When it comes to distribution of energy via cables, Electrical failures like tripping of switchgears/motors/panels in general arises due to cable failures/cable faults/cuts on cable etc. At my work place 80% of the cable is laid in under ground cable trenches/buries cable trenches. Also being a coas
Monthly Archives: July 2010
Powersystem Related Simulator
Does anybody know powersystem related simulator? What are all the open source simulators are there in website?
Tonight! Morbid Anatomy in Conversation with Stephen Asma, Author of "On Monsters: An Unnatural History of Our Worst Fears," Bryant Park Reading Room
Tonight at Bryant Park Reading Room! Stephen Asma and I talk monsters, within and without, as investigated in his recent book On Monsters: An Unnatural History of Our Worst Fears. Full details follow; Hope to see you there!!
Word for Word Université at Bryant Park
In cooperation with Oxford University Press
Presents
Stephen Asma, author of On Monsters: An Unnatural History of Our Worst Fears
In conversation with
Joanna Ebenstein, Morbid Anatomy Blog and Library
“Real or imagined, literal or metaphorical, monsters have exerted a dread fascination on the human mind for many centuries. Using philosophical treatises, theological tracts, newspapers, films, and novels, author Stephen T. Asma unpacks traditional monster stories for the clues they offer about the inner logic of our fears and fascinations throughout the ages.” – Amazon.com review
Please join us for a fascinating discussion of the monsters in our lives and our need to classify them. Stephen Asma is the distinguished scholar and Professor of Philosophy at Columbia College Chicago. Joanna Ebenstein is the creator and writer of the Morbid Anatomy blog and the related Brooklyn-based Morbid Anatomy Library.
Place: Bryant Park Reading Room*
Date: July 21, 2010
Time: 7pm
This program is free to the public. For more details, visit http://www.bryantpark.org.
*The Bryant Park Reading Room is located on the 42nd Street side of Bryant Park, between 5th Avenue and Sixth Avenue. Look for the big burgundy/white umbrellas.
Directions to Bryant Park: Subways B, D, F, V to 6th Ave. @ 42nd St. 7 line to 5th Ave.@ 42nd St.; Bus M1, M2, M3, M4, Q32, to 5th Ave.@ 42nd St.; M5, M6, M7 to 6th Ave.@ 42nd St.
More information about the event and the venue can be found here. You can find more about Stephen Asma's books here and here and more about he and his work here.
Image: As used in Asma's book, and as seen in the Anatomical Theatre exhibition: Museum of Anatomical Waxes “Luigi Cattezneo” (Museo Delle Cere Anatomiche “Luigi Cattaneo”): Bologna, Italy "Iniope–conjoined twins" Wax anatomical model; Cesare Bettini, Early 19th Century
Insulation Thickness
One circular pipe having operating temp.529c and surface temp. 450c pipe outer dia is 660mm. What is thickness of insulation?
Radio Control Transmitter & Receivers
Hi friends,
I want info about radio control transmitter & receiver. I have search on goggle lot but not got satisfactory information. Please anybody help me! I'm trying to make an RC toy.
Design of Rubber Band Powered Air Plane
Hi friends,
I am making a rubber band powered small air plane. I'm not getting proper rubber band. Also I want bearing for it.
Anybody can help me?
Pen Drive Data Corrupt
My 16GB Kingsten pen drive contents 4GB of data. But due to mis handling by other person with other PC, the major data suddenly disappeared.
The data is not deleted. But is not visible.
How can I recover my data? Please Help.
Losing Our Way to the "Final Frontier"
Well its been 41 years since the Apollo 11 landed on the Moon. These days we can only just get into near earth orbit with any sort of regularity. So I'm going to pose the question.
Why (or How) did we lose our way to the "Final Frontier"?
As a child of the 60's filled with the promise
Who’s the Greatest? It’s a Poll!
Who do you think is the greatest astronaut of all time? The good folks at Sky at Night Magazine have launched a poll to find out. The poll is in the August issue which by the way is on sale now.
Graham Southorn, Editor of the magazine made the comment: “We are setting out to honour those brave explorers who have journeyed beyond Earth, with a poll to find the greatest astronaut. We had to make some tough choices, but in the end we’ve narrowed the selection down to 15 people. Now we need your help to select the greatest of all time.”
Notably absent from the “short list” is John Glenn which kind of surprised me, not that I’d necessarily vote for him, but I’m not sure I’d have excluded him especially after looking at the list.
Still, it’s quite a group:
1) Anousheh Ansari
2) Buzz Aldrin
3) Neil Armstrong
4) Frank Borman
5) Michael Foale
6) Yuri Gagarin
7) Sergei Krikalev
Jim Lovell
9) Alexei Leonov
10) Bruce McCandless
11) Valeri Polyakov
12) Story Musgrave
13) Harrison Schmidt
14) Alan Shepard
15) John Young
Go on over to Sky at Night Magazine to read about the choices and cast your vote!!
