Reproductive system – Wikipedia

The reproductive system or genital system is a system of sex organs within an organism which work together for the purpose of sexual reproduction. Many non-living substances such as fluids, hormones, and pheromones are also important accessories to the reproductive system.[1] Unlike most organ systems, the sexes of differentiated species often have significant differences. These differences allow for a combination of genetic material between two individuals, which allows for the possibility of greater genetic fitness of the offspring.[2]

In mammals, the major organs of the reproductive system include the external genitalia (penis and vulva) as well as a number of internal organs including the gamete producing gonads (testicles and ovaries). Diseases of the human reproductive system are very common and widespread, particularly communicable sexually transmitted diseases.[3]

Most other vertebrate animals have generally similar reproductive systems consisting of gonads, ducts, and openings. However, there is a great diversity of physical adaptations as well as reproductive strategies in every group of vertebrates.

Vertebrate animals all share key elements of their reproductive systems. They all have gamete-producing organs or gonads. In females, these gonads are then connected by oviducts to an opening to the outside of the body, typically the cloaca, but sometimes to a unique pore such as a vagina or intromittent organ.

The human reproductive system usually involves internal fertilization by sexual intercourse. During this process, the male inserts his erect penis into the female's vagina and ejaculates semen, which contains sperm. The sperm then travels through the vagina and cervix into the uterus or fallopian tubes for fertilization of the ovum. Upon successful fertilization and implantation, gestation of the fetus then occurs within the female's uterus for approximately nine months, this process is known as pregnancy in humans. Gestation ends with birth, the process of birth is known as labor. Labor consists of the muscles of the uterus contracting, the cervix dilating, and the baby passing out the vagina (the female genital organ). Human's babies and children are nearly helpless and require high levels of parental care for many years. One important type of parental care is the use of the mammary glands in the female breasts to nurse the baby.[4]

The female reproductive system has two functions: The first is to produce egg cells, and the second is to protect and nourish the offspring until birth. The male reproductive system has one function, and it is to produce and deposit sperm. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, numerous differences typically occur in secondary sexual characteristics.

The male reproductive system is a series of organs located outside of the body and around the pelvis region of a male that contribute towards the reproduction process. The primary direct function of the male reproductive system is to provide the male sperm for fertilization of the ovum.

The major reproductive organs of the male can be grouped into three categories. The first category is sperm production and storage. Production takes place in the testes which are housed in the temperature regulating scrotum, immature sperm then travel to the epididymis for development and storage. The second category are the ejaculatory fluid producing glands which include the seminal vesicles, prostate, and the vas deferens. The final category are those used for copulation, and deposition of the spermatozoa (sperm) within the male, these include the penis, urethra, vas deferens, and Cowper's gland.

Major secondary sexual characteristics includes: larger, more muscular stature, deepened voice, facial and body hair, broad shoulders, and development of an adam's apple. An important sexual hormone of males is androgen, and particularly testosterone.

The testes release a hormone that controls the development of sperm. This hormone is also responsible for the development of physical characteristics in men such as facial hair and a deep voice.

The human female reproductive system is a series of organs primarily located inside of the body and around the pelvic region of a female that contribute towards the reproductive process. The human female reproductive system contains three main parts: the vagina, which leads from the vulva, the vaginal opening, to the uterus; the uterus, which holds the developing fetus; and the ovaries, which produce the female's ova. The breasts are involved during the parenting stage of reproduction, but in most classifications they are not considered to be part of the female reproductive system.

The vagina meets the outside at the vulva, which also includes the labia, clitoris and urethra; during intercourse this area is lubricated by mucus secreted by the Bartholin's glands. The vagina is attached to the uterus through the cervix, while the uterus is attached to the ovaries via the fallopian tubes. Each ovary contains hundreds of egg cells or ova (singular ovum).

Approximately every 28 days, the pituitary gland releases a hormone that stimulates some of the ova to develop and grow. One ovum is released and it passes through the fallopian tube into the uterus. Hormones produced by the ovaries prepare the uterus to receive the ovum. The lining of the uterus, called the endometrium, and unfertilized ova are shed each cycle through the process of menstruation. If the ovum is fertilized by sperm, it attaches to the endometrium and the fetus develops.

Most mammal reproductive systems are similar, however, there are some notable differences between the non-human mammals and humans. For instance, most male mammals have a penis which is stored internally until erect, and most have a penis bone or baculum. Additionally, males of most species do not remain continually sexually fertile as humans do. Like humans, most groups of mammals have descended testicles found within a scrotum, however, others have descended testicles that rest on the ventral body wall, and a few groups of mammals, such as elephants, have undescended testicles found deep within their body cavities near their kidneys.[5]

The reproductive system of marsupials is unique in that the female has two vaginae, both of which open externally through one orifice but lead to different compartments within the uterus; males usually have a two-pronged penis which corresponds to the females' two vaginae. Marsupials typically develop their offspring in an external pouch containing teats to which their newborn young (joeys) attach themselves for post uterine development. Also, marsupials have a unique prepenial scrotum.[6] The 15mm (5/8 in) long newborn joey instinctively crawls and wriggles the several inches (15cm), while clinging to fur, on the way to its mother's pouch.

