15 Animals That Have Been Successfully Cloned by Scientists – Interesting Engineering

Cloning, to some a glimpse of the future, to others a step too far. There can be no doubt, however, that this technology will have important ramifications for your future, for illor good no one can yet tell. Cloned steaks are currently available on supermarket shelves but cloning is nothing new. Animals have been cloned since 1885 when Hans Adolf Edward Dreisch cloned a sea urchin. Cloning may well be the saving grace for many an endangered species. If you believe inconspiracy theorieshumans have either already been cloned. There can, however, be no doubt that this is inevitable in the not too distant future.

In the mean-time, we will happily be consuming cloned meat, which in the US doesnt require producers to label as such. Lets have a look at fifteen animals that have been successfully cloned. The following list is not exhaustive and merely a selection of interesting examples for your pleasure. Youre welcome.

An Asian carp was successfully cloned in 1963 and a mere decade later Tong Dizhou also cloned a European crucian carp. We often think of cloning as a modern development so excusing the 1885 example this is actually amazing.

Perhaps the most famous of all cloned animals, Dolly was created artificially in 1996. Dolly lived to the grand old age of six. She was the first cloned mammal and to this day is considered a great success. There have been many versions of Dolly since, which is a little perturbing. The author has fond memories of first hearing of this breakthrough during his formative teenage years.

This cheeky little rodent was cloned in Hawaii in 1997. Unsurprisingly, Cumulima was the first successfully cloned mouse. She lived until the ripe old age of two years and seven months. This was a great achievement for her creators. She produced two litters and was, ahem, later retired.

The Japanese were quite prolific during the 90s and their cloning program. These two cows were created in 1998 and have subsequently been duplicated several thousand times since. Noto and Kaga have paved the way for many other clones engineered to produce improved meat and milk products.

Another example of a cloned ruminant, Mira was cloned in 1998. Mira and her sisters were created in a US lab as predecessors of livestock engineering for the pharmaceutical industry.

This family of clones, if an accurate collective term for clones, were created for modification to allow for human cell and organ transplant. Millie and her copies were created in 2000 by a US based company.

Ombretta is a great example of cloning for the good. Before Ombretta, Mouflon were an endangered species until, of course, 2001 when this species was brought back from the brink of extinction. This was a great example of how surrogacy can help to produce a viable clone of endangered species. Thanks, Ombretta.

The lab monkey world received its first clone in 2000. US-based Tetra is the first in a series of cloned monkeys that scientists could use as test subjects to learn more about diseases like diabetes.

Guar what now? A Guar is an Asian ox that has been dwindling in numbers. Thankfully, they were succesfully cloned in 2001. Sadly, Noah lived for two days and died of dysentery soon after.

Copy Cat could well be the starting gun for an entirely new industry of pet clones. Created in 2001 Copy Cat, was, well, a domestic cat. Copy Cat was the worlds first cloned pet.

Given the never-ending game of cat and, ahem, rat it is only fair to include Ralph. Ralph was one, or is it legion, of three rat pups created in 2002. Ralphs genetic makeup may well be used in research labs in the future. 129 embryos were implanted into two female rats with three being viable rats. Ok, so not a legion of rats, but it sounded cool ok? Is is just me who believes that rats arent exactly in need of cloning technology?

Mules are sterile right? Not if you clone them! Well yes, they are still sterile but this is a great way of sticking your middle finger up to biological boundaries. Idaho Gem was born in 2003.

No, not Prometheus damn your devious mindunless, well actually yes if you can speak Greek, of course. An Italian team created this cloned horse in 2003. The belief was that they could mass produce Italian stallions. Sadly the experiment failed. She was birthed by her own clone source parent.

Being endangered is not a prerequisite of cloning potential. The African Wildcat was cloned for no other reason than we just can. US scientists used Ditteaux as a template for cloning other, more vulnerable animals.

Who doesnt like ferrets? Surely if any animal was worthy of replication its these furry, limbed bitty snake beasts? Ok, I might be a bit biased. Libby and Lilly were cloned in 2004. But why? As it turns out, ferrets are useful for the study of human respiratory diseases. They are still nasty bitty furry snake monsters, however. They also smell of pee.

Sources:businesspundit.com

[Featured Image Source: PublicDomainPictures via Pixabay]

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15 Animals That Have Been Successfully Cloned by Scientists - Interesting Engineering

Everything you need to know about evolution items in Pokemon Go – CNET

Seadras need a dragon scale to evolve.

One of the new features introduced recently to Pokemon Go are evolution items. These five additions help you evolve some Gen 1 and Gen 2 Pokemon when combined with a certain amount of candy. Here's everything you need to know about these items and where to find them.

Before Gen 2 was released, all you needed to evolve a pocket monster was collect enough candies. Now, for some special Pokemon, you need to collect the candies and an evolution item.

Here are the evolution items and how to identify them:

The taser-like upgrade item you need to evolve Porygon.

Right now, only eight Pokemon evolve using anything other than candy. Here's a list and what you need to evolve them:

To evolve Onix you need a metal coat.

There are two different ways to evolve a Slowpoke.

The only way to get evolution items is by spinning PokeStops. Like with the new berries, though, they don't drop as often as balls and razz berries. After more than fifty spins at various stops, I only got one sun stone. Your mileage may vary, but don't expect to collect them quickly.

There's a rumor that you're more likely to get an evolution item when you get your seven-day streak bonus, but that hasn't been confirmed.

The one sun stone I found after more than 50 spins.

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Everything you need to know about evolution items in Pokemon Go - CNET

NASA To Host Press Conference Regarding Discoveries Beyond Our Solar System – Collective Evolution

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NASA announced today that they will be hosting a news conference providing updates about discoveries beyond our solar system. The question remains: what type of disclosure are we really going to hear?

NASA will hold a news conference at 1 p.m. EST Wednesday, Feb. 22, to present new findings on planets that orbit stars other than our sun, known as exoplanets. The event will air live on NASA Television and the agencys website. NASA

Attending the press conference will be astronomers and planetary scientists from across the world.

As stated by NASA, the focus will be on planets beyond our solar system, although no further information has been given. Many people believe this will be major information that could affect our understanding of our solar system, things beyond it and also potentially life beyond our solar system.

Its often thought exoplanets are the major hope for life elsewhere in the universe. Over the years, many have been found and information has been shared with the public about the existence of these planets, however, whistleblowers have come forward stating that NASA, intelligence agencies, our governments and others already know about intelligent life in our, as well as habitable planets, right here in our solar system as well as beyond.

For example, Canadas former minister of defence Paul Hellyer came forward after his retirementand began blowing the whistle on UFOs and extraterrestrials. His testimony is backed up by hundreds of other high ranking military and political personnel all over the world. This includes official documents released by dozens of governments worldwide that have officially acknowledged the presence of UFOs.

In one of the cases during the cold war, 1961, there were about 50 UFOs in formation flying South from Russia across Europe. The supreme allied commander was very concerned and was about ready to press the panic button when they turned around and went back over the North Pole. They decided to do an investigation and they investigated for three years and they decided that with absolute certainty that four different species, at least, have been visiting this planet for thousands of years. Theres been a lot more activity in the past two decades, especially since we invented the atomic bomb. They are very concerned about that and if we will use it again, because the whole cosmos is a unity and it affects not just us but other people in the cosmos. Theyre very much afraid that we might start using atomic weapons again and this would be very bad for us, and them also. Paul Hellyer

Below is footage we shot at Contact In The Desert in 2016 at Joshua Tree National Park.

NASA stated that the public will be able to ask questions using the hashtag #AskNasa during the conference. The agency will then hold a Reddit AMA (Ask Me Anything) session straight after the briefing.

Not surprisingly, most people are highly interested in the one thing I think is the most important next step for humanity: integrating with ETs on a mass scale.

#AskNasa where are you hiding the aliens??????

Ben Roberts (@Ren_Boberts) February 20, 2017

Is it Aliens? #asknasa

Sean Donnelly (@seanytime) February 20, 2017

Im going to be so very disappointed if its not aliens #asknasa

Anthony (@AnthIllustrates) February 20, 2017

My research over the years has led me to question the validity of what we hear in these public briefings due to the fact that NASA has lied many times in the past and many whistleblowers and declassified documents have made that clear to us.

Whether they believe they are keeping the public safe and out of chaos by withholding the reality of extraterrestrial life or not, I strongly believe it is time for all of humanity to know the truth. Its not a matter of proof at this point, its a matter of looking at the evidence available and seeing the reality.

What type of disclosure will this be? Will we be given more drips of disclosure? Will it be the entire truth? Or will NASA release information that continues to keep the public in the dark on key issues regarding our solar system, life in it and what lies beyond? We shall find out on the 22nd.

Expect full coverage of this event by us on the date and after. You can join over 200,000 others and stay in the know by signing up to our daily brief here.

Your life path number can tell you A LOT about you.

With the ancient science of Numerology you can find out accurate and revealing information just from your name and birth date.

Get your free numerology reading and learn more about how you can use numerology in your life to find out more about your path and journey. Get Your free reading.

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NASA To Host Press Conference Regarding Discoveries Beyond Our Solar System - Collective Evolution

Scientists explore the evolution of a ‘social supergene’ in the red fire ant – Phys.Org

February 20, 2017 A photograph of a Solenopsis invicta fire ant queen (large), five workers (smaller), one larva (whiteish) on a subset of the DNA sequence of their social chromosome. Credit: Romain Libbrecht and Yannick Wurm / QMUL

Scientists from Queen Mary University of London (QMUL) have discovered that the chromosome responsible for the social organisation of colonies of the highly invasive fire ant is likely to have evolved via a single event rather than over time.

