Racism In Medicine Isn’t An Abstract Notion. It’s Happening All Around Us, Every Day – WBUR

Ahmaud Arbery. Breonna Taylor. George Floyd. Tony McDade.

For some, their killings illuminate racisms stronghold on our society for the first time. However, police brutality is part of the epidemic of anti-Black racism initiated when the first slave ships docked on American shores in1619.

Racism is part of my daily experience, even as a medical student rotating through the teaching hospitals of Harvard Medical School. The health care system is one sector within the larger framework of white supremacy embedded in American society. While the medical community accepts how the social determinants of health contribute to disparities, we hesitate to address how structural and interpersonal racism shorten Black peoples lives. Medicine has yet to actively become anti-racist.

Our non-Black colleagues must join in the fight for justice to relieve the disproportionate burden on Black physicians.

One experience, in particular, stands out.

As a second-year medical student, I attended a multidisciplinary meeting about whether a young Black woman admitted for a manic episode should be placed inthe locked area of the unit.She had been walking around the unit wearing face paint resembling tribal markings and rapping the lyrics to music about being Black in America. On that basis alone, the floor nurses deemed this 140-pound woman a threat. At the back of the room, I had an internal debate about whether to speak up and note that wearing face paint or rapping is her expression of culture that reflects identity, and not threat. Throughout that meeting, every comment failed to acknowledge the room's overwhelming whiteness and the role structural racism played in this patients mental health and medical care. Eventually, I asked why we did not acknowledge the oppression she faces as a Black woman and explore her resilience. I was simply told she was too sick to engage in that dialogue.Following the larger meeting, I met with my resident for a debrief. He stated the normally unspoken, but widely accepted truth thaton that particular unit, the darker someone's skin, the lower the threshold to restrain the patient.

The medical community largely avoids talking about how systemic racism affects our Black and brown patients individually. We are more comfortable talking about the social determinants of health for marginalized people, collectively, rather than discussing how we disenfranchise the patient under our care. Often, the few minority trainees and providers hold the burden of addressing these issues; they are constantly tasked to speak up for themselves and their communities.

As a Black woman, I am overwhelmed by wearing the hats of cultural mediator and trainee. We are forced to balance providing clinical care while witnessing the discrimination of our patients and ourselves. Additionally, we are asked to address and resolve these issues in a collective manner. The roles of colleague and patient advocate are often at odds as I strive to build strong team relationships but, more importantly, advocate for equity.

It is vital to educate everyone on a clinical team about the power of their implicit bias andmicro-aggressionsthat demean their colleagues and offer disparate patient care. Medical education must equip trainees to interrogate health inequity with acritical race theory framework.Our non-Black colleagues must join in the fight for justice to relieve the disproportionate burden on Black physicians.

Ultimately, that patient was restricted to the locked area of the unit. During a subsequent interaction, she called 911 on her medical team and refused to hang up the phone and return to her room. Because of this, hospital security was called, and they carried her back to her room while she screamed that they should not touch her.

Just one week earlier, a tall elderly white man assaulted three different staff members before being moved to a locked room; security was not called until the third incident.

The stark contrast in their treatment emphasizes how threat is also racialized in our healthcare institutions.

Black women are three to four times more likelyto die due to pregnancy-related causes than white women. Police killings of unarmed Black Americans cause55 million excess poor mental health daysper year among Black American adults, and from 2015 to 2016, on average 286.5 Black boys and men were killed by the police in the United States. Together,they lost 15,673.7 years of life.

It is time to start naming racism, and not race, as a risk factor for disease.

This is a call for the medical community to become actively anti-racist. Health care leaders must acknowledge police violence towards the Black community, and other manifestations of racism, as a public health crisis and implore our public systems for justice. Wemusttake responsibility to address the inequities that shorten Black men and womens life expectancy. We must reckon with medicines history of racism and structural violence. We must reevaluate our medical guidelines and institutional protocols to pinpoint "How is racism operating here?" and propose solutions as it is identified.

It is time to start naming racism, and not race, as a risk factor for disease.

Desmond Tutu famously said, If you are neutral in situations of injustice, you have chosen the side of the oppressor. As a medical community, we face an urgent decision to either speak out and break the stronghold of racial injustices or remain silent and tighten its bondage.

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Racism In Medicine Isn't An Abstract Notion. It's Happening All Around Us, Every Day - WBUR

School of Medicine and Health Sciences to form anti-racism coalition – GW Hatchet

Media Credit: Hatchet File Photo

Medical school Dean and MFA CEO Barbara Lee Bass said the initiative will have a "durable" and "sustainable" impact within the medical school and beyond.

School of Medicine and Health Sciences officials announced the creation of an anti-racism coalition at a recent medical school and Medical Faculty Associates town hall, according to arelease Friday.

The Anti-Racism Coalition will focus on four pillars of anti-racism work, including individual, interpersonal, institutional and structural forms of racism, according to the release. Interim Senior Associate Dean for Diversity and Faculty Affairs Yolanda Haywood who will co-lead the coalition with former National Institutes of Health anesthesiology chief Karen Williams said all members of the GW medical community must engage in anti-racism work.

While the Anti-Racism Coalition will be housed within the Office of Diversity and Inclusion, this work does not belong to any one person or any one group, Haywood said in the release. All of us will be included in this fight, and each of us should take responsibility for anti-racist work.

The idea for the coalition resulted from a grassroots discussion between Haywood and medical school Dean and MFA CEO Barbara Lee Bass following the police killing of George Floyd, according to the release.

Either you are an anti-racist or you are not, Haywood said. And if youre not, then you need to start educating yourself. If you are, then you need to further educate yourself. We are all in this together.

Bass said the initiative will have a durable and sustainable impact within the medical school and beyond.

It is my hope that we use this genuine moment in our history to utilize all of our tools to craft a new normal relative to race, equity, integrity and opportunity, Bass said. A new normal that fights for true equality for all. Weve got a lot of work to do, but it is our responsibility to take advantage of this moment and create something that will make a difference.

This article appeared in the June 26, 2020 issue of the Hatchet.

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School of Medicine and Health Sciences to form anti-racism coalition - GW Hatchet

The Covid-19 pandemic will make medical students better doctors – STAT

When I graduated from medical school more years ago than I care to remember, my training as an intern and a resident followed an unrushed, traditional path. Medical students at the time were introduced to patients gradually, and we took our time engaging with the trying challenges that make up the bulk of a physicians career.

This year, students graduating from the medical school where I am dean and from other schools are facing a very different time line: Due to the Covid-19 pandemic, many of them have been called upon to volunteer or work in hospitals before their time in medical school was over.

Thats not unprecedented. In 1918, some medical students were graduated early to help fight the raging Spanish flu. In 1952, medical students in Denmark helped provide polio patients with round-the-clock manual ventilation. In the 1980s, doctors in training were thrust into the burgeoning AIDS epidemic.

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But none of these match the global shutdown were experiencing now, and the young men and women officially donning their white coats as new doctors will soon realize that the world theyre entering is one profoundly altered by the pandemic.

They will be changed by it, as will medicine.

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As they work at the bedsides of those with Covid-19, new doctors will discover a skill too long ignored by most medical schools: empathy. From my days as a trainee until quite recently, medical education focused almost entirely on increasingly specific specialization. Medical students were encouraged and rewarded for how well they mastered their chosen field, not how kindly they spoke to the frightened person looking them in the eye, eager for a glimmer of good news.

This massive outbreak changes all that, making clear that no matter how great physicians technical skills are, they may not be considered healers until theyve learned how to soothe and inspire, to comfort patients and family members alike (even when its compassionately delivering bad news), to deliver not only treatment but also hope. Working in hospitals packed with patients of all ages and demographics, and tending to those who, due to isolation, cant be with their loved ones, will teach new doctors skills their older peers all too often had to pick up on their own.

As my students and others all across the country make their rounds, they will likely notice that while an infectious disease like Covid-19 afflicts people regardless of race or wealth or education, its impact varies widely based on socioeconomic status. Walking the hospital corridors, physicians in training will notice that patients who exist paycheck to paycheck, or who live in one of the many food deserts that blight even Americas wealthiest cities, are more likely to suffer from heart disease or diabetes and, as a result, are more likely to be harder hit by the virus. They will also notice that many of these are people of color.

Such a realization can and must change everything about the way medical students perceive their profession, as well as everything about the way future generations of physicians are trained. Social determinants, we now know a persons income, say, or ZIP code have a tremendous impact on his or her well-being, which is why death and disease rates can vary wildly even among residents of the same city who live in different neighborhoods.

These data points should no longer be considered incidental, the sort of soft stuff a physician can easily ignore and something that once wasnt taught in medical school. Instead, we should make it a point to ask questions about a patients socioeconomic condition as part of the intake process so we can better understand the fuller picture of her or his life and better help him or her recover.

Finally, beginning a career during a lethal and fast-spreading outbreak will likely do one more important thing to shape the mindsets of this years graduating medical students. The young men and women who gravitate to medicine as a profession often do so because theyre enamored of the scientific method and because they believe in using science to help heal the world. But watching a pandemic ravage the entire planet, leaving hundreds of thousands dead in its wake, is a good but terrible reminder that the scientific method is just that a method, not blind faith and that there are few more crucial and humbling moments in a doctors life than simply saying, I dont know.

While I hope and believe that the brightest minds around the world will soon find treatments for people with Covid-19 and a vaccine to prevent it, I know that helping care for patients in the absence of a cure will teach students humility, an essential trait for all of us but especially for doctors, who are frequently called on to make life or death decisions.

As I watch my students rush into hospital wards well before the ordinary course of their training would have them do so, I find myself inspired not only by their dedication and eagerness to help but also by the knowledge that, as difficult as their path may be, they will emerge from it as better healers, for the benefit of us all.

Lawrence G. Smith, M.D., is the founding dean of the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.

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The Covid-19 pandemic will make medical students better doctors - STAT

Profits and Pride at Stake, the Race for a Vaccine Intensifies – The New York Times

WASHINGTON Four months after a mysterious new virus began its deadly march around the globe, the search for a vaccine has taken on an intensity never before seen in medical research, with huge implications for public health, the world economy and politics.

Seven of the roughly 90 projects being pursued by governments, pharmaceutical makers, biotech innovators and academic laboratories have reached the stage of clinical trials. With political leaders not least President Trump increasingly pressing for progress, and with big potential profits at stake for the industry, drug makers and researchers have signaled that they are moving ahead at unheard-of speeds.

But the whole enterprise remains dogged by uncertainty about whether any coronavirus vaccine will prove effective, how fast it could be made available to millions or billions of people and whether the rush compressing a process that can take 10 years into 10 months will sacrifice safety.

Some experts say the more immediately promising field might be the development of treatments to speed recovery from Covid-19, an approach that has generated some optimism in the last week through initially encouraging research results on remdesivir, an antiviral drug previously tried in fighting Ebola.

In an era of intense nationalism, the geopolitics of the vaccine race are growing as complex as the medicine. The months of mutual vilification between the United States and China over the origins of the virus have poisoned most efforts at cooperation between them. The U.S. government is already warning that American innovations must be protected from theft chiefly from Beijing.

Biomedical research has long been a focus of theft, especially by the Chinese government, and vaccines and treatments for the coronavirus are todays holy grail, John C. Demers, the assistant attorney general for national security, said on Friday. Putting aside the commercial value, there would be great geopolitical significance to being the first to develop a treatment or vaccine. We will use all the tools we have to safeguard American research.

