Complementary And Alternative Medicine Market Applications, Types and Future Outlook Report 2020-2027 – Bulletin Line

New Jersey, United States,- The research report on Complementary And Alternative Medicine market comprises of insights in terms of pivotal parameters such as production as well as the consumption patterns alongside revenue estimations for the projected timeframe. Speaking of production aspects, the study offers an in-depth analysis regarding the manufacturing processes along with the gross revenue amassed by the leading producers operating in this business arena. The unit cost deployed by these producers in various regions during the estimated timeframe is also mentioned in the report.

Significant information pertaining to the product volume and consumption value is enlisted in the document. Additionally, the report contains details regarding the consumption graphs, Individual sale prices, and import & export activities. Additional information concerning the production and consumption patterns are presented in the report.

In a word, the Complementary And Alternative Medicine Market report provides major statistics on the state of the Complementary And Alternative Medicine industry with a valuable source of guidance and direction for companies and individuals interested in the market. In the end, Complementary And Alternative Medicine Market report delivers a conclusion which includes Research Findings, Market Size Evaluation, Global Market Share, Consumer Needs along with Customer Preference Change, Data Source. These factors will raise the growth of the business overall.

Regions Covered in the Global Complementary And Alternative Medicine Market:

The Middle East and Africa (GCC Countries and Egypt)

North America (the United States, Mexico, and Canada)

South America (Brazil etc.)

Europe (Turkey, Germany, Russia UK, Italy, France, etc.)

Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Highlights of the Report:

Accurate market size and CAGR forecasts for the period 2020-2026

Identification and in-depth assessment of growth opportunities in key segments and regions

Detailed company profiling of top players of the global Complementary And Alternative Medicine market

Exhaustive research on innovation and other trends of the global Complementary And Alternative Medicine market

Reliable industry value chain and supply chain analysis

Comprehensive analysis of important growth drivers, restraints, challenges, and growth prospects

The scope of the Report:

The report offers a complete company profiling of leading players competing in the global Complementary And Alternative Medicine marketwith a high focus on the share, gross margin, net profit, sales, product portfolio, new applications, recent developments, and several other factors. It also throws light on the vendor landscape to help players become aware of future competitive changes in the global Complementary And Alternative Medicine market.

Reasons to Buy the Report:

About Us:

Market Research Intellect provides syndicated and customized research reports to clients from various industries and organizations with the aim of delivering functional expertise. We provide reports for all industries including Energy, Technology, Manufacturing and Construction, Chemicals and Materials, Food and Beverage, and more. These reports deliver an in-depth study of the market with industry analysis, the market value for regions and countries, and trends that are pertinent to the industry.

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Complementary And Alternative Medicine Market Applications, Types and Future Outlook Report 2020-2027 - Bulletin Line

Brazil Complementary And Alternative Medicine Market Segments and Supply Demand Forecast 2020-2027 – Bulletin Line

The report covers the forecast and analysis of the Brazil Complementary and Alternative Medicine market on a global and regional level. The study provides historical data from 2015 to 2018 along with a forecast from 2019 to 2027 based on revenue (USD Million).

The study includes drivers and restraints of the Brazil Complementary and Alternative Medicine market along with the impact they have on the demand over the forecast period. Additionally, the report includes the study of opportunities available in the Brazil Complementary and Alternative Medicine market on a global level.

Download Sample of This Strategic Report:https://www.kennethresearch.com/sample-request-10172662

In order to give the users of this report a comprehensive view of the Brazil Complementary and Alternative Medicine market, we have included a competitive landscape and an analysis of Porters Five Forces model for the market. The study encompasses a market attractiveness analysis, wherein all the segments are bench marked based on their market size, growth rate, and general attractiveness.

The report provides company market share analysis to give a broader overview of the key players in the market. In addition, the report also covers key strategic developments of the market including acquisitions & mergers, new service & product launches, agreements, partnerships, collaborations & joint ventures, research & development, and regional expansion of major participants involved in the market on a global and regional basis.

The study provides a decisive view of the Brazil Complementary and Alternative Medicine market by segmenting the market based on type, age group, disease indications, distribution channel, and regions. All the segments have been analyzed based on present and future trends and the market is estimated from 2019 to 2027. The regional segmentation includes the current and forecast demand for North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.

A combination of various technologies will pave the way for the market growth in Brazil over the forecast timeline. Moreover, the occurrence of non-contagious ailments like heart disorders, high blood pressure, diabetes, and depression will propel the market growth during the period from 2019 to 2027. In addition to this, the complementary & alternative drugs approach for treating these non-communicable ailments will create lucrative growth avenues for the industry in other developing regions also. Apart from this, the integration of therapies like acupuncture and magnetic interventions will further boost the complementary and alternative medicine industry in Brazil.

Based on the type, the market for complementary and alternative medicine in Brazil is divided into Traditional Alternate Medicine Therapy, Diet and Herbal Based Therapy, Mind Therapy, Body Therapy, and Energy Healing Therapy. In terms of age group, the industry is classified into Infant, Adults, Adolescent, and the Elderly.

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On the basis of disease indications, the market is divided into Arthritis, Neurology, Cancer, Cardiology, Asthma, and Diabetes. In terms of distribution channel, the market is segmented into Direct Sales, Distance Correspondence, and E-Distribution.

Some of the key players in the market include Optum, Inc., Ach, Quantum-Touch, and Herboflora.

About Kenneth Research

Kenneth Research is a reselling agency providing market research solutions in different verticals such as Automotive and Transportation, Chemicals and Materials, Healthcare, Food & Beverage and Consumer Packaged Goods, Semiconductors, Electronics & ICT, Packaging, and Others. Our portfolio includes set of market research insights such as market sizing and market forecasting, market share analysis and key positioning of the players (manufacturers, deals and distributors, etc), understanding the competitive landscape and their business at a ground level and many more. Our research experts deliver the offerings efficiently and effectively within a stipulated time. The market study provided by Kenneth Research helps the Industry veterans/investors to think and to act wisely in their overall strategy formulation

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Brazil Complementary And Alternative Medicine Market Segments and Supply Demand Forecast 2020-2027 - Bulletin Line

#VisualAbstract: Treating latent tuberculosis infection with four months of rifampin versus nine months of isoniazid – 2 Minute Medicine

1. When compared to 9 months of isoniazid, 4 months of rifampin was a non-inferior alternative treatment of latent tuberculosis (TB) that was both cheaper and lead to lower healthcare usage amongst adult and pediatric patients in high-, middle-, and low-resource health systems in 9 nations.

2. Choosing rifampin represented a cost savings of 38% to the health system

Evidence Rating:1 (Excellent)

Study Rundown:Isoniazid, an inhibitor of mycobacteria cell wall synthesis, is the standard of treatment of latent TB. Rifampin, a more costly medication, is generally reserved for active TB treatment along with ethambutol and pyrazinamide. This study demonstrated that while rifampin is more expensive, its shorter treatment length and fewer adverse events resulted in a lower total cost across study sites. Ultimately this represented a cost savings to the health system of roughly one-third of the cost of isoniazid. The studys applicability was strengthened by its multi-centered approach that included representative countries across GDP. The failure to include individual cost burden limited the studys ability to fully account for possible barriers to treatment.

Click to read the study in Annals of Internal Medicine

In-Depth[randomized controlled trial]:This multicenter, prospective, open-label randomized controlled trial examined the cost of treatment for latent TB with isoniazid and rifampin across 9 diverse study countries (Australia, Benin, Brazil, Canada, Ghana, Guinea, and Indonesia). Participant eligibility was determined by documented skin test or QuantiFERON test, clinical risk factors, and clinician treatment recommendation. Baseline characteristics were attained from each participant including blood tests, chest radiography, and clinician medical assessment as were health data from routine follow ups with clinicians (which included attaining a complete blood count and liver function test). Six-thousand twelve adults and 829 children were included in the final modified intent-to-treat analysis with roughly half of the population originating from African countries. Seventy-one percent of adults and 82% of children completed treatment and 229 participants experienced an adverse event. The total cost of 9 of months of isoniazid was higher than 4 months of rifampin across all 9 study sites. Total cost was also higher in high-income countries when compared to middle-income or African countries. Cost components were heterogeneously distributed amongst the 3 income groups: routine follow-up visits made up 30 50% of total cost in high- and middle-income countries compared to roughly 15% of the cost in African countries. After multivariate analysis, the total average cost of rifampin was $340 (CI 95% $330 to $350) which represented a 38% savings for the health systems.

20202 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from2 Minute Medicine, Inc. Inquire about licensinghere. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

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#VisualAbstract: Treating latent tuberculosis infection with four months of rifampin versus nine months of isoniazid - 2 Minute Medicine

Letter: Reaping what you sow | Letters to the Editor – Arizona Daily Star

Re: the July 23 letter "Vote because your life depends on it."

The letter illustrates that some of the distrust of the medical profession that is hindering the fight against COVID-19 has been well-earned. Women with chronic debilitating symptoms are dismissed as psychiatric cases, while people of color cannot get treatment for pain. Research into the devastating epidemics of chronic fatigue syndrome, Lyme disease, and autism is underfunded in favor of research into expensive treatments for rare diseases. The CDC and Dr. Fauci's NIAID ignore evidence that Lyme bacteria can persist in the body and cause years of disability, fail to develop accurate tests for Lyme, and discredit labs that offer better tests.

This neglect drives many patients into alternative medicine, where some find healing and some learn distrust of Western science, including vaccines. Perhaps the public's maddening response to the pandemic will lead to a re-evaluation of medicine's practices and priorities.

Disclaimer: As submitted to the Arizona Daily Star.

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Letter: Reaping what you sow | Letters to the Editor - Arizona Daily Star

Thailand approves use of marijuana in local health promotion hospitals – The Thaiger

The blending of marijuana with other pharmaceutical products for the purpose of medical treatment is being given the go-ahead by the Thai government. Nation Thailand reports that the Ministry of Public Health has approved 17 formulations for use in local health promotion hospitals.

