Dave Rubin interview: His new book, censorship on the left and what he sees happening in Canada – National Post

The National Posts Jonathan Kay recently interviewed American author Dave Rubin, whose tour for his new book, Dont Burn This Book: Thinking for Yourself in the Age of Unreason, was disrupted by the ongoing pandemic, and is now being done out of Rubins garage.

Jonathan Kay: Nice suit. Look what Im wearing. Thanks for making the rest of us look like crap.

Dave Rubin: I thought Id keep it professional, you know? Im on a book tour.

Kay: Whats it been like doing a book tour without actually touring?

Rubin: I got to tell you, its really bizarre, actually. The book came out on Tuesday, April 28, and I was supposed to be in New York the week before, doing all kinds of press, going on every TV show you can imagine and meeting with the publishers and all that good stuff. And then I was supposed to be on a book tour starting that night. We were gonna be at the Gramercy Theater in New York. And then I think I was going to be in D.C. and then across the country for the next month and a half or so. And instead, Im in my garage. I mean, this is my garage. I happened to have a studio in my garage. So its kind of funny. Were seeing all these CNN anchors in their kitchens, in their living rooms and things. I was a little ahead on the home studio thing. So Ive got a nice professional setup here, which is great. And, you know, theres a certain convenience to it that I can do this all from here. But I guess it is missing a little something. Talking to a live person always adds a little something else to the conversation. But Ive enjoyed this. And in many ways its allowed me to do more than I was going to be able to do because I can basically just, every day for the last four or five days, Im starting in the morning. I started literally at 6 a.m. and I go till about 8 p.m., with just minor minor breaks and maybe lunch, if Im lucky. So, you know, Im happy to talk to people. Im glad the books being well received. And you do what you gotta do.

Kay: You write that your original book idea was about how you abandoned the left side of the political spectrum and then you decided you had a more interesting idea. Tell me about that.

Rubin: Yeah. The original title of the book was Why I Left the Left, which is the title of a very popular PragerU video that I did that has about 20 million views or so. I became sort of a left the left guy. I talk about the regressive left and that the left is no longer liberal.

Thats very much in the mix, the stew of things that Ive been talking about for the last five years or so. And I started writing that book. And then I quickly realized I was like, you know, I dont know if I want to write a book about just what Im against or what I used to be. I want to write a book about what Im for. And thats what it became: Dont Burn This Book. But I lay out three moments in the book that were my seminal wake up moments.

I wont give you all three. Ill give you one of them. You may know David Webb, who is a commentator, conservative commentator on Sirius XM Patriot Channel. He guest hosts on Fox News all the time. And years ago when I was a lefty, I was on the Young Turks. We were watching a clip of Fox News and David Webb came on and suddenly they were saying all the worst things about him. He was just talking about some basic conservative beliefs. Doesnt even matter what he was talking about specifically. But suddenly they were calling him an Uncle Tom and a sellout and a race traitor. Just all of the worst things that you could say about somebody. And what they didnt know was that a few years before I had had a show on Sirius XM and although I was a lefty and David Webb was on the right, wed met in the hall one day and we started chatting. I used to go on his show every week and wed debate topics and then wed go downstairs and have a steak and have some whisky. And we were good, even though we disagreed on almost everything. But I knew him to be a good man and forthright and a passionate advocate for his positions.

It wasnt some fake thing. And yet here the Young Turks were, the supposed tolerant people, the people who loved diversity. And they were suddenly seeing a black man. And just because he didnt think the way they want black people to think he was the bad guy. He was all the worst things you could say about somebody. And because I knew him, it suddenly became so stark, so clear to me that when we think of racism, we think, oh, that youre racist. You dont want those people using a water fountain, something like that, which obviously is racist. But theres a new pernicious racism, which is that you say youre for groups gays, blacks, women.

But you cant be for whole groups because, believe it or not, black people think all sorts of different things. Gay people think all sorts of different things. Women think all sorts of different things. And to watch a group of supposedly tolerant people be angry at a black man who just thought differently than them, I realized was a new sort of systemic racism. And I say systemic because its sort of spread throughout all of the left. And even right now, Harvard discriminates against Asian people because they had too many Asian people by their measure being admitted to the university.

What the left does is they see racism almost everywhere except where it really is. They're looking for it constantly. So they have to find it.

Dave Rubin

Kay: But what about the counterargument that theres still a lot of old-fashioned racism thats still around.

Rubin: I dont see that now. Thats not to say that there isnt a KKK. There are some marginal white supremacist groups or the Westboro Baptist Church or something like that, which dont have any mainstream traction, because anytime they do any stupid little thing that, of course, the media goes crazy with it. Does David Duke exist? Of course. David Duke exists. Does he have any influence in any way whatsoever? Of course not. So I dont see actual influential bigotry out of the conservative side or on the right. But I do see it almost everywhere on the left. The left has become obsessed with identity, obsessed with gender and sexuality and the colour of skin. And I wouldnt even call that reverse racism. I would call that racism. If you rail all day long against white Christian men because theyre white Christian men, thats racism.

Again, Im not saying that there are no racist people on either side of the political aisle. Of course there are. But I think what the left does is they see racism almost everywhere except where it really is. Theyre looking for it constantly. So they have to find it. And just because you believe in low taxes doesnt mean youre a racist. Just because you believe that America should have a strong border, doesnt mean youre a racist.

These movements, they get equality, but then they the activists don't want to go out of business. So then they have to just keep finding new and new perceived oppression.

Dave Rubin

Kay: Your book is partly about what you call the pitfalls of leaving the left. What are those pitfalls?

Rubin: The biggest growing political movement or political ideology in America right now is the disaffected liberal, which is what I would say that I am I am a true liberal. And I lay out what classical liberalism is, which, of course, is about individual rights, meaning everyone that is a legal citizen of any country should be treated equally under the law. And then basically laissez-faire economics, light touch. Thats pretty much what my belief system is. Thats live and let live. And we could talk about the marginal differences between that and libertarianism.

As far as the pitfalls, well, I lay out some of the things that I guarantee will happen to you if you leave the left or not even leave the left once you start questioning it. Because if you remember four or five years ago when I started talking about my frustrations with the left, I was always saying we. I was saying we guys, we the left have abandoned liberalism. We have to fix liberalism. We have to stand for the things that were supposed to stand for, like free speech and open inquiry and not deplatforming speakers and destroying people. These are liberal principles. So I was doing this from the left. And what I think a lot of people see right now is that Im trying to give them the courage, I suppose, to be able to walk and not be destroyed once you pick one position that is counter to whatever mainstream leftist orthodoxy is of the day.

If you dont check all of those 10 boxes, they will eliminate you and they will try to mob you on social media. They will go after your employer. You will watch friends and family members turn on you and call you all of the worst things. And even if you say no, those are none of my beliefs. Well, then theyll move the goalposts and try to extrapolate something else on you. One of the very important tips that I give people is dont apologize unless you genuinely have done something wrong. Im not saying never apologize. Weve all wronged people. Weve all done things that are wrong. So you can apologize if its earnest. But I think a lot of times that we see this when the mob comes after celebrities all the time, you know, a celebrity will say something that everyone knows is basically right. You may remember Mario Lopez said that we shouldnt be something to the effect of we shouldnt be transitioning kids who are four years old, you know, gender transition. And its like everyone knows thats the truth. Thats not anti-trans. Its just that we might want to wait till theyre a little bit older. Then we could discuss all of that stuff. But he got mobbed. And then what does he do? He basically issues in a faux apology, even though we know he doesnt really apologize. He doesnt really feel any contrition about what he said.

Another one would be a Hollywood actor who Im sort of friendly with, Mark Duplass, he basically tweeted out something to the effect that Ben Shapiro is not the devil, he just has different political thoughts. He got mobbed and then deleted the tweet and issued an apology. And its like once you do that, once you apologize for something youre not sorry for, now theyve got their foot on your neck forever and you will never get up. And theyre using that power over you. So one of the things you can do is be brave and stand up for what you believe. And I think if more of us start doing it, we can actually silence that mob.

Kay: But political cults come from the right side of the spectrum, too, no?

Rubin: Lets not forget, it was mostly people on the right who were going after violent video games. Remember, they were trying to ban Mortal Kombat from the shelves. So these things are cyclical. And Im glad you brought it up because its an important point.

Kay: Were talking about censorship and preventing people from saying what they think. But its interesting that youre not talking about government censoring people which is what we would have been worried about 20 or maybe even 10 years ago. Instead, were talking about people censoring each other.

Rubin: We should always be wary of the government silencing dissent, silencing speech. But at the moment, I mean, Donald Trump can tweet whatever he wants and then what happens? The first hundred people that respond to him are usually blue check journalists or actors or activists, all telling him hes a Nazi, hes Hitler. Hes going to burn in hell. I mean, the worst things you can imagine. And guess what? Nobody knocks on their door. The Gestapo doesnt show up to drag them off to the gulag. I mean, theres no version of any of that. The bigger worry to me is that we are censoring ourselves. That is separate than the government. Its an important distinction.

Kay: Youre a gay man. Ive noticed, anecdotally, that many of the people pushing back against social-justice cultism are gay men, lesbians, Jews, Muslims people who have some trait that makes them stand out from ordinary white people. Do you think having at least some mark of outsider status gives you moral capital to push back?

Rubin: I love this question because Ive asked this of other guests of mine who are in similar situations. So Douglas Murray, the wonderful author from the U.K. whos written a lot about this and talked about immigration in Europe and all sorts of things. His last book, Madness of Crowds, is one of the best books of the year. He happens to be gay. Hes a gay conservative in the U.K. And Ive asked him about this. I see this from women. I see this from black people. It sort of gets to what I was saying earlier about why when you say youre for a group, you will actually crush all of the free thinkers within that group. And thats what Im trying to restore. Im trying to stop that from happening.

If youre a minority because of your sexuality or your skin colour or some of these things, now, I dont think that should give you power over people. I dont think that inherently makes your opinions correct. I mean, that would be absurd. As absurd as saying, you know, someone who is a white male, that his opinions are correct just because of that. So those are silly notions. But what I do think is probable is that if you are a minority of some sort, you start looking at the world from a bit of an outsider perspective. Youre not in the machine all the time. And because of that, you suddenly realize that uniqueness is deeply important. You realize there is something different.

So the most interesting example of this would be whats sort of happened to the gay community. I would say that for four decades, the gay community brought a tremendous amount of art and music and comedy and all of this cultural stuff that would start in gay clubs or whatever. I was never even into that scene at all. Much of this is before my time. But we all know that so much great music and all of this cultural stuff came from the gay community. Then, things shifted and the progressive movement sort of infiltrated the gay community. Im not saying, well, their intentions were bad. Gay marriage, by the way, is an extremely positive development that the progressives pushed because they were pushing for equality. But they were pushing for gay people to be equal, not to be above. And what happens usually is then these movements, they get equality, but then they the activists dont want to go out of business, sort of. So then they have to just keep finding new and new perceived oppression.

So what I think, unfortunately, has happened is the gay community, for whatever that term broadly means, they went from fighting for something. They went from being outsiders. And by the way, that comes with a lot of pain and all sorts of stuff. I mean, many gay people have written about this. And, you know, from my own experience, the pain and drugs and just doing stuff that I shouldnt have done, its just part of being closeted and the outsider and the rest of it. But you take that, then you get equality. And now thats great. Now things are good. But then the progressives move in and they kind of use you as a tool.

So if you notice, theres really nothing interesting coming out of the gay community these days. And that is to directly answer your question. That is why were watching so many gay people walk away (from progressive orthodoxy) right now. And by the way, its the exact same thing with the black community.

Kay: Youre an American. Do you find your political message resonates with Canadians? It used to be that a political writer like you was mostly a celebrity in your own country. But thanks to social media, things are much more global.