The intensity of the global research effort is such that governments and companies are building production lines before they have anything to produce.

We are going to start ramping up production with the companies involved, Dr. Anthony S. Fauci, the director of the National Institute of Allergy and Infectious Diseases and the federal governments top expert on infectious diseases, said on NBC this week. You dont wait until you get an answer before you start manufacturing.

Two of the leading entrants in the United States, Johnson & Johnson and Moderna, have announced partnerships with manufacturing firms, with Johnson & Johnson promising a billion doses of an as-yet-undeveloped vaccine by the end of next year.

Not to be left behind, the Britain-based pharmaceutical giant AstraZeneca said this week that it was working with a vaccine development project at the University of Oxford to manufacture tens of millions of doses by the end of this year.

With the demand for a vaccine so intense, there are escalating calls for human-challenge trials to speed the process: tests in which volunteers are injected with a potential vaccine and then deliberately exposed to the coronavirus.

Because the approach involves exposing participants to a potentially deadly disease, challenge trials are ethically fraught. But they could be faster than simply inoculating human subjects and waiting for them to be exposed along with everyone else, especially as the pandemic is brought under control in big countries.

Even when promising solutions are found, there are big challenges to scaling up production and distribution. Bill Gates, the Microsoft founder, whose foundation is spending $250 million to help spur vaccine development, has warned about a critical shortage of a mundane but vital component: medical glass.

Without sufficient supplies of the glass, there will be too few vials to transport the billions of doses that will ultimately be needed.

The scale of the problem and the demand for a quick solution are bound to create tensions between the profit motives of the pharmaceutical industry, which typically fights hard to wring the most out of their investments in new drugs, and the publics need for quick action to get any effective vaccines to as many people as possible.

So far, much of the research and development has been supported by governments and foundations. And much remains to be worked out when it comes to patents and what national governments will claim in return for their support and pledges of quick regulatory approval.

Given the stakes, it is no surprise that while scientists and doctors talk about finding a global vaccine, national leaders emphasize immunizing their own populations first. Mr. Trump said he was personally in charge of Operation Warp Speed to get 300 million doses into American arms by January.

Already, the administration has identified 14 vaccine projects it intends to focus on, a senior administration official said, with the idea of further narrowing the group to a handful that could go on, with government financial help and accelerated regulatory review, to meet Mr. Trumps goal. The winnowing of the projects to 14 was reported Friday by NBC News.

But other countries are also signaling their intention to nationalize their approaches. The most promising clinical trial in China is financed by the government. And in India, the chief executive of the Serum Institute of India the worlds largest producer of vaccine doses said that most of its vaccine would have to go to our countrymen before it goes abroad.

George Q. Daley, the dean of Harvard Medical School, said thinking in country-by-country rather than global terms would be foolhardy since it would involve squandering the early doses of vaccine on a large number of individuals at low risk, rather than covering as many high-risk individuals globally health care workers and older adults to stop the spread around the world.

Given the proliferation of vaccine projects, the best outcome may be none of them emerging as a clear winner.

Lets say we get one vaccine quickly but we can only get two million doses of it at the end of next year, said Anita Zaidi, who directs the Bill and Melinda Gates Foundations vaccine development program. And another vaccine, just as effective, comes three months later but we can make a billion doses. Who won that race?

The answer, she said, is we will need many different vaccines to cross the finish line.

At 1 a.m. on March 21, 1963, a 5-year-old girl named Jeryl Lynn Hilleman woke up her father. She had come down with the mumps, which had made her miserable with a swollen jaw.

It just so happened that her father, Maurice, was a vaccine designer. So he told Jeryl Lynn to go back to bed, drove to his lab at Merck to pick up some equipment, and returned to swab her throat. Dr. Hilleman refrigerated her sample back at his lab and soon got to work weakening her viruses until they could serve as a mumps vaccine. In 1967, it was approved by the F.D.A.

To vaccine makers, this story is the stuff of legend. Dr. Hilleman still holds the record for the quickest delivery of a vaccine from the lab to the clinic. Vaccines typically take ten to fifteen years of research and testing. And only six percent of the projects that scientists launch reach the finish line.

For a world in the grips of Covid-19, on the other hand, this story is the stuff of nightmares. No one wants to wait four years for a vaccine, while millions die and economies remain paralyzed.

Some of the leading contenders for a coronavirus vaccine are now promising to have the first batches ready in record time, by the start of next year. They have accelerated their schedules by collapsing the standard vaccine timeline.

They are combining trials that used to be carried out one after the other. They are pushing their formulations into production, despite the risk that the trials will fail, leaving them with millions of useless doses.

But some experts want to do even more to speed up the conveyor belt. Writing last month in the journal Vaccines, the vaccine developer Dr. Stanley A. Plotkin and Dr. Arthur L. Caplan, a bioethicist at NYU Langone Medical Center, proposed infecting vaccinated volunteers with the coronavirus the method known as challenge trials. The procedure might cut months or years off the development but would put test subjects at risk.

Challenge trials were used in the early days of vaccine research but now are carried out under strict conditions and only for illnesses, like flu and malaria, that have established treatments.

In an article in March in The Journal of Infectious Diseases, a team of researchers wrote, Such an approach is not without risks, but every week that vaccine rollout is delayed will be accompanied by many thousands of deaths globally.

Dr. Caplan said that limiting the trials to healthy young adults could reduce the risk, since they were less likely to suffer serious complications from Covid-19. I think we can let people make the choice and I have no doubt many would, he said.

In Congress, Representative Bill Foster, Democrat of Illinois and a physicist, and Representative Donna E. Shalala, Democrat of Florida and the former secretary of the Department of Health and Human Services, organized a bipartisan group of 35 lawmakers to sign a letter asking regulators to approve such trials.

The organizers of a website set up to promote the idea, 1daysooner.org, say they have signed up more than 9,100 potential volunteers from 52 countries.

Some scientists caution that truly informed consent, even by willing volunteers, may not be possible. Even medical experts do not yet know all the effects of the virus. Those who have appeared to recover might still face future problems.

Even without challenge trials, accelerated testing may run the risk of missing potential side effects. A vaccine for dengue fever, and one for SARS that never reached the market, were abandoned after making some people more susceptible to severe forms of the diseases, not less.

It will be extremely important to determine that does not happen, said Michel De Wilde, a former senior vice president of research and development at Sanofi Pasteur, a vaccine maker in France.

When it comes to the risks from flawed vaccines, Chinas history is instructive.

The Wuhan Institute of Biological Products was involved in a 2018 scandal in which ineffective vaccines for diphtheria, tetanus, whooping cough and other conditions were injected into hundreds of thousands of babies.

The government confiscated the Wuhan institutes illegal income, fined the company, and punished nine executives. But the company was allowed to continue to operate. It is now running a coronavirus vaccine project, and along with two other Chinese groups has been allowed to combine its safety and efficacy trials.

Several Chinese scientists questioned the decision, arguing that the vaccine should be shown to be safe before testing how well it works.

Nationalism Versus Globalism

In the early days of the crisis, Harvard was approached by the Chinese billionaire Hui Ka Yan. He arranged to give roughly $115 million to be split between Harvard Medical School and its affiliated hospitals and the Guangzhou Institute of Respiratory Diseases for a collaborative effort that would include developing coronavirus vaccines.

We are not racing against each other, we are racing the virus, said Dr. Dan Barouch, the director of the Center for Virology and Vaccine Research at Beth Israel Deaconess Medical Center and a professor at Harvard Medical School who is also working with Johnson & Johnson. What we need is a global vaccine because an outbreak in one part of the world puts the rest of the world at risk.

That all-for-one sentiment has become a mantra among many researchers, but it is hardly universally shared.

In India, the Serum Institute the heavyweight champion of vaccine manufacturing, producing 1.5 billion doses a year has signed agreements in recent weeks with the developers of four promising potential vaccines. But in an interview with Reuters, Adar Poonawalla, the companys billionaire chief executive, made it clear that at least initially any vaccine the company produces would have to go to Indias 1.3 billion people.

The tension between those who believe a vaccine should go where it is needed most and those dealing with pressures to supply their own country first is one of the defining features of the global response.

The Trump administration, which in March put out feelers to a German biotech company to acquire its vaccine research or move it to American shores, has awarded grants of nearly half a billion dollars each to two U.S.-based companies, Johnson & Johnson and Moderna.

Johnson & Johnson, though based in New Jersey, conducts its research in the Netherlands.

Paul Stoffels, the companys vice chairman and chief scientific officer, said in an interview that the Department of Health and Human Services understood we cant pick up our research and move it to the United States. But it made sure that the company joined a partnership with Emergent BioSolutions a Maryland biological production firm to produce the first big batches of any approved vaccine for the United States.

The political reality is that it would be very, very hard for any government to allow a vaccine made in their own country to be exported while there was a major problem at home, said Sandy Douglas, a researcher at the University of Oxford. The only solution is to make a hell of a lot of vaccine in a lot of different places.

The Oxford vaccine team has already begun scaling up plans for manufacturing by half a dozen companies across the world, including China and India, plus two British manufacturers and the British-based multinational AstraZeneca.

In China, the governments instinct is to showcase the countrys growth into a technological power capable of beating the United States. There are nine Chinese Covid-19 vaccines in development, involving 1,000 scientists and the Chinese military.

Chinas Center for Disease Control and Prevention predicted that one of the vaccines could be in emergency use by September, meaning that in the midst of the presidential election in the United States, Mr. Trump might see television footage of Chinese citizens lining up for injections.

Its a scenario we have thought about, one member of Mr. Trumps coronavirus task force said. No one wants to be around that day.

Traditional Versus New Methods

The more than 90 different vaccines under development work in radically different ways. Some are based on designs used for generations. Others use genetic-based strategies that are so new they have yet to lead to an approved vaccine.

I think in this case its very wise to have different platforms being tried out, Dr. De Wilde said.

The traditional approach is to make vaccines from viruses.

When our bodies encounter a new virus, they start learning how to make effective antibodies against it. But they are in a race against the virus as it multiplies. Sometimes they produce effective antibodies quickly enough to wipe out an infection. But sometimes the virus wins.

Vaccines give the immune system a head start. They teach it to make antibodies in advance of an infection.

The first vaccines, against diseases like rabies, were made from viruses. Scientists weakened the viruses so that they could no longer make people sick.

A number of groups are weakening the coronavirus to produce a vaccine against Covid-19. In April, the Chinese company Sinovac announced that their inactivated vaccine protected monkeys.

Another approach is based on the fact that our immune system makes antibodies that lock precisely onto viruses. As scientists came to understand this, it occurred to them that they didnt have to inject a whole virus into someone to trigger immunity. All they needed was to deliver the fragment of a viral protein that was the precise target.

Today these so-called subunit viral vaccines are used against hepatitis B and shingles. Many Covid-19 subunit vaccines are now in testing.

In the 1990s, researchers began working on vaccines that enlisted our own cells to help train the immune system. The foundation of these vaccines is typically a virus called an adenovirus. The adenovirus can infect our cells, but is altered so that it doesnt make us sick.

Scientists can add a gene to the adenovirus from the virus they want to fight, creating whats known as a viral vector. Some viral vectors then invade our cells, stimulating the immune system to make antibodies.

Researchers at the University of Oxford and the Chinese company CanSino Biologics have created a viral vector vaccine for Covid-19, and theyve started safety trials on volunteers. Others including Johnson & Johnson are going to launch trials of their own in the coming months.

