The Mount Sinai Health System and RenalytixAI have announced a multi-center study designed to examine kidney-related complications and long-term outcomes linked to COVID-19. The study will be conducted in multiple centers in the United States and will utilize the artificial-intelligence enabled in vitro diagnostic platform, KidneyIntelX, to assess the risk of progression of kidney disease as well as the risk of kidney failure in patients surviving COVID-19.
The MASKED-COVID (Multi-Center Assessment of Survivors for Kidney Disease after COVID-19) study was announced in a press release from RenalytixAI, the developers of KidneyIntelX, and will expand on the study announced in April that focuses on the impact of COVID-19 in the acute hospitalized setting. The teams expected to participate in the study include the Mount Sinai Health System Icahn School of Medicine at Mount Sinai, Yale New Haven Health/Yale School of Medicine, Michigan Medicine/University of Michigan Medical School, Johns Hopkins Medicine/The Johns Hopkins University Medical School, and Rutgers, The State University of New Jersey/Rutgers New Jersey Medical School.
The risk for new chronic kidney disease (CKD) in the short-term or longer-term progression of kidney disease in patients who have recovered from COVID-19 will be assessed via KidneyIntelX. The system will generate a unique patient risk score using diverse data points, including validated blood and urine-based biomarkers, inherited genetics, and other patient data from electronic health records, that will be incorporated into the KidneyIntelX machine learning-enabled algorithm. Mount Sinai Health Systems serologic SARS-CoV-2 testing will be used to assess a patients antibody levels to COVID-19 over time, providing insights into the interaction between immune response and kidney-related complications in this patient population.
F. Perry Wilson, MD, MSCE, Yale University School of Medicine and MASKED-COVID principal investigator, said, With the pandemic spread of COVID-19 and the increased morbidity and mortality from COVID-19 in patients with diabetes, CKD, and acute kidney injury, it is imperative to define the underlying mechanisms of COVID-associated kidney disease and develop solutions to guide patient care. This can be best achieved through collaboration in all aspects including data sharing, biomarker analysis, data analytics, and clinical translation. RenalytixAI and Mount Sinai have assembled an outstanding team to address critical issues regarding COVID-19 and kidney disease.
Evren Azeloglu, PhD, at the Icahn School of Medicine at Mount Sinai, said, There are so many questions yet to be answered regarding COVID-19 and kidney disease. For example, we dont yet know the risk factor and mediators of AKI to CKD transition after COVID-19. We also dont know the predictors of long-term outcomes after COVID-19. Moreover, we need to understand how this second hit from COVID-19 interacts with other risk factors such as underlying APOL1 genotypes to heighten the potential for proteinuric nephropathy.
The MASKED-COVID study will be coordinated by Mount Sinai. Initial research findings are expected to be reported in late 2020, with the goal of launching KidneyIntelX commercialization activities in this COVID-109 population targeted for H1 2012. For more information, visit http://www.mountsinai.org.
Visit link:
MASKED-COVID Study to Assess Renal-Related Complications of COVID-19 - DocWire News
- "Shift Happens" - November 8th, 2009 [November 8th, 2009]
- Getting Started With Your Personal Statement - November 8th, 2009 [November 8th, 2009]
- I started this blog 1 year ago. I'm ready to become a medical doctor. - November 8th, 2009 [November 8th, 2009]
- Poll Results: "What is your GPA?" - November 8th, 2009 [November 8th, 2009]
- Why Ross University School of Medicine? - November 8th, 2009 [November 8th, 2009]
- Why Ross University? (Continued) - November 8th, 2009 [November 8th, 2009]
- Filling out applications with the last 4 years in mind. - November 8th, 2009 [November 8th, 2009]
- "Active and Passive Euthanasia" - November 8th, 2009 [November 8th, 2009]
- 300 Word Personal Statement - First Draft - November 8th, 2009 [November 8th, 2009]
- 300 Word Personal Statement - 2nd Draft - November 8th, 2009 [November 8th, 2009]
- "Where did you do EMT training at?" - November 8th, 2009 [November 8th, 2009]
- "is this jonathan that went to brazil in the summer of 2006?" - November 8th, 2009 [November 8th, 2009]
- First Application is Away - Ross University - November 8th, 2009 [November 8th, 2009]
- AMCAS—The American Medical College Application Service - November 8th, 2009 [November 8th, 2009]
- The Student Doctor Network - November 8th, 2009 [November 8th, 2009]
- Crime Incident - Public Safety Announcement: STUDENTS - November 8th, 2009 [November 8th, 2009]
- AMCAS Deadlines & Delays - Answered - November 8th, 2009 [November 8th, 2009]
- Headstart on Secondary Applications - The Student Doctor Network - November 8th, 2009 [November 8th, 2009]
- The Complete Medical School & Admissions Guide - Revisited - November 8th, 2009 [November 8th, 2009]
- Interview Status - Ross University - November 8th, 2009 [November 8th, 2009]
- Finished my first interview. - November 8th, 2009 [November 8th, 2009]
