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Agricultural Nanotechnology Market 2020: Applications, Types and Growing Trends in Market, Gross Margin and Market Share 2025 – CueReport

Posted on July 21, 2020 by Danzig

Global Agricultural Nanotechnology Market 2020 by Manufacturers, Type and Application, forecast to 2025 is a comprehensive study that delivers market data with characteristics, era, and market chain with analysis and developments and increases. The report offers a prompt point of view on the Agricultural Nanotechnology market, explaining the industry supply, marketplace demand, value, competition, and its analysis of key players with industry forecast from 2020 to 2025. It speaks about the market major leading players, market size over the forecast period from 2020 to 2025.

The Agricultural Nanotechnology market report offers significant information regarding this business vertical. As per the document, the market is estimated to record considerable growth as well as amass notable gains during the estimated timeframe.

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The study elaborates the major trends of Agricultural Nanotechnology market while evaluating the growth opportunities, industry size, volume of sales and revenue predictions. The report also provides a detailed assessment of the various segmentations and their respective impact on the overall market outlook. Moreover, it analyzes the effect of COVID-19 pandemic on the growth rate as well as remuneration generation of the market.

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As per the regional scope of Agricultural Nanotechnology market:

Other data specified in the Agricultural Nanotechnology market report:

Some of the key questions answered in this report:

What will the Agricultural Nanotechnology market growth rate, growth momentum or acceleration market carries during the forecast period?

Which are the key factors driving the Agricultural Nanotechnology market?

What was the size of the emerging Agricultural Nanotechnology market by value in 2020?

Which region is expected to hold the highest market share in the Agricultural Nanotechnology market?

What will be the size of the emerging Agricultural Nanotechnology market in 2025?

What trends, challenges and barriers will impact the development and sizing of the Global Agricultural Nanotechnology market?

What are sales volume, revenue, and price analysis of top manufacturers of Agricultural Nanotechnology market?

What are the Agricultural Nanotechnology market opportunities and threats faced by the vendors in the global Agricultural Nanotechnology Industry?

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NVIDIA and University of Florida Release New AI Curriculum Spanning All Educational Disciplines – Motley Fool

Posted on July 21, 2020 by Danzig

The University of Florida (UF) wants to be a top-five public university, and it's turning to artificial intelligence (AI) to meet that goal. Back in May 2020, UF was the first higher education institution in the U.S. to receive NVIDIA's (NASDAQ:NVDA) newest DGX A100 data center computing unit. Just a few months later, the AI initiative is expanding in grand fashion via a $50 million gift and an additional $20 million invested by UF to help the university build the most powerful supercomputer system in the academic world.

UF's new $70 million system (which builds upon its existing HiPerGator supercomputer) should be up and running by early 2021 and will be able to handle 700 petaflops per second. A petaflop is how supercomputing power is measured, one petaflop equating to one quadrillion floating point operations per second. Simply put, this new NVIDIA-powered data center will be very powerful.

The NVIDIA DGX A100. Image source: NVIDIA.

AI is about more than just computer science. The discipline is being applied across many fields of study. Life sciences are using data to study ecology, find cures for disease, and study climate change. AI is transforming diverse industries like energy, healthcare, financial services, and entertainment.

But just as in the past, technology has the potential to grow inequality. Part of UF's endeavor is to empower educators at K-12 schools and other higher education institutions with its AI system. As for UF specifically, data science will be integrated across the whole campus, and AI study implemented into the curriculum for all disciplines. There is a growing belief that to stay relevant in the AI and technology race, there needs to be more investment in education. UF therefore wants to become known as the first AI university.

Besides hardware, AI demands a massive amount of data to work with and a software framework that governs how the hardware operates. While UF (and a fast-growing list of other organizations around the globe) bring the data, NVIDIA brings its software for developers and a curriculum of training to the table. The sum of the parts puts NVIDIA at the forefront of a massive AI movement that could become a trillion dollar-a-year industry in the next decade.

UF's investment is comparatively small but has a potentially massive payoff in just a few short years.

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NVIDIA and University of Florida Release New AI Curriculum Spanning All Educational Disciplines - Motley Fool

Supercomputing Pipeline Aids DESI’s Quest to Create 3D Map of the Universe – HPCwire

Posted on July 21, 2020 by Danzig

July 21, 2020 As neuroscientists work to better understand the complex inner workings of the brain, a focus of their efforts lies in reimagining and reinventing one of their most basic research tools: the microscope. Likewise, as astrophysicists and cosmologists strive to gain new insights into the universe and its origins, they are eager to observe farther, faster, and with increasing detail via enhancements to their primary instrument: the telescope.

In each case, to unravel scientific mysteries that are either too big or too small to see with a physical instrument alone, they must work in conjunction with yet another critical piece of equipment: the computer. This means more data and increasingly complex datasets, which in turn impacts how quickly scientists can sift through these datasets to find the most relevant clues about where their research should go next.

Fortunately, being able to do this sort of data collection and processing in near real time is becoming a reality for projects like theDark Energy Spectroscopic Instrument(DESI), a multi-facility collaboration led by Lawrence Berkeley National Laboratory whose goal is to produce the largest 3D map of the universe ever created. Installed on the Mayall Telescope at Kitt Peak National Observatory near Tucson, Arizona, DESI is bringing high-speed automation, high-performance computing, and high-speed networking to its five-year galaxy-mapping mission, capturing light from 35 million galaxies and 2.4 million quasars and transmitting that data to the National Energy Research Scientific Computing Center (NERSC), a U.S. Department of Energy user facility based at Berkeley Lab that serves as DESIs primary computing center.

We turn the raw data into useful data, said Stephen Bailey, a physicist at Berkeley Lab who is the technical lead and manager of the DESI data systems. The raw data coming off the telescope isnt the map, so we have to take that data, calibrate it, process it, and turn it into a 3D map that the scientists within the broader collaboration (some 600 worldwide) use for their analyses.

Over the last several years the DESI team has been using NERSC to build catalogues of the most interesting observational targets, modeling the shapes and colors of more than 1.6 billion individual galaxies detected in 4.3 million images collected bythree large-scale sky surveys. The resultingDESI Legacy Imaging Surveys, hosted at NERSC, have performed their catalogue generation at NERSC over the course of eight data releases. The DESI project also leverages the Cosmology Data Repository hosted at NERSC, which contains about 900TB of data, and NERSCs Community File System, scratch, and HPSS storage systems.

The previous big survey was a few million objects, but now we are going up to 35-50 million objects, Bailey said. Its a big step forward in the size of the map and the science you can do with.

But storage is only part of the services NERSC delivers for DESI. The supercomputing center has also been instrumental in developing and supporting DESIs data processing pipeline, which facilitates the transfer of data from the surveys to the computing center and to users. The project uses 10 dedicated nodes on the Cori supercomputer, enabling the pipeline to run throughout each night during a survey and ensure that the results are available to users by morning for same-day analysis, often helping to inform the next nights observation plan. The DESI team also uses hundreds of nodes for other processing and expects to scale to thousands of nodes as the dataset increases. To facilitate data I/O, DESI depends on the NERSC data transfer nodes, which are managed as part of a collaborative effort between ESnet and NERSC to enable high performance data movement over the high-bandwidth 100Gb ESnet wide-area network.

DESI is using the full NERSC ecosystem: computing services, storage, the real-time queue, and real-time data transfer, Bailey said. Its a real game changer for being able to keep up with the data.

Optimizing Python for CPUs and GPUs

While gearing up for the five-year DESI survey, which is expected to begin in late 2020, NERSC worked with the DESI team to identify the most computationally intensive parts of the data processing pipeline and implement changes to speed them up. Through the NERSC Exascale Science Applications Program (NESAP), Laurie Stephey, then a postdoctoral researcher and now a data analytics engineer at NERSC, began examining the code.

The pipeline is written almost exclusively in Python a specialty of Stepheys which enables domain scientists to write readable and maintainable scientific code in a relatively short amount of time. Stepheys goal was to improve the pipelines performance while satisfying the DESI teams requirement that the software remain in Python. The challenge, she explained, was in staying true to the original code while finding new and efficient ways to speed its performance.

It was my job to keep their code readable and maintainable and to speed it up on the Cori supercomputers KNL manycore architecture, Stephey said. In the end, we increased their processing throughput 5 to 7 times, which was a big accomplishment bigger than Id expected. This means that something that previously took up to 48 hours now happens overnight, thus enabling analysis during the day and feedback to the following nights observations, Bailey noted. It also saves the DESI project tens of millions of compute hours at NERSC annually.

New experiments funded by DOE approach NERSC for support all the time, said Rollin Thomas who runs NESAP for Data. And experiments that already use NERSC are capitalizing on our diverse capabilities to do new and exciting things with data. DESIs sustained engagement with NERSC, through NESAP for Data, the Superfacility initiative and so on, is a model for other experiments. What we learn from these engagements helps us serve the broader experimental and observational data science community better.

And the optimization effort isnt over yet. The next challenge is to make the DESI code compatible with the GPUs in NERSCs Perlmutter system, which is slated to arrive in late 2020. Bailey and Stephey began this process last year Stephen was instrumental in rewriting the algorithm in a GPU-friendly way, Stephey noted but in April NERSC hired one of its newest NESAP postdocs, Daniel Margala, to take over. As a graduate student, Margala had previously worked with Bailey on the Baryon Oscillation Spectroscopic Survey, a DESI predecessor project, so Im familiar with a lot of the data processing that needs to be done for DESI, he said.

