OverviewCaused by exposure to chemicals like asbestos, mesothelioma affects the tissue that covers your organs.What is mesothelioma?
Mesothelioma refers to tumors that develop in the mesothelium, a type of tissue that makes up the lining of cavities or hollows that protect and surround certain organs. This tissue forms:
Most people think of cancer of the pleura when they hear the word mesothelioma. This type of mesothelioma is related to exposure to asbestos and is often cancerous.
There are different ways to refer to mesothelioma. One way is to determine if the tumor is cancerous (malignant mesothelioma) or not cancerous (benign mesothelioma). Other types refer back to the cavities formed by mesothelial tissue and are called:
Mesothelioma may also be divided into groups based on the type of cell that creates the tumor. These types are:
Mesothelioma is associated with exposure to asbestos, a naturally occurring mineral used in many industries. Its use is now regulated in the U.S. and safety measures are in place, but this hasnt always been true. People who were exposed 20 to 40 years ago are only now being diagnosed.
More men than women are affected by mesothelioma, at a rate of 3 to 1. Men in their 50s to their 70s represent most of the diagnoses.
Workers in the following industries were, and possibly still are, more at risk due to increased exposure to asbestos products:
Military veterans may have been exposed in many ways at military bases, on ships and in construction.
In childhood mesothelioma, asbestos doesnt seem to be an issue. Children who have had earlier types of cancer and have been treated with radiation therapy have a higher risk of developing mesothelioma.
Mesothelioma is considered a rare illness. Currently, there are an estimated 3,000 to 4,000 new cases of mesothelioma in the U.S. each year. Of the total, there are about 2,500 cases of malignant pleural mesothelioma.
You can have mesothelioma without symptoms, and you can have different symptoms depending on the type of mesothelioma you have. If you have any of the types of mesothelioma, its possible to have:
In adults, the main cause of mesothelioma is past exposure to asbestos fibers and dust. Between 70% and 80% of people with mesothelioma were exposed to asbestos, mostly through work. It takes over 20 years for symptoms to develop.
In smaller numbers, people have developed mesothelioma after exposure to similar minerals like silica and erionite. Erionite is a type of mineral (zeolite) thats been linked to mesothelioma.
Scientists are also investigating whether your genes contribute to your risk of developing mesothelioma. This is because only a small number of people who have been exposed to asbestos have developed mesothelioma.
Scientists are also looking into other causes, including exposure to chemicals, having viral infections and having radiation. Additionally, radiation therapy is associated with childhood mesothelioma.
Your healthcare provider will take your medical history and do a physical examination. Hearing your symptoms and listening to your chest will provide the first clues. Your provider will probably order a series of tests to make their diagnosis. These tests may include:
Treating mesothelioma depends on what type you have. Treatment is different for benign (noncancerous) mesothelioma than it is for malignant mesothelioma.
Benign mesothelioma tumors arent cancerous and dont spread (metastasize) to other parts of your body. They can grow in the pleura, in your abdomen and in the reproductive organs of men and women. Typically, your healthcare provider will remove them in a surgical procedure. They usually dont come back if they are completely removed. Some providers might suggest further treatment with chemotherapy in the case of some types of benign mesothelioma.
After youve been diagnosed with mesothelioma, your healthcare provider will use the information they have to assess how far the disease has progressed. This assessment is called staging and refers to cancers. Higher staging numbers typically mean that the disease has progressed, such as Stage III or Stage IV disease.
The most common type of cancerous mesothelioma is malignant pleural mesothelioma. But for all types of malignant mesothelioma, your options may include surgery, with or without chemotherapy or other therapies, or chemotherapy, radiation therapy and other types of therapy without surgery.
If your provider stages your tumor and youre able to have surgery, youll have surgery to remove the tumor. However, less than 33% of people with malignant pleural mesothelioma can have this type of surgery. You may or may not have chemotherapy or radiation therapy as well.
If you cant have surgery, the tumor is treated with chemotherapy and/or radiation. You may have an option to try treatments that are being studied, such as biologic agents and antiangiogenic therapies. Antiangiogenic treatments try to destroy cancer by making sure it doesnt have a blood supply.
Even though surgery and chemotherapy might be the best course of treatment, they may have complications such as:
The best way to prevent mesothelioma is to avoid asbestos and other harmful minerals. If you must be around asbestos, be sure to follow the guidelines for protective masks and clothing.