The uterus and vagina are unique to mammals with no homologue in birds, reptiles, amphibians, or fish.[citation needed] In place of the uterus the other vertebrate groups have an unmodified oviduct leading directly to a cloaca, which is a shared exit-hole for gametes, urine, and feces. Monotremes (i.e. platypus and echidnas), a group of egg-laying mammals, also lack a uterus and vagina, and in that respect have a reproductive system resembling that of a reptile.

In domestic canines, sexual maturity (puberty) occurs between the ages of 6 to 12 months for both males and females, although this can be delayed until up to two years of age for some large breeds.

The mare's reproductive system is responsible for controlling gestation, birth, and lactation, as well as her estrous cycle and mating behavior. The stallion's reproductive system is responsible for his sexual behavior and secondary sex characteristics (such as a large crest).

Male and female birds have a cloaca, an opening through which eggs, sperm, and wastes pass. Intercourse is performed by pressing the lips of the cloacae together, which is sometimes knowna intromittent organ which is known as a phallus that is analogous to the mammals' penis. The female lays amniotic eggs in which the young fetus continues to develop after it leaves the female's body. Unlike most vertebrates female birds typically have only one functional ovary and oviduct.[7] As a group, birds, like mammals, are noted for their high level of parental care.

Reptiles are almost all sexually dimorphic, and exhibit internal fertilization through the cloaca. Some reptiles lay eggs while others are viviparous (animals that deliver live young). Reproductive organs are found within the cloaca of reptiles. Most male reptiles have copulatory organs, which are usually retracted or inverted and stored inside the body. In turtles and crocodilians, the male has a single median penis-like organ, while male snakes and lizards each possess a pair of penis-like organs.

Most amphibians exhibit external fertilization of eggs, typically within the water, though some amphibians such as caecilians have internal fertilization.[8] All have paired, internal gonads, connected by ducts to the cloaca.

Fish exhibit a wide range of different reproductive strategies. Most fish however are oviparous and exhibit external fertilization. In this process, females use their cloaca to release large quantities of their gametes, called spawn into the water and one or more males release "milt", a white fluid containing many sperm over the unfertilized eggs. Other species of fish are oviparous and have internal fertilization aided by pelvic or anal fins that are modified into an intromittent organ analogous to the human penis.[9] A small portion of fish species are either viviparous or ovoviviparous, and are collectively known as livebearers.[10]

Fish gonads are typically pairs of either ovaries or testes. Most fish are sexually dimorphic but some species are hermaphroditic or unisexual.[11]

Invertebrates have an extremely diverse array of reproductive systems, the only commonality may be that they all lay eggs. Also, aside from cephalopods, and arthropods, nearly all other invertebrates are hermaphroditic and exhibit external fertilization.

All cephalopods are sexually dimorphic and reproduce by laying eggs. Most cephalopods have semi-internal fertilization, in which the male places his gametes inside the female's mantle cavity or pallial cavity to fertilize the ova found in the female's single ovary.[12] Likewise, male cephalopods have only a single testicle. In the female of most cephalopods the nidamental glands aid in development of the egg.

The "penis" in most unshelled male cephalopods (Coleoidea) is a long and muscular end of the gonoduct used to transfer spermatophores to a modified arm called a hectocotylus. That in turn is used to transfer the spermatophores to the female. In species where the hectocotylus is missing, the "penis" is long and able to extend beyond the mantle cavity and transfer the spermatophores directly to the female.

Most insects reproduce oviparously, i.e. by laying eggs. The eggs are produced by the female in a pair of ovaries. Sperm, produced by the male in one testis or more commonly two, is transmitted to the female during mating by means of external genitalia. The sperm is stored within the female in one or more spermathecae. At the time of fertilization, the eggs travel along oviducts to be fertilized by the sperm and are then expelled from the body ("laid"), in most cases via an ovipositor.

Arachnids may have one or two gonads, which are located in the abdomen. The genital opening is usually located on the underside of the second abdominal segment. In most species, the male transfers sperm to the female in a package, or spermatophore. Complex courtship rituals have evolved in many arachnids to ensure the safe delivery of the sperm to the female.[13]

Arachnids usually lay yolky eggs, which hatch into immatures that resemble adults. Scorpions, however, are either ovoviviparous or viviparous, depending on species, and bear live young.

Among all living organisms, flowers, which are the reproductive structures of angiosperms, are the most varied physically and show a correspondingly great diversity in methods of reproduction.[14] Plants that are not flowering plants (green algae, mosses, liverworts, hornworts, ferns and gymnosperms such as conifers) also have complex interplays between morphological adaptation and environmental factors in their sexual reproduction. The breeding system, or how the sperm from one plant fertilizes the ovum of another, depends on the reproductive morphology, and is the single most important determinant of the genetic structure of nonclonal plant populations. Christian Konrad Sprengel (1793) studied the reproduction of flowering plants and for the first time it was understood that the pollination process involved both biotic and abiotic interactions.