So far, Margalas focus is on preparing DESIs code for GPUs so that it will be ready to leverage the full potential of the Perlmutter system. He is currently working with a small subset of DESI data on Coris GPU testbed nodes; the long-term goal is to make sure the software is ready to handle DESIs entire five-year dataset.

The astrophysicists and scientists on DESI are pretty comfortable using Python, so we are trying to do all of this in Python so that they will be able to understand the code we are writing and learn from it, contribute back to it, and maintain it going forward, Margala said.

Over the next few years, NERSC resources will also be critical to another, larger goal of the DESI project: reprocessing and updating the data.

Every year we are going to reprocess our data from the very beginning using the latest version of all of our code, and those will become our data assemblies that will then flow into the science papers for the collaboration, Bailey said. We only need 10 nodes at NERSC to keep up with the data in real time through the night, but if you want to go back and process 2, 3, 5 years of data, thats where being able to use hundreds or thousands of nodes will allow us to quickly catch up on all that processing.

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Supercomputing Pipeline Aids DESI's Quest to Create 3D Map of the Universe - HPCwire

New Study Says the Moon’s Age is Millions of Years Off – NBC Palm Springs

Posted on July 21, 2020 by Danzig

The moon is a constant in our lives. It causes Earths ocean tides to ebb and flow, it stabilizes the planets axial tilt and, until recently, it was assumed to have accompanied the Earth for over 4.5 billion years.

A new study has posited that previous estimates of the moons age were millions of years off.

Scientists from theGerman Aerospace Centercalculated how long it took themoons magma ocean its a widely held belief that the lunar surface was once molten to cool, and they estimated that the moon is actually almost 100 million years younger than previously thought about 85 million years younger, to be exact.

So the moon, they say, was actually born at the tail-end of the Earths formation.

This is the first time that the age of the Moon can be directly linked to an event that occurred at the very end of the Earths formation, namely the formation of the core,saidThorsten Kleine, study co-author from the Institute of Planetology at the University of Mnster in Germany.

Their findings were published this month in the journalScience Advances.

Many scientists agree on the moons origin story: Around 4.51 billion years ago, the Earth was still heating up and changing rapidly. During that time, it collided with a protoplanet called Theia, which sent rock shooting off Earth and into space.

Theia gets it name from one of the titans in Greek mythology, known as the mother of the moon goddess Selene. Nothing remains of the protoplanet.

This debris eventually collected over a couple thousand years and formed Earths natural satellite the moon.

The energy that resulted from the agglomeration of rock created an ocean of magma on the nascent moons surface. It eventually crystallized and formed the lunar surface as we know it today.

Samples returned from the moon during the Apollo missions and Soviet Luna robototic missions have not helped to provide data for an exact age of the moon. So scientists have had to explore other methods.

Using a computer model, the team of scientists estimated how long it took the moons magma ocean to cool and solidify. Knowing how long that process of crystallization took clued them into how old the moon truly is.

Previous models estimated that it took up to 30 million years for the magma ocean to cool. This new study has suggested those models were millions of years off.

But how to re-create a process that took place during the very beginning of the solar systems existence? That part required a great deal of imagination and creativity, the researchers said.

The scientists also needed to calculate the composition of the ancient minerals that formed when the ocean solidified. This helped them link different types of rocks to certain stages of the magma oceans evolution.

All that modeling found that it took the moon nearly 200 million years to cool from its molten form and create what we now know as the lunar crust.

Scientists looked to the moons mineral composition to estimate that the moon is around 4.425 billion years old, or 85 million years younger than what previous studies had proven. Thats around the time Earths core settled, the researchers said.

The-CNN-Wire

New Study Says the Moon's Age is Millions of Years Off - NBC Palm Springs

The moon is about 85 million years younger than we thought, new study finds – KMOV.com

Posted on July 21, 2020 by Danzig

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The moon is about 85 million years younger than we thought, new study finds - KMOV.com

If we fly by Venus, well zoom to Mars faster (and cheaper) supposedly – SYFY WIRE

Posted on July 21, 2020 by Danzig

Future Mars missions have been hyped up all over the internet and beyond. Using the upcoming Lunar Gateway as a way station is one option, but what if there was a faster way that didnt involve the Moon (no offense to our satellite) or massive amounts of fuel?

Such a way does exist. Because waiting too long for planets to align is not an option, a team of scientists and engineers have proposed a way to use Venus as a cosmic slingshot to Mars. The spacecraft would use the same gravity assist method as the Voyagers and Cassini. It would take advantage of our sister planets gravity by approaching just close enough to marginally slow down the orbiting planet, whose energy would then shoot it to Mars, but not before astronauts on the mission got to study the mysterious second planet.

You know this method has to have some potential if NASA hinted at it in its Plan for Sustained Lunar Exploration and Development, which also included possibilities for Mars.

"'Humans to Mars Via Venus'is logical, exciting, and offers unprecedented science at Mars and Venus at a fraction of the cost of dedicated crewed missions to both, the scientists said in a white paper currently on the preprint server ArXiv. Venus is how we get to Mars.

It would also take less time. If we were to take the route of a conjunction mission, which relies on two planets orbits aligning, the launch would have to be put off for up to a year and a half. Getting to and from Mars would also take longer. That means 180 days each way and 550 days on the Red Planet. You really dont want to deal with living in deep space for too long when the human body isnt made to exist without gravity. An opposition mission, which is the type being suggested now, would put the spacecraft in a position to be launched toward Mars by the gravitational forces of Venus. This is how Voyager 2 managed its tour of all the planets before drifting off to the outer reaches of the solar system.

NASAs probe pulled off an opposition mission by borrowing some gravitational energy from Jupiter and Saturn, though most notably Jupiters. It approached until the gas giants gravity pulled it in, increasing its speed until its own gravitation pulled at Jupiter, marginally decreasing the orbiting planets momentum as it moves in an arc. This might have not been a big deal for something as gargantuan as Jupiter. For Voyager 2, it was huge. What the spacecraft took from Jupiter boosted the momentum it already had and gave it enough power to launch in the opposite direction, with the planets gravity bending its path toward Saturn, where it would repeat the process. Both Voyagers are now trekking through interstellar space.

Venus isnt just a convenient gas station for energy. While gravitational energy will save what would otherwise be a crushing amount of money spent on fuel (and liftoff when you factor in the extra weight), NASA is considering plans for astronauts to get a closer look at its toxic skies and scorching surface before they take off again. Contrary to what sci-fi would have you believe, robot brains are not infallible. Human brains are much better at making observations during a flyby. Rovers and other instruments can ride along with the astronauts and be controlled with a joystick in what sounds like the most awesome space video game ever.

Manned missions to Venus were part of our space agencys plans anyway. Why not just use an excursion to Mars as an opportunity?

A science-intensive flyby of Venus on any leg of a crewed mission to Mars makes any such endeavor a two-planet mission. Venus science is every bit as interesting and important as Mars, and just as crucial to comparative planetology, the scientists said. It is likely that a two-planet mission approach would more than justify adding a Venus science focus to Mars-bound flybys of Venus.

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If we fly by Venus, well zoom to Mars faster (and cheaper) supposedly - SYFY WIRE

Big Coffee Sellers Use Blockchain To Connect Farmers And Customers – Forbes

Posted on July 21, 2020 by Danzig

Folgers brand coffee to use the IBM blockchain platform connecting producers to customers.

Production transparency and blockchain technology are natural partners in the transformation of supply chain management.This may seem like a business platitude written about a new corporate event, but distributed ledger technology keeps making progress with large companies.

Farmer Connect announced today that it would partner with Smuckers Folgers brand coffee to use the IBM IBM blockchain platform connecting producers to customers.A QR code will allow consumers who buy 1850 Coffee to see how it was grown and brought to the shelf.

Farmer Connect wants to eliminate inefficiencies in our food supply this means removing the middleman and third-party services, which take from the small farmers bottom line.Blockchain technology will validate the food crop, in this case coffee, to the farmer and its source location.

Will this increase coffee sales?The future is unclear; no one knows today.

Blockchain authentication and identification may not grow Smuckers profits, but it could help farmers better manage their crops directly with broader markets.In effect, this announcement between Farmer Connect, IBM and Smucker is a prototype for new blockchain ventures.

Folgers will be the first large U.S. food brand to use this service.IBM said in the announcement, Leveraging IBMs blockchain technology, consumers can now trace their coffee back to its origin on a platform designed to help increase traceability, efficiency and fairness in the coffee supply chain.

Farmer Connects website will provide where the coffee was grown, processed, and exported.Consumers can understand if the drink in their hands was part of clean water and small farm agriculture initiatives.

We know that consumers are increasingly interested in transparency in the supply chains for the products they enjoy and we have been committed to helping promote this as part of our coffee sustainability strategy, said Joe Stanziano, senior vice president and general manager of coffee at the J.M. Smucker Company. Our work with Farmer Connect and IBM not only helps connect coffee lovers to the producers who provide their favorite morning drink, it also gives them the opportunity to support these hardworking smallholder farmers and their families.

Time will tell.