Rubin: It really, really does. Now, part of that I have to credit Jordan Peterson, obviously, because, you know, Jordan, whose origin he was a clinical psychologist in Toronto and professor at the University of Toronto, you know, hes sort of Canadas biggest export over the last couple of years, certainly intellectually their biggest export. And I toured with Jordan Peterson. We had many stops in Canada. Ive done some speaking events with Maxime Bernier from the Canadian Peoples party. And I do sense that there is a strong liberty movement growing in Canada. You know, as Justin Trudeau and the Liberals of Canada sort of extend their power. And I know you guys have all sorts of problems. You know, Western Canada and the Calgary area feeling that theyre sort of being left out from what the decision-making process is. I sense that there is a there is a strong liberty movement there. So we absolutely wonderful receptions in all of our Canadian stops. I love doing them. We had a running joke in every Canadian stop on the tour because I would moderate the Q-and-A at the end of the show. So the way the shows would work, I would do about 15 minutes of crowd warm-up. Jordan would give about an hour and a half speech and then we would do about 45 minutes of Q-and-A. And each time, somebody would ask if Jordan would run for prime minister and hed make you know, its a fun, silly comment about Trudeau. And it would always get a huge laugh. So I do sense that that there is a certain set of Canadians who are waking up to some of these more liberty or individual rights issues, which maybe isnt fully within the Canadian political ethos as much as it is within an American one.

But, yes, to your point. Look, were all on YouTube, were all podcasting. Were all doing all these things. And what is local is now everything. You know, its like everything is now local and whats local is now everything.

Kay: Thanks so much for joining us. Stay safe!

National Post

Follow this link:

Dave Rubin interview: His new book, censorship on the left and what he sees happening in Canada - National Post

Twitter accused of ‘censorship’ after banning Wings Over Scotland accounts – The National

WINGS Over Scotlands Stuart Campbell has accused Twitter of censorship after two of his accounts were banned.

The social media platform has taken action against the pro-independence bloggers @RevStu and @SealandGazette profiles for "evading a permanent suspension".

It comes a month after Campbell's Twitter account for a new pro-Yes party, @WingsPartyScot, was banned as soon as it was created.

The blogger hit back at Twitter over the latest action, saying that his @RevStu account predates @WingsScotland by years and was in constant use.

He commented: "The allegation that these accounts have been used to evade a permanent suspension are obviously ridiculous and false.

The @RevStu account preceded the @WingsScotland one by years and has been in constant use since its creation, and the @SealandGazette one was only used during a technical hitch with the @RevStu one which was subsequently resolved.

READ MORE:Another Wings Over Scotland Twitter account locked

The blogger added: "Twitter has still never given any explanation of how the Wings account broke any of its rules, because it did not.

These actions are quite simply direct censorship and interference in the political affairs of a country by an unaccountable, unelected foreign corporation, and even people who hate Wings Over Scotland should be extremely alarmed by."

Twitter confirmed the @RevStu and @SealandGazette accounts had been permanently suspended for violating our platform manipulation and spam policy.

The website added that the @WingPartyScot profile was suspended because it was linked to an account that had been suspended for violations of our hateful conduct policy.

Read more:

Twitter accused of 'censorship' after banning Wings Over Scotland accounts - The National

The Darlings are discouraged and disheartened by live stream censorship – The Province

Local nonbinary drag theatre collective The Darlings have had two performances taken down from Facebook.PNG

Vancouver nonbinary drag collective The Darlings has a dedicated audience for its creative and cutting-edge performances. But since the group took its show online, its work is being targeted.

Both the March 29 broadcast debut and the April 26 followup were subject to reports that they contravened Facebooks terms and guidelines and were taken down following being reported.

In a statement posted on The Darlings Facebook page, the members point out that queer artists are being silenced by such actions and that the process to get reinstated on the viewing platform is extremely onerous. The video goes on to point out that the artists were even practicing self-censorship of its content to avoid contravening Facebooks terms and guidelines. This is particularly unsettling for queer artists everywhere being comfortable with using online platforms to deliver their art in the absence of queer spaces.

For now, both performances can be viewed on Vimeo.

I like to assume that it was someone random, and not direct targeting, because in most cases that is the case, said The Darlings Continental Breakfast. There are people out there who dont want to be seeing queer programming being accessible. And if anything you do can be seen as even being PG-13, it can get reported.

The first report was lodged when member PM was showing bare feet while wearing latex. For the second show, Continental Breakfast even had nieces watch it after it aired for extra vetting. The performer admitted to feeling calm and confident going into the event.

We were on the edge of our seats for the first show, because we didnt know how it would go, they said. So we completely adjusted our content to bring forward a family-friendly show that was sensitive, gentle and touched on vulnerability. Its really hard to see someone still report that.

With nearly 10,000 views across both shows, demand clearly exists for The Darlings work. But the group says being shut down the second time cut-off its audience in the first 15 minutes and the numbers were seriously impacted. This has lead The Darlings to take a break and reconsider alternative routes which do not risk the integrity and viability of their work.

Member Rose Butch stated that being silenced on the most accessible platform available to broadcast to viewers was discouraging and disheartening.

sderdeyn@postmedia.com

twitter.com/stuartderdeyn

Originally posted here:

The Darlings are discouraged and disheartened by live stream censorship - The Province

Facebook Won’t Fudge Censorship Oversight, Qumra Sells $80 Million in Holdings and Juganu Revolution in Today’s Roundup – CTech

Facebook wont fudge content oversight, says Israeli legal expert. Emi Palmor, former director-general of Israels Ministry of Justice, was recently appointed as one of the 20 founding members of Facebook's Oversight Board. Read more

Qumra Capital sells $80 million in holdings to StepStone Group. Among the companies whose holdings were sold to StepStone are Fiverr, JFrog, AppsFlyer, Riskified, and Minute Media. Read more

Interview | Juganu wants to light the way forward in the digital revolution. With investments from telecom giants Comcast Ventures and Amdocs, Israeli startup Juganu is aiming to revolutionize light and connectivity through an innovative solution. Read more

Opinion | Mangrove Capital exec says Israeli tech does not need a bailout but could definitely use a slight nudge. Roy Saar responds to fellow investors who called on the Israeli government to refrain from bailing out startups. Read more

Opinion | Telemedicine, which gained momentum due to Covid-19, will be with us long after it recedes. Just as what counts as normal in our day-to-day lives may be changing, what counts as normal in healthcare provision will also change. Read more

View post:

Facebook Won't Fudge Censorship Oversight, Qumra Sells $80 Million in Holdings and Juganu Revolution in Today's Roundup - CTech

10 Male Sitcom Characters From The ’80s That Would Never Fly Today – Screen Rant

Sitcom characters, and sitcoms themselves from the '80s, were very different, which is why these 10 male characters would never fly nowadays.

While we're seeing a lot of TV shows from yesteryear being rebooted, many new ones are appearing as well. And they reflect the current state of the world, our changed attitudes, political correctness, and more.

The way things have changed so dramatically over the last few years means that some characters that were popular in shows from past decades really wouldn't fly today.

RELATED: 10 Male Sitcom Characters From The '90s That Would Never Fly Today

Who exactly? Here are some from the '80s.

A bartender who is both a recovering alcoholic and a notorious womanizer? Both of these things would be frowned upon these days. Some might say that Sam working in and owning a bar would be triggering to his alcoholism.

Meanwhile, his treatment of women on this iconic showwould be considered just wrong, along with the storyline that Diane only decides to pursue her dreams when he encourages her to do so on their wedding day. Really?

A young man moving in with his best friend to help him raise his three young daughters after his wife unexpectedly passes away leaving him a single father is a lovely story. However, that man still living in the basement well into his 30s when the kids are now teenagers could seem suspicious.

Some people thesedays don't want to see dad's best friend give a teenager girl advice about dating. Nosy neighbors would have confronted him about this.

Tony himself is a great character, but a male housekeeper working for a powerful female executive isn't groundbreaking today like it was when this show first debuted in the late '80s.

RELATED: 10 Sitcoms With More Female Main Characters Than Male

The show was progressive for its time but today, the character wouldn't shock anyone. And Angela as the wealthy and hard-working single mother is pretty much ubiquitous today.

This series, which aired in the '80s and '90s, was about a lower-to-middle-class family just trying to get by. The dad, Al, was a shoe salesman who was presumably depressed about his life, mourning his glory days of high school football.

Aside from his treatment of his wife and two teenage kids, Al insulted just about anyonehe could, including customers who came into his store. His favorite targets were overweight women, and no way some of the things he would say on the show would be allowed in a sitcom today.

It isn't so much Jack who wouldn't fly today as it would be the entire concept of the show. A young man named Jack who needed a place to live moved in with two young women, and the only way the conservative landlord was okay with the arrangement was because he was told Jack was gay. He was, of course, not gay at all, and in fact a pretty big womanizer.

Jack having to pretend he was gay and "act" gay throughout the series led to plenty of high jinks. But the character just wouldn't fly today.

Aside from the obvious fact that the character was designed to make fun of foreigners, the over-the-top portrayal would be considered totally offensive today.

RELATED: 10 Female Sitcom Characters From The '90s That Would Never Fly Today

And so would Balki's ridiculous outfits, naivety, and total cluelessness. It's one thing to have a language barrier, but Balki made it seem as though small-town people from other countries had zero idea about American culture.

It's a wonder how they ever thought an elderly man would be able to adopt a young girl back when this show aired, but it is even more unbelievable now.

On the late '80s series, Punky is being raised by her foster parent, an elderly window who decides to try and adopt her. Even though the show portrays the struggle for Henry to gain custody of the abandoned child who showed up in his building, chances are slim that a man of his age would ever win custody of a random young girl.

The whole idea behind this show would never fly today. Two single men are struggling with their careers and decide to disguise as women so they can afford an apartment together.

RELATED:10 Underrated LGBTQ+ Movies of the Decade

Sure, it was hilarious but viewers would look down on a show where two men pretend to be women in order to gain an advantage in life.

George was a successful businessman who first appeared in the '70s sitcom All in The Family. It's a nice rags to riches story, and it touched on a lot of cultural and racial topics that was groundbreaking at that time.

Today, the character,however, wouldn't be so groundbreaking. Plus, viewers would be angered that a successful African-American man leading a sitcom also had to be rude, bigoted, and not very intelligent, despite his career achievements.

Can someone imagine a family hiring a random young college student to live with them and, in exchange for room and board, he is tasked with caring for their children? People aren't as trusting nowadays so this would never happen.

It's a shame since the series, which aired from 1984 through to 1990, was really great and showed how a young man could mature quickly after having to care for children. But today, no sane parent would ever be okay with such an arrangement.

NEXT: 10 Sitcoms With An All-Female Core Cast

NextIt Would Be Extremely Painful: 10 Hilarious Dark Knight Bane Memes We Love

A professional writer and editor with 18+ years of experience, Christine, now a freelance writer/editor, is a self-professed TV fanatic with tastes that vary considerably from comedies to dramas, sci-fi, and more. She can usually be found binging a new show at night, coupled with a glass of red wine. With a long history writing in the field of consumer tech, she now also writes on topics from entertainment to parenting, lifestyle, marketing, and business. She resides in Toronto, Ontario in Canada with her husband and young son.

Continued here:

10 Male Sitcom Characters From The '80s That Would Never Fly Today - Screen Rant

Furry Freak Brothers coming this fall, voiced by Woody Harrelson, John Goodman, Pete Davidson, and Tiffany Haddish – Boing Boing

Yesterday saw the online premier of a mini-episode of a new animated comic series based on the classic Gilbert Shelton underground comic, the Fabulous Furry Freak Brothers. As a hippie wannabe teen in the 70s, this (and Zap! Comics) was everything to me.

In 1969, life in San Francisco consists of free love, communal living, and political protest. Freewheelin Franklin Freek (Harrelson), Fat Freddy Freekowtski (Goodman), Phineas T. Phreakers (Davidson) and their mischievous, foul-mouthed cat, Kitty (Haddish) spend their days dodging many things - the draft, the narcs, and steady employment - all while searching for an altered state of bliss.

