Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 – Annals of Internal Medicine

University Medical Center Hamburg-Eppendorf, Hamburg, Germany (D.W., J.S., M.L., S.S., C.E., A.H., F.H., H.M., I.K., A.S.S., C.B., G.D., A.N., D.F., S.P., S.S., C.B., M.M.A., M.A., K.P., S.K.)

Asklepios Hospital Barmbek, Hamburg, Germany (H.B., A.S.)

Bethesda Hospital Bergedorf, Hamburg, Germany (H.B.)

Agaplesion Diakonie Hospital, Hamburg, Germany (A.D.)

Amalie Sieveking Hospital, Hamburg, Germany (H.P.)

Asklepios Hospital Saint Georg, Hamburg, Germany (S.S.)

Financial Support: Institutional Funds of University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Disclosures: Dr. Nierhaus reports grants and personal fees from CytoSorbents Europe and personal fees from Thermo Fisher Scientific and Biotest outside the submitted work. Dr. Frings reports personal fees from Xenios outside the submitted work. Dr. Bokemeyer reports personal fees from Sanofi-Aventis, Merck KgaA, Bristol-Myers Squibb, Merck Sharp & Dohme, Lilly ImClone, Bayer, GSO Contract Research, AOK Rheinland/Hamburg, and Novartis outside the submitted work. Dr. Kluge reports grants from Ambu, E.T. View, Fisher & Paykel, Pfizer, and Xenios and personal fees from Amomed, ArjoHuntleigh, Astellas, Astra, Basilea, Bard, Bayer, Baxter, Biotest, CSL Behring, CytoSorbents, Fresenius, Gilead, MSD, Orion, Pfizer, Philips, Sedana, Sorin, Xenios, and Zoll outside the submitted work. Authors not named here have disclosed no conflicts of interest. Disclosures can also be viewed at http://www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-2003.

Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that her spouse has stock options/holdings with Targeted Diagnostics and Therapeutics. Darren B. Taichman, MD, PhD, Executive Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Eliseo Guallar, MD, MPH, DrPH, Deputy Editor, Statistics, reports that he has no financial relationships or interests to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Christina C. Wee, MD, MPH, Deputy Editor, reports employment with Beth Israel Deaconess Medical Center. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Yu-Xiao Yang, MD, MSCE, Deputy Editor, reports that he has no financial relationships or interest to disclose.

Reproducible Research Statement: Study protocol: Available with approval through written agreement with Dr. Wichmann (e-mail, d.wichmann@uke.de). Statistical code: Available from Dr. Kluge (e-mail, s.kluge@uke.de). Data set: Not available.

Corresponding Author: Dominic Wichmann, MD, Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany; e-mail, d.wichmann@uke.de.

Current Author Addresses: Drs. Wichmann, Burdelski, de Heer, Nierhaus, Frings, and Kluge: Department of Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Drs. Sperhake, Edler, Heinemann, Heinrich, Mushumba, Kniep, Schrder, and Pschel: Department of Legal Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Drs. Ltgehetmann, Pfefferle, and Aepfelbacher: Institute of Medical Microbiology Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Dr. Steurer: Department of Pathology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Dr. Becker: Department of Pulmonology and Internal Intensive Care, Asklepios Hospital Barmbek, Rbenkamp 220, 22307 Hamburg, Germany.

Dr. Bredereke-Wiedling: Emergency Department, Bethesda Hospital Bergedorf, Glindersweg 80, 21029 Hamburg, Germany.

Dr. de Weerth: Department of Internal Medicine, Agaplesion Diakonie Hospital, Hohe Weide 17, 20259 Hamburg, Germany.

Dr. Paschen: Department of Anesthesiology and Intensive Care, Amalie Sieveking Hospital, Haselkamp 33, 22359 Hamburg, Germany.

Dr. Sheikhzadeh-Eggers: Emergency Department, Asklepios Hospital Saint Georg, Lohmhlenstrasse 5, 20099 Hamburg, Germany.

Dr. Stang: Department of Oncology, Asklepios Hospital Barmbek, Rbenkamp 220, 22307 Hamburg, Germany.

Drs. Schmiedel and Addo: Sections of Infectious Diseases and Tropical Medicine, Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Dr. Bokemeyer: Department of Hematology and Oncology, Section of Pneumology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246 Hamburg, Germany.

Author Contributions: Conception and design: D. Wichmann, J.P. Sperhake, F. Heinrich, S. Kluge.

Analysis and interpretation of the data: D. Wichmann, J.P. Sperhake, M. Ltgehetmann, S. Steurer, F. Heinrich, H. Mushumba, I. Kniep, A.S. Schrder, A. de Weerth, C. Bokemeyer, M.M. Addo, M. Aepfelbacher, S. Kluge.

Drafting of the article: D. Wichmann, J.P. Sperhake, M. Ltgehetmann, I. Kniep, S. Kluge.

Critical revision for important intellectual content: D. Wichmann, J.P. Sperhake, I. Kniep, C. Burdelski, G. de Heer, A. Nierhaus, A. de Weerth, A. Stang, S. Schmiedel, M.M. Addo, M. Aepfelbacher, S. Kluge.

Final approval of the article: D. Wichmann, J.P. Sperhake, M. Ltgehetmann, S. Steurer, C. Edler, A. Heinemann, F. Heinrich, H. Mushumba, I. Kniep, A.S. Schrder, C. Burdelski, G. de Heer, A. Nierhaus, D. Frings, S. Pfefferle, H. Becker, H. Bredereke-Wiedling, A. de Weerth, H. Paschen, S. Sheikhzadeh-Eggers, A. Stang, S. Schmiedel, C. Bokemeyer, M.M. Addo, M. Aepfelbacher, K. Pschel, S. Kluge.

Provision of study materials or patients: D. Wichmann, A. Heinemann, F. Heinrich, H. Mushumba, C. Burdelski, G. de Heer, A. deWeerth, S. Sheikhzadeh-Eggers, C. Bokemeyer, M.M. Addo, K. Pschel.

Statistical expertise: S. Kluge.

Obtaining of funding: M. Aepfelbacher.

Administrative, technical, or logistic support: D. Wichmann, J.P. Sperhake, S. Steurer, C. Edler, A. Heinemann, F. Heinrich, A.S. Schrder, C. Burdelski, M.M. Addo, S. Kluge.

Collection and assembly of data: D. Wichmann, J.P. Sperhake, M. Ltgehetmann, S. Steurer, C. Edler, F. Heinrich, H. Mushumba, I. Kniep, A.S. Schrder, G. de Heer, A. Nierhaus, D. Frings, S. Pfefferle, H. Becker, H. Bredereke-Wiedling, A. de Weerth, H.R. Paschen, A. Stang, S. Schmiedel, K. Pschel, S. Kluge.

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Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 - Annals of Internal Medicine

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