Scientists Had to Rename Genes Because They Confused Microsoft Excel

Genetics research is full of errors because Microsoft Excel reformats some gene names into calendar dates. To fix it, scientists just renamed the genes.

Formatting Error

It turns out that the spreadsheet program Microsoft Excel is a major pain for geneticists. Because some genes have names similar to calendar dates, the program automatically reformats and totally messes up the datasets.

It’s a surprisingly common problem that can have a serious impact on published research, The Verge reports. Because Microsoft isn’t about to update its software to cater specifically to geneticists, scientists ended up changing the names of 27 human genes — such as MARCH1 — over roughly the course of a year and just published new naming guidelines.

Saving Time

Excel can be particularly aggressive about automatically reformatting data. And since these errors need to be corrected twice — by the scientist conducting the research and again by anyone who loads the same data and accidentally triggers Excel to autoformat — some slip through the cracks. According to a 2016 study in the journal Genome Biology spotted by The Verge, about 20 percent of 3,597 genetics papers contained Excel errors.

“It’s really, really annoying,” Quadrams Institute biologist Dezs? Módos told The Verge. “It’s a widespread tool and if you are a bit computationally illiterate you will use it. During my PhD studies I did as well!”

New Rules

With the new guidelines in hand, scientists should hopefully be able to avoid naming new genes anything that might trip up Excel. For instance, MARCH1 is now MARCHF1, and SEPT1 is now SEPTIN1.

Thankfully, the changes were welcomed by annoyed geneticists, The Verge reports, so hopefully the scourge of overeager spreadsheet software will finally be lifted from the field.

READ MORE: Scientists rename human genes to stop Microsoft Excel from misreading them as dates [The Verge]

More on genes: “Like Horoscope Readings!”: The Scammy World of DNA Test Startups

The post Scientists Had to Rename Genes Because They Confused Microsoft Excel appeared first on Futurism.

Link:
Scientists Had to Rename Genes Because They Confused Microsoft Excel

Scientists Are Using The Moon as a Giant Mirror to Search For Aliens

Scientists treated the Moon like a giant mirror to study the Earth's atmosphere, a trick they say could help search for inhabited worlds.

Moon Mirror

Astronomers have a new trick in the hunt for habitable exoplanets, and it involves using the Moon as a gigantic mirror.

Basically, NASA and ESA scientists used the Hubble Space Telescope to capture light that reflected off the Moon after it had traveled through the Earth’s atmosphere, Space.com reports. By studying that reflection of our habitable atmosphere, the scientists suspect they could search for the same chemical signatures in distant exoplanets, indicating the possibility of alien life.

Fresh Air

Typically, when scientists use the term “Earth-like” exoplanet, they’re referring to a world that’s rocky, roughly the same size as our own, and about the right distance from its host star to have a livable temperature. But it’s much harder to tell if these exoplanets actually have atmospheres or are otherwise remotely hospitable.

“One of NASA’s major goals is to identify planets that could support life,” Hubble scientist Allison Youngblood said in a press release. “But how would we know a habitable or an uninhabited planet if we saw one?”

Planet B

That’s why Youngblood’s study, published Thursday in The Astronomical Journal, is so important.

This particular study measured the amount of ozone in the Earth’s atmosphere. Spotting that same chemical signature emanating from an exoplanet would suggest that it may have an oxygen-rich and UV-blocking atmosphere just like ours.

READ MORE: Scientists use moon as a mirror to study Earth during lunar eclipse [Space.com]

More on exoplanets: Scientists Find the Most Earth-Like Exoplanet Ever — And It’s Nearby

The post Scientists Are Using The Moon as a Giant Mirror to Search For Aliens appeared first on Futurism.

Here is the original post:
Scientists Are Using The Moon as a Giant Mirror to Search For Aliens

Human Genetics | Pitt Public Health | University of Pittsburgh

Human genetics is the study of how genetic, environmental, and behavioral factors, as well as their interactions, influence human traits, health, and disease. Public health genetics applies advances in human genetics and genomics to improve public health and prevent disease in diverse populations. Genetic counselors work as members of a health care team, providing information and support to patients with genetic disorders and those at risk for inherited conditions.

The Department of Human Genetics is dedicated to graduate training in human genetics research (including molecular, statistical, and bioinformatics research), public health genetics, and genetic counseling.

The mission of the department is to

Human genetics research has helped answer fundamental questions about human nature and led to the development of effective treatments for many diseases that greatly impact human health. Faculty in the Department of Human Genetics have developed and used genetic methods to investigate the causes and treatment of hereditary and acquired human illness and to understand and explore the impact of genetics on public health, education, and disease prevention.

Pitt Public Health human genetics faculty and students currently are involved in varied research projects, including...

Graduates of Pitt Public Healths human genetics program typically go on to positions in academia or in industry and usually are employed by their graduation dates. Alumni currently are working in academic, government, health care, and commercial sectors, including...

The Department of Human Genetics offers four masters level programs, and two doctoral programs:

See the rest here:

Human Genetics | Pitt Public Health | University of Pittsburgh

What Is a Blockchain? | Digital Trends

Cryptocurrency? Blockchain investing? Bitcoin? These are all buzzwords that seem like a millennial get-rich-quick scheme, but Blockchain is a technology that could revolutionize the global economy in almost every aspect, from healthcare to politics and thats just the tip of the iceberg.

Whether youre simply looking to invest in Bitcoin, trade some Ethereum, or are just intrigued about what the heck a blockchain actuallyis, youve come to the right place.

Anthony WallaceAFP/Getty Images

Whileblockchain technology isnt simple when you dig into the nitty-gritty, the basic idea isnt too hard to follow. Its effectively a database thats validated by a wider community, rather than a central authority. Its a collection of records that a crowd oversees and maintains, rather than relying on a single entity, like a bank or government, which most likely hosts data on a particular server. A physical database kept on paper could never be managed by tens of thousands of peers, but thats where computers, and the internet, come in.

Each block represents a number of transactional records, and the chain componentlinks them all together with a hash function. As records are created, they are confirmed by a distributed network of computers and paired up with the previous entry in the chain, therebycreating a chain of blocks, or a blockchain.

The entire blockchain is retained on this large network of computers, meaning that no one person has control over its history. Thats an important component, because it certifies everything that has happened in the chain prior, and it means that no one person can go back and change things. It makes the blockchain a public ledger that cannot be easily tampered with, giving it a built-in layer of protection that isnt possible with a standard, centralized database of information.

While traditionally we have needed these central authorities to trust one another, and fulfill the needs of contracts, the blockchain makes it possible to have our peers guarantee that in an automated, secure fashion.

Thats the innovation of blockchain, and its why you may hear it used to reference things other than Bitcoin and other cryptocurrencies. Though generallynot used for it yet, blockchain could be used to maintain a variety of information. An organization called Follow My Vote is attempting to use it for an electronic voting system thats more secure than modern versions, and healthcare providers might one day use it to handle patient records.

Although blockchain technology has only been effectively employed in the past decade, its roots can be traced back far further. A 1976 paper, New Directions in Cryptography, discussed the idea ofa mutual distributed ledger, which is what the blockchain effectivelyacts as. That was later built upon in the 1990s with a paper entitled How to Time-Stamp a Digital Document.It would take another few decades and the combination of powerful modern computers with the clever implementation with a cryptocurrency, to make these ideas viable.

Data security is failing and there has to be a better system. Blockchain creates a secure, unalterable public record and is poised to dramatically improve the world around you, from voting systems to rental contracts.

In order to validate the blocks in the same manneras a traditional private ledger, the blockchain employs complicated calculations. That, in turn, requires powerful computers, which are expensive to own, operate, and keep cool. Thats part of the reason that Bitcoin acted as sucha great starting point for the introduction of blockchain technology, because it could reward those taking part in the process with something of financial value.

Bitcoin ultimately made its first appearance in 2009, bringing together the classic idea of the mutual distributed ledger, the blockchain, with an entirely digital currency that wasnt controlled by any one individual or organization. Developed by the still anonymous Satoshi Nakamoto, the cryptocurrency allowed for a method of conducting transactions while protecting them from interference by the use of the blockchain.

Although Bitcoin, and alternative currencies, all utilize blockchain technology, they do so in differing manners. Since Bitcoin was first invented it has undergone a few changes at the behest of its core developers and the wider community, and other alt-coins have been created to improve upon Bitcoin, operating in slightly different ways.

In the case of Bitcoin, a new block in its blockchain is created roughly every 10 minutes. That block verifies and records, or certifies new transactions that have taken place. In order for that to happen, miners utilize powerful computing hardware to provide a proof-of-work a calculation that effectivelycreates a number which verifies the block and the transactions it contains. Several of those confirmations must be receivedbefore a Bitcoin transaction can be considered effectivelycomplete, even if to the sender and receiver the Bitcoin is transferred near-instantaneously.

This is where Bitcoin has run into problems in recent years. As the number of Bitcoin transactions increases, the relatively hard 10-minute block creation time means that it can take longer to confirm all of the transactions and backlogs can occur. This has lead to the creation of certain off chain solutions like the Lightning Network, which validate transactions less frequently, to provide faster transactions without slowing the rate of confirmations.