The prognosis for any type of malignant mesothelioma is poor. Many people die in the first four to six months after diagnosis and most by 12 months after diagnosis. However, some people have lived longer than that and a rare few were alive at the five-year mark.
If youve been treated for malignant melanoma, your mesothelioma specialist will probably want to see you on a specific schedule. Youll also want to see your primary care provider too. These providers will monitor your overall health and may do tests to see if cancer returns.
Ask, too, about ways to improve your life if you're having side effects of chemotherapy and radiation. There may be more options than you think.
Make sure that you know when you should contact a healthcare provider immediately for instance, if you have a fever or extreme dizziness. Then, follow those suggestions. Its always OK to contact your provider with any questions you might have.
Benign mesothelioma, or mesothelioma that isnt cancerous, isnt fatal. However, malignant mesothelioma is almost always fatal.
Part of the reason that malignant mesothelioma is so deadly is that it grows without symptoms for years. Another reason is that current treatment options arent that successful at treating the disease.
There are many different types of mesothelioma, so life expectancy estimates vary. And people are all different in terms of age, general health and other medical conditions. As always, youll probably have better results if mesothelioma is found early and treated as vigorously as possible.
A note from Cleveland Clinic
If you are someone who used to work with asbestos and you have trouble breathing, make the call to your healthcare provider to get checked out. If you do find out you have mesothelioma, work with your healthcare team to develop a plan for each type of possible outcome. This can mean getting as much information as you can and speaking to family and friends about whats going on. You might find it useful to join a support group or get some counseling. You might want to be involved in clinical studies if you can. Your healthcare team will provide support and information.
Read more from the original source:
Mesothelioma: Types, Causes, Symptoms & Treatment - Cleveland Clinic
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- Republican Health Care Bill Includes Asbestos Exposure Funding for Libby Residents - Mesothelioma.com - March 24th, 2017 [March 24th, 2017]
- Pembrolizumab shows promise in treatment of mesothelioma - Science Daily - March 24th, 2017 [March 24th, 2017]
- Veterans with Mesothelioma Benefit from Telephone Triage - Asbestos.com - March 24th, 2017 [March 24th, 2017]
- Mesothelioma Survival Rates Slowly Improving - Mesothelioma.net Blog (blog) - March 24th, 2017 [March 24th, 2017]
- Understanding Mesothelioma Caregiver Styles - Asbestos.com (blog) - March 24th, 2017 [March 24th, 2017]
- Mesothelioma Patients Turn to Cannabis - AlterNet - March 24th, 2017 [March 24th, 2017]
- Mesothelioma | Overview, Treatment Options and Survivor Stories - March 24th, 2017 [March 24th, 2017]
- Accelerated Approval Granted to Drug in Mesothelioma Research Pipeline - MesotheliomaHelp.org (blog) - April 8th, 2017 [April 8th, 2017]
- New Study Affirms Mesothelioma Survival Benefit with Post-Surgical IMRT, According to Surviving Mesothelioma - Benzinga - April 8th, 2017 [April 8th, 2017]
- The Key to Mesothelioma Treatment Success with Immunotherapy - Surviving Mesothelioma - April 8th, 2017 [April 8th, 2017]
- New Evidence Supports Post-Surgical IMRT for Mesothelioma Treatment - Surviving Mesothelioma - April 8th, 2017 [April 8th, 2017]
- Shorter Mesothelioma Survival Linked to High Platelet Count - Asbestos.com - April 8th, 2017 [April 8th, 2017]
- Mesothelioma Victims Center Now Appeals to All Diagnosed ... - Yahoo Finance - April 8th, 2017 [April 8th, 2017]