Sub-district Health Promoting Hospitals are hospitals that are operated by either the MOPH or Department of Local Administration and were initially called health stations. These hospitals only have primary care capabilities and often serve villages within districts. Almost all of these hospitals do not accept inpatients and usually have no doctor on duty for the entire time. Wikipedia

Dr. Marut Jirasrattasiri, from the Department of Traditional Thai Medicine and Alternative Medicine, says over 60,000 patients have expressed interest in being treated with medicinal marijuana, with the department approving the drug for use.

Currently, 4 hospitals are understood to be participating, 3 of which are in the north-east of the country. These are Khlong Muang Hospital in Nakhon Ratchasima province, Chiang Phin Hospital in the province of Udon Thani, Ban Na Yao Nuea Hospital in Sakon Nakhon province, and Ban Na Pak Khow hospital in the southern province of Phatthalung.

SOURCE: Nation Thailand

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Thailand approves use of marijuana in local health promotion hospitals - The Thaiger

Balloon-expandable covered stent reveals promise as endovascular alternative to surgery in treatment of arterial emergencies – Vascular News

This advertorial is sponsored by Bentley.

Maria Antonella Ruffino, a vascular interventional radiologist at Azienda Ospedaliera Universitaria Citt della Salute e della Scienza in Turin, Italy, tells Vascular News about her teams growing clinical experience with covered stents as a platform that offer a minimally invasive solution for arterial emergencies. Ruffino gives an insight into the advantages of covered stents in such cases, their potential limitations, and which ones may be a favourable option for emergency treatment.

Arterial emergencies, such as bleeding, pseudoaneurysm, dissection, or fistula are potentially life-threatening conditions. Spontaneous or iatrogenic arterial emergencies require prompt diagnosis and treatment. During the last few decades, the treatment of these lesions has shifted from emergency open surgery to an endovascular approach, and the latter is rapidly becoming part of the treatment algorithm.

What are the advantages of using covered stents in such emergency cases?

The main endovascular approaches include use of covered stents and embolisation. A key advantage of using a covered stent in an emergency case, when compared to embolisation, is that a stent graft guarantees the immediate exclusion of the lesion without the sacrifice of the target vessel, avoiding the risk of non-target embolisation, which can result in ischaemic complications and rebleeding. Preservation of flow is crucial particularly in districts with a terminal vascularisation, without collaterals, such as the limbs and kidneys. Additionally, this also applies to the liver, where it is uncertain whether extrahepatic arteries provide sufficient collateral circulation in case of hepatic artery occlusion.

What is your clinical experience with covered stents?

At our centre, we started using the BeGraft peripheral stent graft (Bentley, Hechingen, Germany) in June 2015. In the beginning, we used it for iliac procedures in elective cases of severe aortoiliac occlusive disease. Subsequently, we expanded this to include cases of rupture or dissection, and for severe complications that can present when long, calcified iliac occlusions are treated. The availability, wide sizing range, goodtrackability and conformability of these stent grafts and their low profile (6F compatible up to 8mm diameter) led us to extend their use to other vessels in case of arterial injuries. Since 2018, we have also used the BeGraft aortic stent graft, which has allowed us to treat vessels of larger diameters. Our cardiology colleagues already use the BeGraft coronary stent.

During the last few years, we have treated many emergency cases with the BeGraft stent graft family. These include iliac ruptures or renal pseudoaneurysms which are quite common but also more complex cases, like common carotid artery bleeding or penetrating aortic ulcer rupture.* In these last two scenarios, in particular, where we needed a large stent graft (12mm), we have experienced first-hand how a larger diameter BeGraft stent can perform in tortuous anatomies, thanks to its good trackability and low profile, as it can be used with small vascular sheaths (9F in these cases).

Part of our experience, which focused on iatrogenic arterial injuries, has been recently published in Medicine, reporting a technical success of 100% and a clinical success of 88%. No device- or procedure-related deaths, nor major complications were reported. There was no patency loss at mid-term follow-up (average FU 390 +/- 168 days).1

Are there any limitations associated with the use of covered stents for emergency cases?

Almost all arterial lesions can be treated with covered stents, except for those without anatomic suitability, such as very distal lesions, or those without an adequate proximal and distal neck. Similarly, arterial lesions that are located in vessels of a calibre not suitable for stenting cannot be treated with covered stents. Finally, in case of tortuous anatomy or at a joint, when possible, a self-expandable covered stent is the preferred option.

What are your must-have sizes of covered stents for emergencies?

Arterial emergencies can present with a variety of lesions that can be very different in aetiology and characteristics, and located in vessels that can vary significantly in size. This is why we require a wide array of differently sized stent grafts in order to select the most suitable one. It is, therefore, difficult to say which sizes are a must-have.

Our experience shows that, in the case of arterial injuries, the proper sizing of the stent graft is essential to achieve technical and clinical success, without complications and recurrences, which further highlights the importance of having a wide range of stent grafts on shelf to treat arterial emergencies, and the BeGraft family has the broadest covered stent platform in the market.

Overall, endovascular treatment with BeGraft covered stents, with preservation of distal flow, is minimally invasive, safe, and effective in the management of arterial injuries and emergencies. Furthermore, all the aforementioned device characteristics allow for the rapid treatment of the lesion, even in case of tortuous anatomy.

*The usage of the BeGraft aortic for treatment in the carotid artery or PAU is off label.

References

Case images

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Balloon-expandable covered stent reveals promise as endovascular alternative to surgery in treatment of arterial emergencies - Vascular News

PolyA-miner accurately assesses the effect of alternative polyadenylation on gene expression – Baylor College of Medicine News

Image courtesy of HK Yalamanchili/Liu lab/Nucleic Acids Research, 2020

Researchers with an interest in unraveling gene regulation in human health and disease are expanding their horizons by closely looking at alternative polyadenylation (APA), an under-charted mechanism that regulates gene expression.

APA is about modifying one of the ends, called the 3-prime end (3end), of RNA strands that are transcribed from DNA. The modification consists of changing the length of a tail of adenosines, one of the RNA building blocks, at the 3end before RNA is translated into proteins, said first author Dr. Hari Krishna Yalamanchili, a postdoctoral associate in the lab of Dr. Zhandong Liu at Baylor College of Medicine. This adenosine chain helps to determine how long the messenger RNA lasts in the cell, influencing how much protein is produced from it.

The interest in APA has resulted in the development of several 3 sequencing (3Seq) techniques that allow for precise identification on APA sites on RNA strands. But what researchers are missing is a robust computational tool that is specifically designed to analyze the wealth of 3Seq data that has been generated.

Until now, researchers have been using traditional RNA sequencing computational tools to analyze the 3Seq datasets. Although this approach produces results, it does not maximize the potential amount of information that can be extracted from that data, Yalamanchili said. Here we developed a computational tool that precisely analyzes 3Seq data. We call it PolyA-miner.

Yalamanchili and his colleagues used their new computational tool to analyze existing 3Seq datasets. PolyA-miner not only reproduced the analyses achieved with traditional computational tools, but also identified novel APA sites that were not detected with the other analytical approaches.

We were surprised when the PolyA-miner analysis of a glioblastoma cell line dataset identified more than twice the number of genes with APA changes than were initially reported, Yalamanchili said.

I think that the most exciting part of this new tool is that it enables us to precisely reflect gene-level 3 changes and to identify many more APA events than before. With other analytical approaches, we underestimate the effect and number of poly-adenylation events, said Liu, associate professor of pediatrics and neurology at Baylor and the Jan and Dan Duncan Neurological Research Institute at Texas Childrens Hospital.

This development has tremendous implications for basic research and for the potential translation of scientific findings into the clinic. APA is considered a major mechanism for RNA regulation that has strong relevance both in cancer and neurological diseases. PolyA-miner can assist scientists looking to identify the genetic causes of these diseases by determining whether there are differences in APA between diseased and normal cells. With this new analysis, scientists can take a fresh look at existing genomic datasets that may provide an answer to the cause of human conditions, as well as studying newly developed datasets.

Previously, people knew about APA changes, but did not consider them to be major contributors to gene regulation mainly because we lacked the computational tools to determine APAs overall influence on gene expression, Yalamanchili said.

PolyA-miner has shown that APA seems to play a larger role in gene regulation than we had previously thought.

Read the complete article in the journal Nucleic Acids Research.

Other contributors to this work include Callison E. Alcott, Ping Ji, Eric J. Wagner and Huda Y. Zoghbi. The authors are affiliated with one or more of the following institutions: Baylor College of Medicine; Jan and Dan Duncan Neurological Research Institute at Texas Childrens Hospital; University of Texas Medical Branch, Galveston; and Howard Hughes Medical Institute, Houston.

Financial support for this project was provided by Cancer Prevention Research Institute of Texas (RP170387), Houston endowment, Chao endowment, Huffington foundation, Howard Hughes Medical Institute, NRI Zoghbi Scholar Award, National Institute of Neurological Disorders and Stroke (F30NS095449), National Institute of General Medical Sciences [R01-GM134539) and the National Cancer Institute (R03-CA223893-01).

By Ana Mara Rodrguez, Ph.D

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PolyA-miner accurately assesses the effect of alternative polyadenylation on gene expression - Baylor College of Medicine News

11 ways to have more energy in the mornings – Medical News Today

Morning fatigue is normal for many people. While it is important to focus on underlying causes to ensure good quality sleep, there may be ways to energize the body and help someone feel more awake in the mornings.

In this article, we discuss tips that may help a person feel energetic in the morning or wake up quicker.

Someone who drinks water first thing in the morning helps provide their body with the hydration it needs to start the day. It can also ward off any sleepiness from mild dehydration. A common symptom of dehydration includes fatigue.

When a person drinks water, it stimulates other organs and systems in the body, and may encourage a more wakeful state.

Some people prefer a glass of warm water, or water with lemon and cinnamon, to further stimulate the body.

