Longevity Global Inc. Now Launches New Range of Improved and Less Smoke Producing Power Generators

Longevity Global Inc. has recently made another revolutionary launch. This time the leading cutting and welding equipment manufacturing company has come up with their new range power generators. There new range includes some phenomenal models of silent diesel generators which are ideal to maintain peace in the environment. Also various other models of powerful yet small generators are amongst the new line product lines of Longevity.

Hayward, CA (PRWEB) October 10, 2012

All the technologically advanced range of generators are easy to install and user friendly in operation. Longevity Global Inc. now also offers cost effective natural gas generators which are highly efficient in fuel consumption compared to other traditional gas generators. It also has a lesser chance in being contaminated from the ground and from its surroundings. A traditional portable gas generator would need to fill it up with fuel. Gas portable generator is beneficial because it does not disperse a lot of fumes. Meanwhile a gas powered generator can as its engine runs. The fumes can smell and they are toxic. Their gas generators powered by natural gas does not at all smell. These generators come in several sizes. They range from the typical small generators to the larger ones meant to last for an extended period of time. Longevity provides generators as per requirements and budget.

For smooth and quiet operation all offered generators of Longevity Global Inc. are enclosed in a steel frame which is very rigid, insulated with sound proof material and isolated by motor mounts. Latest models of our LDG Silent Diesel Generators include full power panel with engine shut off switch, hour meter, voltage selector etc. The idle control feature of these generators saves fuel and reduces noise. Longevity backs its offered quality products with one year or 3000 Hour parts warranty. Wide range of power output of Longevity brand generators can meet all the power backup needs of both residence and business places. Along with the portable generators and higher power output generators of superlative quality offered by Longevity, many best in the class plasma cutters, TIG welders, MIG welders and other accessories at unparalleled price range are also offered at this company.

Longevity Global Inc. is providing dedicated service since 2001. It is growing at a phenomenal pace with high customer satisfaction, innovative products and efficient industrial production. It works in different parts of world with distributors in Canada, Mexico, Brazil, Australia, United Kingdom, and multiple other countries. Longevity Global Inc. serve globally with manufacturing facilities with its logistic companies to effectively distribute products in a punctual and effective manner.

To know more visit http://www.longevity-inc.com

Simon Katz Longevity, Inc. 1.877.566.4462 Email Information

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Longevity Global Inc. Now Launches New Range of Improved and Less Smoke Producing Power Generators

DNA leads to arrest in sexual assault of Santa Ana girl

A man was arrested Wednesday after he was linked through DNA to the sexual assault of an 8-year-old Santa Ana girl in her bunk bed, police said. The assailant climbed in through an unlocked window of her home.

Damien Anthony Reyes was arrested at his home in the 1300 block of North King Street after detectives were told there was a positive match on the DNA left at the scene of the June attack.

Reyes was booked at the Santa Ana Jail on suspicion of burglary, child molestation by force with enhancements that could lead to a potential life sentence upon conviction. He is being held in lieu of $1 million bail.

Authorities did not say how Reyes' DNA got into the state or federal DNA database. In most cases an arrest or conviction leads to a DNA sample being taken.

The noise woke up the girl's 13-year-old sister, who was asleep on the bottom bed, police said. Both girls screamed and woke up their father, who ran to their aid.

Detectives said the man immediately fled the house through the same window and was last seen running south.

Man found with body bags, smoke grenade at LAX investigated

Hazing probe launched after Fresno State fraternity pledge dies

-- Richard Winton

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DNA leads to arrest in sexual assault of Santa Ana girl

Posted in DNA

Dinos' DNA Demise: Genetic Material Has a 521-Year Half-Life

A new analysis confirms the widely held suspicion that DNA from dinosaurs and ancient insects trapped in amber cannot be recovered to make a 'Jurassic Park'-style theme park

By Matt Kaplan and Nature magazine

Palaeogeneticist Morten Allentoft used the bones of extinct moa birds to calculate the half-life of DNA. Image: M. Mhl

Showcasing more than fifty of the most provocative, original, and significant online essays from 2011, The Best Science Writing Online 2012 will change the way...

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From Nature magazine

Few researchers have given credence to claims that samples of dinosaur DNA have survived to the present day, but no one knew just how long it would take for genetic material to fall apart. Now, a study of fossils found in New Zealand is laying the matter to rest and putting paid to hopes of cloning a Tyrannosaurus rex.

After cell death, enzymes start to break down the bonds between the nucleotides that form the backbone of DNA, and micro-organisms speed the decay. In the long run, however, reactions with water are thought to be responsible for most bond degradation. Groundwater is almost ubiquitous, so DNA in buried bone samples should, in theory, degrade at a set rate.

Determining that rate has been difficult because it is rare to find large sets of DNA-containing fossils with which to make meaningful comparisons. To make matters worse, variable environmental conditions such as temperature, degree of microbial attack and oxygenation alter the speed of the decay process.

But palaeogeneticists led by Morten Allentoft at the University of Copenhagen and Michael Bunce at Murdoch University in Perth, Australia, examined 158 DNA-containing leg bones belonging to three species of extinct giant birds called moa. The bones, which were between 600 and 8,000 years old, had been recovered from three sites within 5 kilometres of each other, with nearly identical preservation conditions including a temperature of 13.1 C. The findings are published today in Proceedings of the Royal Society B.

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Dinos' DNA Demise: Genetic Material Has a 521-Year Half-Life

Posted in DNA

How long can DNA last? A million years

In "Jurassic Park," scientists extract 80-million-year-old dino DNA from the bellies of mosquitoes trapped in amber. Researchers may never be able to extract genetic material that old and bring a T. rex back to life, but a new study suggests DNA can survive in fossils longer than previously believed.