Red fire ants are found in two different types of colonies: some colonies have a single queen while other colonies contain dozens of queens. The team had previously discovered that colony type is determined by a chromosome that carries one of two variants of a 'supergene' region containing more than 500 genes.

In a new research paper, published in the journal Molecular Ecology, the team from QMUL's School of Biological and Chemical Sciences sequenced the DNA and compared the genomes of two types of individuals: those carrying the supergene version responsible for colonies with a single queen, and those carrying the supergene variant responsible for colonies with multiple queens.

"We found that the two versions of the chromosome differ homogeneously over the entire length of the supergene. This suggests that a single event, such as a large chromosomal rearrangement, was responsible for the origin of this remarkable system for determining social organisation," said lead author Dr Yannick Wurm from QMUL's School of Biological and Chemical Sciences.

The team also discovered a large number of unfavourable mutations in the version of the supergene responsible for colonies with multiple queens.

Dr Wurm added: "It is likely that only a few genes among the hundreds present in the supergene region are responsible for differences in social organisation. Our finding indicates that the advantages of having several queens in the colony outweigh the costs of the unfavourable mutations in the supergene region."

This finding can help scientists understand how chromosomes evolve over time.

Rodrigo Pracana, a PhD student at QMUL and first author of the study, said: "We know that the Y chromosome in mammals has also been affected by unfavourable mutations. It is exciting to see that the fire ant social chromosome has evolved in a similar way to the human Y chromosome, although it controls social organisation and not sex."

The red fire ant, which is a native species in South America, is infamous for its painful sting, and is known in many other parts of the world where its aggressiveness and high population density have made it an invasive pest. It was accidentally introduced to the southern USA in the 1930s and has since spread to many warm parts of the world including in China and Australia. Efforts at controlling the spread of this species have largely been unsuccessful, as indicated by its Latin name, Solenopsis invicta, meaning "the invincible".

Rodrigo Pracana added: "Our discoveries could help to develop novel pest control strategies. For example, a pesticide that disrupts the social organisation in this species without affecting other species would be beneficial.

"This might be achieved by targeting the genes in the supergene region. We find almost no genetic diversity in the version of the supergene specific to colonies with multiple queens so targeting genes in this region means there would be limited potential for the ants to evolve resistance."

Explore further: Team identifies new 'social' chromosome in the red fire ant

Researchers have discovered a social chromosome in the highly invasive fire ant that helps to explain why some colonies allow for more than one queen ant, and could offer new solutions for dealing with this pest.

Since Charles Darwin, biologists have pondered the mystery of "mimicry butterflies", which survive by copying the wing patterns of other butterflies that taste horrible to their predators, birds.

Invasive animals are often most abundant in habitats impacted by humans, especially man-made habitats, such as roadsides, suburban and urban developments, and areas of intensive agricultural activity. Understanding why this ...

Scientists have identified the cluster of genes responsible for reproductive traits in the Primula flower, first noted as important by Charles Darwin more than 150 years ago.

Picture an ant colony: up to a million ants, all looking identical, harmoniously going about their busy ant lives. But with so many ants around, how on Earth do they know who's friend and who's foe?

The ruff is a Eurasian shorebird that has a spectacular lekking behaviour where highly ornamented males compete for females. Now two groups report that males with alternative reproductive strategies carry a chromosomal rearrangement ...

Gene editing, which has raised ethical concerns due to its capacity to alter human DNA, is being considered in the United States as a tool for improving livestock, experts say.

Scientists from Queen Mary University of London (QMUL) have discovered that the chromosome responsible for the social organisation of colonies of the highly invasive fire ant is likely to have evolved via a single event rather ...

Forest elephant populations in one of Central Africa's largest and most important preserves have declined between 78 percent and 81 percent because of poaching, a new Duke University-led study finds.

The winter habits of Britain's basking sharks have been revealed for the first time.

What looks like a caterpillar chewing on a leaf or a beetle consuming fruit is likely a three-way battle that benefits most, if not all of the players involved, according to a Penn State entomologist.

By tagging individual bumblebees with microchips, biologists have gained insights into the daily life of a colony of bumblebees (Bombus impatiens) in unprecedented detail. The team found that while most bees are generalists ...

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Letter: ‘Holes’ exist in evolution argument – Sioux Falls Argus Leader

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Re: Senate Bill 55: Neither creation nor macro-evolution is science.

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Glenn Fiechtner, Sioux Falls Published 7:38 p.m. CT Feb. 20, 2017 | Updated 9 hours ago

Letters to the editor tile(Photo: Argus Leader)Buy Photo

Macro-evolution through random mutations with natural selection is just one of many examples of wrong or one-sided presentations of evidence for evolution given in classrooms, today. Teachers and students should have the freedom to show the holes in these evolution arguments.

Science is defined as, Knowledge covering general truths or the operation of general laws especially as obtained and tested through scientific method. Merriam-Webster. Science is defined as, Knowledge by observation or experimentation.

Neither creation nor macro-evolution is science because neither can be observed or repeated. Both are based on belief.

Natural selection and artificial selection (selective breeding) do work, but only on the existing gene pool. Natural selection and artificial selection can be observed and repeated. This is micro-evolution and is real science. E.g., various breeds of dogs/wolves/dingoes. Also, Galpagos finches.

However, random mutations do not add new genetic information. Observed random mutations have only degraded (destroyed) information in the genes (blindness, albinism). This degradation is science because it has been observed.

The hypothesis that random mutations increase genetic information (macro evolution) has never been observed nor repeated. So, macro evolution (molecules to single-cells to fish to man) through random mutations is not science. It is a belief.

What this means is that the teaching of evolution, as taught in most classrooms and science biology textbooks, uses examples of natural selection (real science) and then mixes in a small amount of random mutations (which science shows only destroys) to explain what cannot be proved or observed macro-evolution.

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Letter: 'Holes' exist in evolution argument - Sioux Falls Argus Leader

Evolution held back by lack of oxygen – Lab News

Evolution on earth was delayed by two billion years because of low level atmospheric oxygen, according to researchers from the University of Exeter.

The scientists discovered that until there was a large rise in the number of land plants and photosynthesis increased, oxygen consumption and production remained in equilibrium. This balance ensured oxygen levels remained low.

Professor Lenton, from the University of Exeter and study co-author, said: This time in Earths history was a bit of a catch-22 situation. It wasnt possible to evolve complex life forms because there was not enough oxygen in the atmosphere, and there wasnt enough oxygen because complex plants hadnt evolved It was only when land plants came about did we see a more significant rise in atmospheric oxygen.

Using a bespoke computer model, the research attempted to understand why the great oxidation event 2.4bn years ago did not generate modern levels of oxygen. In their paper in Nature Communications, they explain how organic material accumulated in the Earths sedimentary rock. After exposure to the atmosphere, this material reacted with oxygen for the first time, creating a feedback loop of oxygen exposure and consumption.

After the increase in land plants and a doubling of photosynthesis increasing levels of oxygen disturbed the equilibrium. The scientists model suggests even though oxygen levels at the time were only between 1 and 10% of present day levels, this was high enough to help complex life to evolve on land.

Professor Lenton said: The history of life on Earth is closely intertwined with the physical and chemical mechanisms of our planet. It is clear that life has had a profound role in creating the world we are used to, and the planet has similarly affected the trajectory of life. I think its important people acknowledge the miracle of their own existence and recognise what an amazing planet this is.

The first life on Earth is believed to have begun with bacterial evolution almost four billion years ago. It was not until 600 million years ago that the first multi-cellular animals such as jellyfish and sponges were found in the ocean. Humans did not appear on Earth until 200,000 years ago.

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Evolution held back by lack of oxygen - Lab News

The Great Evolution of Gordon Hayward – SLC Dunk

Utah Jazz starting forward Gordon Hayward landed in New Orleans on Thursday, marking the first time in six years that a Jazzman has traveled to participate in the All-Star game.

Gordon Hayward described the whole experience as surreal, a description that could easily used when talking about his basketball career as a whole. His journey to becoming an NBA All-Star started years ago, long before he was considered a NBA heartthrob and long before he became Utahs first offensive option.

The once-lanky tennis player from Indiana has worked hard to transform into the reliable offensive power and decisive leader that Utah has needed for so long. Hayward has more than proven that his All-Star selection is well-deserved.

On Friday, after a long day of press interviews and while most of the other 2017 All-Stars were likely enjoying everything New Orleans has to offer, Gordon spent his afternoon working with Jazz assistant coach Johnnie Bryant. This incredible work ethic is central to the evolution of Gordon Hayward. His entire work-hard-play-hard mentality is what has driven his evolution into one of the 24 best players in the entire league.

Hes always been dedicated to the game and has made gradual improvement every season in the NBA. He has slowly bulked up, gaining pounds muscle since his sophomore year at Butler. His overall strength, both physical and mental, has increased, and that has translated into increased production on the court. But after failing to make the playoffs last season, Hayward decided that it wasnt enough. Gradual wasnt going to cut it.

Hayward went right to work after the season ended. Instead of going home to Indiana, Hayward decided to stay in Salt Lake City to work closely with Jazz coaching staff on improving his game. He even passed up the chance to play with Team USA in the summer Olympics. Instead, he stayed in SLC and challenged himself to make the final push that would evolve his overall game.

The 2016-17 season has been the best of Haywards career. Despite less game time on the court, hes averaging 22.2 points per game, a career high and the first time in his career that he has averaged more than 20 points. Hes shooting 46.5 percent from the field, 38.5 percent from the three, and 87 percent from the free-throw line. Hes also averaging 5.6 rebounds and 3.5 assists per game, giving him a shot at being one of the most versatile players to represent Utah for quite sometime.