Someone who performs simple stretches helps warm up their muscles and promote circulation in the body, which could aid waking up in the morning. Many people stretch instinctively, such as moving their arms over their head, or extending their legs in bed.

A person who takes 5 minutes to stretch or perform some simple yoga poses may help awaken their muscles and body.

Exercise while tired may not sound appealing, but it can stimulate the body, get the blood flowing, and help make a person feel more alert. The workout does not have to be intense.

Simple activities, such as a short brisk walk, dancing to music, or even a few jumping jacks, can help get the heart and breathing rate up, which can wake the body up faster.

Breathing exercises can stimulate the body, as it raises oxygen within the circulation, which could make a person feel more awake.

Long, deep breaths, or guided breathing meditation techniques may help someone feel more awake and alert.

When someone wakes up to an abrupt alarm, the temptation to snooze for a few extra minutes may feel good, but it could make them feel more tired when they wake up again.

As they try to fall back asleep, they are unlikely to feel the benefits of rest, and may instead experience sleep inertia. This is the feeling of confusion and fatigue after waking up.

For many people, it may be better to immediately get out of bed and start their day when the alarm clock goes off.

If this is difficult, a person can try to keep the alarm out of reach from the bed. If they place the alarm across the room, they will be less likely to snooze, as they physically need to get out of bed and turn it off.

Cold showers in the morning may energize and invigorate. While warm showers tend to relax the body and mind, cold water may do the opposite.

A 2016 study suggests that an increased norepinephrine concentration occurs from having a cold shower.

A study in North American Journal of Medical Sciences notes that cold water causes the deeper tissue blood vessels to dilate, which increases heart rate, blood flow, and circulation. Therefore, cold showers may stimulate the body to wake up and be more alert, causing a person to feel energized.

If a person does not wish to have a cold shower, they can splash cold water on their face. This may produce a similar stimulating effect.

Some scents tend can quickly make a person feel awake or brighter, though effects vary from person to person.

Simple smells such as brewing coffee, fresh peppermint, or lemon zest may help energize someone almost instantly.

An animal study in Evidence-Based Complementary and Alternative Medicine suggests that some smells may help reduce fatigue, including essential oils of:

While the study focuses on sluggishness from exercise fatigue, the same oils may help invigorate someone in the morning.

While breakfast is important to energize the body, it may have the opposite effect if someone eats a large meal. People who consume a big breakfast may notice they feel more sluggish as the body digests their meal.

They may also rely on stimulants, such as caffeine, to give them energy.

Learn more about why people feel tired after eating.

A smaller and healthful breakfast may help people start their day quicker and sustain their energy levels. They could try porridge, cereals, eggs, fruits, and vegetables.

Learn more about the best foods to eat for energy.

Stimulants are a simple way to get an energy boost in the morning. Caffeinated drinks, such as coffee and tea, are popular breakfast choices because they are effective.

However, many people can experience a caffeine crash after a few hours, and energy levels may drop to even lower than before.

A study in Open Access Journals of Clinical Trials notes that while cognitive abilities can receive a boost with caffeine, these levels reduce around 5 hours afterward. This could encourage someone to consume higher quantities of caffeine to stay awake or alert.

This can also affect sleep for that evening, and result in more fatigue the next morning.

While it may seem difficult at first, a person who avoids stimulants in the morning may have more natural energy throughout the day.

A person who takes in sunlight after waking up, for example, during a morning walk, may feel more energized. This is because the short wavelength blue light found in sunlight stimulates the brain.

A study in the Journal of Biophotonics notes that this short wavelength light is important to suppress melatonin in the brain, which is a hormone that makes a person sleepy.

The best way to ensure someone gets energy in the morning is to ensure good sleeping habits. People who wake in the morning and feel tired may wish to look at their nighttime routines, and make changes to help them get better rest.

Some research suggests that more than a third of adults in the United States do not get enough regular sleep.

Some general sleep tips include:

There are several ways to help someone get more energy in the morning. While these tips will work for many people in the short term, it is important to create long-term habits that help them feel energized throughout their day.

A person can practice a combination of good sleep habits and morning routines to help them muster enough energy in the morning.

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11 ways to have more energy in the mornings - Medical News Today

Seven ways Swindon town centre could be improved by 25m bid for government cash – Swindon Advertiser

A 25 MILLION plan which would help transform the town centre has taken a step forward.

Seven projects have been identified by experts from the public, private and voluntary sector in Swindon as the council bids for a share of the 3.6 billion Towns Fund.

Should it succeed, it would spend the money on making land ready for new homes and offices at Kimmerfields, regenerating the David Murray John Tower, creating a Brunel Centre market hall, refurbishing the Health Hydro, fitting out space at the Carriage Works to support the digital economy and upgrading the streets around the Railway Village.

These have been selected from 20 projects suggested by a dozen different organisations in response to a call by the council for suitable schemes. Swindon is one of 101 places invited to make a bid.

Richard Newland, chairman of the Town Deal board and a director at Nationwide Building Society, said: The board has done a fantastic job of pulling this investment plan together at such short notice because we recognise the importance of being one of the first places in the UK to submit a bid to the government.

The Covid-19 pandemic has brought many economic challenges and this funding would be a huge boost to Swindon and help to stimulate further investment in the town, creating jobs and greater prosperity for the people who live here.

We believe we have a strong bid and we will be submitting the investment plan to the government shortly.

The draft Town Investment Plan will be submitted at the end of the week and a decision by government is expected by the end of the year.

Whitehall asked that funding proposals should drive long-term economic and productivity growth through town centre regeneration and investment in connectivity, land use, economic assets including cultural assets, skills and enterprise infrastructure.

A report to the Town Deal board, made up of councillors, business people and members of the community and voluntary sectors started with praise for Swindons many accomplishments.

It read: If you bank with Nationwide, use Intel products, travel by train, fly in an A330, drive a Mini or a Honda Civic, have ever visited a National Trust property, watched Tim Peakes progress through space, or have simply benefited from scientific or medical research, youve probably got Swindon to thank.

But the report adds that growth has largely happened on the edge of town and says the bid will try and rectify this.

It read: Swindon is among the most productive towns and cities in the country, but little of the wealth generated in Swindon is retained in the town or its borough. Where Swindon has grown, this has been concentrated on its outer edges.

This has diminished the town centres role as the cultural, commercial, and civic heart of the town. It is now characterised by a relatively poor post-war built environment, vacant retail units, and several conspicuous undeveloped brownfield sites.

The seven places the money would be spent:

Project 1: Kimmerfields Enabling Infrastructure (6m)

Bringing forward further residential and commercial development to the north of the Parade shopping centre between Corporation Street and Fleming Way, and adjacent to the bus station. The Kimmerfields site would be serviced with new utilities infrastructure, estate roads and landscaping, and public realm and green space.

Project 2: Heritage Action Zone streets and spaces (3m)

The upgrade of a major thoroughfare from Swindon Railway Station into the Great Western Historic Area. This will create greater links between existing centres of economic activity in Swindon. Upgrading this route will involve public realm improvements along Station Road, Sheppard St and London Road, and improvements to the tunnels at Sheppard Street and Bristol Street.

Project 3: Health Hydro refurbishment (5m)

A complete refurbishment of the Health Hydro, one of two key Grade II* listed heritage assets in Swindons Railway Village. Facilities include a 33m pool, gym, exercise rooms, Turkish Baths and alternative medicine practitioners, all within a historic setting.

Project 4: Carriage Works regeneration (5m)

Expanding on the regeneration of the Grade II listed Carriage Works building, which is being restored as a business incubation centre and office space.

Project 5: Create Studios at Carriage Works (0.4m)

Fit out one of the new units at the Carriage Works to create a landmark media production facility, including film and sound studios, teaching and workshop spaces, a cafe and more.

Project 6: David Murray John Tower regeneration (5.5m)

Regenerating the town centres most significant landmark building. The office accommodation is now considerably dated with no prospect of a commercial let. The residential element (floors 9 and above) have seen some modest investment in infrastructure over the years but the building, requires a significant refit.

Project 7: Brunel Centre Market Hall (0.1m)

Creating a modern, vibrant market hall which will create opportunity for deli counters, creative industries, and artisan producers to benefit from a modern market feel and fit within a well-designed building.The market will support growers and producers and make the best of local skills.

Continued here:

Seven ways Swindon town centre could be improved by 25m bid for government cash - Swindon Advertiser

What is hydrotherapy and how does it work? – The New Times

Although hydrotherapy is very effective in physiotherapy rehabilitation, Charles Munyambonera, a physical therapist in Kigali, says it is not used as much within.

He says that this form of treatment is very effective, especially for people with rheumatic ailments.

This is because when this form of treatment is used, such patients have chances to do their movement with less pain, and as they do so, their joints get the movements they might have lost before, he says.

The medic goes on to warn that this form of treatment should only be carried out by skilled personnel to avoid risks and repercussions.

He, however, encourages hospitals to include this form of treatment in the physiotherapy modalities.

At the moment, the only known health facility with skilled personnel that offers hydrotherapy treatment in the country is King Faisal Hospital.

Understanding hydrotherapy

Francis Habumugisha Goodrich, PhD Public health practitioner in Kigali, says hydrotherapy or water cure is a part of alternative medicine, occupational therapy, and physiotherapy that involves the use of water for pain relief and treatment.

He says that it involves the use of water to treat conditions, such as arthritis, rheumatic complaints and other ailments.

Although it bears a resemblance to swimming, he says it is different because it requires the individual to undertake various exercises in a warm pool of water.

The water temperature in the pool, he says, should approximately be 33 to 36C.

This water is much warmer than what you will encounter in a normal swimming pool. Hydrotherapy treatment is usually conducted in a hospitals physiotherapy department, he says.

Why its important

Munyambonera says hydrotherapy uses the principle known as Archimedes.

He explains that this is when you put something in the water; it tends to go vertically with animation of gravity.

The power to come up is equal to the water that is moving it. This scientific principle is the one helping in treating people, he says.

