MADISON,WI(September 17, 2020) Robert Golden sees the danger of Alzheimers disease.

Among the 10 most deadly diseases [in America], he said, its the only one that cannot be prevented or cured at this time.

Golden is the dean of UWMadisons School of Medicine and Public Health, and he hosted a conversation about Alzheimers research during the Wisconsin Medicine Livestream event on September 15. Goldens guests included several of the UWs leading dementia researchers: Sanja Asthana, the founding director of the Wisconsin Alzheimers Disease Research Center; Sterling Johnson, the Finley Professor of Geriatrics and Dementia; Cynthia Carlsson, the Holland Professor of Alzheimers Disease; and Carey Gleason, a clinical neuropsychologist and member of the UW faculty.

Asthana noted that six million Americans suffer from Alzheimers and gave an overview of UW studies of the disease. He urged viewers to see the value of the universitys work. It is quite clear that the only way we can [beat] Alzheimers is through cutting-edge research, he said.

The key biomarker for Alzheimers is a buildup of amyloid proteins, and Johnson described efforts to increase doctors ability to recognize amyloid accumulations. Our goals are to identify Alzheimers before its symptoms appear, he said. You think of Alzheimers affecting the brain, and that means we have to get in and study the brain.

Carlsson added that amyloid isnt the only risk factor. Alzheimers also tends to show up more often in people who have high blood pressure, diabetes, poor sleep, traumatic brain injury, depression, and stress. The good news is these are things we can do something about, she said. She showed how a decrease in these other risk factors project to a 10 percent reduction of U.S. Alzheimers cases by 2050.

Gleason discussed recruitment for research projects, which have often drawn on an overrepresentation of white people, even though the prevalence of Alzheimers among Black and Native American populations is much higher. The UW has made a concerted effort to improve recruitment of underrepresented populations in its dementia studies, and the universitys success in this area is due to the way it has involved subjects as partners in the research process. We see them as true partners, she says, and not just bodies from which we collect data.

Golden brought forward questions from some of the hundreds of viewers who watched the event live on YouTube. To hear more from the members of the panel, view a recording of Wisconsin Medicine. The series is offered via YouTube and will continue into the fall. The next event will be September 29 and will cover the future of medicine.

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Wisconsin Medicine: Livestream on ending Alzheimers - Wisbusiness.com