Surface Tracking
How does the surface tracking occur in insulation?
Calorie Restriction, Mitochondria, and Hormesis
A recent paper points to mitochondrially induced hormesis as a root cause of increased longevity with reduced calorie intake - which meshes well with the role of autophagy in this process. It confirms the importance of mitochondria in longevity, and once again shows that a little ongoing damage is actually a good thing: "Calorie restriction (CR) is the only proven regimen which confers lifespan extension benefits across the various phyla right from unicellular organisms like yeast to primates. In a bid to elucidate the mechanism of calorie-restriction-mediated life span extension, the role of mitochondria in the process was investigated. In this study, we found that the mitochondrial content in CR cells remains unaltered as compared to cells grown on nonrestricted media. However, mitochondria isolated from CR cells showed increased respiration and elevated reactive oxygen species levels without augmenting adenosine triphosphate (ATP) generation. The antioxidant defense system was amplified in CR mitochondria, and in CR cells a cross protection to hydrogen-peroxide-induced stress was also observed. Moreover, we also documented that a functional electron transport chain was vital for the life span extension benefits of calorie restriction. Altogether, our results indicate that calorie restriction elicits mitohormetic effect, which ultimately leads to longevity benefit."
View the Article Under Discussion: http://www.ncbi.nlm.nih.gov/pubmed/20640543
Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/
Nanoparticles and Stem Cells Versus Atherosclerosis
Via PhysOrg.com: "A technique that combines nanotechnology with adult stem cells appears to destroy atherosclerotic plaque and rejuvenate the arteries ... nanoparticles (microscopic particles with at least one dimension less than 80 nm) were infused into the heart of pigs along with adult stem cells. After the nanoparticles were heated by laser light, they burned away arterial plaque. However, nanoparticles were less effective at eliminating plaque if not combined with adult stem cells. ... Unlike angioplasty, a common treatment for atherosclerosis, this new technique seems to actually demolish the plaque. ... The researchers found that plaque volume shrunk considerably in the nanoparticle groups immediately after the procedure (an average of 28.9 percent across the three groups) and six months later plaque volume had declined 56.8 percent on average. ... both groups that received stem cells showed signs of new blood vessel growth (neovascularization) and restoration of artery function."
View the Article Under Discussion: http://www.physorg.com/news198775684.html
Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/
Start metformin early when diabetes type II is first diagnosed
Initiating metformin soon after diabetes diagnosis and while A1C is low might preserve ?-cell function, prolong the effectiveness of metformin, reduce lifetime glycemic burden, and prevent diabetes complications.
These findings support the current treatment algorithm for hyperglycemia management that recommends metformin initiation when diabetes is first diagnosed.
Video: How the Body Works - The Pancreas.
References:
Secondary Failure of Metformin Monotherapy in Clinical Practice. Diabetes Care March 2010 vol. 33 no. 3 501-506.
Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.
Slices
This lasercut and etched model of the brain is made up of 32 laser etched sections that were layered together to give the illusion of a whole brain. Created by Dwight Song, this piece was inspired by MRI images and was originally made as part of his thesis project in graduate architecture.
Now it’s for sale on Etsy for $160! There were only 2 versions made.
Tonight at Observatory! "Morbid Ink: Field Notes on the Human Memorial Tattoo" with Dr. John Troyer
Morbid Anatomy presents at Observatory Tonight (!!!), July 20th. Hope to see you there!
Morbid Ink: Field Notes on the Human Memorial Tattoo
An Illustrated lecture with Dr. John Troyer, Deputy Director, Centre for Death and Society, University of Bath
Date: Tuesday July 20th
Time: 8:00
Admission: $5
Presented by Morbid AnatomyIn 1891, Samuel F. O’Reilly of New York, NY patented the first “…electromotor tattooing-machine,” a modern and innovative device that permanently inserted ink into the human skin. O’Reilly’s invention revolutionized tattooing and forever altered the underlying concept behind a human tattoo, i.e., the writing of history on the body. Tattooing of the body most certainly predates the O’Reilly machine (by several centuries) but one kind of human experience remains constant in this history: the memorial tattoo.
Memorial tattooing is, as Marita Sturken discusses the memorialization of the dead, a technology of memory. Yet the tattoo is more than just a representation of the dead. It is a historiographical practice in which the living person seeks to make death intelligible by permanently altering his or her own body. In this way, memorial tattooing not only establishes a new language of intelligibility between the living and the dead, it produces a historical text carried on the historian’s body. A memorial tattoo is an image but it is also (and most importantly) a narrative.