Fungal reproduction is complex, reflecting the differences in lifestyles and genetic makeup within this diverse kingdom of organisms.[15] It is estimated that a third of all fungi reproduce using more than one method of propagation; for example, reproduction may occur in two well-differentiated stages within the life cycle of a species, the teleomorph and the anamorph.[16] Environmental conditions trigger genetically determined developmental states that lead to the creation of specialized structures for sexual or asexual reproduction. These structures aid reproduction by efficiently dispersing spores or spore-containing propagules.

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Reproductive system - Wikipedia

Rotunda – The Center for Human Reproduction

Welcome to Rotunda The Center for Human Reproduction Our website is a place where you can learn about the services and staff at Rotunda.

We know that facing infertility can be one of the most stressful situations you may encounter, emotionally, physically and sometimes financially. At Rotunda, we work hand-in-hand with you to make every phase of the process from diagnosis to treatment as predictable and comfortable as possible. Together we will map out a plan to determine the cause of your infertility and an appropriate course of action. Many problems can easily be corrected with medication or surgical procedures. For couples facing more difficult challenges, our ART program ranks amongst the best in the nation.

We know that when you visit an infertility clinic you may be worried about a procedure, a result, or your next step. Our staff is here to answer all your questions, offer support, and make any procedure as comfortable as possible. Our goal is to provide our patients with state-of-the-art medical care and an environment that fosters the best possible outcome.

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Rotunda - The Center for Human Reproduction

Presentation | World Congress on Human Reproduction 2015

Dear Colleagues, The International Academy of Human Reproduction (IAHR) will host the next World Congress on Human Reproduction 2015 in Berlin. We invite you to mark the date, location and themes of this prestigious conference. Starting in 1974 in Rio de Janero, the IAHR has held successful World Congress every three years in Europe, Asia, Africa, the Americas and Australia. The IAHR Scientific Program Committee will put together a phenomenal program including presentations by international experts on a range of subjects. The Berlin Congress in 2015 will focus on state of the art and innovative topics, looking forward to the future of human reproduction. The more scientific-specific themes will address the new challenges posed by globalization and new technologies.

These, combined with more complex ethical, clinical, social norms, religious beliefsand costs are areas which clinicians and scientists must tackle on a daily basis. Learning new skills has always been the Academys role and we shall intensify this in the 2015 Berlin Congress. Today modern Berlin is the open-minded scientific and cultural melting pot of East and West Europe. Berlin is an exciting city of contrasts. Thousands of restaurants, hundreds of theatres, operas, and museums are waiting for you. Every year, millions of people from all over the world are enjoying one of the most interesting cities of Europe.

Herzlich Willkommen in Berlin 2015! Welcome to Berlin 2015!

President of the CongressMettler Liselotte (DE) Holzgreve Wolfgang (DE) Local Organizing Committee Beier Henning (DE) Birkhauser Martin (CH) Buchholz Tina (DE) Dietrich Klaus (DE) Ebert Andreas (DE) Egarter Christian (AT)Halis Guelden (DE) Huber Johannes (AT) Kentenich Herbert (DE) Kiesel Ludwig (DE) Mechsner Sylvia (DE) Rabe Thomas (DE) Tandler-Schneider Andreas (DE) Stumm Markus (DE) Thaler Christian (DE) Tinneberg Hans (DE)Tunn FR. (DE)

President Joseph G. Schenker (IL)

Executive Andrea R. Genazzani (IT) Liselotte Mettler (DE) John Sciarra (US) Martin Birkhuser (CH)

Members * Elected in 2014 Adamyan Leyla (RU) Barri Pedro (ES) Benagiano Giuseppe (IT) Beier Henning (DE) Ben-Rafael Zion (IL) Buchholz Tina (DE)* Coutifaris Christos (US) Creatsas George (GR) De Cherney Alan (US) Devoto Luigi (CL) Diedrich Klaus (DE) Di Renzo Gian Carlo (IT) Giudice Linda (US)* Gomel Victor (CA) Holzgreve Wolfang (CH) Khomasuridze Archil (GE) Klimek Rudolf (PL) Kovacs Gabor (AU) Kupesic Sanja (US)* Kurjak Asim (HR) Laufer Neri (IL) Naftolin Frederick (US) Patrizio Pasquale (US) Regan Lesley (GB)* Shoham Zeev (IL) Simoncini Tommaso (IT)* Strauss Jerome F. (US) Tan Lin Seang (CA) Taylor Hugh (US)* Trounson Alan (AU) Vartej Petrache (RO)

Honorary members * Elected in 2014 Arulkumaran Sabaratnam (GB)* Biran Affandi (ID) Bitzer Johannes (DE)* Bongso Ariff (SG) Brosens Ivo (BE)* Chervanek Frank (US)* Coutinho Elsimar (BR) Donnez Jacques (BE)* Driscoll Debra (US)* Fathalla Mahmoud (EG) Frydman Rene (FR) Gedis Grudzinskas (GB)* Hamberger Lars (SE) Jacobs Howard (GB) Jones Jr Howard (US) Mori Takahide (JP) Seppala Markku (FI) Simpson Joe Leigh (US)* Serour Gamal (EG)* Skouby Sven (DK)* Stuart Campbell (GB) Suzuki Shuetsu (JP) Wallach Edward (UD) Wei -Xiong L. (CN)

