History of supercomputing – Wikipedia

The history of supercomputing goes back to the early 1920s in the United States with the IBM tabulators at Columbia University and a series of computers at Control Data Corporation (CDC), designed by Seymour Cray to use innovative designs and parallelism to achieve superior computational peak performance.[1] The CDC 6600, released in 1964, is generally considered the first supercomputer.[2][3] However, some earlier computers were considered supercomputers for their day, such as the 1954 IBM NORC[4], the 1960 UNIVAC LARC[5], and the IBM 7030 Stretch[6] and the Atlas, both in 1962.

While the supercomputers of the 1980s used only a few processors, in the 1990s, machines with thousands of processors began to appear both in the United States and in Japan, setting new computational performance records.

By the end of the 20th century, massively parallel supercomputers with thousands of "off-the-shelf" processors similar to those found in personal computers were constructed and broke through the teraflop computational barrier.

Progress in the first decade of the 21st century was dramatic and supercomputers with over 60,000 processors appeared, reaching petaflop performance levels.

The term "Super Computing" was first used in the New York World in 1929 to refer to large custom-built tabulators that IBM had made for Columbia University.

In 1957, a group of engineers left Sperry Corporation to form Control Data Corporation (CDC) in Minneapolis, Minnesota. Seymour Cray left Sperry a year later to join his colleagues at CDC.[1] In 1960, Cray completed the CDC 1604, one of the first solid-state computers, and the fastest computer in the world[dubious discuss] at a time when vacuum tubes were found in most large computers.[7]

Around 1960, Cray decided to design a computer that would be the fastest in the world by a large margin. After four years of experimentation along with Jim Thornton, and Dean Roush and about 30 other engineers Cray completed the CDC 6600 in 1964. Cray switched from germanium to silicon transistors, built by Fairchild Semiconductor, that used the planar process. These did not have the drawbacks of the mesa silicon transistors. He ran them very fast, and the speed of light restriction forced a very compact design with severe overheating problems, which were solved by introducing refrigeration, designed by Dean Roush.[8] Given that the 6600 outran all computers of the time by about 10 times, it was dubbed a supercomputer and defined the supercomputing market when one hundred computers were sold at $8 million each.[7][9]

The 6600 gained speed by "farming out" work to peripheral computing elements, freeing the CPU (Central Processing Unit) to process actual data. The Minnesota FORTRAN compiler for the machine was developed by Liddiard and Mundstock at the University of Minnesota and with it the 6600 could sustain 500kiloflops on standard mathematical operations.[10] In 1968, Cray completed the CDC 7600, again the fastest computer in the world.[7] At 36MHz, the 7600 had about three and a half times the clock speed of the 6600, but ran significantly faster due to other technical innovations. They sold only about 50 of the 7600s, not quite a failure. Cray left CDC in 1972 to form his own company.[7] Two years after his departure CDC delivered the STAR-100 which at 100megaflops was three times the speed of the 7600. Along with the Texas Instruments ASC, the STAR-100 was one of the first machines to use vector processing - the idea having been inspired around 1964 by the APL programming language.[11][12]

In 1956, a team at Manchester University in the United Kingdom, began development of MUSE a name derived from microsecond engine with the aim of eventually building a computer that could operate at processing speeds approaching onemicrosecond per instruction, about onemillion instructions per second.[13] Mu (or ) is a prefix in the SI and other systems of units denoting a factor of 106 (one millionth).

At the end of 1958, Ferranti agreed to begin to collaborate with Manchester University on the project, and the computer was shortly afterwards renamed Atlas, with the joint venture under the control of Tom Kilburn. The first Atlas was officially commissioned on 7December 1962, nearly three years before the Cray CDC 6600 supercomputer was introduced, as one of the world's first supercomputers - and was considered to be the most powerful computer in England and for a very short time was considered to be one of the most powerful computers in the world, and equivalent to four IBM 7094s.[14] It was said that whenever England's Atlas went offline half of the United Kingdom's computer capacity was lost.[14] The Atlas pioneered the use of virtual memory and paging as a way to extend the Atlas's working memory by combining its 16,384 words of primary core memory with an additional 96K words of secondary drum memory.[15] Atlas also pioneered the Atlas Supervisor, "considered by many to be the first recognizable modern operating system".[14]

Four years after leaving CDC, Cray delivered the 80MHz Cray-1 in 1976, and it became the most successful supercomputer in history.[12][16] The Cray-1 used integrated circuits with two gates per chip and was a vector processor which introduced a number of innovations such as chaining in which scalar and vector registers generate interim results which can be used immediately, without additional memory references which reduce computational speed.[8][17] The Cray X-MP (designed by Steve Chen) was released in 1982 as a 105MHz shared-memory parallel vector processor with better chaining support and multiple memory pipelines. All three floating point pipelines on the X-MP could operate simultaneously.[17]

The Cray-2 released in 1985 was a 4processor liquid cooled computer totally immersed in a tank of Fluorinert, which bubbled as it operated.[8] It could perform to 1.9gigaflops and was the world's second fastest supercomputer after M-13 (2.4gigaflops)[18] until 1990 when ETA-10G from CDC overtook both. The Cray 2 was a totally new design and did not use chaining and had a high memory latency, but used much pipelining and was ideal for problems that required large amounts of memory.[17] The software costs in developing a supercomputer should not be underestimated, as evidenced by the fact that in the 1980s the cost for software development at Cray came to equal what was spent on hardware.[19] That trend was partly responsible for a move away from the in-house, Cray Operating System to UNICOS based on Unix.[19]

The Cray Y-MP, also designed by Steve Chen, was released in 1988 as an improvement of the X-MP and could have eight vector processors at 167MHz with a peak performance of 333megaflops per processor.[17] In the late 1980s, Cray's experiment on the use of gallium arsenide semiconductors in the Cray-3 did not succeed. Seymour Roger Cray began to work on a massively parallel computer in the early 1990s, but died in a car accident in 1996 before it could be completed. Cray Research did, however, produce such computers.[16][8]

The Cray-2 which set the frontiers of supercomputing in the mid to late 1980s had only 8 processors. In the 1990s, supercomputers with thousands of processors began to appear. Another development at the end of the 1980s was the arrival of Japanese supercomputers, some of which were modeled after the Cray-1.

The SX-3/44R was announced by NEC Corporation in 1989 and a year later earned the fastest in the world title with a 4 processor model.[20] However, Fujitsu's Numerical Wind Tunnel supercomputer used 166 vector processors to gain the top spot in 1994. It had a peak speed of 1.7gigaflops per processor.[21][22] The Hitachi SR2201 on the other hand obtained a peak performance of 600gigaflops in 1996 by using 2048processors connected via a fast three-dimensional crossbar network.[23][24][25]

In the same timeframe the Intel Paragon could have 1000 to 4000 Intel i860 processors in various configurations, and was ranked the fastest in the world in 1993. The Paragon was a MIMD machine which connected processors via a high speed two-dimensional mesh, allowing processes to execute on separate nodes; communicating via the Message Passing Interface.[26] By 1995 Cray was also shipping massively parallel systems, e.g. the Cray T3E with over 2,000 processors, using a three-dimensional torus interconnect.[27][28]

The Paragon architecture soon led to the Intel ASCI Red supercomputer in the United States, which held the top supercomputing spot to the end of the 20th century as part of the Advanced Simulation and Computing Initiative. This was also a mesh-based MIMD massively-parallel system with over 9,000 compute nodes and well over 12 terabytes of disk storage, but used off-the-shelf Pentium Pro processors that could be found in everyday personal computers. ASCI Red was the first system ever to break through the 1teraflop barrier on the MP-Linpack benchmark in 1996; eventually reaching 2teraflops.[29]

Significant progress was made in the first decade of the 21st century. The efficiency of supercomputers continued to increase, but not dramatically so. The Cray C90 used 500 kilowatts of power in 1991, while by 2003 the ASCI Q used 3,000kW while being 2,000 times faster, increasing the performance per watt 300 fold.[30]

In 2004, the Earth Simulator supercomputer built by NEC at the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) reached 35.9teraflops, using 640nodes, each with eight proprietary vector processors.[31]

The IBM Blue Gene supercomputer architecture found widespread use in the early part of the 21st century, and 27 of the computers on the TOP500 list used that architecture. The Blue Gene approach is somewhat different in that it trades processor speed for low power consumption so that a larger number of processors can be used at air cooled temperatures. It can use over 60,000 processors, with 2048 processors "per rack", and connects them via a three-dimensional torus interconnect.[32][33]

Progress in China has been rapid, in that China placed 51st on the TOP500 list in June 2003, then 14th in November 2003, and 10th in June 2004 and then 5th during 2005, before gaining the top spot in 2010 with the 2.5petaflop Tianhe-I supercomputer.[34][35]

In July 2011, the 8.1petaflop Japanese K computer became the fastest in the world using over 60,000 SPARC64 VIIIfx processors housed in over 600 cabinets. The fact that K computer is over 60 times faster than the Earth Simulator, and that the Earth Simulator ranks as the 68th system in the world seven years after holding the top spot demonstrates both the rapid increase in top performance and the widespread growth of supercomputing technology worldwide.[36][37][38] By 2014, the Earth Simulator had dropped off the list and by 2018 K computer had dropped out of the top 10.