But after partaking of a genetically-mutated strain of marijuana, the Freaks wake up 50 years later to discover a much different society. Quickly feeling like fish out of water in a high-tech world of fourth-wave feminism, extreme gentrification and intense political correctness, the Freaks learn how to navigate life in 2020 - where, surprisingly, their precious cannabis is now legal.

OK, sounds good. But is it? If the reaction to the first mini-episode is any indication, maybe the Freaks should have remained in their drug-induced coma. As one Facbooker commented: "Get yourself a collected set of the original comic and skip this drivel!"

Visit The Nib to read Gemma Corrells timely and accurate video conference call bingo comic.

The Angel, The Automobilist, and Eighteen Others is a new collection of early drawings by eccentric illustrator and storyteller Edward Gorey (1925-2000). Over at The Comics Journal, Mark Dery, author of the Gorey biography Born to Be Posthumous, reviews the slim new volume while considering where Goreys odd oeuvre sits (or doesnt) in the comic []

Award-winning comic creators Brian K. Vaughan and Marcos Martin launched Panel Syndicate in 2013 as a digital-only, name-your-price publishing outlet for their near-future Internet noir The Private Eye. Theyve released several comics through this imprint since then from themselves, and from other creators that all fit under the same DRM-free, pay-what-you-want f0rmat, with []

It seemed like such a great idea at the time. You wanted to put together a video for a loved one, including all their family and friends singing their praises, making their life look as epic as a Hollywood production. Oh, it was a Hollywood production, all right. Contributors showed up late and sent weird []

Fear is ripe soil for the unscrupulous. With so much uncertainty and concern over our health and the broader world economy, cybercriminals have been playing on that fear to steal a few extra dollars out of the most scared and vulnerable. The U.S. Secret Service warned that phishing attacks were up significantly and scams over []

Drummers hear all the jokes. What do you call a drummer with half a brain? Gifted. How is a drum solo like a sneeze? You know its coming, but theres nothing you can do about it. What do you call a drummer that breaks up with his girlfriend? Homeless. Drummers hear the jokes and []

See the article here:

Furry Freak Brothers coming this fall, voiced by Woody Harrelson, John Goodman, Pete Davidson, and Tiffany Haddish - Boing Boing

McKinsey, BCG and Bain advice on surviving COVID-19 – The Australian Financial Review

These include dealing with any problematic offshored and outsourced operations, establishing hi-visibility leadership, deploying 'pop-up' business models and, if required, making the difficult decision to reduce costs by cutting jobs.

A spokeswoman for BCG said the firm had published dozens of articles "covering many different themes and addressing priorities of different industries working in different countries at different stages of this crisis".

"There is not a one-size fits all approach to business strategy at a time of discontinuity," she said.

"Some companies are overwhelmed with demand, and others are [very] short of demand. The pandemic has some of the characteristics of a one-off shock [differs by country], but with prolonged effects in many areas and likely permanent effects in others. Different governments have provided different support models for business, such that each countrys situation is different, often with differences within a country by state or region."

"Our general point of view is therefore equally not one-size-fits all. What we have consistently said is that leaders need to pull levers that will help them be resilient, and also help them prepare for growth on the other side of the crisis," she said.

A spokeswoman for Bain said the firm's consultants had been initially focused on "helping companies get back to work safely and effectively" amid the pandemic.

"The team have deconstructed four of the most common workplaces - customer-facing [stores, banks, restaurants], manufacturing, warehouse and distribution centers, and office. They have also detailed examples of the six risk-mitigation responses that companies might need to put in place in each," she said.

"The basis for this thinking comes from our overall strategic approach to navigating the COVID-19 crisis called Act Now/Plan Now. This approach emphasises the dual set of activities business leaders must focus on simultaneously to protect the business today and recover and retool for the new world."

McKinsey has noted that the outbreak is "first and foremost a human tragedy" when outlining how businesses could respond to the crisis.

"We suggest that in order to come back stronger, companies should reimagine their business model as they return to full speed," a recent article from the firm notes.

"The moment is not to be lost: those who step up their game will be better off and far more ready to confront the challenges - and opportunities - of the next normal than those who do not.

"There are four strategic areas to focus on: recovering revenue, rebuilding operations, rethinking the organisation, and accelerating the adoption of digital solutions."

ICG founder David Moloney.Supplied

Mr Moloney said that clients were now requesting advice on how to adapt their business models to suit the new environment.

He added that ICG was also helping clients replace offshoring and outsourcing arrangements which have proven fragile during the pandemic, due to travel restrictions and lockdowns.

"There is some talk about supply chains but as the same consultants were the champions of offshoring and outsourcing as a way to cut staff costs, they haven't highlighted the about-turn in their recommendations," he said.

"Companies need to create local alternatives which will be anti-fragile."

ICG's human capital leader, Greg Barnier, said leaders had to shift from helping employees feel safe to charting a path for a return to normal working conditions.

"Good leaders are acknowledging that in these circumstances you can not separate work from home. They are accepting and acknowledging the 'interruptions' or conflicting priorities to the work day that may bring, such as children or family pets appearing in zoom meetings, home schooling demands [and so forth]," he said.

"A challenge for employers in the city may be the reluctance of people to return to work early due to concerns of safety in public transport, or a preference for more flexible work options now that many employees have experienced work from home."

Mr Moloney said that in addition to helping companies develop tactical 'pop-up' business opportunities, companies might need to look at ways to dramatically reduce their cost base.

"The firms all talk about cost reduction but they don't say how or why. The number one option is to reduce labour. You are moving customers and staff to digital channels. What the virus has created is an opportunity to step-change digital migration," he said.

"It's a gap [caused by] political correctness. No one wants to talk about cutting jobs when everyone is talking about protecting jobs. At the moment it is still to early to talk about staff reductions, but of course the virus has exposed pockets of unproductive labour and accelerated digitisation so it's created an opportunity to right-size."

See the original post here:

McKinsey, BCG and Bain advice on surviving COVID-19 - The Australian Financial Review

Vitagene Launches The First FDA Authorized Saliva based Zero Contact COVID-19 At Home Test – Business Wire

SAN FRANCISCO--(BUSINESS WIRE)--Vitagene, the precision health company, announced the immediate availability of 50,000 FDA authorized Zero Contact at home COVID-19 test kits for use during the current public emergency. Vitagene is using the 1Health.io platform to facilitate compliance with FDA requirements for assessment of symptoms, telehealth and electronic tracking of the test kit.

Simple At-Home Testing: Currently, consumers who are showing symptoms of COVID-19 infection are expected to drive or take mass transit to a clinic or stay for hours in a drive-through testing line. With the Zero Contact COVID-19 test, patients will get a kit at home eliminating the need to drive or be at risk going to a clinical setting.

Our mission as a team is to help our customers improve their health and wellness, said Mehdi Maghsoodnia, CEO at Vitagene. Our customers number one need right now is access to COVID-19 testing. That is why our team, alongside our partners, have been working day and night to bring this test to market with physician approval, telehealth supervision and a clear chain of custody tracking.

Protect Healthcare Providers: The current COVID-19 tests require that the healthcare provider be in the same room as the patient with symptoms, creating risk of infection for the healthcare provider. Once the traditional specimen collection is conducted, the provider then needs to disinfect their garments to minimize the risk of cross contamination. With Zero Contact, both patients and healthcare workers need not be in the same place while the test is being administered.

Saliva vs. Nasal Testing: Saliva test kits are readily available today; in fact, Vitagene is committed to providing 50,000 tests in the first month of service and scaling that number to 300,000 tests per month beginning in middle of May 2020. Additionally, Vitagene has partnered with supply chain manufacturers to provide the kits, which are manufactured in the U.S., supporting our economy and providing local employment.

Our new, efficient, and self-contained saliva collection kits using the EUA approved SDNA-1000 device, makes not only sample collection easy but sample transport as well, said Stephen Fanning. CEO of Spectrum Solutions. The proprietary preservation solution inactivates the virus once a biosample is collected to the point that we are able to suspend and stabilize the viral RNA transcripts for sensitive and specific qPCR testing by the lab. Another incredible benefit of our process is that we can help limit undue exposure making the testing for COVID-19 safer for everyone involved.

Convenient Access to Testing: Today, many communities do not have convenient access to hospitals or other testing facilities. This - combined with limited nasal test availability - has led to only ~1 percent of people being tested in the U.S. to date. In order to decrease and manage the health and economic risks of COVID-19, we need access to widespread testing. Now, anyone who thinks that he or she might have been exposed can go to Vitagene.com and start the process of being tested.

Our saliva-based test kit makes it possible for patients across the United States to have access to testing, not just those located near a hospital, clinic or testing facility. said Andrew Brooks, chief operating officer and director of technology development at the university's RUCDR Infinite Biologics lab. Millions of Americans, who until now might have to travel hours to their nearest testing location, can be sent a test by their doctor or clinic.

For more information or to order a Zero Contact COVID-19 test, please visit http://www.vitagene.com.

###

ABOUT VITAGENE

Headquartered in San Francisco, California, Vitagene Incorporated and its platform division 1health.io are focused on helping consumers improve their health and lifestyle. Vitagene leverages the latest science in machine learning and data analytics, as well as genomics, to provide actionable health plans to consumers. Vitagene keeps all data private and secure and does not share or sell data to third parties. Vitagene has a team of accomplished engineers, scientists and physicians dedicated to improving the health of its customers. To learn more, go to https://vitagene.com/.

ABOUT RUCDR

RUCDR Infinite Biologics, which is part of Rutgers' Human Genetics Institute of New Jersey, is the world's largest university-based cell and DNA repository. Its mission is to understand the genetic causes of common, complex diseases and to discover diagnoses, treatments and cures for them. The organization collaborates with researchers in the public and private sectors throughout the world, providing the highest quality bio-banking services and biomaterials, as well as scientific and technical support. For more information, please visit https://www.rucdr.org/.

ABOUT SPECTRUM SOLUTIONS AND SPECTRUM DNA

Headquartered in Salt Lake City, Utah, Spectrum Solutions and its medical device and services division, Spectrum DNA, focus on innovative, end-to-end product development, manufacturing, and global fulfillment solutions. With concentrated industry expertise, Spectrum DNA specializes in engineering innovative molecular diagnostic solutions that simplify the biosample collection process while offering donors complete physical and digital chain-of-custody. With on-site production facilities, we are a single-source provider of full-service medical device manufacturing, custom and private label packaging, kitting, and direct-to-donor global fulfillment. Our new biosample collection devices, patented technology, and services provide measurable process optimization, unprecedented efficiency, and unmatched global scalability. For more information, please visit https://spectrumsolution.com/.

Original post:

Vitagene Launches The First FDA Authorized Saliva based Zero Contact COVID-19 At Home Test - Business Wire

Genetics in focus after coronavirus deaths of siblings and twins – The Guardian

Amid the steady stream of stories on the lives lost to coronavirus are cases that stand out as remarkable. In the past month, at least two pairs of twins have died in Britain and two pairs of brothers, all within hours or days of each other. But do the deaths point to genetic factors that make some more likely than others to succumb to the disease?

Most scientists believe that genes play a role in how people respond to infections. A persons genetic makeup may influence the receptors that the coronavirus uses to invade human cells. How resilient the person is to the infection, their general health, and how the immune system reacts will also have some genetic component.

A team led by Prof Tim Spector, head of twin research and genetic epidemiology at Kings College London, has reported that Covid-19 symptoms appear to be 50% genetic. But Spector said more work is needed to understand which genes are involved and what difference they make to the course of the disease. We dont know if there are genes linked to the receptors or genes linked to how the infection presents, he said.