Certain alt-coins, geared towards faster transactions, dont have such a problem with scaling. WithLitecoin its more like two and a half minutes,while with Ethereum the block time is just 10-20 seconds, so confirmations tend to happen much faster. There are obvious benefits of such a change, though by having blocks generate at a faster rate there is a greater chance of errors occurring. If 51 percent of computers working on the blockchain record an error, it becomes near-permanent, and generating faster blocks means fewer systems working on them.

Blockchain technology has a lot of exciting potential, but there are some serious considerations that need to be addressed before we can say its the technology of the future.

Remember all that computing power required to verify transactions? Those computers need electricity. Bitcoin is a poster child of the problematic escalation in power demanded from a large blockchain network using that sort of proof-of-work model. Although exact statistics on the power requirements of Bitcoin are difficult to nail down, its footprint isregularly compared to small countries. Thats not appealing given todays concerns about climate change, the availability of power in developing countries, and reliability of power in developing nations.

Transaction speed is also an issue. As we noted above, blocks in a chain must be verified by the distributed network, and that can take time. A lot of time. As of April 2020, the average confirmation time for a Bitcoin transaction can be anywhere from 10 minutes to several hours, depending on whether you pay a premium transaction fee or not. Ethereum is much more efficient, but its average time is around 15 seconds but even that would be an eternity in a checkout line at your local grocery store. Blockchains used for purposes other than cryptocurrency could run into similar problems. You can imagine how frustrating it would be to wait 15 seconds every time you wanted to change a database entry.

These problems will need to be resolved as blockchain becomes more popular. Still, considering were less than a decade on from the blockchains first implementation, it seems likely that were just seeing the start of adoption for this new idea.

Here is the original post:

What Is a Blockchain? | Digital Trends

Solitude and adventure on the Sunshine Coast – The Province

Egmont Adventure Centre takes wildlife seekers to see a colony of Stellar sea lions.Lisa Kadane

You could jump in and swim with them, suggests Lucas Hansen, our guide from the Egmont Adventure Centre, as he guides the boat closer to the colony of Stellar sea lions. Two of them,El Jefe and Jabba the Hutt as theyve been nicknamed,bluff charge each other on their rocky islet in the Malaspina Straight.

I pass, but not because Im intimidated by their size the water in the channel that separates B.C.s Sunshine Coast from Texada Island is downright chilly.

Stellar sea lions, the worlds largest, live in abundance off the Sunshine Coast.Lisa Kadane

Nestled in the southwest corner of mainland B.C. and accessible only by ferry or air, the coastal wilderness stretches 180 km from Hopkins Landing up to Lund. Its split in two by the Jervis Inlet, requiring travellers heading to Powell River or beyond to take another ferry between Earls Cove on the south coast and Saltery Bay on the north coast. Its main artery, the Sunshine Coast Highway, winds through small communities separated by secluded coves and hemmed in by steep mountains robed green in cedar, fir and hemlock.

Hopkins Landing, the jumping off point for the region, is only a 40-minute ferry ride from Horseshoe Bay. It feels an ocean away from the bustle of Vancouver. For families, the Sunshine Coast lures with deserted beaches, tide pools and laid-back, welcoming towns. For the adventurous, numerous pursuits await, from hiking into the solitude of temperate rainforest, to kayaking around tiny private islands just offshore. Here, fresh air, clean water and unspoiled nature are the perfect antidote after months of staying put indoors.

Postcard perfect view from the dining room at the West Coast Wilderness Lodge.Lisa Kadane

What better place to go than nature? asks Paul Hanson, who owns the West Coast Wilderness Lodge in Egmont. People are going to be needing that wilderness healing power.

Start your Sunshine Coast stay by strolling around Gibsons Landing, a seven-minute drive from the ferry terminal. Most of the stores, eateries and attractions have reopened, including the aquarium at The Nicolas Sonntag Marine Education Centre, located inside the Gibsons Public Market.

Theres a lot more relaxation now around the idea of travellers coming over, especially among small business owners says Stephanie Heins, who owns the Drift Caf and Bistro in Gibsons Landing.

Be sure and stop in to Mollys Reach, a 1926 historic building on the waterfront that gained fame as the set of the Canadian TV classic The Beachcombersits a good place to get beer-battered fish & chips made with Pacific cod. For a glass of B.C. wine with a view of neighbouring Keats Island across the water, you cant beat the patio at the Drift.

Gibsons Landing.Chris Thorn Photography / Sunshine Coast Tourism

A scenic 25-minute drive that rolls through forest and alongside the placid water of the Georgia Straight brings you to Sechelt. Spend time at the tems swiya Museum to learn about the local shshlh Nation, or stop for beachcombing at Porpoise Bay Provincial Park, just north of town. There, a playground and picnic tables complement an inviting, sandy beach with a marked swimming area for kids.

Continue north for another hour to Egmont, a tiny hamlet with just 70 permanent residents and a downtown population of two. There are no trendy boutiques or bistros here, but the West Coast Wilderness Lodge (with an on-site restaurant), makes a good base for exploring the coast and forest for a few days.

The hike to Chatterbox Falls through old-growth forest.Lisa Kadane

After checking in, its just a kilometre walk or drive to the trailhead for The Skook. Its a four-km one-way hike to Skookumchuk Narrows, where 757 billion litres of water surges between the Sechelt and Jervis inlets during the tidal change. The twice-daily spectacle creates standing waves that attract experienced kayakers, and the easy walk to the rapids passes mossy tree trunks, towering cedars and lush ferns.

You need a full day to boat up to Princess Louisa Inlet, a remote fjord where waterfalls tumble down forested mountainsides and steep granite walls to dissolve in a spray of mist where fresh water meets the sea. Ask the captain to point out First Nations petroglyphs on the cliff walls en route, and keep an eye out for bald eagles overhead and harbor seals bobbing in the calm water.

A boat ride up the Princess Louisa Inlet.Greg Eymundson / Insight-Photography.com

Youll have the forest to yourself, at the inlets terminus, as you follow a winding path through towering fir trees to spectacular Chatterbox Falls. It feels like an alpine sanctuary, but at sea level.

After returning to Egmont, bliss out on the lodges spacious patio and toast natures ability to provide respite.

Getting there: BC Ferries sails regularly from Horseshoe Bay to Hopkins Landing. Face coverings are mandatory on all sailings. (bcferries.com)

Stay: Hike or mountain bike by day, kayak by twilight, and sleep peacefully in a comfortable, ocean-view room at the West Coast Wilderness Lodge. To make trip planning easy, the resort can package meals from its on-site restaurant, and activities through the Egmont Adventure Centre, including a visit to a sea lion colony and a day trip to stunning Princess Louisa Inlet.

Do: Be aware some businesses are operating with reduced hours. Be sure and call ahead or verify hours online.

See the article here:

Solitude and adventure on the Sunshine Coast - The Province

Water, Sand and Plenty of Elbow Room on 8 Wild, Protected Coastlines – The New York Times

The grandmother of American conservation, Mardy Murie, once called the national parks our best idea. And this year, with foreign travel all but canceled, some of these celebrated domestic destinations have reached new heights of jam-packed popularity and that, of course, presents challenges during a pandemic.

Despite the breathing room offered by the Great Outdoors, many of the 419 National Park Service areas have sites that are not conducive to social distancing. Many parks concentrate the public along narrow trails leading to crowded geysers, waterfalls, wildlife-viewing stands or other scenic vistas.

Yet there are notable exceptions. In particular, 13 national seashores and lakeshores offer a completely different experience. While these federally protected coastlines collectively attract millions of visitors each year, the primary attraction is water and uncrowded stretches of sand that invite picnics, water activities and social distancing.

During the pandemic, many of the visitor centers, museums, historic buildings and signature lighthouses have remained closed to the public.

The plan, according to the National Park Services administrative history about the seashore surveys of the 1930s, was to protect natural locations for beachcombing, surf bathing, swimming at protected beaches, surf and sport fishing, bird-watching, nature study, and visits to historic structures.

First on the roster, in 1937, was Cape Hatteras National Seashore: 70 miles along North Carolinas Outer Banks, including three lighthouses (the site wasnt formally dedicated until 1958). Prompted by burgeoning development along the coastlines after World War II, Congress added nine more national seashores to the Park Service in 10 different states, along with four national lakeshores in three states surrounding the Great Lakes (Indiana Dunes National Lakeshore was recently changed to a national park). Today these 13 expanses of lake and sea shorelines protect 809,000 acres, abutting thousands of miles of oceans and lakes.

The principal focus of the seashores and lakeshores is recreation. Many of the sites also allow off-road vehicles and sport hunting activities that are forbidden in national parks. And while the heat of summer makes these wild shores ideal destinations, most can also be explored throughout the fall and winter.

From California to Cape Cod, here are eight of the most scenic seashores and lakeshores in the National Park Service.

On a map, Cape Cod National Seashore, established in 1961, resembles the flexed forearm of Cape Cod, Mass., stretching 40 miles from its elbow to its fist, a peninsula punching into the Atlantic Ocean. Half of its 43,000 acres are water. Henry David Thoreau often walked and swam here in the mid-19th century, calling the autumn landscape so beautifully painted It was like the richest rug imaginable.