This is a list of the computers which appeared at the top of the Top500 list since 1993.[39] The "Peak speed" is given as the "Rmax" rating.

Combined performance of 500 largest supercomputers

Fastest supercomputer

Supercomputer in 500th place

The CoCom and its later replacement, the Wassenaar Arrangement, legally regulated - required licensing and approval and record-keeping; or banned entirely - the export of high-performance computers (HPCs) to certain countries. Such controls have become harder to justify, leading to loosening of these regulations. Some have argued these regulations were never justified.[40][41][42][43][44][45]

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History of supercomputing - Wikipedia

ORNL Launches Summit Supercomputer | ORNL

OAK RIDGE, Tenn., June 8, 2018The U.S. Department of Energys Oak Ridge National Laboratory today unveiled Summit as the worlds most powerful and smartest scientific supercomputer.

With a peak performance of 200,000 trillion calculations per secondor 200 petaflops, Summit will be eight times more powerful than ORNLs previous top-ranked system, Titan. For certain scientific applications, Summit will also be capable of more than three billion billion mixed precision calculations per second, or 3.3 exaops. Summit will provide unprecedented computing power for research in energy, advanced materials and artificial intelligence (AI), among other domains, enabling scientific discoveries that were previously impractical or impossible.

Todays launch of the Summit supercomputer demonstrates the strength of American leadership in scientific innovation and technology development. Its going to have a profound impact in energy research, scientific discovery, economic competitiveness and national security, said Secretary of Energy Rick Perry. I am truly excited by the potential of Summit, as it moves the nation one step closer to the goal of delivering an exascale supercomputing system by 2021. Summit will empower scientists to address a wide range of new challenges, accelerate discovery, spur innovation and above all, benefit the American people.

The IBM AC922 system consists of 4,608 compute servers, each containing two 22-core IBM Power9 processors and six NVIDIA Tesla V100 graphics processing unit accelerators, interconnected with dual-rail Mellanox EDR 100Gb/s InfiniBand. Summit also possesses more than 10 petabytes of memory paired with fast, high-bandwidth pathways for efficient data movement. The combination of cutting-edge hardware and robust data subsystems marks an evolution of the hybrid CPUGPU architecture successfully pioneered by the 27-petaflops Titan in 2012.

ORNL researchers have figured out how to harness the power and intelligence of Summits state-of-art architecture to successfully run the worlds first exascale scientific calculation. A team of scientists led by ORNLs Dan Jacobson and Wayne Joubert has leveraged the intelligence of the machine to run a 1.88 exaops comparative genomics calculation relevant to research in bioenergy and human health. The mixed precision exaops calculation produced identical results to more time-consuming 64-bit calculations previously run on Titan.

From its genesis 75 years ago, ORNL has a history and culture of solving large and difficult problems with national scope and impact, ORNL Director Thomas Zacharia said. ORNL scientists were among the scientific teams that achieved the first gigaflops calculations in 1988, the first teraflops calculations in 1998, the first petaflops calculations in 2008 and now the first exaops calculations in 2018. The pioneering research of ORNL scientists and engineers has played a pivotal role in our nations history and continues to shape our future. We look forward to welcoming the scientific user community to Summit as we pursue another 75 years of leadership in science.

In addition to scientific modeling and simulation, Summit offers unparalleled opportunities for the integration of AI and scientific discovery, enabling researchers to apply techniques like machine learning and deep learning to problems in human health, high-energy physics, materials discovery and other areas. Summit allows DOE and ORNL to respond to the White House Artificial Intelligence for America initiative.

Summit takes accelerated computing to the next level, with more computing power, more memory, an enormous high-performance file system and fast data paths to tie it all together. That means researchers will be able to get more accurate results faster, said Jeff Nichols, ORNL associate laboratory director for computing and computational sciences. Summits AI-optimized hardware also gives researchers an incredible platform for analyzing massive datasets and creating intelligent software to accelerate the pace of discovery.

Summit moves the nation one step closer to the goal of developing and delivering a fully capable exascale computing ecosystem for broad scientific use by 2021.

Summit will be open to select projects this year while ORNL and IBM work through the acceptance process for the machine. In 2019, the bulk of access to the IBM system will go to research teams selected through DOEs Innovative and Novel Computational Impact on Theory and Experiment, or INCITE, program.

In anticipation of Summits launch, researchers have been preparing applications for its next-generation architecture, with many ready to make effective use of the system on day one. Among the early science projects slated to run on Summit:

Astrophysics

Exploding stars, known as supernovas, supply researchers with clues related to how heavy elementsincluding the gold in jewelry and iron in bloodseeded the universe.

The highly scalable FLASH code models this process at multiple scalesfrom the nuclear level to the large-scale hydrodynamics of a stars final moments. On Summit, FLASH will go much further than previously possible, simulating supernova scenarios several thousand times longer and tracking about 12 times more elements than past projects.

Its at least a hundred times more computation than weve been able to do on earlier machines, said ORNL computational astrophysicist Bronson Messer. The sheer size of Summit will allow us to make very high-resolution models.

Materials

Developing the next generation of materials, including compounds for energy storage, conversion and production, depends on subatomic understanding of material behavior. QMCPACK, a quantum Monte Carlo application, simulates these interactions using first-principles calculations.

Up to now, researchers have only been able to simulate tens of atoms because of QMCPACKs high computational cost. Summit, however, can support materials composed of hundreds of atoms, a jump that aids the search for a more practical superconductora material that can transmit electricity with no energy loss.

Summits large, on-node memory is very important for increasing the range of complexity in materials and physical phenomena, said ORNL staff scientist Paul Kent. Additionally, the much more powerful nodes are really going to help us extend the range of our simulations.

Cancer Surveillance

One of the keys to combating cancer is developing tools that can automatically extract, analyze and sort existing health data to reveal previously hidden relationships between disease factors such as genes, biological markers and environment. Paired with unstructured data such as text-based reports and medical images, machine learning algorithms scaled on Summit will help supply medical researchers with a comprehensive view of the U.S. cancer population at a level of detail typically obtained only for clinical trial patients.

This cancer surveillance project is part of the CANcer Distributed Learning Environment, or CANDLE, a joint initiative between DOE and the National Cancer Institute.

Essentially, we are training computers to read documents and abstract information using large volumes of data, ORNL researcher Gina Tourassi said. Summit enables us to explore much more complex models in a time efficient way so we can identify the ones that are most effective.

Systems Biology

Applying machine learning and AI to genetic and biomedical datasets offers the potential to accelerate understanding of human health and disease outcomes.

Using a mix of AI techniques on Summit, researchers will be able to identify patterns in the function, cooperation and evolution of human proteins and cellular systems. These patterns can collectively give rise to clinical phenotypes, observable traits of diseases such as Alzheimers, heart disease or addiction, and inform the drug discovery process.

Through a strategic partnership project between ORNL and the U.S. Department of Veterans Affairs, researchers are combining clinical and genomic data with machine learning and Summits advanced architecture to understand the genetic factors that contribute to conditions such as opioid addiction.

The complexity of humans as a biological system is incredible, said ORNL computational biologist Dan Jacobson. Summit is enabling a whole new range of science that was simply not possible before it arrived.

Summit is part of the Oak Ridge Leadership Computing Facility, a DOE Office of Science User Facility located at ORNL. UT-Battelle manages ORNL for the Department of Energys Office of Science, the single largest supporter of basic research in the physical sciences in the United States. DOEs Office of Science is working to address some of the most pressing challenges of our time. For more information, please visithttp://science.energy.gov.

Image:https://www.ornl.gov/sites/default/files/2018-P01537.jpg

Caption: Oak Ridge National Laboratory launches Summit supercomputer.

Photos, b-roll and additional resources are available at http://olcf.ornl.gov/summit.

Access Summit Flickr Photos at https://flic.kr/s/aHsmmTwKLg.

Videos of Summit available at https://www.dropbox.com/sh/fy76ppz7cvjblia/AAC0m93xBWk4poM-rRwJbiZza?dl=0.

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ORNL Launches Summit Supercomputer | ORNL

Mesothelioma Symptoms: Asbestos Cancer Warning Signs

Mesothelioma Symptoms and Signs

Mesothelioma tumors begin as tiny nodules on the lining of the lungs or abdomen. The cancer doesnt cause symptoms until the tumors have grown and spread. This is usually around cancer stage 3 and 4, when tumors begin to press against the chest wall or abdominal cavity.