Hayward has helped the Jazz to a 35-22 record, and at just 26-years-old, he has time to make even more All-Star appearances. Hes just barely entering the prime of his career. With his obvious dedication and work ethic, Gordon Hayward will only continue to transform his game to higher levels. Hes key to a playoff run for Utah, and its clear that hes up for the challenge.

Before Gordon Hayward and the other NBA All Stars took could take the court on Sunday night, the Roots turned the Smoothie King Center into a visual time machine as they tried to answer the one question fans always come back to.

We are culture that is obsessed with one question: Who is the greatest? said Black Thought, as the Roots began their original musical-visual performance. With the help of a handful of cultural icons, including DJ Jazzy Jeff and one half of Run DMC Darryl McDaniels, the Roots guided viewers through a retrospective (and incredibly profound) journey of each era of greatnessfrom the beboppin beginnings to the powerful present.

After listening to celebs present their arguments as to who was the greatest era in the NBA, Black Thought gave his ruling: Who really is the greatest? None of you are. True greatness is not comparison; its evolution. If this is trueif true greatness is evolutionthen Gordon Hayward could very well go down in history as one of the greats.

All you have to do is compare the player he is now to the player who took (and missed) the final shot of Butlers historic NCAA tournament run. He has evolved and transformed more as a player than most NBA players do in their entire careers. His hard work has paid off. From scrawny rookie to Mr. Steal-Your-Girl, Gordon Hayward hardly resembles the player he was when his journey began.

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The Great Evolution of Gordon Hayward - SLC Dunk

Lockport robotics team unveils creation – Lockport Union-Sun & Journal

Monday was a special day for members of the Lockport High School robotics team.

For the last six weeks, the 38 students and 27 adult mentors on the robotics team have been working more than 40 hour weeks to design, program and construct a robot that will compete in the FIRST robotics competition.

On Monday, the robotics team, dubbed Warlocks 1507, unveiled its practice robot and performed a practice run.

"I'm genuinely proud of the work we've done," said junior Keirstan Farina, who was nominated for the FIRST Tech Challenge dean's list, as was student Nate Brick.

This year's challenge, called Steamworks, has teams compete in a simulated "airship race" in the tradition of steampunk a subgenre that incorporates technological and aesthetic designs of 19th-century industrial, steam-powered machinery.

The robot must collect "fuel" by gathering and firing balls into a nine-foot-tall, two-foot-wide basket and "install" gears by picking up and depositing large, lightweight gears. Once players have collected enough gears, they can begin turning their "ship's rotors."

At the end of the match, the players have the robots climb "aboard" the ship by ascending a rope.

During Tuesday's run, the Warlocks machine a two-foot-by-two-foot square box, painted blue and made mostly with aluminum succeeded in picking up and dropping off gears, and in climbing a rope fastened to a basketball net in the high school gymnasium. None of the balls it fired made the basket, but the team's programmers are working on that.

Three other, local FIRST robotics teams "The Circuit Stompers" of Newfane High School, "The Electric Mayhem" of Nichols High School and "Alumboti" of St. Joseph Collegiate Institute were invited, but none were able to attend on time; some needed additional time to work on their robots.

Robotics Team president Jim Rogowski said that the robotics team is about much more than building robots. It also does community service work and its primary focus is on teaching students engineering skills.

"It's a community based on kids learning real STEM technology," Rogowski said. "We're teaching kids how to do engineering."

After the competition's kick-off, Rogowski had the robotics team students break into different groups to brainstorm ideas. The groups then reconvene and selected the best ones; often they will combine the best ideas from various groups.

Then the team breaks up again into smaller teams, each with its own area of expertise: the computer-aided design team, the programming team, the electrical team, the build team, the website team and the public relations and award application team.

Together, over six weeks of long nights and all-day Saturday work marathons, the teams crafted the robot almost entirely from scratch. Almost every part except the motors and wheels were either constructed in the high school's shop or printed in a 3D printer.

"At first you can't fathom it's going to happen. When you get to this point, you can't believe we did this, we designed this, we put this together," Farina said.

Although, technically, they put it together twice. The Warlocks built their final robot, which they will use in the regional competition at Rochester Institute of Technology from March 16 to 18, and a practice one, which they used Monday.

Rokowski explained that once they have to submit their final robot, that's it. It's gone for about three weeks before the regional competition. Hence, the need for a robot that students can practice with until then.

"If our kids just sit around, they don't get an understanding of how to operate the robot," Rogowski said.

Should the Warlocks succeed at the regional match at RIT, they will go on to compete in the championships in St. Louis in late April.

Team members are excited for the opportunity. But it's more a labor of love and education than a quest to win.

"It's something I fell in love with. It helped me find what I want to do in life," said Farina, who plans to go into bio-engineering.

"We're the biggest family you could ever meet," she added.

Before the practice run, students and mentors heard from Mary Ward-Schiffert, chairwoman of UAW Local 686, and William Tiger, plant manager of the Lockport GM plant. Both GM and UAW sponsor the robotics team.

Tiger praised the FIRST robotics program for teaching engineering and STEM skills to the next generation.

"I feel good that the future is in your hands," Tiger said. "You're a lot further along than I was at that age."

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Lockport robotics team unveils creation - Lockport Union-Sun & Journal

Decatur robotics teams bring their work to CAT – Herald & Review

DECATUR Jack Kramer knows he wants to be an engineer when he grows up, though he hasn't settled on an area of specialty yet.

I think it's important for us to encourage people to support FIRST because it provides opportunities for engineering and to have jobs (in the future) and that's what people in this area want. They want jobs, he said.

The Dennis School student is involved in FIRST Lego League, and members of the Decatur teams who advanced to state competition visited Caterpillar Inc. to demonstrate their robots for the employees. CAT engineers advise students in Lego League, although the focus is on students doing all the work themselves.

I show you how to do it, said Joe Kunzeman, one of the engineers who has been involved with Lego League, along with his wife, Sue, for six years. Then you work with me and we do it together. Then you do it while I watch you. Then you do it alone.

Those four steps, he said, ensure that students can do the work themselves and really understand what they're doing.

Younger students build robots out of Legos and program them to do specific tasks on a game board. They can't touch their robots once they begin competition. High school students' robots are much larger and the tasks they're assigned more complicated, but they can use a controller, that is something like you'd use to play a video game, said Clare McCormack, one of the Zip Tie Fighters coached by Kunzeman. She's a student at St. Teresa High School.

They're all sponsored by CAT and we volunteer, said Alston Pike. We're more like coaches. Our role is to kind of guide them along.

Depending on the team, the engineers might meet with the team once or twice a week or more, Pike said.

They're here to demonstrate for the staff what it is they're supporting, said Glenn Shaffer, who's the faculty adviser for the Thomas Jefferson Middle School team. It's a lot of man-hours and it's financial support. It's good for the kids to get out and demonstrate what they do.

Most of the students who participate in robotics will end up becoming engineers, said Thomas Jefferson eighth-grader Dalton Hiser, and visiting CAT is a good way for them to see where they might work someday. Working closely with CAT engineers on their robots gives them an example of someone who's already working in the field, too.

Caterpillar was nice enough to invite us, Dalton said. And they don't really know much about what we really do. This is kind of (students') baby steps into what they're going to do in the real world.

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Decatur robotics teams bring their work to CAT - Herald & Review

School robotics team ready for major competitions – Thegardenisland.com

PUHI Not many students would be anywhere near their high school campus on a teachers work day, but there arent many kids as dedicated to putting in hard work like the Island School Robotics team on Friday.

(These students) are outstanding, said James Massaro, retired teacher and leader of the robotics team. This is the best group of students that weve ever had. They designed it, they built it.

From stripping last years robot to recycle the same gears and pieces for this years competition, Island Schools robotics team has spent a lot of time over the last couple of months outside of school to get this robot ready for the Kauaibots season.

Some students havent had a free weekend since December.

I have worked 153 hours on this robot. All four years Ive been here, Ive worked over 250 hours each year on this, said Elizabeth Makizuru, a senior at Kauai High School.

Island Schools robotics team includes students from other campuses such as Kauai High, Kapaa High, Chiefess Kamakahelei Middle, St. Catherine and five home-schooled students.

Working after school and on weekends to complete the robot, the team featuring seven seniors and a few underclassmen is almost ready for competition on Oahu and San Diego.

Were in final assembly at this point, Massaro said. Weve tested all the individual components and they all work, but we just have to make sure that everything will work together now.

Early next month, eight students and 14 members will head to the first competition site in San Diego while the entire team, 26 students, will go to Oahu later in March for the Hawaii regional competition at the University of Hawaii at Manoa.

The students are able to travel to both competitions because of a $15,000 donation from Aloha Angels.

We are impressed by the challenging nature of the project, and by the dedication of the students and adult volunteers, especially that it is student-driven this year, said Aloha Angels President Ric Cox.

Cox said Aloha Angels has been stepping-up efforts to support science, technology, engineering and math programs at the request of educators.

But before the students can focus on competing, finishing touches have to be made on the robot.

Makizuru and two of her teammates, Tyres Caberto and Nygel Melchor, have fun despite the amount of work that needs to be done in order to compete at a high level.

Melchor, a Kauai High senior, said making this robot has been challenging for more than just technological difficulties. Operator error has also been an obstacle hes had to overcome.

It was kinda hard because my fingers and Tyres fingers are too fat so we couldnt get the gears inside, he said.

Because of their self-proclaimed chubby fingers a name that the trio said is now being tossed around as the official name of the robot the team has had to rely on Makizuru, team captain, to pick up the slack and install the gears, all while mentoring the underclassmen on the team.

Its definitely gotten easier over time. My freshman year was really challenging, Makizuru said. But this year has been pretty easy in my opinion. Its just a little harder since we have to teach the younger generation, and transitioning from a student to mentor has been difficult.