The oldest DNA samples ever recovered are from insects and plants in ice cores in Greenland up to 800,000 years old. But researchers had not been able to determine the oldest possible DNA they could get from the fossil record because DNA's rate of decay had remained a mystery.

Now scientists in Australia report they've been able to estimate this rate based on a comparison of DNA from 158 fossilized leg bones from three species of the moa, an extinct group of flightless birds that once lived in New Zealand. The bones date between 600 and 8,000 years old and importantly all come from the same region.

Science news from NBCNews.com

Although Einstein's theories suggest nothing can move faster than the speed of light, two scientists have extended his equations to show what would happen if faster-than-light travel were possible.

Temperatures, oxygenation and other environmental factors make it difficult to detect a basic rate of degradation, researcher Mike Bunce, from Murdoch University's Ancient DNA lab in Perth, explained in a statement.

"The moa bones however have allowed us to study the comparative DNA degradation because they come from different ages from a region where they have all experienced the same environmental conditions," Bunce said.

Based on this study, Bunce and his team put DNA's half-life at 521 years, meaning half of the DNA bonds would be broken down 521 years after death, and half of the remaining bonds would be decayed another 521 years after that, and so on. This rate is 400 times slower than simulation experiments predicted, the researchers said, and it would mean that under ideal conditions, all the DNA bonds would be completely destroyed in bone after about 6.8 million years.

"If the decay rate is accurate then we predict that DNA fragments of sufficient length will preserve in frozen fossil bone of around one million years in age," Bunce said.

But he cautioned that more research is needed to examine the other variables in the breakdown of DNA.

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How long can DNA last? A million years

Posted in DNA

DNA Brands to Re-Brand and Undertake New Marketing Campaign

BOCA RATON, FL--(Marketwire - Oct 10, 2012) - DNA Brands, Inc. ( OTCBB : DNAX ), makers of the great tasting DNA Energy Drink, a favorite of the action sports community and its enthusiastic followers, announced today it is re-branding its entire line of DNA Energy Drinks to be able to reach a greater portion of the ever-growing energy drink market.

Darren Marks, President of DNA Brand, Inc., stated, "The one comment we hear over and over is that energy drinks don't taste good. We were previously selected as the best tasting energy drink by an independent international World Beverage Competition. We intend to get this fact out to the energy drink consumer. Our current graphics were primarily geared to the action sports community. Although we will continue to pursue these same customers, we will do it with new and innovative products geared to better communicate the brand's core identity while appealing to a much broader demographic; active consumers from every walk of life. We are confident that this rebranding will enable us to better position ourselves in a category that continues to re-invent itself and grow at a rapid pace. Energy drink sales increased 17.2% in 2011, the highest growth rate since 2007." In conjunction with the re-branding, Jeff Jonke has been promoted to the Company's Executive Vice-President and General Manger. He will be the driving force behind this new and exciting time for DNA Brands, Inc.

About DNA Brands, Inc.

DNA BRANDS, makers of DNA Energy Drink, the award-winning, best-tasting energy drink at the 2010 World Beverage Competition, is a proprietary blend of quality ingredients in four flavors: Citrus, Lemon Lime, Sugar Free Citrus and CRANRAZBERRY. DNA can be found at independent retailers throughout the state of Florida, as well as national retailers including Walgreens, Race Trac and Circle K. Distribution is primarily through Grass Roots Beverage, the Company's wholly owned subsidiary and select Miller and Anheuser-Bush distributors in select markets.

DNA is a proud sponsor of many action sport teams. True to its action sports roots, DNA BRANDS, INC. has earned national recognition through its sponsorship of the DNA Energy Drink/Jeff Ward Racing team where it competes on a world-class level in Supercross and Motocross, reaching millions of fans. DNA Energy Drink can also be found in other action sports such as Surfing, BMX, Wakeboarding and Skateboarding and its athletes are recognized stars in their own right.

For more information about DNA Energy Drink, its athletes and sponsorships, please visit http://www.dnabrandsusa.com or contact: Darren M. Marks, President (954) 970 3826 darren@dnaenergydrink.com

Safe Harbor Forward-Looking Statements

To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company's development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made.

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DNA Brands to Re-Brand and Undertake New Marketing Campaign

Posted in DNA

'Jurassic Park' May Be Impossible, But Dino DNA Lasts Longer Than Thought

In "Jurassic Park," scientists extract 80-million-year-old dino DNA from the bellies of mosquitoes trapped in amber. Researchers may never be able to extract genetic material that old and bring a T. rex back to life, but a new study suggests DNA can survive in fossils longer than previously believed.

The oldest DNA samples ever recovered are from insects and plants in ice cores in Greenland up to 800,000 years old. But researchers had not been able to determine the oldest possible DNA they could get from the fossil record because DNA's rate of decay had remained a mystery.

Now scientists in Australia report they've been able to estimate this rate based on a comparison of DNA from 158 fossilized leg bones from three species of the moa, an extinct group of flightless birds that once lived in New Zealand. The bones date between 600 and 8,000 years old and importantly all come from the same region.

Temperatures, oxygenation and other environmental factors make it difficult to detect a basic rate of degradation, researcher Mike Bunce, from Murdoch University's Ancient DNA lab in Perth, explained in a statement.

"The moa bones however have allowed us to study the comparative DNA degradation because they come from different ages from a region where they have all experienced the same environmental conditions," Bunce said.