Recognizing symptoms of malignant mesothelioma early in the cancers development is nearly impossible because the disease doesnt produce early symptoms to identify.

Most early mesothelioma diagnoses happen by accident through routine X-rays or blood tests. By the time someone identifies warning signs, the cancer often has spread, making it difficult for doctors to treat.

Informing your primary care doctor about any history of asbestos exposure and seeking cancer screenings can help lead to an earlier-than-normal mesothelioma diagnosis and a much better chance of qualifying for life-extending therapy.

In the early stages of mesothelioma, you may notice:

Free information, books, wristbands and more for patients and caregivers.

The exact stage of the cancer at the time of diagnosis how far it has progressed is impossible to predict through symptoms alone. Most patients are not diagnosed until stage 3 or 4 because symptoms dont develop until later stages. The earlier the cancer is caught, the better the prognosis.

Addressing symptoms as soon as they develop can improve medical outcomes. When symptoms are identified and treated quickly, patients often benefit from higher quality of life and may live longer if the symptoms and cancer are controlled sooner.

Doctors can provide chemotherapy drugs that shrink peritoneal mesothelioma tumors and slow the growth and spread of cancer. It can be given before, during or after surgery. In some cases, doctors offer chemotherapy as the only treatment option. Chemotherapy drugs considered effective in treatment include pemetrexed, cisplatin, carboplatin and gemcitabine.

Doctors are now seeing extraordinary results with HIPEC. Once an experimental treatment, HIPEC starts with surgery to remove all visible tumors from the patients peritoneum. Next, doctors introduce a heated salt-water solution that contains chemotherapy drugs.

A machine pumps the medicine throughout the patients abdomen. This helps destroy any cancer cells left behind after surgery. Nearly half of peritoneal mesothelioma cancer patients who receive HIPEC can live at least five years after diagnosis.

This form of asbestos-related cancer develops in the lining around the heart. It is one of the rarest types of the disease. Symptoms include difficulty breathing and chest pains. They stem from thickening of the pericardium, the lining around the heart.

A lump in the testes is the most common sign of testicular mesothelioma the rarest of all types. It accounts for less than 1 percent of all mesothelioma cases.

Our patient advocates can answer your questions on mesothelioma and asbestos exposure.

Symptoms of mesothelioma and other asbestos cancers first emerge in small, subtle ways. This happens after the cancer has spread, which is around stage 3 or stage 4. Some are so minor that people and their doctors mistake them as symptoms of some other disorder or shrug them off entirely.

Mesothelioma starts to develop around 20 to 50 years after exposure to asbestos. This latency period is not related to the delayed onset of mesothelioma symptoms, but these concepts get easily confused because both involve an unexpected delay.

Symptoms usually dont make a noticeable impact on someones life until the cancer has reached a late stage. Most people who get mesothelioma of any type are diagnosed in stage 3 or stage 4. These are considered late or end stages.

I had gotten to the point where I couldnt walk without being out of breath. It scared the heck out of me. But having my lung drained was immediate relief. I felt so much better.

Although the decades-long latency period is similar with each type of the cancer, some studies suggest it is shorter for people with peritoneal mesothelioma. A 2011 study found women have a slightly longer latency period than men.

Nonspecialists often mistake pleural mesothelioma for less serious conditions. These include pneumonia, bronchial infection and COPD. People with peritoneal mesothelioma may initially be diagnosed with ovarian cancer or irritable bowel syndrome. Pericardial mesothelioma is so rare that doctors can easily confuse it with heart failure, coronary heart disease and other common heart illnesses.

I feel lucky, but I dont feel like a miracle. Ill reserve miracles for bigger and better things than me. Im just a grateful guy today who thinks every day I wake up is a gift.

A mesothelioma misdiagnosis can delay proper treatment. Anyone with a history of asbestos exposure should inform their primary care physician of their exposure. Also ask about annual cancer screenings. If you develop any abdominal or pulmonary issues in your lifetime, make sure to mention your asbestos exposure history to the medical professionals who provide your care.

The primary factor that affects the onset of mesothelioma symptoms is tumor growth and spreading.

Mesothelioma symptoms are caused by tumors that press against nerves, organs, bones and other parts of the body.

Small tumor size is the main reason why mesothelioma patients dont experience symptoms in the early stages of the cancers growth. Mesothelioma tumors typically dont become big enough to press against body parts until stage 3 or stage 4.

Our Patient Advocates can help you avoid a mesothelioma misdiagnosis by connecting you with a top doctor in your area.

Symptoms such as nerve pain that shoots down an arm may indicate cancer invasion has occurred locally in the chest. Mesothelioma tends to spread locally throughout the chest or abdominal cavity more often than spreading to distant locations throughout the body.

If you have a history of asbestos exposure and believe you have symptoms of mesothelioma, seek immediate medical attention. Tell your doctor about your exposure and alert them to the possibility of an asbestos-related disease. You will likely need to get a second opinion from a mesothelioma specialist.

Mesothelioma symptoms result from the cancer itself and may overlap with side effects caused by cancer treatment. Side effects of cancer treatment usually fade away after the treatment ends. Mesothelioma symptoms tend to progress along with the cancer. Symptom management is critical to quality of life.

Talk to your oncologist about working with a palliative care specialist. These doctors specialize in managing symptoms and improving quality of life. Many cancer centers now offer palliative care to patients undergoing treatment, even those participating in clinical trials.

Rebuilding and getting back to normal isnt a race for the swift. Its for those who can endure the highs and lows. There are small victories and setbacks. But eventually, the battle is won.

Registered Nurse and Patient Advocate

Karen Selby joined Asbestos.com in 2009. She is a registered nurse with a background in oncology and thoracic surgery and was the regional director of a tissue bank before becoming a Patient Advocate at The Mesothelioma Center. Karen has assisted surgeons with thoracic surgeries such as lung resections, lung transplants, pneumonectomies, pleurectomies and wedge resections. She is also a member of the Academy of Oncology Nurse & Patient Navigators.

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Last Modified March 15, 2019

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Mesothelioma Symptoms: Asbestos Cancer Warning Signs

What is Mesothelioma Cancer? | Mesothelioma Book

Mesothelioma is a cancer found in the lining surrounding the lungs, the stomach, the heart or the testicles. This cancer takes its name from the name that is given to this lining - the mesothelium. The pleura is the name for the mesothelial tissue surrounding the lungs and lining the chest cavity. If the cancer is in this lining, it is called "pleural mesothelioma." Pleural mesothelioma is the most common type of mesothelioma.

The peritoneum is the lining that covers most of the organs in the abdominal cavity, while the pericardium is the lining that covers and protects the heart. If the cancer is in either of these areas, it is called "peritoneal mesothelioma" or "pericardial mesothelioma."

Like other forms of cancer, mesothelioma occurs when cells become abnormal and divide or grow out of control. When someone has mesothelioma, the lubricating fluid in the lining may be over-produced. This excess fluid encases the organs with a thick layer of tumor tissue, described as a rind type of layer, that puts pressure on the organs. People with pleural mesothelioma often complain of shortness of breath and a buildup of fluid in the chest area. In advanced cases of mesothelioma, cells metastasize, or grow and invade other organs and spread to other areas of the body.

The only agreed upon cause of mesothelioma is exposure to asbestos.

It often takes 10 to 60 years after exposure to asbestos before the symptoms of mesothelioma develop.

This period of time is referred to as a latency period. Because of the latency period, the disease commonly affects men and women that are at least 50 years of age and that worked with asbestos between 10 and 60 years ago.

However, there are many known cases of people developing mesothelioma at an earlier age. Often these are the sons and daughters whose parents were exposed to asbestos and who unwittingly brought the invisible dust home on their clothes or who did home remodeling projects and used products, such as joint compound, that contained asbestos. In some cases the child was around the parent as the parent changed the brakes - lined with asbestos - in the family car. This is called secondary exposure to asbestos.

Many people working 10 to 60 years ago were not required to use any type of protection in the workplace while they were exposed to asbestos even though the companies that manufactured the products containing asbestos had full knowledge that it was dangerous and that exposure to it would harm the health of many of the workers.

As with other cancers, a speedy diagnosis is important to effective treatment of mesothelioma. If you believe that you may have mesothelioma and that you worked with asbestos in the past, you should inform your doctor of this fact.

If you wish to learn more about mesothelioma, CLICK HERE to receive a free book written by medical professionals who have treated mesothelioma.

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What is Mesothelioma Cancer? | Mesothelioma Book

Mesothelioma Symptoms – Critical Signs to Watch For

Patients in the early stages of pleural mesothelioma do not exhibit many symptoms. Those that do show are not specific to the disease. Mesothelioma symptoms common in the early stages are:

These are similar to symptoms of various other disorders, such as pneumonia, common cold, asthma, influenza, and Chronic Obstructive Pulmonary Disease (COPD). Pleural effusions and inflammation in the lining of the lungs are the main source of discomfort associated with mesothelioma, but are also linked to pneumonia and COPD.