Identical twins Katy and Emma Davis, aged 37, died at Southampton general hospital last month. The sisters, who lived together, had underlying health problems and had been ill for some time before they contracted the virus. Another pair of twins, Eleanor Andrews and her sister Eileen, aged 66, died earlier this month. They too lived together and had underlying health conditions.

Two brothers from Newport, Ghulam Abbas, 59, and Raza Abbas, 54, died within hours of each other at Royal Gwent hospital. Another pair of brothers from Luton, Olume Ivowi, 46, and Isi Ivowi, 38, died within days of each other.

These deaths alert people to the fact that this could be genetic, but when people live together they share an environment as well, Spector said. The upshot is that twins who live together are more likely to have similar lifestyles and behaviours, from diet and exercise habits to how quickly they seek medical care. Twins are not generally less healthy than the wider population.

Twin deaths made headlines long before the coronavirus struck. When Julian and Adrian Riester died on the same day in Florida in 2011, a cousin of the twin Franciscan monks said it was confirmation that God favoured them. But Spector sees the hand of cold statistics at work. When you look formally at this, you see that twins rarely die at the same time, he said. There are billions of people on the planet. One in 70 is a twin and one in 200 is an identical twin.

Marcus Munafo, professor of biological psychiatry at Bristol University, said reports of twin deaths must be interpreted with caution. Twin deaths are unusual, which makes them newsworthy, but coverage can distort our perceptions. Salience bias refers to the fact that we tend to focus on information that stands out more, even if its not particularly relevant. So we need to be careful not to read too much into events that might stand out for reasons that are not actually related to the issue were interested in, he said.

When twins or siblings tragically die with Covid-19 that captures our attention, but that doesnt mean theres any particular reason to think twins or siblings are at greater risk.

View original post here:

Genetics in focus after coronavirus deaths of siblings and twins - The Guardian

‘An anvil on my chest’: What it’s like to have COVID-19 – LancasterOnline

There is a clinical list of COVID-19 symptoms that includes a dry cough, a fever and shortness of breath. And then there is how the disease actuallyfeels.It is like a lengthy hangover. An anvil on your chest. An alien takeover. It is like being in a fight with Mike Tyson.

More than 1 million people in the United States have become unwilling hosts to the coronavirus. We spoke with some who were sickened by it in many cases severely and have since recovered. In vivid terms, they described what it was like to endure this scary and disorienting illness.

Kinchen, 39, is a hairstylist in film production in Jersey City, New Jersey.

I woke up with a headache that was Top 5 of my life, like someone inside my head was trying to push my eyes out. I got a 100.6-degree fever.

The fever went away, and then I had nausea and a metallic taste in my mouth. I was hungry, and then the taste of food was unappetizing. I put some onions in the Instant Pot to saut. I put my face in the pot, but I couldnt smell the onions. I had the runs that lasted a couple of days.

My partner had a cough and shortness of breath. I would just start sobbing. I was totally freaked out. We got nasal swabs together, and it felt like they took a piece of our brain.

My partner got his results in 10 days. I got mine in 22.

Henry, 43, owns a public relations firm in Lathrup Village, Michigan.

It happened so fast. On Monday, I am in the parking lot of my allergists office with back pain and a cough that I thought was a sinus infection. On Saturday, I am in an ambulance headed to an emergency room.

Three days later, the doctors placed me in a medically induced coma and put me on a ventilator. I was in the hospital for two weeks.

Everything hurt. Nothing in my body felt like it was working. I felt so beat up, like I had been in a boxing ring with Mike Tyson. I had a fever and chills one minute my teeth are chattering and the next minute I am sweating like I am in a sauna.

And the heavy, hoarse cough, my God. The cough rattled through my whole body. You know how a car sounds when the engine is sputtering? That is what it sounded like.

My sister kept telling me to fight. All I could do was pray because my body had gone kaput.

Theres a list of coronavirus symptoms that many can now recite from memory. And then theres how it actually feels when you have it. (Thoka Maer via The New York Times)

Hammer,45, is an investigative reporter in New Orleans.

On Day 10, I woke up at 2:30 a.m. holding a pillow on my chest. I felt like there was an anvil sitting on my chest. Not a pain, not any kind of jabbing just very heavy.

When I told my wife I had this terrible pressure in my chest, she was like, Sit up. She made me some tea, and told me to cough.

Ive never really had a panic attack before, but Id never felt anything like this. I started to feel tingling in my fingers and my extremities, and Im thinking, This is a heart attack.

What I was experiencing was not extreme difficulty breathing it was panic about whether I had extreme difficulty breathing.

The thing that makes this so scary is that it is not linear, and the recovery is not linear.

Backlund, 72, is a retired French teacher in Anacortes, Washington.

Youre just so paranoid because all these weird symptoms come up that you havent read about. There is such a wide range of symptoms that you just keep waiting for the other shoe to fall. Youre always asking yourself, Is this the virus?

One of my friends started getting better and then she ended up dying. Several people started feeling better, and then took a dive. So, youre never really confident. For at least a couple of weeks, youre just not, because it could go awry.

I dont ever want to get this again. Its a pretty awful feeling. Its just so weird the way you swear that its mutating in your body every day, trying something else.

Backlund,73, is a psychiatrist in Anacortes, Washington.

It was just a loss of all energy and drive. There was no horizontal surface in my house that I didnt want to just lay down on all day long.

I didnt want to do anything. And my brain wasnt working very well. I was calling it the corona fog.

The LA Times actually sent a reporter and a photographer to our house and took a photograph of my wife at the piano and me with her singing. And I looked at the picture the next day, and I looked like Skeletor.

I just looked, and I thought, Ive got to start taking this seriously. I had to slap myself in the face and say, Youve got to start eating, and youve got to start drinking.

Miller,27, lives in Brooklyn, New York, and is a general manager at a food delivery platform.

It felt like a very long hangover. Smelling something, getting nauseous. The headache. The overall weakness that your body feels, but more severe.

Success! An email has been sent with a link to confirm list signup.

Error! There was an error processing your request.

It was chills on a level that Ive never experienced. Intense shivering. It was very hard to move. I had really intense body aches. It felt like I was in a UFC match and beaten up.

Doing anything other than laying in bed and sleeping was difficult. You had to be in the right position in order for your chest to not hurt. Or you had to be in a certain position in order to be able to take a full, comfortable breath.

Its like deep inside your chest. You feel it. Something is definitely inside of me, and Im definitely infected with something.

Chow,38, is an assistant professor of human genetics in Salt Lake City.

Walking made me lose my breath. I was just gasping. It felt like drowning.

I was in the ICU for my whole stay five days. The scariest part was being alone. My wife dropped me off at the ER and then was asked to leave. I didnt see her or my kids until I was discharged.

While in the ICU, I spent nights awake thinking about whether I was going to die. The first night they told me that they might have to intubate me, and I spent that whole night wondering whether I would ever see my family again.

The physical pain was mostly taken care of by drugs and oxygen. But the loneliness was real. The staff, too everyone was in PPE, so the interactions were very impersonal. I still dont know what any of the staff look like.

I did have great staff. They are amazing. Just didnt realize that seeing peoples faces was so important to feeling safe.

Taylor,71, is a geriatric social worker in New York.

My chest was tight, I was feverish, my appetite was going away and I had digestive issues. I lost 7 pounds. I called my doctor, and she said I needed to go to a hospital.

They put me in an isolation room, took my vitals, swabs and did a chest X-ray. It came back showing multifocal pneumonia. An ER doc said to me: You can still breathe on your own. Youre better off going home. If something changes, let me know, but we are about to run out of equipment in six days.

My fever broke two weeks after the emergency room visit. There were a couple of days when I thought, Im not going to make it this is taking over my body.

Im at the beginning of a very long recovery. Yesterday morning, I woke up feeling like I had difficulty breathing. The doctor said it was a scare, not a relapse.

Lat, 44, is a legal journalist and recruiter in New York.

I was barely able to walk or even stand, perhaps from not getting enough oxygen. But luckily, I had enough strength to make it to my nearest emergency room, which is where I belonged.

The intubation itself felt like a scene out of ER or Chicago Hope, one of controlled intensity. Attached to the ventilator, I slept for the next six days or so. I was later told that I woke up at various points, sometimes to try and remove the breathing tube or to write down questions. But I remember nothing of this.

When I woke up, I felt like Rip Van Winkle. It was as if those six days never happened. In my first conversation with my husband after extubation, I returned to the exact same topic we had been discussing right before I was intubated: whether he could bring a duffel bag of clothes and books to the hospital.

Wade, 44, lives in Chandler, Arizona, and works at a security and surveillance company.

Ive never felt so bizarre. My body felt like it was not my own. I had crazy back pain. Sometimes I felt like I couldnt move my shoulders.

I had a raw, dry cough, and the fevers spiked in the night. I have a C-section scar from 10 years ago that hurt again because I was coughing so much.

Everything I did left me feeling a little winded, and just the simple act of getting up and having a shower was tiring.

I had no appetite. I had to force myself to eat. I lost 9 pounds.

The only thing I can tell anyone else, especially people who dont know what they have and who are wondering, is: If you can get up and walk a little bit, walk two steps more. Just do whatever you can to keep moving.

Maer, 35, illustrator who is based in New York.

Its not like a common cold, where you feel a sore throat and sniffles. It just goes straight into your lungs, and you feel other symptoms coming from it.

My stomach pain was so bad, it felt like I had appendicitis. I also had a bad cough, shortness of breath and a heavy feeling in my lungs. I slept 19 hours a day, and it still didnt feel like enough.

When I started to recover, I lost my sense of smell and taste. It happened in one day.

The entire recovery process is two steps forward, one step back. You keep wondering the whole time, Is this it?

When it was over, I woke up feeling like a weight let go of me. It feels like I got a get-out-of-jail-free card now that I can move around outside a little more freely.

Subscribe today for only $2

' + submsgtxthtml + '

Get unlimited access to breaking news, ancestry archives, our daily E-newspaper, games and more.

Subscribe today for only $2

' + submsgtxthtml + '

Get unlimited access to breaking news, ancestry archives, our daily E-newspaper, games and more.

Subscribe today for only $2

' + submsgtxthtml + '

Get unlimited access to breaking news, ancestry archives, our daily E-newspaper, games and more.

Subscribe today for only $2

' + submsgtxthtml + '

Follow this link:

'An anvil on my chest': What it's like to have COVID-19 - LancasterOnline

Coronavirus may have spread to humans as early as October 2019 – study – The Jerusalem Post

A genetic study of samples from more than 7,500 people infected with COVID-19 suggests the new coronavirus spread quickly around the world after it emerged in China sometime between October and December last year, scientists said on Wednesday.

Scientists at University College London's Genetics Institute found almost 200 recurrent genetic mutations of the new coronavirus - SARS-CoV-2 - which the UCL researchers said showed how it is adapting to its human hosts as it spreads.

"Phylogenetic estimates support that the COVID-2 pandemic started sometime around Oct. 6, 2019 to Dec. 11, 2019, which corresponds to the time of the host jump into humans," the research team, co-led by Francois Balloux, wrote in a study published in the journal Infection, Genetics and Evolution.

Balloux said the analysis also found that the virus was and is mutating, as normally happens with viruses, and that a large proportion of the global genetic diversity of the virus causing COVID-19 was found in all of the hardest-hit countries.

That suggests SARS-CoV-2 was being transmitted extensively around the world from early on in the epidemic, he said.

"All viruses naturally mutate. Mutations in themselves are not a bad thing and there is nothing to suggest SARS-CoV-2 is mutating faster or slower than expected," he said. "So far, we cannot say whether SARS-CoV-2 is becoming more or less lethal and contagious."

In a second study also published on Wednesday, scientists at Britain's University of Glasgow who also analyzed SARS-CoV-2 virus samples said their findings showed that previous work suggesting there were two different strains was inaccurate.

