Walk-through cancer diagnoses and robotics muscles among groundbreaking projects backed by government – GOV.UK

Debilitating diseases such as cancer and osteoarthritis could be identified and treated faster and more effectively, thanks to 1 of 6 projects benefiting from 32 million government funding.

As part of a keynote speech on research and development at London Tech Week 2020, the Science Minister Amanda Solloway will today (Monday 7 September) announce 6 new projects aimed at developing revolutionary new technological approaches that aim to transform care and treatments in the NHS by 2050, helping to improve peoples quality of life as they age.

InlightenUs, led by the University of Edinburgh, will receive 5.4 million to use a combination of artificial intelligence (AI) and infra-red lasers to produce fast, high resolution 3D medical images, helping to identify diseases in patients more quickly.

Working with the universities of Nottingham and Southampton, the new research will initially be developed for use on hospital wards and GP surgeries, and by 2050 aims to scale up to walk through airport style X-Ray scanners, which will be able to pick up detailed images of structures often hidden within the human body that can reveal tumours.

Another of the 6 projects, emPOWER, will be led by researchers at the University of Bristol, and will receive 6 million to develop artificial robotic muscular assistance to help restore strength in people who have lost muscle capability. This could include patients who have suffered a stroke or are living with degenerative diseases such as sarcopenia and muscular dystrophy.

Using these highly targeted robotics will help overcome the limitations of current wearable assistive technology of regenerative medicine. Often, these technologies can be bulky and uncomfortable to wear, and can require 2 people to put on and take off. Users can also find the movements too slow. Through using robots, emPOWER will provide life changing benefits for sufferers, restoring their confidence, independence and quality of life, all while reducing the cost to the NHS.

Ahead of her keynote speech on R&D at London Tech Week, Science Minister Amanda Solloway said:

The pioneering projects we are backing today will help modernise healthcare, improving all of our lives now and into the future.

Todays announcement is part of our ambitious R&D Roadmap and underlines our commitment to back our incredible scientists and researchers and invest in ground-breaking research to keep the UK ahead in cutting-edge discoveries.

The funding is being delivered through the Engineering and Physical Sciences Research Council (EPSRC), part of UK Research and Innovation, through the Transformative Healthcare Technologies for 2050 call.

As part of her speech, Minister Solloway will set out the governments ambitions for research to address significant issues such as advancing healthcare outcomes for patients and ensuring the UK is at the forefront of transformational technologies like artificial intelligence.

It follows the launch of the governments R&D Roadmap in July 2020 which detailed plans to make the UK the best place in the world for scientists and researchers to live and work, building on the governments commitment to increase R&D public spending to 22 billion per year by 2024 to 2025.

Innovation minister Lord Bethell said:

Throughout this global pandemic, the NHS has continued to be there for us all and to treat cancer patients and those living with chronic illness as a priority.

These pioneering new projects will help us further improve care for patients and make life easier for NHS staff, cementing the UKs status as a world leader in research and technology and ultimately saving thousands of lives.

EPSRC Executive Chair, Processor Dame Lynn Gladden, said:

The projects announced today will develop new approaches which could become routine in the NHS and community and home care in the coming decades.

Harnessing the latest technologies and the UKs world-leading expertise will allow us to deliver a step-change in how healthcare is delivered and benefit millions of people, emphasising the critical role the UKs R&D sector plays in improving the health of the nation.

Led by Imperial College London, it will receive 5.5 million to develop a Non-Invasive Single Neuron Electrical Monitoring technology, which when combined with AI will allow researchers to monitor the brain in a way never achieved before. This will help scientists gain a better understanding of neurological diseases such as Parkinsons and Alzheimers. Currently approaches to monitoring the brain are invasive and so this new method would enable new pharmacological and neurotechnology-based treatments to be developed which are far more effective than any current treatments.

Led by Edinburgh Napier University, it will receive 3.2 million, to develop hearing aids designed to autonomously adapt to the nature and quality of their surroundings. Currently only 40% of people who could benefit from hearing aids have them, while most current devices make only limited use of speech enhancement. These hearing aids would be able to adapt to the nature and quality of the visual and acoustic environment around them, resulting in greater intelligibility of noise and potentially reduced listening effort for the listener.

Led by the University of Glasgow, it will receive 5.5 million to develop a project which aims to create a home of the future, providing homeowners with feedback on their health and wellbeing. Bringing clinically approved sensors into the living environment will enable individuals, carers or healthcare professional to monitor blood flow, heart rate and even brain function, in the home. Monitoring physical and emotional well-being in the home will enable tailored programmes to be built for lifestyles improvement, as well as rehabilitation.

Led by Heriot-Watt University, in partnership with the universities of Bath and Edinburgh, it will receive 6.1 million to exploit new laser, optical fibre and imaging technologies, delivering therapy for bacterial diseases and viruses in confined regions of the body such as the lungs, catheters inserted into the body for prolonged periods and areas of the body that have been subject to surgical procedures. The platform will be able to cut out single cells leaving the cells around it undamaged in cancer surgery, aiming to offer a cure for currently unresectable tumours tumours that are too close to critical structures and cannot be cut away safely with current approaches.

The Engineering and Physical Sciences Research Council (EPSRC), in collaboration with the Medical Research Council, will shortly be inviting proposals for adventurous projects as part of the second phase of the Transformative Healthcare Technologies for 2050 call.

This call will target projects that that are guided by a longer-term vision to pursue new, high risk high reward ideas and develop thinking and approaches supported by the next generation of underpinning science, engineering and emerging technologies in the healthcare space. We seek and encourage adventurous ideas, new thinking and collaborations that have the potential to significantly improve healthcare delivery by 2050. Read further details.

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Walk-through cancer diagnoses and robotics muscles among groundbreaking projects backed by government - GOV.UK

Stryker’s AxSOS 3 Ankle Fusion System Offers Innovative Plates That Are Designed to Fit a Range of Patients – BioSpace

Sept. 1, 2020 12:23 UTC

New System Includes Titanium Plates with Streamlined Instrumentation and Updated Screw Offerings

MAHWAH, N.J.--(BUSINESS WIRE)-- Stryker Trauma & Extremities division today announced the launch of its AxSOS 3 Ankle Fusion System, an ankle fusion titanium plate system intended for the fusion of the tibio-talar joint.

This press release features multimedia. View the full release here: https://www.businesswire.com/news/home/20200901005307/en/

Strykers Trauma & Extremities division today announced the launch of its AxSOS 3 Ankle Fusion System, an ankle fusion titanium plate system intended for the fusion of the tibio-talar joint. (Photo: Business Wire)

The AxSOS 3 Ankle Fusion System was developed using SOMA, Strykers proprietary orthopaedic design and development system that applies data from over 25,000 CT images of bones across different populations. As a result, these plates were designed to fit a range of patients with less customization.

The CP design utilized in Strykers forefoot and hindfoot plating systems served as the inspiration to take this technology into ankle fusions, said Keith Wapner, MD* at Penn Medicine, one of the design surgeons. As it relates to mechanical testing, Dr. Wapner said, Integrating the stability of plate fixation with the compression of the CP screw allows for a stable ankle fusion construct.

We combined Strykers CP technology from Anchorage 2 with the companys AxSOS 3 screw system and incorporated several additional instruments to assist with alignment and compression, said Michael Coughlin, MD* at UCSF Health, one of the design surgeons. The system is designed to provide surgeons with a dependable, user-friendly, intuitive technology option.

Additional information about AxSOS 3 Ti Ankle Fusion System can be found at: https://www.bit.ly/ANKLEFUSIONINFO

*Drs. Coughlin and Wapner are paid consultants of Stryker Orthopaedics.

About Stryker

Stryker is one of the worlds leading medical technology companies and, together with its customers, is driven to make healthcare better. The company offers innovative products and services in Orthopaedics, Medical and Surgical, and Neurotechnology and Spine that help improve patient and hospital outcomes. More information is available at http://www.stryker.com.

A surgeon must always rely on his or her own professional clinical judgment when deciding whether to use a particular product when treating a particular patient. Stryker does not dispense medical advice and recommends that surgeons be trained in the use of any particular product before using it in surgery.

The information presented is intended to demonstrate the breadth of Stryker's product offerings. A surgeon must always refer to the package insert, product label and/or instructions for use before using any of Stryker's products. Products may not be available in all markets because product availability is subject to the regulatory and/or medical practices in individual markets. Please contact your sales representative if you have questions about the availability of products in your area.

This is intended for US distribution only.

AXSOS-BL-3, 08-2020

View source version on businesswire.com: https://www.businesswire.com/news/home/20200901005307/en/

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Stryker's AxSOS 3 Ankle Fusion System Offers Innovative Plates That Are Designed to Fit a Range of Patients - BioSpace

Modifiable Risk Factors Associated With Transition From Psoriasis to Psoriatic Arthritis – AJMC.com Managed Markets Network

It may be possible to modify some lifestyle and environmental factors to reduce the risk of patients transitioning from psoriasis to psoriatic arthritis.

Psoriatic arthritis (PsA) occurs in approximately one-third of patients with psoriasis, but it may be possible to modify some lifestyle and environmental factors to reduce the risk of patients transitioning from psoriasis to PsA, according to research published in Journal of the American Academy of Dermatology.