Up to 25 percent of patients have symptoms like dyspnea and chest pain for approximately 6 months before seeing a doctor.

Pleural thickening is another result of pleural mesothelioma that is common in other diseases. This is caused by the scarring of the pleura. It causes a loss of elasticity in the lungs, which is essential for the lung to expand for normal breathing.

Pleural thickening can also be caused by tuberculosis, pleurisy, and empyema (infection in the lung that causes a buildup of pus in the pleura). However, in mesothelioma, this is specifically caused by scarring of the pleura due to asbestos.

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Mesothelioma Symptoms - Critical Signs to Watch For

Mesothelioma | Causes, Symptoms, Treatment, Prognosis

Malignant mesothelioma, often referred to simply as mesothelioma, is a type of cancer that affects the mesothelium the protective lining of the lungs, abdomen, and heart. It is caused by exposure to asbestos. Asbestos is a carcinogenic mineral that was used for decades in a number of industrial, commercial, military, and residential applications. Mesothelioma is the most severe of all asbestos-related illnesses.

Due to its long latency period the time between exposure to asbestos and the development of the disease mesothelioma is usually diagnosed at advanced stages and often occurs in older people. It is more common in men, especially those who worked in the automotive and construction industries or who served in the armed forces. First responders, such as firefighters, police officers, paramedics, and EMTs, also have an increased risk of developing the disease.

While the prognosis has been historically poor, advancements in treatment options offerpatients newfound hope for longer survival and a better quality of life.

Doctors diagnose 3,300 new cases of mesothelioma each year.

Due to the high number of occupational-exposure cases, patients may be eligible to receive discounted treatment or financial compensation.

The only known cause of mesothelioma is exposure to asbestos. When inhaled, tiny asbestos fibers lodge in the bodys mesothelium. Years after initial exposure, these have the potential to form malignancies. Learn more about what causes mesothelioma.

Mesothelioma occurs as a result of inhaled or ingested asbestos fibers. Common symptoms may mirror less severe conditions, such as the flu or pneumonia. These include shortness of breath, fever, chest pain, wheezing or a cough, and weight loss. Patients exhibiting symptoms should visit their doctor right away. The earlier it is diagnosed, the better the prognosis, as more extensive treatment offerings are usually available. Learn more about the symptoms of mesothelioma.

Diagnosing mesothelioma is difficult, as its symptoms are often mistaken for other conditions. Doctors also struggle to diagnose the disease because of its rarity and because of its extremely long latency period. Doctors use imaging scans, blood tests, and biopsies when identifying the presence and stage of cancer. A biopsy is the only definitive way to diagnose it. It is important to get a second opinion when going through the diagnostic process. Learn more about how doctors diagnose mesothelioma.

There are three primary types of mesothelioma: pleural, peritoneal, and pericardial. Pleural accounts for the majority of cases, followed by peritoneal. Pericardial is extremely uncommon, accounting for less than 5 percent of all cases. The location of mesothelial tumors in the body is a major determinant of courses of treatment. Learn more about the three types of mesothelioma.

The type of cell present in mesothelioma tumors can significantly affect a patients prognosis and treatment options. Tumors are categorized either as epithelioid, sarcomatoid, or a combination of the two, referred to as biphasic. Learn more about mesothelioma tumor cell types.

Mesothelioma, like other cancers, is staged from 1 to 4. Stages 1 and 2 are less severe and more treatable.Advanced stages have a poor prognosis, as thedisease becomes more difficult to treat.

The stage at which you are diagnosed can affect your treatment options and prognosis. Learn more about the four stages of mesothelioma.

Treatment for mesothelioma varies, primarily based on the type, stage, and cell type of each patients unique case. Generally, doctors combine chemotherapy, radiation, and surgery to create a specialized multimodal treatment plan. When it comes to differences in care, curative treatment options aim to completely eradicate the cancer. Often this is only available in early-stage diagnoses. Palliative care refers to treatment options that seek to relieve patient pain and discomfort.

New treatments and advancements in current treatments offer patients hope of fighting the disease.

Your overall health can have a significant impact on your mesothelioma prognosis and life expectancy. Some ways to improve your prognosis include a healthy diet, exercise, and reducing stress. Learn more about how lifestyle changes may help improve your prognosis.

Negligent asbestos exposure accounts for half of all occupational cancer deaths. Unfortunately, asbestos companies and employers knew the dangers of asbestos and still placed the health of their employees at risk. Asbestos trust funds exist to compensate victims of wrongful occupational exposure, totaling an estimated $37 billion. If you or a loved one has mesothelioma, you may be eligible for financial assistance to help recover lost wages and cover the burdensome costs of treatment. Learn more about mesothelioma legal compensation.

Veterans account for nearly 30 percent of all mesothelioma cases. Why so high? The military used asbestos extensively during the mid-1900s in everything from ships and submarines to aircraft and even military barracks and mess halls. As a result, many service members (as well as civilian personnel) encountered carcinogenic asbestos dust and fibers. If you served in the military and have mesothelioma or another asbestos-related illness, you may be eligible to apply for VA benefits. Learn more about mesotheliomaand veterans, including how to file a VA claim.

Author

Brittany Nelson

Brittany Nelson holds a BSBA in Marketing from the Daniels College of Business at the University of Denver. As someone whose life has been touched by cancer, she strives to connect those affected by mesothelioma with the support and resources they need to overcome a life-changing cancer diagnosis. Brittany is a proud Denver native. When she isnt sipping coffee, researching, and writing for the site, you can catch her noshing at a new restaurant or trying to hold a handstand in the yoga studio. Note: Brittany is not a medical professional.

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Mesothelioma | Causes, Symptoms, Treatment, Prognosis

Mesothelioma Group | Understanding Mesothelioma Cancer …

Whether youre a mesothelioma patient, family member, or friend, were here to guide you through every step of the diagnostic and treatment process. Were a small team of caring healthcare professionals, patient advocates, and communication specialists dedicated to helping you and your loved ones understand what is mesothelioma, where and when was your exposure to asbestos, and what are your treatment options. At Mesothelioma Group, we believe that everyone needs an advocate who can provide valuable resources and practical advice to empower the decision making prcess for those who have been affected by this disease.

We are a community dedicated to those that have been impacted by Mesothelioma. Our support group strives to improve your prognosis and raise mesothelioma awareness. Mesothelioma is a complex disease, but getting the best possible care should not be.

We research to provide top-notch medical materials and community support for those impacted by Mesothelioma. Our team is dedicated to providing personalized information, resources, and support for caregivers, patients and their loved ones.

We believe in building awareness for mesothelioma as well as educating mesothelioma patients and their loved ones. Our team will provide resources for treatment and the latest mesothelioma news to help guide your decisions related to your specific needs.

We understand the outlook with a mesothelioma diagnosis, but do not believe it is the end of the story with advancements in medical treatments, information accessibility, and support from within our community. You are not alone with your prognosis.

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Mesothelioma Group | Understanding Mesothelioma Cancer ...

Mesothelioma – Cancer Tutor

There are different names for mesothelium depending on where it is in the body: pleura lungs peritoneum inside the abdomen including organs within pericardium heart tunica vaginalis testicles

Tumors in the mesothelium can grow on any of the above membranes. Mesothelioma is a tumor that grows on the mesothelium. Tumors are not always cancerous but can be.

Researchers believe there is a combination of factors that contribute to the cause of mesothelioma.

The main cause of pleural mesothelioma is exposure to asbestos. That said, the majority of people who have experienced asbestos exposure, even in large quantities, do not contract mesothelioma.

Risk factors of Mesothelioma include: asbestos exposure zeolites exposure radiation exposure

Other possible risk factors include: SV40 Simian virus 40

Factors not associated with mesothelioma: smoking

In the early stages, mesothelioma may present no symptoms. In the case of pleural mesothelioma, symptoms may not present for up to 20 to 40 years after asbestos exposure. Often, symptoms will present when a tumor grows and invades surrounding organs. Some of the following symptoms can be caused by things other than mesothelioma, so it is important to visit your physician for a proper diagnosis.

Symptoms can vary depending on where the mesothelioma is located.

Symptoms of pleural mesothelioma include: pain in the chest area shortness of breath hoarseness difficulty swallowing persistent cough edema of face and arms weight loss fever / sweating fatigue

Symptoms of peritoneal mesothelioma include: swelling of the abdomen pain in the abdomen mass in the abdomen or pelvis weight loss / loss of appetite bowel blockage nausea / vomiting fever

People with African or Asian ancestry ar less likely to develop mesothelioma than whites or Hispanics. The risk for mesothelioma rises with age, with 69 years of age being the average age of diagnosis. Men have a 5-fold higher risk for developing mesothelioma. This may be related to the type of work both men and women typically participate in, with men working jobs that have a higher risk for exposure to asbestos.