1st 1974 Rio de Janeiro, Brazil 2nd 1979 Tel Aviv, Israel 3rd 1981 Berlin, Germany 4th 1983 Bombay, India 5th 1985 Athens, Greece 6th 1987 Tokyo, Japan 7th 1990 Helsinki, Finland 8th 1993 Bali, Indonesia 9th 1996 Philadelphia, USA 10th 1999 Salvador, Brazil 11th 2002 Montreal, Canada 12th 2005 Venice, Italy 13th 2009 Venice, Italy 14th 2011 Melbourne, Australia 15th 2013 Venice, Italy

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Presentation | World Congress on Human Reproduction 2015

Female Reproductive System – KidsHealth

Unlike the male, the human female has a reproductive system located entirely in the pelvis. The external part of the female reproductive organs is called the vulva, which means covering. Located between the legs, the vulva covers the opening to the vagina and other reproductive organs located inside the body.

The fleshy area located just above the top of the vaginal opening is called the mons pubis. Two pairs of skin flaps called the labia (which means lips) surround the vaginal opening. The clitoris, a small sensory organ, is located toward the front of the vulva where the folds of the labia join. Between the labia are openings to the urethra (the canal that carries urine from the bladder to the outside of the body) and vagina. Once girls become sexually mature, the outer labia and the mons pubis are covered by pubic hair.

A female's internal reproductive organs are the vagina, uterus, fallopian tubes, and ovaries.

The vagina is a muscular, hollow tube that extends from the vaginal opening to the uterus. The vagina is about 3 to 5 inches (8 to 12 centimeters) long in a grown woman. Because it has muscular walls, it can expand and contract. This ability to become wider or narrower allows the vagina to accommodate something as slim as a tampon and as wide as a baby. The vagina's muscular walls are lined with mucous membranes, which keep it protected and moist.

The vagina serves three purposes:

A thin sheet of tissue with one or more holes in it called the hymen partially covers the opening of the vagina. Hymens are often different from female to female. Most women find their hymens have stretched or torn after their first sexual experience, and the hymen may bleed a little (this usually causes little, if any, pain). Some women who have had sex don't have much of a change in their hymens, though.

The vagina connects with the uterus, or womb, at the cervix (which means neck). The cervix has strong, thick walls. The opening of the cervix is very small (no wider than a straw), which is why a tampon can never get lost inside a girl's body. During childbirth, the cervix can expand to allow a baby to pass.

The uterus is shaped like an upside-down pear, with a thick lining and muscular walls in fact, the uterus contains some of the strongest muscles in the female body. These muscles are able to expand and contract to accommodate a growing fetus and then help push the baby out during labor. When a woman isn't pregnant, the uterus is only about 3 inches (7.5 centimeters) long and 2 inches (5 centimeters) wide.

At the upper corners of the uterus, the fallopian tubes connect the uterus to the ovaries. The ovaries are two oval-shaped organs that lie to the upper right and left of the uterus. They produce, store, and release eggs into the fallopian tubes in the process called ovulation. Each ovary measures about 1 to 2 inches (4 to 5 centimeters) in a grown woman.

There are two fallopian tubes, each attached to a side of the uterus. The fallopian tubes are about 4 inches (10 centimeters) long and about as wide as a piece of spaghetti. Within each tube is a tiny passageway no wider than a sewing needle. At the other end of each fallopian tube is a fringed area that looks like a funnel. This fringed area wraps around the ovary but doesn't completely attach to it. When an egg pops out of an ovary, it enters the fallopian tube. Once the egg is in the fallopian tube, tiny hairs in the tube's lining help push it down the narrow passageway toward the uterus.

The ovaries are also part of the endocrine system because they produce female sex hormones such as estrogen and progesterone.

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Female Reproductive System - KidsHealth

Center for Human Reproduction | Northwell Health, formerly …

The Center for Human Reproduction is the longest standing fertility center on Long Island and is a leader in reproductive and infertility medicine, as well as research into the reproductive sciences. The center is nationally respected for its high success rates and internationally recognized for its scientific achievements. The highly trained physicians are board-certified specialists in reproductive medicine.

The center is located on the Manhasset campus of North Shore University Hospital and is home to state-of-the-art procedure and recovery rooms, as well as the areas most advanced and secure andrology and embryology laboratories. The center provides complete clinical services, the most current surgical techniques, and the full spectrum of assisted reproduction technologies, including in-vitro fertilization (IVF), preimplantation genetic diagnosis (PGD) and a donor egg program, in a single, convenient location. The center also has office locations in Manhattan, Queens and throughout Long Island.

Learn more by watching the video below and visitingthe Center for Human Reproduction website.

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Center for Human Reproduction | Northwell Health, formerly ...

Human cloning – Wikipedia, the free encyclopedia

Human cloning is the creation of a genetically identical copy of a human. The term is generally used to refer to artificial human cloning, which is the reproduction of human cells and tissue. It does not refer to the natural conception and delivery of identical twins. The possibility of human cloning has raised controversies. These ethical concerns have prompted several nations to pass laws regarding human cloning and its legality.