PsA causes pain, swelling, and joint stiffness, and it is associated with impaired quality of life, a greater risk of comorbidities, and higher health care expenditures. The underlying events that cause the transition to PsA are not well understood, but current thought is that heredity and the environment both play a role.

determining the modifiable factors associated with transition to PsA among patients with psoriasis may provide a unique opportunity for early prevention and deepen our understanding of the etiology of PsA as well, the authors explained.

The researchers conducted a systematic search of PubMed, EMBASE, and Cochrane Library for observational studies reporting lifestyle or environmental factors for PsA onset in patients with psoriasis. The included 16 studies in their analysis. The studies originated from the United Kingdom (n = 6), Canada (n = 4), the United States (n = 4), Japan (n = 1), and Singapore (n = 1) and they included 322,967 patients.

Nine of the studies assessed the association between smoking and PsA. There were 8 studies on alcohol consumption in patients with psoriasis. Eight studies investigated the risk of PsA onset by body mass index (BMI). A total of 5 studies analyzed physical trauma and the presence of PsA.

The meta-analysis of BMI found a dose-dependent increase in the risk of developing PsA for patients with psoriasis. The risk increased 75% for patients with obesity. Despite the potential causal association between PsA and obesity, the underlining mechanisms are not completely understood, the authors wrote. They conjectured that chronic low-grade inflammation status in patients with obesity represents an increase in inflammatory cytokines and an alternation in adipokines, which might lead to the development of PsA in predisposed individuals.

The association between smoking and risk of PsA among patients with psoriaris remains unclear due to severely conflicting findings. One case-control study found a protective relationship, but more recently updated research using the same database showed smoking status was unrelated to PsA risk. However, another study using a large cohort of women found an elevated risk. The authors determined there was no association between smoking status (whether patients had ever smoked, currently smoked, or were past smokers) and the risk of developing PsA.

The authors did note a significant increase in the risk of developing PsA in patients with psoriasis who had had experienced traumatic injury. Individuals with psoriasis who are exposed to physical trauma, such as fracture, may transition from psoriasis to PsA.

The researchers did note their findings require caution since they were interpreting evidence from observational studies, which can be more biased than randomized controlled trials. In addition, not all the studies adjusted enough for potential confounders.

The results of the study highlight a need to strengthen public health to promote awareness and endeavor to reduce the risk of transition to PsA in psoriasis patients, and furthermore deepen our understanding of the etiology of PsA, the authors concluded.

Reference

Xie W, Huang H, Deng X, Gao D, Zhang Z. Modifiable lifestyle and environmental factors associated with onset of psoriatic arthritis in patients with psoriasis: a systematic review and meta-analysis of observational studies. J Am Acad Dermatol. Published online August 19, 2020. doi:10.1016/j.jaad.2020.08.060

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The TMS Round-Up: Our Favorite Cinematic Vacation Spots – The Mary Sue

Theres a lot to miss during a pandemic. Parties, movie theaters, licking strangers faces. But as another 3 day weekend rolls around, were mourning the loss of vacation. All we ever wanted? Yes. Have to get away? We wish. And while plenty of people are still traveling, Labor Day weekend is poised to become another COVID-19 hot spot holiday.

So what can we do, other than fill our living rooms with sand and turn our bathrooms into a swimming hole (dont do either of these, your landlord will be FURIOUS). We can take a virtual vacation via our favorite films and television series. We asked the TMS crew about their favorite cinematic vacation spots. From small towns to picturesque countrysides, weve got your streaming travel guide at the ready:

Jessica Mason:

The movie that always makes me want to travel is French Kiss. At first it seems like a travel disaster movie, what with poor Meg Ryan stranded in France with no bags or room or fiance, but it makes Paris and France look so welcoming, warm and beautiful. It truly captures the spirit of traveling where you discover something unexpected, authentic and truly unique along the way. Also, Kevin Kline is perfect and he can teach me how to taste wine any day.

Vivian Kane:

Ive been doing a Schitts Creek re-watch lately and Ive been amazed all over again by just how far the characters end up coming by the end of the series. Id forgotten that most of season one is about presenting the Rose family against the kooky backdrop of Schitts Creek and letting their snobbery run wild. But the Roses arent in this town for a mere vacation and eventually, as anyone whos done extended travelling or made a big geographical life change has probably experienced, the town becomes a part of their DNA. When Schitts Creek stops being just a backdrop and starts forcing the characters, unbeknownst to them, to start developing radical empathy towards themselves, their family, and their town, is when the show really becomes magic.

Kaila Hale-Stern:

The most recent movie about a vacation and traveling that I enjoyed the hell out of was Total Recall. I revisited the science fiction classic for the first time since childhood and had a great escapist time. Thats what Arnold Schwarzeneggers regular Joe character is trying to do when he signs up to have a virtual vacation to Mars, which has long fascinated him. But the vacation procedure takes an unexpected turn, leading him to go on a mission to the real Mars. Or is it all still in his mind?!

Rachel Leishman:

LOST is, surprisingly, a comforting show. Maybe because I watched these characters try and leave the island (and then return) when I was in high school? But whatever it is, I love to watch the passengers of Oceanic Flight 815 try and survive. Maybe LOST is why Im terrified of flying?

Chelsea Steiner:

Okay, no one wants to get eaten by a velociraptor, but hear me out. If someone told you there was a theme park with living dinosaurs, wouldnt you want to go? And if were going to O.G. Jurassic Park, technically the dinosaur breakout hasnt happened yet. What Im saying is, I want to lie on a breathing triceratops and cuddle those freshly hatched dino babies. Sure, things get dicier in Jurassic World, but at least there are margaritas!

Where would you go on your fictional vacation?

(image: POP TV)

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The Mary Sue has a strict comment policy that forbids, but is not limited to, personal insults toward anyone, hate speech, and trolling.

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The TMS Round-Up: Our Favorite Cinematic Vacation Spots - The Mary Sue

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TMS (Transcranial Magnetic Stimulation) Coil Market Share Analysis and Research – News by aeresearch

Latest update on TMS (Transcranial Magnetic Stimulation) Coil Market Analysis report published with an extensive market research, TMS (Transcranial Magnetic Stimulation) Coil market growth analysis and Projection by 2025. this report is highly predictive as it holds the over all market analysis of topmost companies into the TMS (Transcranial Magnetic Stimulation) Coil industry. With the classified TMS (Transcranial Magnetic Stimulation) Coil market research based on various growing regions this report provide leading players portfolio along with sales, growth, market share and so on.

TMS (Transcranial Magnetic Stimulation) Coil Market Report encompasses market attributes, size, growth forecast, segmentation, regional classifications, competitive landscape, TMS (Transcranial Magnetic Stimulation) Coil market shares, trends and tactics of TMS (Transcranial Magnetic Stimulation) Coil market. TMS (Transcranial Magnetic Stimulation) Coil Marketreport highlights key dynamics of Global TMS (Transcranial Magnetic Stimulation) Coil Industry sector. The potential of the TMS (Transcranial Magnetic Stimulation) Coil Market has been investigated along with the key challenges. The current TMS (Transcranial Magnetic Stimulation) Coil Market scenario and prospects of the sector has also been studied.

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As per the report, the TMS (Transcranial Magnetic Stimulation) Coil market has been further divided into crucial segments. A brief of the industry with regards to the market size in terms of the volume and renumeration aspects, as well as the current picture of TMS (Transcranial Magnetic Stimulation) Coil market has been included in the report. The research speaks about the information related to the geographical segment of this vertical along with the firms that have achieved a significant position across the marketplace.

TMS (Transcranial Magnetic Stimulation) Coil Market Report covers themanufacturers data, including shipment, price, revenue, gross profit, interview record, business distribution etc.,these data help the consumer know about the competitors better. This report also covers all theregions and countries of the world, which shows a regional development status, including TMS (Transcranial Magnetic Stimulation) Coil market size, volume and value, as well as price data.

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sTMS, rTMS and Others

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Executive Summary

Market Drivers, Challenges and Trends

Marketing, Distributors and Customer

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New Comprehensive Report on Transportation and Logistics Software Market to Witness an Outstanding Growth during 2020 2028 with Top Players Like TMW,…

Overview Of Transportation and Logistics Software Industry 2020-2028:

This has brought along several changes in This report also covers the impact of COVID-19 on the global market.

The Transportation and Logistics Software Market analysis summary by Reports Insights is a thorough study of the current trends leading to this vertical trend in various regions. Research summarizes important details related to market share, market size, applications, statistics and sales. In addition, this study emphasizes thorough competition analysis on market prospects, especially growth strategies that market experts claim.

Transportation and Logistics Software Market competition by top manufacturers as follow: TMW, Llamasoft, Avaal, 3G tms, FarEye, AFS Transportation Management, Manhattan, Descartes, BluJay Solutions, LogiNext Mile, Ramco Logistics Software, UltraShipTMS, Mettler Toledo, RouteSmart Technologies, ProTransport, Omnitracs Roadnet, VIP Delivery, ShipFusion, Phalanx

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The global Transportation and Logistics Software market has been segmented on the basis of technology, product type, application, distribution channel, end-user, and industry vertical, along with the geography, delivering valuable insights.