Because mesothelioma is generally not found in the early stages, the survival rates are generally poor.

5-Year Survival Rates for Mesothelioma: Stage I- IV 5-10 percent

Median Survival Rates for Mesothelioma: Stage I 21 months Stage II 19 months Stage III 16 months Stage IV 12 months

The Bob Beck Protocol is the primary recommended treatment for Mesothelioma because it is effective in killing microbes in the bloodstream. The Dirt Cheap Protocol is an alternative to the High RF Frequency Protocol, particularly if cost is an issue. Due to the fact that new microbes are ingested into the body when someone eats, the protocols for mesothelioma should be considered for life-long maintenance and used, as necessary.

Primary: Bob Beck Protocol Required Secondary: Liver and Kidney Flush Also Consider: High RF Frequency Protocol, Ultraviolet Light Protocol, Dirt Cheap Protocol, Killing Microbes, Bill Henderson Protocol

Conventional medicines main types of treatment for Mesothelioma include: Surgery Radiation therapy Chemotherapy Regular Follow Ups Palliative therapy

By far, the largest contributing factor for mesothelioma is being exposed to asbestos, so try to minimize exposure as much as possible.

The immune system contains many different types of cells, however, only a handful of these white blood cells actually kill cancer cells. It should be the intent of a person with cancer to focus on treatments that quickly increase the count of the cancer-killing white blood cells.

The second thing to note is that building the immune system is sometimes not the highest priority of those with cancer. People with only a few months to live should definitely take immune system building products and focus more on the nutrients, foods and products that kill cancer-cells directly, such as the Grape Cure, Noni Juice, Essiac Tea, etc. or revert the cancer cells into normal cells.

With rare exceptions, it is highly advisable to use natural substances to deal with the immune system to treat cancer, no matter what stage the cancer patient is in.

A healthy immune system remains your body's best defense. Not only is a weak immune system a major reason patients have cancer and cancer itself can further weaken the immune system.

Beta glucans help regulate the immune system, making it more efficient. In addition, beta glucans stimulate white blood cells (lymphocytes) that bind to tumors or viruses and release chemicals to destroy it.

Beta Glucan has been approved in Japan, Australia, South Korea, and Taiwan as an immunoadjuvant therapy for cancer. In fact, helping with cancer is just the beginning with Beta Glucan. There have thousands of studies showing the product can protect against infections, lower your cholesterol, lower blood sugar, reduce stress, increase your antibody production, heal wounds, help radiation burns, overcome mercury-induced immunosuppression (like Thimerosal, used as a preservative in vaccines), help with diabetes, and even naturally prevent metastasis (or the spreading of your cancer).

Harvard Medical School suggests following general good-health guidelines is the single best step you can take toward keeping your immune system strong and healthy:

Don't smoke. Eat a diet high in fruits, vegetables, and whole grains, and low in saturated fat. Exercise regularly. Maintain a healthy weight. Control your blood pressure. If you drink alcohol, drink only in moderation. Get adequate sleep. Take steps to avoid infection, such as washing your hands frequently and cooking meats thoroughly. Get regular medical screening tests for people in your age group and risk category.

More Information: Building the Immune System

Your diet plays a role in a healthy immune system. The top vitamins your immune system needs to perform include:

Vitamin C helps to repair and regenerate tissues and aids in the absorption of iron Vitamin E a powerful antioxidant that helps your body fight off infection Vitamin B6 supports adrenal function and is necessary for key metabolic processes Vitamin A aids immune function and helps provide a barrier against infections Vitamin D modulates cell growth, promotes neuromuscular and immune function, and reduces inflammation Folate key in development of red blood cells (a lack of Folate can make the body susceptible to cancer) Iron helps your body carry oxygen to cells Selenium slows the body's over-active responses to certain aggressive forms of cancer Zinc slows the immune response and control inflammation in your body

MORE ON MESOTHELIOMA

Sources: American Cancer Society, National Cancer Institute, Cancer Research Society

Why stop learning here when there are several great discussions on Mesothelioma going on right now in the forum.

Go to the forum

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Mesothelioma - Cancer Tutor

Mesothelioma | pathology | Britannica.com

Mesothelioma, a tumour that arises from the sheet of cells known as the mesothelium, which lines body cavities and forms the tissue layers referred to as the pleura and the peritoneum. The pleura is located in the chest cavity, either lining the chest wall (parietal pleura) or covering the lung (visceral pleura), and the peritoneum is the corresponding tissue in the abdomen. Roughly 75 percent of mesothelioma cases originate in the chest. Mesothelial cells can also be found in other areas of the body, such as the scrotal sac and the pericardium (the sac surrounding the heart), and in rare cases the tumour may arise primarily in those locations.

Some 2,000 to 3,000 cases of mesothelioma are diagnosed annually in the United States and more elsewhere around the world, related in part to asbestos exposure rates. For males born between 1945 and 1950 in western Europe, researchers projected that mesothelioma during the period from 1995 to 2029 would reach rates as high as 1 in 150 because of asbestos exposure in this population.

There is an unequivocal association with asbestos exposure in about 80 percent of cases. The latency period between exposure and the development of disease typically ranges from 20 to 50 years, with an average of about 30 years. Other causative agents, such as SV40 (simian virus 40), have been postulated; however, data are inconclusive. Some cases are idiopathic, in which no known cause can be identified. Use of asbestos was strictly regulated in the United States beginning in the latter part of the 20th century, though it is still used in the developing world. Erionite, which is similar to asbestos, is found in the soil in Turkey and is associated with concomitant pockets of high mesothelioma incidence. The biology of asbestos exposure and subsequent development of cancer is not clearly understood, because of the long latency period. However, a chronic inflammatory reaction, causing DNA damage to the mesothelial cells, is likely involved. Unlike lung cancer, the eventual development of mesothelioma is not associated with smoking.

The diagnosis of mesothelioma usually occurs at advanced stages, because the thin layer of tumour that develops may not be discernible in X-rays, nor may it lead to symptoms. The most common complication leading to an eventual diagnosis is pleural effusion (a collection of fluid around the lung in the pleural space), whereby a person becomes short of breath. Pain is common with more-advanced disease, when the tumour invades the ribs and muscles of the chest wall. The use of computed tomography (CT; computerized axial tomography) is essential to determine the extent of disease and the stage of tumour development. CT scanning is also used to determine whether the patient might be considered a candidate for surgery. Positron emission tomography (PET) is useful to assist in the determination of metastasis (spread) to other areas of the chest or body. Serum biomarkers, such as mesothelin, osteopontin, and megakaryocyte potentiating factor, have shown some promise for the development of blood tests to screen for the disease, as well as for following patients for evidence of recurrence after treatment.

There are many subtypes of mesothelioma, based on microscopic pathologic examination. The most common subtype is epithelial mesothelioma, followed by biphasic, or mixed, disease, which has epithelial and sarcomatous (connective tissue) involvement; less common is the solely sarcomatoid subtype. The pathologic diagnosis of mesothelioma, using microscopic techniques, can be difficult and often requires that a battery of immunohistochemistry (IHC) tests be performed on each tumour to determine whether it is mesothelioma or perhaps another type of tumour that has spread to the thoracic or abdominal cavity. IHC uses colorimetric antibodies directed at proteins on the surfaces of cells. A pattern of both positive and negative staining is interpreted by the pathologist. Some of the more common positive-staining antibodies that are used include WT1 (Wilms tumour 1) and mesothelin and cytokeratin 5/6. Commonly used negative-staining epithelial antibodies include CEA (carcinoembryonic antigen), LeuM1, and TTF-1 (thyroid transcription factor 1).

Reported survival for patients with mesothelioma has been relatively poor, ranging in most cases from 9 to 18 months with or without treatment. Factors used to predict survival include epithelial subtype, involvement of regional (mediastinal) lymph nodes, and size of the tumour. The ability to completely remove the tumour at surgery and the use of multimodality (surgery, chemotherapy, and radiation therapy) in some combination-therapy approaches can also influence survival.

Advances in multimodality therapy have included the use of a class of chemotherapy drugs referred to as folate antimetabolites. The most common drug used in this class is pemetrexed, which is most effective when combined with platinum-based agents, such as cisplatinum. These drugs may be given as definitive treatment to patients that are not surgical candidates, and up to 50 percent of treated individuals may respond with tumour arrest and shrinkage and modestly improved survival. Clinical trials have evaluated the use of these drugs prior to surgery (neoadjuvant therapy). The weight of evidence indicates that surgical removal of the tumour is important for improved survival, but only if surgery is included with other therapies. Care must be taken when determining whether a patient should undergo surgery, since many patients are at advanced age.