Two commonly discussed types of theoretical human cloning are: therapeutic cloning and reproductive cloning. Therapeutic cloning would involve cloning cells from a human for use in medicine and transplants, and is an active area of research, but is not in medical practice anywhere in the world, as of 2015. Two common methods of therapeutic cloning that are being researched are somatic-cell nuclear transfer and, more recently, pluripotent stem cell induction. Reproductive cloning would involve making an entire cloned human, instead of just specific cells or tissues.

Although the possibility of cloning humans had been the subject of speculation for much of the twentieth century, scientists and policy makers began to take the prospect seriously in the 1960s.

Nobel Prize-winning geneticist Joshua Lederberg advocated cloning and genetic engineering in an article in The American Naturalist in 1966 and again, the following year, in The Washington Post.[1] He sparked a debate with conservative bioethicist Leon Kass, who wrote at the time that "the programmed reproduction of man will, in fact, dehumanize him." Another Nobel Laureate, James D. Watson, publicized the potential and the perils of cloning in his Atlantic Monthly essay, "Moving Toward the Clonal Man", in 1971.[2]

With the cloning of a sheep known as Dolly in 1996 by somatic cell nuclear transfer (SCNT), the idea of human cloning became a hot debate topic.[3] Many nations outlawed it, while a few scientists promised to make a clone within the next few years. The first hybrid human clone was created in November 1998, by Advanced Cell Technology. It was created using SCNT - a nucleus was taken from a man's leg cell and inserted into a cow's egg from which the nucleus had been removed, and the hybrid cell was cultured, and developed into an embryo. The embryo was destroyed after 12 days.[4]

In 2004 and 2005, Hwang Woo-suk, a professor at Seoul National University, published two separate articles in the journal Science claiming to have successfully harvested pluripotent, embryonic stem cells from a cloned human blastocyst using somatic-cell nuclear transfer techniques. Hwang claimed to have created eleven different patent-specific stem cell lines. This would have been the first major breakthrough in human cloning.[5] However, in 2006 Science retracted both of his articles on clear evidence that much of his data from the experiments was fabricated.[6]

On January 2008, Dr. Andrew French and Samuel Wood of the biotechnology company Stemagen announced that they successfully created the first five mature human embryos using SCNT. In this case, each embryo was created by taking a nucleus from a skin cell (donated by Wood and a colleague) and inserting it into a human egg from which the nucleus had been removed. The embyros were developed only to the blastocyst stage, at which point they were studied in processes that destroyed them. Members of the lab said that their next set of experiments would aim to generate embryonic stem cell lines; these are the "holy grail" that would be useful for therapeutic or reproductive cloning.[7][8]

In 2011, scientists at the New York Stem Cell Foundation announced that they had succeeded in generating embyronic stem cell lines, but their process involved leaving the oocyte's nucleus in place, resulting in triploid cells, which would not be useful for cloning.[10][11]

In 2013, a group of scientists led by Shoukhrat Mitalipov published the first report of embryonic stem cells created using SCNT. In this experiment, the researchers developed a protocol for using SCNT in human cells, which differs slightly from the one used in other organisms. Four embryonic stem cell lines from human fetal somatic cells were derived from those blastocysts. All four lines were derived using oocytes from the same donor, ensuring that all mitochondrial DNA inherited was identical. A year later, a team led by Robert Lanza at Advanced Cell Technology reported that they had replicated Mitalipov's results and further demonstrated the effectiveness by cloning adult cells using SCNT.[3][12]

In somatic cell nuclear transfer ("SCNT"), the nucleus of a somatic cell is taken from a donor and transplanted into a host egg cell, which had its own genetic material removed previously, making it an enucleated egg. After the donor somatic cell genetic material is transferred into the host oocyte with a micropipette, the somatic cell genetic material is fused with the egg using an electric current. Once the two cells have fused, the new cell can be permitted to grow in a surrogate or artificially.[13] This is the process that was used to successfully clone Dolly the sheep (see section on History in this article).[3]

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Human cloning - Wikipedia, the free encyclopedia

Human reproductive system – Wikipedia, the free encyclopedia

The human reproductive system usually involves internal fertilization by sexual intercourse. During this process, the male inserts his erect penis into the female's vagina and ejaculates semen, which contains sperm. The sperm then travels through the vagina and cervix into the uterus or fallopian tubes for fertilization of the ovum. Upon successful fertilization and implantation, gestation of the fetus then occurs within the female's uterus for approximately nine months, this process is known as pregnancy in humans. Gestation ends with birth, the process of birth is known as labor. Labor consists of the muscles of the uterus contracting, the cervix dilating, and the baby passing out the vagina (the female genital organ). Human's babies and children are nearly helpless and require high levels of parental care for many years. One important type of parental care is the use of the mammary glands in the female breasts to nurse the baby.[1]

The female reproductive system has two functions: The first is to produce egg cells, and the second is to protect and nourish the offspring until birth. The male reproductive system has one function, and it is to produce and deposit sperm. Humans have a high level of sexual differentiation. In addition to differences in nearly every reproductive organ, numerous differences typically occur in secondary sexual characteristics.