The team will be performing and practicing with the robot for the public at Kukui Grove Center on Saturday, March 4, from 1 to 3 p.m.

More:

School robotics team ready for major competitions - Thegardenisland.com

What we talk about when we talk about robotics – Robohub

European Robotics Week 2016. Credits: Visual Outcasts

What We Talk About When We Talk About Love is a collection of short stories by American writer Raymond Carver. In his collection, he doesnt provide a direct definition of love but instead lets the perception of the natureof love form in the minds of the reader through narrating a series of short stories.

This idea of perception leads me to my point. In myprevious post, I highlighted the widespread reproducibility issues still haunting robotics research. These issues need to be fixed if we want to talk about Robotics as a science. Like what the new journal Science Robotics aims to do. However there are still other issues to consider: what exactly is Robotics about? What does it mean when its said, you will never be able to do that within the mechatronic paradigm? Is there a kind of robotics thermodynamics? What can be done? What cant, for fundamental reasons, be done with a given approach/class of physical systems?

Areal roboticist (even in academia) might be tempted to dismiss those question as typical intellectual speculations.

There was a recent article in New Scientist about Londons Science Museums Robots called,who is really pulling the strings? If you focus solely on the perception of disappointment, after reading thearticle, you might be led to think, as I do, that we need a paradigm change. And you may understand the objectives and concerns of some not-so-mainstream communities in AI and Robotics, for example, those gathering around the Shanghai Lectures (2016 edition here). Unfortunately, its easier said than done.

I will come back on this again. Stay tuned!

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What we talk about when we talk about robotics - Robohub

Going For Gold: Students compete in robotics challenge – Martinsville Bulletin

MARTINSVILLEFor the 14th year in a row, local Piedmont Governors School students will compete in district competitions with a special guest a robot.

Piedmont Governors School Director Brian Pace hopes that this years robot, STAGS, which stands for Science, Technology and Gifted Students, will make it all the way to the final stage of the global FIRST Robotics competition, held annually in St. Louis, Missouri.

Ill be the first to tell you, Im very competitive, Pace said. We would love to do well. We like to win competitions when we go. Were happy with what weve put together. Wed like to finish first, but its not the end of the world if we dont.

Confident about their product, Team 1262 showcased STAGS to the public on Monday evening.

Guests learned about the groups history, about the upcoming competition and saw the robot in action.

The more we do it, hopefully the better we get, Pace said about making the functional object.

Each year, FIRST Robotics comes up with a new game in which a robot must compete.

Its totally different things you have to accomplish, Pace said. Its always different. You cant take the robot you made last year and tweak it a little bit.

There are several actions STAGS must successfully complete in order to move on to various rounds of the competition.

The robot has to pick things up off of the ground, hang some things on a peg and collect things, Pace said. For the first time, itll have to climb a rope. Itll go 410.

A first of its kind for the Martinsville group, STAGS climbs a rope 4'10" in the air

Seeing the robot in action is fun, but crafting a functional piece takes time and trouble shooting.

We use what were teaching. Were using math, science and technology to build this robot, Pace said.

Theres a strict time limit FIRST Robotics teams must follow. From the moment they receive instructions on actions the robot must perform, they have six weeks to construct a working piece.

This year, the Martinsville group received word the weekend the snowstorm hit in January, which affected their timeline.

We werent able to go out and get supplies right away, Pace said.

When school resumed later that week, Team 1262 got to work.

Youve got to figure out how you want to design it, build it and test it, Pace said. We try to spend the first week getting everyone together and discussing what we want it to do and how we want it to do it.

Even though copious amounts of planning go into the project, the final piece hardly ever resembles the first draft on paper.

Its just like real life. You problem solve, you collaborate. You expect it to go right and then everything goes wrong, Pace said.

While the director said he could give his students formulas and problems to solve all day long, the hands-on approach gives them real-world experience by working as a team to solve an issue.

You tweak it and you deal with problems, Pace said.

Nicholas Turner, a student on the team, helped tweak the robots drive system. STAGS started out with two sets of omniwheels and one treadwheel. However, the original design did not work the way the team hoped.

We collaborated in the lab and brainstormed ideas, Turner said.

The group ended up with two treadwheels and a set of omniwheels.

It gave us more traction on the ground, Turner said.

Throughout the process, students take on various leadership roles.

We give students the opportunity to be the drivers, Pace said.

If something goes awry, its up to the students to figure out why.

We ask them, What if this happened? What if this broke? Pace said.

Adam Wilson spoke of one mishap, which the team corrected.

Sort of the shooter mechanism showed inconsistencies, Wilson said. We found the correct angle and made sort of a backboard.

Spectators oohed and aahed as STAGS made his way through an obstacle course.

James Morrison, who came with his family to support his granddaughter, Victoria Pritchett, raved about the students skills.

Its a nice job, a very good job, Morrison said. Its very interesting.

About the size of a miniature refrigerator, STAGS is ready to make his debut at his first competition next weekend, March 4 and 5.

About the robotics program as a whole, Pace said, Were not saying were creating engineers, but were giving them a taste for it.

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Going For Gold: Students compete in robotics challenge - Martinsville Bulletin

Ingenuity, skill earn honors for students at Heartland Regional Robotics Championship – Omaha World-Herald

The 2017 Heartland Regional Robotics Championship was held Friday and Saturday at Omaha North High School.

Winners include:

Eventwide awards

Energy Award: Brobotz and Roarbotics of Clear Lake Robotics Club in Clear Lake, Iowa

Sportsmanship Award: Alice Buffett Magnet Middle School

Open tournaments

Honor award: Nerd Herd of Omaha North

Tournament Champion (three-team alliance): Robo Raiders and Nerd Herd of Omaha North, and Aurora Robotic Huskies of Aurora, Nebraska

Tournament Finalist (three-team alliance): MW Wildwest of Millard West, and Perfectly Flawed and Enginerds of Omaha North

Design Award: MW Wildwest of Millard West

Skills Champion: Nerd Herd of Omaha North

Skills Finalist: Perfectly Flawed of Omaha North

VRC High School Division Awards

Excellence Award: Legion of Doom of Benson

Tournament Champion (three-team alliance): Legion of Doom of Benson, TechnaPwn of TechnaPwn Robotics Club in Council Bluffs, and Darth Jar Jar of Millard South

Tournament Finalist (three-team alliance): Fuzzy Wuzzy 2.0 of Douglas County West, SV Wall Hacks of Brownell-Talbot and OPS Eagle Strike of Omaha Central

Design Award: TechnaPwn of TechnaPwn Robotics Club in Council Bluffs

Skills Champions: Knight Shift of Mount Michael

Skills Finalist: Fuzzy Wuzzy 2.0 of Douglas County West

Think Award: Fuzzy Wuzzy 2.0 of Douglas County West

VRC Middle School Division Awards

Excellence Award: Robohawks of Mary Our Queen Catholic School

Tournament Champion (three-team alliance): Bastion, Ork-estra and Always Watching of Brownell-Talbot

Tournament Finalist (three-team alliance): Random Bits of Gross Catholic, OPL-Millard A of the Omaha Public Library Millard Branch, and Jaegers of Cavalry Robotics in Weston, Nebraska

Design Award: Trojans of Marrs Middle School

Skills Champion: Bastion of Brownell-Talbot

Skills Finalist: Falcon Mobil of Douglas County West

Think Award: Bastion of Brownell-Talbot

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Ingenuity, skill earn honors for students at Heartland Regional Robotics Championship - Omaha World-Herald

Virtual reality will take ‘maybe a decade’ to become mainstream – Mashable


Mashable
Virtual reality will take 'maybe a decade' to become mainstream
Mashable
Despite burying us up to our neck in hype, the virtual reality industry is off to a very slow start. Apparently, VR hardware penetration in Australia will only reach 25.5 percent of households in 2021. Currently, about 2.3 percent of local households ...
Virtual reality to take a decade as users chicken out, study showsThe Australian Financial Review
Content developers well placed as virtual reality pushes toward mainstreamARNnet
Virtual reality takes hold in Aussie marketiTWire
ZDNet
all 7 news articles »

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Virtual reality will take 'maybe a decade' to become mainstream - Mashable

Virtual reality has potential to add new dimensions to marketing – Business Day (registration)

US business consultancy Forrester Research made its thoughts clear in the title of a 2016 report Virtual Reality Isnt Ready for Marketing Yet. It forecasts a wait of at least five years before there is "critical-mass consumer-adoption of high-end VR headsets".

Thats the US. Add a few more years for SA.

However, the report does predict that, during those five years, plain 360 video will flourish on lower-end VR devices. YouTube is helping to lead this trend, with a dedicated channel for the technology.

VR should not be confused with other forms of techno reality. The "real" VR environment is immersive and changes as you move through and interact with it. "Your brain really believes you are there," says Noriskin-Ender.

Theres also augmented reality, in which computer-generated objects are overlaid on real scenes. An example was the smartphone-based Pokmon Go phenomenon in 2016. And then theres mixed reality, often described as a combination of augmented and 3D. Its worth pointing out that 3D filming was touted as the future a few years ago but, besides commercial cinema movies, has mostly proved a dud.

The Forrester report suggests the US will be home to at least 52-million head-mounted VR devices by 2020. Most of those will be low-end.

It is these devices, often made of cardboard, that are expected to also fuel VR marketing growth in SA. The most common brand, Google Cardboard, is available for under R200.

Not all brands or products are necessarily suited to VR, says Net#work BBDO creative head Brad Reilly. "It works best in sectors where the full experience of the product is beyond most peoples reach."

Sport, travel and tourism are obvious candidates, as are vehicles. Besides Mercedes, Toyota SA in 2016 used VR to put enthusiasts through an offroad experience in the Hilux bakkie.

Property is another option.