Munyambonera says when treating patients with limited range of motion, limited movements in the joints, they can easily do movements underwater than when they are not.

But again, he notes that when one wants to apply resistance, like going downwards from the upper part, it becomes hard.

Conditions where hydrotherapy is applicable

According to Munyambonera, hydrotherapy is good for people with pain, or those who feel pain when they are doing movements, and if they use water, the pain lessens.

It is also used with people who have rheumatic conditions like arthritis, polyarthritis, as this helps them do their movements with less pain.

This, he says, doesnt mean that the pain will go down to zero, but at least it wont be as intense.

Hydrotherapy is also used for people who had surgeries, such as post joint surgeries, as they tend to have pain after surgery.

For them to go back to the normal movements of their body and restore them, they start with less painful procedures that can be done underwater, he says.

Its also applicable in post hip surgeries this is where the joint of the hip has been replaced by a metal.

In such cases, he says they expect the patient to have limited movements in the hip.

Back surgeries and gout are also some of the conditions where hydrotherapy can be applicable.

Habumugisha says gouts complications can sometimes spread to other places, like the knees.

For such people, they hardly do their movements, have bent knees and because this condition is so painful, its not possible to bring back their range in the normal setting, therefore hydrotherapy becomes the only option, he says.

He adds that any movement they do actively or perceivably may lead to a lot of pain.

In such cases, he says what is normally done is to put them under hot water as the hot water tends to relax the muscles.

What you should know

Munyambonera says after the patients do active exercises themselves, the muscles and joints become relaxed.

Another important aspect, he says, is that patients, when under water, need to be helped to stretch and mobilise stiff joints.

He goes on to add that an expert can include resistance, like using heavy balls underwater.

The balls tend to help bring them back, push them into the water, and this becomes resistance, he says.

For instance, he mentions that in the case where a patient has a weak leg, they push them back downwards, where the water acts as resistance.

With pain, limited range of motion can be used in muscle weakness, and arthritis conditions.

Celestine Karangwa, a physiotherapist at TCM Technology Clinic in Remera, Kigali, says in medicine, a contraindication is a condition or factor that serves as a reason to withhold a certain medical treatment due to the harm that it would cause the patient.

Contraindication is the opposite of indication, which is a reason to use a certain treatment, he says.

Munyambonera says there are contradictions where hydrotherapy isnt inducted.

For instance, he says, if a person has a fresh and open wound, hydrotherapy is contraindicated because it may lead to infection.

Even though it has to be cleaned with disinfectants before and after use, even the patient might re-infect themselves from the skin to the wound, he cautions.

Also, when treating people with urinary incontinence, hydrotherapy is contraindicated as well.

He says that when they go in hydrotherapy, controlling the urine could be hard for them.

How long does treatment take?

Depending on the amount of pain, Habumugisha says with hydrotherapy, the time it takes for one to be completely healed varies.

For example, he points out that people with rheumatic pains cant be relieved in a day.

Therefore, he says, as they have more sessions, they get to feel better with time. He says that normally, one session can go for 30 minutes to an hour.

Munyambonera explains that this is because when people are doing exercises in hot water, generally, they get tired within a short time.

Some can do an hour or 40 minutes per session, so they always consider the patients condition.

Generally, he says, they consider 15 sessions as a starting point for many conditions, but those with paralysis might need many more sessions because of their condition.

editor@newtimesrwanda.com

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What is hydrotherapy and how does it work? - The New Times

Stromal Vascular Fraction Market is Expected to Grow at a CAGR of 4.5% During the Forecast Period 2019 to 2029 – Market Research Posts

Stromal vascular fraction is gaining significant importance in various fields, including internal medicine, orthopaedics, plastic and general surgery,and wound healing.

Ease of harvest, abundant availability, and stable phenotype are some factors increasing the demand for stromal vascular fraction. Also, stromal vascular fraction secretes several soluble factors with anti-inflammatory, immunomodulatory, and analgesic effects, which leads to an alternative treatment option for various diseases, significantly benefitting the growth of thestromal vascular fraction marketduring the forecast period.

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Company Profiles

Delivery of stromal vascular fraction by intra-articular injection has advantages over surgical implantation, such as less invasiveness, better patient compliance, and lower cost.

The global stromal vascular fraction market was valued atUS$ 76 Mnin 2018, and is expected to witness a CAGR of around4%over the forecast period (2019-2029).

Key Takeaways of Stromal Vascular Fraction Market Study

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Stromal vascular fraction has emerged as an efficient alternative in the field of regenerative medication. However, better-structured and significant clinical investigations need to be carried out to demonstrate and define the therapeutic potential of stromal vascular fraction,says a PMR analyst.

Stromal Vascular Fraction Manufacturers Focusing on Innovative Methods to Optimize Tissue Recovery

Consistent up-gradation and innovation in methods to recover adipose tissue-derived mesenchymal stem cells (ATD-MSCs) for autologous use in regenerative medication applications are expected to offer significant opportunities for the stromal vascular fraction market.

For instance, LipoCell from Tissyou, is furnished with a semipermeable film that separates fat tissues from squander components with the assistance of continuous irrigation. The dialysis of the tissue limits the pressure and trauma to the cell and extracellular matrix, evacuating the blood and oil deposits, which are pro-inflammatory.

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More Valuable Insights on Stromal vascular fraction Market

Persistence Market Research brings a comprehensive research report on the forecasted revenue growth at global, regional, and country levels, and provides an analysis of the latest industry trends in each of the segments from 2014 to 2029.

The global stromal vascular fraction market is segmented in detail to cover every aspect of the market and present a complete market intelligence approach to the reader.

The study provide compelling insights on the stromal vascular fraction market on basis of product (SVF isolation products, SVF aspirate purification products, and SVF transfer products), application (cosmetic applications, orthopedic applications, soft tissue applications, and others), and end user (hospitals, ambulatory surgical centers, stem cell laboratories, and others), across six major regions.

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Feminine Hygiene Product Market Feminine Hygiene Products Market Segmented By Sanitary Pads/Napkins, Tampons, Panty Liners, Menstrual Cups, and Feminine Hygiene Wash.For More Information

Persistence Market Research (PMR) is a third-platform research firm. Our research model is a unique collaboration of data analytics andmarket research methodologyto help businesses achieve optimal performance.

To support companies in overcoming complex business challenges, we follow a multi-disciplinary approach. At PMR, we unite various data streams from multi-dimensional sources. By deploying real-time data collection, big data, and customer experience analytics, we deliver business intelligence for organizations of all sizes.

Our client success stories feature a range of clients from Fortune 500 companies to fast-growing startups. PMRs collaborative environment is committed to building industry-specific solutions by transforming data from multiple streams into a strategic asset.

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Stromal Vascular Fraction Market is Expected to Grow at a CAGR of 4.5% During the Forecast Period 2019 to 2029 - Market Research Posts

Alternative Cancer Treatment Market Structure Analysis for the Period 2018 2026 – Owned

Alternative cancer treatment therapies are now a days are actively involved in limiting the growth of cancer. These therapies are also known as precision medicines. Recently alternative cancer treatment have gained increasing focus in the industry as these therapies forms that uses complementary and alternative methods or techniques to prevent, and treat cancer at an earlier stage. Alternative cancer treatment market comprises of acupuncture, aromatherapy, exercise, hypnosis, massage, meditation, music therapy, relaxation techniques, yoga and other alternative therapies. Alternative treatments may not assume an immediate part in curing the tumor, yet they may enable you to adapt to signs and indications caused by various diseases. Basic signs and side effects, for example, nervousness, weakness, vomiting and pain, and stress might be decreased by these natural elective medicines. There are numerous choices one could seek after in elective growth medications and a brainy consolidated approach is regularly the best. In any case, certain elements stay clear and predictable and those are the contributing tumor factors that any treatment should completely address: informational signaling interference fields (bioenergetic blockages), unresolved traumatic emotional conflicts, excess of toxins, inadequate drainage, and failure of nutrient delivery systems.

Alternative cancer treatment market is growing, this is attributed to increasing prevalence of various types of cancers such as lung cancer, breast cancer, colorectal cancer, prostate cancer, lymphoma, leukaemia, melanoma etc. Also increasing awareness regarding natural alternative and complementary therapies such as acupuncture and chiropractic therapy is expected to drive the market over the forecast period. Growing healthcare expenditure, and rising insurance coverage, aids in the revenue growth of alternative cancer treatment market. Top alternative cancer treatment include IPT insulin potentiation therapy, iscador aka mistletoe extracts, Gerson Therapy, Ukrain, biomagnetic therapy, biotherapeutic detoxification & drainage and others. However, less efficacy and impact of these alternative along with less coverage to cure the cancer is expected to hamper the growth of the alternative cancer treatment market over the forecast period. Individuals have started ensuing an all-natural plan and method that included vegetable juicing, probiotic foods, organic, plant-based foods, raw juices, natural and immune-boosting supplements. Other complementary methods include proteolytic enzyme therapy, budwig diet, vitamin c chelation, frankincense essential oil therapy, sunshine and vitamin D3, oxygen therapy and hyperbaric chambers, and others.

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The Alternative cancer treatment market is segment based on the therapy type, end user and application

Alternative cancer treatment market is segmented into following types:

By Therapy Type

By Disease Indication

By End User

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Alternative cancer treatment market revenue is expected to grow at a significant rate, over the forecast period. The market is anticipated to perform well in the near future due to increasing awareness regarding various cancer types and their treatment protocols. Also the alternative cancer treatment market is expected to expand globally due increasing prevalence of cancer and increasing preference of healthcare professionals to prescribe supplements for the patients. The natural and supplemented therapies for lung cancer is anticipated to grow with a fastest CAGR over the forecast period, attributed to increasing number of smokers globally. Increasing competition among drug manufacturers, increasing investment in R&D and increasing number of new alternative therapies and dietary supplements are the major factors estimated to drive the revenue growth of alternative cancer treatment market.