Based on this study, Bunce and his team put DNA's half-life at 521 years, meaning half of the DNA bonds would be broken down 521 years after death, and half of the remaining bonds would be decayed another 521 years after that, and so on. This rate is 400 times slower than simulation experiments predicted, the researchers said, and it would mean that under ideal conditions, all the DNA bonds would be completely destroyed in bone after about 6.8 million years.

"If the decay rate is accurate then we predict that DNA fragments of sufficient length will preserve in frozen fossil bone of around one million years in age," Bunce said.

But he cautioned that more research is needed to examine the other variables in the breakdown of DNA.

"Other factors that impact on DNA preservation include storage time following excavation, soil chemistry and even the time of year when the animal died," Bunce said in a statement. "We hope to refine predictions of DNA survival by more accurately mapping how DNA fragments decay across the globe."

The study was published Oct. 10 in the journal Proceedings of the Royal Society B.

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'Jurassic Park' May Be Impossible, But Dino DNA Lasts Longer Than Thought

Posted in DNA

DNA decay rate makes 'Jurassic Park' impossible

Researchers in New Zealand found that DNA decays far quicker than previously considered, making it impossible to salvage usable genetic material from dinosaurs.

Don't worry, we won't have to worry about this scenario in the future.

Countless childhood dreams dissolved today upon the news that the calculated half-life of DNA figures out to around 521 years, all but invalidating the chances of a real-life "Jurassic Park."

The DNA fact-finding project involved a team of palaeogeneticists testing 158 leg bones belonging to three species of extinct giant moa birds ranging from 600 to 8,000 years old.

After running a series of comparisons between the age of the various bones and DNA degradation within each specimen, the researchers estimated that DNA's half-life works out to about 521 years after being kept in a swamp with an average temperature of 13.1 Celsius (55 Fahrenheit). Even a more ideal preservation temperature of minus 5 Celsius (23 Fahrenheit) would only result in readable DNA from specimens up to 1.5 million years old, meaning there is no possible way we can see a 65-million-year-old T-Rex waving its tiny arms about in this time frame.

DNA breaks down for a variety of reasons, including degradation from external influences such as temperature, water, soil chemistry, and so on. After half a millennium, the researchers assume that DNA continues to degrade as the nucleotide bonds within break in half. Each 521-year segment serves as another chapter of nucleotide structure breakdown and carries on until the bonds no longer exist. However, science has yet to determine the breakdown speed of DNA in environments that are more supportive of preservation, such as permafrost.

Morten Allentoft at the University of Copenhagen and Michael Bunce at Murdoch University in Perth, Australia, worked with a large team on the findings, which were published today in the Proceedings of the Royal Society B science journal.

(Via Nature)

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DNA decay rate makes 'Jurassic Park' impossible

Posted in DNA

Murder accused's DNA 'on victim'

10 October 2012 Last updated at 12:37 ET

DNA representing a one-in-a-billion match to that of a retired teacher and the man accused of her murder was found on her hand, a court has heard.

A "full DNA profile" of Stephen Farrow, 48, was found on a swab taken from the back of Betty Yates's left hand following the discovery of her body.

Farrow denies the murders of Mrs Yates, in Worcestershire, and the Rev John Suddards, in South Gloucestershire.

He claims he saw 77-year-old Mrs Yates two days before she was killed.

She was found stabbed to death in her cottage, in Bewdley, on 4 January, having been killed two days earlier.

Farrow, of no fixed address, claims he saw Mrs Yates on 30 December, but Bristol Crown Court heard the location the DNA sample was found would make it "extremely rare" to get such a strong profile days later.

Forensic scientist Christopher McKenzie told the jury: "The DNA profile obtained showed a mixture of DNA from two people which matched the corresponding DNA profiles of Mrs Yates and Stephen Farrow.

"We found that it is a billion times more likely to have come from Betty Yates and Stephen Farrow than from Betty Yates and someone other than Stephen Farrow."

Mr McKenzie said given the strength of the DNA profile he would expect there to have been either direct physical contact between Mrs Yates and Farrow or for it to have come from a bodily fluid - potentially saliva or sweat.

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Murder accused's DNA 'on victim'

Posted in DNA

Singing Mice May Join Humans and Songbirds As Vocal Learners

My high school biology teacher once told me that nothing was binary in biology except for alive and dead, and pregnant and not pregnant. Any other variation, he said, existed along a continuum. Whether or not the claim is technically accurate, it serves to illustrate an important feature of biological life. That is, very little in the biological world falls neatly into categories. A new finding, published today in PLoS ONE by Gustavo Arriaga, Eric P. Zhou, and Erich D. Jarvis from Duke University adds to the list of phenomena that scientists once thought were categorical but may, in fact, not be.

The consensus among researchers was that, in general, animals divide neatly into two categories: singers and non-singers. The singers include songbirds, parrots, hummingbirds, humans, dolphins, whales, bats, elephants, sea lions and seals. What these species all have in common and what distinguishes them from the non-singers of the animal world is that they are vocal learners. That is, these species can change the composition of their sounds that emanate from the larynx (for mammals) or syrinx (for birds), both in terms of the acoustic qualities such as pitch, and in terms of syntax (the particular ordering of the parts of the song). It is perhaps not surprising that songbirds and parrots have been extremely useful as models for understanding human speech and language acquisition. When other animals, such as monkeys or non-human apes, produce vocalizations, they are always innate, usually reflexive, and never learned.

But is the vocal learner/non-learner dichotomy truly reflective of biological reality? Maybe not. It turns out that mice make things more complicated.