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Big Coffee Sellers Use Blockchain To Connect Farmers And Customers - Forbes

What is the strategic business value of blockchain in finance and beyond? – Information Age

Posted on July 21, 2020 by Danzig

The technology behind Bitcoin and other cryptocurrencies has a growing use of applications for a number of industries. Here, four experts explore the strategic business value of blockchain in finance and beyond

As blockchain enters the mainstream, what value does the technology bring?

The strategic business value of blockchain is growing.

Initially, blockchain technology powered the infamous cryptocurrency boom, giving rise to Bitcoin, Ethereum and much more.But, now the applications for blockchain technology are growing in a number of industries.

Its presence is felt more than any other in mainstream finance, where it has gained huge momentum.

Once a niche for crypto-experts and coding buffs, now big traditional institutions and even central banks are looking to blockchain as they build the foundations for the next generation of financial services, explainsDmitry Tokarev, CEO and founder, Copper Technologies.

Below, taking into account the impact of the current pandemic on the healthcare and financial systems, Tokarev and three otherexperts explore the strategic business value of blockchain in finance and beyond.

Tokarev believes that in the investment space, the rise of Covid-19 and the resulting economic turmoil has led institutional investors, from traditional hedge funds to major banks, to begin looking at cryptoassets as a hedge against the market and impending inflation.

He says: 10 years ago, a bank like JP Morgan would have been extremely sceptical of cryptocurrencies now they offer a crypto bank account.

Meanwhile in the policy space, Tokarev explains there are major steps being taken towards the adoption of blockchain technology. In the UK, the Bank of England is actively exploring how they would implement a Central Bank Digital Currency (CBDC), while some countries, like Lithuania, are already issuing crypto coins in early trials.

Blockchain is already being widely accepted and adopted, shaping the future of finance. The question now is how firms will integrate this step-change infrastructure without losing the edge of innovation or competitive advantage.

As use cases for the technology grows, every business and CTO, or equivalent, will need a blockchain guide to help them navigate unfamiliar territory. Read here

Perhaps more than any other market, the financial services industry is experiencing rapid disruption with the entrance of new players, such as neo banks and Fintechs.

To cope with the evolving needs of customers, companies mustadopt new technologies to outpace their competitors and remain relevant.

According to Marcus Treacher, SVP customer success at Ripple, the key battleground in the payments industry today lies in improving antiquated cross-border transfers.

Traditional payments processes are slow, costly and unreliable. Blockchain technology has the potential to revolutionise the current broken model by enabling faster, more transparent and cost-effective cross-border payments that can be processed in seconds, not days or weeks.

Findings from Ripples recent Blockchain Payments Report showed that 45% of respondents are already in production, piloting or close to signing with a blockchain provider.

Treacher adds: If companies move fast and adopt blockchain, they can innovate quickly, meet customer demands and enjoy a significant return on their investment.

Blockchain use cases have to be identified before the technology can be adopted. Five experts do exactly that across their respective industries. Read here

Explaining the merits of the technology,Julian Sawyer, managing director, Europe, at Gemini, says that blockchain providesa fundamentally new, more efficient, secure and immutable way to transfer value and record transactions, unaffected by borders or physical locations. These characteristics mean there are huge opportunitiesfor blockchain to revolutionise processes and systems in industries that are not currently optimised.

On implementing blockchain technology, he continues: On any wide scale and realising its strategic value whether in a consumer or business setting will depend on how effectively these specific use cases and applications are developed.

The core advantages of blockchain lie in its decentralisation, cryptographic security and immutability.

Tamara Haasen, chief of staff at IOHK, reveals that the technology allows information to be verified by the network itself and for value to be exchanged without having to rely on a third-party intermediary. Rather than there being a singular form of blockchain, the technology can be configured in multiple ways to meet the objectives and commercial requirements of particular use cases.

This means that blockchain has the disruptive potential to empower new operating models, but its initial impact will be to drive operational efficiencies and security, harnessing the power of multiple verifying computers, in multiple locations, ensuring no single point of failure, or focus for a targeted attack.Cost can be taken out of existing processes by removing intermediaries, or the administrative effort of record keeping and transaction reconciliation. This can shift the flow of value by capturing lost revenues and creating new revenues for blockchain-service providers, continues Haasen.

As an example, she points to the recent Cardano Virtual Summit 2020, where Atala PRISM was launched.

This is a decentralised identity system, compatible with any blockchain system and with the potential to give millions of unbanked people self-sovereign identities and access to a blockchain marketplace of financial and social services. The potential for blockchain to become a new open-standard protocol for trusted records, identity and transactions, is therefore very much here to stay, she adds.

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What is the strategic business value of blockchain in finance and beyond? - Information Age

Chronicled and Deloitte Ally to Accelerate Blockchain in the Life Sciences – AiThority

Posted on July 21, 2020 by Danzig

Chronicled and Deloitte announced an alliance to bring blockchain-powered solutions to the life sciences and health care industry. The alliance will leverage technology and solutions powered by Chronicleds MediLedger Network, a blockchain-enabled network for the life sciences industry, to bring interoperability, security and efficiency to processes between companies in revenue management and the pharmaceutical supply chain.

Part of the new alliance between Chronicled and Deloitte includes a solution to help fight counterfeits and fraud in the medication used for the treatment of COVID-19, an issue that has increased dramatically since the start of the pandemic. MediLedgers product verification solution can enable pharmacies and hospitals to authenticate high risk or suspect products. It works through a barcode scan that validates product data against the original manufacturers data. MediLedger already enables verification by pharmaceutical wholesalers for more than 95% of drugs being re-sold in the US and is among the first blockchain-based solutions deployed in commercial use around the world.

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Chronicled has the potential to radically reshape the way product is tracked and managed within the health care ecosystem, saidDavid Carlson, managing director, Deloitte Consulting LLP, and leader for the Chronicled relationship. As the life sciences industry moves quickly to get innovative therapies to market during this critical time, stakeholders are looking for solutions that enhance pricing transparency while creating an efficient mechanism to exchange product use and financial information. Chronicled is an important player in the effort to better collaborate across the value chain and Deloitte is well positioned to drive large scale industry transformation.

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In addition to product verification on MediLedger, Chronicled will launch a second solution this summer called Contracts & Chargebacks aimed at eliminating disputes, improving cash flow and identifying revenue leakage in the chargeback process between manufacturers, distributors and group purchasing organizations. MediLedger can enable significant improvements to these processes, helping companies transact and share data with each other and avoid delays, inaccuracies, poor customer service and lost revenue.

Chronicled is pleased to be working with Deloitte to offer the MediLedger Network to the health care industry, most importantly to do our part in the fight against COVID-19, saidSusanne Somerville, CEO of Chronicled. CombiningChronicleds innovative product verificationand contracts and chargebacks solutions and Deloittes deep experience with implementation and the complexities of these business processes, we have the ability to create tremendous value for the industry and the world.

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Chronicled and Deloitte Ally to Accelerate Blockchain in the Life Sciences - AiThority

Blockchain Could Help to Boost Global Jobs Creation – Cointelegraph

Posted on July 21, 2020 by Danzig

A report published by the World Economic Forum, or WEF, highlighted the critical role of fourth industrial revolution technologies. New technologies like blockchain could help stimulate growth by implementing nature-positive solutions following the COVID-19 outbreak.

According to the Future of Nature and Business study shared with Cointelegraph, nature-friendly solutions could have the capacity to create 395 million jobs and generate $10.1 trillion in business opportunities by 2030.

Inger Andersen, United Nations Under-Secretary-General and Executive Director of the UN Environment Program, commented on the matter:

As we enter into a historic decade of action to halt and reverse biodiversity loss by 2030 and address climate change, business has a critical role to play in environmental stewardship of our planet. They have the technology, innovation and financing to make the shifts we need towards increased investment in natures infrastructure and nature-based solutions.

Blockchain technology could contribute to a $365 billion savings by reducing food waste in the food supply chain.

Pilot programs were launched in Benin, Ghana, India, and Rwanda. Their results suggest that relatively low-cost storage techniques and handling practices can reduce post-harvest food loss by more than 60%. They can also raise smallholders incomes by more than 30%, the report claims.

One example that the WEF puts forth in the study is the IBM Food Trust. This project has already started to implement blockchain-based supply chains with partners like Walmart, Tyson Foods, Nestle, and others.

The report further elaborates that blockchain applications in energy and mining supply chains could generate an opportunity worth $30 billion in 2030:

Blockchain applications could grow rapidly over the coming decade, particularly in precious gems, diamonds, tin, tungsten and cobalt (...) Economies of scale will enable companies to unlock significant cost savings from initial blockchain investments, eliminating the need for costly materials verification processes.

The report notes that innovations such as additive manufacturing, precision forestry, and blockchain in energy and mining supply chains can enable a nature-positive pathway by supporting both value creation and conservation goals.

The WEF called to scale blockchains potential to help create $3.5 trillion of value in energy and extractive systems.