"A lot of top-end Cape Town residential property is being bought from abroad," says Reilly. "Short of coming here to see everything, what better way to show them whats available, and help narrow down the choice, than by taking them on a VR tour of possible houses."

Gamification using VR to enhance branded game-playing on computer screens and digital devices is another obvious target. And what about retail? With the right technology combinations, it is possible to browse the aisles of your favourite supermarket or fashion store, to take the guesswork out of online shopping.

"In principle," says Noriskin-Ender, "the only limits to VR are your imagination and budget."

Film-makers say VR production processes are different. Visual effects studio Sinisters Christian van der Walt says: "Film-making is more technical, very process-intensive. It requires a lot more effort."

However, Velvet Films Jannine Nolan says: "Technically, its not too complicated. At the heart is a piece of equipment carrying multiple cameras, in our case eight, to provide the all-round, 360-degree effect."

One of the challenges, says Artifacts Brent Simpson, is that you can no longer have someone filming behind the camera. The 360-degree element means no one can be nearby in case they are in the shot. Reshoots are a no-no.

"In ordinary filming, you reshoot and edit in the changes. You cant do that in VR. You need a seamless, interruption-free flow," Simpson says.

For the Mercedes project, Van der Walt says his team used a pod of cameras for a 360 view of the outside world, then to compensate for lighting and depth issues recreated the cars interiors with computer graphics. For the Kyalami version, Lewis Hamilton was also superimposed into the final product.

Local Lufthansa marketing manager Jola Slomkowski says marketers are still feeling their way with VR. "Lufthansa in Germany has used it but the concept is very new here. I decided to go this route because I think that most of our communications in SA are predictable and I want to talk to customers differently. VR is a means of gaining a competitive advantage.

"Its been a learning experience for us. We are dipping our toes in without knowing quite where it will take us. The only thing we are sure of is that VR will become part of the broad marketing and communications experience."

Or, as Nolan puts it: "Virtual reality is a novelty, but one we cant ignore."

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Virtual reality has potential to add new dimensions to marketing - Business Day (registration)

There’s a completely legal reason this American dentist has an office full of human heads – Quartz

Jordan Sparks found cryonics while sifting through the Portland State University library as a student in the early 1990s. He was fascinated. He stayed fascinated through dental school, and as a practicing dentist, and while building a dental management software whose success has given him the freedom these days to pursue the dream of a deep-frozen future full time.

There are three places in the US known to store preserved human brains in the hopes of reanimation: Alcor, the sleek Scottsdale, Arizona-based facility currently housing the head of baseball great Ted Williams; the Cryonics Institute, a 41-year-old organization outside Detroit; and Oregon Cryonics, which occupies Sparkss former dentistry office in the capital city of Salem.

Running a do-it-yourself cryonics shop from a former dental practice is not easy or cheap. Sparks has invested in a fleet of scientific equipment, much acquired second-hand, including liquid nitrogen, a fume hood, a CT scanner, microscopes, a vibratome, and a microtome. And then there is this line item: a steady supply of human heads.

About once a week, Sparks receives delivery of a gray plastic bucket containing the head of a person who died a few days earlier in the states of Oregon or Washington. Sparks is the first to admit that his facility isnt ready to offer cryopreservation to the paying public. (He has taken several cases pro bono; more on those later.) To ready himself for that future, he and his team of two assistants practice brain removal, temperature monitoring, and freezing techniques on the heads of recently-expired individuals who almost certainly had no idea a start-up cryonics venture would be their final destination.

He procures his specimens from one of a growing number of for-profit body donation companies, which supply human cadavers and their isolated parts for research and education purposes. In exchange for free cremation of unused remains and the hope of turning a personal loss into a benefit for the greater good, donors sign over to businesses a body that can be sold on for thousands of dollars.

The body donation industry occupies an unusual economic loophole in the US. Its illegal to sell human tissue. But companies that provide free bodies or parts for research are allowed to charge recipients for the expenses incurred obtaining the bodieslike the cost of transport, cremation, and staff time. Businesses set those fees themselves, and theyre not published or regulated anywhere. In practice, the rise of for-profit body donation firms like the one that supplies Oregon Cryonics has created a commercial market for cadavers as robust as that of any other commodity.

Body donations have saved and enhanced countless lives. Cadaver dissection is a cornerstone of medical training. Donated bodies allow experienced surgeons to perfect new techniques without risk to living patients and facilitate research in everything from dementia to automobile safety. But no federal regulation governs the trade, state regulations are patchy, and there are no standards for what counts as legitimate research.

And when it comes to acquiring bodies from these for-profit firms, deep-pocketed private commercial enterprises are often better positioned to get them than the educational or publicly-funded institutions most donors envision when they agree to give to science.

* * *

To be clear right up front: The people whose heads ended up in Sparkss lab did not get there by becoming organ donors. When a person agrees to donate organs by joining a state registry or signing a hospital consent form, he or she enters a tightly-controlled supply chain in which specific organsthe kidneys, lungs, heart, liver, pancreas, and intestinesare recovered from brain-dead donors and transplanted within hours into carefully-matched recipients. Individuals can also consent to donate tissues like bones, skin, and tendons, which can be collected up to 24 hours after death and stored long term.

In the US, the Food and Drug Administration regulates transplantable human cells and tissues. In transplant tissue donation, material recovered from a dead person is surgically implanted into a living person. This can mean new tendons for orthopedic injuries or new heart valves for cardiac disease patients. Donated skin could be used to create skin grafts for burn victims, or in an elective breast or penile enlargement.

Non-transplant tissue donations, which covers whole-body donations, are used only for research and education. The US Food and Drug Administration (FDA) doesnt regulate them. With a handful of exceptions, states dont regulate them. A trade group, the American Association of Tissue Banks (AATB), offers standards and an accreditation program, but membership is voluntary, and only a fraction of the US companies that take whole-body donations have signed on.

Its pretty sad. Were not regulated on a federal level whatsoever. We need to be, says Alyssa Harrison, chair of AATBs non-transplant donation committee and executive director of the United Tissue Network, a not-for-profit body donation company with offices in Arizona, Oklahoma, and Florida. Harrisons business is among the handful in the industry pushing for federal regulations. While there are clear economic motivations for an established company to pursue more regulationhigher barriers to entry mean less competitionHarrison says its also in the best interest of a public that assumes such donations are regulated more heavily than they are.

Most non-transplant bodies are used for exactly the kind of productive, legitimate research that donors and their families envision. Donated bodies have led to breakthroughs in the treatment of pain management, inflammatory diseases, and dementia. Government agencies from NASA to the National Highway Traffic Safety Administration to the Department of Defense have used cadavers to test the impact of trauma on human tissue, and commercial agencies have used that research to create everything from safer cars to safer football helmets.

But donors dont get a say in where their gift goes. Its up to the collecting company to decide who gets their bodies. Aeternitas Life, the Portland-based company that provides Sparks his heads, tells donors on its website that tissues and organs are only distributed to recognized and well-respected institutions that have undergone a strict verification and approval process. The criteria for a well-respected institution or strict verification process is up to the company, which has a financial interest in making those definitions as broad as possible.

* * *

Sparks owns the building that Oregon Cryonics occupies. The only other tenant is an orthodontist whose rental space is wedged between Oregon Cryonics administrative offices and its lab. Sparks looked rueful when I asked how the orthodontist feels about the cryonics work. Its temporary, he said. He hopes to break ground on a new headquarters this summer.

A tour reveals signs of the full-service cryonics center Sparks hopes to operate one day. A coffin-sized ice bath sits in a hallway. Down the corridor is a dimly lit room with a hospital bed and a vase of fake flowers. Its reserved for patients who want to take advantage of Oregons Death With Dignity Act, which allows doctors to prescribe lethal drugs to terminally ill patients who request them. Sparks envisions future Oregon Cryonics clients choosing to end their life in the facility so that preservation can begin immediately. No human has chosen to die there yet, but one client euthanized a pet in the room. Sparks froze the animals brain and sent it to Alcor.

There are about a dozen gray buckets stacked on a tile floor. Each contains a brain. A retail refrigerator contains five gray buckets, and those each also hold a brain inside. The difference between the brains on the floor and the brains in the fridge is that the floor brains are anonymously donated specimens obtained for training purposes. The fridge brains were each specifically bequeathed to Sparks by family members of the people who once owned them.

Sparks refers to these brains alternately as patients and charity cases. They came to him days or weeks after their owners deathsan eternity in cryonics, when every passing hour means further brain degradation and diminishing chances of reanimation. They were removed by pathologists or funeral directors at the next of kins request, and brought to Sparks with the desperate hope that technology might one day bring a loved one back.

Sparks tries very hard to talk families out of such donations. He was never the kind of dentist who tried to sell people on brighter smiles, he said, and hes not the kind of cryonicist who peddles in false hopes.

From a practical standpoint, were just not really equipped to be able to deal with patients, he said. Its kind of like the first McDonalds. You have to build everything first, and then you start offering your services. Hes keeping these brains here not because he thinks theyll ever be reanimated, but as a favor to families who werent quite ready to let a loved one go.

Thats not to say the deceased felt the same way. While Alcor and the Cryonics Institute only freeze people who specifically elected to have their remains preserved this way, Sparkss patientswith one exception well discuss in a bitwere preserved at their next of kins request, not their own. On the infinitesimal chance that future technology is able to return consciousness to these brains, their reanimated owners might be extremely surprised to awake from eternal slumber in a refrigerator.

If you revive someone and they say No, I dont want thiswell, theyre welcome to commit suicide if they want, Sparks said. From a pragmatic standpoint, theyre probably going to be grateful and not want to do that.