Some groups, including the American company Inovio Pharmaceuticals, are taking a totally different approach. Instead of injecting viruses or protein fragments, theyre injecting pure DNA, which is read by the cells machinery, making a copy as an RNA molecule. The RNA is then read by the cells protein-building factories, making a viral protein. The protein in turn comes out of the cell, where immune cells bump into it and make an antibody to it.

Other teams are creating RNA molecules rather than DNA. Moderna and a group at Imperial College London have launched safety trials for RNA vaccines. While experimental, these genetic vaccines can be quickly designed and tested.

It is one thing to design a vaccine in record time. It is an entirely different challenge to manufacture and distribute one on a scale never before attempted billions of doses, specially packaged and transported at below-zero temperatures, to nearly every corner of the world.

If you want to give a vaccine to a billion people, it better be very safe and very effective, said Dr. Stoffels of Johnson & Johnson. But you also need to know how to make it in amounts weve never really seen before.

So the race is on to get ahead of the enormous logistical issues, from basic manufacturing capacity to the shortages of medical glass and stoppers that Mr. Gates and others have warned of.

Researchers at Johnson & Johnson are trying to make a five-dose vial to save precious glass, which might work if a smaller dose is enough for inoculation.

Each potential vaccine will require its own customized production process in special clean facilities for drug making. Building from scratch might cost tens of millions of dollars per plant. Equipping one existing facility could easily cost from $5 million to $20 million. Ordering and installing the necessary equipment can take months.

Governments as well as organizations like the Gates Foundation and the nonprofit Coalition for Epidemic Preparedness Innovations are putting up money for production facilities well before any particular vaccine is proven effective.

Whats more, some vaccines including those being tested by the American companies Moderna and Inovio rely on technology that has never before yielded a drug that was licensed for use or mass-produced.

But even traditional processes face challenges.

Because of staff illnesses and social distancing, the pandemic this spring slashed productivity by 20 percent at the MilleporeSigma facility in Danvers, Mass., that supplies many drug makers with the equipment used for brewing vaccines.

Then, about three weeks ago, the first clinical trials for new proposed vaccines started. Urgent calls poured from customers around the world. Even before the first phase of the first trials, manufacturers were scrambling.

Demand went through the roof, and everybody wanted it yesterday, said Udit Batra, MilleporeSigmas chief executive, who has expanded production and asked other customers to accept delays to avoid becoming a bottleneck.

Treatments Versus Vaccines

Even as the world waits for a vaccine, a potential treatment for coronavirus is already here and more could be on the way.

Remdesivir showed modest success in a federally funded clinical trial, slowing the progression of the disease, but without significantly reducing fatality rates.

The F.D.A.s decision to allow its use comes as hundreds of other drugs mainly existing medicines that are being used for other conditions are being tested around the world to see if they hold promise. The F.D.A. said there are currently 72 therapies in trial.

Studies of drugs tend to move more quickly than vaccine trials. Vaccines are given to millions of people who are not yet ill, so they must be extremely safe. But in sicker people, that calculus changes, and side effects might be an acceptable risk.

As a result, clinical trials can be conducted with fewer people. And because drugs are tested in people who are already sick, results can be seen more quickly than in vaccine trials, where researchers must wait to see who gets infected.

Public health experts have cautioned there will likely be no magic pill. Rather, they are hoping for incremental advances that make Covid-19 less deadly.

Almost nothing is 100 percent, especially when you are dealing with a virus that really creates a lot of havoc in the body, said Dr. Luciana Borio, a former director of medical and biodefense preparedness for the National Security Council under President Trump.

Antiviral drugs like remdesivir battle the virus itself, slowing its replication in the body.

The malaria drug hydroxychloroquine which has been enthusiastically promoted by Mr. Trump and also received emergency authorization to be used in coronavirus patients showed early promise in the laboratory. However, small, limited studies in humans have so far been disappointing.

Many in the medical community are closely watching the development of antibody drugs that could act to neutralize the virus, either once someone is already sick or as a way of blocking the infection in the first place.

Dr. Scott Gottlieb, a former F.D.A. commissioner, and others said that by the fall, the treatment picture for Covid-19 could look more hopeful.

If proven effective in further trials, remdesivir may become more widely used. One or two antibody treatments may also become available, providing limited protection to health care workers.

Even without a vaccine, Dr. Borio said, a handful of early treatments could make a difference. If you can protect people that are vulnerable and you can treat people that come down with the disease effectively, she said, then I think it will change the trajectory of this pandemic.

David E. Sanger reported from Washington, David D. Kirkpatrick from London, Carl Zimmer and Katie Thomas from New York and Sui-Lee Wee from Singapore. Denise Grady and Maggie Haberman contributed reporting.

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Profits and Pride at Stake, the Race for a Vaccine Intensifies - The New York Times

BEST AND BRIGHTEST: Pre-med track student has high expectations – Colorado Springs Gazette

This is the 17th of a series of 20 profiles of The Gazettes Best and Brightest Class of 2020.

Like most high school seniors, the COVID-19 pandemic has directly impacted Katie Morales.

While she wishes she could be walking the halls of St. Marys with her friends as she ends her successful high school career, Morales said the pandemic has opened her eyes to more possibilities and interests in her future as she prepares to begin her journey as a pre-med student at the University of Notre Dame.

Ive never experienced anything like this before, and its the biggest event in my lifetime. Its definitely kind of scary looking forward but Im also interested in maybe what I can do in the future, Morales said. A couple months ago me and my friends were like, We dont want to go to school, but now for the first time we wish we were at school. It showed me that everyone is going through difficulties, and I think this situation has made me more grateful for what I have and the opportunities.

While the most recent pandemic has sparked some interest, her heart has been set one working with children and pediatric medicine since she began volunteering in the pediatric wing of Memorial Hospital.

It meant a lot to me to feel like Im making a difference, she said. I love seeing the children play and I love making them laugh. Even with their circumstances, Ive never seen a kid that looked very sad. They are so strong and happy and are able to just enjoy the moment.

Ive learned that I dont want to take anything for granted, and (the kids) have taught me to find the beauty in everything and enjoy life even when its hard.

At Notre Dame, Morales plans to major in biomedical engineering with a minor in computer science, with hopes of earning a pediatric residency to specialize in oncology and hematology. But her per-med track wasnt always her plan. Morales originally thought engineering would be her future, but seeing her older brother, Joe, go through medical school inspired her to forge the same pafirst hand the different opportunities available to her brother, especially when he spent time in hospitals throughout Colorado Springs.

Through her brothers experience, Morales is aware of the work and dedication required to successfully complete medical school. But thanks to her extracurriculars and advanced academic track at St. Marys, she has established a balancing act to remain focused and organized.

Morales said she struggled with anxiety through high school, which peaked her sophomore year as she stretched herself too thin in an attempt to balance her activities and high expectations for herself.

I think what I found is the more things that I was involved in, it just made it harder for me to feel fully committed. When I was doing one thing I was worrying about the next thing, and I wanted everything to go perfectly. I was never really enjoying the moments I was in, she said.

But a conversation with her high school priest opened her eyes to a new mindset to help her work through her anxiety without sacrificing activities.

He told her value lies in who she is as a person, as opposed to how successful she is.

That has been something thats really freeing for me. I opened up to him telling him the high standards I set for myself and how Im sometimes disappointed in myself. But he told me that God loves me and my family and friends love me for who I am rather than how successful I am, Morales said. I pushed myself harder and got up early to finish stuff. I think it will help me because I know what I will have to do to get work done and push myself through even though it seems hard at the time. When Im done, I know it will be worth it.

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BEST AND BRIGHTEST: Pre-med track student has high expectations - Colorado Springs Gazette

Ariadne Labs Partners with Harvard Medical School Students to Develop Evidence-Based Everyday Activity Guidelines for COVID-19 Protection – PRNewswire

BOSTON, April 30, 2020 /PRNewswire/ -- Ariadne Labs has partnered with the Harvard Medical School student group, HMS COVID-19 Student ResponseTeam, to develop and disseminate evidence-based, practical community guidance to help the general public protect themselves against COVID-19. In the midst of the overwhelming amount of information on COVID-19 currently circulating, this partnership aims to provide accurate, timely, and easily actionable guidance on a variety of everyday activities, ranging from safe grocery shopping to handling mail.

Consisting of more than 100 student volunteers from Harvard Medical School, the HMS COVID-19 Student Response Team was formed in March as a way to use their skills and resources to respond to the pandemic.

"The HMS COVID-19 Student Response Team represents the collaborative effort of hundreds of graduate student volunteers nationwide to address the need for up-to-date education and community activism during the COVID-19 pandemic," says Kruti Vora, a third year Harvard Medical School student who is co-leading the response team's Committee for Broader Education. "Everyday tasks like shopping for groceries, going for a walk, and picking up packages now have new risks, and we saw an opportunity to use our skills and networks to distill the flood of COVID-19 information and make the adjustment to a new normal safe, sustainable, and accessible to all members of our communities."

"As COVID-19 continues to spread, we've also seen a spread of misinformation. For many, it has become too difficult to differentiate between reliable information and potentially dangerous inaccuracies," noted Evan Benjamin, MD, Chief Medical Officer of Ariadne Labs and Associate Professor of Medicine at Harvard Medical School. "We are proud to collaborate with the Harvard Medical students to provide the general public with easy to use, evidence-based tools to empower everyone to take appropriate actions to stay healthy and slow the spread of the virus."

Today, the Safe Grocery Store Checklist was released to help ensure safety before, during, and after a trip to the grocery store. The checklist was developed as a result of background research, literature review, and consolidation of evidence into sets of recommendations that were tested through a rapid cycle feedback process. Sources include the Centers for Disease Control, Federal Drug Administration, the New England Journal of Medicine, the Journal of the American Medical Association, and other peer-reviewed publications. A review of recommendations in the mainstream media landscape was also completed to inform design and dissemination strategy.

Future checklists will include guidance on handling mail and packages, ordering takeout, and using masks.

"In just a short amount of time, our students have shown extraordinary leadership and have made significant contributions to the COVID-19response," said Ed Hundert, MD, Dean for Medical Education at Harvard Medical School. "It has been inspiring to see our next generation of leaders rise to the demands of this unprecedented time, and apply their expertise to make a positive impact."

To stay up to date the latest activities, visit https://covidstudentresponse.org/ and covid19.ariadnelabs.org.

About Ariadne Labs:

Ariadne Labs is a joint health systems innovation center at Brigham and Women's Hospital and the Harvard T.H. Chan School of Public Health. We develop simple, scalable solutions that dramatically improve the delivery of health care at critical moments to save lives and reduce suffering. Our vision is for health systems to deliver the best possible care for every patient, everywhere, every time. Visit ariadnelabs.org to learn more.

About the HMS COVID-19 Student Response Team:

The HMS COVID-19 Student Response Team was formed in early 2020 to identify ways that Harvard Medical School students could address the rapidly evolving needs presented by COVID-19. This student-led initiative aims to address four key areas: developing a COVID-19 curriculum for medical students, promoting public health messages through community education, liaising with Harvard Medical School administration and hospital leadership on best practices for re-engaging students in voluntary clinical roles, and supporting frontline healthcare workers and vulnerable communities with non-clinical services. Visit https://covidstudentresponse.org/ to learn more and follow@FutureMDvsCOVID on social media.

