Our cells are packed with various protein-stuffed sacs, each dedicated to carrying out essential tasks. One kind of organelle is peculiar, though. Mitochondria are jellybean-shaped structures whose jobs include making the fuel that our cells use to power everything they do. What makes mitochondria strange is that they carry their own DNA. It’s not a lot of DNA–just 37 genes–but mitochondria can make extra copies of it as they grow and divide. In other words, they act an awful lot like bacteria.

About a century ago, Russian biologists proposed that mitochondria actually started out as bacteria, which set up house in our single-celled ancestors. In the 1960s, University of Massachusetts biologist Lynn Margulis resurrected the idea, pointing to certain features in mitochondria, like their double membrane, found in bacteria but not in other organelles. In the 1970s, biologists began to invent the tools that allowed them to look at the DNA in mitochondria. As predicted, that DNA matched DNA from bacteria, not from animals.

Acquiring mitochondria over 2 billion years ago was a pivotal moment in our evolution. We are eukaryotes, as are trees, mushrooms, and amoebae. We all carry mitochondria (or ...