The Type Coverage in the Market are:

On-PremiseCloud-Based

Market Segment by Applications, covers:

Freight Forwarding CompaniesCourier Service ProvidersNetwork Service Providers

Market segment by Regions/Countries, this report coversNorth AmericaEuropeChinaRest of Asia PacificCentral & South AmericaMiddle East & Africa

Major factors covered in the report:

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The analysis objectives of the report are:

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Let’s kick the Golden Rule up to Platinum Rule – westvalleyview.com

I very much dislike the phrase new normal. News media has pounded us with this phrase more often in a few months than during the eight years of the Great Recession, when the term was coined. No one ever said, Microwave ovens are the new normal. Will some parts of our society change because of the virus? Definitely. Its called adaptation, and we are good at finding innovative ways to achieve goals. If you doubt that, think of one example of the new normal from the recession that is still around now. We adapted rather than accept a perceived necessity.

No matter what happens, there are aspects of life that will remain the same. Courtesy being one example. The Golden Rule of treating others the way you would like to be treated is common courtesy. Why not kick it up a notch with the Platinum Rule? Do unto others as they want to be treated. That rule has been the first thing I teach at customer-service classes. Its politeness and a happy attitude. Everybodys day becomes much easier, brighter and happier when some of us practice simple courtesy. Especially while driving.

Leadership is another quality that will always be around and be needed. More so when things get unexpectedly crazy. A boss barks orders at people sometimes using intimidation. A leader guides and directs using influence, inspiration and support. A step up would be the servant leader. Servant Leadership is a philosophy where the well-being of others is placed before that of the person in charge. This type of leader creates an atmosphere of trust, encourages open thoughts and ideas from everyone, develops leadership skills in others and has an unselfish mindset. Ive been told this style of management works at home, too. The entire organization (or family) becomes better.

How about caring and giving? Different from courtesy; its an emphatic reaction to a situation. The neighbor with whom I share a landing is a single mom with two kids. We exchange hellos on the very rare days when our schedules coordinate. If she happens to leave a trash bag on the landing, I take it to the dumpster on my way out. Am I a good neighbor? Id like to think so. Ive never been a parent, but I assume one less task that she has to do would be helpful. Think about bigger issues: homelessness, domestic violence, hungry families, veterans in need and the list goes on. Supporting our communitys charitable groups is one way to demonstrate our giving and caring nature. The nonprofit organizations will be grateful, too.

Change is part of life. Ive given three qualities that I feel should always be part of us or our society. I have more suggestions, but choosing core qualities is a personal decision. Standing true to your core beliefs will make adapting easier. Call it your new normal if you want. Begin by asking yourself, What do I want in my life to be inevitable?

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Let's kick the Golden Rule up to Platinum Rule - westvalleyview.com

What to Know: School daze, cool daze and all that – fortworthbusiness.com

School daze, cool days, oh those golden rule days.

To paraphrase that old song (from 1907!).

School days, school daysDear old golden rule days

reading and riting and rithmeticTaught via Zoom or some technology trick

The original ends with Taught to the tune of thehickry stick, but hey, thats a little old, old school.

My first school was Alice B. Carlson Elementary, where I was in kindergarten for a year. I was born late in August, so my parents thought I needed a little early education to catch me up to those folks born nearly a year before me. I dont know if it helped, but I do recall the colorful cartoon characters that surrounded the doors to our restroom facilities they were attached to the room as I remember. I knew then that the mouse was not Mickey and the duck was not Donald. I knew something was up.

Heres one of my favorite clean, I should mention Little Johnny jokes:

The teacher asked little Johnny if he has been studying his numbers while he has been working at home during COVID. Yes, he said. I do. My father taught me. Good. What comes after three? Four, answers the boy. What comes after six? Seven. Very good, says the teacher. Your dad did a good job. What comes after ten? A jack, says the boy.

So this week were going back to school. Weve got a story about the new president at Cristo Rey Fort Worth College Prep who took the reins at the school just as COVID was shutting things down.

See: New President at Cristo Rey deals with COVID challenges

We also have a column from T3, not the disappointing third installment of the Terminator franchise, but Tarrant To & Through (T3) Partnership, a new local coalition of school districts, colleges, universities, employers and community organizations.

Leveraging national best practices and building on existing efforts, the group is focused on providing direct services to boost the number of high school graduates who excel. Its key to developing a highly skilled, creative and motivated work force.

See: Student Success is OUR Success

See: Teaching Tech: Fort Worth ISD hoping rates fall to allow return to campus

The start of school means football. It makes me think of a couple of my teachers who would read Autumn Begins in Martins Ferry, Ohio by James Wright

Their sons grow suicidally beautiful

At the beginning of October,

And gallop terribly against each others bodies.

I remember Newell E. Faulkner, my junior English teacher reading the poem at R.L. Paschal High School with an actors perfection. You could hear the leaves falling as he read it.

Alas, this year football is problematic. The TCU-SMU game has been COVID canceled, so now you can not only bet on games, but also bet on whether they will play the games.

See: Coronavirus cases postpone TCU-SMU game, the seasons first college football matchup involving a Texas Big 12 team

But hey, theres hockey. Canada has its COVID caseload in order, so the Stars play on, freezing coronavirus out.

See: Stars captain Benn finally past 2nd round into West final

And the horses dont worry about COVID. They ran the Kentucky Derby this weekend and there were some surprises.

See: Authentic wins Kentucky Derby; Baffert notches 6th victory

Everyone seemed want to read what the late T. Boone Pickens has up for auction, from high end etchings by Picasso to an Onyx bathtub. Check out what the billionaire has to offer.

See: T.Boones auction

Heres a trivia question from Today in History:

Most of you can recall the Pledge of Allegiance, but can you recite the 1892 early version of The Pledge of Allegiance, written by Francis Bellamy? It appeared in The Youths Companion on this day in 1892. It went: I pledge allegiance to my Flag and the Republic for which it stands, one nation, indivisible, with liberty and justice for all.

Also today in history, in 1900, Galveston was struck by a hurricane that killed an estimated 8,000 people.

See: Today in History

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What to Know: School daze, cool daze and all that - fortworthbusiness.com

Letters to the Editor – Politics of fear, voting, the Golden Rule, Republican convention, Vice President – The Dallas Morning News

Fomenting fear from one side

Re: Dont give in to politics of fear, by Gromer Jeffers Jr., Monday Metro column.

I was shocked when I read Jeffers column urging readers to not be frightened by doomsday messages of our presidential contenders. Perhaps he was trying to be balanced and fair, but his perspective about not letting the candidates scare you reminded me of President Donald Trump saying, There are good people on both sides. I agree that Trump is fomenting fear it is his normal technique for the last almost four years. I do not know what world Jeffers is living in these days, but Joe Bidens message is consistently about healing and coming together in formal and informal conversation.

To equate Trumps fearmongering with Bidens messages of hope and recovery in no way represents reality. Jeffers has a loud megaphone and as with many other readers, I have counted on him to tell it like it is. It is the duty of the free press to inform the people and to state clearly when the king is naked and call out lies and hypocrisy.

Jeffers calls on us to do our research and determine which candidates plan for the future best serves us. Since Trump has no plan, that cuts our research time in half.

Liz Wally, Old East Dallas

Voters saw in 2016 President Donald Trumps campaign tactics and have witnessed his brand of presidency for the past four years. It is safe to assume that his current campaign and future presidency will be more of the same.

The Democratic candidates must present detailed plans of what they intend to do, how they will accomplish it and what impacts it will have on our nation and the world. Those who vote want and need facts, not more political platitudes and tasteless bashing of the opposition.

We, as a nation, are facing many serious challenges from many directions. We, as the electorate, must have trustworthy facts and direction prior to casting our votes for those who we decide will be leading us for the next four years.

Stewart K. Wysong, Richardson

What a refreshing change to watch positive messaging from the pro-America Republican speakers versus the doom and gloom Democrats at the recent conventions. When the Democratic platform consists only of bashing President Donald Trump, raising taxes, and shutting down the country again it was difficult to stomach.

Americas best days can still be ahead, but only if we as a people embrace God again. The Golden Rule can only be followed if you understand what it means. The blessing on America is evaporating at an alarming rate because we have become spiritually bankrupt.

I fear judgment is upon us because we have drifted into a secular society, thinking the government will solve all our problems. The Scriptures are replete with warnings of what will happen to a nation that once had the light and rejects it. I pray that people will return to God for any chance that our land will be healed.

Anton Skell, Plano

As we watched the Republican National Convention, we were told to fear the America that will result if the other side gains power. It is claimed that this America would be one of anarchy, chaos, unrest, divisiveness and guns on the street. Wait a minute! Arent these images the images of Trumps America? The America of right here, right now under his watch after over 3 1/2 years? What am I missing? My secret agent decoder ring seems to be lost in the mail.

Sharon Lathrop, Richardson

There is enough conservative viewpoint ammo for conservatives to use against Democratic candidates that using misleading material should be unnecessary. Vice President Mike Pence, nonetheless, went ahead and implied to convention watchers that David Patrick Underwood, a federal officer, was murdered by Black Lives Matter protesters during riots in Oakland, Calif. It appears (no trial/conviction yet) that he was murdered by a white supremacist who subscribes to the idea that such murders will lead to a desired race war. He is not a member of the protesters and our vice president knew it.