Excerpt from:

Blockchain Could Help to Boost Global Jobs Creation - Cointelegraph

Blockchain in Education Market Research Analysis Including Growth Factors, Types And Application By Regions From 2020 To 2027 – Cole of Duty

Posted on July 21, 2020 by Danzig

The New Report Titled as Blockchain in Education Market published by Reportspedia, covers the market landscape and its evolution predictions during the forecast period. The report objectives to provide an overview of global Blockchain in Education Market with detailed market segmentation by solution, security type, application and geography. The Blockchain in Education Market is anticipated to eyewitness high growth during the forecast period. The report delivers key statistics on the market status of the leading market players and deals key trends and opportunities in the market.

Request For Free Sample Report: @ https://www.reportspedia.com/report/business-services/2015-2027-global-blockchain-in-education-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/58050#request_sample

This research report also includes profiles of major companies operating in the global market. Some of the prominent players operating in the Global Blockchain in Education Market are:

odem.ioOracleDISCIPLINAIBMLiveEduRecordsKeeperOpen Source UniversityBlockcertsGilgameshLearning Machine

The Blockchain in Education Market for the regions covers North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Regional breakdown has been done based on the current and forthcoming trends in the global Blockchain in Education Market along with the discrete application segment across all the projecting region.

Ask For Discount: https://www.reportspedia.com/discount_inquiry/discount/58050

The Type Coverage in the Market are:

Credentials VerificationExpanding MOOCsDigital Rights ProtectionOpen Source UniversitiesSchool Assets Tracking & ManagementOthers

Market Segment by Applications, covers:

UniversityPersonnel RecruitmentsDigital Rights ManagementOthers

Some Major TOC Points:

Chapter 1. Blockchain in Education Market Report Overview

Chapter 2. Global Blockchain in Education Market Growth Trends

Chapter 3. Market Share by Key Players

Chapter 4. Blockchain in Education Market Breakdown Data by Type and Application

Chapter 5. Market by End Users/Application

Chapter 6. COVID-19 Outbreak: Blockchain in Education Industry Impact

Chapter 7. Opportunity Analysis in Covid-19 Crisis

Chapter 9. Market Driving Force

Continue for TOC

Do you want any other requirement or customize the report, Do Inquiry Here: https://www.reportspedia.com/report/business-services/2015-2027-global-blockchain-in-education-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/58050#inquiry_before_buying

Key questions Answered in this Blockchain in Education Market Report:

What will be the Blockchain in Education Market growth rate and value in 2020?

What are the key market predictions?

What is the major factors of driving this sector?

What are the situations to market growth?

Major factors covered in the report:

Global Blockchain in Education Market summary

Economic Impact on the Industry

Blockchain in Education Market Competition in terms of Manufacturers

Blockchain in Education Market Analysis by Application

Marketing Strategy comprehension, Distributors and Traders

Study on Market Research Factors

Table of Content & Report Detail @ https://www.reportspedia.com/report/business-services/2015-2027-global-blockchain-in-education-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/58050#table_of_contents

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Blockchain in Education Market Research Analysis Including Growth Factors, Types And Application By Regions From 2020 To 2027 - Cole of Duty

OKEx Wraps Up Its Beacon Program Furthering Education in the Blockchain Space – PRNewswire

Posted on July 21, 2020 by Danzig

VALLETTA, Malta, July 20, 2020 /PRNewswire/ --OKEx(www.okex.com), a world-leading cryptocurrency spot and derivatives exchange, has finished its Beacon Program- European Edition, which provided three masterclasses by prominent players in the cryptocurrency space and individual mentoring from top OKEx executives, including CEOJay Haoand Director of Financial MarketsLennix Lai.

Made up of a total of six participants with varying degrees of experience in cryptocurrency, the Beacon Program aimed to further education in the blockchain space and provide European participants- particularly hard-hit by the coronavirus pandemic- with the opportunity to explore crypto and blockchain in greater depth and even consider a new career path.

The first class of the series was given by Crypto 101's Matthew Aaron and Dani Ansalem, which offered a basic introduction to cryptocurrency, what to look at when investing in it, how to buy and store it, and other important factors to keep in mind. The second class by CNBC Crypto Trader's Lindsay Joo covered the ICO mania, with a particular focus on South Korea and on encouraging participants to examine the real utility of blockchain in a project at the time of investing.

The final masterclass was given by OKEx's very own Lennix Lai and took participants a little deeper into cryptocurrency, exploring the issue of tokenomics and why tokens make a far better form of equity than shares.

The feedback from participants was extremely encouraging, with one student, Phillip Taffley, commenting, "I found the Beacon Program very beneficial, and I am very grateful for being given the opportunity to be part of it." Beyond the masterclasses and daily news briefings, the program also provided mentorship, which Taffley received from Lennix. Taffley said, "As a newbie to the industry this aspect of the course was of particular interest. It helped me gain a good foundation upon which I built a wider understanding by conducting my own research."

One of Jay's mentees, Dmytro Sokoliuk, told OKEx,"Mr. Jay Hao gave me individual advice and said, 'You can think about what you're good at and interested in. For the topics of writings videos, etc., it's always good to focus on what's new in the crypto industry and give your own insights toward it.' Thanks to his words, I know that I'm moving in the right direction. [] I want to say an individual 'thank you' for each of the lectors and for having Jay Hao as a mentor."

For their part, the Beacon Program teachers also found the experience enriching. Lindsay Joo told OKEx that she was honored to be included in the program, saying that giving her class was both fun and rewarding, while Matthew Aaron was extremely upbeat, saying that he found the experience very enjoyable. "I love this stuff!" he enthused.

Jay concluded by saying,"We're extremely pleased with this first initiative of the Beacon Program masterclasses and mentorship. Overall, we found it a valuable experience and are encouraged by the feedback from the participants. Their comments are positive and have also highlighted ways we can improve the program in the future if we run a second edition."

Lennix added,"It was a privilege to share my knowledge with such motivated and ambitious participants. I would also like to say thank you to Lindsay and Matthew for giving their time and helping us make this a success."

About OKEx

A world-leading cryptocurrency spot and derivatives exchange, OKEx offers the most diverse marketplace where global crypto traders, miners and institutional investors come to manage crypto assets, enhance investment opportunities and hedge risks. We provide spot and derivatives trading- including futures, perpetual swap and options- of major cryptocurrencies, offering investors flexibility in formulating their strategies to maximize gains and mitigate risks.

SOURCE OKEx

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OKEx Wraps Up Its Beacon Program Furthering Education in the Blockchain Space - PRNewswire

Lets turn the tide this November – The Ellsworth American

Posted on July 21, 2020 by Danzig

By Roger Bowen

the White House will be adorned by a downright moron

H.L. Mencken

My partner of 50-plus years and I live at one of the most remote spots on Americas East Coast, also one of the most beautiful. Our small fishing village gives genuine meaning to the heavenly words peace and quiet. We do hear the occasional gunshot during the fall deer hunting season and fireworks on July Fourth, but these noxious interruptions to our psychic balance mercifully pass. When the noises end the bald eagles, sharp-shinned hawks, snowshoe hares, foxes, bobcats, chickadees and chipmunks come out of hiding and life as we love it returns in all its fullness.

COVID-19 thus far has been tolerable. Only 18 souls in our county have been infected; just one has died. Nevertheless, most residents and visitors wear masks whenever they travel to the nearby shire town, they practice social distancing, they wash their hands after every visit to the local post office or grocery store, and they avoid crowds. Our neighbors prudence and regard for community welfare reassures us that we live exactly where we should.

More worrying to us are the health and safety of our two children and two grandchildren. One child lives just north of Boston, the other, and mother of our grandies, lives on Long Island while her husband works in Manhattan. They all hope to visit us at the end of this month. It is an annual ritual that enriches the spirits of us all. Several years ago, when our grandson was just 5 years old and his baby sister only 2, he placed his kiddy rocker on the deck looking out onto the Atlantic, and quietly uttered, You know, Maine is the only place where I can really relax.

What frightens me more than the virus is our President and his most ardent supporters. Trump is a philosophical nihilist who has no firm convictions about anything other than his own glorification. His nihilism has been embraced by his diehard base. They are the ones who defiantly proclaim that they can defy government mandates to wear a mask because they are free, even as they fasten their seat belts, pay taxes, send their children to school and obey the laws of civil society.

To date, Trump has told them what they want to hear: wearing or not wearing a mask is a personal choice made by freedom-loving individuals; CDC guidelines are voluntary; malarial medication and Lysol kill the virus and somehow the virus will magically disappear on its own accord. Thats leadership.

They believe Trump when he describes the Black Lives Matter movement as manipulated by radical leftist fascists; they believed Trump when he said some of the racists in Charlottesville are good people. They believe Trump when he tells them that his tax reform benefits every American; Wall Street just smiled. They believe him when he denies he is Putins puppet, when he denies being briefed about Russia paying the Taliban a bounty for killing American soldiers, when he promises to make America great again, etc. Trump has told over 18,000 lies since assuming office and his base seems to have swallowed most of them. One of the great elitist cynics of the 20th century, H L Mencken, once wrote: No one in this world has ever lost money by underestimating the intelligence of the great masses of plain people.

Americas Bill of Rights was written to protect Americans from government overreach and to enshrine the rights of the individual. Now as never before, at least in my lifetime, have the First Amendment guarantees of freedom of speech, freedom of the press, the right to peaceably assemble and to redress grievances meant more. Of course, rights are meaningless unless you exercise them.