Human tattoos have been described over the centuries as speaking scars and/or the true writing of savages; cut from the body and then collected by Victorian era gentlemen. These intricately inked pieces of skin have been pressed between glass and then hidden away in museum collections, waiting to be re-discovered by the morbidly curious. The history of tattooing is the story of Homo sapiens’ self-invention and unavoidable ends.
Tattoo artists have a popular saying within their profession: Love lasts forever but a tattoo lasts six months longer.
And so too, I will add, does death
Dr. John Troyer is the Death and Dying Practices Associate and RCUK Fellow at the Centre for Death and Society at the University of Bath. He received his doctorate from the University of Minnesota in Comparative Studies in Discourse and Society in May 2006. From 2007-2008 he was a Visiting Assistant Professor in the Department of Comparative Studies at The Ohio State University teaching the cultural studies of science and technology. Within the field of Death Studies, he analyzes the global history of science and technology and its effects on the dead body. He is a co-founder of the Death Reference Desk website and his first book, Technologies of the Human Corpse, will appear in spring 2011.
You can find out more about this presentation here. You can get directions to Observatory--which is next door to the Morbid Anatomy Library (more on that here)--by clicking here. You can find out more about Observatory here, join our mailing list by clicking here, and join us on Facebook by clicking here.
Prevalence of unsuspected uterine cavity abnormalities diagnosed by office hysteroscopy prior to in vitro fertilization
BACKGROUND
Whether implantation occurs after in vitro fertilization (IVF) depends on the embryo, uterine receptivity or a combination of both. The prevalence of minor intrauterine abnormalities identified at hysteroscopy in cases with a normal transvaginal sonography (TVS) has been recorded to be as high as 20–40%. Diagnosing and treating such pathology prior to initiating IVF/intra-cytoplasmic sperm injection (ICSI), has been widely advocated without high-quality evidence of a beneficial effect. The objective of the current study was to assess, by screening office hysteroscopy, the prevalence of unsuspected intrauterine abnormalities in an asymptomatic population of IVF patients, in whom TVS had not revealed any pathology.
METHODS
The prevalence of unsuspected intrauterine abnormalities in patients allocated for a randomized controlled trial was prospectively assessed at two tertiary infertility care units: Academic Hospital at the Dutch-speaking Brussels Free University and University Medical Center Utrecht. A total of 678 unselected, asymptomatic, infertile women with a regular indication for a first IVF/ICSI treatment underwent office hysteroscopy. Only asymptomatic patients, aged ≤42 years, with a normal TVS and no previous hysteroscopy were included. The presence of predefined intrauterine abnormalities was recorded and described in a standardized manner.
RESULTS
Endometrial polyps were identified in 41 (6%) women and submucous myomas in 6 women (1%). Some women were also diagnosed with intrauterine adhesions (2%) or septa (2%). The overall prevalence of any predefined intrauterine abnormality in this IVF/ICSI population was 11%.
CONCLUSIONS
The observed prevalence of unsuspected intrauterine abnormalities in asymptomatic patients indicated for their first IVF/ICSI treatment appeared to be clearly lower than previously reported (11 versus 20–45%). This may have implications for the significance of these abnormalities regarding prospects in IVF/ICSI treatment cycles.
Ultra-conservative fertility-sparing strategy for bilateral borderline ovarian tumours: an 11-year follow-up
BACKGROUND
This is a prospective long-term extension study of a randomized controlled trial aimed to assess the risk–benefit ratio of an ultra-conservative fertility-sparing approach in patients with bilateral borderline ovarian tumours (BOTs).
METHODS
The experimental group (n = 15) was treated with an ultra-conservative surgical approach consisting of bilateral cystectomy, whereas the control group (n = 17) received a less conservative surgery consisting of oophorectomy plus controlateral cystectomy alone. All patients received a complete laparoscopic staging followed by a fertility enhancement programme. Patients who completed childbearing were treated with a non-conservative standard treatment at the first recurrence.
RESULTS
After a follow-up period of 128 (9 interquartile range (IQR); 115–150 range) and 132 (7 IQR; 117–152 range) months for the experimental and control groups, respectively (P = 0.25), the time to first baby-in-arm (P < 0.02) and the relative rate (RR) of baby-in-arm (8.05 [95% confidence interval (CI), 1.20–9.66; P < 0.01]) were significantly lower and higher, respectively, for the experimental compared with the control group. Although the time to first recurrence was significently (P < 0.01) shorter for the experimental group, in the regression analysis the difference did not reach the statistic significance (P = 0.14), and the RR of recurrence (1.23 [95% CI, 0.62–3.17; P = 0.41]) was not significant. Finally the number needed to treat for pregnancy was three, the number needed to harm for radical surgery was only two.
CONCLUSIONS
The ultra-conservative fertility-sparing approach is more effective than the standard approach in terms of reproductive outcomes, but presents a higher oncological risk.