Shelton G. Hopkins, Dallas

If you want to talk politics, our 45th president has not only achieved tremendous success on his own but he has also helped our country do the same. And sadly through it all he has gone through tremendous hate and torment by everyone, including his own employees. Now that takes heart to withstand and hey, America, he has also fought for our second stimulus package, our additional unemployment benefits, our safety and even our own economy.

So give him a break. You want to talk politics? Ive seen politics in action and President Donald Trump is a great, great man! Vote for whom you want to vote for, but think first before putting down our incumbent. Its rude, crude and makes you sound uneducated. Either way, go vote because that is what makes Americas democracy work.

Ashley Barg, Dallas

I always thought the press was to provide news and information to all subscribers. What happened to that? As I read my Dallas Morning News, all I can find is Trump-bashing, including Letters to the Editor. I used to submit letters pertaining to my experiences in the Vietnam Air War and my 50-year career in aviation attempting to correct some perceptions. Many of those were published.

Now, because Trump-bashing is top priority, I will refrain from any more submissions. I have a deep respect for my country, as most combat veterans and others do, and that includes respecting our president. I have never met the man and I dont think the bashers have either. I have witnessed many presidents in the past, each one very unique and very human, trying to do the job as best they could.

Robert J. Ponti, Far North Dallas

Click here to submit a letter to the editor. Be sure to include sources.

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Letters to the Editor - Politics of fear, voting, the Golden Rule, Republican convention, Vice President - The Dallas Morning News

The smile behind the mask – CBS News

I had to run to the grocery store the other day to pick up a couple of things.

Watching the cashier behind her protective plastic partition, ringing up my loaf of bread and a couple of bottles of seltzer, I was hit with this surge of gratitude. No, she wasn't a doctor or nurse in a COVID ward, but she was certainly exposing herself to a lot more risk every day than I do.

I wanted to express my thanks, make sure she knew how deeply I appreciated her essential service. So, I locked eyes with her, and smiled the warmest, widest smile I could muster.

She looked at me blankly and didn't say a word. It was almost as if she hadn't seen my smile at all.

I was leaving the store when it hit me: of course she hadn't seen my smile! My mask had concealed my gratitude.

For the rest of the day, with every interaction I had with someone I didn't know the gas station attendant, the kid behind the take-out counter I made sure to tell them how thankful I was, my words replacing the smiles they couldn't see.

But still, something was missing.

Smiles are the grease for our interpersonal communications, our most efficient way to signal warmth, safety, empathy, compassion, or at the grocery store gratitude a non-verbal supplement to expand the limits of what words alone can express.

Studies have shown smiles are actually contagious. They lift the mood of both the source and the target of the smile. And now, COVID has robbed us of this critically-important tool we use to connect with each other.

We've been sad before as a country, living without smiles for a time in the aftermath of assassinations, terror attacks, school shootings. But this is different. Wearing masks is a structural change in the way we live. COVID has literally wiped the smiles from our faces.

So, keep this in mind as you go about your business, for now our words are all we've got. Not just the ones we choose, but how we deliver them. From behind a mask, tone and inflection are the new smiles. Forget the face-to-face world. In a mask-to-mask world, the golden rule is that people can't feel what they can't see.

Let's all be part of the solution, and find other ways to smile at each other.

Continued here:

The smile behind the mask - CBS News

Please respect each other and their opinions | Columns – HNGnews.com

Those who know me know that I am a man with great pride for our country, our state, and our community. However, I am extremely disappointed in what I have seen from so many over the last few years. That disappointment does not lie with any one political candidate or political party, but rather with some in our communities who have chosen to be disrespectful of others property and their opinions. I hope and pray that there is an improvement in the way that we treat one another. It seems that some have forgotten the golden rule that we all learned when we were growing up, do unto others as you would have them do unto you.

Freedom of speech and respect for others is such an important topic right now. There are many in our country who, whether they know it or not, have created more division than we have ever seen before. Again, I am not referring to politicians or any political party. Yes, they make decisions regarding governing, but we the people have the power to control the narrative. Our voices are louder now than ever before. That is possible through the power of the internet, videos, and social media.

Social media has so many positives that allow us to stay connected and share memories. Social media has also turned our country on one another. Perhaps thats because it allows us to sit behind a keyboard not having to speak to someone face to face. As a result, there is very little chance of repercussions. Regardless of the reason, our country has changed and I am fearful of the future we are leaving for our children.

Unfortunately, social media typically has two types of disagreements. In the first type, people disagree. At the end of the conversation, they agree to disagree and they remain friends. I have several friends like this and I enjoy having a debate and considering their perspectives. The second type is unfortunately much more common and unpleasant. This is when two or more people share their opinions, followed by angry outbursts, hateful comments, or threatening statements. People become intolerant of each others opinions and hateful stereotypes are often a result. These stereotypes have only one purpose, to intimidate that person while also shaming others who might share that same opinion into keeping it to themselves.

Recently, I had several residents here in Dodge County tell me that they fear sharing their opinions. They are afraid of the backlash from others who are intolerant. This includes refusing to openly support a candidate, placing a campaign sign in their yard, or even having a discussion with friends or family. This is unfortunate because it is intimating someone into forfeiting their constitutional right.

I undoubtedly will be the subject of these hateful comments following this column. That too is unfortunate but does not bother me as I stand by my convictions and respectfully refuse to be bullied. At the same time, I will respect the opinions of others, and will not shy away from a friendly debate. Remember that no one can bully you in the ballot box and social media bullies are just people typing words on a website, nothing more.

I hope that eventually, our country returns to one of mutual respect for differences of opinion. It will not happen overnight, but if the majority of us begin to recognize the problem and refuse to tolerate hateful speech, we can begin to make a needed change so Dodge County can continue to be a great place to live, work, and visit.

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Please respect each other and their opinions | Columns - HNGnews.com

Society could benefit from this set of rules – The Chatham News + Record

BY BOB WACHS, Columnist

As a civilized society although when I see the news lately Im starting to wonder our nation has all kinds of laws, rules and regulations (or regs).

Some are asinine and/or completely foolish at least to me. For instance, the Internal Revenue Tax Code for pastors, which applies to part of my life, is a booklet about four inches thick. By contrast, the Gettysburg Address soars to great heights with just 270 words.

I imagine the contents of the tax code and other laws and rules and regs are like many laws passed by Congress such as the one some months ago, when the Speaker of the House chided other members to get the bill passed so we can read it. I may be old and have been born at night, but it wasnt last night. I thought you read those things before they became the law of the land.

Others laws and rules and regs, by comparison, are either, as my late wise father said, fair to middling or quite helpful. Personally, Im glad its unlawful to rob, steal, kill or otherwise create mayhem, although there doesnt seem to be an overabundance of enforcement of those in some parts lately. And, of course, there are rules, regs, and laws at all levels. Its not a federal violation, for instance, to dump trash alongside N.C. Hwy. 751 or the Pittsboro-Goldston Road, but local folks take offense to such behavior.

To me, the bottom line is if mankind would treat his or her fellow creature with a little more of the milk of human kindness, there would be little or no need for a tractor-trailer load of do this or dont do that. Thats where Biblical admonitions that we call the Golden Rule of treating other folks like you want to be treated or the Ten Commandments not the Ten Good Ideas or the Ten Suggestions engraved boldly over the U.S. Supreme Court building in D.C. comes in.

Ive been a big fan of the Golden Rule for years, thanks to my mama. The cynical part of me does admit that there could be a problem if someone really wanted you to beat the tar out of them and so they treated you that way. Deep down inside, though, I dont think most folks are like that but someone could be. So I think maybe we ought to amp up that idea and operate under the norm of do unto others better than youd like to be done to. Wouldnt it be a hoot if everyone acted that way?

Im also pretty sure the Ten Commandments have been around long enough and have enough of a track record to prove their worth if wed just pay attention to them. And there are some natural laws that still are in effect. I did not make a career of physics, didnt even expose myself to it at ol Pittsboro High School, especially since the other class at that hour was advanced phys ed, but I do understand that two objects cannot occupy the same space at the same time, such as two cars at the stop sign at the same time. When that happens, we call it a wreck.

That brings me to a point that rules, regs and laws keep our society from completely falling apart, and I still have hope and faith that wont happen just yet.. But I still say if our hearts were bit more as they should be, we could all do better. Not so long ago a friend gave me a list of what she called Golden Rules for Living. Consider these if you will:

If you open it, close it.

If you turn it on, turn it off.

If you unlock it, lock it.

If you move it, put it back.

If it belongs to someone else, get permission to use it.

If you borrow it, return it.

If you dont know how to operate it, leave it alone.

If you use it, take care of it.

If you break it, admit it.

If you cant fix it, call someone who can.

If you mess it up, clean it up.

If its none of your business, dont ask questions.

Could it be that if we lived by those rules wed need fewer rules?

I think maybe so. You?

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Society could benefit from this set of rules - The Chatham News + Record

IOWA STRONG: Willie Ray’s Q Shack gives out free food with help from ‘Advocates for Social Justice’ – kwwl.com

CEDAR RAPIDS, Iowa (KWWL) - 'Treat people the way you want to be treated' is the golden rule Willie Fairley has been following since the derecho hit.