As one of the most popular seashores, with over four million visitors last year, this seashore has still plenty of room along 15 different beaches to spread out and fish, body surf, swim, go for interpretive walks, take four-wheel drives along the beach and hike a dozen different trails that lead to forested wetlands and picnic areas. Beaches are essential ecosystems that support a wide variety of often overlooked plants and animals, from small nematodes (simple worms) to tiny crustaceans and other clam-like invertebrates living between the lower surf and the higher grasses. You can also observe ospreys, foxes, coyotes and wildflowers amid the rolling dunes. For the summer of 2020, the two visitor centers, half a dozen lighthouses and historic buildings are closed.

Immediately south of Ocean City, Md., this windswept and pristine island stretches 37 miles into Virginia, where it adjoins one of the richest birding sanctuaries in the country, Chincoteague National Wildlife Refuge. The island is also famed for a herd of some 150 wild ponies, ancestors of the animals shipped over by planters in the 1600s. Sometimes they can be seen trotting along (and into) Chincoteague Bay.

Most of the beaches are open to four-wheel driving (with permits), along with biking, hiking, surfing, swimming, kayaking, clamming and fishing. Presently, the visitor center and backcountry campsites are closed. Since this is the only nature-oriented national park site on the Mid-Atlantic seaboard, more than two million people come each year, but in the cool spring and fall, the tourist crowds thin.

Directly south of the often-congested Cape Hatteras, N.C., the scantly visited, 56-mile-long Cape Lookout National Seashore bridges three unspoiled barrier islands: North and South Core Banks and Shackleford Banks. Less than half a million people made brief visits last year. Home to wild horses, nesting loggerhead turtles and countless shorebirds, this undeveloped seashore is accessible only by boat, with no roads or stores. Primitive cabins can be rented on the South Core Banks, while camping is allowed throughout the seashore. The Cape Lookout Lighthouse is closed until further notice.

Otherwise, surf-casting is popular, along with hunting, shell collecting, windsurfing, kayaking, motor boating (like most national seashores, areas for personal watercraft and Jet Skis are limited), long beach strolls and four-wheel driving on the two Core islands (scheduled ferries transport motor vehicles).

As the least visited and most isolated national seashore (53,904 people came in 2019), the 18-mile-long Cumberland Island, off the Georgia coast, showcases an unusual landowner history. Historic structures, such as the Thomas Carnegie mansion ruins, surround what were once thriving cotton plantations. The north end of the island, home to an African-American community in the 1890s, holds the intact First African Baptist Church, which is still a popular destination.

Today, although there are private property owners living on the island, many of the dunes and surrounding beaches have been reclaimed by nature; nearly one-third of the total 36,000 acres are protected wilderness (Cumberland Island National Seashore was established in 1972). Along with feral horses, there are rattlesnakes, alligators, more than 300 species of birds and white tail deer. Fishing, boating and camping opportunities abound; after storms, try your luck hunting for sharks teeth and shells on the beaches.

Largest of all the national seashores at 135,600 acres, with over five million visitors a year, Gulf Islands National Seashore offers plenty of room to go beachcombing and boat across 12 different units that are spread from the Gulf shores on the Florida Panhandle to Southern Mississippi. Eighty percent of the park is water. And the beaches, with their pure white sand, are heralded as among the most beautiful in the world. These crushed quartz shores are likened to spun glass, the grains of which have washed down over thousands of years, from the Appalachian Mountains and into the Gulf.

In addition to sunbathing, swimming or picnicking, youll find year-round snorkeling and scuba diving throughout the warm and pellucid waters, along with ample opportunities to camp, hike, bike, ride horses and hunt. The diversity of wildlife habitats from dunes to marshes to forests attracts more than 300 species of birds, along with armadillos, black bears, dolphins and river otters. Many come to visit the islands four intact forts (the Fort Barrancas area is currently closed) that were built to protect the mainland during the War of 1812.

Renowned as the largest undeveloped barrier island in the world, the drivable hard sand of Texass Padre Island sweeps 80 miles from Corpus Christi to Brownsville, free of the resorts and homes strung along the mainland several miles west across the Intracoastal Waterway. One sheltered stretch, Laguna Madre, contains some of the most saline waters in the world. Padre Island is also known as a windsurfing destination, but when the breeze dies, or out among the sheltered dunes, mosquitoes can be fierce.

Although busy on weekends and during college breaks, most visitors drive in four-wheel vehicles at least five miles south from park headquarters until theyve found the desired isolation. Last year, more than half a million people visited the park. Along with innumerable activities on beaches colorful with evening primrose, there are several shipwrecks buried offshore. For birding opportunities, bring your binoculars, and if patience prevails, wildlife watchers might also get a glimpse of the endangered Kemps ridley turtle.

Five miles wide and 42 miles long, Pictured Rocks hugs the brisk waters of Lake Superior on Michigans scantily populated Upper Peninsula. Taking advantage of the parks lack of entrance fees, more than 800,000 visitors came last year to walk or snowshoe 100 miles of trails, ice climb, camp, ice fish, picnic, hunt, boat and swim. The park is named after its spectacular and multihued limestone cliffs, towering directly above the lake for 15 miles and frothing with waterfalls.

There are also half a dozen beaches easily reached from the road, stretching as long as 12 miles, along with several more isolated beaches to hike into. The shoreline bristles with hardwood forests that blush in brilliant reds and golds during autumn foliage.

As the only national seashore on the West Coast, the spectacular Point Reyes on the San Andreas Fault is a short drive north of San Francisco. In 2019, more than two million people visited this 71,000-acre headland. Home to more than a thousand species of plants and animals, Point Reyes is the most biologically rich and diverse seashore of them all. With forests sheltering tule elk, pastoral grasslands and tall cliffs overlooking the breakers, visitors can watch migrating gray whales, seals and fluttering colonies of seabirds. An astonishing 480 different species of birds have been identified here. In 1988, UNESCO included Point Reyes in the Golden Gate Biosphere Reserve.

Historically, the park preserves the regions 150-year-old cattle-ranching legacy, with dairy operations still active today on the treeless plain above the sea. And down below, in 1579, Sir Francis Drake became the first European to land in California, in what is now called Drakes Cove. The 80 miles of shoreline hold a dozen different beaches the most popular destinations for backpacking, surfing, kayaking or simply strolling along the littoral where the vast Pacific beats the shore.

Follow this link:

Water, Sand and Plenty of Elbow Room on 8 Wild, Protected Coastlines - The New York Times

How to Cross the Threshold into Manufacturing Automation – IndustryWeek

The Association for Manufacturing Excellence (AME) defines people-centric leadership (PCL) as a culture in which every day, everyone goes home feeling fulfilled by pursuing excellence and everybody flourishes. All too often, PCL is missing from lean, causing many manufacturers to struggle to sustain long-term continuous improvement. Lean only succeeds when tactical continuous improvement is combined with respect for all people within the organization.

As a manufacturing specialist for the Delaware Manufacturing Extension Partnership (DEMEP), part of the MEP National NetworkTM, I help small and medium-sized manufacturers (SMMs) develop people-centric leaders, which lets them leverage the skills of their employees required for lean success.

Take for example, Justin Tanks, a Delaware manufacturer of large fiberglass tanks. When I first worked with the company, they had begun their continuous improvement journey, but their momentum was running out of steam. By turning their efforts toward creating people-centric leaders, the company was able to build a foundation for continuous improvement and growth for their business.

According to Ed Short, Justin Tankss CEO, PCL training has helped the company:

If these outcomes sound like things youd like to foster at your company, here are five PCL essentials you can use to achieve similar lean success.

One of the biggest lean roadblocks is when management wastes time trying to control other people. People-centric leaders spend their time and energy reflecting and evaluating themselves. They take responsibility for their own behaviors, which in turn influence the behavior of the employees.

Leaders build relationships with and between people. People-centric leaders recognize they dont have all the answers and that they need all the talents from their entire organization. Leaders must get to know the whole person. They must trust their employees and act with humility. Leaders who act with humility inspire trust.

In a people-centric culture, leaders listen more than they speak. They purposely learn and practice how to actively listen. Listening is the most important thing that good leaders do. As noted by Bob Chapman, CEO of the Barry-Wehmiller company, Doing this one thing can profoundly impact an organization. It can set an organization on a path to a better future.

Everybody likes pizza, T-shirts and monetary gifts, but these things do not necessarily make people feel appreciated for their unique contributions. One of the biggest complaints I hear from people in the organizations I work with is that their boss has no idea what they do. Perhaps a simple thank-you would have more impact. Employees need to know their work has meaning and that they are part of something bigger than themselves. People want to contribute and be appreciated, not be controlled and rewarded.

According to Edgar Scheins book, "Helping," when leaders offer correction or provide a solution, employees can feel frustrated, resentful and demoralized. Effective coaching uses a Kata-based scientific way of thinking, which causes people to self-evaluate and engage their minds. It shifts control from the leader to the employee, which results in self-improvement and growth.

