Will we live forever or have the dubious honour of being one of the last few mortal generations? That was the fundamental question that I came to the SENS4 conference in Cambridge, UK to answer.
The conference included around 90 talks, most of them by academic biomedical researchers, many of whom from "serious" universities such as UCL, Cambridge University, etc. A typical topic would be "we have this hypothesis about how this part of the ageing process works, and we tested it in this trial/we built this device". Some of the talks were a little flaky, but the majority that I saw were either good or excellent.
Now, as far as conquering death for those people who are currently within a few decades of dying goes, we are going to have to do an awful lot more, and pull out a lot more stops than I saw evidence of at SENS; if there's one overriding impression I really want to avoid, it is the impression that now that SENS exists, the ageing problem is handled, for that would be a fatal mistake to make. The problem of ageing is a very hard one, primarily because the human body is very, very complicated and very, very messy. The average biomedical talk given at SENS, which represented the work of a few researchers for a total time of perhaps a few months to a year, would typically make some small increment of progress on some small subsystem of the human body, and in some cases that progress was the refutation of some previous promising piece of work.
In discussing the problems and challenges that anti-ageing science faces, the following slide from James Larrick's talk comes to mind:
The point at the bottom about ROS (Reactive Oxygen Species) relates to this recent study that showed that antioxidants negate the health-promoting effects of exercise; the theory being that ROS plays "both a creative (signalling) and a destructive (oxidative damage) role", so simply removing ROS does as much harm as good.
- Neurodiversity vs. Cognitive Liberty - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.13 - November 8th, 2009 [November 8th, 2009]
- Limits to the biolibertarian impulse - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.15 - November 8th, 2009 [November 8th, 2009]
- Neurodiversity vs. Cognitive Liberty, Round II - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.17 - November 8th, 2009 [November 8th, 2009]
- Cognitive liberty and right to one's mind - November 8th, 2009 [November 8th, 2009]
- TED Talks: Henry Markram builds a brain in a supercomputer - November 8th, 2009 [November 8th, 2009]
- And Now, for Something Completely Different: Doomsday! - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.19 - November 8th, 2009 [November 8th, 2009]
- Oklahoma and abortion - some fittingly harsh reflections - November 8th, 2009 [November 8th, 2009]
- Pigliucci on science and the scope of skeptical inquiry - November 8th, 2009 [November 8th, 2009]
- Remembering Mac Tonnies - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.24 - November 8th, 2009 [November 8th, 2009]
- Link dump: 2009.10.26 - November 8th, 2009 [November 8th, 2009]
- The Bright Side of Nuclear Armament - November 8th, 2009 [November 8th, 2009]
- Grieving chimps - November 8th, 2009 [November 8th, 2009]
- Elephant prosthetic - November 8th, 2009 [November 8th, 2009]
- Mass produced artificial skin to replace animal testing - November 8th, 2009 [November 8th, 2009]
- Dog gets osseointegrated prosthetic - November 8th, 2009 [November 8th, 2009]
- NASA Shuttle-derived Sidemount Heavy Launch Vehicle Concept - November 8th, 2009 [November 8th, 2009]
- Link dump for 2009.02.02 - November 8th, 2009 [November 8th, 2009]
- Link dump for 2009.11.04 - November 8th, 2009 [November 8th, 2009]
- Link dump for 2009.11.05 - November 8th, 2009 [November 8th, 2009]
- IEET's Biopolitics of Popular Culture Seminar - November 8th, 2009 [November 8th, 2009]
- Einstein and Millikan should have done a Kurzweil - November 8th, 2009 [November 8th, 2009]
- Affective Death Spirals - November 8th, 2009 [November 8th, 2009]
- Cure aging or give a small number of disabled people jobs as janitors? - November 8th, 2009 [November 8th, 2009]
- Would unary notation prevent scope insensitivity? - November 8th, 2009 [November 8th, 2009]
- Cure aging or give a small number of disabled people jobs as janitors - unary version. - November 8th, 2009 [November 8th, 2009]