- Early research suggests first immunotherapy for mesothelioma on the horizon - Medical Xpress - June 6th, 2017 [June 6th, 2017]
- Bristol-Myers Squibb's Opdivo, Yervoy put the brakes on mesothelioma in phase 2 - FiercePharma - June 6th, 2017 [June 6th, 2017]
- Methanol from African Plants Kills Mesothelioma Cells - Asbestos.com - June 6th, 2017 [June 6th, 2017]
- Mesothelioma Patients to be Celebrated on National Cancer Survivor's Day - Mesothelioma.net Blog (blog) - June 6th, 2017 [June 6th, 2017]
- IO Strategy In Mesothelioma Finally Gets Mapped Out | Seeking Alpha - Seeking Alpha - June 6th, 2017 [June 6th, 2017]
- New Blood Test Could Mean Earlier Mesothelioma Diagnosis - Surviving Mesothelioma - June 6th, 2017 [June 6th, 2017]
- Using Viruses to Boost Mesothelioma Immunotherapy - Asbestos.com - June 6th, 2017 [June 6th, 2017]
- Resilience Can Help Mesothelioma Patients and Their Families ... - MesotheliomaHelp.org (blog) - June 7th, 2017 [June 7th, 2017]
- Janet Stanton Schnitzer Remembers Her Father's Mesothelioma Battle - Mesothelioma & Asbestos Awareness Center (blog) - June 7th, 2017 [June 7th, 2017]
- Treating Mesothelioma: A rare, aggressive caner - ABC2 News - June 7th, 2017 [June 7th, 2017]
- Asbestos and Mesothelioma Lawsuits: What to Expect | Nolo.com - June 7th, 2017 [June 7th, 2017]
- Mesothelioma Victims Center Now Urges a Roofer/Insulator With Mesothelioma to Call About Why It Is Necessary to ... - PR Newswire (press release) - June 9th, 2017 [June 9th, 2017]
- Mesothelioma Patients May Have Another Treatment Option With FDA Expanded-Use Approval of Lung Cancer Drug - MesotheliomaHelp.org (blog) - June 9th, 2017 [June 9th, 2017]
- A Breath Test for Mesothelioma? - Surviving Mesothelioma - June 9th, 2017 [June 9th, 2017]
- Mesothelioma Cancer: 12 Essential Facts - Asbestos News - June 9th, 2017 [June 9th, 2017]
- Mesothelioma - NHS Choices - June 9th, 2017 [June 9th, 2017]
- 15-year Mesothelioma Survivor Living Life By Design - Asbestos.com (blog) - June 9th, 2017 [June 9th, 2017]
- Mesothelioma Cancer Overview | Experienced Lawyers Here to Help - June 11th, 2017 [June 11th, 2017]
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- Mesothelioma Patients Can See Improved Survival By Reporting Side Effects - MesotheliomaHelp.org (blog) - June 12th, 2017 [June 12th, 2017]
- What is Mesothelioma? | Surviving Mesothelioma - Surviving Mesothelioma - June 13th, 2017 [June 13th, 2017]
- Cases of Pleural Mesothelioma - Surviving Mesothelioma - June 13th, 2017 [June 13th, 2017]
- The Importance of Cancer Research in Immunotherapy - Mesothelioma.com (blog) - June 14th, 2017 [June 14th, 2017]
- Hopes High for Mesothelioma Immunotherapy Treatment ... - Mesothelioma.net Blog (blog) - June 14th, 2017 [June 14th, 2017]
- Asbestos Sprayers Face Higher Lifetime Mesothelioma Risk ... - Surviving Mesothelioma - June 14th, 2017 [June 14th, 2017]
- Remembering Loved Ones Lost to Mesothelioma, Looking Forward to Progress in Treatment - MesotheliomaHelp.org (blog) - June 14th, 2017 [June 14th, 2017]
- Chicago Public Schools Ignoring Asbestos Problem - Mesothelioma.com - June 16th, 2017 [June 16th, 2017]
- Length of Time Between Surgeries a Marker for Mesothelioma Survival - Surviving Mesothelioma - June 16th, 2017 [June 16th, 2017]
- Mesothelioma Survivor Deals with Pain 15 Years After Surgery - Asbestos.com (blog) - June 16th, 2017 [June 16th, 2017]
- Nivolumab and Ipillimumab Show Promise in Treating Mesothelioma Recurrence - Mesothelioma.com - June 16th, 2017 [June 16th, 2017]
- Mesothelioma Patients Should Heed FDA Warnings Regarding Miracle Cures - MesotheliomaHelp.org (blog) - June 16th, 2017 [June 16th, 2017]
- Mesothelioma Patients May Benefit from Marijuana Research - Mesothelioma.net Blog (blog) - June 17th, 2017 [June 17th, 2017]