How can your managers take advantage of PCL? First, its critical to remember that like any lean journey, leadership is one of continuous improvement. This journey begins with discarding traditional director leadership paradigms in lieu of supportive coaching roles.

Once youre ready, the above PCL essentials can be developed through education, coaching, reflection and practice. This process includes developing systems to support organizational continuous improvement and clearly communicating strategies and expectations across the organization. This is accomplished by using the PCL framework developed by the AME PCL Curriculum Development Team.

The framework includes:

These elements drive growth and prosperity for the individual, the organization, the stakeholders and the community. PCL engages the minds of the entire workforce to drive continuous improvement and achieve greatness.

Looking for leadership support in your organizations lean journey? Contact your local MEP Center to talk to a lean expert or other manufacturing specialists who understand the needs and challenges of smaller manufacturers.

Program Lead, Enterprise Excellence at DEMEP, Lisa Weis is a people-centric, lean/continuous improvement expert with over 20 years of demonstrated success in helping hundreds of public and private organizations achieve their vision and meet their strategic goals. She is also an AME mid-Atlantic board member and is the lead for curriculum development for the AME people-centric leadership initiative. Lisa has a Bachelor of Science Degree in Chemical Engineering, Cum Laude, from the University of Delaware.

Read the rest here:

How to Cross the Threshold into Manufacturing Automation - IndustryWeek

Using Automated Security Protocols Reduce the Cost of Data Breaches, Report Say – Nextgov

Federal agencies face less costly data breaches because they often employ security automation and orchestration practices, according to a security expert.

IBMs annual Cost of a Data Breach report, released July 29, found the public sector worldwide incurred average losses of $1.08 million per data breachthe lowest average cost compared to 17 other industries. The health care industry faced the steepest average loss per breach at $8.6 million, while the overall average was $3.86 million per incident.

Researchers surveyed over 500 organizations between April 2019 and April 2020. They calculated costs using factors such as how much a company spent on detecting and managing the breach as well as losses associated with business disruption and lost customers post-breach.

Wendi Whitmore, vice president of an IBM team working on incident response and threat intelligence, told Nextgov that the U.S. public sector cost is likely higher than average because the U.S. had the highest average cost of a data breach in regional comparisons. Still, she said, agencies at the federal level lead the way on one of the most important ways to reduce costs: automating and orchestrating security.

Anything working under U.S. Cyber Command, which is much of the military, is a fantastic example, Whitmore said. She added the military has been a leader in developing security automation best practices. Whitmore is a former computer crime investigator with the Air Force Office of Special investigations.

This year is the first time the study could observe how automated security practices affect the cost of data breaches, Whitmore said. Over the past 15 years IBM has been doing the study, these practices were too new and not widespread enough to effectively study.

Now you see this huge, fundamental difference in organizations from a cost perspective for those who do have that ability, and those who don't, Whitmore said.

Challenges for government entities like the Defense Department remain higher than those faced in the corporate world, Whitmore said. However, agencies are less likely to lose customers, a main driver of costs when a data breach happens.

But maintaining continuous, automated security across such a large enterprise is still hard. Whitmore said it means there has to be continuous adaptation of security practices.

One organization that has announced it will adapt is the Defense Information Systems Agency, which in July indicated it will move to a zero trust security framework. Whitmore said the zero trust security architecture is consistent with the advice her team at IBM gives to companies regarding how to successfully defend against data breaches.

We're actually advocating to them to move to a model of hey, we actually can't trust anybody. I don't want you to trust any other node in your network, I want you to operate like you're under attack, every day, Whitmore said.

Read more here:

Using Automated Security Protocols Reduce the Cost of Data Breaches, Report Say - Nextgov

Adopting intelligent automation technology in the health service – National Health Executive

06.08.20

Darren Atkins, Chief Technology Officer (Artificial Intelligence & Automation), East Suffolk and North Essex NHS Foundation Trust featured on Episode 11 of NHEs Finger on the Pulse podcast.

What I say to all the organisations I engage with is to forget the technology and come up with: Why do you want to do automation, what are you looking to achieve in the next 12-18 months, and set yourself a progress of work

Those are the words of wisdom of Darren Atkins, Chief Technology Officer (Artificial Intelligence & Automation) at East Suffolk and North Essex NHS Foundation Trust and an experienced head when it comes to automation and intelligent solutions within the health sector.

Technology is already an integral cog in the healthcare machine and the coronavirus pandemic has merely further accelerated this widespread adoption of solutions, as health and care professionals battle to overcome logistical challenges, changes to working patterns and practices and attempt to free up key manhours from time-consuming administrative tasks in order to spend more time with patients.

This is where automation technology can play a major role in Darrens view. Having been involved with integrated automation into his own trust for the past few years, he and his team have managed to free up thousands of hours a month by transferring slow, menial tasks from human workers to robot counterparts.

Does that sound inherently sci-fi? Absolutely.

Yet, it is becoming a reality in places such as East Suffolk and North Essex NHS FT. The technology remains in its early days and, as is the benefits of these more digital technology solutions, continues to be iteratively improved upon regularly and shared between trusts and organisations on the NHS Digital Exchange, a platform Darren had an instrumental role in establishing.

As Darren explains on the podcast too, he has ambitions for the Digital Exchange to extend beyond just health too: Through the Digital Exchange, my future goal is that it shouldnt just be the NHS. It should be the public sector.

A better connected, collaborative network across public services has been sought for years by countless people, organisations and governments and, at least in the field of automation technology, it appears to be becoming a reality. What is essential at these early stages for any successful adoption of automation solutions though is a willingness to engage and be open to the technology.

Whats really important is to establish a culture of engagement from the very outset.

To do so requires assurances that the technology is reliable, safe and represents good value for money; all aspects we discuss in length with Darren on the latest podcast episode.

But, lets just take safety in this instance. One of the biggest fears weve witnessed in recent years is the idea that taking control, or at the very least these administrative processes, away from human workers and allowing robots and algorithms to complete them will lead to greater numbers of errors and mistakes. Yet, as Darren explains, that is largely just a common misconception.

What the robots are doing are [just] replicating what a human does. Now, a robot doesnt make mistakes unless you teach it to make mistakes.

Similarly, when something does go wrong, these solutions can often provide a much more granular audit of the mistake allowing for a more effective and thorough investigation, ensuring the problem does not happen again. Effective, accurate governance in these systems, depending on the tasks they perform, is an essential step of the process too in Darrens eyes to changing the perception of digital, AI and automation technologies.

To listen to the full conversation with Darren, tune into Episode 11 of NHEs Finger on the Pulse podcast:

See original here:

Adopting intelligent automation technology in the health service - National Health Executive

D-dimer Testing Market: Advent of Automated Hemostasis Markers with High Sensitivity Expand Market Potential – BioSpace

Theglobal D-dimer testing marketis fairly competitive and the intensity of competition is in all likelihood will intensify over the years. Transparency Market Research (TMR) notes that the constant influx of end users and the large number of acquisitions taking place in the market will raise the ante higher for several prominent diagnostics companies and niche suppliers. Top players operating in the D-dimer testing market include Thermo Fisher Scientific, Sysmex Corporation, Siemens Healthcare, Helena Biosciences, F. Hoffman-La Roche Ltd., Grifols, S.A., Becton, Dickinson and Company, Abbott Laboratories, Bio/Data Corporation, and Beckman Coulter, Inc.

TMR observes that top players are increasingly focusing on introducing technology-advanced, integrated hematology analyzers for D-dimer testing, in a move to gain a competitive edge over others.

Request Brochure of Report https://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=2398

The global D-dimer testing market stood at US$ 1.9 billion in 2016 is anticipated to expand at a CAGR of more than 4.0% during the forecast period from 2017 to 2025.

D-dimer tests are used for diagnosing conditions related broadly to deep vein thrombosis (DVT), pulmonary embolism, and disseminated intravascular coagulation (DIC). Among all the applications, the demand for the test for diagnosing DVT is prominent. The number of tests for DVT is poised to touch a mark of 86 million by 2025 end, globally. The popularity of the test stems from its cost-effectiveness and effectiveness in diagnosing symptoms of thrombotic episodes.

Request for Analysis of COVID19 Impact on D-dimer Testing Market https://www.transparencymarketresearch.com/sample/sample.php?flag=covid19&rep_id=2398

Regionally, North America holds the sway in the global market garnering the dominant value in 2016. Vis--vis revenue, the regional market will retain its lead throughout the forecast period. A constantly swelling patient base, coupled with the marked awareness of the link between the risk of cardiovascular diseases and thrombotic episodes in patients, is fortifying uptake.

Widespread Application of D-dimer Tests as Initial Screening for Conditions of Thrombotic Episodes boost Market

The global D-dimer testing market is driven primarily by the rising incidence of pulmonary embolism, deep vein thrombosis, and disseminated intravascular coagulation, for which D-dimer stands as the most popular initial diagnostic test. The high mortality of these conditions among patients in developed nations, is a notable factor bolstering the demand for D-dimer test. In this regard, is the high mortality rate associated with DVT in the U.S. The rising morbidity of serious blood clotting disorders and a number of conditions related to thrombotic episodes in worldwide populations is a crucial aspect catalyzing the demand for D-dimer test.