- At SENS4, Cambridge, UK - November 8th, 2009 [November 8th, 2009]
- SENS4 top 10 photos - November 8th, 2009 [November 8th, 2009]
- My AI research for this year - November 8th, 2009 [November 8th, 2009]
- My AI research: Formal Logic - November 8th, 2009 [November 8th, 2009]
- My AI research: Category theory and institution theory - November 8th, 2009 [November 8th, 2009]
- My AI research: The Semantic Web - November 8th, 2009 [November 8th, 2009]
- My AI research: Features and Flaws of Logical representation - November 8th, 2009 [November 8th, 2009]
- My AI research: Graphical models and probabilistic logics - November 8th, 2009 [November 8th, 2009]
- Hughes and More engage Italian Catholicism: Image caption competition - November 8th, 2009 [November 8th, 2009]
- Surprisingly good solutions, falling in love and life in a materialistic universe - November 8th, 2009 [November 8th, 2009]
- What do you get when you cross slightly evolved, status seeking monkeys with the scientific method? - November 8th, 2009 [November 8th, 2009]
- Seeking the optimal philanthropic strategy: Global Warming or AI risk? - November 8th, 2009 [November 8th, 2009]
- Machine Learning - harbinger of the future of AI? - November 8th, 2009 [November 8th, 2009]
- At the Singularity Summit in NYC - November 8th, 2009 [November 8th, 2009]
- Katja Grace: world-dominating superintelligence is "unlikely" - November 8th, 2009 [November 8th, 2009]
- Normal Human Heroes on "Nightmare futures" - November 8th, 2009 [November 8th, 2009]
- Anissimov on Intelligence Enhancement - November 8th, 2009 [November 8th, 2009]
- Yudkowsky on "Value is fragile" - November 8th, 2009 [November 8th, 2009]
- Response to Pearce - November 8th, 2009 [November 8th, 2009]
- Creative thinking lets you believe whatever you want - December 13th, 2009 [December 13th, 2009]
- Let’s get metaphysical: How our ongoing existence could appear increasingly absurd - December 13th, 2009 [December 13th, 2009]
- Linda MacDonald Glenn guest blogging in November and December - December 13th, 2009 [December 13th, 2009]
- Link dump for 2009.11.15 - December 13th, 2009 [December 13th, 2009]
- Call 1-800-New-Organ, by 2020? - December 13th, 2009 [December 13th, 2009]
- IBM's claim to have simulated a cat's brain grossly overstated - December 13th, 2009 [December 13th, 2009]
- John Hodgman pulls off Fermi Paradox schtick - December 13th, 2009 [December 13th, 2009]
- Deus Sex Machina - December 13th, 2009 [December 13th, 2009]
- How Americans spent themselves into ruin... but saved the world - December 13th, 2009 [December 13th, 2009]
- I am my own grandpa (or grandma)? - December 13th, 2009 [December 13th, 2009]
- Link dump for 2009.11.29 - December 13th, 2009 [December 13th, 2009]
- The art of Tomas Saraceno - December 13th, 2009 [December 13th, 2009]
- Link dump: 2009.12.05 - December 13th, 2009 [December 13th, 2009]
- The Harmonic Convergence of Science, Sight, & Sound - December 13th, 2009 [December 13th, 2009]
- Working on my website - December 13th, 2009 [December 13th, 2009]
- Transhumanism, personal immortality and the prospect of technologically enabled utopia - December 13th, 2009 [December 13th, 2009]
- RokoMijic.com is up - December 13th, 2009 [December 13th, 2009]
- Why the Fuss About Intelligence? - December 13th, 2009 [December 13th, 2009]
- Initiation ceremony - December 13th, 2009 [December 13th, 2009]
- Birthing Gods - December 13th, 2009 [December 13th, 2009]
- 11 core rationalist skills - from LessWrong - December 13th, 2009 [December 13th, 2009]
- The best of the guests - December 13th, 2009 [December 13th, 2009]
- The best of Sentient Developments: 2009 - December 13th, 2009 [December 13th, 2009]
- Link dump: 2009.12.15 - December 15th, 2009 [December 15th, 2009]
- The Utopia Force - December 22nd, 2009 [December 22nd, 2009]
- Avatar: The good, the bad and ugly - December 23rd, 2009 [December 23rd, 2009]
- Singularity Institute launches "2010 Singularity Research Challenge" - December 24th, 2009 [December 24th, 2009]
- Transhumanism as a "nonissue" - December 24th, 2009 [December 24th, 2009]
- Hanson on "Meh, Transhumanism" - December 25th, 2009 [December 25th, 2009]
- Merry Newtonmas from Transhuman Goodness - December 25th, 2009 [December 25th, 2009]
- After proud knowledge - December 26th, 2009 [December 26th, 2009]