JUST ONE VIRUS TYPE CIRCULATING

A preliminary study by Chinese scientists in March had suggested there may have been two strains of the new coronavirus causing infections there, with more of them more "aggressive" than the other.

But, publishing their analysis in the journal Virus Evolution, the Glasgow team said only one type of the virus was circulating.

More than 3.71 million people have been reported to be infected by the novel coronavirus globally and 258,186 have died, according to a Reuters tally.

Cases have been reported in more than 210 countries and territories since they were first identified in China in December 2019.

The genetic studies offer "fascinating" insights into the evolution of the virus, and emphasize that it is "a moving target with an unknown evolutionary destination," said Jonathan Stoye, head of the division of virology at Britain's Francis Crick Institute.

"All the evidence is entirely consistent with an origin towards the end of last year, and there's no reason to question that in any way," Stoye said.

The World Health Organization said the French case was "not surprising" and urged countries to investigate any other early suspicious cases.

Balloux's team screened the genomes of more than 7,500 viruses from infected patients around the world. Their results add to a growing body of evidence that SARS-CoV-2 viruses share a common ancestor from late 2019, suggesting this was when the virus jumped from a previous animal host into people.

Link:

Coronavirus may have spread to humans as early as October 2019 - study - The Jerusalem Post

Team reveals genomic history of ancient civilizations in the Andes – UC Santa Cruz

An international research team has conducted the first in-depth, wide-scale study of the genomic history of ancient civilizations in the central Andes mountains and coast before European contact.

The findings, published online May 7 in Cell, reveal early genetic distinctions between groups in nearby regions, population mixing within and beyond the Andes, surprising genetic continuity amid cultural upheaval, and ancestral cosmopolitanism among some of the region's most well-known ancient civilizations.

Led by researchers at Harvard Medical School and the University of California, Santa Cruz, the team analyzed genome-wide data from 89 individuals who lived between 500 and 9,000 years ago. Of these, 64 genomes, ranging from 500 to 4,500 years old, were newly sequencedmore than doubling the number of ancient individuals with genome-wide data from South America.

The analysis included representatives of iconic civilizations in the Andes from whom no genome-wide data had been reported before, including the Moche, Nasca, Wari, Tiwanaku and Inca.

"This was a fascinating and unique project," said Nathan Nakatsuka, first author of the paper and an MD/PhD student in the lab of David Reich in the Blavatnik Institute at HMS.

"It represents the first detailed study of Andean population history informed by pre-Colonial genomes with wide-ranging temporal and geographic coverage," said Lars Fehren-Schmitz, associate professor at UC Santa Cruz and co-senior author of the paper with Reich.

"This study also takes a major step toward redressing the global imbalance in ancient DNA data," said Reich, professor of genetics at HMS and associate member of the Broad Institute of MIT and Harvard.

"The great majority of published ancient DNA studies to date have focused on western Eurasia," he said. "This study in South America allows us to begin to discern at high resolution the detailed history of human movements in this extraordinarily important part of the world."

Attention on the Andes

The central Andes, surrounding present-day Peru, is one of the few places in the world where farming was invented rather than being adopted from elsewhere and where the earliest presence of complex civilizations in South America has been documented so far. While the region has been a major focus of archaeological research, there had been no systematic characterization with genome-wide ancient DNA until now, the authors said.

Geneticists, including several of the current team members, previously studied the deep genetic history of South America as a whole, including analysis of several individuals from the Andean highlands from many thousands of years ago. There have also been analyses of present-day residents of the Andes and a limited number of mitochondrial or Y-chromosome DNA analyses from individual ancient Andean sites.

The new study, however, expands on these findings to provide a far more comprehensive portrait. Now, Nakatsuka said, researchers are "finally able to see how the genetic structure of the Andes evolved over time."

By focusing on what is often called pre-Columbian history, the study demonstrates how large ancient DNA studies can reveal more about ancient cultures than studying present-day groups alone, said Reich.

"In the Andes, reconstruction of population history based on DNA analysis of present-day people has been challenging because there has so been much demographic change since contact with Europeans," Reich explained. "With ancient DNA data, we can carry out a detailed reconstruction of movements of people and how those relate to changes known from the archaeological record."

'Extraordinary' ancient population structure

The analyses revealed that by 9,000 years ago, groups living in the Andean highlands became genetically distinct from those that eventually came to live along the Pacific coast. The effects of this early differentiation are still seen today.

The genetic fingerprints distinguishing people living in the highlands from those in nearby regions are "remarkably ancient," said Nakatsuka, who will receive his PhD in systems, synthetic and quantitative biology in May.

"It is extraordinary, given the small geographic distance," added Reich.

By 5,800 years ago, the population of the north also developed distinct genetic signatures from populations that became prevalent in the south, the team found. Again, these differences can be observed today.

After that time, gene flow occurred among all regions in the Andes, although it dramatically slowed after 2,000 years ago, the team found.

"It is exciting that we were actually able to determine relatively fine-grained population structure in the Andes, allowing us to differentiate between coastal, northern, southern and highland groups as well as individuals living in the Titicaca Basin," said Fehren-Schmitz.

"This is significant for the archaeology of the Andes and will now allow us to ask more specific questions with regards to local demographies and cultural networks," said study co-author Jose Capriles of Pennsylvania State University.

Genetic intermingling

The team discovered genetic exchanges both within the Andes and between Andean and non-Andean populations.

Ancient people moved between south Peru and the Argentine plains and between the north Peru coast and the Amazon, largely bypassing the highlands, the researchers found.

Fehren-Schmitz was especially interested to uncover signs of long-range mobility in the Inca period. Specifically, he was surprised to detect ancient North Coast ancestry not only around Cusco, Peru, but also in a child sacrifice from the Argentinian southern Andes.

"This could be seen as genetic evidence for relocations of individuals under Inca rule, a practice we know of from ethnohistorical, historical and archaeological sources," he said.

Although the findings of genetic intermingling throughout the Andes correlate with known archaeological connections, they will likely prompt additional archaeological research to understand the cultural contexts underlying the migrations, said Nakatsuka.

"Now we have more evidence demonstrating important migrations and some constraints on when they happened, but further work needs to be done to know why exactly these migrations occurred," he said.

Long-term continuity

The analyses revealed that multiple regions maintained genetic continuity over the past 2,000 years despite clear cultural transformations.

The finding contrasts with many other world regions, where ancient DNA studies often document substantial genetic turnover during this period, said Reich.

The population structures that arose early on persisted through major social changes and on into modern societies, the authors said. The discoveries offer new evidence that can be incorporated alongside archaeological and other records to inform theories on the ancient history of different groups in the region.

"To our surprise, we observed strong genetic continuity during the rise and fall of many of the large-scale Andean cultures, such as the Moche, Wari and Nasca," said Nakatsuka. "Our results suggest that the fall of these cultures was not due to massive migration into the region, e.g., from an invading military force, a scenario which had been documented in some other regions of the world."

Two exceptions to the continuity trend were the vast urban centers that the Tiwanaku and Inca cultures called home. Rather than being fairly genetically homogeneous, the capital regions of these civilizations were cosmopolitan, hosting people from many genetic backgrounds, the team found.

"It was interesting to start to see these glimpses of ancestral heterogeneity," said Nakatsuka. "These regions have some similarity to what we see now in places like New York City and other major cities where people of very different ancestries are living side by side."

Cooperative authorship

The study included authors from many disciplines and many countries, including Argentina, Australia, Bolivia, Chile, Germany, Peru, the United Kingdom and the United States.

"This is an impressive interdisciplinary but, just as importantly, international collaboration," said study co-author Bastien Llamas of the University of Adelaide. "All worked very closely to draft this manuscript under the leadership of Fehren-Schmitz and Reich."

It was important to team up with local scientists who belong to communities that descend from the individuals analyzed in the study, Fehren-Schmitz said, and to obtain permission from and continually engage with indigenous and other local groups as well as local governments.

The analysis of DNA from ancient individuals can have significant implications for present-day communities. One concerns the physical handling of the skeletal materials, which might be sensitive to the groups involved.

The work provided opportunities to heal past wounds. In one case, a sample from Cusco, previously housed in the U.S., was repatriated to Peru. Other remains that had long ago been taken improperly from burial sites were able to be carbon-dated and reburied.

In the absence of pre-Columbian written histories, archaeology has been the main source of information available to reconstruct the complex history of the continent, said study co-author Chiara Barbieri of the University of Zurich.

With the study of ancient DNA, we can read the demographic history of ancient groups and understand how ancient and present-day groups are related, she said. The link with the genetic study of living populations opens a direct dialogue with the past and an occasion to involve local communities.

The researchers sought to deeply involve communities with the help of archaeologists from each area, said Nakatsuka. Their efforts included giving public talks about the study and translating materials into Spanish.

"We were really happy to have the summary and key findings of our paper translated and included as part of the Cell paper itself, to increase accessibility of our work," said Nakatsuka. "We hope future studies will do similar translations, including versions suitable for lay audiences for schools, museum exhibits and cultural organizations, which we are in the process of doing as well."

Original post:

Team reveals genomic history of ancient civilizations in the Andes - UC Santa Cruz

Regeneron Reports First Quarter 2020 Financial and Operating Results – BioSpace

TARRYTOWN, N.Y., May 5, 2020 /PRNewswire/ --

Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) today announced financial results for the first quarter of 2020 and provided a business update.

"Over 30 years, the Regeneron team has built a science and technology engine uniquely suited to address the COVID-19 pandemic and we are applying our signature passion, innovation, and drive to advance solutions. Our novel antibody cocktail, REGN-COV2, which is specifically-designed for both prevention and treatment, is expected to begin human studies in June and we are working in parallel to have large-scale quantities available by late summer," said Leonard S. Schleifer, M.D., Ph.D., President and Chief Executive Officer of Regeneron. "Beyond our COVID-19 efforts, we maintain our commitment to the many other patients with serious diseases who are counting on us. In the first quarter, we saw continued growth with EYLEA, Dupixent, and Libtayo in the U.S. driven by underlying demand despite the impact of the pandemic. Moreover, we continue to advance our broad immuno-oncology platform, including the PD-1 inhibitor Libtayo, for which we plan regulatory submissions this year in both non-small cell lung cancer and basal cell carcinoma, based on recent promising late-stage results."

"We believe our recent revision to the accounting presentation better reflects the nature of revenues earned and costs incurred and simplifies our financial reporting," said Robert E. Landry, Executive Vice President, Finance and Chief Financial Officer of Regeneron. "We were also pleased to close the Praluent restructuring transaction with Sanofi, which we expect to be accretive beginning in the second quarter of 2020."

Financial Highlights

($ in millions, except per share data)

Q1 2020

Q1 2019

% Change

Total revenues(4)

$

1,828

$

1,373

33

%

GAAP net income

$

625

$

461

36

%

GAAP net income per share - diluted

$

5.43

$

3.99

36

%

Non-GAAP net income(1)

$

771

$

518

49

%

Non-GAAP net income per share - diluted(1)

$

6.60

$

4.45

48

%

Business Highlights

Key Pipeline Progress

Regeneron has more than 20 product candidates in clinical development, including five marketed products for which it is investigating additional indications. Updates from the clinical pipeline include:

EYLEA (aflibercept) Injection

Dupixent (dupilumab)

Oncology Program

Praluent (alirocumab)

Evinacumab, an antibody to ANGPTL3

Pozelimab, an antibody to C5

REGN-EB3, a multi-antibody therapy to Ebola virus infection

COVID-19 Update

Business Development Update

In December 2019, the Company and Sanofi also announced their intent to restructure their antibody collaboration for Kevzara. The companies continue to assess potential terms of this restructuring in light of the recently launched clinical programs evaluating Kevzara in patients hospitalized with COVID-19.