Request for Custom Research - https://www.transparencymarketresearch.com/sample/sample.php?flag=CR&rep_id=2398

Lack of Reliability of Test Results in POC Settings likely to act as Bottleneck to Growth

The substantial number of D-dimer tests in lab settings, particularly in managing symptoms related with venous thromboembolism (VTE), is accentuating the growth of the market. The global demand for D-dimer tests is also getting a robust push from the rising uptake of these tests in the point-of-care (POC) settings. The rising adoption of D-dimer tests in hospitalized patients is also propelling the growth of the market. However, the lack of universal acceptability of these D-dimer tests in POC settings, mainly due to low bioequivalence compared to lab setting, is hindering the global market to reach its full potential.

The market is facing a serious constraint in the application of D-dimer test in elderly populations. At times the insufficient interpretation of the test may lead to erroneous results, hence clinicians need to exercise caution.

Buy D-dimer Testing Market Report at https://www.transparencymarketresearch.com/checkout.php?rep_id=2398&ltype=S

Advent of Automated Hemostasis Markers with High Sensitivity Expand Market Potential

On the other hand, the global D-dimer testing market is witnessing surge in promising avenues owing to the advent of fully-automated coagulation analyzer using D-dimer tests. The adoption of automation has enhanced the efficacy of the instruments and the accuracy of measurements under D-dimer tests. In this context, the advent of highly sensitive hemostasis markers for these instruments augurs well for the market.

Constant technology advances in the hemostasis markers have opened many an exciting avenues for market players. The high sensitivity of D-dimer testing in excluding VTE makes the test popular among clinicians.

Key Takeaways:

About Us

Transparency Market Research is a next-generation market intelligence provider, offering fact-based solutions to business leaders, consultants, and strategy professionals.

Our reports are single-point solutions for businesses to grow, evolve, and mature. Our real-time data collection methods along with ability to track more than one million high growth niche products are aligned with your aims. The detailed and proprietary statistical models used by our analysts offer insights for making right decision in the shortest span of time. For organizations that require specific but comprehensive information we offer customized solutions through ad hoc reports. These requests are delivered with the perfect combination of right sense of fact-oriented problem solving methodologies and leveraging existing data repositories.

TMR believes that unison of solutions for clients-specific problems with right methodology of research is the key to help enterprises reach right decision.

Contact

Mr. Rohit BhiseyTransparency Market Research

State Tower,

90 State Street,

Suite 700,

Albany NY - 12207

United States

USA - Canada Toll Free: 866-552-3453

Email: sales@transparencymarketresearch.com

Website: https://www.transparencymarketresearch.com/

Here is the original post:

D-dimer Testing Market: Advent of Automated Hemostasis Markers with High Sensitivity Expand Market Potential - BioSpace

Red Hat’s Ansible Automation Comes To IBM i – IT Jungle

August 3, 2020Alex Woodie

Big Blue is now supporting IBM i with Ansible, the open source configuration management software developed by Red Hat. By including IBM i and AIX as a supported target in Ansible, companies that run IBM i will be able to remotely configure and manage IBM i and AIX servers using the same Ansible tools and techniques that they use to manage mainstream X86 and cloud server environments.

Ansible was created back in 2012 by Michael DeHaan, the author of the Cobbler provisioning server and co-author of the Fedora Unified Network Controller (Func) framework for remote administration. Its been widely adopted across the Linux community, where it competes with the likes of Chef, Puppet and other remote configuration tools, and today it also supports Windows, cloud, containerized, and virtualized environments in addition to IBM i and AIX through the new content offerings unveiled in July by IBM.

Ansible was developed to provide a lightweight and reliable configuration management system. The only dependencies that it imposes on the servers that it manages are support for OpenSSH (which Ansible uses to create connections) and Python. Ansible uses an agentless approach to control other servers, and unlike other management frameworks, does not require a single controlling machine when it begins its work (although a centralized controlling machine is soon created).

Administrators interface with the software by constructing playbooks, which are based on a control language based on YAML and Jinja templates. These playbooks define the configurations, deployment, and orchestration activities that Ansible will perform on the managed servers. Admins assign each server environment with a specific role, which Ansible can call as tasks.

The configuration framework also supports the creation of standalone modules written in standard scripting languages, like Python, Perl, Ruby, or Bash. Red Hat, which acquired Ansible Labs in 2015, also provides a centralized Ansible environment for enterprise accounts.

Now, IBM i shops can get into the Ansible swing of things. Ansible is a radically simple IT automation system, write IBMers Wang Yun and Zhu Li Jun in a June 2 post on the IBM i Cloud Blog. It handles configuration management, application deployment, cloud provisioning, ad-hoc task execution, network automation, and multi-node orchestration.

With its new offering, dubbed the Ansible Content for IBM Power Systems, IBM is bringing Ansible content to IBM i, where content refers to sample playbooks, modules, and action plug-ins that make specific IBM i routines supported in the Ansible framework.

Currently, IBM supports 20 automations for IBM i with Ansible, which support things like command execution, system and application configuration, work management, fix management, application deployment, etc. By the end of the year, IBM will introduce 50 more automations, for a grand total of 70.

Ansible automation, along with IBM Cloud Paks, are key aspects of IBMs strategy to simplify the management of cloud and hybrid cloud environments on Power.

IBM provides a bit more detail on the GitHub page for the IBM i collection for Ansible. Among the Ansible action plug-ins that are supported on IBM i are things like ibmi_copy (for copying a SAVF file to a remote IBM i node); ibmi_fetch (for fetching objects from the IBM i node); ibmi_reboot (for rebooting [or IPLing] an IBM i node); ibmi_script, for running CL and SQL scripts on IBM i nodes); and ibmi_synchronize (for synchronizing SAVF objects).

IBM provides a list of 35 additional Ansible modules in its IBM i kit that support more detailed actions, such as scheduling a batch job, ending an active subsystem, or restoring a library. You can see the full list here.

The main motivation in supporting Ansible on IBM i (and AIX) was providing a common management interface across Power Systems and open systems environments, says Dylan Boday, the director of offering management for systems, hybrid cloud, and AI solutions at IBM.

At the end of the day, Power has great capabilities and we want to minimize the skills needed to use those and bring consistent and common skills that theyre doing with X86 in their other event, and we really believe Ansible is a key aid in helping our clients achieve that, Boday told IT Jungle recently.

Ansible will allow IBM i and AIX customers to manage Power servers using the same tools as they use to manage X86 environments on prem and in the cloud.

We have over 20 Ansible automation that are certified by Red Hat today, he continued. Well be expanding that by 50-plus more, so 70 in total for us by the end of this year, and theres many more that are open source. Typically Red Hat . . . has a certified version, then you have an open source version. Well have both of those.

IBM has been experiencing a lot of demand for supporting Power with Ansible, at least from the AIX crowd. At one virtual AIX meeting earlier this year, 70 percent of the clients said they were already using open source Ansible, says Steve Sibley, vice president of IBM Power Systems offering management.

The potential to standardize on a single set of skills around Ansible will be a boon for AIX and IBM i shops alike, Sibley says.

If you really think about it, now you need one set of skills, one set of processes, he says. You dont have to have AIX experts, IBM i experts. Youll have to have one or two. But most of your processes can be the same for your entire infraorder, including now through the public cloud, because you use Ansible to deploy, provision your VMs in the cloud as well.

I think its going to be really significant to our client base, as well, as I think it will bring new clients to Power when they say Oh, you mean I dont have to manage this differently? I dont have to go hire a different infrastructure team to manage Power? he says. Its one of the most exciting things I think we have.

IBM i customers can get Ansible in one of two ways: installing the Ansible Galaxy application, or installing directly from open source.

Power Systems Slump Is Not As Bad As It Looks

Some Insight Into Utility Pricing On Entry Power Iron

More Open Source Databases Coming To IBM i

Open Source Is the Future, So Where Does IBM i Fit In?

Excerpt from:

Red Hat's Ansible Automation Comes To IBM i - IT Jungle

Not Everyone Needs 8 Hours of Sleep, New Research Reveals – TIME

For as long as Seemay Chou can remember, she has gone to bed at midnight and woken around 4:30 a.m. Chou long assumed that meant she was a bad sleeper. Not that she felt bad. In fact, sleeping just four hours a night left her feeling full of energy and with free time to get more done at her job leading a research lab that studies bacteria. It feels really good for me to sleep four hours, she says. When Im in that rhythm, thats when I feel my best.

Still, in an effort to match the slumber schedules of the rest of the world, she would sometimes drug herselfwith melatonin, alcohol or marijuana ediblesinto getting more sleep. It backfired. If I sleep seven or eight hours, I feel way worse, she says. Hung over, almost.

Although the federal government recommends that Americans sleep seven or more hours per night for optimal health and functioning, new research is challenging the assumption that sleep is a one-size-fits-all phenomenon. Scientists have found that our internal body clocks vary so greatly that they could form the next frontiers of personalized medicine. By listening more closely to the ticking of our internal clocks, researchers expect to uncover novel ways to help everybody get more out of their sleeping and waking lives.