The male reproductive system is a series of organs located outside of the body and around the pelvis region of a male that contribute towards the reproduction process. The primary direct function of the male reproductive system is to provide the male sperm for fertilization of the ovum.

The major reproductive organs of the male can be grouped into three categories. The first category is sperm production and storage. Production takes place in the testes which are housed in the temperature regulating scrotum, immature sperm then travel to the epididymis for development and storage. The second category are the ejaculatory fluid producing glands which include the seminal vesicles, prostate, and the vas deferens. The final category are those used for copulation, and deposition of the spermatozoa (sperm) within the male, these include the penis, urethra, vas deferens, and Cowper's gland.

Major secondary sexual characteristics includes: larger, more muscular stature, deepened voice, facial and body hair, broad shoulders, and development of an adam's apple. An important sexual hormone of males is androgen, and particularly testosterone.

The testes release a hormone that controls the development of sperm. This hormone is also responsible for the development of physical characteristics in men such as facial hair and a deep voice.

The human female reproductive system is a series of organs primarily located inside of the body and around the pelvic region of a female that contribute towards the reproductive process. The human female reproductive system contains three main parts: the vagina, which leads from the vulva, the vaginal opening, to the uterus; the uterus, which holds the developing fetus; and the ovaries, which produce the female's ova. The breasts are involved during the parenting stage of reproduction, but in most classifications they are not considered to be part of the female reproductive system.

The vagina meets the outside at the vulva, which also includes the labia, clitoris and urethra; during intercourse this area is lubricated by mucus secreted by the Bartholin's glands. The vagina is attached to the uterus through the cervix, while the uterus is attached to the ovaries via the fallopian tubes. Each ovary contains hundreds of egg cells or ova (singular ovum).

Approximately every 28 days, the pituitary gland releases a hormone that stimulates some of the ova to develop and grow. One ovum is released and it passes through the fallopian tube into the uterus. Hormones produced by the ovaries prepare the uterus to receive the ovum. The lining of the uterus, called the endometrium, and unfertilized ova are shed each cycle through the process of menstruation. If the ovum is fertilized by sperm, it attaches to the endometrium and the fetus develops.

The development of the reproductive system and urinary systems are closely tied in the development of the human fetus. Despite the differences between the adult male and female reproductive system, there are a number of homologous structures shared between them due to their common origins within the fetus. Both organ systems are derived from the intermediate mesoderm. The three main fetal precursors of the reproductive organs are the Wolffian duct, Mllerian ducts, and the gonad. Endocrine hormones are a well known and critical controlling factor in the normal differentiation of the reproductive system.[2]

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Human reproductive system - Wikipedia, the free encyclopedia

Best IVF Centre indian, Best centre for IVF | surrogacy cost in india – Video


Best IVF Centre indian, Best centre for IVF | surrogacy cost in india
VFS Centre For Human Reproduction, an ISO 9001-2008 certified ART Centre offers a comprehensive range of infertility services under one roof and we are known for our innovation, integrity,...

By: Centre of Human Reproduction

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Best IVF Centre indian, Best centre for IVF | surrogacy cost in india - Video

What you need to know about Coronavirus and pregnancy in Ireland – RSVP Live

As if Pregnant women didn't have enough to worry about, many are now facing into added stress and uncertainity due to the coronavirus.

Since the first outbreak in China, the information available to pregnant women on how the virus affects unborn babies or whether mams-to-be are more susceptible to catching it in the first place, has been extremely limited.

So what do you need to know? The health experts are still unclear as to how exactly COVID-19 affects pregnant women and their babies.

One of the biggest risks of the virus according to the HSE is a High temperature, they explain: "One of the symptoms of coronavirus is fever (high temperature). This can increase the risk of complications during the first trimester (week 0 to 13)."

They urge pregnant women if you have a high temperature and you are pregnant, phone your GP or midwife.

When you are pregnant, your body naturally weakens your immune system. This is to help your pregnancy continue successfully. It means that when you are pregnant you may pick up infections more easily.

All pregnant women should get the flu vaccine. This will protect you and your baby from the flu, not from coronavirus.

The HSE advise that if you have coronavirus, there are extra precautions they will need to take before, during and after your baby's birth. Your obstetrician or midwife should talk to you about the safest way and time for your baby to be born.

Other expert doctors may also be involved in your care. These might include a doctor who specialises in infectious diseases and a neonatologist. This is a doctor who specialises in the care of newborn babies.

You may be in an isolation room with en-suite facilities during labour. You may need to stay in this room throughout your hospital stay.

You will not have to wear a facemask during labour and birth. But you will need to wear a surgical mask when youre outside your room.

Other than your doctor or midwife, only one other person may stay with you for the delivery. This could be a partner or family member. They will need to wear protective equipment to minimise the risk of infection.

If you have coronavirus, your doctor or midwife will discuss your options for after your baby is born.

One option may be to arrange for someone else to care for your baby while you wait for coronavirus to pass. This is to protect your baby from catching the virus.