Only in the last hundred years or so have researchers known that mice vocalize as part of their mating process. The reason it eluded scientists for so long is that their vocalizations cant be heard by human ears. But then, in 2005, Holy and Guo argued in a paper in PLoS Biology that the ultrasonic vocalizations produced by mice ought to be thought of as songs rather than calls.

Lots of species produce calls, and those calls serve different purposes. Some are primarily used for mating, others for indicating the presence of food, and still others to notify group members of predators. While some calls may indeed be thought of as musical, scientists tend to distinguish between calls and songs. Unlike calls, which are built of single syllables (sometimes repeated), songs include multiple syllables that are constructed in a specific (non-random) order, often with repeated phrases. Calls tend to be identical across multiple individuals of a given species, while songs tend to differ from singer to singer.

The binary distinction between singers and non-singers might not be as convincing if it were based solely on observable behavior, but it turns out that the dichtomy is reflected in neurobiology. There are special neural circuits in both humans and singing birds that are uniquely associated with vocal learning.

Mice had always been situated firmly in the vocal non-learning group, but if Holy and Guo are right in referring to mouse vocalizations as songs, Arriaga and his colleagues reasoned, then they might show the same neurobiological signature as birds and humans. One of the hallmark neurobiological features of song learners is a circuit that starts in the motor cortex on the top of the brain which projects directly to the part of the brainstem that controls the vocal organ. These circuits have never been seen in any other non-singing species, according to Arriaga, despite over fifty years of effort searching for them, particularly in vocal non-learning birds and non-human primates.

The researchers discovered that mice do have a brain circuit that starts in the primary motor cortex, projects directly to the part of the brainstem responsible for controlling the larynx, and importantly, is active when male mice sing. The difference, when compared with birds and humans, is that the circuit is weaker, more sparse. Its there, its just not as strong.

When this pathway is disrupted in singing birds or humans, they become unable to produce vocalizations that had been learned (songs), but are still able to produce their innate vocalizations (calls). So Arriaga wanted to see what would happen if he chemically disabled those circuits in some mice. While the impaired mice were still able to sing their songs, they didnt sound quite right. Both the pitch and the frequency of their vocalizations had been affected.

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Singing Mice May Join Humans and Songbirds As Vocal Learners

Knox Students Explore Belize's Marine Biology, Culture

Ten Knox College students recently snorkeled in the ocean off Belize to examine aquatic life, and they traveled throughout the Caribbean country, interacting with its residents and visiting ancient Mayan sites.

The two-week trip was an extension of a spring term 2012 course about Belize's marine biology. Knox faculty member Linda Dybas taught "Marine Biology: Field Research on the Belizean Barrier Reef" on the Knox campus, and she co-led the Belize trip with Miava Reem, technical assistant in the Department of Biology.

"This course is interdisciplinary," said Dybas, who is Watson Bartlett Professor and chair of the Department of Biology. "I teach mostly about marine biology in Belize, and also a little bit about the politics, the history, the cultural mixes, and economic development in Belize."

Students said that traveling to Belize helped them to expand on their classroom knowledge.

"What I gained from the trip was insight into what work goes into being a marine biologist and (insight into) the other kinds of ecosystems that exist around the world," said Arnold Salgado, a Knox senior from Chicago, Illinois.

"It was really cool seeing the dinner-plate sized jellyfish and the red fire sponges on the swamps, as well as the fire coral around (Tobacco) Caye," added Salgado, a biology major who is minoring in chemistry. "I was particularly interested in studying the organisms and their interactions with each other on a day-to-day basis."

"The coolest thing on Tobacco Caye was snorkeling and being able to see the coral reef and the animals in person," said Zoe Kudla, a senior history major from Ypsilanti, Michigan, with a minor in biology. "I knew it was going to be a great experience, and it exceeded my expectations." (Photo at top of page: Knox students on Tobacco Caye in Belize. Photo at left: Knox students snorkeling just off Tobacco Caye.)

Dybas has taken Knox students to Belize every other year since 2006. She said that Belize is an outstanding place to study marine biology because of its natural features, including mangrove forests, underwater caves, atolls, and the Belize Barrier Reef -- the largest in the Northern Hemisphere.

In addition, she said, "It has almost every eco-system: a high mountain ridge, lower mountains, plains, and the wonderful coastline. Because English is the primary language, Knox students can interact easily with residents of Belize and "have really interesting conversations with people their own age."

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Knox Students Explore Belize's Marine Biology, Culture

Cell signalling work scoops Nobel

Stockholm, Oct. 10 (AP): Two American researchers won the Nobel Prize in chemistry today for studies of protein receptors that let body cells sense and respond to outside signals like danger or the flavour of food. Such studies are key for developing better drugs.

The Royal Swedish Academy of Sciences said Robert Lefkowitz and Brian Kobilka had made ground-breaking discoveries, mainly in the 1980s, on an important family of receptors, known as G-protein-coupled receptors.

About half of all medications act on these receptors, including beta blockers and antihistamines, so learning about them will help scientists to come up with better drugs.

The human body has about 1,000 kinds of such receptors, structures on the surface of cells, which let the body respond to a wide variety of chemical signals, like adrenaline. Some receptors are in the nose, tongue and eyes, and let us sense smells, tastes and light.

"They work as a gateway to the cell," Lefkowitz told a news conference in Stockholm by phone. "As a result they are crucial ... to regulate almost every known physiological process with humans."

Lefkowitz, 69, is an investigator at the Howard Hughes Medical Institute and professor at Duke University Medical Center in Durham, North Carolina. Kobilka, 57, worked for Lefkowitz at Duke before transferring to Stanford University School of Medicine in California, where he is now a professor.