Now is the time to prove Mencken was mistaken. Do not be taken in by Trumps lies, listen to the CDC experts and vote this November to remove Trump from office. Our democracy is at stake. And I want our grandchildren to grow up unencumbered by fears, of COVID and of the egotist occupying the White House.

Roger Bowen held nonpartisan elective offices in Gouldsboro for 10 years. He currently works (remotely) for a Washington, D.C., higher education nonprofit.

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Lets turn the tide this November - The Ellsworth American

Rahan Meristem (1998) LTD and its Partner Banarica Report Success in Mitigating Panama Disease After Field Trials in the Philippines – Business Wire

Posted on July 21, 2020 by Danzig

ROSH HANIKRA, Israel--(BUSINESS WIRE)--Rahan Meristem, with the aid of our Colombian partner Mr. Luis Alberto Restrepo President of Banarica Colombia, developed Cavendish banana plants with apparent resistance to Panama disease TR4, reports the Scientific Director Dr. Eli Khayat. The data were recently published and received tremendous public and scientific attention. The technology, does not entail genetic engineering. These data corroborate the Companys earlier findings that its proprietary In-vitro mutagenesis technology is effective for creating novel traits. In addition to these disease-resistance data, Rahan has previously shown both an increase in banana fruit production and improvement in plant architecture.

The data lead to the achievement of Rahan's R&D objective developing a "Cavendish" banana with resistance to fungal diseases.

TR4 strain of Panama disease is the primary constrain in the banana industry, stated Mr. Ron Diner, CEO of Rahan: The fact that our technology can benefit the banana industry in a variety of ways is our major strategic goal. We are working with our partners to salvage the Cavendish banana.

About Rahan Meristem

Rahan Meristem is considered one of the most outstanding companies for plant breeding and propagation. We use cutting edge molecular biology breeding techniques, and developed tissue culture protocols for over 200 plant genera. Rahans labs are among the most advanced in the world. Rahan operates 4 laboratories worldwide, in Israel, Colombia, Ecuador and the Philippines. The R&D department specializes in breeding crops by in vitro mutagenesis and genome editing.

Certain statements included in this press release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Actual results could differ materially from such statements expressed or implied herein as a result of a variety of factors, including, but not limited to: the development of the Companys gene technology; the approval of the Companys patent applications; the successful implementation of the Companys research and development programs and joint ventures; the success of the Company's license agreements; the successful conversion of the Companys letter of intent into a license agreement; the acceptance by the market of the Companys products; competition and the timing of projects and trends in future operating performance, as well as other factors expressed from time to time in the Companys periodic filings with the Securities and Exchange Commission (the "SEC"). As a result, this press release should be read in conjunction with the Companys periodic filings with the SEC. The forward-looking statements contained herein are made only as of the date of this press release, and the Company undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.

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Rahan Meristem (1998) LTD and its Partner Banarica Report Success in Mitigating Panama Disease After Field Trials in the Philippines - Business Wire

Ultrasound Imaging Extended Into the Microscopic Realm – Technology Networks

Posted on July 21, 2020 by Danzig

Ultrasound imaging, as most people are familiar with it, is used for taking pictures of a fetus while it is still inside the womb, but it has other medical purposes, such as diagnosing diseases of organs and tissues.

For years, Caltech's Mikhail Shapiro has been working to extend ultrasound imaging into the microscopic realm as well. Now, through a new breakthrough based on genetic engineering, he is making it possible for researchers to use ultrasound to watch enzymes at work within cells.

In a new paper appearing in the journal Nature Chemical Biology, Shapiro and lead authors Anupama Lakshmanan (PhD '19) and medical engineering graduate student Zhiyang Jin, and their fellow researchers, describe how they have harnessed the genes for a protein that helps bacteria float in water to create a microscopic ultrasound marker that indicates when certain enzymes are active inside cells.

This advance builds upon previous research Shapiro's lab conducted on so-called acoustic reporter genes, which encode proteins that can be seen from outside the cell with ultrasound. The researchers borrowed these proteins from a species of buoyant bacteria. In those bacteria, the proteins form tiny air-filled protein shells, known as gas vesicles, that help the bacteria float in water. Shapiro's team discovered that gas vesicles show up strongly in ultrasound imaging, including when the genes encoding them are incorporated into other bacteria or mammalian cells.

Gas vesicles are the ultrasound equivalents of the popular green fluorescent protein, which, true to its name, is a protein that glows bright green. Researchers commonly use the gene for green fluorescent protein as a so-called reporter gene. If a cell is glowing green as viewed with optical microscopy, the gene is active. The main drawback of fluorescent reporter genes is that their products cannot be seen deep inside tissues like muscle that are not transparentas would be the case with most of the human body. In contrast, acoustic reporter genes are visible to ultrasound, which can penetrate deep into living tissue.

The patterns of expression of reporter genes are useful for monitoring the internal behavior of cells. For example, to learn more about how cells become neurons, a researcher could insert the reporter gene alongside a neuronal gene into an embryo's DNA. When the embryo's cells turn on the neuron gene, they will also express the reporter gene, and the cells will show a characteristic signature. This allows the researcher to easily see that the genetic program that encodes neuron formation is active.

This is only the first step though, Shapiro says.

"Gene expression is just one of the hundreds of important biological processes happening inside the cell," he says. "So, watching that is great, but we want to extend our view to all other activities in the cell."

This extension has already been made with fluorescent proteins, variants of which have been designed to change their fluorescence in response to intracellular molecules such as calcium, lipids, or enzymes. These fluorescent "biosensors" are popular with researchers studying cellular biology under a microscope. But, as with other fluorescent proteins, they are hard to see in living tissues.

In their latest research, Shapiro's team developed the first biosensors for use with ultrasound, which allow researchers to tell when a specific enzyme has been busy at work within a cell located deep inside the body.

Enzymes are specialized proteins that act as biological catalyststhat is, they facilitate chemical reactions within a cell, creating new biological compounds and breaking down others, and they are involved in nearly every aspect of what a cell does in the course of its life. Because of the central role enzymes play in living things, researchers have been keen to understand how they behave inside cells.

Lakshmanan and Jin built upon what was learned in the prior gas-vesicle research and modified the gas vesicles, so they could be targeted by enzymes used by the cell.

They changed the proteins that form gas vesicles so that they could be recognized similarly to the natural targets of a few common and well-studied enzymes, which would thus cut the surface proteins to pieces.

"These surface proteins, we discovered, sit on the surface of the gas-vesicle shell and make it more rigid and influence its mechanical and acoustic properties," says Lakshmanan. "If you cut up the surface proteins, the shell becomes softer, so the gas vesicles are able to deform more easily." As a result, there is a brighter ultrasound signal when enzyme activity is increased. For her work with gas vesicles, Lakshmanan was awarded Caltech's 2019 Milton and Francis Clauser Doctoral Prize, which is given annually at commencement to the PhD candidate whose research is judged to exhibit the greatest degree of originality and potential for opening up new avenues of human thought and endeavor.

"These enzymes are the workhorses of the cell, and now we are watching the workhorses working," says Jin. "The beauty of our biosensor design is that it can be modified for whichever enzyme someone has an interest in studying. This is a platform for further research."

ReferenceLakshmanan, A., Jin, Z., Nety, S.P. et al. Acoustic biosensors for ultrasound imaging of enzyme activity. Nat Chem Biol (2020). https://doi.org/10.1038/s41589-020-0591-0

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.

Scientists find the secret ingredient to keep brain healthy; exercise in a pill may soon be a reality – Economic Times

Posted on July 21, 2020 by Danzig

By Gretchen ReynoldsExercise may help change exercisers brains in surprising ways, according to a new study of physical activity and brain health. The study, which included both mice and people, found that exercise prompts the liver to pump out a little-known protein, and that chemically upping the levels of that protein in out-of-shape, elderly animals rejuvenates their brains and memories. The findings raise provocative questions about whether the brain benefits of exercise might someday be available in a capsule or syringe form essentially exercise in a pill.

We already have considerable evidence, of course, that physical activity protects brains and minds from some of the declines that otherwise accompany aging. In past rodent studies, animals that ran on wheels or treadmills produced more new neurons and learned and remembered better than sedentary mice or rats. Similarly, older people who took up walking for the sake of science added tissue volume in portions of their brains associated with memory. Even among younger people, those who were more fit than their peers tended to perform better on cognitive tests.

But many questions remain unanswered about how, at a cellular level, exercise remodels the brain and alters its function. Most researchers suspect that the process involves the release of a cascade of substances inside the brain and elsewhere in the body during and after exercise. These substances interact and ignite other biochemical reactions that ultimately change how the brain looks and works. But what the substances are, where they originate and how they meet and mingle has remained unclear.

So, for the new study, which was published this month in Science, researchers at the University of California, San Francisco, decided to look inside the minds and bloodstreams of mice. In past research from the same lab, the scientists had infused blood from young mice into older ones and seen improvements in the aging animals thinking. It was like transferring a memory of youth through blood, says Saul Villeda, a professor at UCSF, who conducted the study with his colleagues Alana Horowitz, Xuelai Fan and others.

Those benefits were a result of the donor animals young age, though, not their exercise habits. The scientists suspected that exercise would spark additional changes in the bloodstream that might be transferable, whatever an animals years.