- The Challenges of Research in Immunotherapy - Mesothelioma.com (blog) - June 17th, 2017 [June 17th, 2017]
- Despite Mesothelioma Diagnosis, Dad Loved Father's Day - Asbestos.com (blog) - June 17th, 2017 [June 17th, 2017]
- I Want to Keep Writing About Mesothelioma and My Family's Journey Because It Matters - MesotheliomaHelp.org (blog) - June 17th, 2017 [June 17th, 2017]
- Mesothelioma Clinical Trial Opens with High Expectations - Asbestos.com - June 17th, 2017 [June 17th, 2017]
- Cediranib May be Safe Supplement to Mesothelioma Treatment - Surviving Mesothelioma - June 17th, 2017 [June 17th, 2017]
- New Trial Finds VEGF-Inhibitor May Safely Boost Mesothelioma ... - Benzinga - June 18th, 2017 [June 18th, 2017]
- Mesothelioma Symptoms - Identify Early Warning Signs - June 18th, 2017 [June 18th, 2017]
- Mesothelioma Victims Center Now Urges a Diagnosed Construction Worker or Plumber to Call for Instant Access to the ... - PR Newswire (press release) - June 20th, 2017 [June 20th, 2017]
- Mesothelioma Treatment May Benefit From New Discovery ... - Mesothelioma.net Blog (blog) - June 20th, 2017 [June 20th, 2017]
- The Influence of BAP1 on Mesothelioma Survival - Surviving Mesothelioma - June 20th, 2017 [June 20th, 2017]
- Clinical Trial to Assess If Radiation Therapy Can Bring Effective Relief from Mesothelioma Pain - MesotheliomaHelp.org (blog) - June 20th, 2017 [June 20th, 2017]
- Asbestos Exposure Attorneys - Mesothelioma Lawsuits ... - June 20th, 2017 [June 20th, 2017]
- Can a Breath Test Diagnose Mesothelioma in the Early Stages? - Asbestos.com - June 21st, 2017 [June 21st, 2017]
- Mesothelioma Compensation Center Now Urges an Electric Utility Worker or Electrician with Mesothelioma to Aim High ... - PR Newswire (press release) - June 21st, 2017 [June 21st, 2017]
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- 5 Questions: Treatment options exist for mesothelioma - Las Vegas Review-Journal - June 21st, 2017 [June 21st, 2017]
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- Remembering Mesothelioma Victims in the UK - Mesothelioma.com (blog) - June 21st, 2017 [June 21st, 2017]
- Peritoneal Cancer Index: What it Means for Mesothelioma Patients - Mesothelioma & Asbestos Awareness Center (blog) - June 21st, 2017 [June 21st, 2017]
- Mesothelioma Risk Continues to Rise for Decades After Asbestos Exposure - Surviving Mesothelioma - June 21st, 2017 [June 21st, 2017]
- Nintedanib Combination Delayed Progression in Malignant Mesothelioma - Cancer Network - June 22nd, 2017 [June 22nd, 2017]
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- The Mesothelioma Victims Center Now Urges a Diagnosed Navy ... - PR Newswire (press release) - June 22nd, 2017 [June 22nd, 2017]
- Targeted Therapy May Soon be Primary Approach for Mesothelioma Treatment - MesotheliomaHelp.org (blog) - June 23rd, 2017 [June 23rd, 2017]
- Time Between Surgeries Helps Predict Mesothelioma Survival - Asbestos.com - June 23rd, 2017 [June 23rd, 2017]
- Testicular and Cardiac Mesothelioma - Surviving Mesothelioma - June 23rd, 2017 [June 23rd, 2017]
- Mesothelioma Veterans Center - Access Benefits & VA Claims - June 23rd, 2017 [June 23rd, 2017]
- Malignant Mesothelioma (Asbestos Cancer) > The Mesothelioma ... - June 23rd, 2017 [June 23rd, 2017]
- Mesothelioma Law Firm | Sokolove Law - June 23rd, 2017 [June 23rd, 2017]
- MicroRNAs May Be Key to Better Immunotherapy for Mesothelioma - Surviving Mesothelioma - June 24th, 2017 [June 24th, 2017]
- Mesothelioma Survival Rate | Factors Affecting Survivorship - June 24th, 2017 [June 24th, 2017]
- Scientists "Turn Off" Tumor-Protecting Protein in New Mesothelioma Study, According to Surviving Mesothelioma - Benzinga - June 26th, 2017 [June 26th, 2017]
- Symptoms of Mesothelioma - Critical Signs to Watch For - June 26th, 2017 [June 26th, 2017]