Depending on geographic region, the alternative cancer treatment market is segmented into five key regions: North America, Latin America, Europe, Asia Pacific (APAC) and Middle East & Africa (MEA).

North America is occupying the largest regional market share in the global alternative cancer treatment market owing to the presence of more number of market players, high patient awareness levels, increasing awareness about complementary therapies and marketing activities in the region. Asia Pacific is expected to grow at the fastest CAGR because of increasing prevalence of different types of cancers in the region, thus boosting the market growth of alternative cancer treatment market throughout the forecast period.

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Key players of alternative cancer treatment market includes Innovative Medicine, LLC, Esperity, Northwest Natural Health Clinic, and many more. The companies in alternative cancer treatment market are increasingly engaged in strategic partnerships, collaborations, mergers and acquisitions to capture a greater pie of market share as the market is in the nascent stage.

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Alternative Cancer Treatment Market Structure Analysis for the Period 2018 2026 - Owned

Complementary and Alternative Medicine Market Is Expected To Grow At A Fast Pace During Forecast 2020 To 2025 | Report Including COVID-19 Impact…

Global Complementary and Alternative Medicine Market 2020

The Complementary and Alternative Medicine Market 2020 report includes the market strategy, market orientation, expert opinion and knowledgeable information. The Complementary and Alternative Medicine Industry Report is an in-depth study analyzing the current state of the Complementary and Alternative Medicine Market. It provides a brief overview of the market focusing on definitions, classifications, product specifications, manufacturing processes, cost structures, market segmentation, end-use applications and industry chain analysis. The study on Complementary and Alternative Medicine Market provides analysis of market covering the industry trends, recent developments in the market and competitive landscape.

It takes into account the CAGR, value, volume, revenue, production, consumption, sales, manufacturing cost, prices, and other key factors related to the global Complementary and Alternative Medicine market. All findings and data on the global Complementary and Alternative Medicine market provided in the report are calculated, gathered, and verified using advanced and reliable primary and secondary research sources. The regional analysis offered in the report will help you to identify key opportunities of the global Complementary and Alternative Medicine market available in different regions and countries.

Some of The Companies Competing in The Complementary and Alternative Medicine Market are: Columbia Nutritional, Herb Pharm, Herbal Hills, Helio USA, Deepure Plus, Nordic Naturals, Pure encapsulations, Iyengar Yoga Institute, John Schumachers Unity Woods Yoga Center, Yoga Tree, The Healing Company, and Quantum Touch

The final report will add the analysis of the Impact of Covid-19 in this report Complementary and Alternative Medicine industry.

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The report scrutinizes different business approaches and frameworks that pave the way for success in businesses. The report used Porters five techniques for analyzing the Complementary and Alternative Medicine Market; it also offers the examination of the global market. To make the report more potent and easy to understand, it consists of info graphics and diagrams. Furthermore, it has different policies and improvement plans which are presented in summary. It analyzes the technical barriers, other issues, and cost-effectiveness affecting the market.

Global Complementary and Alternative Medicine Market Research Report 2020 carries in-depth case studies on the various countries which are involved in the Complementary and Alternative Medicine market. The report is segmented according to usage wherever applicable and the report offers all this information for all major countries and associations. It offers an analysis of the technical barriers, other issues, and cost-effectiveness affecting the market. Important contents analyzed and discussed in the report include market size, operation situation, and current & future development trends of the market, market segments, business development, and consumption tendencies. Moreover, the report includes the list of major companies/competitors and their competition data that helps the user to determine their current position in the market and take corrective measures to maintain or increase their share holds.

What questions does the Complementary and Alternative Medicine market report answer pertaining to the regional reach of the industry?

The report claims to split the regional scope of the Complementary and Alternative Medicine market into North America, Europe, Asia-Pacific, South America & Middle East and Africa. Which among these regions has been touted to amass the largest market share over the anticipated duration

How do the sales figures look at present how does the sales scenario look for the future?

Considering the present scenario, how much revenue will each region attain by the end of the forecast period?

How much is the market share that each of these regions has accumulated presently

How much is the growth rate that each topography will depict over the predicted timeline

A short overview of the Complementary and Alternative Medicine market scope:

Global market remuneration

Overall projected growth rate

Industry trends

Competitive scope

Product range

Application landscape

Supplier analysis

Marketing channel trends Now and later

Sales channel evaluation

Market Competition Trend

Market Concentration Rate

Reasons to Read this Report

This report provides pin-point analysis for changing competitive dynamics

It provides a forward looking perspective on different factors driving or restraining market growth

It provides a six-year forecast assessed on the basis of how the market is predicted to grow

It helps in understanding the key product segments and their future

It provides pin point analysis of changing competition dynamics and keeps you ahead of competitors

It helps in making informed business decisions by having complete insights of market and by making in-depth analysis of market segments

TABLE OF CONTENT:

Chapter 1: Complementary and Alternative Medicine Market Overview

Chapter 2: Global Economic Impact on Industry

Chapter 3: Complementary and Alternative Medicine Market Competition by Manufacturers

Chapter 4: Global Production, Revenue (Value) by Region

Chapter 5: Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6: Global Production, Revenue (Value), Price Trend by Type

Chapter 7: Global Market Analysis by Application

Chapter 8: Manufacturing Cost Analysis

Chapter 9: Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10: Marketing Strategy Analysis, Distributors/Traders

Chapter 11: Complementary and Alternative Medicine Market Effect Factors Analysis

Chapter 12: Global Complementary and Alternative Medicine Market Forecast to 2027

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Complementary and Alternative Medicine Market Is Expected To Grow At A Fast Pace During Forecast 2020 To 2025 | Report Including COVID-19 Impact...

With a Funded Internship, Griffin Marshall ’21 Seeks An Alternative Treatment for Aquaculture – Bowdoin News

Griffin Marshall, on a Zoom call.

While this summer he is working in a lab running experiments and bioassays, last summer he spent a lot of time in swamps.

That's because Prospective Research is searching for the next great medicine in dirt. "Dirt prospecting," Marshall calls it.

"My job last year was field work and dirt dilutions. I'd go out with waders and sterile vials, scoop up dirt, and go back to the lab," he said. After diluting the samples and putting them in an incubator, he would watch what grewsometimes blooms of rainbow-colored bacteria colonies.

Prospective Research's team is smalltwo founders, two interns, and a scientist with a background in drug development. Now that they've collected some promising bacteria strains, they're developing them in the lab to see whether they can effectively fight against bacterial, fungal, or parasiticpathogens in aquaculturespecies like shrimp, salmon, and oysters.

This summer, Marshall has a Scott and Anne Perper Internship Fund from Bowdoin to support his summer internship. The fund is one of 102 grants that Bowdoin Career Exploration and Development awarded to students this year to pursue unpaid summer internships.

Marshall is working in an emerging area of discovery: the development of antibiotic alternatives that can control the spread of disease in marine organisms. "The implications are massive," he said. "In aquaculture, density is the key. If you can increase density, you get more food. But the biggest hindrance is disease."

Antibiotics in aquacultureare problematic, mainly for the resistance that might build up to them, and countries have placed strict regulations on their use. So Prospective Research is looking for a bacteria that will act like a probiotic and outcompete pathogens in farmed fish or shellfish populations.

"It works the same way as in your gut," Marshall said. "It will decrease the overall density of the pathogenic species. Pathogens are always present, but they only become a problem when there are a lot of them."

Marshall spends his days in a small laboratory in Beverly, Massachusetts, experimenting with different ways to grow the bacteria colonies he's collected from the environment. The promising ones that can be successfully cultivated are tested with live marine species in a lab in Arizona.

As a biology major and environmentalstudies minor, Marshall said he's interested in the intersections of science and environmentalism. "This is a really cool spot, because we're looking at aquaculture, which gets at the ecology aspect, but it also has microbiology," he said.

Working in a commercial lab has also been exciting, he said. "It's been a valuable experience, because it feels like what I am doing is not just for the sake of learning but for the sake of building a business, and I'm building more connections in the science world."

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With a Funded Internship, Griffin Marshall '21 Seeks An Alternative Treatment for Aquaculture - Bowdoin News

RHOC: Shannon Beador and her three daughters have Coronavirus – Champagne and Shade

THE REAL HOUSEWIVES OF ORANGE COUNTY, Tamra Judge, Braunwyn Windham-Burke, Shannon Storms Beador, Gina Kirschenheiter, Emily Simpson (Photo by:Casey Durkin/Bravo)

While filming was shut down in many places for extended periods of time, The Real Housewives of Orange County was one of the first franchises to start back up again. Shannon Beador had the ladies over to her house, and just last week, Gina Kirschenheiter said the group was going on a trip together while quarantining.

But on Saturday, Shannon took to her Instagram to say that she and all three of her daughters, Sophie, Stella, andAdeline had all tested positive for the Coronavirus. Ginas post about the RHOC trip was only ten days ago, so it isnt clear when exactly Shannon got sick but hopefully, no one else in the group contracted the virus. It was speculated that Shannon and Emily Simpson opted out of going on the trip toLake Arrowhead.

Shannon said that she and the girls are all staying in the same house, but in separate rooms. She also thanked those medical professionals who helped them.

Braunwyn Windham-Burke left some hearts in the comments, and her mother, Dr. Deb, offered to bring them food if needed. The comments were mostly positive, besides some others that criticized Shannon and the other ladies for being reckless.

Shannon has always been a bit obsessed with health, including her alternative medicine doctor, Dr. Moon. Dr. Moon and his energy medicine center were frequently featured on the show in Shannons earlier seasons.

Meanwhile, Kelly Dodd said that the coronavirus was Gods way of thinning the herd.I wonder how Shannon feels about those comments now?

This season of RHOCis certainly going to be different, and inevitably choppy with the timeline of things. Perhaps Bravo will acknowledge the virus and show how the ladies spent their time in quarantine. Or, perhaps, theyll just ignore it altogether. Only time will tell!