A family member or a healthcare worker can provide this care. This could be provided at home or in the hospital. How long this lasts for will vary. The advice will depend on your symptoms and the results of any tests you have had.

If you choose to care for your baby after the birth, your doctor or midwife will explain the risk.

You and your baby will then be isolated in a single room with an en-suite bathroom. Your baby will be in an enclosed incubator in your room. An incubator is a special crib made of plastic, it keeps your baby warm. You will be able to see your baby in the incubator.

When your baby is outside the incubator for breastfeeding, bathing or caring you will need to:

Your baby should be observed for signs of infection. This will be for at least 14 days after the last contact with you. If your baby develops any signs of infection, they will need to be tested.

You will be advised about how many visitors you and your baby can have. In some cases, this might be just you and your partner. All visitors will need to wear protective equipment to wear.

If you have coronavirus and you are caring for your baby, you will be encouraged to breastfeed as normal.

You may decide to express breast milk so that someone else can feed your baby. This is usually your partner or a close family member. You might do this if you feel too unwell to breastfeed. Your healthcare team may also advise you that this is the safest way to feed your baby.

If you breastfeed

According to the European Society of Human Reproduction and Embryology there is no strong evidence of any negative effects of Covid-19 infection on pregnancies, especially those at early stages.

There are a few reported cases of women positive for Covid-19 who delivered healthy infants free of the disease.

However, they add that some of medical treatment given to severely infected patients may indicate the use of drugs which are contraindicated in pregnant women.

Therefore as a precautionary measure they advise all fertility patients considering or planning treatment should avoid becoming pregnant at this time.

For those patients already having treatment, they suggest considering deferred pregnancy or embryo freezing for later embryo transfer.

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What you need to know about Coronavirus and pregnancy in Ireland - RSVP Live

US Scientists Just Edited a Human Embryo for the First Time. (Yes, People Are Freaking Out.) – Mother Jones

US Scientists Just Edited a Human Embryo for the First Time. (Yes, People Are Freaking Out.)Ben Birchall/Associated Press

For the first known time in the United States, scientists used a gene-editing technique called CRISPR to modify early-stage human embryos, according to a report published Wednesday in MIT Technology Review.

Since the development several years ago ofCRISPR, a tool that allows scientists to change sequences of DNA within a cell, scientists have speculated about its potential to free families of genetic disease or stop the spread of other diseases like malaria, among other possibilities. But the technology also raises major ethical questions.

Heres a quick rundown of the latest breakthroughand how it could change the way we think about humanreproduction and, well, humans themselves.

How did the experiment work?

According to MIT Technology Reviews report, a team of researchers at Oregon Health & Science University, led by geneticist Shoukhrat Mitalipov, used CRISPR to correct disease-causing genes in human embryos. Its not yet clear whether these were viable embryosembryos that could, theoretically, grow into humans.

A wide range of diseaseslike Huntingtons, sickle-cell anemia, and Tay-Sachs, for exampleare caused by mutations in genes. Its also not clear what genes Mitalipov and his team edited in their experiment. But regardless, it appears that their study was successful in a couple ways: First, they reportedly edited a greater number of embryos than scientists had in previous studies. Second, Mitalipov and his team claim they did so without causing as manyerrors as previous scientists.

CRISPR has been used to edit human embryos a few times before; Chinese scientists did it in March. But in prior experiments, scientists ran into problems when CRISPR edits were taken up only by some of the cells in an embryo. This is called mosaicism:it means that the child that develops from the embryo could still inherit the disease that scientists tried to edit away.

According to MITs report, Mitalipov reduced the occurrence of mosaicism and seemed to largely avoid off-target edits (another kind of CRISPR error, wherein scientists accidentally alter a gene other than the one they aim to change).

Why is this important?

A couple reasons. First, its the only known attempt to use CRISPR to edit human embryos in the United States. More on the legality of that below.

Second, if this attempt really was successful, its big news for people whose families carry genetic disease. In theory, using this technique, scientists could edit not just our offspring, but our offsprings offspring. This is called human germline editing. When scientists edit the DNA in an embryo, the changes will theoretically be inherited by each successive generation, permanently fixing the germlinethe genetic inheritanceof a family.

This seems ethically complex.

Right. The ethics and laws surrounding human germline editingare murky. Scientists in favor of human germlinemodification often argue that the techniquewill help us reduce the occurrence of genetic diseases.

But criticsdisagree.This is just not needed for preventing inheritable disease, said Marcy Darnovsky, Executive Director of the Center for Genetics and Society. There are [other techniques that] can already be used safely to prevent the births of children with serious genetic diseases in almost every case. One example of such a technique is preimplantation diagnosis, commonly referred to as PGD, which allows parents to screen embryos for certain disease-causing genes before implanting them through in vitro fertilization (IVF). But its not always effectiveif someone carries two copies of a defective gene, for example, all their embryos would carry that gene, as well.

Darnovsky also worries about safety. Despite whatever the claims are about safety, [like] no mosaicism, we still dont know if that would mean its safe to create a new human being and anyone who tried it would be taking an enormous and unacceptable risk with that future persons life.

