01.06.2012 - (idw) Ruprecht-Karls-Universitt Heidelberg

How do cells respond to damage and how are disturbances in cellular equilibrium avoided or compensated? These issues are at the heart of a new Collaborative Research Centre funded by the German Research Foundation (DFG) and ready to be launched at Heidelberg University on 1 July 2012. The CRC 1036 Cellular Quality Control and Damage Response is coordinated by Prof. Dr. Bernd Bukau, director of the Center for Molecular Biology of Heidelberg University (ZMBH). In the course of the next four years, this new research venture will receive funding to the tune of over ten million Euros. Press Release Heidelberg, 1 June 2012

New Collaborative Research Centre in Molecular Biology DFG provides over ten million Euros to fund CRC Cellular Quality Control and Damage Response

How do cells respond to damage and how are disturbances in cellular equilibrium avoided or compensated? These issues are at the heart of a new Collaborative Research Centre funded by the German Research Foundation (DFG) and ready to be launched at Heidelberg University on 1 July 2012. The CRC 1036 Cellular Quality Control and Damage Response is coordinated by Prof. Dr. Bernd Bukau, director of the Center for Molecular Biology of Heidelberg University (ZMBH). In the course of the next four years, this new research venture will receive funding to the tune of over ten million Euros.

The 17 research projects constituting CRC 1036 focus on the molecular mechanisms of cellular quality control. Despite their complexity, biological processes normally function with incredible precision, says Prof. Bukau. Nevertheless, the underlying processes are subject to occasional errors aggravated by external chemical or physical stress factors. In response to these mishaps, the cells of all organisms have developed efficient networks of surveillance systems operating at the levels of macromolecules, cellular compartments, cells and organs. These networks minimise and reverse damage caused by process deficiencies and defective molecules, Prof. Bukau adds.

At present, Heidelberg University receives funding for eight Collaborative Research Centres. In addition, there are five CRC/Transregio with key Heidelberg participation, four of them with coordinators from the university. Alongside CRC 1036, the German Research Foundation has also approved the establishment of CRC/TRR 125 Cognition-Guided Surgery starting up on 1 July 2012. Coordinator is the Heidelberg medical scientist Prof. Dr. Markus W. Bchler.

Contact Prof. Dr. Bernd Bukau Center for Molecular Biology of Heidelberg University (ZMBH) Phone: +49 6221 54-6850 direktor@zmbh.uni-heidelberg.de

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New Collaborative Research Centre in Molecular Biology