Another difference between Alcor and Oregon Cryonics is the technology used. At Alcor, brains and bodies are frozen after a long and detailed procedure that begins moments after death. They are preserved in carefully-monitored vats of liquid nitrogen cooled to -196C. Sparks preserved these brains with chemical fixatives and popped them in the fridge.

Sparks is a pragmatic cryonicist. Current technology is nowhere close to reanimating a preserved brain, he says. Hes also in the camp of cryonicists who say theres no point in freezing whole corpses. Any future scientist that can reanimate a brain can probably build an artificial body.

Sparks is interested in protecting what he calls the memories stored in our synapses. He imagines a time when it will be possible to run a computer model of a cryopreserved brain thats able to translate the person within: the skills, personality, and memories its owner possessed in life. For now hes focused on perfecting the technique of freezing and preserving brains for that far-off future.

* * *

One recent gray afternoon in Salem, the team gathered around a stainless-steel surgical table in Oregon Cryonics lab. A mans head sat in a gray bucket on a bed of pebble-sized ice chips like the ones in hotel ice makers. The head protruded from the bucket from the nose up, eyes closed, with an expression like a relaxed bather who has just come to the surface for air.

Attended by two gloved employees wearing surgical gowns and protective goggles, Sparks picked up a cranial drill and bore a hole into the top of the head, which shook as if vigorously objecting. He then inserted three long, blue temperature probes: one on the brains surface, one 5 cm deep, and another at 8 cm. The goal is to measure the rates at which different parts of the brain cool.

We wouldnt do this on a patient because it would be causing damage to a brain, Sparks explained. This is the only way we can get the information. Then he put the donated head in a Ziploc baggie and placed it in a waiting CT scanner.

* * *

Aeternitas Life, the company supplying donated heads to Oregon Cryonics, opened for business in December 2015, two and a half years after founder and president Fineas Lupeiu graduated from Portland State University at age 18. Now 22, Lupeiu runs one of four businesses licensed in Oregon to deal in whole body donations. (Oregon Cryonics is one toothe legal designation lets them directly accept bodies of people wishing to be cryopreserved.)

The companys name is a play on eternity, in the way an individual is able to live on, Lupeiu said by phone. I think its Latin or something.

The business has accepted more than 100 donors so far. Lupeiu handles all the bodies himself, equipped with a bachelors degree in general science and a year of work each at a body donation company and a transplant tissue bank. Definitely procuring tissue the first time, its kind of a weird experience, Lupeiu said. Its an amazing thing to hold a brain or a heart or a pair of lungs. The fascination takes over the weirdness of it fairly early on.

Aeternitas distinguishes itself from its two competitors in Oregon by accepting bodies the others wontpeople with obesity, for example, or with amputated limbs. As long as the donor had no communicable diseases, were able to accept basically anyone, Lupeiu said.

Sparks was one of his first clients. Lupeiu started following Oregon Cryonics in college and got in touch after launching his business. He is proud of Aeternitass relationship with Oregon Cryonics and its role in facilitating what he sees as valuable research on the brain. He was once able to provide Sparks with a head only a few hours after its former owner died. (The donor had registered in advance, which speeds up the process; otherwise, it takes a few days.)

There are two types of body donors: people who arrange to donate their own bodies in advance of their deaths, and those whose next of kin make those arrangements after death. The first kind actively seeks out a company like Aeternitas. The second hears about such businesses from hospices, funeral directors, or other providers Lupeiu has built relationships with.

There is a powerful incentive for families to go with body donation: companies pay for all expenses associated with the bodys transportation and cremation. The average cremation in the US costs $1,100. Given that two thirds of Americans say theyd have trouble coming up with $500 in cash in an emergency, its an expense for which many families are unprepared.

As to who gets the bodies: Aeternitass client approval process includes running a background check, looking at the businesss website, seeing if the researcher has published, and doing site inspections when possible, Lupeiu said. He has watched experiments at Oregon Cryonics himself and is satisfied that its the best use to which Aeternitas Life can put the brains in its inventory.

He tells donors and their families that bodies may be used for research on the preservation and structure of the brain. He does not say that the long-term goal of that research is cryopreservation, nor that the researcher has no formal training in neuroscience. We dont specifically mention the organization, he said. We dont feel that would be appropriate, just in terms of protecting the privacy of where the donation goes and protecting our clients.

Both he and Sparks declined to divulge the exact amount Lupeiu charges per head. Sparks said he pays in the high hundreds or low thousands of dollars for each specimen. Lupeiu concurred, saying each one was a few thousand. Alyssa Harrison at the AATB says thats in line with industry norm, but its hard to find anyone in the body-donation industry who will share specifics when it comes to costs. Even the otherwise forthcoming Harrison says politely but firmly that the figures body donation firms charge for their services are not publicly available.

The Uniform Anatomical Gift Act, first passed in 1968 and revised several times since, prohibits buying or selling human tissue in the US. The law reflects an instinctive revulsion to the idea commoditizing the human body, and its also meant to level the playing field of public health: if organs were priced according to market demand, only the rich could afford organs. It is legal, however, for procurers to charge recipients of human bodies or tissues a fee to cover expenses like transportation, cremation, staff time, and disease testing.

But if those expenses arent made public, and no auditing agency is making sure theres a legitimate relationship between expenses incurred and fees charged, the prohibition on charging for bodies is a totally meaningless regulation, said Todd Olson, a retired professor of anatomy at New York Citys Albert Einstein College of Medicine. In other words, human bodies and their parts exist in a curious economic space in the US: legally they are not allowed to have monetary value, but in practice they most certainly do.

To my knowledge, the United States is the only country that has seen the development of legal entrepreneurial ventures supplying cadavers for medical education and research, wrote Michel Anteby, an associate professor at Boston Universitys Questrom School of Business in a 2009 Economic Sociology article entitled A Market For Human Cadavers in All But Name? He went on:

Arguably, our grandparents, parents, and friends are not being traded on an open market Quite the contrary, US law ensures that sufficient protection is in place so that this could never happen. However, the ability to legally acquire a cadaver and reimburse a supplier for procuring costs is an important step in creating a market infrastructure. It is a market where the goods are not priced, but the services are.

As in any goods and services market, those with more money are at an advantage. Right now its the profit driving distribution, not the benefit to humanity, Olson said. I can tell you right now that there are medical schools across the country that are really unable to teach neuroanatomy because of the difficulty in acquiring human brains.

* * *

Legally, its sufficient for companies to tell donor families that their gifts can be used for any purpose, anywhere. Ethically, bioethicists and industry leaders say, thats not enough.

If a researcher has in mind something that a family probably wouldnt have imagined, its not adequate for the family to consent to doing, quote, anything, said Robert Veatch, a professor of medical ethics at Georgetown University. Since 1988 hes been on the board of the Washington Regional Transplant Consortium, which oversees all organ donations in the Washington, DC metropolitan area.

To most scientists, tissue is tissue is tissue. Families dont see it that way, Veatch said. Certain parts of the bodyheads, hands, and uteruses in particularhave emotional significance for donors that other parts dont, Veatch said. For consent to be meaningful, donors or their families should be specifically informed if those are going to be used. And if the nature of the research is unusual, donors or their families should know that too, Veatch said. Some people might object to cryonics on religious or other grounds. In the absence of government regulation, companies should take it upon themselves to make that information available, and not just to families who think to ask.

Harrison concurs. As an example, she says, her company doesnt currently provide donor bodies to the military for ballistics testingwhich is a real use for cadaversbut if it did, that would be in its donor contract. I feel like you should be as explicit as possible, she said. We use the words disarticulation and dismemberment because I want my families to be completely comfortable that your loved one will be dismembered for the purpose of education.

Aeternitas takes a less direct approach. Their donor contract is vague (pdf). While Lupeiu says he would provide more information to any family that asked directly, he has never told anyone in explicit terms that a donors head may be used to carry out experiments in cryonics. When describing specific procedures the body undergoes after donation, he prefers to use less direct terms: for example, appendages are recovered, not removed.

We stayed away from that type of language in our terms and conditions. The way that weve worded it is a lot softer than, say, Youre separating different parts of the body and such, Lupeiu explained. The companys terms state that the body may undergo extensive preparation and long-term preservation upon donation. The most graphic line about the process is: In most cases, an open casket viewing or embalming is not compatible with donation.

People who arrange to donate their own bodies tend to be more comfortable with an anything-goes approach and with explicit details of the process, several people in the industry said. But for families who choose to donate a loved ones bodya decision often made while stressed and grieving, potentially under financial pressureit can be distressing to learn the messy reality of donation after the fact. Veatch served as an expert witness in a 1998 trial in which a Florida mans family won a judgment against a tissue bank after the mans head was discovered in a local incinerator; the court agreed that the family had been inadequately informed about the way their loved ones body would be used.

The FDA tightened regulation of the transplant tissue industry in 2005 after several high-profile cases in which patients sickened and died after receiving bacteria-infected donor tissues. The agency waved off Quartzs questions about tissues donated for educational purposes, saying that donations not for therapeutic purposes are outside the agencys scope. But the thorniest questions in non-transplant donation are of ethics, not public health. This is part of the reason its so hard to regulate the industry, Harrison said. How much information should be offered up front, when families have such different levels of familiarity with the donation process and different levels of comfort with the details? What qualifies as an unorthodox use of the human body?

In the case of Oregon Cryonics, some potential donors might be tickled to learn that their brains or those of loved ones helped advance the remote possibility of life after death. Others might object, and others still indifferent. But most in the industry agree that, at the very least, they should have the choice.

* * *

Oregon Cryonics lab technician Laura Jackson opened a gray bucket and gently removed a mans head. The team shaves specimens upon arrival, and there was stubble on his cheeks and scalp. She lifted the head and placed it on a laboratory work surface, where it faced the front of the room with an expression between repose and surprise. With a scalpel and bone saw, Jackson methodically remove the scalp and skull to reveal the brain underneath. The pieces of bone dropped into a waiting trash can with the sound of seashells clinking in a bowl.