Get well soon, Shannon, Sophia, Stella, andAdeline!

For more information about COVID-19, visittheCDCs websiteor the website for your states Department of Health.

The Real Housewives of Orange Countywill be back later this year.

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RHOC: Shannon Beador and her three daughters have Coronavirus - Champagne and Shade

Is this the end of Turkish secularism? – Al-Monitor

Jul 24, 2020

The Hagia Sophia opened for Muslim prayer on July 24. As the world grapples with Turkish President Recep Tayyip Erdogans abrupt decision, many opposition figures have fallen in line to congratulate the decision.

One can understand the enthusiasm of the Islamist Felicity Party or Erdogans coalition partner Nationalist Movement Party, whose bases share strong feelings about the museum turning into a mosque. However, other parties reactions are more surprising.

Recent polls indicate only 20% of Good Party voters and 21.8% of left-leaning Republican Peoples Party (CHP) voters approve of the decision, along with 33% of the voter base of the pro-Kurdish Peoples Democratic Partys (HDP). The HDPs elected officials are the only ones who dared speak words of caution as the ruling Justice and Development Party (AKP) promotes a monolithic expression of identity.

Muharrem Ince, a 2018 CHP presidential candidate, announced he would join the first Friday prayers if he is invited.

Timur Kuran, a professor of economics and political science at Duke University, told Al-Monitor, We are observing rising preference falsification in Turkey on a host of matters. The reactions to Hagia Sophia offer a salient example. The opposition has applauded the decision not because it approves it. Rather, it is afraid to be labeled as anti-Muslim and to be tied to Kemalisms assertive secularism.

A few intellectuals have voiced criticism of the decision, to harsh treatment by pro-government media outlets.

One of the most striking comments came from author Orhan Pamuk, a Nobel laureate. Pamuk said, There are millions of secular Turks like me who are crying against this but their voices are not heard.

Political Islam has produced several red lines that no political figure dares to cross. The fear of offending Muslim sensitivities has crippled the opposition while giving free rein for Erdogan, who gleefully grabs more power. This timidity has led to serious policy consequences in the last two decades.

For example, the Turkish government has invested unreported sums of money into alternative medicine against the advice of the medical establishment. Traditional cures are touted as having been used and recommended by the Prophet Muhammad.

Another example is womens rights, the first and worst victim of political Islam. After seeking the right to wear their headscarves in the public domain, women are being gradually pushed back into the house. Femicide has skyrocketed, while womens presence in education, workspaces and parliament has declined.

A recent International Social Survey Program poll documented a spike in the number of those who support Sharia law. The figures, which stood at 14-19% 2009, increased to 27-32% in 2019.

Diyanet, Turkeys official religious body, has an exponentially growing budget and number of personnel have become beacons of political Islam. Religious sects have gained sufficient power within the state, many argue, to form a parallel state that led to a coup attempt in 2016. While the Fethullah Gulen movement was only one of them, the others mounting reach is an open secret in Turkey.

Law professor emeritus Levent Koker told Al-Monitor, Over time the AKP became entrenched as the political instrument of the Turkish nationalist establishment, now politically using religion more efficiently and visibly, turning the Diyanet into an overt instrument of political hegemony. This does not mean that the AKP, as an Islamist party, is changing the foundational characteristics of the Turkish Republic to turn it into an Islamic polity. To the contrary, what seems to be happening now is the rise of authoritarian rule with a strong reference to religion in a historical-political context in which Islam has been institutionalized as a mechanism of state control over society. It is an open-ended question whether this authoritarian formation could be reversed or will advance to turn Turkey into a Sharia-based state. The historical background says the latter option is very remote, while the former is possible but very difficult under the current national and international climate dominated by nationalist/populist authoritarians.

Birol Baskan, a non-resident scholar at the Middle East Institute, told Al-Monitor, For now, political Islam has fallen short of legislating on matters of everyday life, but has been quite successful reaching in its main goal. For years now, discussions with titles such as Islam and democracy, Islamic economy, Islam and ecology, Islam and women and others have been based on the assumption that Islam is relevant and involved in all areas.

Baskan observed that the opposition was a tacit or open accomplice in this process. He pointed out that many mayors and CHP officials have avoided using the term corruption and instead speak of economic waste a concept with stronger resonance in the conservative circles. All these are evidence of the success of political Islam, not its demise, he added.

Aykan Erdemir, senior director of the Turkey Program at the Foundation for Defense of Democracies and a former member of the Turkish Parliament, told Al-Monitor, A majority of Turkeys pro-secular figures have unknowingly internalized the Sunni hegemonic worldview and cannot imagine a future without the Turkish states direct control over the religious domain through the Directorate of Religious Affairs.

On Al-Quds Day, the speeches by the left-leaning CHP leadership and right-wing politicians were almost identical. One of the crucial consequences of this skewed understanding of secularism, Erdemir said, is that it has made the opposition apathetic to the persecution of and discrimination against Turkeys religious minorities." He went on, "We now witness that even a tame and timid version of secularism is no longer welcome in Turkey as an emboldened Erdogan pushes a more assertive sectarian agenda.

Kuran said secularism is not dead, however. It has gone underground, where it is expanding but also metamorphosing. When it reemerges, it will probably be a more tolerant variety. What emerges will probably be a form of passive secularism rather than the assertive secularism of the 1930s and 1940s, he explained.

With limited political accountability and a struggling economy, Turkish politics is becoming increasingly volatile. Secularism is on life support and those who do not fit into the ideal Sunni Muslim mold are quietly paying the price.

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Is this the end of Turkish secularism? - Al-Monitor

Chipping Away at the Surface of Melanoma Treatment: Narrowing Down Therapies – Targeted Oncology

With many systemic therapy options available for the treatment of patients with melanoma, the American Society of Clinical Oncology (ASCO) gathered together an expert panel to create guideline recommendations for choosing the optimal agent at multiple stages of the disease (FIGURE).1 They covered 1 systematic review, 1 meta-analysis, and 34 randomized trials to compile the new set of recommendations for treating patients with various stages of melanoma.1

When asked how treatment options have changed in the last 5 years, Rahul Seth, DO, lead author of the guideline, said, Melanoma is a field that has undergone a revolution in terms of treatment options and treatment outcomes. With so many therapies available and new ones being tested every day, deciding on a treatment regimen can be difficult.

Targeted Therapies in Oncology asked Seth, an assistant professor of medicine at State University of New York Upstate Medical University in Syracuse, if there were any therapy regimens not listed in the expert recommendations that he felt had merit. The short answer is no, the ASCO guideline [was] pretty exhaustive in all aspects, he said.

The guideline addresses 4 clinical questions regarding approaches to systemic treatment for different types and stages of melanoma, in addition to summarizing the trials on which the recommendations were based.

The evidence supporting the panels advice regarding systemic therapy in patients with melanoma who are ineligible for surgical resection was primarily based on a 2018 Cochrane Review, which included data from 122 randomized clinical trials through October 2017.1,2

The guideline indicates that patients with BRAF wild-type unresectable/metastatic cutaneous melanoma should be offered, in no significant order, combination ipilimumab plus nivolumab followed by nivolumab, single-agent nivolumab, or single-agent pembrolizumab.

Historically, patients in this population received chemotherapy with or without interferon and/or interleukin-2 (IL-2), but therapy success was limited and toxicity incidence was high. When introduced, the CTLA-4 inhibitor ipilimumab induced better progression-free survival (PFS) but also greater toxicity. Phase 3 results from trials comparing experimental regimens of ipilimumab (Yervoy) versus nivolumab (Opdivo; CheckMate 067, NCT01844505) or pembrolizumab (Keytruda; KEYNOTE-006, NCT01866319) showed significantly improved overall survival (OS) compared with the control arm of single-agent ipilimumab in both cases.

For patients with BRAF V600 unresectable/ metastatic cutaneous melanoma, the panel said the above regimens can be considered, in addition to BRAF/MEK inhibitor combinations of dabrafenib (Tafinlar) plus trametinib (Mekinist), encorafenib (Braftovi) plus binimetinib (Mektovi), or vemurafenib (Zelboraf) plus cobimetinib (Cotellic).

I do believe that gene mapping is necessary for patients, for there are possibilities to get targeted therapies which may benefit patients, Seth said. Efficacy can be increased, and we do recommend FoundationOne [CDx] testing if one has no options left.

Each BRAF/MEK inhibitor combination may produce different toxicity profiles; therefore, switching between regimens may be beneficial for patients experiencing unmanageable toxicities. However, there are no data regarding the effects on efficacy of such a switch.

When compared with chemotherapy, single-agent BRAF and MEK inhibitors have produced superior OS and PFS in randomized clinical trials. But when both types of agent are combined, OS and PFS are superior to those with BRAF inhibitors alone. Phase 3 trials with results supporting these recommendations include the CoBRIM trial (NCT01689519) of vemurafenib and cobimetinib, the COM-BI-v trial (NCT01597908) of dabrafenib and trametinib, and the COLUMBUS trial (NCT01909453) of encorafenib and binime-tinib, all with a control arm of single-agent vemurafenib. At this time, no head-to-head data are available to inform clinicians as to the best combination therapy.

Treating patients and handling their expectations and understanding of possible adverse effects is a huge part of practice, Seth said. I have found with more patient education [there are] better outcomes and a better quality of life.

Recommendations for second-line treatment depend on the patients BRAF biomarker status and type of first-line agent. Patients with BRAF wild-type tumors who progressed on PD-1 inhibitors may receive ipilimumab or ipilimumab- based therapy; those with injectable lesions are eligible for talimogene laherparepvec (T-VEC) therapy. Evidence for second-line ipilimumab is based on a single previous trial that investigated this agent following IL-2 or chemotherapy. However, because that studys first-line treatment was not a PD-1 inhibitor, the panel questioned its relevance and only weakly recommended this option.