Contact: Brigid Tsai, [emailprotected]

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Ariadne Labs Partners with Harvard Medical School Students to Develop Evidence-Based Everyday Activity Guidelines for COVID-19 Protection - PRNewswire

This Austinite Voted Dell Med into ExistenceNow She’s One of the School’s First Graduates – The Alcalde

BySofia Sokolove in 40 Acres, May | June 2020 on May 1, 2020 at 12:51 pm |

Eight years ago, Travis County residents had a decision to make: did they want a medical school badly enough they were willing to pay higher property taxes to fund it? Brooke Wagner did. An East Austin resident since 2007, Wagner was an ardent supporter of Central Health Proposition 1the 2012 tax increase that, if approved, would generate the final chunk of revenue needed to give the city an improved health care system based around a teaching hospital. Please vote for Prop 1, she asked family, friends, neighbors, and anyone else who would listen. We need a medical school here. And I want to go there.

That last part was more of a daydream. Wagner hadnt been in a classroom in nearly two decades, and the youngest of her three children, her daughter, Elaia, was barely two years old. It was just one of those things you say, Wagner says when we meet for coffee in February. Kind of like, I want to be in the Super Bowl.

But sometimes we speak things into existence. On Nov. 6, 2012, in a historic move, 54 percent of Austin residents agreed with Wagner, voting to raise their own taxes for a medical school. This summer, Dell Med will graduate its inaugural class and Wagner, 43, will be one of 49 new Longhorn MDs.

Wagner grew up in Albuquerque, New Mexico, before heading off at 18 to Wofford College, a tiny liberal arts school in South Carolina. While double majoring in biology and Spanish, she realized she wasnt so sure about pursuing medicine. As we go through school, she says, we keep becoming the people that were going to be. Undergrad made Wagner want to know herself better, and that felt like a challenge within the confines of academia. She was exhausted by grades, and tired of performing for other people. Also, she was in love. The summer before her senior year, Wagner married her high school sweetheart, Taylor.

By 21 and 19, respectively, Brooke and Taylor had their first son, Corin. A year later, they moved to Austin for Taylors job at a tech startup. They had a second son, Ari, in 2002. When she found Corin reading Civil War history books at the age of four, she decided to home-school her kids.

That began the next 20 years of what she calls her weird path of doing very alternativethings. She taught herself how to build houses and bought houses to flip. She built a shipping container pool. When she moved to East Austin, she put her Spanish to use as an advocate for her non-English speaking neighbors, placing and translating calls to hospitals and insurance companies on their behalf, and volunteered as a medical interpreter in an official capacity on mission trips to Guatemala and Mexico. In 2011, she and Taylor followed through on a promise they made to each other on one of their first dates and adopted a child, taking the boys on a week-long trip to Ethiopia to pick up their new sister Elaia.

Throughout it all, though, Wagner says she kept her childhood dream of becoming a physician. After a moment of clarity on a 2014 trip with her mother and Elaia to Connecticut, she called Taylor and told him she was thinking about applying to Dell Med. Well, yeah, he responded.

Wagner used to think it was her attention to detail that would make her a great doctor. Now she thinks about medicine differently. I guess you check some boxes, she says, but really youre dealing with people, and people are infinitely interesting. The challenges that they face are infinitely variable, and the privilege of being allowed into someones world as a physician is incredible. There isnt a box to check on that.

It is a perspective she wouldnt have come to without years of real-world experience. And it is one that aligns with Dell Med, whose overarching mission since its conception has been about rethinking and transforming health care to be more holistic, with a unique focus on its surrounding community.

Wagner still remembers the gigantic syllabi and textbooks friends in other medical schools would lug around, trying to commit all of it to memory. In her four years at Dell Med, Wagner and her classmates have never been handed a textbook. Instead, she says, they are sent off to do their own research on the topics they are learning, devouring journals and news articles, and gathering real-world experience. They delve into the human side before exploring how economic realities might influence whatever condition it is they are studying, then explore sociological circumstances, and so on.

On the day we meet, Wagner comes straight from the Travis County Courthouse. She has spent a lot of time there lately, in addition to time at crisis respite centers and the Travis County and Williamson County jails. Wagner is taking the month to learn everything she can about integral carethe mental health component to community careto gain a big picture idea of the circumstances her future patients might be coming from, or where she can send them if they need help. Her work can be deflating, but she remains optimistic. Everything Ive learned about the system just goes into the hopper of things I understand, she says. Into my toolbox.

On March 20, Match Day, Wagner matched to the only place she applied: the Internal Medicine residency at Dell Med. She will spend the next three years working in the hospital and at the VA as an internist under the supervision of the internal medicine faculty, and hopes to use the research component of her residency to work on innovating at-home care for veterans served at the VA. And when shes finished? Id love to walk out my door and practice medicine in East Austin, she says. For the last two years, Wagners mentor has been Travis Countys Medical Societys 2019 Physician of the Year Guadalupe Zamora, whose practice is five blocks from Wagners house. Her dream is to have her own practice like Zamora.

She wants to co-manage health with patients, instead of prescribing them what she thinks they need without asking plenty of questions. She wants patients to have her cell phone number, and to feel comfortable calling her to ask if they need to go to the emergency room. She vows to keep going to her usual H-E-B, even if her patients stop her in the aisles to ask questions. I think its OK for my life to bleed all together, she says. Im not saying I want to work all the time. But Im going to be a human who is a doctor. Not a doctor for a group of people I would never see in any other context.

Above all, Wagner just wants to be a great physician. She doesnt want her patients to think of her as being smart in a vacuumshe wants them to think she can do a good job taking care of them. People need a partner in their doctor, Wagner says. One of my main jobs is to say, You can be stressed, and were going to work on this together.

Photograph by Summer Miles

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This Austinite Voted Dell Med into ExistenceNow She's One of the School's First Graduates - The Alcalde

Fresh out of med school, grads move to the pandemic front lines – Newsday

Newsday is opening this story to all readers so Long Islanders have access to important information about the coronavirus outbreak. All readers can learn the latest news at newsday.com/LiveUpdates.Your subscription is important because it supports our work covering the coronavirus outbreak and other strong local journalism Newsday provides. You can find the latest news on the coronavirus outbreak at newsday.com/LiveUpdates.

Two new Long Island doctors thought they would be taking time off and travelingafter graduating from medical school this spring.

Alison Laxer, 27, and Alexander Smith, 25, instead put on their scrubs and white coats to join the front lines of the coronavirus pandemic.

Its unlike anything they would have imagined, the couple said.

In their first two weeks on the job at North Shore University Hospital in Manhasset, Laxer and Smith witnessed scenes far different fromwhat they had grown accustomed to during rotations.

Some patientswere too sick to consent to clinical trials.Glass walls protected workersfrom patients, andentire units were transformed to house the intubated. There was also the task of putting on various pieces of personal protective equipment.

Its very surreal, introducing yourself as 'doctor' for the first time in this environment, said Laxer, who lives with her boyfriend Smith in Great Neck.

They officially became doctors onApril 10, a month earlier than their scheduled graduation date from the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.

Gov. Andrew M. Cuomo gave the directive earlier this month to speed up the graduation of fourth-year med school studentsso that they can join the workforce. The Class of 2020 at the school of medicine at Hofstra will still have a virtual graduation ceremony on May 11.

Laxer and Smith are two of more than 40 graduates who joined the Graduate Coronavirus Task Force deployed throughout Northwell Health hospitals to combat thepandemic.

As the daughter of two doctors an internist and endocrinologist who met as residents in the hospital she works at now Laxer had been excitedly waiting for her graduation day.She envisioned walking across the stage and her parents waiting on the other end to hood her.

"Thats the moment you become a doctor, she said. But I felt like we never had a 'moment.'

Unceremoniously,three days after becoming doctors and getting trained via Zoom chats, they entered the hospital with their new assignments.

Laxer, who plans to do her residency in pediatrics, was assigned to work as a consenting physician, informing patients or their families of recommended clinical treatments. She has mixed feelings about treating patients in serious condition just days out of med school.

I would want the most experienced person, so sometimes I feel bad," Laxer said. "But then I remember putting on the news and itching to do something to help.

Meanwhile, Smith has been working in the intensive care unit with patients who need breathing tubes. He intends to do his residency in internal medicine. He saidnavigating the uncertainty with coronavirus treatment has been unlike anything he's trained for.

"If I had a patient with a heart attack, its unlikely to change between now and a month from now how we as a team would treat that patient," Smith said.

But with COVID-19 patients, it's crucial to communicate the uncertainties with the families of patients.

It's "different than anything I wouldve expected in my first experience out of having graduated from medical school," he said.

Still, Smith and Laxer said they can't imagine sitting back during this crisis.

"I feel like this is like the first time that were going through something as a country and I can actually help," Laxer said. "Itsvery empowering to feel like you actually can lend a hand and do something."

Smith saidthere was no question that he would answer the call to join the ranks of physicians on the front line of thepandemic.

"I think that regardless of how we had envisioned our fourth year, it was just a no-brainer," Smith said. "The answer was yes."

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Fresh out of med school, grads move to the pandemic front lines - Newsday

Medical students need to learn about health disparities to combat future pandemics – AAMCNews

Editors note: The opinions expressed by the author do not necessarily reflect the views of the AAMC or its members.

One of the most alarming consequences of the coronavirus pandemic in the United States is that disproportionately high rates of chronic diseases like hypertension, asthma, and diabetes among people of color are dramatically affecting outcomes and mortality from COVID-19.

In my state of Alabama, over 45% of the states 197 COVID-19 deaths are among African Americans, while the states population is just 26% African American.

Similar trends are emerging across the country. In Michigan, African Americans account for 40% of COVID-19 deaths, despite representing only 14% of the states population. In Louisiana, African Americans represent 70% of deaths while accounting for just 33% of the states population. And in Illinois, African Americans make up over 40% of COVID-19 deaths but just 14% of the population.

Other minority populations have likewise been heavily impacted. In Washington state, 28% of those infected are Hispanic, even though they make up just 13% of the states total population. In Utah, Hispanic or Latino people make up 14% of the states populationbut are 35% of COVID-19 cases. And as of April 20, the Navajo Nation had a per capita infection rate 10 times higher than that of neighboring Arizona and the third-highest infection rate in the country, according to NBC News.

Racial and socioeconomic health disparities among communities of color are driven in large part by unequal access to primary care, housing, education, transportation, and healthy foods. In fact, research has shown that socioeconomic and environmental factors account for approximately 50% of a persons overall health.

Even under normal circumstances, our failure to address health disparities comes at a steep price. According to the Kaiser Family Foundation, disparities amount to approximately $93 billion in excess medical care costs and $42 billion per year in lost productivity and premature deaths.

The coronavirus pandemic has illustrated, perhaps more vividly and starkly than any event in our lifetimes, the critical importance of addressing these health disparities. Certainly no one can reasonably expect physicians to solve societal problems like poverty and racism. However, continuing to equip medical students with an understanding of cultural competence, help them recognize and address racial bias in medicine, and teach them about the costs of health disparities both as they affect patient outcomes and the health care system at large is vital to improving care and reducing costs in the long run.

In light of the coronavirus pandemic, disaster preparedness and public health are likely to become a greater focus of many medical schools curriculum. However, health disparities will remain one of the most critical issues affecting patient outcomes and health care costs, not just in an emergency but persistently. Moreover, minorities and socioeconomically disadvantaged populations are likely to suffer the most in any future epidemic or pandemic, just as they are now.

This is not an either/or scenario in a post-coronavirus pandemic world, medical schools should strive to better integrate both social determinants of health/health disparities and public health/disaster preparedness in the training of health care providers. Addressing health disparities and social determinants of health, in part through providing culturally competent care, will not only make us a healthier country but will also make all our communities better prepared to confront and survive the next pandemic.