Another concern: Right now, scientists aresupposed to stick to editing disease-causing genes. But the technology opens up the possibility of editing genes for enhancementallowing parents to edit for certain kinds of physical and behavioral characteristics in their children. Darnovsky worries that this would usher in an era of genetic discrimination. That would be layering new forms of inequality and discrimination onto the ones we already live with, she said.

Is this legal?

Probably.In 2015, Congress passed a law forbidding the Food and Drug Administration from reviewing applications for germline editing of human embryos, meaning no clinical trials can move forward with FDA funding. We dont yet knowhow Mitalipov funded his project, but assuming it was funded privately, its perfectly legal.

That wouldnt be the case in many other countries. The Center for Genetics and Society reports that over 40 countries, including most with established biotech sectors, have established legal prohibitions on germline modification for human reproduction. An international treaty also prohibits it. The United States has no such policy.

Whats next?

Well know more once the study is released, but its worth noting that in February of this year, the National Academy of Sciences and the National Academy published a report that said human germline editing could be permitted in the future. It outlined criteria for germline editing, recommending that it only be used for disease prevention. The authors of the report wrote that editing for the enhancement of human traits and capacities should not be allowed at this time. But the report didnt eliminate the possibility of editing for enhancement in the future.

Reactions to the report were mixed. Some experts, like Darnovsky, feel that human germline modification should not be done for any purpose. But in an interview with Science, Eric Lander, president and founding director of MIT and Harvards Broad Institute, a genomics research center, said he thought the report struck the right balance of optimism and caution. They want to put friction tape on the slope so the slope isnt slippery, Lander said. Whether and for how long the tape will hold is an open question.

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US Scientists Just Edited a Human Embryo for the First Time. (Yes, People Are Freaking Out.) - Mother Jones

2020 could see an end to safe, legal abortion anywhere in America – The Guardian

If you care about the rights of women to make their own reproductive choices, 2020 is the year that matters.

Its too late to do anything about the current makeup of the court except, of course, for women and the people who love them to be very, very loud in our support of abortion rights, and signal that there will be a serious cost if the court overturns or scales back Roe.

But abortion rights supporters need to understand that the anti-abortion movement will not be content to simply overturn Roe. Nor will they be content with what they say is their goal to let the states decide. They will campaign not just at a state level but at a federal one to outlaw abortion wholesale in the United States.

This is the very real threat of 2020: Not just the end of Roe, which itself would be catastrophic, but an end to safe, legal abortion anywhere in the United States of America.

Democratic candidates, and voters, must face this threat head-on.

That means, yes, expecting that a Democratic president will do as Trump has done and appoint as many federal judges as possible the younger the better. If Roe is overturned, it will throw state abortion laws into chaos, and lawsuits over abortion rights (and abortion restrictions) will proliferate. Federal appeals courts will have the final say in most of these cases. Good judges who are not rightwing ideologues will be crucial to retain any semblance of basic human rights for women.

It also means a president who understands abortion rights are not safe in the courts alone, and require proactive protective measures. A federal law enshrining the right of all women to make intimate decisions about reproduction, including a right to abortion and contraception, is more necessary than ever.

Refreshingly, several Democratic candidates, including Elizabeth Warren, Cory Booker, Pete Buttigieg and Bernie Sanders, support such a law. Kamala Harris has even suggested an abortion rights version of the Voting Rights Act, requiring states with a history of misogynist anti-abortion laws to get federal approval before they are permitted to enact new abortion restrictions.

That codifying abortion rights into federal law is no longer a fringe Democratic position is a testament to the good work of abortion rights groups, who have spent decades pushing politicians to be proactive on abortion, not just reactive to restrictions. But offering rhetorical support for a position is easy. One question pro-choice voters should ask all candidates: is protecting reproductive freedom a very top priority?

There is a long list of other ideas progressive Democratic candidates should be putting on their agendas. Repealing the Hyde amendment, which restricts federal Medicaid dollars from paying for elective abortions, has already been embraced if not prioritized by most of the Democratic field. They should all pledge to repeal the Helms amendment, too, which places similar restrictions on US dollars spent on health and development overseas. A Democratic president should push Congress to permanently repeal the Global Gag Rule, which restricts not just abortion but even speech about abortion outside of US borders.

The US also lags in access to abortion medication, thanks to a spate of state restrictions; a federal abortion rights law should address that, too, and offer protections for women who self-induce their own abortions because they dont have access to a safe, legal, affordable option. Abortions are also largely relegated to clinics because many hospitals wont perform them. Any hospital that receives federal funds should be required to offer patients a full slate of reproductive healthcare, including contraception, emergency contraception and abortion. Insurance companies, too, should be required to fully cover abortion and contraception and if the leftiest of Democratic candidates wins and their universal healthcare plans come to fruition, abortion must be treated like any other medical procedure and covered accordingly.

If Donald Trump (or any Republican) wins in 2020, it could signal the end of abortion rights as we know it. Its more crucial than ever to have a Democrat in office who wont just pay the usual lip service to womens rights, but prioritize and push forward a plan to secure abortion access for all American women no matter what the supreme court does.

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2020 could see an end to safe, legal abortion anywhere in America - The Guardian