Rest pain in one's leg is one of the symptoms of peripheral artery disease (PAD), a serious blockage of circulation that can lead to the loss of limb often related to diabetes. A treatment known as VesCell PAD uses the adult patient's own stem cells to treat the limb suffering the effects of PAD. This painless stem cell therapy was chosen by a middle-aged American diabetic woman who traveled to Thailand in the summer of 2008 in the hopes of avoiding amputation.