Lefkowitz said he was fast asleep when the Nobel committee called, but he did not hear it because he was wearing ear plugs. So his wife picked up the phone. "She said, 'There's a call here for you from Stockholm,'" Lefkowitz told The Associated Press. "I knew they ain't calling to find out what the weather is like in Durham today."

He said he didn't have an "inkling" that he was being considered for the Nobel Prize.

"Initially, I expected I'd have this huge burst of excitement. But I didn't. I was comfortably numb," Lefkowitz said.

Kobilka said he found out around 2:30am, after the Nobel committee called his home twice. He said he did not get to the phone the first time, but that when he picked up the second time, he spoke to five members of the committee.

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Cell signalling work scoops Nobel

Neural-Behavioral Sciences building set to open in 2016

A new home for life sciences at Penn is on track to open by 2016.

The School of Arts and Sciences is moving forward with its plan to construct a new Neural-Behavioral Sciences building, a 76,500-square-foot facility near 38th Street and University Avenue.

The University has already completed the schematic design the initial phase that identifies the size, overall program and cost estimate of the construction process, according to Principal Planner in the Office of the University Architect Mark Kocent. The $68.6 million project is currently near the end of the design development phase, which will likely be finalized within the next year, he added.

The Wistar Laboratories currently reside in one of the buildings that the NBS building will eventually displace. Due to Wistars temporary lease, the earliest that Facilities and Real Estate Services could demolish the site and begin building would be in 2014, according to FRES Executive Director of Design and Construction Mike Dausch.

Once it begins, however, construction will last about two years, giving the NBS building an initial expected occupancy date of spring 2016.

The new building will house the Psychology and Biology departments, as well as the Biological Basis of Behavior program and the Roy and Diana Vagelos Life Sciences and Management program, said Associate Dean for the Natural Sciences Richard Schultz.

We are thrilled to be moving forward with the construction of this building, which will be so important to the future of education and research in the life sciences, SAS Dean Rebecca Bushnell added in an email. It promises to be a vital hub for students and faculty who are committed to exploring new areas in the life sciences and neuroscience.

Though the Universitys design plans are not yet finalized, the NBS building is slated to feature offices, classrooms and small rooms for research labs and clinical testing, among other things. Additionally, the basement level of the site will include a 182-seat auditorium, which other departments within the University will be able to use for large lectures, Dausch said.

The academic departments within the NBS building will generally be split by floor to remain close to their respective labs, but according to Schultz the building will fulfill a dual purpose of consolidating the undergraduate experience and the faculty in the life sciences.

[Today], biology majors have no home where they can hang out, he said. Psychology is scattered all over the place, and BBB also really has no place The main objective is to have a place where Penn undergraduates who are life science majors have a place where they can relate to.

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Neural-Behavioral Sciences building set to open in 2016

$2.7M LSUHSC grant to reduce alcohol use & improve HIV outcomes

Public release date: 8-Oct-2012 [ | E-mail | Share ]

Contact: Leslie Capo lcapo@lsuhsc.edu 504-568-4806 Louisiana State University Health Sciences Center

New Orleans, LA Dr. Patricia Molina, Professor and Chair of Physiology at LSU Health Sciences Center New Orleans, has been awarded a $2.7 million grant by the National Institutes of Health to develop a behavioral approach to reduce alcohol use and disorders in people living with HIV/AIDS. Alcohol use disorders are frequent in this population and are strongly associated with both decreased compliance in taking as well as the effectiveness of prescribed medicines. Alcohol is also linked to increased susceptibility to infection and viral replication.

A team of scientists led by Dr. Molina will work with LSUHSC physicians at the LSU HIV Outpatient Clinic as well as the LSUHSC School of Public Health. They will enroll 250 people living with HIV/AIDS in a clinical study that will compare intervention with a Holistic Health Recovery Program adapted for Alcohol Use Disorders with a control group in achieving or maintaining viral load suppression, reducing alcohol use and HIV risk behaviors, and improving anti-retroviral therapy adherence. It is hoped that this intervention and its future implementation will improve clinical outcomes by enhancing patients' awareness of the biomedical and psychosocial consequences of alcohol use in HIV/AIDS, and by enhancing the knowledge, motivation, and skills necessary to modify behaviors that promote HIV disease progression.

"This is the first study of this sort and it is important because the Louisiana HIV+ population appears to have a high level of alcohol use disorders compared nationally, and Louisiana also has a very high number of new HIV cases diagnosed per year," notes Patricia Molina, MD, PhD, the Richard Ashman Professor of Physiology and Head of the Department of Physiology at LSU Health Sciences Center New Orleans and the grant's principal investigator.

Louisiana remains disproportionally affected by the HIV epidemic, with 18,602 people living with HIV/AIDS in 2011, 54% of whom had been diagnosed with AIDS, the 5th highest estimated state AIDS case rate. Among U.S. metropolitan areas, New Orleans ranks 9th in estimated HIV case rates (37 per 100,000) and 9th in AIDS case rates (23 per 100,000.)

LSU Health Sciences Center Comprehensive Alcohol Research Center researchers have demonstrated that chronic alcohol use elevates viral set point, increases lung viral levels during bacterial infection, promotes intestinal CD4+ and CD8+ T lymphocyte population changes that favor disease transmission, negatively affect bone metabolism, nitrogen balance, and skeletal muscle wasting, ultimately leading to accelerated disease progression to end-stage disease.