First Quarter 2020 Financial Results

Effective January 1, 2020, Regeneron has implemented changes in the presentation of its financial statements related to certain reimbursements and other payments for products developed and commercialized with collaborators. The Company made these changes in presentation to better reflect the nature of the Company's costs incurred and revenues earned pursuant to arrangements with collaborators and to enhance the comparability of Regeneron's financial statements with industry peers. The change in presentation has been applied retrospectively. See Note (4) below for further information.

Revenues

Total revenues increased by 33% to $1.828 billion in the first quarter of 2020, compared to $1.373 billion in the first quarter of 2019.

EYLEA net product sales in the United States were $1.172 billion in the first quarter of 2020, compared to $1.074 billion in the first quarter of 2019. Overall distributor inventory levels for EYLEA in the United States remained within the Company's one-to-two-week targeted range.

Total revenues also include Sanofi and Bayer collaboration revenues(2) of $528 million in the first quarter of 2020, compared to $246 million in the first quarter of 2019. Sanofi collaboration revenue in the first quarter of 2020 included the Company's share of profits from collaboration antibodies (Dupixent, Praluent, and Kevzara) of $171 million, while Sanofi collaboration revenue in the first quarter of 2019 included the Company's share of losses from collaboration antibodies of ($28) million. The change in the Company's share of profits (losses) from collaboration antibodies was primarily driven by higher Dupixent profits.

Refer to Table 4 for a summary of collaboration revenue.

Operating Expenses

GAAP

%Change

Non-GAAP(1)

%Change

($ in millions)

Q1 2020

Q1 2019

Q1 2020

Q1 2019

Research and development (R&D)

$

584

$

486

20

%

$

527

$

427

23

%

Selling, general, and administrative (SG&A)

$

367

$

291

26

%

$

307

$

242

27

%

Original post:

Regeneron Reports First Quarter 2020 Financial and Operating Results - BioSpace

Scientists at Ben-Gurion University of the Negev Develop Anti-Coronavirus Surface Coating Based on Nanomate… – The Auto Channel

BEER-SHEVA, Israel, May 5, 2020 -- The coronavirus, SARS-CoV-2, which is responsible for the current COVID-19 pandemic, is transmitted between people mainly via respiratory droplets, but it is known that the virus remains stable on various surfaces for days. One of the first indications for this came from the Diamond Princess cruise ship, where active virus particles were found even 17 days after the ship was evacuated. In light of the possibility that the virus can spread through contaminated surfaces, it is important to be able to sterilize surfaces with high contamination potential, such as doorknobs, elevator buttons or handrails in public areas in general, and in hospitals and clinics in particular. However, current disinfectants are mainly based on chemicals such as poisonous sodium hypochlorite (bleach) or alcohol, both of which provide only a temporary measure until the next exposure to the virus.

Certain metals can be lethal, even in small quantities, for viruses and bacteria and are not poisonous to humans. In proof of concept experiments, in which also PhD students Yariv Greenshpan and Esti Toledo, and postdoc Guillaume Le Saux participated, the researchers assessed the effect of surfaces coated with nanoparticles of various metals on the infectivity of lentiviruses, which belong to the HIV family, in human cells. Findings show that surfaces coated with copper nanoparticles strongly block infection of the cells by the virus. These ongoing experiments show a huge potential for copper ions in preventing surface-mediated infection with SARS-CoV-2.

Based on these findings, the researchers are developing anti-viral coatings that can be painted or sprayed on surfaces. The coatings are based on polymers, which are the starting materials of plastics and paints, and contain nanoparticles of copper and other metals. The nanoparticles embedded in the polymer will enable controlled release of metal ions onto the coated surface. Studies show that these ions have a strong anti-viral effect, which can eradicate virus particles that adhere to the surface. Because the release of ions is extremely slow, the coating can be effective for a long period of time weeks and even months, and it will reduce the infectivity of the virus particles by more than 10-fold.

Josh Peleg, CEO, BGN Technologies, said, "The need to develop anti-viral coatings has greatly increased recently, with the SARS-CoV-2outbreak, and this need will likely remain high even after the pandemic ends, due to increased awareness. In addition, the product will be efficient as a general anti-viral and anti-bacterial coating. It can be applicable for medical settings, as an anti-pathogenic substance in places with increased risk of contamination, such as hospitals, but also for home use, and in public spaces such as schools, airports, public transportation and cinemas. We see a widespread and multidisciplinary academic commitment for finding solutions to currently medical and financial challenges as well as to the challenge of returning to normalcy once the pandemic wanes."

The research activity of Prof. Porgador and Dr. Schvartzman is part of the coronavirus research task force, founded by Prof. Daniel Chamovitz, President of BGU. To support this activity, it was decided to divert research funds in order to find rapid solutions for various challenges associated with the coronavirus pandemic. This invention received the support of the Israel Innovation Authority, in response to a call for proposals for coping with the coronavirus. The project is one of 27 proposals submitted to the Israel Innovation Authority by BGN Technologies, the technology transfer company of BGU, based on innovative and diverse inventions of researchers at BGU and the National InstituteforBiotechnologyin theNegev(NIBN) for the prevention, diagnosis and treatment of COVID-19.

Prof. Angel Porgador said, "The current coronavirus is transmitted not only through droplet spray but also via various surfaces that can convey the virus from one person to another. Furthermore, research shows that the virus remains viable on various surfaces for extended periods of time, of days and even longer. Therefore, there is a clear need for durable anti-viral coatings that can be sprayed or painted on surfaces, just like paint or varnish, and that will prevent viral transmission. These surfaces can include handles, buttons, railways or any other public surface that poses increased danger, in particular in places with a high concentration of potential carriers, such as hospitals or clinics. It is important to remember that we are developing coatings that will be effective not only against the coronavirus but also against other viruses, as indicated in our proof of concept experiments, and also against bacteria, so they will be relevant for a wide range of applications."

Dr. Mark Schvartzman commented, "While current surface disinfection methods rely mostly on substances that are poisonous for people, such as bleach, or on substances that evaporate readily being based on alcohol, the coating that we are developing is based on metals that are toxic for viruses or bacteria, but completely human friendly. It should be noted that until now using such metals for anti-viral applications has encountered significant challenges due to the nature of the metals, such as the tendency to oxidize and corrode. Nanoparticles provide a solution to these obstacles. Another advantage of nanoparticles is the large surface area to volume ratio, which results in an efficient anti-viral surface area using a relatively small amount of metal. Additionally, nanoparticles of anti-viral metal can be easily embedded in a polymer that can coat the relevant surfaces for extended periods of time."

About BGN Technologies

BGN Technologiesis the technology companyof Ben-Gurion University, Israel. The company brings technological innovations from the lab to the market and fosters research collaborations and entrepreneurship among researchersand students. To date, BGNTechnologieshas established over 100 startup companiesin the fields of biotech, hi-tech, and cleantech as well as initiating leading technology hubs,incubators, and accelerators.Over the past decade, it has focused on creating long-term partnerships with multinational corporations such as Deutsche Telekom, Dell-EMC, IBM, PayPal, Cincinnati Children's Medical Center, Merck, Sigma and Bayer, securing value and growth for Ben-Gurion University as well as for the Negev region.For more information, visit the BGN Technologies website.

About NIBN

The National Institute for Biotechnology in the Negev Ltd. (NIBN), a unique research institute located within Ben-Gurion University of the Negev (BGU), is the first self-organized, independent research entity established under the auspices of a university in Israel.

The NIBN was established as a company in November 2009 through a trilateral agreement between the Israeli Government, Mr. Edgar de Picciotto, and Ben-Gurion University.

The mission of the NIBN is to conduct multi-disciplinary applied research guided by a clear biotechnology vision, to bridge the gap between basic and applied innovative research, and facilitate the commercialization of novel ideas and technologies developed by NIBN researchers.

Research at the NIBN is focused in several key areas: cancer, infectious diseases, autoimmune and metabolic diseases, human genetic disorders, neurodegenerative diseases, and applied biotechnology, including AgBio. The decision to focus on these topics combines existing strengths and resources unique to the NIBN and BGU. For more information, visit theNIBN website

Media Contact:

Tsipi HaitovskyGlobal Media LiaisonBGN TechnologiesTel: +972-52-598-9892E-mail: [emailprotected]

SOURCE BGN Technologies

Here is the original post:

Scientists at Ben-Gurion University of the Negev Develop Anti-Coronavirus Surface Coating Based on Nanomate... - The Auto Channel

COVID-19 and food security – Fitzwilliam College, University of Cambridge

This article is a commentary by Fitzwilliam Honorary Fellow ProfessorM S SwaminathanFRS (PhD Botany 1950), as told to his daughter Nitya Rao.

I started my post-graduate work on potato in 1947 at the Indian Agriculture Research Institute (IARI), New Delhi. Growing up in Tamil Nadu, I had witnessed the damage to the potato crop by a disease called late blight (caused by Phytophthora infestans) in the Nilgiri Hills. Potato was a very important crop here, and its destruction led to considerable distress for the local people, as this coincided with World War II, when rice too was in short supply, due to the lack of imports from Burma (Myanmar). While many scientists were already working on wheat and rice, potato was at that time under-researched in India, perhaps because of its geographical concentration in the hills of southern India and the eastern Himalayas.

I continued my research on potato at the University of Wageningen, the Netherlands, in 1949. I learnt that during World War II, potato became the major food crop in Europe, leading to the abandonment of traditional crop rotations, and subsequently to the problem of resistance to the golden nematode in the polder lands. Potato is prone to a range of viruses, bacterial and fungal infections, and my work therefore focused on developing varietal lines resistant to pests and diseases.

I moved to Cambridge in 1950 and continued my PhD work on potato pests and diseases with Dr H WHoward. My work relied on inter-specific hybridisation, a technique that came to be increasingly used after the Irish potato famine of the 1840s. When I studied the question of why the Irish experienced such a serious epidemic pest, the late blight, I found the main reason to be the cultivation of a single variety. With no genetic variability, the potato became vulnerable to the rapid spread of disease. Fortunately, in Cambridge, there was a large collection of tuber-bearing potato (Solanum) species from Latin America, which provided valuable genes for developing lines of resistance to several serious stresses and diseases.

I published a paper in the American Potato Journal in 1951 on the importance of genetic diversity and variability, and this in fact, led to the US Department of Agriculture asking me to help them establish a potato collection at Sturgeon Bay, University of Wisconsin, Michigan. Here, one of the crosses I developed, between S. tuberosum and S. acaule, a species which grows at high altitudes in Peru, resulted in the frost-tolerant variety Alaska Frostless. Through my research, published in Biblographia Genetica, I demonstrated clearly that if we have enough genetic material in hand, we will be able to make new lines, resistant to disease or bearing specific characteristics.

Over a period of thousands of years, there have been mutations or changes to crops through a process of natural selection, that is, certain strains that are resistant to disease, survive. But once a plant becomes a crop, there is a process of human selection too that comes into play. So, potato breeders, for instance, selected strains of potato resistant to the late blight, after the Irish famine. For the coronavirus, part of the process of developing a vaccine is based on mapping the genetic traits of the virus. While nature conserves genes, human selection additionally takes account of quality, be if of food, or of human life itself.

The importance of genetic diversity and biodiversity cannot be emphasised enough in the context of food security. During the Bavarian war of succession in the late 18th century, there was a period called kartoffelkreig or the potato war. The potato crop was damaged by blight, and as the two armies had nothing to eat, while there were only minor skirmishes, thousands of soldiers died of starvation and disease. In Europe, this too emphasised the need for varietal diversity of potato, the main staple food. A single genetic strain, like the present COVID-19 pandemic, can lead to severe distress, in the absence of resistant strains.

Coming to the lessons in todays context, and for the future of food and agriculture in India, I again draw a parallel with the Irish potato famine. As the famine led to hunger and starvation, it also led to epidemics of infectious diseases. When people are starving, they are more prone to disease. On television, we find stories of migrants reporting that they might starve to death due to lack of food even if not due to the coronavirus. A basic problem we are confronting today is of inadequate food intake, especially for the poor and those already malnourished. This can affect immunity, but also longer-term nutrition and health.