Once the brain was isolated, the remains of the mans head would be driven across town to an unlikely storage facility: the offices of Open Dental, where Sparks brother is now CEO. Sparks led me through rows of cubicles where 110 employees take tech support calls. He unlocked a door and we entered a high-ceilinged room housing a stainless steel vat of liquid nitrogen along one wall and a chest freezer on another.

The freezer contains stacks of gray buckets holding the excess skin, bones, and tissues of the donor heads. Stickers on the buckets indicate the donors identifying numbers. When the freezer is full, Sparks will take the contents to a local crematorium. Its standard procedure at Aeternitas Life and other body donation firms to return to the donors family the ashes of remains cremated once donated parts have been removed. Whoever ends up with those parts is responsible for cremating any other unused tissue, but they dont give those ashes to the families. Sparks hasnt decided yet where to scatter the ashes. Probably at a cemetery, he said.

The vats another story. It contains the deep-frozen brain of the only Oregon Cryonics patient who specifically wanted cryopreservation, for which his estate paid Sparks $25,000. Sparks used to keep the vat at Oregon Cryonics, he explained, but the building is wood-framed, and its a fire risk. Yes, the employees in his call center know whats on the other side of the door in their office, he said. But hes the only one with the key.

The man was registered with the Cryonics Institute in Michigan, but after he died suddenly at his home, his body was not discovered for several days. The Cryonics Institute would no longer take him. By the time the mans partner arranged to ship the brain to Salem, it had decomposed to the point where Sparks believes that, even if memory retrieval becomes a real thing, itll be impossible for this patient.

On the chance hes wrong, however, Sparks is honoring the mans wishes. The brain will stay where it is, in a stainless steel cooking pot in a vat of liquid nitrogen at a software companys call center, until a better future comes calling.

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There's a completely legal reason this American dentist has an office full of human heads - Quartz

Extension: Taking care of the rocks in your life – Lifestyle – The … – Carthage Press

I have heard several variations of this narrative, however I have not been able to track down the source of this tale or its author.

I have heard several variations of this narrative, however I have not been able to track down the source of this tale or its author. I am sure that most of you have heard or read this story before. A teacher brings a large gallon glass jar in to the classroom. He sets it on a nearby table. Then, he pulls out a box of rocks and sets it next to the jar. He clears his throat, gestures to the rocks, and asks, Who would like to show us how much you can fit in the jar? Someone volunteers, he is summoned forward. He works quickly but carefully, astutely positioning rocks in the jar until it is satiated. Is the jar full? the teacher inquires. Yes! the students reply in strong unison. Can you fit any more in the jar? he asks. No! is the enthusiastic chorus. Next, the instructor produces a bag of pebbles, How about now? Somewhat hesitantly, another student raises her hand and is again beckoned forward. With greater care and less haste, she places a handful of pebbles at the top and by tapping, shaking, and rotating the jar, they make their way to fill the gaps below. Satisfied she has done her best, with hopeful confidence she returns to her chair. Is the jar full? the educator again inquires. Um, yes, is the students' cautious reply. Can you fit any more in the jar? he questions. No, they guardedly answer. Next, the instructor brings out a pail of sand. Many students begin to smile. How about now? he inquires. So another volunteer comes back to the table and using the same technique, filters the fine sand through the coarser maze of rocks and pebbles. The teacher gleefully asks, Is the jar full now? No one will venture a response. Whatever they might say, they fear it would be wrong. The professor ignores their silence, Can you fit any more in the jar? he questions. No answer. Without a word, the teacher reaches under the podium and brings forth a pitcher of water. Some students groan; others smile. Unable to contain himself, grinning he inquires, How about now? He doesn't ask for volunteers, but slowly he begins pouring the water into the jar. Gradually, it permeates every crack and crevice. He fills it to the top and then adds a bit more to overflow the jar. There is no doubt that the jar is now full. What can we learn from this? is his final query. Someone ventures to say, It means that no matter how much you've got going' on, you can always fit more in! No, the teacher exclaims, It means that unless you take care of the big things first, they will never get done!" I find myself dealing with the pebbles and sand in my life, topping it off with a large supply of water. However, I've discovered that it requires thinking and planning for me to handle the rocks. Those big and important things, are the ones that I find that without careful care I put off until tomorrow. Everyone is busy! All too often, our busyness distracts us from what is important, from what really matters, those things that could truly make a difference. Time Management doesn't usually bring relief or reduce stress, it just squeezes more into an already full day. Turn time management into how we spend our time, so that we do less. Multitasking is not really doing two things at once; it is merely quickly switching back and forth. Computers do this wellhumans dont. For us, it is actually inefficient and counter-productive. Keep a Time Log to fully understand what you do and how long you spend (or waste) on it; the results will likely shock you. Just Say No to some things even good things in order to protect yourself from over-committing and therefore being too busy to do anything well. Set Limits to how much you work, otherwise you will end up working as much as you are physically and mentally able, leaving no significant time for anything else. Know Yourself: I usually handle the pebbles and sand first and then attend to the rocks if there is time. This is not wise. I am handling trivial stuff at my peak, while reserving the important tasks for my low point. It takes an ongoing effort to do key tasks for times of peak energy, while doing lesser activities to slower times in the day. Do First Things First: Once you've taken steps to resume control over life's activities, there is then time to attend to the big things. Without the pressures of the little concerns, there is the freedom to focus on the important, removing us from the rut that all too easily goes from day to day, week to week, month to month, and even year to year without accomplishing much. Please join me today in putting first things first.

Submitted by Robert McNary, 4-H Youth Development Specialist

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Extension: Taking care of the rocks in your life - Lifestyle - The ... - Carthage Press

Long life expectancy for Leopard [IDEX17D3] – IHS Jane’s 360

Rheinmetall Defence (Stand 09-A10) is marketing its capability to upgrade the Leopard 2 main battle tank (MBT) to extend its operational life, as well as enhancing its capabilities.

The German company has already won a contract to provide upgraded Leopard 2 MBTs to Indonesia along with Marder 1A3 infantry fighting vehicles (IFVs), as well as support vehicles including armoured recovery vehicles (ARVs) and armoured vehicle-launched bridges (AVLBs).

This programme will be completed in 2017.

A contract has also been won to upgrade Leopard 2 MBTs used by Poland, and Rheinmetall is one of the two contractors awarded Assessment Phase (AP) contracts from the UK Ministry of Defence for the Challenger 2 Life Extension Programme (LEP).

The Leopard 2 upgrade is modular to enable it to be tailored to meet the end users specific operational requirements. The existing 120mm L44 Rheinmetall smoothbore gun can be retained or the 120mm L55 smoothbore gun fitted, which extends the range of the weapon by 1,500m when firing kinetic energy (KE) ammunition. The 120mm weapon can also fire the latest DM11 programmable high-explosive (HE), as well as the latest KE rounds including the DM63+ new generation. A remote-controlled weapons station (RCWS) armed with a 7.62mm or .50 machine gun can be fitted on the roof to provide a close-in self-defence capability.

The existing hydraulic gun control equipment (GCE) can be replaced by all-electric GCE and new sighting systems can be installed, including a new commanders panoramic day/ night sight to allow for hunter/killer target engagements to take place.

Cameras can be fitted to provide situational awareness through a full 360, and an auxiliary power unit can be fitted to allow all of the key subsystems to be run with the main diesel engine switched off. A high-capacity air-conditioning system can also be installed, which is considered essential when operating in high ambient temperature conditions.

Survivability can be enhanced by the installation of additional passive armour solutions or an Active Defence System (ADS), which would neutralise a variety of incoming threats to the platform, including missiles.

As well as supplying upgraded Leopard 2 MBTs, Rheinmetall can supply Buffel ARVs based on surplus Leopard 2 chassis, and the Kodiak armoured engineer vehicle (AEV).

The Kodiak AEV has been developed in association with RUAG Defence of Switzerland and has already been sold to the Netherlands, Singapore, Sweden and Switzerland.

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Long life expectancy for Leopard [IDEX17D3] - IHS Jane's 360

How Sanjay Lalbhai & Pankaj Chandra are trying to build a unique university in Ahmedabad – Economic Times

When Kevin Naik wanted to do a PhD at the interface of robotics and Internet of Things, it wasnt Ahmedabad University (AU) that first came to mind. Like many his age, he first wrote to professors at three IITs Delhi, Mumbai and Gandhinagar. The IIT faculty had clear research goals for themselves and their groups and Naiks plans didnt quite fit in. Thats when he looked to AU, where he found a willing professor along with freedom to develop his own interests in a PhD. Robotics and IoT are an unusual combination, says Naik. So only a small faculty is working in this area.

In contrast to the IIT legacy, AU is relatively new just eight years old with little reputation outside Gujarat. It makes up by providing flexibility in choice of research. AU enjoys another distinctive edge: a large endowment that provides plenty of leeway to students and faculty.

AU was set up in 2009 by the Ahmedabad Education Society, with a mandate to become a comprehensive university driven primarily by research. It was an unusual start. All private universities in India began as teaching institutions and then developed research as they grew. Almost all private universities were dominated by engineering or medicine. There was no private university at the time that mixed humanities, arts, the sciences and engineering in equal measure.

AU grew slowly initially, laying the foundation in the first five years. Institution-building picked up pace in 2014 when chairman Sanjay Lalbhai brought in Pankaj Chandra as vicechancellor. Chandra was till then director of the Indian Institute of Management Bangalore (IIMB), where he was instrumental in reconstituting the board and instituting new standards for faculty tenure, among other things. He had a few novel ideas about how a university should function and they were a departure from what universities do now. Two principles guide his vision for the fledgling university. We want to do impactful research, says Chandra. We also want to bring the visual into the classroom.