Selwyn Vickers, MD, is senior vice president of medicine and dean of the University of Alabama School of Medicine. Other contributors include: L.D. Britt, MD, MPH, chair of the Department of Surgery at Eastern Virginia Medical School and past president of the American College of Surgeons; Deborah Deas, MD, MPH, vice chancellor for health sciences and the Pam and Mark Rubin dean at the University of California, Riverside, School of Medicine; Henri Ford, MD, dean of the University of Miami Leonard M. Miller School of Medicine; James Hildreth, MD, PhD, president and CEO of Meharry Medical College; Danny Jacobs, MD, MPH, president of Oregon Health & Science University; Robert Johnson, MD, dean of Rutgers New Jersey Medical School and interim dean of Rutgers Robert Wood Johnson Medical School; Talmadge King Jr., MD, dean of the University of California, San Francisco, School of Medicine; Ted Love, MD, president and CEO of Global Blood Therapeutics; Charles Mouton, MD, executive vice president, provost, and dean of the University of Texas Medical Branch School of Medicine; E. Albert Reece, MD, PhD, MBA, executive vice president for medical affairs at the University of Maryland, Baltimore, and dean of the University of Maryland School of Medicine; Valerie Montgomery Rice, MD, president and dean of the Morehouse School of Medicine; Joseph Tyndall, MD, MPH, professor and interim dean of the University of Florida College of Medicine; and David Wilkes, MD, dean of the University of Virginia School of Medicine.

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Medical students need to learn about health disparities to combat future pandemics - AAMCNews

UND med school, Altru partner to provide testing solution for COVID-19 – Grand Forks Herald

Marijo Roiko, microbiology program director in Altrus pathology and laboratory services department, and the medical schools Catherine Brissette and Matthew Nilles, associate professors in the biomedical sciences department, have produced a solution to help aid in COVID-19 testing. The solution, known as a viral transport medium, is used to maintain the stability of a clinical specimen from the point of collection to laboratory testing.

After a swab test is administered the swab can be placed in the solution to ensure that the test can be transported or stored long-term, according to Nilles. The liquid medium is also used for other types of clinical testing.

The COVID-19 testing shortfalls the country has experienced go beyond not having enough physical tests, Brissette said. Its also about not having enough swabs or transport solution. The UND-Altru team has produced enough of the solution for more than 1,600 COVID-19 tests.

Across the country, VTM has been in short supply since the COVID-19 outbreak began, Nilles said. However, this partnership between lab scientists at Altru and UND is helping alleviate the shortage in a significant way.

The locally produced solution was developed from reagents available in laboratories at the two institutions. The compound was vetted by quality assurance testing at Altru and the North Dakota Public Health Laboratory.

This medium has supported more than 90% of COVID-19 tests conducted in the Altru service area since April 1, Roiko said in a statement. This has allowed local health care agencies to maintain a steady pace of testing, and additional production of the medium can be ramped up, as needed.

Nilles said the team will continue to produce the transport solution, but likely at a lowered rate as the commercially made solution is becoming more available again.

I think it's going to slow down a little bit, but I think there's a good chance we'll continue with it for a while, he said.

Though health care providers still need to manage shortages of items, including nasal swabs, they are now much less concerned about running out of the transport solution, according to Roiko.

Altru is very grateful for the partnership," she said.

Brissette said the team has been practicing social distancing while working in the lab with each person doing a part in the process, but shes found the experience to be enjoyable.

It's been fun, she said. I think both Matt and I are really happy to be actually doing something that's helping out in this situation. You feel so helpless in a pandemic sometimes, so it's nice that we're able to use our skills and contribute something.

Working together to solve problems, such as these, is an important part of getting through this pandemic, Brissette said.

While lab scientists arent necessarily on the front line of this fight, theyre crucial to helping our nation get through this, Brissette said. And the more institutions can partner on solutions like this, so much the better it will save time, money and, hopefully, lives.

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UND med school, Altru partner to provide testing solution for COVID-19 - Grand Forks Herald

UMass Medical School cell biologist Thoru Pederson elected to American Academy of Arts & Sciences – Worcester Telegram

Craig S. Semon Telegram & Gazette Staff @CraigSemon

WednesdayApr29,2020at11:10AMApr29,2020at6:49PM

WORCESTER UMass Medical School cell biologist Thoru Pederson has been elected to this year's class of the American Academy of Arts and Sciences.

It is a great honor to be recognized by one's guild in my case the profession of cell biology, Pederson said. But that this venerable institution is one of both the arts and the sciences adds so much to my sense of profound privilege in having been elected.

Pederson is the Vitold Arnett professor of cell biology, associate vice chancellor for research and professor of biochemistryand molecular pharmacology at UMass.

A longtime scientist at the Worcester Foundation for Biomedical Sciences, Pederson served as the foundations president from 1985 until its merger withUMass in 1997.

Pedersons election to the academy recognizes his career of research on the functional organization of the cell nucleus, including specific associations between RNAs and proteins to form machines that underlie gene readout. He has also made transformative discoveries about the nucleolus.

Most recently Pederson and collaborators have designed CRISPR-based methods to probe the fine-scale movements of specific genomic loci.

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UMass Medical School cell biologist Thoru Pederson elected to American Academy of Arts & Sciences - Worcester Telegram

Best Medical Schools In The World For 2020 – CEOWORLD magazine

Johns Hopkins University School of Medicine takes the prestigious title of the worlds medical school for 2020, thats according to the CEOWORLD magazine. Medical Sciences Division at the University of Oxford earned itself a respectable second place, with karolinska institutet is ranked third.

The 2020 rankings placed Harvard Medical School in fourth ahead of David Geffen School of Medicine at UCLA (DGSOM) into fifth; while the University of Cambridge School of Clinical Medicine ranked sixth, and Stanford University School of Medicine seventh.

Overall, among the top 10 medical schools, the eighth, ninth, and tenth positions are held by UCL Medical School, Yale School of Medicine, and Faculty of Medicine at Imperial College London. UCSF School of Medicine took the No. 11 spot, followed by the University of Toronto Faculty of Medicine and Vagelos College of Physicians and Surgeons (VP&S) of Columbia University (No.13).

Meanwhile, All India Institute of Medical Sciences (AIIMS) ranked No. 14 in the CEOWORLD magazines ranking of the best medical schools in the world for 2020. Melbourne Medical School of The University of Melbourne came in fifteenth place, followed by London School of Hygiene & Tropical Medicine (sixteenth), Duke University School of Medicine (seventeenth), the University of Edinburgh Medical School (eighteenth), and Perelman School of Medicine of the University of Pennsylvania, ranked nineteenth.

Out of 77 best medical schools in the world for 2020, the University of Yong Loo Lin School of Medicine of the National University of Singapore ranked No. 20th. Only fully accredited degree programs or schools in good standing during the study period are ranked.

So, if you are thinking about boosting your prospects with an accredited degree in medicine, we have got just the thing for you; here are 77 outstanding international medical schools that can help advance your career

Methodology: CEOWORLD magazines best medical schools in the world for 2020 is based on 7 major indicators of quality, overall Score (100%) is the sum of:

1) Academic reputation2) Admission Eligibility3) Specialization4) Global reputation and influence5) Annual tuition and fees6) Research performance7) Student satisfaction

We believe rankings are one useful tool among many for evaluating the merits of a school of degree program, but should not be relied upon exclusively or take the place of personal judgment or consultation with educational experts. Data for these indicators were collected from publicly available sources, medical schools website, as well as our own editorial judgement. Information considered includes rankings and awards from reputable national and international publications, student-to-professor ratio, admissions acceptance rate, retention and graduation rates, tuition cost, financial aid availability, and accreditation. Students, industry professionals, and academicians were asked to rate medical schools on a scale of 1 marginal to 100 outstanding or dont know.

*However, this is by no means a comprehensive list, while the 77 medical schools above are the CEOWORLD magazines best medical schools in the world for 2020, there may be many other outstanding schools that offer excellent programs.* This rankings should not be viewed as the most important aspect when choosing a medical school, and are simply one element to consider.* Some of the institutions featured in this article are commercial partners of the CEOWORLD magazine.* The top-ranked medical school receives 100 points.* The rankings are the result of a rigorous analytical exercise, incorporating multiple data sources, without relying on university data submissions.* Detailed survey data and information collected directly from 90,000 individuals, across 7 data points.* Surveys completed by 40,000 students, 48,000 industry professionals, and 2,000 academicians around the world.*The overall score is numerical scores given to the schools based on students, academicians, and industry professionals measuring the quality of the school. Overall scores are out of 100.

The margin of sampling error for the full sample of 90,000 respondents is plus or minus 1.2 percentage points. In addition to sampling error, one should bear in mind that as in all survey research, there are possible sources of errorsuch as coverage, nonresponse and measurement errorthat could affect the results.

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William Carey gets creative to keep medical students learning – HubcitySPOKES.com

Students at the William Carey University College of Osteopathic Medicine, headquartered in Hattiesburg, are continuing to receive their education but in modified, nontraditional formats.

Due to the COVID-19 pandemic, following national guidelines, the medical college has moved its entire educational curriculum online for all students, regardless of where they are at in the four-year program, according to Dr. Italo Subbarao, dean.

At this time, the campus is closed, and students are taking all courses online, said Subbarao.

The transition to online learning has itself been a learning experience for first-year medical students Lindsay Knight Batista of Hattiesburg and Chase Boehmer of Grants Pass, Oregon.

Batista, 24, hopes to match into a pediatrics residency when she completes her education in 2023.

She said the transition to online education was challenging but not terrible.

We have livestreamed lectures as well as voiceover PowerPoints that we can watch from home, so we still have that sense of normalcy that comes with hearing the voices of our professors, she said.

First-year students have two main clinical classes, according to Knight, including Osteopathic Principles and Practice and Clinical Patient Care. Those classes usually have lab components.

(They) no longer have their true lab counterparts, she said. For Osteopathic Principles and Practice, we engage in a weekly one-hour small group meeting to talk over the material. As for (Clinical Patient Care), there is unfortunately not much that we can do aside from practicing on those we have around us.

Boehmer, 30, is interested in emergency medicine, trauma surgery, general surgery, asthma and allergy treatment, and clinical research. Prior to medical school, he worked for five years as a certified clinical research coordinator specializing in respiratory clinical trials.

While the (transition to online classes) has been manageable for most classes, others ... cannot be as easily substituted by an online format, he said. In these classes, the high degree of physical contact is a core component of the educational experience. This also applies to classes with a laboratory component.

Boehmer added that most medical students learn best in hands-on environments.

Online classes just dont have that aspect despite the best efforts of our professors, he said. Having all of our classes moved online is definitely making it more challenging to learn some of the material. For example, it poses a challenge to learn the highly advanced anatomic architecture of the human brain without being able to observe and touch these features on a real specimen.

Knight said she doesnt believe anything can replace an in-person clinical lab.

We rely heavily on those labs to make us knowledgeable and well-practiced future doctors, she said. Without being able to practice our clinical skills regularly, we run the risk of losing some of our fine-detail skills.

Despite the challenges, the two students and their counterparts are making the most of the situation.

As most people know, medical school is extremely challenging, so its best to find what works for your learning style early on and stick to it, said Boehmer. I will say that being forced to adopt a new learning style is a great practice for future encounters as physicians when we are faced with the unpredictable nature of the real world.

Knight said she tries to stay on schedule, practice her clinical skills and continue to study with a group of friends.