Intrigued, the scientists next set out to find what differed in the exercisers blood. Using sophisticated mass spectrometry and other techniques, they separated out and enumerated various proteins in the running animals blood that were not seen in similar profusion in blood from inactive mice.

Exercise may help change exercisers brains in surprising ways.

So, the researchers now employed genetic engineering to amplify the release of GPLD1 from the livers of old, inactive mice. Afterward, those animals performed almost like young mice on tests of learning and memory, and their brains teemed with far more newborn neurons than in other old mice. In effect, they gained the brain benefits of exercise without the effort of actually exercising.

To ensure that this reaction was not purely rodent-based, the scientists also checked blood drawn from elderly people. The older men and women who habitually walked for exercise showed higher levels of GPLD1 in their bloodstreams than those who did not.

The combined upshot of these findings seems to be that exercise improves brain health in part by prompting the liver to pump out extra amounts of GPLD1, Villeda says, although it is not yet clear how the protein then changes the brain. Subsequent experiments by the scientists showed that the protein probably does not breach the blood-brain barrier and act directly on the brain, Villeda says. Instead, it is likely to incite alterations in other tissues and cells elsewhere in the body. These tissues, in turn, produce yet more proteins that have effects on other tissues that eventually lead to direct changes to the neurotransmitters, genes and cells in the brain itself that undergird cognitive improvements.

Villeda believes that if further experiments show that GPLD1, in isolation, helps to initiate this molecular chain reaction, then it is at least conceivable that infusions of the substance might offer the brain benefits of exercise to people who are too frail or disabled for regular physical activity.

This experiment principally involved mice, though, not people, and does not tell us anything about the systemic effects of extra GPLD1, which in high amounts might be undesirable. More fundamentally, the findings highlight the pervasive, intricate, whole-body effects of exercise, with the liver, in this case, somehow changing minds and brains after workouts. At the moment, it is impossible to know if the same synchronized, interwoven processes all would occur in response to a GPLD1 exercise pill and, if not, whether it could be considered an exercise pill at all.

Villeda is quick to agree that pharmaceutical GPLD1, even if effective for brain health, would not recapitulate the benefits of exercise. There would be none of the usual fat burning, muscle building or cardiovascular improvements, he points out. But he hopes that, if future experiments in his lab with animals and people show consistent results, the substance might eventually help people who find moving difficult to think better.

Managing Parkinsons DiseaseBeing diagnosed with any health problem is taxing, but correctly understanding it is the key to dealing with a progressive, neurological condition. One such neurological condition is Parkinsons disease, first described by James Parkinsons 200 years ago. It is characterised by tremours, overall slowing, rigidity, falls, speech troubles, constipation and more.With research ongoing to find a permanent cure, there are many things one can routinely do to keep its multifaceted symptoms under control.On World Parkinsons Day, Dr Azad M Irani, Consultant Department of Neurology at Jaslok Hospital and Research Centre, shares some points that will help you fight the disease.

Educating Oneself About Their IllnessUnderstanding the disease is a key to successful management. Once diagnosed with Parkinsons, request your doctor for reliable sources of information. Avoid reading unreliable information online as it may often be untrue and stressful. Advice received during small talks with relatives and friends must also be counter-checked as it may often be untrue and add to unnecessary stress.

Treatment Compliance And Timely Follow-UpsOne must take medicines on time. Dont miss follow-up appointments. Dont adjust your own medication. These can be harmful.

Physical ActivityAn essential part of successful treatment is daily exercise and physiotherapy, as this can delay progression of symptoms significantly if done regularly. Adequate sleep, preventing constipation are very important to minimise symptoms. The significance of weight loss for those overweight-obese should be emphasised. Continuing household chores, taking walks, and yoga help delay progression of symptoms significantly.

Healthy LifestyleKeeping oneself fit with a nutritious diet, sleeping on time, and daily meditation to relax calm a worried mind.

Scientists find the secret ingredient to keep brain healthy; exercise in a pill may soon be a reality - Economic Times

Composite Thermoelectric Generator Material Easily Flexes and Stretches – Machine Design

Posted on July 21, 2020 by Danzig

This article appeared in Electronic Design and has been published here with permission.

Unless youre involved in cellular-biology research, you may not know about electroporation, which is a powerful yet basic method for delivering small molecules (RNA, DNA, drugs) across cell membranes by application of an electrical field. Its used in situations such as genetic engineering of cells related to drug- and DNA-based vaccine delivery, whereby a tool called an electroporator applies a jolt of electricity to temporarily open cell walls.

(Technical aside for non-biology-lab audience: One of the roles of a cell membrane is to serve as a protective border, isolating the inner workings of a living cell from the outside environment. But with a brief jolt of electricityelectroporationthat membrane will temporarily open and allow foreign molecules to flow in. This process has been used for decades in molecular biology labs for tasks ranging from bacterial detection to genetic engineering.)

Quality test equipment and tools can be expensive, even for relatively simple ones such as electroporators, which deliver a controlled, high-voltage spark and can cost hundreds or even thousands of dollars. To enable smaller labs and schools to do experiments, a team at Georgia Institute of Technology (better known as Georgia Tech) developed a simple, inexpensive, handheld electroporator dubbed the ElectroPen, inspired by and derived from a common household piezoelectric stove/barbecue lighter (Fig. 1).

1. Shown is a common butane lighter (left) from which researchers obtained a piezoelectric component used in the ElectroPen (right)an inexpensive electroporator that has a 3D-printed case. (Source: Georgia Tech)

Unlike commercial units that require batteries or an ac power source, this electroporator is self-powered by a piezoelectric crystal, thus reducing cost and complexity. It delivers repeatable exponentially decaying pulses of about 2,000 V in 5 ms.

This electroporator wasnt a one-time hack where the objective was simply to successfully repurpose the lighter to another role and then conclude good enough, now were done. Instead their project encompassed upfront material analysis including measurement of various piezoelectric crystals, performance tests like assessing consistency of applied force and resultant voltage output, and even issues of manufacturability at the Georgia Tech location and independent sites (Fig. 2). In addition to electrical and mechanical evaluations at the bench, they also used their device successfully for its intended electroporation experiments.

2. ElectroPen platform: (a) Design of the 3D-printed low-cost electroporation device along with a depiction of its size scale, demonstrating portability. The device is operated simply by pressing down the toggle to trigger the piezoelectric mechanism, resulting in electrical discharge. (b) Design of the alternative electroporation millifluidic channel. The millifluidic-channel design consists of two blocks (shown here in acrylic) covered with aluminum tape to act as electrodes and placed on a base with a gap distance of 0.1 cm. The millifluidic channel can be built out of other materials as an alternative for industrial equivalents. (c) Depiction of the origin of the piezoelectric ignition mechanism found within the common stove lighter. The inset is the striker/piezoelectric mechanism of the lighter. The region with the red cap consists of a metal housing encasing the piezoelectric crystal. The middle black region consists of the spring-latch mechanism that strikes the crystal. The bottom black region (rightmost) consists of a wedge thats the origin for user-applied force and triggers the spring mechanism. The toggle on a lighter directly exerts a force on this mechanism to produce a spark. (d) Illustration of the general protocol for using the ElectroPen system. The cellular suspension is added to the gap in the millifluidic channel, after which the ElectroPen is connected and pressed to trigger a voltage potential. The cell suspension is then recovered in Luria Bertani broth (a commonly used nutritionally rich medium for culturing bacteria) and plated. (e) Illustration of the individual components of the 3D-printed ElectroPen platform and custom millifluidic channel. (Source: Georgia Tech)

For example, the team tested several different lighter crystals to find ones that produced a consistent voltage using a spring-based mechanism with a 1000-frame/s camera to study the device mechanics in slow motion (Fig. 3). The final bill of materials (BOM) included copper-plated wire, heat-shrink wire insulation, and aluminum tape. To hold it all together, the researchers designed a 3D-printed casing that also serves as its activator. With all of the parts on hand, the device can be assembled in 15 minutes.

3. Spring-latch mechanisms for repeatable generation of high-voltage pulses. (a) Image of the striking mechanism (hammer action) found within the piezo igniter in a lighter (arrow indicates location of crystal) (i). The parts include, from top to bottom, metal conductor (gold-colored region) housing the piezoelectric crystal, springs, hammer, release spring and geometrical latch (ii). The presence of two springs is to decouple the loading and release phase for consistent voltage output. (b) Images of the hammer and PZT crystal. The circular surface area of the hammer comes into direct contact with a pin that strikes the piezoelectric crystal, generating a voltage through the piezoelectric effect. (c) Snapshots from high-speed video illustrating the position of the hammer during the loading, latch-release and relaxation phases (i). Free-body diagram indicating movement of each part through each phase of the hammer action, including activation and deactivation of spring forces (ii). (d) Plot of displacement of the hammer and the lower case as a function of time obtained using high-speed image video. (e,f,g) Zooming into the dynamics of the hammer during the latch-release phase reveals that the hammer achieves a peak velocity of 8 ms1 in 0.5 m/s, which corresponds to an acceleration of 30,000 m/s2. The explosive acceleration results in a 10-N force (mass of hammer is 0.3 grams) exerted over a tiny area of the PZT crystal. (Source: Georgia Tech)

Noted M. Saad Bhamla, assistant professor in Georgia Techs School of Chemical and Biomolecular Engineering, One of the fundamental reasons this device works is that the piezoelectric crystal produces a consistently high voltage, independent of the amount of force applied by the user. Our experiments showed that the hammer in these lighters is able to achieve acceleration of 3,000 gs, which explains why it is capable of generating such a high burst of voltage.

