Depp undergoes an eerie transformation for this futuristic new sci-fi movie.

Johnny Depp is to undergo a cinematic transformation once again for new sci-fi thriller Transcendence. Directed by Wally Pfister, whose credits include Inception and The Prestige, the movie will star Depp as a scientist whose brain is uploaded to a supercomputer after his death.

Johnny Depp's New Film Sees The Actor Transformed Into An Automative Computer.

Will Caster (Depp) is a computer scientist at the forefront of artificial intelligence research, he is taken out by an anti-technology activist who stands against Caster's pioneering work into computer emotion. Determined not to die, the scientist and his wife Evelyn (Rebecca Hall) rush to find a way to upload his consciousness so that he can communicate even beyond the grave. However, not everybody is so sure of what will happen if they succeed, especially as Carter's mind begins to evolve.

Pfister's unnerving thriller explores a future of science without boundaries and the untold effect that merging robotics with human emotional intelligence can have upon mankind.

Watch The 'Transcendence' Trailer:

As an actor, Depp has been transformed into all manner of characters and creatures, from the Mad Hatter, to Willy Wonka to drunken pirate Jack Sparrow.

What about Johnny Depp's other new film, Mortdecai?

Transcendence will see him transformed into a highly intelligent computer in his first high-profile science fiction role alongside Morgan Freeman, Kate Mara, Cillian Murphy and Paul Bettany.

Not only is this sleek-looking movie the first solo-helmed project from Pfister, the director also calls upon rookie screenwriter Jack Paglen to produce a movie in the vein of Inception crossed with 2001: A Space Odyssey.

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Johnny Depp's New Sci-Fi Thriller 'Transcendence' Trailer Drops [Trailer]