Being able to virtually study with my friends makes a huge difference. Knowing that we are all in this together, as well as just seeing their faces through a video chat, really helps to keep me motivated to work hard from home, she said.

Typically, medical students spend the first two years of their four-year education in the classroom and in lab experiences. The final two years of their education are spent in clinical rotations, which are hands-on learning opportunities in hospitals and clinics around the state.

Those opportunities look a lot different in the age of COVID-19, said Subbarao. The dean said those clinical experiences have been paused because of the concerns regarding infectious disease risk, insufficient (personal protective equipment) and still-developing clinical protocols.

The school is adapting its curriculum to fit the situation, he said, and medical school officials are focusing on telemedicine or the practice of caring for patients remotely and public health education.

We are using best practices for online clinical education, said Subbarao. That includes additional education on telemedicine and hosting simulated telemedical encounters with our standardized patients through a video platform. That also includes completing assignments and course modules on public health, COVID and other relevant subjects.

Subbarao said he hopes students can resume clinical rotations in the summer. He added that several medical students from William Carey are currently active in the fight against COVID-19.

Working with the Mississippi State Department of Health, we have allowed some students to support the COVID-19 (phone) hotlines in Jackson and to support contact tracing at other hospital systems in the state, he said.

Some states, including New York, are allowing fourth-year medical students to graduate early and join the ranks of doctors fighting the virus. Subbarao said the schools accreditation agency has allowed for early graduation if needed.

Thankfully, our case counts (in Mississippi) are not the same as in New York ... and so our state has not demanded that of us, he said. Our graduation is set for May 23 ... and our hope is that, if we continue to follow our local and state guidance, early graduation will not be required.

Subbarao said the virus will likely cause delays or adjustments to several other activities at the medical school, including national board exams in the summer and possibly even the start to the new academic year.

We are planning to be flexible as we proceed into our next academic year ... and that means we will be prepared to start online if that is required, he said. We are very fortunate that our recruitment has been minimally impacted for our next academic year. That process itself changed in mid-March when we started to do virtual interviews with our candidates.

The dean said he was very proud of efforts made by students and faculty members to adapt to the challenges brought by COVID-19.

They have been true professionals during this challenging time, he said. Working together, we have adapted, made tweaks ... and I feel pretty good about our delivery and assessment of our educational efforts.

Subbarao said William Carey medical school graduates are contributing to the COVID-19 fight across the country, and he is also proud of those efforts.

We already have over 600 graduates ... and 35 or so who practice in the Pine Belt area, he said. We have Carey grads who are in the New York City area, New Orleans ... and other hot spot areas around the country. They are providing exceptional care during this challenging time.

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Fenves and Johnston: Kirk Watson Transformed Health and Health Care in Austin – The Alcalde

ByGregory L. Fenves and Clay Johnston in 40 Acres on April 30, 2020 at 11:28 am |

Dear Senator Watson,

In your final week as a Texas state senator, we have been reflecting on the extraordinary impact you have had on our community and your special legacy in shaping the health care mission of The University of Texas at Austin.

In the early 2000s, there was much talk of building a medical school in Austin. It was an ambition that had been discussed for decades but had never materialized. A medical school in one of the largest cities without one felt like an idea that would be perpetually pushed to the future for a later generation to take on.

But in 2011, you changed everything. Your 10 Goals in 10 Years for Health Care lit the fire. Immediately, the pathway forward for our city and county was illuminated.

The No. 1 goal on your 10 in 10 list was to build a medical school. This was your priority because you understood the tremendous talent and resources available at our university. You knew that UT Austin had the ability to build a medical school like no other and train generations of doctors who could serve our city, county, state and nation. So, you did what you do best brought people together to make it happen.

You made sure that a broad coalition worked collaboratively on a shared vision for health in Texas. You helped people see health care as a fundamental issue that affects everyone regardless of background, beliefs or politics. And you made your case for change by telling your personal story as a cancer survivor, and people responded. Nobody else could have done that.

It all came together in 2012, when Travis County voters in an unprecedented move approved a ballot measure to invest in the creation of a new medical school. That commitment launched the Dell Medical School. And with strong support from the UT System Board of Regents, the Michael & Susan Dell Foundation and so many others in our Longhorn community, Dell Med welcomed its first class of 50 students in 2016.

And here we are now, nearly four years later, with Dell Meds inaugural class preparing to graduate next month.

Senator Watson, you made it possible for Dell Meds nearly 200 students to receive a world-class medical education right here in our states capital. And now, the first graduates are going to pay it forward all have matched with residency programs across the country and almost half of them will remain in Texas (11 will stay right here in Austin) to practice medicine and serve at a time when they are needed to help lead us through an unprecedented public health crisis.

And your impact on the universitys health care mission goes beyond our students and future doctors: UT Health Austins medical workers have been on the front lines of the COVID-19 crisis and are delivering patient-centered, value-focused care to our community; our unique partnerships with Central Health and Ascension Seton are further elevating the level of care in Austin; in 2014, the Livestrong Cancer Institutes emerged to pioneer new approaches to cancer treatment and care; in 2016, the Mulva Clinic for the Neurosciences took shape to advance patient treatment and neuroscience research; and just last year, your tireless work helped to prioritize the mental health needs of patients and families at the Austin State Hospital, which is now poised to become a premier center of brain health.

There is an old saying: Education is not the filling of a pail, but the lighting of a fire. You were the leader who lit the fire that sparked a health care revolution that started on our campus and is growing across Central Texas. Generations of Texans will benefit from all you have done.

You may be a University of Houston Cougar now, but forever in our community, you will be known as a Longhorn. Thank you, Senator Watson. We are deeply grateful.

Gregory L. Fenves is President of The University of Texas at Austin.

S. Claiborne Clay Johnston is dean of the Dell Medical School at The University of Texas at Austin.

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Fenves and Johnston: Kirk Watson Transformed Health and Health Care in Austin - The Alcalde

AAMC recognizes Tulane medical student whose perseverance inspired a nation – News from Tulane

Russell Ledet, PhD, a Tulane School of Medicine student, received a Herbert W. Nickens Medical Student Scholarship for his leadership in working to eliminate inequities in medical education. Ledets inspiring journey to become a doctor made national headlines this month. Above, he is pictured speaking at the School of Medicine's peaceful protest earlier in June. (Photo by Paula Burch-Celentano)

The AAMC (Association of American Medical Colleges) has awarded Tulane University medical student Russell Ledet, PhD, a Herbert W. Nickens Medical Student Scholarship for his leadership in working to eliminate inequities in medical education and health care.

The $5,000 scholarships are awarded annually to five outstanding third-year medical students who are leaders in addressing the educational, societal and healthcare needs of racial and ethnic minorities in the United States.

Through his own extraordinary example and through the work of the nonprofit he co-founded, Russell Ledet is inspiring more Black and other students of color to unapologetically pursue their dreams of becoming physicians, said Tulane University President Michael Fitts. Were so proud of him and his dedication to making the field of medicine more equitable, inclusive and more representative of the nation as a whole.

Russell Ledet is the personification of Tulanes values.

Dean Lee Hamm, MD

Russell Ledet is the personification of Tulanes values, said Dr. Lee Hamm, senior vice president and dean of Tulane University School of Medicine. His thoughtful approach to creating a constructive dialogue around the issues of healthcare inequity is an inspiration to those around him, and we are extremely proud he is a member of the Tulane community.

Ledet made headlines around the world last December when he organized a trip to Whitney Plantation in Louisiana for members of Tulanes Student National Medical Association. He and 14 other Black classmates posed for a series of pictures in front of the plantation, one of the few dedicated to telling the experiences of enslaved people in the South.

The powerful photos of 15 Black medical students standing proudly in their white coats where so many were denied a future quickly went viral. He and his classmates were featured inUSA Today,NPR,The Washington Post, CNN, Essence magazine, NBC News and more than 400 media outlets across the globe.

The students spurred a national conversation about Black excellence and the need for greater representation in medicine for people of color. African Americans make up 13 percent of the population in the United States, but account for only 5 percent of physicians and less than 7 percent of medical students, according to the AAMC.

The students formed a nonprofit called The 15 White Coats to get as many as 100,000 of the photos into K-12 schools across the country to inspire more young Black students to pursue their dreams in medicine. Ledet is president and manager of the nonprofit, which also raises money to help medical school applicants of color pay for the application process, which averages around $3,500 to $10,000 per student.

This month, Ledetmade national headlines again. On his first day of clinical training for surgery, he posted an emotional video from the parking lot of Baton Rouge General Medical Center. It was the same hospital where he worked years ago as a security guard who would ask doctors what it was like to be a physician. Many didnt notice him.

Even some of the people I used to work with who were security guards used to laugh at me when I would tell them, One day, I will be a doctor, he said in the video. When I was growing up, I didnt even know of a Black doctor I didnt know of any. So for this moment to come full circle is priceless.

Teen Vogue wrote about his unconventional path to medicine and People, Good Morning America, CNN, NBC Nightly News and more picked up his inspiring story of determination and perseverance.

Russell is the ideal recipient of the Herbert W. Nickens Medical Student Scholarship, said Bennetta Horne, director of the Office of Multicultural Affairs at Tulane University School of Medicine. His leadership efforts among his classmates here at Tulane School of Medicine, with his colleagues in the 15 White Coats organization, and in the community align perfectly with Dr. Nickens contributions to diversity and equity in medical education. His efforts will have a major effect on the reduction of health disparities and will show countless youth that medical education is a tangible opportunity for their futures.

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Study Finds That Children’s Immune Response Protects Against COVID-19 – PRNewswire

BRONX, N.Y., Sept. 21, 2020 /PRNewswire/ -- The first study comparing the immune responses of adults and children with COVID-19 has detected key differences that may contribute to understanding why children usually have milder disease than adults. The findings also have important implications for vaccines and drugs being developed to curb COVID-19. The study was published today in Science Translational Medicine and was conducted by scientists at Albert Einstein College of Medicine, Children's Hospital at Montefiore (CHAM), and Yale University.

The study involved 60 adult COVID-19 patients and 65 pediatric COVID-19 patients (less than 24 years old) hospitalized at CHAM and Montefiore Health System between March 13 and May 17, 2020; 20 of the pediatric patients had the novel multi-system inflammatory syndrome (MIS-C). The patients' blood was tested for the presence of several types of immune cells, antibody responses, and the inflammatory proteins, known as cytokines, that immune cells produce.

Children with COVID-19 fared significantly better than adults. Twenty-two adults (37%) required mechanical ventilation compared with only five (8%) of the pediatric patients. In addition, 17 adults (28%) died in the hospital compared with two (3%) of the pediatric patients. No deaths occurred among pediatric patients with MIS-C.

"Our findings suggest that children with COVID-19 do better than adults because their stronger innate immunity protects them against SARS-CoV-2, the novel coronavirus that causes the disease," said co-senior author Betsy Herold, M.D., chief of infectious diseases and vice chair for research in the department of pediatrics at Einstein and CHAM. Kevan C. Herold, M.D., C.N.H. Long Professor of Immunology and of Medicine at Yale School of Medicine, was the other co-senior author on the study.

People have two types of immunityinnate and adaptive. Innate immunity, in which immune cells respond rapidly to invading pathogens of all kinds, is more robust during childhood. Adaptive immunity, the second type of immune response, is more specific and features antibodies and immune cells that target specific viruses or other microbes.