The owner of Willie Ray's Q Shack has been handing out free food almost every day. On Friday, he teamed up with the 'Advocates for Social Justice'.

The Q shack is located on Blairs Ferry Rd in Cedar Rapids, but Fairley wanted to get closer to the community.

Burgers, ribs, beans, and more were coming straight off the grill and into peoples' hands all day Friday. Some people even tried to donate money, but Fairley refused.

"When you have a passion for people and you just have to do the right thing, and doesn't matter how long we do it," Fairley said. "We just gonna do it until everyone needs it. And it could be six months from now someone needs something. We still want to be there. We want to be that rally call to make sure everyone has what they need."

He says the support he has been getting from the community is unbelievable and he plans on continuing to hand out food for at least a few more weeks.

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IOWA STRONG: Willie Ray's Q Shack gives out free food with help from 'Advocates for Social Justice' - kwwl.com

COVID-19: How to Safely Enjoy Fall Activities Health Essentials from Cleveland Clinic – Health Essentials from Cleveland Clinic

Like most things in 2020, fall will look and feel different this year compared to last. But with a little planning and caution, you can still enjoy some of falls signature activities during the coronavirus (COVID-19) pandemic.

Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services.Policy

Instead of focusing on all the changes, its really about shifting our expectations and reimagining how to do some of the same activities, explains family medicine specialist Neha Vyas, MD.

There are still plenty of things we can safely do, we just need to take precautions to protect ourselves and those around us, which from time to time, might mean passing on an event or activity if those precautions cant be followed, she says.

Maintaining at least six feet from other people is key, and for times when that isnt possible, wearing a face mask is crucial. And if you havent already caught on, hand sanitizer and hand washing will continue to be the coolest trends of the season.

Dr. Vyas shares some insight, advice and modifications for a safe fall.

Parents and kids alike are wondering about Halloween this year. But how do you handle trick-or-treating, costumes and passing out candy in the middle of a global pandemic?

Your city will determine if trick-or-treating is happening or not, says Dr. Vyas. If it is, then its really about deciding as a family what youre comfortable with and how youll protect yourself and those around you. If your city has determined that trick-or-treating will be canceled, everyone will need to respect that rule as well.

Parents who allow their kids to trick-or-treat will need to consider quite a few things: How will your child maintain social distance from others? How many houses will they be allowed to visit? How will you help your child keep their hands clean and not touch their face?

And then of course, theres the concept of incorporating a face mask (and no, were not talking a Spiderman mask) into your childs costume.

Children who are trick-or-treating (and parents who are out with them) will still need to wear a proper face mask, aka it covers the mouth and nose, has multiple layers and ties around the ears or back of the head.

Get creative and encourage your child to think about how their face mask can be part of their costume, says Dr. Vyas. Opt for a mask that matches the costumes style, or have them pick a costume where a face mask is an essential part like a doctor or a ninja. And as long as your child can still see and breathe fine and theres plenty of ventilation, you can layer a Halloween mask over a cloth face mask.

When you get back home, you might be wondering if you should sanitize your childs candy haul, but according to Dr. Vyas, its not really necessary.

The transmission of coronavirus on surfaces is very low, she says. But if you feel safer doing it, than by all means do.

If youve opted not to go out trick-or-treating, but still want to pass out candy, consider leaving candy and hand sanitizer out on a table at the end of your driveway. You can even sit farther back from the table so you can enjoy the evening from a distance. Or, you can designate one person with clean hands to pass out candy. Unfortunately this year, experts say to avoid having kids pick directly from the bowl because it could spread more germs. Its also advised to skip on passing out homemade goods.

If youve decided that youre not comfortable with Halloween outside of your direct household (which is perfectly OK!), get creative and have some fun with how youll celebrate:

Just because were spending more time at home these days doesnt mean we have to skip every fall activity we once loved. With a little organization, preparation and creativity its possible to still enjoy some of your favorite fall events.

The trick (to this treat) is reimaging and setting the correct expectation. Youll also want to keep the golden rules of COVID-19 in mind: Wear a face mask, social distance, dont touch your face, wash your hands regularly and stay home if you arent feeling well.

Heres what else to keep in mind for several popular fall festivities:

We know this year has been a bummer for many things and events. But just as we learned in the spring and summer, if were safe, we can still enjoy some activities theyll just look and feel a little different.

Theres still time to enjoy the great outdoors and local parks this fall, so take a socially distanced hike and pack a picnic. Enjoy a family car ride to enjoy the fall foliage when the weather turns cool, or hold a faux tailgate in your driveway. Rake leaves, perfect your apple pie recipe or warm up next to a campfire on a crisp night.

Coronavirus doesnt have to take all the fun out of everything, says Dr. Vyas. If we all practice and respect the safety guidelines, we can slow the spread of the virus and still experience things that bring us joy.

And dont worry, pumpkin spice lattes are fall 2020 approved for the occasional splurge, of course!

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COVID-19: How to Safely Enjoy Fall Activities Health Essentials from Cleveland Clinic - Health Essentials from Cleveland Clinic

Fall Gem Show opens in Tucson with COVID-19 precaution measures – KVOA Tucson News

TUCSON (KVOA) - After the "JOGS Tucson Gem & Jewelry Show" was approved by the City of Tucson and the Pima County Health Department three weeks ago, the annual show is now open through Sunday at the Tucson Expo Center.

We don't know when (COVID-19) is going away," Irene Mayzenberg JOGS organizer said. "So we have to adjust to what is happening and live in a new environment."

Safety rules are being strictly enforced at the show.

Officials say more security has been added for the event, and there will be strict enforcement of the wearing of masks.

People have already been escorted out for not complying with the mask-wearing regulations.

Social distancing markers are also in multiple places along the floor of the Tucson Expo Center.

"It was supposed to be six feet," said Mayzenberg. "We made it seven to eight feet distancing."

"I think a lot of people have been really knowledgeable about how they need to take care of themselves first," said vendor Arthi Nihalani of Precious Treasures. "The customers are being careful. They're not touchy, feeling, so it's good. "

All COVID-19 safety precautions aside, vendors who have been struggling with so many closures, are grateful to be back at work.

"I am very, very thankful to the city of Tucson who gave permission for the JOGS show to do this show," Mike Karayan, who sells turquoise, said.

Nihalini said she is also mindful of social distancing while showing off her jewelry.

"(We're) just making sure that we aren't too close in proximity with customers," she said.

That is a shining example of the golden rule in this line of work:"Do unto others as you would have --GEM-- do to you."

Below is a statement issued by JOGS Tucson Gem & Jewelry Show DirectorYelen Masenkno.

"We are grateful to the City of Tucson for allowing us to conduct a Show because it gives our exhibitors, their employees and all the buyers' hope. All local businesses and Tucson economy will be positively impacted (restaurants, hotels, car rental services, grocery stores and many more).

Our JOGS exhibitors and attendees are thrilled to start conducting business after a long break and to support economy to get back on track! Our vendors shared with us that they were waiting to start participating in the trade shows which is the main part of their business operations, and were be able to rehire some of their employees.

We are getting many calls from the local and out of state retailers who are glad to finally see their gem and jewelry suppliers, manufacturers, jewelry designers, and miners and start conducting business again. Even thou some of our international exhibitors could not make to the show due to the travel restrictions we have a wide diversity of products presented at the event.

Minerals, gems, huge geodes, crystals, silver and gold jewelry, diamonds, Swarovski crystals, gems, cabochons, chains, findings - everything that retailers and private buyers are looking for to re-stock and get ready for the holiday season.

Our JOGS Tucson Gem and Jewelry Show will look different this year, with safety protocols to reduce Covid-19 transmission risk:

1. Face masks are required on the show floor at all times, no exceptions. Pima County Police will be on-site to enforce the mask/face covering mandate at the Event.

2. Capacity management to reduce crowd sizes will be enforced. We welcome everyone but want to let you know about the potential for lines. We advise you to pre-print your show badges/passes to eliminate waiting in registration lines.

3. Frequent disinfection and throughout cleaning of high-traffic areas/ surfaces will be regularly performed.

4. Hand sanitizer stations will be sited throughout the JOGS Tucson Show.

5. Wide aisles between booths will promote practicing 6-foot social distancing.

6. Temperature checks will take place for all attendees of the JOGS Tucson Show upon entry of the Tucson Expo Center.

The safety of our JOGS Show attendees and exhibitors is our priority!"

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Fall Gem Show opens in Tucson with COVID-19 precaution measures - KVOA Tucson News

Florida Reopens Long Term Care Facilities to Visitors. Will It Be Safe? – WLRN

On this Wednesday, Sept. 2, episode of Sundial:

Joan Hipler has been using Facetime to communicate with her mother every day. Hipler is a registered nurse and she used to visit her mother at the Five Star Premier Residences of Hollywood before the coronavirus pandemic struck.

I promised my dad (who passed) that I would be there for her and that I would take care of her, until she met up with him. So I would go everyday, she said in a previous interview with Sundial.

Visitations to long term care facilities have been banned since the middle of March, one of the first executive orders taken by Gov. Ron DeSantis as the pandemic began to spread in Florida.