Efficacy of the intervention will lead to improved adherence to and effectiveness of ART, improved quality of life, and decreased risky behaviors that promote HIV transmission.

"Successfully decreasing the prevalence of alcohol use disorders in this vulnerable population has the potential to significantly and positively impact the HIV epidemic by decreasing the deleterious biomedical consequences of HIV infection, improving adherence to and effectiveness of anti-retroviral therapy, improving quality of life, and decreasing risky behaviors that promote HIV transmission," concludes Dr. Molina. The grant was awarded to LSU Health Sciences Center New Orleans by the National Institute on Alcohol Abuse and Alcoholism of the National Institutes of Health, and it is a five-year grant.

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$2.7M LSUHSC grant to reduce alcohol use & improve HIV outcomes

Nobel Prize for Physiology or Medicine Goes to Stem Cell Researchers

The Nobel Prize for Physiology or Medicine was announced on Monday. The award this year went to Sir John B. Gurdon and Dr. Shinya Yamanaka. The two men were awarded the Nobel Prize jointly, for their individual work in cloning and stem cell research.

Monday's recognition marked the awarding of the first Nobel Prize for 2012. The rest of the Nobel Prize recipients will be announced throughout the next two weeks.

Here is some of the key information regarding Gurdon and Yamanaka's work and Monday's Nobel Prize announcement.

* Yamanaka and Gurdon did not work together or present shared research, even though they both concentrate their studies on a similar area of research.

* Gurdon is actually being honored for work he did back in 1962. According to a New York Times report, he was the first person to clone an animal, a frog, opening the door to further research into stem cells and cloning.

* Gurdon was able to produce live tadpoles from the adult cells of a frog, by removing the nucleus of a frog's egg and putting the adult cells in its place.

* This "reprogramming" by Gurdon laid the groundwork for Yamanaka's work four decades later. Yamanaka's work, which dates back only six years, to 2006, focused on the mechanisms behind Gurdon's results.

* According to the Los Angeles Times, Yamanaka was sharply criticized at first for his own work, in which he sought to discover how cells are able to reprogram themselves the way that Gurdon's work first suggested that they could.

* Ultimately, Yamanaka was able to isolate just four cells that were needed in order to be able to reprogram other cells back to an embryonic state, allowing them to be manipulated into developing into any particular kind of cell that was needed. These cells have now been dubbed "induced pluripotent stem cells," or iPS cells, according to reports by CNN and other media outlets.

* Scientists are reproducing Yamanaka's technique in their own labs to be able to replicate disease cells, like those of Alzheimer's or Parkinson's, in order to study them and even to test the effects of potential new treatments.

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Nobel Prize for Physiology or Medicine Goes to Stem Cell Researchers

Health and nutrition begins with family

Last week the University of Idaho's Women's Center sponsored Gloria Steinem to speak at the Women's Leadership Conference. Over the last 40 years, Ms. Steinem has played a pivotal role in the women's equality movement and is the co-founder of Ms. Magazine. In 1995 she was listed as one of the 25 most influential women in America. My dream of meeting this woman was far surpassed when my colleagues and I actually got the chance to chat with her about her take on the decreased health status of our children and families in the United States, specifically obesity rates.

What were her jewels of wisdom? She brashly asserted that Family and Consumer Sciences was the most important school on campus because of the significance it plays in the threads of family. What goes on in the family is the most important factor in raising healthy children; healthy children are the fabric of the future. In her studies of other cultures Ms. Steinem believes that the home is where it begins - food, love, communication, etc. This is where modeling healthy behaviors also starts. In cultures where men and women are both involved in raising the children (partnership cultures) children flourish. Equality equals harmony and health.

If we transfer this philosophy to the obesity issue, then teaching children to lead a healthy, active lifestyle begins in the home. While we can teach health and nutrition in school, it is most powerful to teach and practice good nutrition and physical activity in the home - by both parents. When I naively suggested that more women in the work force means more reliance on fast, processed, less healthy foods, Ms. Steinem quickly reminded me that women making healthy dinners for their family was only half of the equation. Men were equally responsible. When I ignorantly suggested that men "can't cook," she again reminded me that in the '50s men "couldn't type." But with the computer revolution of the '80s they quickly learned how to. Anyone can learn anything if the motivation is there.

So what is the take home message here? We gift each other with the power to choose and make choices. We as a culture need to choose to turn around the obesity epidemic by having a unified force. That unified force starts in the home with parents teaching, modeling and practicing healthy eating for their children. Filling your plate with 1/2 fruits and vegetables, a forth starches/grains and a forth protein/meat, with dairy as a chaser is a great beginning. When children ask for snacks offer fruits and vegetables. I remember when I was young and my family would sit around watching TV, my dad would bring out apples. He would meticulously peal the apple in circles with a paring knife and give each of his four children a "peel." Then he would slice it and give us each a sixth. Then he would start all over again on the next apple. I am not particularly fond of apples, but I loved this ritual and any food experience that involved my dad. The moral of the story is getting right back to the wisdom of Gloria Steinem - the family dynamic is the backbone of the health and nutritional status of our children... and the future.

Dr. SeAnne Safaii, Ph.D., RD, LD, is an assistant professor at the University of Idaho.

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Health and nutrition begins with family

Preeminent Medical Association Issues Statement Calling For More Physician Training, Oversight for Expert Nutrition Care

JACKSONVILLE, Fla.--(BUSINESS WIRE)--

Physicians representing the American Association of Clinical Endocrinologists (AACE) today issued a position statement strongly recommending enhanced medical doctor training for and renewed focus on treatment of patients clinical nutrition needs.