Compared with adult patients, pediatric COVID-19 patients in the study possessed significantly higher levels of certain cytokines associated with the innate immune response. This suggests that young people's more robust innate response protects them from developing acute respiratory distress syndrome (ARDS)the hallmark of severe and often fatal COVID-19 cases. One cytokine in particular, known as IL-17A, was found at much higher levels in pediatric patients than in adults. "The high levels of IL-17A that we found in pediatric patients may be important in protecting them against progression of their COVID-19," said Dr. K. Herold.

Both pediatric and adult COVID-19 patients were found to make antibodies against the coronavirus' spike protein, which the virus uses to latch onto and infect cells. Those spike-protein antibodies include neutralizing antibodies, which block the coronavirus from infecting cells. Counterintuitively, the researchers found that neutralizing antibody levels in adult COVID-19 patients who died or required mechanical ventilation were higher than in those who recoveredand significantly higher than levels detected in pediatric patients.

"These results suggest that the more severe COVID-19 disease seen in adults is not caused by a failure of their adaptive immunity to mount T-cell or antibody responses," said Dr. K. Herold. "Rather, adult patients respond to coronavirus infection with an over-vigorous adaptive immune response that may promote the inflammation associated with ARDS."

The findings have important implications for COVID-19 therapies and vaccines. "Our adult COVID-19 patients who fared poorly had high levels of neutralizing antibodies, suggesting that convalescent plasmawhich is rich in neutralizing antibodiesmay not help adults who have already developed signs of ARDS," said Dr. B. Herold. "By contrast, therapies that boost innate immune responses early in the course of the disease may be especially beneficial."

As for vaccines, Dr. B. Herold notes that most vaccine candidates for protecting against SARS-CoV-2 infection are aimed at boosting neutralizing-antibody levels. "We may want to consider assessing vaccines that promote immunity in other ways, such as by bolstering the innate immune response," she said.

The paper is titled "Immune Responses to SARS-CoV-2 Infection in Hospitalized Pediatric and Adult Patients." Additional Einstein-Montefiore authors are: Carl A. Pierce, B.S., Clare Burn Aschner, Ph.D., Natalia Cheshenko, Ph.D., Benjamin Galen, M.D., Scott J. Garforth, Ph.D., Rohit K. Jangra, Ph.D., Erika Orner, Ph.D., Sharlene Sy, M.D, Kartik Chandran, Ph.D., and Steven C. Almo, Ph.D.; and Einstein Ph.D. students Natalia G. Herrera, B.S. and Nicholas C. Morano, B.S. Additional Yale authors are Aaron Ring, M.D., Ph.D., Paula Preston-Hurlburt, M.S. Yile Dai, Ph.D., and James Dziura, Ph.D.

About Albert Einstein College of MedicineAlbert Einstein College of Medicineis one of the nation's premier centers for research, medical education and clinical investigation. During the 2019-20 academic year, Einstein is home to 724 M.D.students, 158 Ph.D. students, 106 students in the combined M.D./Ph.D. program, and 265 postdoctoral research fellows. The College of Medicine has more than 1,800 full-time faculty members located on the main campus and at its clinical affiliates. In 2019, Einstein received more than $178 million in awards from the National Institutes of Health (NIH). This includes the funding of major research centersat Einstein in aging, intellectual development disorders, diabetes, cancer, clinical and translational research, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Its partnership with Montefiore, the University Hospital and academic medical center for Einstein, advances clinical and translational research to accelerate the pace at which new discoveries become the treatments and therapies that benefit patients. Einstein runs one of the largest residency and fellowship training programs in the medical and dental professions in the United States through Montefiore and an affiliation network involving hospitals and medical centers in the Bronx, Brooklyn and on Long Island. For more information, please visit http://www.einstein.yu.edu, read our blog, followus on Twitter, like us on Facebook,and view us on YouTube.

About Montefiore Health SystemMontefiore Health System is one of New York's premier academic health systems and is a recognized leader in providing exceptional quality and personalized, accountable care to approximately three million people in communities across the Bronx, Westchester and the Hudson Valley. It is comprised of 11 hospitals, including the Children's Hospital at Montefiore, Burke Rehabilitation Hospital and close to 200 outpatient care sites. The advanced clinical and translational research at its medical school, Albert Einstein College of Medicine, directly informs patient care and improves outcomes. From the Montefiore-Einstein Centers of Excellence in cancer, cardiology and vascular care, pediatrics, and transplantation, to its preeminent school-based health program, Montefiore is a fully integrated healthcare delivery system providing coordinated, comprehensive care to patients and their families. For more information please visit http://www.montefiore.org. Followus onTwitter and view us onFacebook andYouTube.

SOURCE Albert Einstein College of Medicine

http://www.einstein.yu.edu

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Michigan med school residents feel excitement, anxiety as they head to front lines in coronavirus fight – Detroit Free Press

The 2020 graduating class of medical students has been anticipating this season for years.

Tony Gjocaj, at the Michigan State College of Human Medicine, has been dreaming of Match Day ever since he was in middle school. Taylor Novice, who will be graduating from the University of Michigan Medical School and the Ross School of Business with her MD/MBA, cannot remember a time when she did not want to be a doctor.

Instead, a spring that traditionally brings recognition and celebration has become a time of stark uncertainty. On top of that, Gjocaj and Novice both have had to rescheduletheir respective May weddings.

Fourth-year medical students in Michigan were pulled from patient contact across the state in mid-March because of the coronavirus pandemic, marking an abrupt end to their final clinical rotations. Match Day banquets, scheduled for March 20 to honor the release of the National Resident Matching Program results, when students learn what hospital they will be placed in for their medical residency, were canceled and replaced with a day spent on FaceTime with loved ones. Graduation ceremonies planned for the coming months have shifted to be held virtually, if at all.

For students that matched with residency programs in-state, they have watched Michigan rise to be among the top 10in the nation for known coronavirus cases a pandemic hotspot, particularly in southeast Michigan.Incoming residents are grappling with an eagerness to join the front lines of COVID-19 care while experiencing some relief that they have a moment to prepare themselves before doing so. The excitement of altruism and commitment to service, lingering with an awareness of the risk and inevitable fear.

We sit in this limbo, explains fourth-year Wayne State School of Medicine student Andrew El-Alam, were overqualified students, but underqualified physicians.

Andrew El-Alam, medical student of Wayne State University poses for a photo in Detroit, Tuesday, April 21, 2020.(Photo: Junfu Han, Detroit Free Press)

In recent weeks, the Michigan Department of Licensing and Regulatory Affairs issued a directive allowing medical students who have successfully completed their academic requirements to secure an education license early. With the licensing option, graduates can enter the workforce ahead of the typical July 1 start date, helping to bring some relief to an already overworked army of health care workers fighting a medical war against an invisible and unforgiving enemy.

After consulting the students and the residency programs at which they were placed, Michigan State is one of the universities expediting the licensure of health care professionals entering the workforce from the colleges of Human and Osteopathic Medicine. For residencies in the state of Michigan, 61 students in MSU's College of Human Medicines graduating class are eligible.

If a residency or hospital wants to start their people early we are making that possible, said Dr. Aron Sousa, interim dean of the College of Human Medicine at Michigan State.According to Sousa, the students will be available as soon as May. He noted that early licensure is a choice that students can opt-in to. There are a lot of things that have to happen for this to work for people, he acknowledged, but that were just trying to make our people available to do good in the world.

Leadership at Oakland University's William Beaumont School of Medicine also havepresented early licensure as one option among several others, including research, telemedicineand volunteering opportunities, for fourth-year students. At present, the University of Michigan Medical School does not have plans to graduate doctors earlier than expected. Similarly, Wayne State School of Medicine will conduct graduation as scheduled for June 2.

Having residents start earlier than July 1 could relieve hospitals whose providers have become sick or exhausted, but poses additional logistical challenges and an increase of work to onboard new staff. A University of Michigan spokesperson confirmed that residency programs at Michigan Medicine will not start earlier than scheduled, stating, starting the new doctors in their usual time sequence and orientation this summer will allow the faculty physicians now focused on the urgent pandemic patient care needs to maintain that focus.

Graduates across the state are staying prepared for either scenario.

No one truly ever feels prepared for residency, said Craig Matisoff, a Michigan State College of Human Medicine student who matched at Spectrum Health in Grand Rapids. It is a really difficult transition in the best of times, and I think this (pandemic)has just compounded a lot of those feelings. At the same time, it is hard to just sit on the sidelines knowing that we are capable, we have been prepared and are ready to contribute.

Matisoff said he would welcome the opportunity to begin earlier if needed:Im happy to support the folks here in west Michigan, but I would be lying if I said I wasnt nervous about the whole prospect as well.

Safetyand the possibility of becoming a vector for the virus, is a primary concern. Tony Gjocaj, who matched in family medicine at Beaumont HospitalWayne, has been following its response to COVID-19 on the hospital's Instagram to get a sense of if it may need additional support in the coming months. While that location initially intended to convert to a center specifically for COVID-19 patients, staff has now been deployed to other hospitals in the Beaumont system and Wayne is serving as a reserve hospital in case of a surge.

Gjocaj has already submitted the required paperwork for early licensure, but hesitates to say for certain whether he would elect to start his residency early.

I think I would. I would if I knew the proper PPE (personal protective equipment) was in place and it was safe to do so. That is the No. 1 thing. We do not want to hurt people by contracting the virus ourselves and spreading it to others, he explained. Quoting the oath he has yet to take at graduation, do no harm, he said.

Some representatives from programs on the west and east side of the state say they do not anticipate a need to start first-year residents before the usual July 1 date. Major hospitals in metro Detroit, including Henry Ford Hospital, are in aStage 2: Increased Clinical Demands status in line with the updated guidance by the Accreditation Council for Graduate Medical Education (ACGME) in response to the pandemic. That status allows residents to focus solely on caring for the crucial surge of COVID-19 patients while educational activities are suspended.

Dr. Kimberly Baker-Genaw, vice chair of Internal Medicine and director of Medical Education at Henry Ford Hospital, said she is optimistic that countermeasures will continue to flatten the curve, and it will not be necessary to disrupt asmuch day-to-day education and patient care activities to direct all staff to COVID-19 care, even given a possible surge in the fall.

Im hoping in the fall that we do not see this surge, she added, but if people dont socially distance and we see the resurgence of the spread like we had initially I think it is possible again.

It remains unlikely that residents will be dispatched to field hospitals, such as the ones recently erected at the TCF Center (formerly Cobo Center) in Detroit or at the Suburban Showplace Collection in Novi, unless the state sees another extraordinary surge in cases.

There are so many variables at play that LaVana Greene-Higgs, who is part of both the University of Michigan Medical Schools graduating class and the incoming residency cohort, is unsure of how to brace herself for what comes next. She articulates the question hanging over the class of 2020:Im trying to figure out what it looks like to begin training in a pandemic. Until then, she is staying up to date on the guidelines and recommendations for COVID-19 treatment.

LaVana Greene-Higgs, graduating U-M medical student and incoming resident at Michigan Medicine poses for a photo in Ann Arbor, Wednesday, April 22, 2020.(Photo: Junfu Han, Detroit Free Press)

Wayne State student Andrew El-Alam, who matched in emergency medicine at Henry Ford Hospital, hopes that by his July start the incoming coronavirus cases are at a more manageable level.

Ive come to terms that this is likely going to be here for a long, long time. But hopefully not at this level, he said. El-Alam said he felt suited for emergency medicine after growing up working in his parents restaurant, and pursued the specialty out of a desire to help people at their most vulnerable.