Human sleep is largely a mystery. We know its important; getting too little is linked to heightened risk for metabolic disorders, Type 2 diabetes, psychiatric disorders, autoimmune disease, neurodegeneration and many types of cancer. Its probably true that bad sleep leads to increased risks of virtually every disorder, says Dr. Louis Ptacek, a neurology professor at the University of California, San Francisco (UCSF). But details about whats actually going on during shut-eye are sparse. We know almost nothing about sleep and how its regulated, says Ptacek.

Some people are morning larks, rising early, and others are night owls, who like staying up late. Those patterns are regulated by the bodys circadian rhythm, a 24-hour internal clock. People can manipulate their circadian rhythm through all kinds of external factors, like setting an alarm clock or exposing themselves to light. But the ideal sleep duration has long been thought to be universal. There are many people who think everyone needs eight to eight and a half hours of sleep per night and there will be health consequences if they dont get it, says Ptacek. But thats as crazy as saying everybody has to be 5 ft. 10 in. tall. Its just not true.

Ptacek and his wife Ying-Hui Fu, also a professor of neurology at UCSF, are pioneers in the relatively new field of sleep genetics. About a decade ago, Fu discovered the first human gene linked to natural short sleep; people who had a rare genetic mutation seemed to get the same benefits from six hours of sleep a night as those without the mutation got from eight hours. In 2019, Fu and Ptacek discovered two more genes connected to natural short sleep, and theyll soon submit a paper describing a fourth, providing even more evidence that functioning well on less sleep is a genetic trait.

The researchers are now collecting data on short sleepers in order to figure out just how rare these mutations are. If we can get a better understanding of why their sleep is more efficient, we can then come back and help everybody sleep more efficiently, Fu says. Among the participants is Chou, who also happens to work at UCSF. One day at a faculty meeting, she and Ptacek chatted about his work. She immediately recognized herself when he described short sleepers. I had never heard of this. But once I started reading about it, it was sort of an epiphany.

Chou doesnt know yet if she has the identified genetic variants. But after the researchers interviewed her about her familys sleeping patterns, she realized her mom is also a short sleeper. I have memories of when I was younger, and my dad being frustrated with her for staying up really late, but she always seemed fine, she says. The researchers took blood samples from both women.

Doctors once dismissed short sleepers like Chou as depressed or suffering from insomnia. Yet short sleepers may actually have an edge over everyone else. Research is still early, but Fu has found that besides being more efficient at sleep, they tend to be more energetic and optimistic and have a higher tolerance for pain than people who need to spend more time in bed. They also tend to live longer. Chou says the first three hold true for her; by nature, she is sunny and positive, and though she often finds bruises on her body, she usually doesnt remember getting them. I find it annoying how much people complain about little physical pains, she says.

So far, these are just intriguing observations. But by studying genetic short sleepers, Fu and Ptacek believe theyll eventually learn lessons for the rest of us. As we identify more and more genes and we think about the pathways in which they function, at some point, a picture is going to emerge, and we will begin to have an understanding of how sleep is regulated in greater detail, Ptacek says. This, they hope, will lead to targeted treatments, like pills or vitamins, to improve sleep efficiency in everyone.

Researchers are also looking beyond sleep to other circadian bodily processes that might benefit from a personalized or targeted approach. While a master clock in the brain acts like a conductor, setting time for the whole body, the rest of the body is like orchestra players with clocks of their own. All your organs have rhythms, says Steven Lockley, an associate professor of medicine at Harvard Medical School who studies circadian rhythms and sleep. Theres a clock in your heart, a clock in the lungs, a clock in the kidneys. Just about everything in the bodymetabolism, hormones, the immune system, reproductive function and the way DNA is translatedis influenced by a circadian rhythm, he says.

And not everybodys is the same. Peoples internal clocks are often hours off from one another, Lockley says. The range of individual differences is much bigger than anyone really understands yet.

The bodys complex clock system has implications for both healthy people and those with medical conditions, and scientists are already seeing glimpses of how they can time certain tests and treatments to get more accurate or potent results. A cholesterol reading, for example, might be affected by what time of day you go to the doctors office, because the liver (which makes cholesterol) has a circadian rhythm. The time of day at which you measure something could make someone look clinically abnormal, even though theyre not, Lockley says.

Medicine might also be more effective if taken at a certain time. Because theyre metabolized in the liver, drugs change their effects throughout the day, Lockley says. Other circadian bodily processes, like cell function, can also affect how medication acts. Early research suggests certain drugsincluding some for colorectal cancer, pain and asthmaperform better or are less toxic when taken at different times of day.

Exercise, which can be as powerful as medicine for some conditions, is good for you whenever you do it. But I do think that the time of day may have an influence, on top of the effects of exercise, on our metabolic health, says Juleen Zierath, professor of physiology at Karolinska Institute in Sweden. In one small study published in 2018 in the journal Diabetologia, Zierath and her team started 11 men with Type 2 diabetes on a high-intensity interval training program. The men exercised either in the morning (around 8 a.m.) or the afternoon (4 p.m.) for two weeks, then switched schedules. The researchers expected that regardless of the time of day, men in both groups would see improvements in blood-sugar levels. But when they exercised in the morning, they actually had slightly higher levels of blood sugar [than baseline], which we didnt expect at all, Zierath says. Its not clear to what extent the type of exercise and other variables matter, but the study provides an intriguing hint that time of day might make a difference for exercise.

Scientific knowledge is nascent when it comes to optimizing testing and treatment by the clock. Our understanding of individual circadian time is even more primitive. But Lockley believes its the key to personalized medicine; he and others are exploring ways to measure a persons internal circadian time through simple clinical tests. Hopefully in the next five to 10 years, youd go to the doctor, give a breath test or a pee sample, and the doctor would know your biological time, he says. Then all your test results and treatments could be based on your real internal time, which is going to be very different between you and me based on our internal clocks.

For now, even the understanding that our bodies often operate according to different clocks is a big scientific advance. Its already changed the way Chou sleeps, lives and works. Ive just become more comfortable with accepting my sleep, she says. She now asks her employees about their sleep schedules to anticipate when each will be at their peak. She also informs everyone about her own abbreviated schedule, so they know she doesnt expect an immediate response to an email she sends at 4:05 a.m. Thats just when my brain is working, she says.

This appears in the August 17, 2020 issue of TIME.

For your security, we've sent a confirmation email to the address you entered. Click the link to confirm your subscription and begin receiving our newsletters. If you don't get the confirmation within 10 minutes, please check your spam folder.

Write to Mandy Oaklander at mandy.oaklander@time.com.

Read the original here:

Not Everyone Needs 8 Hours of Sleep, New Research Reveals - TIME

Letters: Zoom medicine could never beat the stethoscope – HeraldScotland

I COULD not agree more with the sentiments of Dr Hamish Maclaren (Letters, August 4) when he cautioned against Zoom medicine being accepted as the new norm. While at medical school in Glasgow I benefited very much from the teachings of Macleods Clinical Examination and learned that in sitting talking with a patient, checking the rate, rhythm and volume of their pulse while examining the eyes for any sign of anaemia or jaundice can be very helpful signs as to how well or otherwise that person might be.

While video consultations are able to give us some of the clinical picture, I have not yet mastered the art of ascertaining as to whether there are any crackles or wheezes in the chest by way of Zoom rather than by my use of the stethoscope.

Dr Alan Mitchell, Motherwell.

I SHARE the serious concerns expressed by Dr Hamish Maclaren on the subject of "Zoom medicine". The views of a politician temporarily in the post of Health Secretary for England should not be allowed to lead to such a radical change in the nature of the centuries-old traditional relationship between doctor and patient.

Further, I would invite doctors to consider how readily such a definitive change, other than in exceptional circumstances can be equated with part of the Hippocratic Oath, which in a modern version states inter alia: "I will remember that there is art to medicine as well as science, and that warmth, sympathy and understanding may outweigh the surgeon's knife or the chemist's drugs." It is difficult to imagine Zoom medicine generating comparable amounts of those three highly desirable and beneficial elements of the human condition.

Ian W Thomson, Lenzie.

CAN I voice my complete agreement with David Bryson (Letters, August 4) in his comments regarding opening pubs but not gyms?

Sadly this reflects politicians' inability to see beyond short-term problems: the health of the nation has a massive impact on our health services, but that is in the future so why not let someone else sort it out later? Physical health has been shown time and again to improve our medical needs as we age, even to the extent of shortening recovery times post-operations.

So why are pubs opening when only a fantasist would believe that after several drinks customers will adhere to social distancing guidelines? In our tennis and fitness centre in Prestwick we have utilised one of our indoor courts to space out gym machines and exercise classes, so everyone adheres to social distancing and our members' judgment will not be impaired by alcohol. Yet we cannot open. I appreciate there are problems with large gyms, especially those which are unsupervised, but gyms like ours which are constantly supervised by qualified instructors must represent a far lesser risk than certain pub chains.

Until our politicians are willing to face up to the massive hidden costs of obesity and poor physical fitness they will continue to burden the NHS with unnecessary costs.

David Stubley, Prestwick.

I AM sure Nicola Sturgeon is very aware of the obesity crisis, however you do not have to visit a gym to lose weight and stay healthy.