At a time when the prevalence of nutrition-related illnesses is escalating significantly, both with ambulatory and hospitalized patients, many medical societies are reporting an inadequate number of physician members trained in this important specialty, said M. Molly McMahon, M.D., FACE, professor of medicine with Mayo Clinic Rochesters Division of Endocrinology, Metabolism, Diabetes, Nutrition and Internal Medicine, co-chair of the AACE Nutrition Committee and lead author of the position paper. Healthy nutrition is important for health promotion, disease prevention and disease treatment. We wish to develop focused nutrition education for endocrinologists, highlight the value of physician nutrition expertise, and address barriers in clinical nutrition practices to enhance clinical outcomes.

AACE is proposing a four-pronged strategy to address the problem: coordination of CME-accredited advanced nutrition education and training for clinical endocrinologists; an accompanying certification process; collaboration across the many medical disciplines and organizations with interests in nutrition to foster a critical mass of expertise across specialties; and widespread recognition and support of new models for physician-directed nutritional practices that will focus on the value created by such teams as relates to clinic outcomes and quality of life issues.

The statement is published in the September/October 2012 edition of the associations peer-revised medical journal Endocrine Practice (https://www.aace.com/files/position-statements/nutrition.pdf).

The American Association of Clinical Endocrinologists (AACE)

The American Association of Clinical Endocrinologists (AACE) represents more than 6,500 endocrinologists in the United States and abroad. AACE is the largest association of clinical endocrinologists in the world. The majority of AACE members are certified in Endocrinology and Metabolism and concentrate on the treatment of patients with endocrine and metabolic disorders including diabetes, thyroid disorders, osteoporosis, growth hormone deficiency, cholesterol disorders, hypertension and obesity. For more information about AACE, visit the AACE website atwww.aace.com, become a fan on Facebook atwww.facebook.com/theaaceor follow AACE on Twitter atwww.twitter.com/theaace.

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Preeminent Medical Association Issues Statement Calling For More Physician Training, Oversight for Expert Nutrition Care

Sotheby's Modern and Contemporary Southeast Asian paintings sale achieves $15.5 million

HONG KONG.- On the third day of Sothebys Hong Kong Autumn Sale Series 2012, the sale of Modern and Contemporary Southeast Asian Paintings commanded a stunning total of HK$121 million / US$15.5 million, surpassing the pre-sale estimate (HK$45 million / US$5.8 million) and achieving the highest auction total for this category. The sale also set auction records for any Southeast Asian painting and for the artist when Fortune and Longevity (pictured above) by Indonesian modern master Lee Man Fong sold for HK$34.26 million / US$4.4 million.

Bidding of Fortune and Longevity opened at HK$4 million and jumped sharply to HK$10 million after the sixth bid. The masterpiece was sold for an astonishing price of HK$34.26 million / US$4.4 million after 27 furious bids to a phone bidder. (Note: The previous auction record for Southeast Asian Paintings was also held by Lee Man Fong and was achieved by Sothebys Hong Kong when Bali Life sold for HK$25.3 million / US$3.2 million in April 2010.)

MOK Kim Chuan, Sothebys Head of Southeast Asian Paintings, said: Buyers responded with enthusiastic biddings to todays carefully curated sale of Modern and Contemporary Southeast Asian works, many fresh-to-the-market, with desirable provenance, rarity and quality, and gave us a record sale of Modern and Contemporary Southeast Asian Art. There had been extraordinary interest in Lee Man Fongs attractively estimated Fortune and Longevity, a large-scale masterpiece which is unique within the artists corpus in its scale, rarity, significance, and creative and technical brilliance. Ten bidders pursued the work, driving the final price to almost tripling the pre-sale expectation and set auction records for any Southeast Asian painting and for the artist. The sale offered fine examples of the leading artists of the Nanyang School and received strong support from Singaporean buyers. Building on our success with the Bandung school in our Spring sale we were able to source more exceptional works, for example, But Mochtars bronze Hubungan Keluanga (Family Ties), which attracted keen interest and sold for many multiples of its high estimate.

The market for this category is broadening and we have seen active participation today from bidders across the region. There were significant interests from established markets such as Indonesia, The Philippines and Singapore, and also from new markets in the Greater China Region, with increased participation from Taiwanese collectors.

The sale of Fine Chinese Paintings and Important Watches will be held tomorrow at 10am and 11am respectively at the Hong Kong Convention and Exhibition Centre.

* Estimates do not include buyers premium

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Sotheby's Modern and Contemporary Southeast Asian paintings sale achieves $15.5 million

Longevity Global Inc. Now Launches A Low Electricity Consuming And Inverter Technology Embedded Tig Welder Unit

Longevity Global Inc. continues its back to back seasonal launches. This time the leading industrial welder manufacturing company has showcased an efficient Tig welder unit which is designed by using Inverter Technology. The continuous stock update of Longevity gives the opportunity to the industrialists to own some of the most modern welding tool which can exceed all other competitor's welding equipment in terms of quality and efficiency.

Hayward, CA (PRWEB) October 09, 2012

Longevity has both hobbyists and the professional welders in mind with the TIGWELD 160 SX. This compact, dual-voltage voltage, versatile unit offers the user a simple array of controls to accurately set the welder to perform under a wide variety of situations including fine aluminum welding. The TIGWELD 160 SX allows the welder to easily switch from 220v to 110v with the adapter plug that is included while being able to produce 160 amps on both AC and DC TIG and 140amps on Stick. Whether welding aluminum or any other metal, the TIGWELD 160 SX benefits from cutting edge inverter technology. This allows Longevity Global Inc. to offer a welder with more stability while at the same time the unit is more lightweight and reliable. The TIGWELD 160 SX is one of the more versatile welders on the market and it is backed by Longevitys industry leading warranty. Longevity Global Inc. has also stocked its inventory with diverse range of plasma cutter consumables which are scarce to find in any other conventional welding accessory shop.