As a final confirmation of the designs practicality, they shared the design files, sample protocols and digital instructions with research teams at other institutions, who were then able to build and use their own low-cost, DIY electroporators.

A detailed schematic, BOM, links to component sources, assembly instructions and related documentation for the ElectroPen device project are in their published paper or being made available along with the files necessary for creating a 3D-printed enclosure. The paper ElectroPen: An ultra-lowcost, electricity-free, portable electroporator, published in PLOS Biology, closes with a realistic assessment of the capabilities and limitations of this device compared to commercial ones. The Supplemental Information available via the same link also includes numerous text and video files covering design, test, and evaluation. The project was supported by the National Science Foundation and the National Institutes of Health.

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Composite Thermoelectric Generator Material Easily Flexes and Stretches - Machine Design

Chromatography Resins Market to Witness Rise in Revenues During the Period 2015 2021 – Cole of Duty

Posted on July 21, 2020 by Danzig

The impact of COVID-19 pandemic can be felt across the chemical industry. The growing inability in the production and manufacturing processes, in the light of the self-quarantined workforce has caused a major disruption in the supply chain across the sector. Restrictions encouraged by this pandemic are obstructing the production of essentials such as life-saving drugs.

Chromatography resins are used in the purification and separation of proteins and other bio-molecules in biotechnology, pharmaceutical, food manufacturing, and environmental analysis.Chromatography resins are of three types: Synthetic, natural and inorganic media. Natural polymers include agarose, cellulose and dextran, among others, while synthetic resins include ion exchange resins. The natural and synthetic typesare the more preferred chromatography resins as compared to inorganic media. Chromatography resins are used in affinity, mixed-mode, ion-exchange,hydrophobic interaction and size exclusion techniques.In terms of revenues,Protein A resins accounted for the highest share of the market.In technology terms, ion-exchange chromatography witnessed the highest consumption in the past few years. On the other hand, affinity chromatography resins held the key share by revenue largely due to the higher selling costsassociated with affinity resins

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The main driver for the chromatography resinsis huge demand for monoclonal antibodies.There has been a huge demand for monoclonal bodies owing to a growing number of critical diseases resulting in thesetypes of therapeutics to swiftly gain significance.Food analytics is also one of the major drivers for the chromatography resins market. Chromatography resins are used in nutraceuticals and nutritional chemistry. Chromatography resins are used to detect food additives (adulteration) which has been major issue in the food industry. Biotechnology & pharmaceuticals are the leading end-users for chromatography resins and are likely to gain more importance in the near future.Chromatography resins are also used in industrial applications such as water treatment and environmental analysis. Some of the academic uses of chromatography resins are in genetic engineering and drug recovery which can provide various opportunities for the chromatography resins market. In spite of numerous applications, regulations associated with these applications can act as a major restraint for the chromatography resins market in the coming years.

In terms of demand, North Americawas the leading region for the chromatography resinsmarket. The demand in this region was mainly driven by biotechnology and pharmaceutical applications. The U.S. exhibited a major demand for chromatography resins and this regions increasing health expense trendshave been indirectly driving the market for chromatography resins.Europe was the other leading market for chromatography resins in the past few years and is expected to show good growth numbers over the near future. Pharmaceuticals and food analytics were the major applications for the chromatography resins in this region. The major European countries such as Germany, UK, France and Italy were the major consumers of chromatography resins in the past decade. There is currently a huge demand for chromatography resins in Asia Pacific, particularly from China, South Korea and India due to the growing pharmaceutical industry in these countries.Additionally, the emergence of CMOs and CROs is further driving the chromatography resins market in the Asia Pacific region. The Rest of the World is likely to exhibit stable demand for chromatography resins market over the forecast period. South America and The Middle East region are anticipated to be the potential markets for chromatography resins.

Some of the key players in the chromatography resins market are Bio-Rad Laboratories Inc., GE Healthcare Life Sciences, Tosoh Corporation, Merck KGaA, Life Technologies Corporation, Repligen Corporation, and Pall Corporationamong others.Lower prices with higher productivity and new innovative products had been the key strategies for the manufacturers to gain the competitive advantage in the market. Life Technologies is expected to unveil POROS chromatography resins in Biopharmaceutical Development & Production Week Conference (BPD) to be held in California. Purolite International Ltd. announced its plans to develop bio-separation chromatography resins based on the agarose media. The new product line is likely to meet growing demand of the biomolecules market.

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Chromatography Resins Market to Witness Rise in Revenues During the Period 2015 2021 - Cole of Duty

Brave New World is looking pretty good, all things considered – ZDNet

Posted on July 21, 2020 by Danzig

New London, the backdrop of Brave New World

In 1932, British novelist Aldous Huxley published Brave New World, considered by many to be the seminal work of modern dystopian science fiction in the English language. Along with Mary Shelley's Frankensteinand then, later, George Orwell's Nineteen Eighty-Four, these nightmarish masterpieces have given society pause on the dangers of technological progress throughout the decades and have become part of many high school and college literary reading lists.

At the time of Brave New World's publication, the world was still recovering from the horrors of the 1918 pandemic and World War I, each claiming millions of lives. Society had entered an age of mass industrialization, pioneered by Henry Ford's assembly line. These developments, along with the emergence of the Soviet Union under Joseph Stalin's dictatorship, created a perfect backdrop for Huxley to create his dystopian future, one of a single world state, with no privacy, no individuality, no families, and no self-determination.

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Huxley's future takes place in 2540 AD. Its test-tube gestated, genetically engineered citizens are fed an endless supply of mood-stabilizing drugs. They are kept happy with all forms of sensory distractions, including non-stop sexual activity. It frightened and titillated the public in 1932and, perhaps, still does.

There have been several attempts to update Brave New World in television and film. However, the original work, when adapted, hasn't resonated particularly well with most audiences. As with Nineteen Eighty-Four, which took the idea of the world state, conformity, and mind control even further, it is a depressing, emotionally taxing tale. But it remains an essential, even foundational work of literature that others have shamelessly copied over the almost 90 years since its initial release.

We have seen echoes of the novel's dystopian themes in later works of film and television: THX-1138, Logan's Run, Brazil, The Fifth Element, The Matrix, Minority Report, GATTACA, Equilibrium, The Island, The Hunger Games, Elysium, Westworld, and so many others.

Brave New World has finally gotten the update it deserves with the launch of NBCUniversal's Peacock streaming service, in the form of a nine-episode seriesthat expands upon and diverges from the original work. It even leaves open the possibility for a second season. The cast and characters are all outstanding, and it's well worth watching, especially with the service's free 7-day trial, which you can view on your web browser, mobile devices, and other supported hardware.

As with the original work, civilized society appears to be controlled by a single world government. Its citizens are kept in a state of constant emotional bliss by the use of "Soma," the generic pharmaceutical that appears to be infused in all the food and drink the citizens consume. It's the ever-present nonpareil candy that drops out of each citizen's Pez-like candy dispensers, which make their appearance with unnerving spring-loaded, double-clicking sounds in virtually every scene. They pop it, effortlessly, like Tic-Tacs. And they never run out.

Doors do not have locks, and everyone is fitted with an augmented reality contact lens "Optic" that provides the ability to recognize one another's status (signifier) as well as experience the life-logs and intimate thoughts and feelings of any individual, on-demand, connected to a network and decentralized AI known only as "Indra."

All citizens have and know their place in life, predetermined at conception, which is done artificially and using genetic engineering to determine intelligence level. Children are conceived in a laboratory rather and are raised and "conditioned" by the world government rather than growing up in a family environment.

Also:2084: What happens when artificial intelligence meets Big Brother

On the surface, it does sound awful. Except that there are too many upsides to ignore.

Let's begin with Soma. Sure, everyone is on drugs, but it's not like anyone is nonfunctional and can't go to work the next day after partying with it the night before. Nobody ever gets truly upset or completely emotionally distraught. At least in this TV version, it doesn't appear you can overdose on regular use of Soma (although there is an allusion to a "Soma Red" for euthanasia), nor does it appear to be physiologically addictive because nobody seems to go through withdrawal when they stop using it. It works instantly, and it appears to have a relatively short half-life. It's like super-CBD. Sign me up, tomorrow, on Amazon Subscribe and Save.

Compare this with benzodiazepines like Xanax and related drugs like Valium and Klonopin, which have been a first-line psychiatric medication for treating anxiety and depression for over five decades. Benzos, unlike Soma, create a physiological dependency to the point where discontinuing their use can result in seizures if not correctly weaned off.

Selective serotonin reuptake inhibitor (SSRI) drugs like Zoloft can cause debilitating side effects, including sexual ones. Can they help people? Sure. They're particularly useful for treating acute conditions and short-term issues, but withdrawal is also a problem.

The citizens of New London seem to have no dysfunctions at all. Not only are they incredibly sexually active (to the point of it being their primary source of entertainment, because "everyone belongs to everyone else" and after-hours life, night after night, is one big party), but everyone seems to be in perfect physical shape, attractive, and they never grow old. Violence and crime of any sort are unheard of, and are remnants of the "before times."