I make sure I have a good healthy diet and I take plenty of (free) exercise by walking, working in my garden, keeping myself busy around the house and not sitting about eating junk food.

I am a fit and healthy 81-year-old and have never visited a gym in my life.

Ellen Japp, High Blantyre.

Continue reading here:

Letters: Zoom medicine could never beat the stethoscope - HeraldScotland

Children, teens, and the safety of psychotropic medicines – Harvard Health Blog – Harvard Health

Medicines prescribed for attention deficit/hyperactivity disorder (ADHD), depression, anxiety, and other mood disorders known as psychotropic drugs have largely been studied in adults. This concerns many parents whose children take these drugs regularly. Studies have most often looked at the effectiveness of these medicines in teens and children. Now a recent systematic review of multiple studies done in children and adolescents offers new guidance on safety for commonly used medicines.

The aim of this study was to comprehensively synthesize current evidence on the safety of four major classes of psychotropic drugs given to children and adolescents. This helps clinicians make decisions when prescribing, and assists in developing well-grounded guidelines. It also helps identify areas needing further research.

The researchers focused on adverse events, such as side effects or other problems, linked to 80 medicines in four categories: antidepressants, antipsychotics, anti-ADHD medications, and mood stabilizers. Altogether, the studies considered data from 337,686 children and teens. Most study participants were taking either anti-ADHD medicines or antidepressants (roughly 149,000 and 121,000, respectively). Smaller numbers took antipsychotics or mood stabilizers (roughly 67,000 and 1,600).

The study looked at safety profiles and common side effects, which were available in the scientific literature for some, but not all of the medicines: 18 antidepressant medicines; 15 antipsychotic medicines; seven anti-ADHD medicines; and six mood stabilizers. While side effects were modest overall, the researchers found the following:

The authors acknowledge that there were limited data about adverse events for many of these medications. Therefore, a more comprehensive reporting of adverse events is necessary in future research on the use of psychotropic medications in children and adolescents. Additionally, long-term and rare side effects are likely underrepresented here, due to the limited availability of longer-term data.

While medication is one of the stronger treatment tools in mental health care, its not the only one. Especially for children and teens, it is essential to approach behaviors holistically by considering biology, psychology, and social and environmental factors. Frequently, medication is combined with other approaches, such as individual therapy, family therapy, and multidisciplinary, system-based approaches like developing an IEP (individualized education program) for school. A comprehensive assessment can guide the care team in making appropriate plans aimed at an optimal outcome.

See more here:

Children, teens, and the safety of psychotropic medicines - Harvard Health Blog - Harvard Health

Partnership produces business innovation grant to be offered as marketing boost – Medicine Hat News

By Medicine Hat News on August 6, 2020.

A business innovation grant in Medicine Hat will now include up to $1,500 for the use of a professional photographer and marketing specialist.

Grant recipients must be registered for ShopHERE powered by Google.

On July 13 APEX Alberta, Medicine Hat and District Chamber of Commerce and Invest Medicine Hat announced their collaboration with the ShopHERE powered by Google program. The goal is to get 250 businesses online this year providing businesses and artists an opportunity to build a digital presence and minimize the economic impact of the COVID-19 pandemic without any additional costs.

Our businesses must be able to expand their businesses online in order to remain competitive in todays world, said Mayor Ted Clugston. We are now able to offer our businesses the support to build an e-commerce website for free and up to $1,500 to create a professional website with local photography and marketing services. We are looking to keep the grant dollars local wherever possible.

A registered business for the program is eligible to receive up to $1,000 that can be used to hire a local Medicine Hat photographer to feature products displayed on the e-commerce website. They may also be eligible for up to $500 for the use of a local marketing firm to guide the photo shoot and provide a promotional strategy for the newly designed e-commerce website.

You can register your business at http://apexalberta.ca/shophere

To apply for the CMHBIG for ShopHERE users, visit the Community Futures Entre-Corp website at:

http://entre-corp.albertacf.com/mhbig

You must be logged in to post a comment.

Here is the original post:

Partnership produces business innovation grant to be offered as marketing boost - Medicine Hat News

How Blockchain can Benefit the Government – CIOReview

The government can use blockchain to increase the security related to personal details of the citizens by gaining their trust and offering transparency.

FREMONT, CA: The reformation that the internet has brought is similar to the one that blockchain carries. But the typical difference between the revolutionary technology is blockchain plays its role in the background, and the internet does it from the foreground.

Blockchain is used in the various industrial sector, and it is also possible to utilize it in the government services and public sector. It can be used to make the governmental offices secure, trustworthy, efficient, and speedy.

However, the digital government based on blockchain will be noticeable in every interaction with the public, which they will have with a decentralized system.

How Can Blockchain Change Government?

Today, the world is witnessing the hyper-connectivity giving birth to numerous data, and it also has brought valuable information about the economy. It shows how the economy is interacting and operating.

Therefore, the continuous economic transformation is forcing the government officials also to become more efficient, real-time, transparent, and cost-effective. With the system, the government can become more citizen related.

However, dealing with this new demand can be challenging for the government because it will transform the bureaucratic government body. This change can be possible by implementing a secured blockchain structure and other elements to the technology. There are various benefits for the government if they apply blockchain in the system.

Developing Trust with Citizens

The trust that the citizens generally have on their government is low at this point, but it is necessary to change the emerging trend of this constant distrust.

The government, along with blockchain and its various features, can use this to solve the issue. The primary element of the blockchain is transparency, and the government can utilize that by permitting the citizens to view and verify the data. It will even allow people to conduct their verification of the claims made by the government.

Safety of Sensitive Data

Today data hacks and stolen identities have become a reality. As the government is the manager of the society, they have become the primary target of hackers all over the world.

In the past few years, there have been many incidents when the government sectors were attacked, and numerous citizen's details and social security numbers got exposed. There were also situations when the government employee's data got compromised.

Another feature of the blockchain-based solution, which is immutability, can help the government offices. It can make an entire nation block-proof. The blockchain data structure increases the strength of the network. It can be done by removing the chance of a single point of failure, and by continuously doing it, the system will become unhackable.

See Also:Top Blockchain Technology Solution Companies

See more here:

How Blockchain can Benefit the Government - CIOReview

Theres One Cloud on Mars Thats Over 1800 km Long – Universe Today

Mars massive cloud is back.

Every year during Mars summer solstice, a cloud of water ice forms on the leeward side of Arsia Mons, one of Mars largest extinct volcanoes. The cloud can grow to be up to 1800 km (1120 miles) long. It forms each morning, then disappears the same day, only to reappear the next morning. Researchers have named it the Arsia Mons Elongated Cloud (AMEC).

The massive extinct volcano that is home to the cloud is Arsia Mons, a 20 km high (12.4 miles) landmark on Mars surface. Mars is too cold for liquid water, so the cloud is made of water ice. Though it looks like it could be a plume from the volcano, its not. All of Mars volcanic activity ceased a long time ago.

The cloud is seasonal, and observers were expecting it around this time of year.

We have been investigating this intriguing phenomenon and were expecting to see such a cloud form around now, explains Jorge Hernandez-Bernal, PhD candidate at the University of the Basque Country (Spain) and lead author of the ongoing study.

This elongated cloud forms every Martian year during this season around the southern solstice, and repeats for 80 days or even more, following a rapid daily cycle. However, we dont know yet if the clouds are always quite this impressive, added Bernal in a press release.

The southern solstice is when the Sun is in its southernmost position in the sky. Since a Martian year is about twice as long as an Earth year687 days compared to 365the seasons last about twice as long. This cloud grows each morning during the season, for about three hours. Then, it disappears.

The extent of this huge cloud cant be seen if your camera only has a narrow field of view, or if youre only observing in the afternoon, says Eleni Ravanis, a Young Graduate Trainee for the Mars Express mission who works specifically for the VMC instrument.

The ESAs Mars Express spacecraft spotted the cloud with its Visual Monitoring Camera (VMC.) While other cameras on orbiters try to zoom in and get as much detail as possible, VMC is different. Its been described as a web cam in space, and its wide angle helps it see things like the cloud.

Luckily for Mars Express, the highly elliptical orbit of the spacecraft, coupled with the wide field of view of the VMC instrument, lets us take pictures covering a wide area of the planet in the early morning, said Ravanis. That means we can catch it!

The spacecraft is on a wide elliptical orbit, which takes it as far as 10,107km (6,280mi) away from the planet. From that distance, it can image the entire planet, and can capture large-scale features like this cloud.

The Martian atmosphere is dominated by carbon dioxide, which makes up over 95% of the atmosphere. Water vapour is only a trace gas, and has high variability seasonally, daily, and spatially. Researchers hope that watching this cloud will help fill in the picture of Mars atmosphere, including how carbon dioxide behaves.

The cloud is an orographic cloud, meaning that its formation is shaped by geography. Theyre common on Earth, where mountain ranges force approaching air to rise. When the air cools, the water vapour condenses and becomes visible.

Arsia Mons is one of the three extinct volcanoes that make up the Tharsis Montes region on Mars, along with Pavonis Mons and Ascraeus Mons. Arsia Mons is the southernmost of the three. To the northwest of those three lies Olympus Mons, the tallest mountain in the Solar System.

