moment, the exhaust plume suddenly intensified, followed an instant later by a detonation of some sort at the base of the rocket. The booster, engulfed in flames, then slowly fell back to Earth, exploding in a titanic conflagration as its remaining liquid oxygen and refined kerosene propellants ignited in a huge fireball.

At impact, flaming debris shot away into the night sky like a fireworks display, some of it presumably from solid propellant used in the rocket's second stage. Scattered fires erupted around the launch pad and a towering cloud of smoke climbed into the night sky.

While property damage appeared extensive, Orbital officials said there were no injuries.

It was not clear watching video replays of the launching what might have gone wrong, whether it involved one or both Aerojet Rocketdyne AJ26 first stage engines or some other system.

Link:

NASA: No danger to space station after supply rocket blows up