Removal of the tumour alone from the surfaces on which it is growing (a procedure known as pleurectomy) may be best in early-stage patients. A more aggressive operation, extrapleural pneumonectomy (EPP), may be required in more-advanced cases. EPP involves the removal of tumour, pleura, diaphragm, and pericardium, with reconstruction of the latter two structures. The tumour grows over a very large surface area, and for that reason the risk of local recurrence following surgery is high. Many modalities have been evaluated and are being used for adjuvant (after surgery) treatment, including heated chemotherapy instillation (gradual introduction of liquid drug into cancerous tissue), photodynamic therapy (administration of a drug that becomes active when the cancerous tissue is exposed to a certain form of light), and various forms of radiation therapy. Local control over the administration of therapy can be made more precise by the use of computerized conformal radiation therapy techniques, such as intensity-modulated radiation therapy, in which three-dimensional CT is used to guide the delivery of very precise doses of radiation to the tumour or to parts of the tumour.

A number of experimental approaches to treatment capitalizing on the presence of biological or molecular targets have been attempted. Some promising future targets identified in clinical studies have included proteins (e.g., mesothelin) that are commonly found on mesothelioma cells. Growth factors, antiangiogenic drugs, which block the growth of tumour blood vessels, and molecules that stimulate programmed cell death (apoptosis) have also been investigated.

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Mesothelioma | pathology | Britannica.com

What is Mesothelioma? Learn About Causes, Survival Rates …

What is Mesothelioma?

Mesothelioma is a rare and aggressive disease that is known to develop over a period of 20 to 40 years. In many cases, the disease is not diagnosed until the end stage, when it is more difficult to treat. There is no cure for mesothelioma, but advanced medical treatments have allowed patients to live longer with the disease. Up to 3,000 people a year are diagnosed with mesothelioma.

Malignant mesothelioma is cancer that forms in the mesothelium, or the thin layer of cells that surround major organs. Mesothelioma is almost always caused by exposure to asbestos. There are three common locations for mesothelioma to form:

In general, the average life expectancy for mesothelioma patients is between 12 to 21 months. Some 40 percent of patients survive about a year after a diagnosis and about 20 percent live more than two years following a diagnosis. While rare, there are some patients who live longer than five years with the disease.

The patients age at diagnosis, general health and access to treatment specialists are among the many factors that go into determining a mesothelioma patients life expectancy. Other factors that play a key role are the location of the disease (pleural mesothelioma patients have better survival rates than other disease locations), cell types involved (epithelial cells respond better to treatment than other types) and stage (earlier stage disease is more responsive to treatment). Experts warn that life expectation estimations vary greatly by patient and individual circumstances.

The primary cause of any form of mesothelioma is exposure to the thin, fibrous mineral called asbestos. When asbestos fibers are inhaled, they travel through the lungs to reach the pleura, where they cause inflammation and scarring to form pleural mesothelioma. In cases of peritoneal and pericardial mesothelioma, researchers suspect asbestos fibers are ingested, travel through the lymph system or are absorbed through the skin to irritate surrounding cells. In all cases, the irritations damage cell DNA, causing cells to grow rapidly and abnormally and forming tumors.

Small studies have indicated some people are genetically predisposed to developing mesothelioma because they are more susceptible to the dangers of asbestos. Researchers are also reviewing a link between mesothelioma and Simian virus 40 (SV40), a DNA virus that contaminated early polio vaccines. There has been no definitive link between the virus and mesothelioma.

Physicians determine the stage of disease by performing numerous tests including X-rays, CT (CAT) scans, MRIs, PET scans and biopsies. It is important to determine where the cancer started and if it has spread from the point of origin for a correct disease staging. An accurate assessment of disease stage is crucial to successful treatment options.

Most physicians use a universally accepted tumor grading system to stage the disease. This allows physicians to communicate about a single patient to devise the best treatment plan. The TNM system looks at the size and growth of tumors (T), the involvement of lymph nodes (N) and the metastasis, or spread, of the disease (M). From there, the cancer is staged, with stages I and II as the early disease process and stages III and IV as the more advanced disease. Most cases of mesothelioma are diagnosed in the later stages, making treatment difficult.

About 55 percent of mid- to late-stage mesothelioma patients live six months after a diagnosis, some 40 percent survive the first year after a diagnosis and about 9 percent survive five years or longer. An overall survival rate is dependent on a number of factors including state and location of the disease, the patients age and general health and the access to treatment specialists. Long-term survivors credit lifestyle changes, alternative medicine and treatment from mesothelioma specialists as contributing factors to their success.

A recent study that looked at 20 years of survivor information, from 1992 to 2012, found pleural and peritoneal survivorship was on the rise. The study found recent advances in treatment, including hyperthermic intraperitoneal chemotherapy (HIPEC) and cytoreductive surgery, appear to have increased survival rates in peritoneal mesothelioma patients. The studys author suggested genetics, various treatment modalities and gene environment interactions might also play a part in patient longevity.

The optimal treatment approach for most mesothelioma patients is multimodal therapy which is surgery, chemotherapy and radiation. This approach, if successful, eliminates diseased tissue and allows for palliative care. Your treatment plan will depend on your diagnosis, disease stage and overall health.

For decades, all branches of the military required asbestos be used to protect service members from heat, fire and chemical threats. It was widely used in barracks, offices, vehicles and vessels. Over a period of 50 years, some 5 million veterans were exposed to asbestos in shipbuilding operations alone. About 30 percent of mesothelioma patients are U.S. military veterans. Occupations that include carpentry, construction, roofing, auto mechanics and milling are at risk for exposure to dangerous levels of asbestos.

It is estimated that more than 300 asbestos products were used on military installations and in military applications between the early 1930s and the late 1970s. More recently, soldiers serving in Iraq, Afghanistan and the Middle East may be been exposed from airborne asbestos. Companies that produced these products concealed the dangers of mesothelioma to put profits ahead of the safety and well being of our troops.

Gender, age, severity of symptoms, level of asbestos exposure, stage of disease and disease cell type play a significant role in the overall prognosis for mesothelioma patients. In addition, external factors including diet, age, stress level and general health play a role. The average pleural mesothelioma patient with late-stage disease survives about 12 months after a diagnosis, but those treated with surgery and radiation may extend their prognoses by some 28 months. Peritoneal mesothelioma patients who are treated with heated intraperitoneal chemotherapy (HIPEC) outlive their prognoses by 24 months to 7 years.

Many patients are able to improve their prognosis by seeking treatment options from a qualified mesothelioma specialist. Doctors who are practiced and trained in mesothelioma disease treatment approaches have specialized skills, education and access to crucial information that can make positive changes on long-term health.

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What is Mesothelioma? Learn About Causes, Survival Rates ...

Mesothelioma Cancer | Symptoms, Prognosis, & Treatment

Asbestos has long been prized for resistance to heat and electricity and for its durability, strength, and flexibility. These properties gave it many uses in all kinds of industries, but it has since been proven that long-term exposure to its fibers posesserious health risks, including mesothelioma.

Due to its widespread use in the U.S. and throughout the world, hundreds of millions of people have been and still are exposed to harmful asbestos. Many of these people have developed mesothelioma, a type of cancer that only shows symptoms decades after the exposure occurred.

Mesothelioma is a type of cancer that begins in the tissuethis is called the mesotheliumthat lines organs in the body. The most common type of this cancer is pleural mesothelioma, in which tumors form in the tissue around the lungs. Asbestos fibers that are inhaled stick in this tissue and cause damage over decades. Other types of mesothelioma attack the peritoneum in the abdominal cavity or the pericardium around the heart.

Malignant mesotheliomatakes decadessometimes up to 50 yearsto develop after exposure to asbestos, and because it is rare with symptoms similar to more common illnesses, diagnosis is often delayed.

Symptoms of pleural mesotheliomainclude shortness of breath, chest pains, and persistent dry coughing. As the disease advances to its final stage, symptoms can become more severe and typically include severe chest and lung pain, bloating, fatigue, skin rashes, nausea, vomiting, abdominal pain, night sweats, and fever.

If you or a loved one has been diagnosed with mesothelioma, asbestos-related lung cancer, or asbestosis, you may be entitled to substantial compensation.Fill out our form to receive a freeFinancial Compensation Packet. Our packet is loaded with information on leading mesothelioma attorneys in your area, how to file a claim for asbestos trust funds, how to get paid in 90 days, and more.

Most mesothelioma victims are people who worked with or around asbestos. Men and women who served in themilitary, construction workers, shipyard workers, and industrial workers are among those most at risk. Anyone who lived with someone who worked with asbestos may develop mesothelioma after being exposed to fibers brought home on the workers clothing.

U.S. Navy veterans have some of the highest rates of mesothelioma in the country. American naval vessels built from the 1930s to the early 1960s contained large amounts ofasbestos. Floors, hulls, electrical systems, insulation, boilers, steam pipes, and more contained asbestos fibers in order to add tensile strength, heat resistance, and low electrical conductivity.

Other types of workplaces likely to have contained asbestos include power plants, steel plants, manufacturing facilities, oil companies, welding business, automotive shops, chemical plants, mines and processing plants, and textile mills.