- "You have a 95% chance of acceptance..." - November 8th, 2009 [November 8th, 2009]
- "I was just wondering if I have to go to medical school i will have to start college allover again." - November 8th, 2009 [November 8th, 2009]
- Interview Feedback - Allopathic Medical Schools - Ross University School of Medicine (Dominica Caribbean) - November 8th, 2009 [November 8th, 2009]
- ACCEPTED! - November 8th, 2009 [November 8th, 2009]
- Step 1 Revisited - November 8th, 2009 [November 8th, 2009]
- A Few More Thoughts On Moving - November 8th, 2009 [November 8th, 2009]
- Update - November 8th, 2009 [November 8th, 2009]
- Closing In - November 8th, 2009 [November 8th, 2009]
- Internet/Computer Hell - November 8th, 2009 [November 8th, 2009]
- Back On The Net - November 8th, 2009 [November 8th, 2009]
- 1 More Day - November 8th, 2009 [November 8th, 2009]
- Loan Deferment Blog - November 8th, 2009 [November 8th, 2009]
- Graduated! - November 8th, 2009 [November 8th, 2009]
- What Happened? - November 8th, 2009 [November 8th, 2009]
- Interesting Case - November 8th, 2009 [November 8th, 2009]
- What Made Me Stupid? - November 8th, 2009 [November 8th, 2009]
- Blah. - November 8th, 2009 [November 8th, 2009]
- Call - November 8th, 2009 [November 8th, 2009]
- Medicine in the Media - November 8th, 2009 [November 8th, 2009]
- Was Medical School Worth It? - November 8th, 2009 [November 8th, 2009]
- Off I Go... - November 8th, 2009 [November 8th, 2009]
- Is It Worth It, Part 2 - November 8th, 2009 [November 8th, 2009]
- Oriented - November 8th, 2009 [November 8th, 2009]
- GLBT in Medical School - November 8th, 2009 [November 8th, 2009]
- GLBT in Residency Applications - November 8th, 2009 [November 8th, 2009]
- I Survived - November 8th, 2009 [November 8th, 2009]
- Reflections on the First Week - November 8th, 2009 [November 8th, 2009]
- All Good Things Must End - November 8th, 2009 [November 8th, 2009]
- The Lone Coyote is Back - November 8th, 2009 [November 8th, 2009]
- Pre-med student switches gears to teach in Chicago school - Chicago Tribune - March 8th, 2010 [March 8th, 2010]
- Old-school barbecue coming to spot near Fort Worth medical district - Fort Worth Star Telegram - March 8th, 2010 [March 8th, 2010]
- Nursing home drug use puts many at risk - Boston Globe - March 8th, 2010 [March 8th, 2010]
- Dr. Anita Figueredo, first female surgeon in San Diego, dies at 93 - Los Angeles Times - March 8th, 2010 [March 8th, 2010]
- Stimulus funds pay for monkey research in NC - MiamiHerald.com - March 8th, 2010 [March 8th, 2010]
- Medicine as an economic engine - Buffalo News - March 8th, 2010 [March 8th, 2010]
- UM medical school feels the squeeze - MiamiHerald.com - March 8th, 2010 [March 8th, 2010]
- HARVARD MEDICAL SCHOOL ADVISER Bell's palsy not as serious as it appears - Detroit Free Press - March 8th, 2010 [March 8th, 2010]
- Baylor medical school works to get back on track - Houston Chronicle - March 8th, 2010 [March 8th, 2010]
- From community college to Amherst College and Yale Medical School - WalletPop (blog) - March 8th, 2010 [March 8th, 2010]
- Man questions merit of coke monkey study - UPI.com - March 8th, 2010 [March 8th, 2010]
- School Board has questions it wants answered about onsite medical clinic - Terre Haute Tribune Star - March 9th, 2010 [March 9th, 2010]
- Stimulus Funds Pay for Monkey Research - NewsMax.com - March 9th, 2010 [March 9th, 2010]
- Babylon schools head: Teen's collapse unrelated to athletics - Newsday (subscription) - March 9th, 2010 [March 9th, 2010]
- Cost Of Medical School Rises In Recession - NPR - March 9th, 2010 [March 9th, 2010]
- Flu Shots in Children Help People of All Ages - New York Times - March 9th, 2010 [March 9th, 2010]
- A prescription for improving science education - Scope (blog) - March 9th, 2010 [March 9th, 2010]
- Live kidney donors do not die sooner: study - Reuters - March 9th, 2010 [March 9th, 2010]
- UW football player suspended after alleged assault - Seattle Post Intelligencer - March 10th, 2010 [March 10th, 2010]
- More Comparative Studies Needed to Guide Physicians Study finds less than a ... - ModernMedicine - March 10th, 2010 [March 10th, 2010]
- Conservationists worry about Mo. med school plan - KOAM-TV - March 10th, 2010 [March 10th, 2010]
- Dr. William D. Lynn - Baltimore Sun - March 10th, 2010 [March 10th, 2010]
- Suspect in North Dallas shootings became reclusive after parents died, family says - Dallas Morning News - March 10th, 2010 [March 10th, 2010]
- Drinkers Gain Less Weight - Harvard Crimson - March 10th, 2010 [March 10th, 2010]
- Long-Term Health Risks Low for Kidney Donors - WebMD - March 10th, 2010 [March 10th, 2010]
- School resource officer remains in critical condition - Middletown Journal - March 10th, 2010 [March 10th, 2010]
- New Lucian Leape Institute Report Finds That U.S. Medical Schools Are Falling ... - PR Newswire (press release) - March 10th, 2010 [March 10th, 2010]
- Dual degrees program expands for Mayo Medical School students - Post-Bulletin - March 10th, 2010 [March 10th, 2010]
- Comparative Effectiveness Research is a Must - TopNews United States - March 10th, 2010 [March 10th, 2010]
- Long Beach OKs medical pot ordinance - Contra Costa Times - March 10th, 2010 [March 10th, 2010]