Second-line recommendations for patients with BRAF V600 mutations include the BRAF/MEK inhibitor combinations discussed above following frontline PD-1 inhibition; conversely, PD-1 inhibitors may be considered following frontline BRAF/MEK inhibition. For either group, ipilimumab or ipilimumab-containing regimens are a suggested alternative.

Second-line therapies are chosen based on factors [related to] how the patient is doing with the current treatment, Seth said. There [are] no absolute criteria, but the clinicians decide based on the treatment options [that are out there].

Patients who are ineligible or unwilling to receive systemic therapy or participate in clinical trials may be given T-VEC as an alternative primary therapy. Evidence from the phase 3 OPTiM trial (NCT00769704) demonstrated mixed results for T-VEC versus granulocyte macrophage colony-stimulating factor, with a significant improvement in median time to treatment failure (HR, 0.42; 95% CI, 0.32-0.54) but not in OS (HR, 0.79; 95% CI, 0.62-1.00). Additionally, grade 3/4 toxicity was somewhat increased in the T-VEC arm.

The most recent FDA approval for a systemic melanoma treatment occurred in 2019, when the agency designated the PD-1 inhibitor pembrolizumab as an acceptable adjuvant treatment for patients with melanoma with lymph node involvement following complete resection.3

The panel investigated different adjuvant systemic therapy options, alone or in combination, to determine the best options for use in adults with resected stage II to IV cutaneous melanoma.

Nineteen randomized trials were reviewed in this section of the guideline, most of which were found to have a low risk of bias. The panel primarily examined the recurrence-free survival (RFS) and OS rates. Recommendation 2.1 advises against adjuvant nivolumab, pembrolizumab, or combination therapy with dabrafenib and trametinib for patients with stage II disease due to the lack of positive trial data. The panel suggested that patients seek to enroll in a clinical trial instead.1

However, the panel determined that for patients with resected stage IIIA to IIID disease and BRAF wild-type tumors, a year of systemic therapy with a PD-1 inhibitor, either nivolumab or pembrolizumab should be offered. The recommendations advised against the routine use of interferon and ipilimumab in adjuvant therapy. Patients with BRAF V600E/Kmutant disease may consider the same therapies in addition to the targeted BRAF/MEK inhibitor combination of dabrafenib plus trametinib.1

It was determined that patients with resected stage III disease with minimal lymph node involvement have a lower risk of relapse, thereby making individualized therapy after shared decision-making talks with the patient preferred over a broad recommendation.1

The phase 3 CheckMate 238 trial (NCT02388906) in patients with stage IIIB/C or IV melanoma found nivolumab superior to ipilimumab in terms of RFS (HR, 0.65; 97.56% CI, 0.51-0.83; P <.001) and toxicity. A similar RFS advantage was seen with the use of pembrolizumab versus placebo in patients with high-risk stage III melanoma (HR, 0.57; 98.4% CI, 0.43-0.74; P <.001) in the phase 3 KEYNOTE-054 trial (NCT02362594).1

With no head-to-head studies available to compare nivolumab and pembrolizumab, the panel determined that either treatment plan would be an acceptable option for these patients.

Efficacy of the combination of dabrafenib and trametinib was explored in the phase 3 COMBI-AD trial (NCT01682083) in patients with high-risk BRAF V600E/Kpositive melanoma following surgical resection. With a minimum follow-up of 3 years, the targeted therapy regimen had significant improvements in RFS (HR, 0.47; 95% CI, 0.39-0.58; P <.001) and OS (HR, 0.57; 95% CI, 0.42-0.79; P = .0006) versus placebo.

Randomized data testing the efficacy of interferon showed a significant benefit compared with observation. However, this was outweighed by the greater benefits demonstrated with more recently available agents coupled with the known toxicity of interferon, which led the expert panel to determine that interferon could not be recommended.

In the phase 3 ECOG-E1609 trial of ipilimumab at doses of 3 mg/kg and 10 mg/kg (NCT01274338), the CTLA-4 inhibitor had similar efficacy to interferon in terms of RFS and only showed improvement in OS at the lower dose (HR, 0.78; 95.6% CI, 0.61-1.00; P = .044). This result, coupled with data showing the superiority of nivolumab over ipilimumab, led the panel to determine that ipilimumab can no longer be recommended as a preferred agent.

For patients who have resected stage IV melanoma, the panel formed a consensus regarding single-agent nivolumab as the preferred agent based on evidence from CheckMate 238. The panel determined that pembrolizumab may be offered as an alternative to nivolumab, despite an absence of clinical data, based on similar efficacy of the 2 PD-1 inhibitors seen in key clinical trials. Dabrafenib plus trametinib may also be offered to patients with BRAF V600E/K mutations, particularly those who cannot receive or who cannot tolerate nivolumab.

Because noncutaneous forms of melanoma such as mucosal and uveal melanomaare less common than cutaneous forms, trial-based evidence is difficult to obtain due to small sample sizes. However, the panel did address a few specific studies in making recommendations for treating these patients.

Several clinical trials included subgroups of patients with mucosal melanoma but had insuff icient numbers of patients for the panel to draw conclusions. One phase 2 trial of patients with mucosal melanoma found improved RFS and OS with temozolomide plus cisplatin chemotherapy versus interferon and observation, with similar grade 3/4 toxicities between the 2 nonobservation arms. However, the panel considered those results as artifactual given the small sample size; therefore, it recommended that patients with mucosal melanoma follow the guidance given for unresectable cutaneous melanoma.

In uveal melanoma, selumetinib (Koselugo) compared with either temozolomide or dacarbazine demonstrated an improvement in PFS that was statistically significant (HR, 0.46; 95% CI, 0.30-0.71) but not clinically meaningful, and there was no difference in OS. The follow-up phase 3 SUMIT trial (NCT01974752) failed to produce improvement in either OS or PFS with selumetinib plus dacarbazine versus dacarbazine alone.

Uveal melanoma is commonly included in the exclusion criteria for studies of new therapies, making it difficult to find useful data to make treatment recommendations. The panel concluded that no specific recommendation could be made regarding patients with uveal melanoma and indicated that patients should be referred to clinical trials when possible.

No specific recommendation could be made for or against neoadjuvant therapy for resectable cutaneous melanoma. Current evidence suggests that the best option for these patients is referral to a clinical trial.

In forming this conclusion, the expert panel reviewed 4 trials. Two small trials led by Rodabe N. Amaria, MD, were terminated early and failed to produce results sufficient for drawing a conclusion regarding efficacy. The first trial (NCT02231775), which looked at neoadjuvant and adjuvant dabrafenib plus trametinib versus contemporary standard of care in 21 patients, was stopped early due to significant event-free survival improvement in the experimental arm (HR, 0.016; 95% CI, 0.00012-0.1; P <.0001). The second trial (NCT02519322) consisted of 23 patients treated with neoadjuvant ipilimumab and nivolumab versus single-agent nivolumab, both followed by adjuvant nivolumab. This trial was stopped early because patients had high toxicity rates and early disease progression.

Two other trials of different combinations of nivolumab and ipilimumab as neoadjuvant therapy failed to demonstrate a clear benefit at dose levels that did not lead to a significant increase in toxicity.

The panel concluded that potential benefit with neoadjuvant therapy may exist, and clinical trials are the best option for these patients.

There are many studies open, Seth said. I think studies looking at the BRAF[/MEK] combinations and immunotherapy will be the ones to help us in the future.

When asked about his current treatment preferences, Seth said, in the time of COVID-19 [coronavirus disease 2019], I am using immunotherapies for patients [who] are unable to get surgery.

I truly believe melanoma will become a treatable [disease], Seth concluded. The next 5 years are unknown, but we are bound to be better and more efficient in treatment.

References:

1. Seth R, Messersmith H, Kaur V, et al. Systemic therapy for melanoma: ASCO guideline. J Clin Oncol. Published online March 31, 2020.doi:10.1200/JCO.20.00198

2. Pasquali S, Hadjinicolaou AV, Chiarion Sileni V, Rossi CR, Mocellin S. Systemic treatments for metastatic cutaneous melanoma. Cochrane Database Syst Rev. 2018;2(2):CD011123. doi:10.1002/14651858. CD011123.pub2

3. FDA approves pembrolizumab for adjuvant treatment of melanoma. FDA. Updated March 18, 2019. Accessed May 22, 2020. bit.ly/3btFOiG

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Chipping Away at the Surface of Melanoma Treatment: Narrowing Down Therapies - Targeted Oncology

The real face of Reading’s Christopher Columbus statue was a pioneer of a different sort – Reading Eagle

When Monica Krick and her brother, Butch Parenti, look at the Christopher Columbus statue in City Park, they see the face and figure of their father's friend, Dr. Jesse Mercer Gehman.

The statue has generated protests in the racial justice period that followed the death of George Floyd in police custody in late May in Minneapolis. The protests expanded beyond the Floyd death.

Dr. Jesse Gehman, a native of Elverson, Chester County, grew up in Reading and was a pioneer in the field of natural health. Gehman was the model used in sculpting the Christopher Columbus statue in Reading's City Park.

Gehman, who grew up in Reading, was the model for the statue, sculpted in 1925 by Vincenzo Miserendino.

Whenever we went by the park, my dad would point out the statue and say Jesse posed for that, said Krick of Blandon.

She and Parenti of Reading credit Gehman, a pioneer in the fields of alternative medicine and naturopathy, for their father's longevity.

Their father, Nick, the well-known owner of the Keystone Meat Market at 857 Penn St., was91 when he died in 2008.

The elder Parenti, a lifelong disciple of Gehman, largely followed the naturopaths protocols for more than 70 years.

My dad listened to Jesse and was a good pupil, Krick said.

She remembers when her father developed a cyst that grew into his middle ear and bulged beneath his jaw.

Nicky, you have been a bad boy, she recalled Gehman said when consulted.

He blamed the growth on lapses in Nick's healthy diet and ordered a strict regimen of raw vegetables and fruits. After several weeks, the cyst drained and healed, she said.

Jesse had pretty much a cure for everything, Krick said. He advocated daily exercise and a vegetarian diet.