Mesothelioma is a rare type of cancer. Not everyone who was exposed to asbestos will develop the cancer, although exposure is the leading cause. The demographic most likely to be diagnosed is older men, those who worked decades ago in facilities with asbestos.

It can take decades to accuratelydiagnose mesothelioma. Symptoms may not be obvious for 20 to 50 years after exposure. Even then, the symptoms may initially seem mild and mimic those of pneumonia, the flu, and other common illnesses. It is important for physicians to know if patients with mesothelioma-like symptoms may have been exposed to asbestos in the past in order to make the most accurate diagnosis or to refer patients to the right specialists.

After a physical exam, diagnosis will likely involve blood tests, X-rays, and other types of imaging scans. If tumors or growths are seen in scans, the next step is to perform a biopsy. A small piece of tissue is removed to be examined under a microscope. This is usually the most conclusive way to determine if growths are cancerous. After mesothelioma is diagnosed, a specialist will stage the disease.

Mesothelioma, like other cancers, is assigned one of four stages at the time of diagnosis to describe how advanced it is:

Mesothelioma cancer currently has no cure, which means that theprognosisis not usually positive. Additionally the prognosis is often not very good because most cases of mesothelioma are diagnosed in the latter stages, when treatment options are limited.

Its important to remember, however, that each patient is different and while one person may survive a year, another person may go on to live decades. Its imperative to work with your physician on the best treatment options for you and your unique situation.

Chemotherapy, radiation, surgery, or some combinations have proven to be the most effectivemesothelioma treatmentsso far. Whenever possible, surgery is used to remove as much of the cancerous tissue as possible. Patients who are not good candidates are those whose cancer is in stage 3 or 4, who are elderly, or who are in poor physical condition or poor health.

Patients who undergo surgery are then usually given chemotherapy or radiation to try to eliminate any remaining cancer cells. Those who cannot have surgery may be given either or both of these treatments to slow the spread of the cancer and extend life.

Research into mesothelioma is ongoing, and there are some exciting emerging treatments that may help more patients in the future:

In addition to traditional medical treatments, many mesothelioma patients can benefit from a range of complementary and alternative therapies. Specific herbs and vitamins, acupuncture, yoga, meditation, and holistic healing, among others may be useful in reducing symptoms and making patients more comfortable.

Remember to fill out our from to get your free Financial Compensation Packet, with information on top asbestos and mesothelioma lawyers in your area. Keep in mind that if you havemesothelioma, asbestos-related lung cancer, or asbestosis, you may be eligible for considerable compensation. For additional assistance, contact us at800-793-4540.

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Mesothelioma Cancer | Symptoms, Prognosis, & Treatment

Mesothelioma: What are it’s Causes, Symptoms & Prognosis …

What is asbestosis disease?

Asbestosis disease is a chronic lung condition that is caused by inhaling asbestos fibers.

The asbestos fibers lodge in tiny sacs in the lungs, known as alveoli. Symptoms of asbestosis include shortness of breath, tightness and pain in the chest, chronic cough, loss of appetite, weight loss, and clubbing of fingers and toes.

Treatment can include use of an oxygen tube or mask, pulmonary rehabilitation exercises, or a lung transplant in extreme cases.

No. Although both of these diseases, along with lung cancer, are associated with exposure to asbestos, they are not the same.

Asbestosis is a chronic lung disease, not a cancer. It is caused by inhalation of asbestos fibers, which can get stuck in the small sacs in the lungs. Having asbestosis can increase a patients chances for developing asbestos-related lung cancer.

Malignant mesothelioma is a cancer. It affects the mesothelium tissue, which lines the lungs and chest wall, as well as the abdominal cavity, heart, and testicles. Malignant mesothelioma is caused by the inhalation or ingestion of asbestos fibers, which lodge in the mesothelium tissue.

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Mesothelioma: What are it's Causes, Symptoms & Prognosis ...

Mesothelioma Lawyer Center | Leading Asbestos Attorneys

For over 20 years weve been helping families like yours connect with leading mesothelioma lawyers. There are many law firms that handle mesothelioma and asbestos cases. Choosing the right law firm for your family can be overwhelming. We clear through the confusion and help you connect withonly the top lawyers nearest to you.

There arent enough words to describe how much our family appreciates everything you have done for us since we met 4 years ago. I feel a very special bond between us that will continue for a very long time.~ Marilyn & Family

One of the most important decisions youll make as you fight this terrible disease is choosing the legal professional who will guide and represent you.Mesothelioma and asbestos cases can be complicated and the laws confusing. It is essential to select a legal team that not only specializes in and has experience with these kinds of cases, but also has a proven and successful track record.

Your lawyer should also be someone who makes you feel comfortable. Moving forward with a case you should have no doubts that your legal team has your best interests in mind. Choose the professional who will fight for you, educate you about the laws and how they affect the choices you make, and who will keep you up to date as your case proceeds.

Perhaps most importantly, a good asbestos or mesothelioma lawyer will help you decide what to do in order to get justice and compensation. Whether you should file a claim with an asbestos trust fund, start a lawsuit, go to trial with your case, or seek compensation through the Veterans Administration is a tough decision to make without good legal advice. Learn more about finding an asbestos lawyer.

Mesothelioma trust funds are financial funds that have been set up by companies that faced bankruptcy over asbestos lawsuits. Before being eligible for bankruptcy protection, these companies were required to set up the trusts to compensate victims of asbestos exposure now and in the future.

Today, there are over a hundred asbestos and mesothelioma trust funds set up in the United States alone, and that number may grow as more companies face liability. According to the United States Government Accountability Office (GAO), close to $17.5 billion has already been awarded to victims of diseases caused by exposure to asbestos. An estimated $30 billion is still available for future cases.

In the past, victims of mesothelioma and other asbestos-related diseases had to rely on lawsuits for compensation. But since many companies were ordered to set up mesothelioma trust funds, compensation is now more readily available. Get more information about asbestos trust funds.

An asbestos trust fund is not your only option for getting compensation in the wake of a mesothelioma diagnosis. Filing a lawsuit against the company negligent in your asbestos exposure is another way to seek compensation for medical expenses, pain and suffering, lost wages, and in some instances, punitive damages.

Although there have already been many successful mesothelioma lawsuits brought by asbestos victims in the United States, there are expected to be even more in the coming years. Both in the U.S. and worldwide more people will be diagnosed with asbestos illnesses over the next several years or even decades.

If you or a loved one has been diagnosed with an asbestos-related disease, such as malignant mesothelioma or asbestosis, the first step in getting the substantial compensation you may qualify for is to learn more about how the lawsuit process works and what you may be entitled to receive.Learn more about filing a mesothelioma lawsuit.

The majority of lawsuits for mesothelioma end in settlements rather than in a trial. In a settlement, the plaintiffs representation negotiates a compensation amount with the defendants legal team. Although its difficult to determine how long a settlement will take, they are generally much quicker than going through a court trial and getting a jury verdict.

Mesothelioma settlement amounts vary according to how long the defendant has lived with an asbestos-related illness, the stage and severity of the illness, and the circumstances surrounding how asbestos exposure took place. No lawyer can guarantee you will win a certain amount, but an experienced attorney make a good approximation.

Many mesothelioma cases have resulted in million-dollar settlements, and some settlements have even reached tens of millions of dollars and more for both the defendants and their loved ones. Its important to understand how mesothelioma settlements work so that you know what to expect. Get more information about settlements.

If you served in the U.S. military and you believe your asbestos exposure occurred during service, you may be able to file for and receive compensation through the Veterans Administration (VA). There are certain requirements you need to meet, and you may also qualify for other types of compensation and healthcare. To sort through the complicated process, and to determine what you qualify for, let an experienced mesothelioma lawyer guide you. Learn more about what the VA offers asbestos victims.

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Mesothelioma Lawyer Center | Leading Asbestos Attorneys

Mesothelioma | Memorial Sloan Kettering Cancer Center

Peritoneal mesothelioma affects the tissue (membrane) that covers and helps lubricate your abdominal organs. This tissue also helps keep your abdominal organs in place. Peritoneal mesothelioma accounts for 10 to 20 percent of new mesothelioma cases diagnosed in the United States each year.

In most cases, experts are still not sure why people develop peritoneal mesothelioma. Asbestos and radiation exposure are risk factors. So is having chronic peritoneal inflammation. However, most people have no risk factors.

Because peritoneal mesothelioma is rare, it sometimes goes undiagnosed for long stretches of time. If your doctor suspects that you have the disease, its best to meet with one of our mesothelioma specialists, who are experienced in diagnosing and treating this condition.

He or she will examine you and work with an MSK pathologist with expertise in identifying mesothelioma cells and determining which subtype you may have.