But the governor announced Tuesday that visitors can begin to visit elder care facilities under very strict guidelines. Nursing homes, ALFs and retirement communities will need to have adequate personal protective equipment and regular testing of nursing home staff.

For Hipler, the new rules are life changing and she's looking forward to doing some of what she used to do when she would visit her mother.

I would like to hold her hand. I would like to sing with her. She and I used to sing. Id like to keep her stimulated because shes had a whole lack of stimulation during this time, Hipler said.

Floridas elderly population living in long term care facilities have been the hardest hit by the coronavirus pandemic. Of the 11,501 residents whove died from this virus, 4,759 of those deaths have occurred within nursing homes more than 40 percent of the deaths in the state.

Gov. DeSantis recognized the visitations will lead to an increase in cases but during a news conference in Jacksonville argued its worth it for these families to see their loved ones.

We focused Wednesday's entire program on the issue of elder care during COVID-19. WLRNs health care reporter Vernica Zaragovia joined us as well as Joan Hipler, Renee Garvin, executive director at The Vi at Aventura Retirement Community, and Peter and Veronica Fuchs, two seniors living at The Vi.

The Fuchs host a Facebook Live everyday where they perform for others in the community.

Below are excerpts from the panel conversation.

WLRN: Veronica, help us understand what these new standards include?

ZARAGOVIA: Theres a list that includes for example, all guests and staff have to have PPE and masks have to be worn. There cannot be an onset of COVID-19 in the last 14 days, no new cases in the facility. And then if a staff member tests positive, then they have to cease visitations. They have to have adequate capacity at referral hospitals at the facility. For those reasons, it will take a few days for facilities to get ready.

There will also be a limitation on who can come in.

ZARAGOVIA: Every resident can choose up to five visitors who can come in and there can only be two at once. They can choose an essential caregiver. This is a person who can feed, or bath or change their relative or loved ones. That person can give a hug but nobody else can, everyone else would need to be socially distanced.

Renee, The Vi has approached this pandemic differently. Residents have been able to come and go. How have you ensured theres no outbreaks and keep residents safe?

GARVIN: We have a full continuum of care. We have independent living, assisted living, memory support, skilled nursing and rehabilitation. Where our residents are able to come and go is in independent living. Residents arent able to leave when it comes to assisted living unless they have doctors appointments. We work really hard to make sure we are screening anyone coming into our community, we make sure to have gloves, masks and face shields.

We are going to continue to recommend outdoor visitors whenever possible because it is the safest. But we are also gearing up to support indoor visits as well but making sure we are meeting all those requirements. We are big on face shields here, we will probably offer face shields to visitors as well. We are going to look to make sure everyone coming into the community to spend that time with their loved one but make sure theyre doing it in a safe way.

Peter Fuchs, you are a musician. And youre also a Holocaust survivor. You have a perspective that many of us dont have. Everything you see our country going through now, what advice would you give to all of us?

Peter Fuchs

PETER FUCHS: Well we should be handling it according to the golden rule. Dont do to others what you dont want done to yourself. And try to have a positive attitude towards life and try and enjoy everyday because its a gift. Thats my simple answer, the rest I say in music.

VERONICA FUCHS: Well this is actually a little bit like what happened in Europe. They couldnt go out, they couldnt communicate with everybody out there. Its a similar thing, this is the invisible enemy. There was a real enemy in those days. So its kind of similar.

PETER FUCHS: Shes right. For the first time since I left Europe and left that whole life behind me, I felt like we are in a warlike situation. I feel its that serious. Its stopped everything in America, it stopped life like we know it.

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Florida Reopens Long Term Care Facilities to Visitors. Will It Be Safe? - WLRN

Reel Buzz: Vs result proves the golden rule again – Telugubulletin.com

(Do you want to make an impact with your content? Interested in writing Movie or Politics or General stories? contact us at [emailprotected])

It is well known that story and screenplay form the heart and soul of any film regardless of its star cast and this is regarded as the golden rule in the film industry. We have seen many films with huge star cast and combinations bomb at the box office due to the lack of gripping story and screenplay.

Recently, films like Gang Leader, Vinaya Vidheya Rama, and Ruler released amidst good buzz. However, they put on a bad show at the box office as they lacked good story and compelling screenplay.

Now, Nanis V has proven the golden rule right again. The film built up good buzz, thanks to the fact that it is Nanis landmark, 25th film. Also, the combination of Nani, Sudheer Babu and Mohankrishna Indraganti upped the expectations. However, none of these factors worked in favour of the film.

V is being criticized by the viewers for lack of proper story and screenplay. The film got off to a rather poor response. Many say that the makers should have concentrated more on the story and screenplay rather than setting up interesting combinations. The Mohankrishna Indraganti directorial has broken the above-mentioned golden rule and is now paying the price for the same.

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Reel Buzz: Vs result proves the golden rule again - Telugubulletin.com

US Open — Novak Djokovic not the only one to have officials derail a championship run – ESPN

Sep 6, 2020

Jeremy WillisESPN.com

On Sunday, Novak Djokovic, the top-ranked men's player at the US Open, was defaulted from his fourth-round match after hitting a ball that struck a line judge.

The match's umpire and officials conferred and ruled to default Djokovic, essentially ejecting him from the tournament. The United States Tennis Association said that it's justified by the rule book, "in accordance with the Grand Slam rulebook, following his actions of intentionally hitting a ball dangerously or recklessly within the court or hitting a ball with negligent disregard of the consequences."

Despite what seemed like no malicious intent, Djokovic is out, leaving a tournament already missing Roger Federer and Rafael Nadal, wide open. There are two other fairly recent examples of similar rulings in tennis events, according to the Associated Press. In 2017, Denis Shapovalov was defaulted from a Davis Cup match when he accidentally hit the chair umpire in the face with a ball. At Wimbledon in 1995, Tim Henman hit a ball into the head of a ball girl and was defaulted from a doubles match.

While some offenses are worse than others, and it doesn't happen often in championship events, breaking the rules is breaking the rules and a player is ousted by officials. Sometimes, it affects the results of the game.

1 Related

Here are some other occasions when refs and rule-breaking changed a championship.

1968 Masters: It appeared Roberto De Vicenzo would meet Bob Goalby in an 18-hole playoff after finishing tied at the 1968 Masters. However, De Vicenzo's playing partner marked an incorrect, one-stroke-higher score for a hole. De Vicenzo did not catch the error and signed his scorecard. The rule states a golfer has to take the higher score. Goalby won the Masters, his only major title, by that one-stroke mistake.

1985 World Series, Game 7: The St. Louis Cardinals' Joaquin Andujar was the last player to be ejected from a World Series while actively playing in the game. Andujar was ejected by plate umpire Don Denkinger, one pitch after Cards manager Whitey Herzog was ejected for arguing balls and strikes. Andujar charged Denkinger and bumped him before being restrained by teammates. The game was out of hand, with the Kansas City Royals up big, when both Herzog and Andujar were ejected, so this was more frustration and didn't affect the final results.

2006 World Cup: In extra time, France's Zinedine Zidane, after being provoked by Italy's Marco Materazzi, head-butted Materazzi. Zidane received a red card and was sent off. Zidane was one of the French team's top scorers, and he wasn't available when the match went to penalty kicks. Italy would win 5-3 in penalty kicks.

2009 US Open Women's semifinal: In the match against Kim Clijsters, Serena Williams was assessed a foot fault penalty. Then Williams subsequently argued the call and was given a point penalty. Without a point to give, Williams lost the match, and Clijsters would win the US Open.

2010 World Cup final: In the first period of extra time (109th minute), John Heitinga of the Netherlands received his second yellow card of the match for a slide tackle on Spain's Andres Iniesta, calling for an ejection. Iniesta would go on to score the match-deciding goal just seven minutes later, giving Spain its first World Cup title.

2011 Stanley Cup Final, Game 3: The game had been in action for just over five minutes when Vancouver Canucks defenseman Aaron Rome checked Nathan Horton of the Boston Bruins in the head after he had already dished the puck, sending Horton crashing to the ice. Horton was taken off the ice on a stretcher and diagnosed with a concussion. In addition to being penalized and ejected, Rome was suspended for the remaining four games of the series. Following Rome's ejection, the Canucks were outscored 21-4 the rest of the series, which Boston won 4-3.

2013 Federated Auto Parts 400: This was the final race leading into the Chase for the Sprint Cup. Three teams (Michael Waltrip Racing, Penske Racing and Front Row Motorsports) had attempted to manipulate the finish of the race as well as Chase positions. As a result, Michael Waltrip Racing was fined $300,000, the largest fine a team had received in NASCAR history. Additionally, Clint Bowyer and Martin Truex Jr. were docked 50 driver points, removing them from wild-card position.

2016 NBA Finals, Game 4: Golden State Warriors forward Draymond Green had already racked up three flagrant fouls in the playoffs. Toward the end of Game 4 against the Cleveland Cavaliers, Green became angry with LeBron James, who stepped over Green while he was on the floor. Green swung his arm and appeared to make contact with James' groin. The following day, Green received his fourth flagrant foul and was suspended for Game 5, becoming the first player to be suspended from the NBA Finals since 2006. Green also was Golden State's top defender, and with him out, James and Cavs point guard Kyrie Irving combined to score 82 points. This allowed Cleveland to pull closer at 3-2 in the series, before winning the title in seven games.