The naturopath favored eating a diet low in starchy and fatty foods, limiting consumption of meats, alcohol and caffeine and getting plenty of daily sunshine, fresh air and exercise. Outspokenly against smoking, he penned Smoke Across America, a treatise on the dangers of tobacco use, in 1943.

He also drew criticism from the established medical community due to what were seen as his unscientific methods and his anti-vaccination stance.

"Jesse could look at someone and diagnose their health problems," Krick said, noting the doctor could detect potential diseases and health conditions by examining a patient's eyes, skin and fingernails.

Dr. Jesse Gehman, a native of Elverson, Chester County, grew up in Reading and was a pioneer in the field of natural health. Gehman was the model used in sculpting the Christopher Columbus statue in Reading's City Park.

Gehman's interest in the health and strength-training movement, then known as physical culture, began during his teen years.

Typical exercise routines used by the movement often included the use of wooden clubs, dumbbells and medicine balls, equipment popular in the gymnasiums of Olivet Boys Club and Reading YMCA, where Gehman worked out.

After attending preparatory school in Massachusetts, he enrolled in the American College of Naturopathy and Chiropractic, graduating in 1925 with degrees in nutrition, naturopathy and chiropractic medicine.

The chiropractic school was established in New York in 1901, the same year Gehman was born.

He went on to complete a doctorate in natural philosophy in 1931.

Jesse Mercer Gehman poses as artist Vincenzo Miserendino puts the finishing touches on the wax sculpture to be used in casting the bronze figure of Christopher Columbus in Reading City Park.

While in his early 20s, Gehman settled outside New York, where he worked as a model, sometimes posing for Miserendino, according to an article in theReading Times, May 12, 1925. He also boxed and wrestled professionally under the name Jim Mercer.

His much younger brother, Marvin K. Gehman, later wrestled as Atomic Marvin Mercer. A World Junior Heavyweight wrestling champion, Marvin won 1,887 of his 2,327 professional matches with 368 others ending in a draw, according to the Reading Eagle, June 28, 1992.

The younger Gehman excelled in sports, particularly swimming during his years at Reading High School in the 1930s, and in the 1940s wrestled in matches at the Reading Armory.

About that time, he met the slightly younger Parenti, also a practitioner of physical culture and a wrestler. Marvin introduced Nick to Jesse, leading to a lifelong friendship, Krick said.

Krick, Parenti and their sister, Sandra Sikora, sometimes accompanied their father and stepmother their mother died in 1965 on visits to Gehman, his wife, Agnes, and their children. The Gehmans had moved to a farm inDuncannon, Perry County, where they founded a health spa and natural healing center,called the Natural Living Foundation.

Gehman served as president of the American Naturopathic Association and was in demand as a lecturer at the meetings of natural health organizations. He was honored in October 1975, by the International Vegetarian Union for his efforts in advancing vegetarianism.

Gehman died at age 75 the following year.

In addition to his second wife, Agnes Stone Gehman, he was survived by their two adult children and three children from his first marriage, according to his obituary in The News of Paterson, N.J.

Krick said she kept in touch with Gehman's family for many years and still follows many of the doctor's precepts, which she calls "Jesse-isms."

"He recognized the benefits of a healthy diet and exercise," Parenti said. He really was ahead of his time."

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The real face of Reading's Christopher Columbus statue was a pioneer of a different sort - Reading Eagle

NSW shoppers told to wear face masks to fight COVID – Tweed Daily News

Masks are set to become the next new norm as supermarkets and shops start requiring customers to cover their faces.

Woolworths is "strongly encouraging" shoppers in Fairfield and Liverpool to wear masks in its stores, including supermarkets, BWS, Dan Murphy's and Big W.

Shane Warne, wearing a personalised SW mask, cops a parking ticket in Melbourne this week. Picture: Media Mode

The NSW government has not yet mandated masks, but Health Minister Brad Hazzard said they "worked well for The Masked Crusader, Zorro, and today can work well for us - particularly when it is part of our armoury to beat COVID-19.

"In addition to social isolating, our armoury includes constant cleaning of hands, getting tested and staying home if you have any flu-like symptoms.

"If we do all that we should be as effective as the Masked Crusader."

Apple stores already require all customers wear masks.

In a letter to Woolworths Reward customers, the chain's chief executive Brad Banducci hinted more stores could follow, explaining the outbreak in Victoria "and to a lesser extent NSW" was "an unfortunate reminder that we continue to live with COVID.

"Face masks are increasingly becoming part of everyday life. If toilet paper was the symbol of the first phase of COVID, then masks are symbolic of this phase," he wrote.

"With face masks fast becoming part of everyday life in Victoria (and indeed in many parts of Europe and the United States), it feels prudent to prepare for the same in NSW."

Shop, Distributive and Allied Employees' Association secretary Bernie Smith said the union was urging employers to offer staff masks and training.

"Employers need to have masks for staff and staff are encouraged to wear them," he said. "And they need to have sufficient masks to be able to be changed during a shift."

Coles has asked shoppers to wash or sanitise their hands before entering stores, use contactless payment whenever possible, avoid touching faces - masked or not - and cough or sneeze into a tissue or elbow.

Susan Duffy and her granddaughters Imogen (left) and Alexis Schroder wore their masks while shopping at Liverpool Woolworths on Saturday. Picture: Sam Ruttyn

Among those wearing masks while out shopping at their local Woolworths store in Liverpool yesterday were nurse Susan Duffy and her grandchildren Alexis and Imogen Schroder.

Ms Duffy said she was disappointed by the number of shoppers without masks.

"Too many people seem to have forgotten we're still in a pandemic because it has been dragging on for so long they've become complacent," she said.

Ms Duffy was among the estimated one in 20 Westfield Liverpool shoppers wearing masks yesterday.

Police and Emergency Services Minister David Elliott yesterday warned that residents at evacuation centres during the looming storms would need masks.

Sporting superstars are obviously able to get their hands on personalised face masks.

Former cricketer Shane Warnes mask has his initials and the number 23 on it. Picture: Media Mode

Wearing a fancy black mask with an SW logo to shield him from the dangers of COVID-19, former spin king Shane Warne wasn't going to be fined for breaching the latest health regulations in Melbourne yesterday.

Pity he didn't apply the same diligence to his parking arrangements.

After a lengthy visit to an alternative medical practice, he returned to his vehicle to find a dreaded white ticket flapping under the wipers of the luxury matt black Mercedes SUV.

Warne had spent almost two hours at a traditional Chinese medicine centre in Melbourne - possibly tending to some niggling injuries from his years as the world's best spin bowler, or maybe a case of RSI in those texting fingers.

His black mask has his initials in big bold lettering together with '23' - the number he wore on his back during the 145 Tests and 194 One Day Internationals he played for Australia.

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NSW shoppers told to wear face masks to fight COVID - Tweed Daily News

Queen’s team work on link between bacterial co-infections and Covid-19 – Belfast Live

A half a million pound grant has been awarded to scientists in Northern Ireland to find alternative treatments for Covid-19 and investigate the bacterial infections that targeted the sickest patients.

The research project will be run at Queens University by Professor Jos Bengoechea.

Available information already shows that bacterial co-infections are associated with severe cases of Covid-19 in more than half of the patients tested.

And those infections appear to have a limited arsenal of antibiotic drugs to combat them.

Using the clinical data and postmortem analysis of tissues from Covid-19 patients, scientists have a battle ahead to work out the interactions between the SARS-CoV-2 virus and bacterial infections.

They believe a patient presenting with bacterial infection alongside the virus may face a more difficult the clinical outcome and severity of Covid-19, which combined may increase the risk of death.

The experts believe it is possible that the virus and bacteria may affect each others virulence by interfering with protective defense responses within the body.

And co-presence of bacteria and the virus may increase the damage of the lungs and facilitate the virus movement into the brain and the gut.

Now that the research team from Queens University Belfast has been awarded the 500,000 UK Research and Innovation (UKRI) Rapid Response Fund grant, they will to investigate the role of bacterial co-infections in Covid-19, and drug repurposing for the treatment of the disease.

The grant is one of only five projects supported in the UK by the Biotechnology and Biological Sciences Research Council (BBRSC) and will last 18 months.

The team, led by Professor Jos Bengoechea, consists of leading researchers from the Wellcome-Wolfson Institute for Experimental Medicine (WWIEM) at Queens who are experts in virology, immunology and translational bioinformatics: Professor Ultan Power, Dr Connor Bamford, Dr Adrien Kissenpfennig; Dr David Simpson and Dr Guillermo Lpez-Campos.

The anticipated findings of the research will help to better manage severe Covid-19 patients and identify those at risk of complications due to the presence of bacterial co-infections.

And the research teams unique knowledge will be used to test the expected antiviral behaviour of FDA-approved drugs in the co-infection area. These drugs will be considered in clinical trials as new treatments for Covid-19.

Prof Bengoechea is Professor of Molecular Microbiology and Director of WWIEM at Queens University. He explained: There is an urgent need to develop new therapeutics to treat Covid-19 targeting the virus/bacteria co-infection scenario.

It is critical that bacterial co-infections should not be underestimated and instead be part of the plan to limit the global burden of morbidity and mortality during the Covid-19 pandemic and beyond.

We hope that our research exploring the role of bacterial and SARS-CoV-2 co-infections will result in finding better treatments to improve the health of Covid-19 patients and possibly even save lives.

Professor Stuart Elborn, Pro-Vice Chancellor for the Faculty of Medicine, Health and Life Sciences at Queens, said: Im delighted Queens has been awarded this grant from UK Research and Innovation to research the impact of bacterial co-infections in Covid-19.

This research project demonstrates Queens commitment to delivering positive impact on society and is an excellent opportunity for our researchers to use their collective expertise to improve our knowledge of this new virus and its complications to optimise the care of severely effected people with Covid-19.

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Queen's team work on link between bacterial co-infections and Covid-19 - Belfast Live