Oh yes, people do die, and there are a few scenes that discuss death and how people cope with it (spoiler: they don't have to), but it's never fully explained just how long people can live. Many citizens appear to live to at least a hundred years old, and the society's leaders, the Alpha Pluses, when shown, never look a day over fifty. Mustapha Mond, the World Controller, looks like she could be maybe 55 -- but we never really know just how old. She could be as much as two centuries old based on what is revealed in later episodes. So, medical technology in this society is absolutely top-notch (at least by 20th century standards).

Seriously, given the COVID-19 hellscape we are now living in, I'll take it.

Let's get into the world of New London itself -- it's so freaking clean, with beautiful open-air modern architecture that looks like Star Trek and Logan's Run had a love child, with none of the Trantor-esque downsides of futuristic overpopulated cities we've seen in Blade Runner, Judge Dredd, The Fifth Element, or Star Wars.

Gorgeous, huge towering white buildings, advanced public transportation systems, silent flying autonomous driven vehicles, beautiful public outdoor spaces with greenery, all interspersed with the technology. And absolutely no pollution whatsoever; it's always crystal clear even when it inevitably rains in New London. If you get bored with your surroundings, they have rocket ships that will take you on a sub-orbital parabolic flight to the other side of the planet, Virgin Galactic-style, in less than 15 minutes. Citizens can visit the "Savage Lands" theme park in New Mexico and view Epcot-like re-enactments of what life was like before everything became perfect and clean, in all their trailer park glory.

I'm trying to come up with a potential downside to this, and I can't.

Did I say it was clean? It's so spotless that, when people occasionally drop their Optic Interface contact lenses on the floor, they put them right back into their eyes! Who doesn't want to live in an environment like that? Everyone also has their own gorgeous, spacious condo -- well, at least if you are an Alpha or a Beta. But even the lowly Epsilons get their own single bedroom apartments and their needs are taken care of. Have you ever tried to rent an apartment in San Francisco on even a $200,000-per-year salary without a roommate? Yeah.

But that caste system. Oh yes, let's not forget about that. Society is led by a small number of Alphas, who are engineered to be smarter than the Betas (who, in addition to making up most of the skilled workforce, are there for everyone's sexual pleasure, because monogamy is taboo and considered destabilizing). Society would fall apart without the blue-collar Gamma servants, the Delta proletariat, and lastly, the Epsilons, which are clones with no emotional state whatsoever and do all the lousy menial labor (but, interestingly, get to live out in the verdant English countryside, which Alphas and Betas never see).

Yes, a caste system sounds terrible, but in this world, nobody is truly upset about their place in life, and everyone knows from early childhood based on the conditioning that they have a purpose. In some ways, that's better than billions of people on this planet who live short, unfulfilled lives in complete squalor and despair. And, yes, the idea of being raised by the state in high-tech orphanages is hideous, except when you compare that possibility with the fate that will befall hundreds of millions of children on this planet who grow up with no care at all, discarded, despite many having known who their parents were.

We should also point out that on the TV show, yes, there are castes, but (in an important departure from the novel) there's also no racism whatsoever. Races appear to be well-distributed across all the ranks -- World Controller Mond herself is a black woman. There's also no sexism; women are equal to men in seemingly every profession and also appear to occupy positions of significant societal importance.

Additionally, there are no moral implications or judgment applied to any form of sexual congress between people of any identity, either. Although it is not readily apparent that a concept of "trans" or "queer" even exists in this world, that's something they appear to have weeded out of us. Everyone consents, everyone gives themselves to everyone, when it is asked. When your average person attending a public orgy physically looks like they came out of the Sports Illustrated Year 2540 swimsuit calendar, why not? I doubt that these people even smell unpleasant after their fierce rounds of racquetball.

What may have been viewed as horrifying, repulsive, or shocking in 1932 sounds pretty liberating in 2020, as so many people are still struggling to be accepted just because of who they are and what they want to be, and who they want to be with. I'm not suggesting that life should be a Huxleyan orgy, but how New London's people conduct themselves as it relates to each and everyone else's bedroom antics is far more advanced than our version.

We could learn something from what Huxley calls these "decanted" folks, who emerge from a test tube into the world.

Also:Grandpa, tell me about the days before the Great Distancing

What else? There's no organized religion. Unlike the book, in which Henry Ford is worshiped as some sort of prophet, there is nothing worshipped here other than the technology itself. Their "god" is Indra, which fulfills the purpose of social network and an ever-present watchful eye (which everyone can tune into) and even the algorithm that runs and plans society itself.

Then there are all the distractions such as "feelies" (virtual and augmented reality taken to the dimension of physical sensations), all the crappy house-style music with no words, and no works of fiction or art, per se.

It's a society that operates in a Roman orgy-like state with virtually no culture, which is what Huxley viewed socialism and communism to be when taken to the absolute extremes.

But in many ways, we have our own "Indra." We have Facebook and Twitter, which serve as constant distractions and are cancerous sources of misinformation spread, which continuously make people miserable and help to create endless division and strife.

We choose to be endlessly connected to them, and we allow them to influence us, with all sorts of altered versions of the truth. It's true that the citizens of New London have no privacy and are under constant observation. Still, they can get the unfiltered truth anytime they want. That's not the case with our society, where competition for our collective attention originates from a never-ending feed of crap from questionable sources, and academic expertise and science are always questioned.

Whatever else this imagined future society has done to dehumanize itself, it has still managed to erase humanity's absolute worst social evils. We may not have "castes" in the strict Huxleyan sense, but we now have societal division among political, gender, ethnicity, and race-motivated lines that threaten to tear us apart.

Maybe it's time we start thinking about our old dystopias as sources of inspiration to improve our society. Talk Back and Let Me Know.

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Brave New World is looking pretty good, all things considered - ZDNet

Nucleic Acid Isolation and Purification Market Industry is Thriving with Rising Latest Trends by 2027 – Cole of Duty

Posted on July 21, 2020 by Danzig

A competition that is getting higher day by day has kept many challenges in front of the businesses. So, this Nucleic Acid Isolation and Purification Market business research report is a definite source to gain valuable market insights and take better decisions about the important business strategies. This business document endows clients with the information on their business scenario with which they can build business strategies to thrive in the market. This Nucleic Acid Isolation and Purification Market report also provides the details about the market drivers and market restraints for industry that help in understanding rise or fall of the demand of particular product with respect to market conditions.

Global nucleic acid isolation and purification market is expected to rise from its initial estimated value of USD 3292.28 million in 2018 to an estimated value of USD 6512 million by 2026, registering a CAGR of 8.90% in the forecast period of 2019-2026. This rise in market value can be attributed to the increasing advancement technological and automation of products.

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Competitive Analysis: Global Nucleic Acid Isolation and Purification Market

Global nucleic acid isolation and purification market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of nucleic acid isolation and purification market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Key Market Competitors: Global Nucleic Acid Isolation and Purification Market

Few of the major competitors currently working in the nucleic acid isolation and purification market are Illumina, Inc. (US), Thermo Fisher Scientific Inc (US), Agilent Technologies, Inc (US), QIAGEN (Germany), Protean (US), Hamilton Company (US), GENERAL ELECTRIC (US), Promega Corporation (US), Biocompare (USA), BiogeniQ Inc (USA), Envigo (UK), LGC Limited (UK), PerkinElmer Inc (US), New England Biolabs (US), Quest Diagnostics Incorporated (US), Synbio Technologies (US), addgene (USA), BD (US), InvivoGen (US), GeneCopoeia, Inc. (UAS), among others. LGC Limited

Global Nucleic Acid Isolation and Purification Market By Product (Kits, Reagents, Instruments), Technology (Column-Based, Reagent-Based, Magnetic Bead-Based), Application (Plasmid DNA, Total RNA, Blood DNA, Genomic DNA, Messenger RNA, Micro RNA, PCR Cleanup), Type (Plasmid Dna Isolation and Purification , Total Rna Isolation and Purification, Genomic Dna Isolation and Purification, Messenger Rna Isolation and Purification, Microrna Isolation and Purification, Circulating Nucleic Acid Isolation and Purification, PCR Cleanup), End User (Academic and Government Research Institutes, Pharmaceutical and Biotechnology Companies, Contract Research Organizations, Hospitals and Diagnostic Centers, Other End Users), Geography (North America, South America, Europe, Asia-Pacific, Middle East and Africa) Industry Trends & Forecast to 2026

Market Definition: Global Nucleic Acid Isolation and Purification Market

Nucleic acid isolation and purification technique is the step in molecular biology studies and recombinant DNA techniques. This technique has extensive applications in the arena of genetic engineering, life science research, forensics and molecular diagnostics. Nucleic acid isolation helps in processing of more sample in less time, minimizes nucleic acid loss ad degradation and increases laboratory efficiency and effectiveness.

According to the US Department of Health & Human Services, in 2016 there were approximately 36.7 million people worldwide living with HIV/AIDS, of these, 2.1 million were children (15 years old).

Market Drivers

Market Restraints

Segmentation: Global Nucleic Acid Isolation and Purification Market

By Product

By Application

By Type

By End User

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Key Developments in the Market:

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Nucleic Acid Isolation and Purification Market Industry is Thriving with Rising Latest Trends by 2027 - Cole of Duty

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