2020 College Football Playoff National Championship game: In a controversial ruling, Clemson linebacker James Skalski was ejected in the third quarter of the title matchup because of a targeting hit on LSU wide receiver Justin Jefferson. Trailing 28-25 at the time, Clemson's offense couldn't help a defense without its second-leading tackler. LSU would score the next 14 points to win 42-25.

Research from ESPN Stats and Information contributed to this story.

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US Open -- Novak Djokovic not the only one to have officials derail a championship run - ESPN

Complementary and Alternative Medicine Market : Global Forecast Over 2024 – Owned

Alternative medicines include treatments other than allopathic. Alternative medicine treatments include systems with healing ability such as acupuncture, acupuncture, naturopathy, herbal remedies, and homeopathy. The medical profession does not regard these healing systems as orthodox treatment systems. Some of these treatments are accepted to be of value for certain conditions. Herbal medicines include drugs that are derived from plants. Herbal medicines are either used for therapeutic purpose, or as supplements to improve well-being or health. Herbal products are available as teas, extracts, powders, capsules, tablets, and others. These products are natural, hence considered to be safe. Herbal medicines have the ability to cure almost all the types of diseases.

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Nutraceutical is a combination of the words nutrition and pharmaceutical. Nutraceutical medicines or products are fortified food or food products that provide supplementary diet and also help in prevention and treatment of diseases except anemia. Nutraceuticals are not regulated and tested to the extent of pharmaceutical drugs. These have the ability to treat diseases including ADHD, amyotrophic lateral sclerosis, anemia, sickle cell, anxiety, aphthous ulcer, carnitine deficiency, depression, dietary supplementation, dyspareunia, eye conditions, fibromyalgia, herbal supplementation, herpes simplex, herpes simplex, suppression, high cholesterol, Huntingtons disease, hypertriglyceridemia, insomnia, jet lag, muscle pain, nonalcoholic fatty liver disease, osteoarthritis, Parkinsons disease, peripheral neuropathy, premenstrual dysphoric disorder, rheumatoid arthritis, short bowel syndrome, and smoking cessation.

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Probiotics are live yeasts and bacteria that benefit the health of individuals. These are referred as healthy, helpful, or good bacteria. An imbalance of natural yeasts or bacteria within the body has been associated with a range of indications including suppressed immune system, yeast infections, skin rashes, weight gain, diarrhea, and constipation. Probiotics may be taken orally to restore any imbalance in the normal urogenital or intestinal flora. These are available as contained naturally, or dietary supplements or added to foods such as kefir, sauerkraut, or yogurt. Increase in inclination toward safe and lesser side effects boosts the global alternative medicines market. Rise in side effects and adverse drug reactions due to usage of allopathic medicines drives the market. Surge in awareness about the benefits relating to alternative medicines is a key driver of the market. However, slow healing ability of alternative medicines restrains the market.

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The global alternative medicines market can be segmented based on drug class, dosage form, disease indication, distribution channel, and region. In terms of drug class, the market can be categorized into herbal products, nutraceutical products, and probiotics. Based on dosage form, the global alternative medicines market can be classified into tablets, powder, syrup, capsules, teas, extracts, and others. In terms of disease indication, the market can be divided into ADHD, amyotrophic lateral sclerosis, anemia, sickle cell, anxiety, aphthous ulcer, carnitine deficiency, depression, dietary supplementation, dyspareunia, eye conditions, fibromyalgia, herbal supplementation, herpes simplex, herpes simplex, suppression, high cholesterol, Huntingtons disease, hypertriglyceridemia, insomnia, jet lag, muscle pain, nonalcoholic fatty liver disease, osteoarthritis, Parkinsons disease, peripheral neuropathy, premenstrual dysphoric disorder, rheumatoid arthritis, short bowel syndrome, smoking cessation, and others. Based on distribution channel, the global alternative medicines market can be categorized into online pharmacies, retail pharmacies, and hospital pharmacies.

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Geographically, the global alternative medicines market can be segmented into Latin America, Asia Pacific, Europe, North America, and Middle East & Africa. North America held the largest market share in 2016 due to extensive awareness and acceptance by the large population in the region. Europe held the second largest market share in 2016 owing to increased awareness and sale of alternative medicines in drug stores. The global alternative medicines market in Asia Pacific is projected to grow at a rapid pace during the forecast period from 2017 to 2025. The market in Middle East & Africa and Latin America are expected to witness moderated growth during the forecast period due to rise in demand for food supplements and natural health.

Key players in the global alternative medicines market include Dr. Willmar Schwabe India Pvt. Ltd., GUNA S.p.a., BIORON GmbH, Ainsworth, Inc., Kanak Drishti Infotech Pvt. Ltd., and Random Beauty, Inc.

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Complementary and Alternative Medicine Market : Global Forecast Over 2024 - Owned

New England Journal of Medicine Publishes Positive Results from Phase 2 WILLOW Study of Brensocatib in Patients with Non-Cystic Fibrosis…

BRIDGEWATER, N.J., Sept. 7, 2020 /PRNewswire/ -- Insmed Incorporated (Nasdaq:INSM), a global biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases, today announced that final results from the Phase 2 WILLOW study of brensocatib in patients with non-cystic fibrosis bronchiectasis (NCFBE) were published online in the New England Journal of Medicine (NEJM). New data from subgroup analyses of the WILLOW study also were presented today during a late-breaking clinical trials session at the virtual European Respiratory Society (ERS) International Congress 2020. Brensocatib is a novel, first-in-class, oral, reversible inhibitor of dipeptidyl peptidase 1 (DPP1) being developed by Insmed for the treatment of bronchiectasis and other inflammatory diseases.

"We are very pleased that NEJM has recognized the significance of the Phase 2 WILLOW data for patients with NCFBE. These results demonstrate the potential clinical benefits of directly reducing neutrophil-mediated inflammation in bronchiectasisa critical finding for patients who currently suffer from severe outcomes in the absence of an approved therapy," said Martina Flammer, M.D., MBA, Chief Medical Officer of Insmed. "We eagerly anticipate initiating our Phase 3 program for brensocatib in bronchiectasis later this year as we work to bring this urgently needed solution to patients."

The results published today showed that brensocatib significantly prolonged time to first pulmonary exacerbation, the primary endpoint, over the 24-week treatment period for both treatment doses versus placebo (p=0.03 for the 10 mg group; p=0.04 for the 25 mg group). The risk of exacerbation at any time during the trial was reduced by 42% for the 10 mg group versus placebo (HR 0.58, p=0.03) and by 38% for the 25 mg group versus placebo (HR 0.62, p=0.046).

Treatment with brensocatib also reduced the rate of pulmonary exacerbations, a key secondary endpoint. Patients treated with brensocatib experienced a 36% reduction in the 10 mg arm (p=0.04) and a 25% reduction in the 25 mg arm (p=0.17), compared with the placebo arm. In addition, mean concentrations of active neutrophil elastase (NE) in sputum showed dose-dependent reductions compared with placebo over the 24-week treatment period.

Importantly, study results were consistent among subgroups based on age, baseline NE concentrations, prior exacerbation history, bronchiectasis severity index, and lung function.

"The WILLOW study demonstrated that among patients with NCFBE who have a history of frequent exacerbations, treatment with brensocatib significantly prolonged the time to first exacerbation and reduced the risk of exacerbation over the treatment period. Annualized rates of exacerbation were also lower compared to placebo," said lead author James Chalmers, MBChB, Ph.D., Professor and Consultant Respiratory Physician at the School of Medicine, University of Dundee, UK. "These results are critically important given the lack of approved pharmaceutical therapies to reduce the risk of exacerbationthe major driver of morbidity and mortality in patients with bronchiectasis. The results also validate the novel mechanism of action of brensocatib and highlight the potential benefits of reducing neutrophil serine protease activity."

In addition to the results published in NEJM, new data from the WILLOW study were presented today at the ERS International Congress. Subgroup analyses showed that brensocatib consistently prolonged time to first exacerbation and reduced rates of exacerbation among patient subgroups analyzed by baseline disease severity, P. aeruginosa infection, and sputum NE concentration. Further, brensocatib reduced the sputum concentrations of all three neutrophil serine proteases (NSPs) assessed (NE, proteinase 3, and cathepsin G).

Brensocatib was generally well-tolerated in the WILLOW study. Rates of adverse events (AEs) leading to drug discontinuation in patients treated with placebo, brensocatib 10 mg, and brensocatib 25 mg were 11%, 7%, and 7%, respectively. The most common AEs in patients treated with brensocatib were cough, headache, sputum increase, dyspnea, infective exacerbation of bronchiectasis, and diarrhea.