The massive Olympus Mons also plays host to clouds of water ice. Those clouds dont form an elongated stream like AMEC does, but theyre still orographic. They form due to Olympus Mons altitude, which is greater than 21 km (13 miles.)

With a human mission to Mars somewhere on the horizon, the planet is being scrutinized more than ever before. Currently, there are six orbiters operating at the planet, and two surface missions. A third surface mission, NASAs Perseverance Rover, is en route to the red planet.

Like Loading...

Follow this link:

Theres One Cloud on Mars Thats Over 1800 km Long - Universe Today

Mars’ Teddy Ruffner turning heads on baseball diamond this summer | Trib HSSN – TribLIVE

By: Greg MacafeeTuesday, August 4, 2020 | 2:33 PM

Courtesy of Louis Scavnicky

Mars senior Teddy Ruffner competes for the Pittsburgh Diamond Dawgz during the 2020 summer season.

Courtesy of Louis Scavnicky

Mars senior Teddy Ruffner competes for the Pittsburgh Diamond Dawgz during the 2020 summer season.

Chaz Palla | Tribune-Review

Mars Teddy Ruffner gains yards outside on North Hills Friday, Oct. 4, 2019 at Martorelli Stadium.

Despite the circumstances surrounding the coronavirus pandemic, Mars senior Teddy Ruffner has stayed busy this summer, and hes making the most of the situation.

The Mars catcher has made up for his lost junior baseball season. He said between the Youngstown Class B league and his Pittsburgh Diamond Dawgz team, hes been playing four or five games per week and is putting on a show while doing it.

The kid is a really good player and he plays at a really high speed, Pittsburgh Diamond Dawgz coach Frank Merigliano said. Hes probably the most physical player that weve ever had in terms of what he brings to the table physically. I mean hes a 6.6 (60-yard dash) runner as a catcher, which is ridiculous, and hes a 195-pound spark plug. He plays the game at an intensity level that you dont see very often.

After his junior season was canceled in the spring, Ruffner figured he would get to play baseball at some point this summer, he just didnt know when it would happen. He expected July or August but as leagues took form, Ruffner was quickly playing multiple games a week.

He also has caught the attention of college coaches, and his recruitment has started to take off. Ruffner said he has several options on the table for his post-high school plans.

(Recruiting) has picked up a lot especially in the last few weeks, Ruffner said. My travel ball coach, Frank Merigliano, has done a great job of getting in contact with coaches and sending them video and texting them and getting my name out there. Ive talked to a lot of schools in the past week or two, just constantly on the phone with coaches and it really has picked up. Its good to have a lot more options right now.

Ruffner said hes talked to some Division I and III schools for baseball. Hes also announced football offers from Carnegie Mellon and Bowdoin College and despite the circumstances, it doesnt look like it will slow down anytime soon.

Since joining the Pittsburgh Diamond Dawgz, Merigliano has seen Ruffners game reach a new level over the past year.

With the work hes put in and all the stuff that weve done, I think he went from being an unknown to a kid that is a legitimate Division I prospect, Merigliano said. When he came to us in the fall, he was still doing football so he was doing as much as he could, but I wasnt sure where he would end up, but I knew the physical part of it was there. But he put the work in, hes elevated his game and hes a different guy than what he was last year. Theres no question.

Ruffner (5-11, 195) carried the ball 263 times for 1,919 yards and averaged 7.3 yards per carry for the Fightin Planets last fall as they made a WPIAL Class 5A playoff appearance.

Ruffner said hes been playing both sports since he was a little kid and knows at some point, hes going to have to pick between the two. But he isnt quite ready to make that decision yet.

Im keeping both options open at the moment, Ruffner said. I want to see after I get all the offers and talk to all the coaches, whatever school is the best fit thats where Im going to go. I dont want to limit any options right now. Ive been playing both sports since I was like 5 or 6 years old so its going to be hard to definitely give up one.

When he does make that decision and if he does choose to play baseball, Merigliano believes Ruffners game could take another giant leap forward when hes focusing solely on baseball.

Once he becomes a full-time baseball player and football is out of the picture, I think youll see another jump, Merigliano said. When it becomes a full-time focus on baseball, I think youll see that next level jump again.

Greg Macafee is a Tribune-Review staff writer. You can contact Greg by email at gmacafee@tribweb.com or via Twitter .

Read more from the original source:

Mars' Teddy Ruffner turning heads on baseball diamond this summer | Trib HSSN - TribLIVE

New SpaceX Starship fails to fire, but the Mars rocket has more chances – CNET

Putting humans in the picture gives a better idea of just how big the Starship orbital prototype will be. SpaceX founderElon Musk shared this behind-the-scenes lookat workers in Texas with Starship on a transporter in September 2019.

Update, Aug. 4., 5 p.m. PT: The hop went off successfully. Read about it here.

SpaceX's latest Starship prototype had another false start Tuesday morning, as a test "hop" of the next-generation rocket was aborted before ignition.

This follows an earlier attempt, Monday evening, in which the engine of the SN5 test model failed to ignite.

Subscribe to the CNET Now newsletter for our editors' picks of the most important stories of the day.

Elon Musk tweeted that crews may try again later Tuesday, but the company also secured backup launch opportunities for Wednesday and Thursday, according to Federal Aviation Administration notices.

Though the roughly 9-story-tall test craft is designed for orbital flight, it'll make an attempt at what amounts to slowly rising in the air to about 150 meters (492 feet).

According to airspace closures issued by the FAA for the area, the hop could still happen Tuesday anytime before 6 p.m. PT.

You might recall that an earlier test craft called "Starhopper" performed such a short flight last year.

Now playing: Watch this: SpaceX aces Starhopper rocket test

2:41

On Thursday, crews at the SpaceX development facility in Boca Chica, Texas, completed a successful static fire of the prototype's raptor engine, clearing the path for a hop attempt.

"Starship SN5 just completed full duration static fire. 150m hop soon," Musk said on Twitter.

Musk said on Twitter lastmonth that SN5 "will attempt to fly later this week," but Hurricane Hanna had other plans, forcing SpaceX to batten down the hatches at Boca Chica and postpone all major tests.

It's been a struggle to get the SN series of prototypes off the ground.

So far, SN4 exploded after a static fire test, SN3 crumpled during a pressure test, and SN1 suffered a similar fate.

This, of course, is why you test. SpaceX suffered a similar string of failures before Falcon 9 launches and landings became a routine thing.

And so the company is pressing forward with Starship.

It's possible we could still see the big silver rocket fly Tuesday. Of course, we've heard this all before. Fingers crossed.

Original post:

New SpaceX Starship fails to fire, but the Mars rocket has more chances - CNET

Mars Hill facility to begin outdoor visits with family – The County

Northern Light Continuing Care (1)

The Northern Light Continuing Care facility in Mars Hill. (David Marino Jr. | The Star-Herald)

The Northern Light Continuing Care facility in Mars Hill. (David Marino Jr. | The Star-Herald)

Northern Light Continuing Care in Mars Hill will begin outside family visitation on Thursday, according to local hospital officials.

MARS HILL, Maine Northern Light Continuing Care in Mars Hill will begin outside family visitation on Thursday, according to local hospital officials.

Visitation at Northern Light A.R. Gould and its outreach facilities was halted in most cases when the COVID-19 pandemic began in late winter, in order to help protect patients, staff and visitors and slow the spread of the virus.

We are thrilled to be able to offer the opportunity for families to come and visit their loved one, said Kelly Lundeen, director of the facility. This has been such a challenging time for our residents and their families, and we are doing all we can to help them reconnect in a safe way.

For now, as a trial period, outdoor visits will be available by appointment only during limited hours Monday through Friday. Family members, up to two people over the age of 10, can visit a loved one for 20 minutes.

At this point, each block of time will be reserved for one family only. Visits will be weather dependent.

To make this successful, it will be important that all involved follow the safety guidelines we have in place, Lundeen said. Our residents are at high risk by nature of their age, their overall health and living in a congregate care environment. We wont be able to continue to allow visits if we cant do so in a safe manner.

Family members who visit will be required to follow safety steps, including: arriving only at the appointed time; being screened upon arrival; sanitizing hands; wearing a mask (both residents and visitors) that cannot be removed during the visit; maintaining a physical distance of at least six feet; and not bringing in food or gifts.

Lundeen said staff will be available during the visits to assist with any tools that may be needed to help visitors and their loved ones hear each other through masks and distance.

For those who might not be able to come in person right now, either because they are not feeling well or have traveled out of state recently, we encourage you to take advantage of other alternatives for staying in touch, said Lundeen.

We have cell phones and iPads for our residents to use who do not have their own. Calls, FaceTime, and Zoom are all great technical options for staying in touch. We have staff who will help residents who are not technically savvy get connected. Window visits are another option, she added. You can be outside of the facility and view your loved one through the window while talking on the phone.

Appointments for visits can be made by contacting Vicki, activities coordinator, at 207-768-4964.

Thank you for reading your 4 free articles this month. To continue reading, and support local, rural journalism, please subscribe.

Original post:

Mars Hill facility to begin outdoor visits with family - The County