The major subtypes of peritoneal mesothelioma are:

Once your treatment team has identified your subtype, we can prescribe a treatment plan customized for you. For example, within the epithelial subtype alone, there are varying grades of disease. And if you have the subtype known as well-differentiated papillary mesothelioma, you may need limited treatment, such as monitoring with a radiology test.

Learn more about how we customize a treatment plan for you.

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America’s War on Drugs Full Episodes, Video & More | HISTORY

Americas War on Drugs is an immersive trip through the last five decades, uncovering how the CIA, obsessed with keeping America safe in the fight against communism, allied itself with the mafia and foreign drug traffickers. In exchange for support against foreign enemies, the groups were allowed to grow their drug trade in the United States. The series explores the unintended consequences of when gangsters, war lords, spies, outlaw entrepreneurs, street gangs and politicians vie for power and control of the global black market for narcotics all told through the firsthand accounts of former CIA and DEA officers, major drug traffickers, gang members, noted experts and insiders.Night one of Americas War on Drugs divulges covert Cold War operations that empowered a generation of drug traffickers and reveals the peculiar details of secret CIA LSD experiments which helped fuel the counter-culture movement, leading to President Nixons crackdown and declaration of a war on drugs. The documentary series then delves into the rise of the cocaine cowboys, a secret island cocaine base, the CIAs connection to the crack epidemic, the history of the cartels and their murderous tactics, the era of Just Say No, the negative effect of NAFTA, and the unlikely career of an almost famous Midwest meth queen.The final chapter of the series examines how the attacks on September 11th intertwined the War on Drugs and the War on Terror, transforming Afghanistan into a narco-state teeming with corruption. It also explores how American intervention in Mexico helped give rise to El Chapo and the Super Cartels, bringing unprecedented levels of violence and sending even more drugs across Americas borders. Five decades into the War on Drugs, a move to legalize marijuana gains momentum, mega-corporations have become richer and more powerful than any nations drug cartel, and continuing to rise is the demand for heroin and other illegal drugs.

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America's War on Drugs Full Episodes, Video & More | HISTORY

War on Drugs | United States history | Britannica.com

War on Drugs, the effort in the United States since the 1970s to combat illegal drug use by greatly increasing penalties, enforcement, and incarceration for drug offenders.

The War on Drugs began in June 1971 when U.S. Pres. Richard Nixon declared drug abuse to be public enemy number one and increased federal funding for drug-control agencies and drug-treatment efforts. In 1973 the Drug Enforcement Agency was created out of the merger of the Office for Drug Abuse Law Enforcement, the Bureau of Narcotics and Dangerous Drugs, and the Office of Narcotics Intelligence to consolidate federal efforts to control drug abuse.

The War on Drugs was a relatively small component of federal law-enforcement efforts until the presidency of Ronald Reagan, which began in 1981. Reagan greatly expanded the reach of the drug war and his focus on criminal punishment over treatment led to a massive increase in incarcerations for nonviolent drug offenses, from 50,000 in 1980 to 400,000 in 1997. In 1984 his wife, Nancy, spearheaded another facet of the War on Drugs with her Just Say No campaign, which was a privately funded effort to educate schoolchildren on the dangers of drug use. The expansion of the War on Drugs was in many ways driven by increased media coverage ofand resulting public nervousness overthe crack epidemic that arose in the early 1980s. This heightened concern over illicit drug use helped drive political support for Reagans hard-line stance on drugs. The U.S. Congress passed the Anti-Drug Abuse Act of 1986, which allocated $1.7 billion to the War on Drugs and established a series of mandatory minimum prison sentences for various drug offenses. A notable feature of mandatory minimums was the massive gap between the amounts of crack and of powder cocaine that resulted in the same minimum sentence: possession of five grams of crack led to an automatic five-year sentence while it took the possession of 500 grams of powder cocaine to trigger that sentence. Since approximately 80% of crack users were African American, mandatory minimums led to an unequal increase of incarceration rates for nonviolent black drug offenders, as well as claims that the War on Drugs was a racist institution.

Concerns over the effectiveness of the War on Drugs and increased awareness of the racial disparity of the punishments meted out by it led to decreased public support of the most draconian aspects of the drug war during the early 21st century. Consequently, reforms were enacted during that time, such as the legalization of recreational marijuana in a number of states and the passage of the Fair Sentencing Act of 2010 that reduced the discrepancy of crack-to-powder possession thresholds for minimum sentences from 100-to-1 to 18-to-1. While the War on Drugs is still technically being waged, it is done at much less intense level than it was during its peak in the 1980s.

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War on Drugs | United States history | Britannica.com

War on Drugs | Libertarian Party

Libertarians believe that the War on Drugsisineffective, unfair, and immoral. We advocateending it.

The War on Drugs is ineffective at limiting access to dangerous drugs and, instead, empowers dangerous gangs that make incredible fortunes on the black market for these illegal drugs.

The War on Drugs has imprisoned millions of non-violent people. This is unfair to these people and also uses up resources that would be better spent prosecuting and imprisoning people who are violent.

The War on Drugs is largely responsible for the militarization of police forces in America. It has pitted police against citizens and this is unfair to both. Police need to be able to focus onprotecting the American public from violent offenders and fraud.

Lastly, Libertarians believe that it is immoral for the government to dictate which substances a person is permitted to consume, whether it is alcohol, tobacco, herbal remedies, saturated fat, marijuana, etc. These decisions belong to individual people, not the government.

Because of all of these things, Libertarians advocate ending the War on Drugs.

For more information on the pro-liberty approach on this topic, we invite you to watch the following videos from Learn Liberty:

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War on Drugs | Libertarian Party

Ayn Rand’s life & ideas | Ayn Rand, Objectivism | The Atlas …

Details February 26, 2015

Ayn Rand is Americas most controversial individualist. She was a bold woman who produced brilliant worksfusing fiction and philosophy. Her best-selling novels, like Atlas Shrugged and The Fountainhead, have sold millions of copies and continue to influence independent thinkers and celebrities the world over, from Wikipedia's Jimmy Wales to Angelina Jolie and Hugh Hefner.

Rand cut a striking figure, with her long-stemmed cigarette holder and intense gaze. Known for her fearless denunciations of irrationalism, Rand issued blistering critiques of powerful leaders, from the Pope to President Nixon. She could not be pigeon-holed as Right or Left, although she was known for her scathing attacks on Communism and all forms of collectivism.

She penned philosophical non-fiction works of such originality and power that she was credited by a small group of stunned intellectuals as having single-handedly solved an ancient philosophical puzzle. Yet the elite of her day refused to accept her as a legitimate philosopher. She derided them and their ideas; they returned the favor.

The new philosophy which she founded through her books andessays is called Objectivism. It is a philosophy that celebrates the power and potential of the individual, and reveals the principles necessary for developing a flourishing

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Ayn Rand Quotes (Author of Atlas Shrugged) – Goodreads

The man who refuses to judge, who neither agrees nor disagrees, who declares that there are no absolutes and believes that he escapes responsibility, is the man responsible for all the blood that is now spilled in the world. Reality is an absolute, existence is an absolute, a speck of dust is an absolute and so is a human life. Whether you live or die is an absolute. Whether you have a piece of bread or not, is an absolute. Whether you eat your bread or see it vanish into a looter's stomach, is an absolute.

There are two sides to every issue: one side is right and the other is wrong, but the middle is always evil. The man who is wrong still retains some respect for truth, if only by accepting the responsibility of choice. But the man in the middle is the knave who blanks out the truth in order to pretend that no choice or values exist, who is willing to sit out the course of any battle, willing to cash in on the blood of the innocent or to crawl on his belly to the guilty, who dispenses justice by condemning both the robber and the robbed to jail, who solves conflicts by ordering the thinker and the fool to meet each other halfway. In any compromise between food and poison, it is only death that can win. In any compromise between good and evil, it is only evil that can profit. In that transfusion of blood which drains the good to feed the evil, the compromise is the transmitting rubber tube. Ayn Rand, Atlas Shrugged

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Ayn Rand Quotes (Author of Atlas Shrugged) - Goodreads

Tesla Model Prices, Photos, News, Reviews and Videos – Autoblog

It's almost impossible to separate the audacious reality of Tesla, elevating the EV from an unsexy commuter appliance to a powerful and luxurious statement of success, from its indomitable founder, Elon Musk. The company, like the founder, thrives on publicity that raises the profile of the whole enterprise. The Model S was tipping point, since the earlier Roadster was a niche product, providing serious real-world range and a huge network of ultra-fast chargers; accomplishments no full-line automakers have fully rivaled to date. The Model X SUV with its novel falcon doors came next, and more recently, the Model 3. As of this writing, the Model 3 is in limited production and is experiencing some quality-control hiccups. If Model 3 production can ramp up as Musk expects, Telsa is poised to perhaps secure its future. Whatever Tesla's fate, its meteoric rise as a purveyor of fast, green American sedans and SUVs has been incredible.

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