The foundation raised about Rs 670 crore from sale of land and Chandra set to work. The university had a few unusual characteristics from the beginning. One being that the vice-chancellor reports to a management board and not a family, a governance structure not common among Indias private educational institutions. Delhi-based Ashoka University is an exception to this. We have a governing board that is not easy to hijack, says Ahmedabad University chairman Sanjay Lalbhai. The university also works with a large endowment and is not so dependent on fees. Not many of Indias private universities have a large endowment, the notable exception being Azim Premji University. When the government sanctioned new IITs, each one was given only Rs 500 crore, some yet to get the full money.

Chandra has an endowment that can grow up to Rs 1,500 crore if necessary (through sale of land), and a 180-acre campus that could be designed almost from scratch. He has as much academic freedom as is possible for a private university. He also has the support of the trust and the board that share a common vision. Money, a common vision and a professional board have all brought in flexibility to the university functioning. You cannot build a world class university without top-class talent, says RA Mashelkar, former CSIR director general and member of Ahmedabad University governing board. And you cannot have top-class talent without flexibility.

All the best universities in the world have flexibility to hire the best. Mashelkars prime exhibit is Ahmed Zewail, the Egypt-born chemist who was made full professor at the age of 28. Zewail went on to do pioneering work at Caltech and win a Nobel Prize. Peter Danckwerts, one of last centurys finest chemical engineers and former professor at Cambridge University, didnt have a PhD. Indian scientific institutions and universities once had that flexibility. MM Sharma, one of Indias best-known engineers, was made professor at the University Department of Chemical Technology at the age of 27. India has lost that flexibility now.

But Chandra has flexibility and used it by getting some of the best architects in the country to design AU. Desai Architecture in Ahmedabad was campus architect. Rahul Mehrotra, founder of RMA Architects and professor of urban design and planning at Harvard University, designed the arts and sciences building. Swiss architect Mario Botta designed the library. French architect Stephen Paumier will design the student centre. Although situated in the city, the campus is being built with a central forest, being overseen by ecologists. Pankaj Chandra has a specific vision of pedagogy and culture, says Bobby Desai of Desai Architecture. The campus is built for cross faculty interaction and debate.

In the private sector, OP Jindal Global Universitys main building was designed by Paumier as a vast classical garden. AU architects, who had to work with some old buildings as well, are designing campus buildings for frequent interactions. It is being built for walking in peak summer, when temperatures are in the high 40s.

The concept of universities without departments is not new in the world. University of California at Merced was the first to try it in the 1990s. In India, IIT Gandhinagar has tried the concept with some success. Chandra has organised AU around schools and centres, not departments. Schools are formed in well-established disciplines. Centres are in subjects not well established, and are aimed at developing expertise as the subject grows in depth and relevance. The biggest future inventions are going to be multidisciplinary, says Lalbhai.

The schools are organised around four related areas. Data, materials, biology and behaviour; energy, transport, education and food; air, water, land and forest; individual and community, civilisation and constitution. The three centres are for heritage management, for learning futures and the venture studio.

The centre for heritage management is an unusual experiment, based on the premise that India has a lot of heritage but few professionals to manage it. Ahmedabad itself has many heritage sites. The university centre, however, does not study just tangible heritage like museums, art galleries and buildings. It will also study intangible heritage like language and music, not just by scholars of the discipline. The centre has a partnership with the University of Vallalodid, a 700-year-old university in Spain, through a 0.5 million grant from the European Union.

Partnerships are key to some of the programmes of Ahmedabad University. The deepest of these partnerships is with the Olin College of Engineering near Boston, a twenty-first century institution with a global reputation for innovative pedagogy. Olin College, which has no other partner in Asia, does not have classroom lectures like other universities. Students learn by doing projects.

Over the last two years, four AU faculty have spent a few months each in Olin College and imbibed its methods. The class is no longer like a podium, says Ratnik Gandhi, assistant professor at the school of engineering and applied science. It is like a studio. Undergraduate students are exposed to research methods from the beginning. In the life sciences division, among the most developed disciplines at the university, undergraduates have the luxury of a well-equipped laboratory usually accessible only to masters and PhD scholars in most places. All equipment is handled by our undergraduates, says Ajay Karakoti, nanobiologist and associate professor at the university. It is one way of immersion in the subject.

All students are required to take courses in science, data and mathematics. Engineering students have to learn biology and commerce students must learn maths. Arts subjects are also compulsory. Mayank Jobanputra, an undergraduate in information, communication and technology, had to take courses in critical thinking and argumentation, ethics, communication skills, English literature, and so on.

AU is part of the zeitgeist, part of a movement when rich philanthropists are setting up good educational institutions. The government will never be able to build a disruptive educational system, says Ramaswamy Subramaniam, professor at the Institute of Stem Cell Biology and Regenerative Medicine in Bengaluru. Hardcore scientists may not easily go to Ahmedabad, as Gujarat is not seen as an academic destination. It took four decades before IIM Ahmedabad got its current reputation. It will take equally long for a private university as well.

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How Sanjay Lalbhai & Pankaj Chandra are trying to build a unique university in Ahmedabad - Economic Times

Campaigners to keep Britain in the EU could learn from Team Brexit – WalesOnline

Campaigners for a second referendum on European Union membership could do worse than look for inspiration in the work of the men and women who fought for Brexit.

Just over a decade ago David Cameron described Ukip as fruitcakes and loonies and closet racists, mostly.

But next month Theresa May is due to trigger the process for leaving the EU. This will start a two-year countdown during which the UK Government will scramble to strike a deal with the remaining 27 member states.

People who desperately hope that Britains departure can be averted have a very narrow window of time in which to generate intense public opposition to leaving the EU. Tony Blair last week said it was his mission to persuade the country to rise up against Brexit.

The three-times election-winner declared: This is not the time for retreat, indifference or despair; but the time to rise up in defence of what we believe.

He spoke of the need to build a movement which stretches across party lines.

The hitch for the former Labour PM is that there was just such a movement in favour of remaining in the EU and it was spectacularly defeated in Junes referendum.

A majority of voters rejected the plea to stay in the EU put forward by the UKs major political parties and leading figures in business and beyond. The establishment may have regarded many eurosceptics as fruitcakes but Leave campaigners won the trust of a majority of those who went to the polls.

The best pro-EU campaigners can hope for is that they can kindle a burning desire among voters to take control and have the final say on the Brexit deal in a referendum. They have to convince swathes of the electorate that it is their democratic right to approve or reject the terms the PM and her ministers will negotiate.

Eurosceptic academics could have mailed policy papers to the House of Commons Library every day for a decade and not shifted any of the major parties to a pro-Brexit position. The genius of those who longed to cut the link with Brussels was to foment popular demand for a referendum and Ukip became enough of an electoral threat for Mr Cameron to promise such a public vote in the 2015 manifesto.

A key moment occurred back in the mid-1990s, just as Mr Blair was leading New Labour towards its first landslide. Then, Sir James Goldsmith put his cash behind the Referendum Party a proud rabble army which stood candidates in 547 constituencies.

He hardly captured the zeitgeist. The party won just 2.6% of the vote.

But the idea that the people of the UK should be asked whether the country should continue to be part of the EU had been planted.

Whats more, he demonstrated that major parties could be nudged in a eurosceptic direction.

Labour went into the 1997 election with a promise that before the UK joined the single currency, first, the Cabinet would have to agree; then Parliament; and finally the people would have to say Yes in a referendum.

The Conservatives had a similar pledge that no such decision would be implemented unless the British people gave their express approval in a referendum.

Former Conservative MP Zac Goldsmith, Sir James son, argues that keeping Britain out of the euro calamity is his fathers legacy.

Sir James passed away in July 1997 so could not lead the next chapter of the fight to take Britain out of the EU but Ukip embraced the challenge. The party may only have won one MP at the last election but it won incalculable publicity for the Brexit case.

It is remarkable that determined opponents of EU membership were able to orchestrate such a sea-change in attitudes in less than two decades.

But the challenge for pro-EU campaigners is that once Article 50 is triggered there is just two years before the UK is due to leave the EU.

With the exception of Ken Clarke, Conservative MPs have not sought to deny Theresa May the authorisation she needs to start the clock ticking.

Labours Jeremy Corbyn has said the referendum result should be respected, stating that the UK is going to be outside the European Union.

As yet, there is no prospect of a general election in the interim in which a pro-EU Referendum Party could field candidates.

What remains of the Remain team cannot replicate all of the tactics of the eurosceptics but they can preach the same core message, that a decision of such fundamental importance should not be left up to the UKs Government or even its parliament but deserves to be put to the people.

Mr Blair has not committed to supporting a second referendum but argues that if there is real change of mind, however you measure it there should be the opportunity to reconsider this decision.

There is no guarantee that another referendum would go better for Remainers than the last one. For it to be meaningful, the EU would have to agree that a No vote would not result in the UK crashing out of the union without a trade deal but would lead to a continuation of the status quo or a fresh round of negotiations.

There is also the real chance that pro-Brexit groups would successfully portray a second referendum as an attempt by an europhile elite to overturn the will of the people. The Out team might win again with an increased majority.

But if it becomes clear as the talks progress that the UK is not going to be granted a cake-eating option to have the best of every possible world then anxiety may sweep through the country. If the SNP pushes for a second independence vote and there is the genuine prospect of the UK breaking up, Whitehall may be forced to consider radical options.

Not that long ago it seemed fanciful to think that we would have a vote on EU membership. The public now has a taste for direct democracy and millions of people may well demand the decisive say on what comes next.

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Campaigners to keep Britain in the EU could learn from Team Brexit - WalesOnline