Fertility after autologous ovine uterine-tubal-ovarian transplantation by vascular anastomosis to the external iliac vessels
BACKGROUND
Transplantation of the uterus has been suggested as a treatment of uterine factor infertility. This study investigates whether the sheep uterus can resume its capacity to harbour normal pregnancies after autotransplantation by vascular anastomosis.
METHODS
From 14 ewes, the uterus, excluding one uterine horn, was isolated along with its oviduct and ovary and preserved ex vivo and then transplanted back with end-to-side anastomosis of the vessels of the graft to the external iliac vessels. After recovery, the ewes underwent surgical examination and serum progesterone measurements to ascertain healing and ovarian activity. Afterwards, five autotransplanted and five control ewes were placed with a ram for mating. Caesarean sections were performed before the estimated term of pregnancy and data on fetal measures were compared.
RESULTS
Of the 14 ewes, seven survived surgery with ovarian activity intact and grafts showing normal appearance. Mating occurred in four of five transplanted ewes and in five out of five controls, and three transplanted animals and five control animals conceived. In one transplanted ewe, torsion of the uterus was observed after spontaneous initiation of labour. Foeti from transplanted mothers were comparable in size to those of controls.
CONCLUSIONS
Despite the encountered complications, this is the first report to demonstrate fertility and pregnancies going to term after autotransplantation of the uterus in an animal of a comparable size to the human.
Uterus transplantation in the baboon: methodology and long-term function after auto-transplantation
BACKGROUND
Techniques for uterus transplantation (UTx) have been developed in rodent/domestic animals towards future clinical introduction of UTx to treat uterine factor infertility. The aim of this study was to extend the UTx research into a non-human primate species by developing surgical techniques for uterus retrieval and transplantation in the baboon.
METHODS
Female baboons (n = 15) underwent surgery, with the initial five animals used for studies of pelvic vascular anatomy. Retrieval surgery included isolation of the ovarian veins and the uterine arteries together with the anterior branches of the internal iliacs. The utero-tubal-ovarian specimen was removed, flushed and kept ex vivo for 2 h when the two arterial ends and two venous ends were anastomosed side-to-side to construct one arterial and one venous end. These were, at auto-transplantation, anastomosed end-to-side to the external iliacs and the animals (n = 10) were evaluated concerning cyclicity and later by laparoscopy/laparotomy.
RESULTS
The total duration of organ retrieval, backtable preparation and transplantation was around 6 h with an overall ischaemic time of the specimen of about 3 h. One animal died due to cardiomyopathy. Five out of the nine surviving animals resumed cyclicity, as a sign of re-established ovarian function. Only two out of these five animals exhibited resumed menstruation, indicating re-established ovarian and uterine function. Laparoscopy confirmed normal-sized uteri in these two animals.
CONCLUSIONS
This study demonstrates the feasibility of UTx by vascular anastomosis in a non-human primate species. The low success rate demonstrates the complexity involved in UTx surgery and the need for further methodological developments.
Prestimulation parameters predicting live birth in anovulatory WHO Group II patients undergoing ovulation induction with gonadotrophins
BACKGROUND
The objective of this study was to identify baseline predictors of live birth in anovulatory patients undergoing ovulation induction, and based on these predictors, develop nomograms for estimation of the probability of live birth in a single cycle.
METHODS
Univariate and multivariate logistic regression were used for retrospective analysis of clinical, sonographic and endocrinological parameters collected prior to the start of ovarian stimulation in a cohort of anovulatory World Health Organization (WHO) Group II patients (n = 335), who were resistant to clomiphene citrate (CC) and therefore stimulated with gonadotrophins using a low-dose step-up protocol.
RESULTS
The univariate analysis identified age [OR = 0.91 (95% CI: 0.84–0.98), P = 0.015], duration of infertility [OR = 0.71 (95% CI: 0.56–0.91), P = 0.007], serum follicle stimulating hormone (FSH) concentration at the start of stimulation [OR = 0.83 (95% CI: 0.69–0.99), P = 0.034] and menstrual cycle pattern (P = 0.022) as significant predictors of live birth. Baseline concentrations of luteinizing hormone, androgens, glucose and insulin, as well as body mass index, were not predictors of live birth. In the multivariate analysis, duration of infertility, FSH and menstrual cycle pattern were independent predictors, and nomograms were designed with these three parameters for individual prediction of the probability of live birth.
CONCLUSIONS
The chances of live birth in women with WHO Group II anovulatory infertility resistant to CC undergoing ovulation induction with gonadotrophins is highly influenced by the menstrual cycle pattern. Increases in duration of infertility and concentration of FSH (within the normal range) before the start of stimulation have negative influences on the likelihood of achieving a live birth.