There are two key lessons for food and nutrition security and agriculture more broadly. On the production side, the main moral lesson is to promote genetic heterogeneity. The late blight devastated the entire potato crop, leading to severe famine and loss of many lives. This implies the need to preserve and cultivate a range of varieties, be it of potato or other crops. In India, we are fortunate to have enough diversity of crops, so if one fails, there is always another crop.

However, at the present moment there is an issue of availability of suitable seed varieties, given that many of the standing crops have not been harvested. The government needs to ensure that seeds in adequate quantity and for a diversity of farming systems are made available to the farmer preparing now for the kharif sowing.

In the 1960s, I had started the first seed village in Jaunti in Delhi state. The idea was that the whole village produce seed to meet farmers demand, but also ensure farmers control over the varieties. Later known as participatory breeding, scientists from IARI and farmers worked together to develop characteristics there were desirable, both in terms of production yields, but equally taste and colour preferences. Farmers at that time preferred amber coloured wheat to red varieties such as Sonora, which we had acquired from Mexico, for making chapattis.

We experimented with vegetable seeds production villages in Tamil Nadu, in the early years of the M.S. Swaminathan Research Foundation (MSSRF) and while entire villages have not taken this up, there remain clusters of farmers who produce seeds for pulses, vegetables and so on. It is even more important now to support local production of seeds that ensure genetic variability. We need to specifically identify donor genes that can help develop varietal lines resistant to a range of pests, pathogens and weeds.

The other important lesson is in the field of post-harvest technology. In the present context of corona, and the national lockdown, farmers distress (especially for those producing horticultural crops) is intensified due to lack of post-harvest processing, storage, value addition and marketing mechanisms. The Amul model, supported by the National Dairy Development Board (NDDB), has demonstrated that even during the present COVID-19 crisis, the livelihoods of small farmers, in this case, milk producers, can be secured through collective action that ensures procurement, storage, transportation, value addition and marketing.

It is time that the National Horticultural Board is supported to play a proactive role similar to the NDDB. Even food crops are likely to get infected with fungi, aflatoxins and micro-toxins, in the absence of proper post-harvest storage and processing. In fact, following the Irish potato famine, in addition to potato collections to preserve genetic diversity, measures to protect both seed and food were put in place including modern storage systems.

Finally, during the Irish potato famine, people did not know what had happened, there was no information available till after the event. In India today, we have the advantage of excellent information and communication technology, which needs to be put to full use to reach the unreached with appropriate and timely information. There are several small initiatives towards this end. While the government machinery is providing good information on dealing with COVID-19, at the same time, we need to help our farmers and small producers deal with the threat of pest and disease in their farming systems too. For instance, close to a 100 farmers joined a plant clinic run by MSSRF, online for the first time.

The Green Revolution helped us move from a ship to mouth existence to a commitment to the right to food. Our food stocks need to be used to ensure the food security of the poor and hungry many of them farmers who have contributed to the building of this stock. This crisis is a time to recognise and strengthen our farming community women and men.

Citation:

Swaminathan, M.S. (1951) Notes on induced polyploids in the tuber-bearing solanum species and their crossability with s.tuberosum. American Potato Journal. 28: 472-482.

Swaminathan, M.S andHoward H.W (1953) The cytology and genetics of the potato (solanum tuberosum) and related species. Bibliographia Genetica. 16: 1-192.

M.S. Swaminathan is an eminent agricultural scientist, the winner of the World Food Prize, and was the Chairman of the National Commission on Farmers. Nitya Rao is Professor of Gender and Development at the School of International Development, University of East Anglia, the UK.

This article originally featured onMongabay-India.

Read the original:

COVID-19 and food security - Fitzwilliam College, University of Cambridge

Millions of animals are being euthanized due to meat plant closures – Vox.com

Across the country, meatpacking plants are shutting down over coronavirus outbreaks among staff. Since the start of April, huge meat firms like Tyson Foods, Smithfield Foods, JBS USA Holdings, and Cargill have closed at least a dozen pork, beef, and chicken processing plants, per the Wall Street Journal. At least 3,400 people in meatpacking facilities have tested positive, and at least 17 have died, the Midwest Center for Investigative Reporting estimates.

And because of the intense concentration of the meatpacking industry, these facilities account for a massive share of Americas overall meatpacking capacity. As much as 40 percent of Americas pork-packing capacity is currently idle, by one estimate.

This wont necessarily lead to meat shortages, as Nicole Narea explains (though it might cause spot shortages at your local grocery store). But it has severe consequences for the animals left on farms across the country.

Pork and poultry production (and to a lesser extent beef production) is done on a just-in-time basis, explains Jayson Lusk, an agricultural economist at Purdue. Farms typically operate on the assumption that theyll be able to send off mature hogs to slaughter so that hogs still being grown have room to live; there isnt much excess capacity if the mature hogs have to stick around due to meatpacking bottlenecks.

If the finished pigs, who weigh about 280 lbs, are unable to head to the packing plant, there is no room in the barn to receive the new batch of pigs from the nursery, Lusk explains in a recent blog post. If the nursery isnt vacated, there is no room for the piglets. All the while, new piglets are being born with nowhere to go.

That means that the number of excess hogs on pig farms is growing rapidly. We have a national pork processing capacity of about 500,000 head per day, Lusk writes. Latest data suggests that because of plant closures and slowdowns, we are processing about 40% fewer pigs, which means an extra 500,000*0.4 = 200,000 pigs that are left on the farm. Every. Single. Day. Do that for 5 days, and thats 1 million excess pigs left on the farm. This holds at both small and large farms; these problems are faced by producers at all levels.

So farms across the country are facing a massive dilemma: What do we do when there are millions of additional animals we dont have space, labor, or food to care for? There are several options available, but they boil down to three big strategies:

Youre having to choose between amazingly bad options for protecting their welfare, or making the incredibly difficult choice to euthanize them all because there are fates worse than death, says Candace Croney, a professor of animal sciences at Purdue and an expert on animal welfare on farms.

Some farms are already taking the extreme step of euthanasia (a term some might argue is a misnomer since their killing isnt strictly for the animals benefit in this case). Allen Harim, a poultry processor, has announced it will euthanize 2 million chickens in Delaware and Maryland. JBSs pork plant in Worthington, Minnesota, has reopened to euthanize pigs from local hog farms, not to process them for sale. A representative for the Minnesota Pork Producers Association told the Star-Tribune he expects 60,000 to 80,000 hogs will be put down this week in Minnesota alone.

This kind of effort isnt unprecedented. In 2015, an avian influenza outbreak led to the US Department of Agriculture assisting in the euthanizing of 31.5 million birds in Iowa. But the animal welfare costs of the Covid-19 outbreak are relatively underpublicized, and severe. The costs on human farmers forced to euthanize animals are severe as well. It takes a significant emotional and psychological toll on the people who have to do it, Croney says. Theyll try to avoid it if at all possible. Its devastating to make these kinds of decisions and they have some lasting psychological repercussions.

Because animal agriculture in the US is a highly competitive industry, the life cycles of the livestock and poultry being raised and slaughtered are tightly regulated for maximum efficiency. A pig typically goes through a 292- to 311-day (about 9 1/2 to 10 1/2 months) life cycle from a female pigs impregnation through to slaughter for market, the National Pork Board explains.

That process involves four separate types of enclosures for the animals: gestation facilities for pregnant pigs; farrowing facilities for mothers (sows) and their newborns; nurseries for piglets after theyve been weaned; and finishing barns for pigs as they grow up to market size.

Each of those facilities is usually filled to maximum capacity, for efficiencys sake. That makes a bottleneck like closed processing plants immensely challenging for farmers. If they cant offload mature pigs to meatpacking plants (which usually slaughter and dismember the finished pigs), then they have nowhere to place pigs coming up from nurseries. If they leave pigs in their nurseries, then the youngest piglets just weaned off their mothers have nowhere to go. If those piglets go nowhere, then pregnant pigs have nowhere to go once they give birth. A blockage at one point in the process causes problems throughout the whole process.

Poultry faces a similar problem, though given that meat chickens lifespans are typically only 6 to 8 weeks, farmers have a bit more flexibility and fewer built-in time costs. Pasture-raised cattle are more flexible since you can add additional cattle to the pasture, but they face overcrowding concerns as well.

So, what can farms do if theyre faced with excess animals? Croney notes that they can try to slow the growth of animals, perhaps by reducing food given to them. But this comes with immense costs. You can curtail growth by curtailing how much you feed them, but then you have animals that are hungry and crowded, which sets them up for competition around food, which can lead to injury and death, she notes.

Pork and especially chicken plants already dont offer much space to their animals. A 2011 survey found that pigs got on average 7.2 square feet each; the National Chicken Council reports that standard industry practice is to give about 0.8 square feet for each chicken, or barely more than a standard sheet of paper. Overcrowding due to Covid-19 could entail offering them even less space.

Farmers can theoretically place excess animals outdoors but this might be an even worse option. In order to let them have access outdoors, much less to house them outdoors, you have to have a certain level of setup and protections for them, Croney explains. The types of fencing, shade, water access, protection from predators and inclement weather youd have to have that set up and reworked. If you have a farm with a couple thousand animals, that would be incredibly difficult to do. You certainly dont have labor to spare to help you do that, and those systems require much more intensive oversight and management.

For chickens, there are particular concerns apart from overcrowding or outdoor dangers that come into play when mature chickens are no longer being slaughtered. Broiler chickens, or chickens bred for meat as opposed to egg-laying hens, have been bred to be so large that if theyre allowed to live longer than planned, they suffer from animal welfare problems because they could be too large relative to their ability of legs to withstand the weight, Lusk explains. You dont have near that problem with pigs or cows. The animal welfare problem with pigs is the backing-up issue, and the animal welfare problem with chickens is them getting too big.

Given these difficulties, its not hard to see why some farms are already opting for euthanasia. But that comes with its own difficulties. Processing plants are supposed to render animals insensible and unable to feel pain before slaughtering them, and to use calming practices that make slaughter as minimally stressful as possible. As sad as even that death is, the process is typically smooth and the animals shouldnt be able to anticipate what is happening, Croney says. With mass euthanasia and limited personnel, that orderly, one-by-one, careful, generally consistent process is difficult, sometimes impossible to achieve, which is why no one ever wants to be in that position.

Croney notes euthanasia can take many forms, from gassing to bolt guns to straight-up gunshots; the latter creates obvious noise problems and is difficult to scale. Especially if people are using physical methods with captive bolt or gunshot, people are becoming stressed themselves and having to hurry, Croney says. That may mean that things are not done as accurately or humanely.

Then theres the problem of disposal. Without processing plants that can dismember animals, ship out usable meat, and dispose of the rest, its not obvious what farmers can do with the animals they euthanize. JBS, a massive pork processor, is sending hogs sent to it for euthanasia by hog farmers to landfills (basically mass graves) or external meat rendering plants. As processors like JBS shut down facilities, though, more and more of these tasks may be taken up by the farms themselves, not meatpackers and meat processors. That leaves disposal as more of an open question, with options like burial on the farm itself presenting themselves.

The entire situation is tragic, Croney concludes, and not just for animals. Whatever our stances on meat-eating, this is a time to be a little sensitive. There are people who are incredibly depressed, who are struggling, who really do care about their animals, and this is incredibly hard for them. The human toll this takes is not often talked about.

Support Voxs explanatory journalism

Every day at Vox, we aim to answer your most important questions and provide you, and our audience around the world, with information that has the power to save lives. Our mission has never been more vital than it is in this moment: to empower you through understanding. Voxs work is reaching more people than ever, but our distinctive brand of explanatory journalism takes resources particularly during a pandemic and an economic downturn. Your financial contribution will not constitute a donation, but it will enable our staff to continue to offer free articles, videos, and podcasts at the quality and volume that this moment requires. Please consider making a contribution to Vox today.