With myraid of Industrial Welding tools, Longevity Global Inc. gives the welders and industrialists a large pool of cutting edge technology equipped machines to choose. Categorized machines of Longevity let the industrialists and professional welders to find the best suited welding machine for specific welding job. Availability of diverse range of professional machines like plasma cutters, Tig Welder, Mig Welder and allied accessories make Longevity the industry's biggest brand. Power backup device like small diesel generators and gas generators are also few other product lines of Longevity which are liked and appreciated all over the world.

Longevity Welding is providing its dedicated service since 2001. It is growing at a phenomenal pace with high customer satisfaction, innovative products and efficient industrial production. It works in different parts of world with distributors in Canada, Mexico, Brazil, Australia, United Kingdom, and multiple other countries. Longevity Welding serve globally with manufacturing facilities with its logistic companies to effectively distribute products in a punctual and effective manner. To know more visit http://www.longevity-inc.com

Simon Katz Longevity, Inc. 1.877.566.4462 Email Information

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Longevity Global Inc. Now Launches A Low Electricity Consuming And Inverter Technology Embedded Tig Welder Unit

UK DNA expert drew a blank with tests

HAPPIER TIMES: Lloyd and Corryn Rayney on a family holiday in Canada in late 2003-early 2004. Source: PerthNow

A DNA expert based in London was called in to investigate whether Lloyd Rayney or another, unidentified "person of interest" were involved in the 2007 death of Mr Rayney's estranged wife, Supreme Court registrar Corryn Rayney.

But tests by forensic scientist Rosalyn Treliving did not shed any light on who may have been responsible for Mrs Rayney's death.

Ms Treliving, who specialises in the analysis of body fluids and the interpretation of DNA profiles, was asked by Major Crime Squad officers to examine hairs, DNA extracts and a handkerchief collected from crime scenes related to the case.

In a written statement tendered to the Supreme Court in Perth, she said her DNA tests were to "assist in addressing the issue" of whether Mr Rayney or a second person - whose name has been withheld - were involved in Mrs Rayney's death on August 7, 2007.

She said she understood Mr Rayney and the second individual were both "persons of interest" in the investigation.

The prominent Perth barrister has been on trial for three months charged with wilfully murdering his wife at the family home in Como on the night of August 7, 2007.

Prosecutors have alleged that Mr Rayney killed Mrs Rayney at their home before placing her body in the back of her State-issued car and driving to Kings Park where he buried her in a clandestine bush grave.

He has pleaded not guilty.

Ms Treliving said she examined hair and DNA extracts from Mrs Rayney's car; hair samples from outside the Rayneys' Como home; a handkerchief found in Mrs Rayney's grave; DNA from a tree branch near the gravesite and DNA extracts from hairs found at the grave, on Mrs Rayney's clothing and in the body bag in which she was placed after being removed from the grave.

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UK DNA expert drew a blank with tests

Posted in DNA

Glowing DNA invention points towards high speed disease detection

ScienceDaily (Oct. 9, 2012) Many diseases, including cancers, leave genetic clues in the body just as criminals leave DNA at the scene of a crime. But tools to detect the DNA-like sickness clues known as miRNAs, tend to be slow and expensive. Now a chemist and a biologist from University of Copenhagen have invented a method that promises to shave days off the lab work done to reveal diseases, using cheap methods and easy to use analytical apparatuses.

Chemistry researcher Tom Vosch and plant molecular biologist Seong Wook Yang invented a DNA sensor, coupling genetic material to a luminous molecule which goes dark only in the presence of a specific target. Details on their invention, Silver Nano cluster DNA-probes, are published in the high profile scientific journal ACS Nano, and Tom Vosch is understandably proud of the invention.

"We invented a probe that emits light only as long as the sample is clean. That is an unusually elegant and easy way to screen for a particular genetic target," says Vosch of the Department of Chemistry's Nano Science Centre.

DNA clues help detect disease

You could say that the inventors took their cue from crime detection. In murder cases police technicians use DNA to identify the killer. Similarly Individuals with disease are likely to have a unique miRNA profile. Any disease that is attacking a patient leaves this genetic clue all over the victim. And because the profiles of miRNAs vary by type of cancer, finding it proves beyond a reasonable doubt what made the patient sick.

Gene magnets stick to opposites

The new detection method exploits a natural quality of genetic material. A single DNA strand is made up of molecules, so called bases, ordered in a unique combination. When two strands join to form their famous double helix, they do so by sticking to complementary copies of themselves. Likewise strands tailored to match particular miRNAs will stick to the real thing with uncanny precision. But detecting this union of the strands was only made possible when Vosch and Yang paired their skills.

A real kill switch

Tom Vosch is specialized in studying molecules that light up. Seong Wook Yang is specialized in miRNA. Together they figured out how to attach the light emitting molecules to DNA sensors for miRNA detection. Vosch and Yang discovered, that when these luminous DNA-strands stick with microRNA-strands, their light is snuffed out, giving a very visible indication that the target miRNA is present in the sample. In other words: When the light goes out, the killer is in the house.

Likely to lead to high speed cancer diagnostics

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Glowing DNA invention points towards high speed disease detection

Posted in DNA