Rates of adverse events of special interest (AESIs) in patients treated with placebo, brensocatib 10 mg, and brensocatib 25 mg, respectively, were as follows: rates of skin events (including hyperkeratosis) were 12%, 15%, and 24%; rates of dental events were 4%, 16%, and 10%; and rates of infections considered AESIs were 18%, 14%, and 17%. Hyperkeratosis was reported in 1/85, 3/81, and 1/89 patients treated with placebo, brensocatib 10 mg, and brensocatib 25 mg, respectively. The study included extensive dental evaluations to closely monitor progression of periodontal disease. The results did not raise a signal about dental safety. The percentage of patients with change in periodontal pocket depth 2 mm and absolute value of 5 mm (the threshold of concern for periodontal disease) were 12%, 11%, and 12% for placebo, brensocatib 10 mg, and brensocatib 25 mg, respectively. No skin or dental adverse events were considered serious.

Brensocatib received breakthrough therapy designation from the U.S. Food and Drug Administration in June 2020 for the treatment of adult patients with NCFBE for reducing exacerbations. Insmed plans to initiate a Phase 3 program for brensocatib in bronchiectasis by the end of 2020.

About WILLOW

WILLOW was a randomized, double-blind, placebo-controlled, parallel-group, multi-center, multi-national, Phase 2 study to assess the efficacy, safety and tolerability, and pharmacokinetics of brensocatib administered once daily for 24 weeks in patients with non-cystic fibrosis bronchiectasis (NCFBE). WILLOW was conducted at 116 sites and enrolled 256 adult patients diagnosed with NCFBE who had at least two documented pulmonary exacerbations in the 12 months prior to screening. Patients were randomized 1:1:1 to receive either 10 mg or 25 mg of brensocatib or matching placebo. The primary efficacy endpoint was the time to first pulmonary exacerbation over the 24-week treatment period in the brensocatib arms compared to the placebo arm.

About Brensocatib

Brensocatib is a small molecule, oral, reversible inhibitor of dipeptidyl peptidase I (DPP1) being developed by Insmed for the treatment of patients with bronchiectasis. DPP1 is an enzyme responsible for activating neutrophil serine proteases (NSPs), such as neutrophil elastase, in neutrophils when they are formed in the bone marrow. Neutrophils are the most common type of white blood cell and play an essential role in pathogen destruction and inflammatory mediation. In chronic inflammatory lung diseases, neutrophils accumulate in the airways and result in excessive active NSPs that cause lung destruction and inflammation. Brensocatib may decrease the damaging effects of inflammatory diseases such as bronchiectasis by inhibiting DPP1 and its activation of NSPs.

About Non-Cystic Fibrosis Bronchiectasis

Non-cystic fibrosis bronchiectasis (NCFBE) is a severe, chronic pulmonary disorder in which the bronchi become permanently dilated due to a cycle of infection, inflammation, and lung tissue damage. The condition is marked by frequent pulmonary exacerbations requiring antibiotic therapy and/or hospitalizations. Symptoms include chronic cough, excessive sputum production, shortness of breath, and repeated respiratory infections, which can worsen the underlying condition. NCFBE affects approximately 340,000 to 520,000 patients in the U.S. Today, there are no approved therapies specifically targeting NCFBE in the U.S., Europe, or Japan.

About Insmed

Insmed Incorporated is a global biopharmaceutical company on a mission to transform the lives of patients with serious and rare diseases. Insmed's first commercial product, ARIKAYCE (amikacin liposome inhalation suspension), is the first and only therapy approved in the United States for the treatment of refractory Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug regimen for adult patients with limited or no alternative treatment options. MAC lung disease is a chronic, debilitating condition that can cause severe and permanent lung damage. Insmed is also advancing brensocatib, a novel oral reversible inhibitor of dipeptidyl peptidase 1 with therapeutic potential in bronchiectasis and other inflammatory diseases, and treprostinil palmitil, an inhaled formulation of a treprostinil prodrug that may offer a differentiated product profile for rare pulmonary disorders, including pulmonary arterial hypertension. For more information, visit http://www.insmed.com.

Forward-looking Statements

This press release contains forward-looking statements that involve substantial risks and uncertainties. "Forward-looking statements," as that term is defined in the Private Securities Litigation Reform Act of 1995, are statements that are not historical facts and involve a number of risks and uncertainties. Words herein such as "may," "will," "should," "could," "would," "expects," "plans," "anticipates," "believes," "estimates," "projects," "predicts," "intends," "potential," "continues," and similar expressions (as well as other words or expressions referencing future events, conditions or circumstances) may identify forward-looking statements.

The forward-looking statements in this press release are based upon the Company's current expectations and beliefs, and involve known and unknown risks, uncertainties and other factors, which may cause the Company's actual results, performance and achievements and the timing of certain events to differ materially from the results, performance, achievements or timing discussed, projected, anticipated or indicated in any forward-looking statements. Such risks, uncertainties and other factors include, among others, the following: the risk that brensocatib does not prove effective or safe for patients in future clinical studies, including the STOP-COVID19 study; business or economic disruptions due to catastrophes or other events, including natural disasters or public health crises; impact of the novel coronavirus (COVID-19) pandemic and efforts to reduce its spread on our business, employees, including key personnel, patients, partners and suppliers; failure to successfully commercialize or maintain U.S. approval for ARIKAYCE, the Company's only approved product; uncertainties in the degree of market acceptance of ARIKAYCE by physicians, patients, third-party payors and others in the healthcare community; the Company's inability to obtain full approval of ARIKAYCE from the FDA, including the risk that the Company will not timely and successfully complete the study to validate a PRO tool and complete the confirmatory post-marketing study required for full approval of ARIKAYCE; inability of the Company, PARI or the Company's other third party manufacturers to comply with regulatory requirements related to ARIKAYCE or the Lamira Nebulizer System; the Company's inability to obtain adequate reimbursement from government or third-party payors for ARIKAYCE or acceptable prices for ARIKAYCE; development of unexpected safety or efficacy concerns related to ARIKAYCE or brensocatib; inaccuracies in the Company's estimates of the size of the potential markets for ARIKAYCE or brensocatib or in data the Company has used to identify physicians; expected rates of patient uptake, duration of expected treatment, or expected patient adherence or discontinuation rates; the Company's inability to create an effective direct sales and marketing infrastructure or to partner with third parties that offer such an infrastructure for distribution of ARIKAYCE; failure to obtain regulatory approval to expand ARIKAYCE's indication to a broader patient population; failure to successfully conduct future clinical trials for ARIKAYCE, brensocatib and the Company's other product candidates, including due to the Company's limited experience in conducting preclinical development activities and clinical trials necessary for regulatory approval and the Company's inability to enroll or retain sufficient patients to conduct and complete the trials or generate data necessary for regulatory approval; risks that the Company's clinical studies will be delayed or that serious side effects will be identified during drug development; failure to obtain, or delays in obtaining, regulatory approvals for ARIKAYCE outside the U.S. or for the Company's product candidates in the U.S., Europe, Japan or other markets, including the United Kingdom as a result of its recent exit from the European Union; failure of third parties on which the Company is dependent to manufacture sufficient quantities of ARIKAYCE or the Company's product candidates for commercial or clinical needs, to conduct the Company's clinical trials, or to comply with laws and regulations that impact the Company's business or agreements with the Company; the Company's inability to attract and retain key personnel or to effectively manage the Company's growth; the Company's inability to adapt to its highly competitive and changing environment; the Company's inability to adequately protect its intellectual property rights or prevent disclosure of its trade secrets and other proprietary information and costs associated with litigation or other proceedings related to such matters; restrictions or other obligations imposed on the Company by its agreements related to ARIKAYCE or the Company's product candidates, including its license agreements with PARI and AstraZeneca AB, and failure of the Company to comply with its obligations under such agreements; the cost and potential reputational damage resulting from litigation to which the Company is or may become a party, including product liability claims; the Company's limited experience operating internationally; changes in laws and regulations applicable to the Company's business, including any pricing reform, and failure to comply with such laws and regulations; inability to repay the Company's existing indebtedness and uncertainties with respect to the Company's ability to access future capital; and delays in the execution of plans to build out an additional FDA-approved third-party manufacturing facility and unexpected expenses associated with those plans.

The Company may not actually achieve the results, plans, intentions or expectations indicated by the Company's forward-looking statements because, by their nature, forward-looking statements involve risks and uncertainties because they relate to events and depend on circumstances that may or may not occur in the future. For additional information about the risks and uncertainties that may affect the Company's business, please see the factors discussed in Item 1A, "Risk Factors," in the Company's Annual Report on Form 10-K for the year ended December 31, 2019, our Quarterly Report on Form 10-Q for the quarter ended March 31, 2020 and any subsequent Company filings with the SEC.

The Company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date of this press release. The Company disclaims any obligation, except as specifically required by law and the rules of the SEC, to publicly update or revise any such statements to reflect any change in expectations or in events, conditions or circumstances on which any such statements may be based, or that may affect the likelihood that actual results will differ from those set forth in the forward-looking statements.

Contact:

Investors:

Argot PartnersLaura Perry or Heather Savelle(212) 600-1902Insmed@argotpartners.com

Media:

Mandy FaheySenior Director, Corporate CommunicationsInsmed(732) 718-3621amanda.fahey@insmed.com

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SOURCE Insmed Incorporated

Company Codes: NASDAQ-NMS:INSM

Excerpt from:

New England Journal of Medicine Publishes Positive Results from Phase 2 WILLOW Study of Brensocatib in Patients with Non-Cystic Fibrosis...