Excerpt from:

Millions of animals are being euthanized due to meat plant closures - Vox.com

Distress at dying law plans in Tasmania – The Catholic Weekly

Reading Time: 3 minutesArchbishop Julian Porteous addresses media in Tasmania in 2017. PHOTO: Archdiocese of Hobart

Pro-life leaders are appalled that an assisted suicide campaign in Tasmania will continue with minimal delay despite the coronavirus pandemic.

Independent MLC Mike Gaffney will introduce his private members bill to the Parliaments upper house in September, after it was originally slated for August.

The End-of-Life Choices (Voluntary Assisted Dying) Bill 2020 it is the most extreme assisted dying regime the country has yet seen. It would allow assisted suicide for those who are not terminally ill, not currently experiencing physical or emotional suffering in relation to their medical condition, and without the need to be seen by a specialist doctor.

It comes as New Zealand also prepares to go ahead with its planned referendum on euthanasia in September.

When the elderly and vulnerable are isolated and anxious, while the government and community fight to protect and save their lives, how can (Mr Gaffney) promote assisted suicide? said Australian Christian Lobbys acting Tasmanian director Christopher Brohier.

He should learn from NSW Nationals leader John Barilaro, who pulled Nationals MP Trevor Khan into line for promoting assisted suicide during the bushfire crisis earlier in the year.

We need consistent messaging from Tasmanian MPs that elderly vulnerable lives are worth saving

Whilst Mr Gaffney is saying COVID-19 responses will take precedence, he should cancel his campaign for assisted suicide indefinitely. We need a statewide and national united front in addressing the COVID-19 crisis. We also need consistent messaging from Tasmanian MPs that elderly vulnerable lives are worth saving.

The Tasmanian Australian Medical Association (AMA) is also strongly opposed to the push. A doctors role is to care for patients, to treat them, provide comfort and support, and to relieve suffering, but not to intentionally end a patients life, Tasmanian AMA President Professor John Burgess told media.

Professor Burgess also said the timing of the Bills introduction this year is inappropriate, as the circumstances around the pandemic impede an effective consultation process.

The Archbishop of Hobart Julian Porteous has repeatedly said that the sick and dying need to be treated with the best possible care and compassion and warned that any assisted suicide regime would put vulnerable people at risk. There is simply no safe way of legislating for euthanasia and assisted dying that does not fundamentally threaten the lives of the vulnerable in our society, he told The Catholic Weekly.

Peoples suffering and pain should be relieved in a way consistent with the dignity of human life through the use of palliative care in the final phase of their life.

The Bill lists disease, illness, injury, or medical condition, of the person that is serious, incurable and irreversible as relevant medical conditions under which Tasmanian residents over 18 would access the regime.

A person would be eligible if they had intolerable suffering caused by the relevant medical condition, or its treatment, or anticipation of the suffering that may arise from these.

The Tasmanian Parliament has voted down similar bills three times already, most recently in 2017. This is the first to be introduced and debated in the Upper House.

Mr Gaffney said he is confident it will be passed into law this year. It if is, it would make Tasmania the third Australian state with an assisted suicide regime after Victoria and Western Australia which passed their laws in 2017 and 2019 respectively. The primary purpose for me for this Bill is to give people a choice, Mr Gaffney told media.

Related:

Watch hard-hitting new euthanasia awareness campaignMonica Doumit: From bad to worse on euthanasiaNick Goiran: Elephant in the euthanasia room

Original post:

Distress at dying law plans in Tasmania - The Catholic Weekly

Murphy Oil defers two exploration wells offshore Mexico to 2021 – Offshore Oil and Gas Magazine

The company's Gulf of Mexico assets.

(Courtesy Murphy Oil Corp.)

Offshore staff

EL DORADO, Arkansas Murphy Oil Corp. has revised its 2020 budget to a midpoint of $740 million, the company revealed in its latest results statement.

The company has reduced its capital allocation to about $335 million for its offshore assets, with 94% planned for the Gulf of Mexico and the remaining 6% for offshore Canada.

Revisions from the original plan include adjusting the three-well rig program at Front Runner to two wells with the third well deferred to a later date, no longer drilling or completing certain operated wells and non-operated projects, and shifting timing of other plans. Expenditures for the St. Malo waterflood and the Khaleesi / Mormont and Samurai projects are still planned for 2020. Canada offshore spending remains budgeted for development drilling.

It has adjusted its 2020 exploration plans to a one-well non-operated program, deferring the two exploration wells offshore Mexico to 2021.

In 1Q, the A4 well in Green Canyon block 338 in the Gulf of Mexico came online. The company is evaluating near-field exploitation opportunities, as it encountered more than 250 ft (76 m) of net pay in the well. The well, the first in the Front Runner rig program, has outperformed expectations with a gross peak rate of about 7,000 boe/d.

The company also completed the subsea equipment repair at the Neidermeyer field in Mississippi Canyon block 209.

Construction of the Kings Quay FPS continues to progress, the company said. Transaction documentation with ArcLight Capital Partners, LLC and other parties is moving forward, and it expects to close the transaction in 2Q 2020.

In 2Q, EnVen Energy Ventures, LLC is expected to spud the Mt. Ouray well in Green Canyon block 767. Murphy holds 20%.

The company is also closing its corporate headquarters in El Dorado, Arkansas and office in Calgary, Alberta. It is relocating its corporate headquarters to Houston.

05/08/2020

See more here:

Murphy Oil defers two exploration wells offshore Mexico to 2021 - Offshore Oil and Gas Magazine

‘Late to the party’ France finally set to join offshore wind big-league: Rystad – Recharge

Late to the party France is set to leapfrog other European offshore wind nations as it hits 7.4GW in operation by 2030, said analysts at Rystad Energy.

That would make France whose plans include a major push into floating wind Europes number-four offshore wind market, Rystad said.

The Norwegian analyst group said French offshore wind is now moving ahead at full steam despite any potential cost and supply chain issues resulting from the Covid-19 pandemic.

The 7.4GW estimate would surpass the 2030 targets for other well-established European offshore wind countries such as Belgium and Denmark, which have 4GW and 5.3GW goals respectively.

It would place France behind only the UK, which is aiming to have 40GW of offshore wind capacity, Germany (15GW-20GW), and the Netherlands (11.5GW).

Rystad said France is expected to retain its position well into the 2030s with an additional 5GW of capacity lined up for planned tender rounds between 2024 to 2028.

Regulatory delays mean Frances first 1GW of fixed-bottom offshore wind farms are only now gearing up for construction, despite being awarded in tenders held as long ago as 2012.

Although France has been quite late to the party compared to several of its western European counterparties, recent developments suggest the country is now picking up the pace. Frances target for operational capacity is 2.4GW in 2023, a target expected to be reached through the completion of already awarded projects, said Alexander Fltre, Rystads vice president and product manager of offshore wind.

The first part of the plan will be kicked off this year with a tender for 1GW of bottom-fixed capacity in the French parts of the English Channel off the coast of Normandy, covering a development area called Manche Est Mer du Nord.

In 2021 to 2022 another 0.5GW to 1GW of bottom-fixed capacity will be put up for tender off southwest France, in an area named Sud-Atlantique. A part of this southern Atlantic tender may cover the already proposed 0.5GW to 1GW offshore wind project outside le dOlron, an island in the Poitou-Charentes region.

The French government also plans to organise three separate floating wind tenders in 2021-2022, each with a capacity of 250 MW. The first, in 2021, will be in the southern waters off Brittany (Bretagne Sud), while the other two in 2022 are planned for areas in the Mediterranean.

Another 1GW of bottom-fixed offshore wind will be tendered in 2023, at a location which has yet-to-be-determined.

From 2024 to 2028 the French government plans to award 1GW of capacity per year, which can be bottom-fixed, floating, or a mix of both. The amount of floating capacity to be awarded will depend on its cost competitiveness compared to the more established bottom-fixed alternative.

The French wind association FEE said last month that while the overall offshore wind target doesnt live up to Frances massive potential, that the governments plan puts the country in a global leadership position when it comes to the development of floating wind.

View post:

'Late to the party' France finally set to join offshore wind big-league: Rystad - Recharge

Dominion Energy remains on schedule to build largest offshore wind project in United States – Transmission & Distribution World

Form Energy, a company developing ultra-low-cost, long-duration energy storage for the grid, signed a contract with Minnesota-based utility Great River Energy to jointly deploy a 1MW / 150MWh pilot project to be located in Cambridge, Minnesota. Great River Energy is Minnesota's second-largest electric utility and the fifth largest generation and transmission cooperative in the U.S.

This system will be the first commercial deployment of Form Energy's proprietary long-duration energy storage system. Form Energy's aqueous air battery system leverages some of the safest, cheapest, most abundant materials on the planet and offers a clear path to low-cost, long-duration energy storage.

The project with Great River Energy will be a 1-MW, grid-connected storage system capable of delivering its rated power continuously for 150 hours, longer than the two to four hour usage period common among lithium-ion batteries being deployed at utility-scale today. This duration allows for a fundamentally new reliability function to be provided to the grid from storage, one historically only available from thermal generation resources.

Leading up to the decision to deploy the pilot project, Form Energy conducted a portfolio optimization study of Great River Energy's system characteristics with Formware, a proprietary software analytics platform design to help energy planners model future grids. Formware was purpose-built to model high penetration renewables at the system level and determine how all types of storage enable cost-effective renewable energy integration. The tool helps planners reduce exposure to extreme weather events and minimize uncertainty around commodity prices under a variety of future grid scenarios. "To understand how best to make the energy transition, new analytical tools are needed, and Formware allowed us to work with GRE to systematically and thoroughly understand the value that our assets can bring to their system," said Marco Ferrara, SVP Analytics and Business Development for Form Energy.

"Great River Energy is excited to partner with Form Energy on this important project. The electrical grid is increasingly supplied by renewable sources of energy. Commercially viable long-duration storage could increase reliability by ensuring that the power generated by renewable energy is available at all hours to serve our membership. Such storage could be particularly important during extreme weather conditions that last several days. Long-duration storage also provides an excellent hedge against volatile energy prices," said Great River Energy Vice President and Chief Power Supply Officer Jon Brekke.

"Our vision at Form Energy is to unlock the power of renewable energy to transform the grid with our proprietary long-duration storage. This project represents a bold step toward proving that vision of an affordable, renewable future is possible without sacrificing reliability," noted Mateo Jaramillo, CEO of Form Energy.

"We are thrilled to have Great River Energy as the first strategic utility partner to deploy Form's first bi-directional power plant. Their forward-leaning and innovative approach to their grid transition makes them a perfect partner," said Ted Wiley, President of Form Energy.

Great River Energy announced plans to transition its portfolio of power supply resources in the coming years. The electric cooperative plans to phase out its remaining coal resources, add significant renewable energy, and partner with Form Energy on its grid-scale battery technology.

"Long duration energy storage solutions will play an entirely different role in a clean electricity system than the conventional battery storage systems being deployed at scale today. Lithium-ion batteries are well suited to fast bursts of energy production, but they run out of energy after just a few hours. A true low-cost, long-duration energy storage solution that can sustain output for days, would fill gaps in wind and solar energy production that would otherwise require firing up a fossil-fueled power plant. A technology like that could make a reliable, affordable 100% renewable electricity system a real possibility," said Jesse Jenkins, an assistant professor at Princeton University who studies low-carbon energy systems engineering.

Founded in 2017, Form Energy has raised over $50 million in funding. The company is backed by investors Eni Next LLC, MIT's The Engine, Breakthrough Energy Ventures, Prelude Ventures, Capricorn Investment Group and Macquarie Capital.

Originally posted here:

Dominion Energy remains on schedule to build largest offshore wind project in United States - Transmission & Distribution World