Dr. Candace Smith-King, vice president for academic affairs at Spectrum Health, aims to have adjusted to a new normal before residents begin in July. COVID-19 is not going to just disappear, were going to have to learn how to function with it within our health care system, she explained.And how we do that as a health care system has yet to be determined.

The incoming class of residents are asking that central question, too, and will play a role in answering it. They can expect to care for COVID-19 patients until a treatment is determined or a vaccine is available, but could also see sicker than normal patients who may have been impacted by the consequences of prolonging care. Residency programs may transition some of the orientation process to be held virtually, but plan to begin patient care uninterrupted in July.

Theyre coming into a situation where there is more uncertainty, Smith-King acknowledged.They may learn medicine differently. The hospital may look different. Those details are yet to be understood all the way. But theyll still be the ones going in to take care of patients. Theres no way, really, for our hospital to function without them. They are an integral part of what we do.

Matching into the obstetrics-gynecology residency at Beaumont HealthRoyal Oak was fulfilling a lifelong dream for Alison Thomas, particularly since 23 of her cousins were born there. Thomas, who will be graduating from Oakland University's William Beaumont School of Medicine, has expressed to the university her interest in their option to graduate early and plans to remain flexible.

Alison Thomas of Orchard Lake is seen outside of her home on Tuesday, April 21, 2020. Thomas is at the Oakland University William Beaumont School of Medicine and has expressed to the university her interest in their option to graduate early and plans to remain flexible. Alison matched into the obstetrics-gynecology residency at Beaumont Health, Royal Oak where twenty-three of her cousins were born.(Photo: Ryan Garza, Detroit Free Press)

Thomas has braced herself, knowingthat the pandemic will shape the start of her medical career. It is definitely an added stressor," she said.But this is history.

She acknowledged that it is an amazing opportunity to learn how to handle and work through a pandemic. In the end, its just going to help me learn more and help me be more equipped if this ever happens again. And, as she says, Moms will still be delivering their babies regardless of whether were in a pandemic or not.

For all, this moment in time represents precisely why they chose to become doctors. In just a few weeks, the graduating classes will take the Hippocratic Oath for some, only quietly to themselves reciting, And may I long experience the joy of healing those who seek my help.

The vice dean of Medical Education at Wayne State University School of Medicine, Dr. Richard Baker, has confidence in the class of 2020. As he says, Wayne State is graduating 290 leaders.

This is a heroic time. They will be heroes, whether they want to or not. Its scary, Baker said, adding, This experience for this cohort of students going to residency will probably change them forever. But theyre up to the task.

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$30M gift to establish the Elizabeth Weiser Caswell Diabetes Institute at the University of Michigan – University of Michigan Health System News

Press release authored byTiffani Langford

ElizabethWeiserCaswell and Regent Ron Weiser

ANN ARBOR, Mich. Regent Ron Weiser and his wife, Eileen, of Ann Arbor, have committed $30 million to the University of Michigan for diabetes research and the development of life-changing diabetes therapies at Michigan Medicine, in collaboration with other University of Michigan schools and units for diabetes research. The gift named for Regent Weisers daughter who has two sons and a husband with Type 1 diabetes (T1D) will be used to establish the Elizabeth Weiser Caswell Diabetes Institute, pending approval by the Board of Regents, and advance U-M faculty-led collaborative projects that have the potential for rapid clinical application.

Elizabeth has been a relentless educator and advocate for people with diabetes and for diabetes research, said Regent Weiser. Our family hopes that the collaboration among physicians, researchers, innovators and advocates across campus will allow the work shes done and continues to do to be rewarded with cures for diabetes. She has served tirelessly on behalf of the diabetes nonprofit JDRF and will be a member of the FY21 JDRF International Board of Directors and vice-chair of the JDRF Research Committee.

The Elizabeth Weiser Caswell Diabetes Institute will centralize and coordinate campus resources anchored by a group of more than 250 world-renowned, dynamic researchers in diabetes, diabetic complications, obesity and metabolism and allow U-M to bring new depth and discovery to the quest for answers to diabetes.

This is one of the most important things that has happened for diabetes research, not just for the University of Michigan, but for the whole country, said Martin Myers Jr., M.D., Ph.D., director of the new institute. The institute is built on the idea that we cant only study one aspect of diabetes, but rather that we need to work together to attack every piece of this disease at the same time. Thus, we will simultaneously work toward making designer insulin-producing beta cells as a therapy for diabetes, seek to understand how to block the onset of Type 1 and Type 2 diabetes, and focus on how to improve clinical care and access to current lifesaving therapies.

And, to ensure that a new generation of researchers are trained to continue investigations that mitigate the impact of T1D, Elizabeth and her husband, Trey, also partnered with Regent Weiser and Mrs. Weiser to establish the Caswell Family Fellowship in pediatric endocrinology, part of the $30 million commitment.

The Weiser family has a long history of championing the work of faculty and teams at the University of Michigan through their generosity and proliferation of vital partnerships, said U-M President Mark Schlissel. This gift will ensure that U-M is able to translate scientific discoveries into treatments for diabetes that save lives in our community and beyond. I am personally touched by the way this family has translated their personal experience with diabetes into hope for all people, and grateful for their confidence in U-Ms promise to make a difference.

Ron and Eileen Weiser are longstanding U-M alumni, volunteers and donors, committing more than $100 million to the university to date. In addition to Ron Weisers service on theU-M Board of Regents, they both served as vice chairs of theVictors for Michigan campaignand support a wide range of programs across all three campuses of the university, including the Weiser Center for Real Estate, the Weiser Diplomacy Center, theWeiser Center for Emerging Democracies, theWeiser Center for Europe and Eurasia, Michigan MedicinesMary H. Weiser Food Allergy Centerand theChad Carr Pediatric Brain Tumor Cancer Center, among other programs. TheCollege of Literature, Science, and the Arts;Michigan Medicine;School of Music, Theatre & Dance;UM-Dearborn; Ross School of Business; Ford School of Public Policy; and dozens of other units have been beneficiaries of the Weisers generosity.

The Elizabeth Weiser Caswell Diabetes Institute will build on best practices of the standout programs developed at U-M and other top institutions. As part of the top public university in research spending in the United States, and in partnership with 20 divisions and departments within Michigan Medicine and 14 schools and units across the U-M campus that focus on diabetes care and research, the Elizabeth Weiser Caswell Diabetes Institute will strengthen U-Ms leadership nationally and globally in this space. Several national and international collaborators will work with the U-M and Michigan Medicine teams.

This gift is transformational, said Marschall S. Runge, M.D., Ph.D., executive vice president for medical affairs, dean of the University of Michigan Medical School and CEO of Michigan Medicine. We are immensely grateful to the Weisers for opening the doors that enable our physicians and researchers to push the boundaries that will transition cutting-edge discoveries in diabetes investigations into lifesaving therapies for children and adults.

Michigan Medicine is known for excellence in research and care for those with diabetes and the complications that it causes.

Diabetes is so hard. You dont want to think about complications, but you know theyre out there, said Elizabeth Caswell, of Ann Arbor. Diabetes doesnt allow anybody to shut down and forget about it; theres no break. Fortunately, the team at Michigan Medicine has been there for us every step of the way advising us on daily care, advances in treatment technologies, and opportunities for clinical research. Until T1D is cured, we are grateful for top-notch care at one of the best research institutions in the world.

About Michigan Medicine:At Michigan Medicine, we advance health to serve Michigan and the world. We pursue excellence every day in our three hospitals, 125 clinics and home care operations that handle more than 2.3 million outpatient visits a year, as well as educate the next generation of physicians, health professionals and researchers in our U-M Medical School.

Michigan Medicine includes the top ranked U-M Medical School and the University of Michigan Health System, which includes the C.S. Mott Childrens Hospital, Von Voigtlander Womens Hospital, University Hospital, the Frankel Cardiovascular Center and the Rogel Cancer Center. Michigan Medicines adult hospitals were ranked no. 11 in the nation by U.S. News and World Report in 2019-20 and C.S. Mott Childrens Hospital was the only childrens hospital in Michigan nationally ranked in all 10 pediatric specialties analyzed by U.S. News and World Report for 2019-20. The U-M Medical School is one of the nations biomedical research powerhouses, with total research spending of more than $500 million annually.

More information is available at http://www.michiganmedicine.org

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Mother-daughter duo begin their medical careers together – Insider – INSIDER

Dr. Cynthia Kudji Sylvester and Dr. Jasmine Kudji caught national media attention in March 2020 for becoming the first mother-daughter duo to attend medical school at the same time at the same institution.

The two will now be continuing their career journeys together as medical residents in the Louisiana State University Health System Kudji Sylvester at LSU Health Lafayette as a family medicine resident and Kudji as one of 11 incoming surgical residents at LSU Health New Orleans.

For 49-year-old Kudji Sylvester, this dream has been 27 years in the making.

Kudji Sylvester's family moved from Ghana to Louisiana when she was two-years-old. She told USAToday she was inspired to become a doctor during a visit back to West Africa with her family. When a young woman approached Sylvester and her mother asking them to help her sick child, she was deeply moved.

"I've always wanted to be a physician," Kudji Sylvester told USA Today. "Seeing that disparity really, it shook me, you know, and it made me want to do something about it."

However, Kudji Sylvester had to pause her dream of becoming a doctor when she became pregnant with her daughter when she was 22-years-old. She instead started out her career as a nursing assistant before she became a registered nurse two years later.

"I had to put my dream of being a physician on hold because I needed a job. I needed to bring in an income. And so that's where being a nurse came in."

Kudji grew up visiting her mother in hospitals and watching her work as a nursing assistant.

"Being exposed to patients and being exposed to medicine at such an early age, it wasn't really something I just decided to do. It's just something that was always a part of my life, so much of it was just natural," Kudji told USA Today.

Seeing her mother care for patients inspired her to want to pursue a career in medicine which she did as she attended LSU New Orleans for her undergraduate degree.

While Kudji was seeing to her undergraduate studies, Kudji Sylvester rekindled her dream to become a physician and enrolled in the University of Medicine and Health Sciences on the eastern Caribbean island of St. Kitts when she was 43-years-old.

"When Jasmine was in college, I was like, you know what, this is the perfect time for me to pursue my dream of being a physician," Kudji Sylvester told USA Today.

When Kudji graduated undergrad, she Kudji followed suit two years after her mother enrolled in med school by attending the same institution.

"The thing that's difficult about medical school is that not everyone truly understands what you go through during those four to five years that you're there. So having my mom be the person who does understand that was great. You're just able to rely on each other throughout the entire process," Kudji said.

Dr. Cynthia Kudji Sylvester and Dr. Jasmine Kudji Adrienne Battistella / New Orleans

In 1864, Dr. Rebecca Crumpler became the first Black women in the United States to earn a medical degree. Sadly, in those 156 years, the number of Black doctors in the United States haven't risen to even match the population of Black people in the US.

According to the Association of American Medical Doctors, only 5% of doctors identify as Black or African American as of 2019, despite Black Americans making up 13.4% of the US population in 2019 on the US Census.

This disparity inspired Kudji Sylvester and Kudji to create a blog called "The MD Life" to show young Black girls in particular that a medical degree is attainable and inspire them to pursue a career in medicine.

"When you're young and you don't see someone that looks like you doing something that you want to do, when you see other people doing it, you kind of start to think well, maybe these people are inherently somehow better than me," Kudji told USA Today.

"That's why I think representation matters. It shows young people or even older people that, no, there's nothing inherently wrong with you, you're not less intelligent or less capable. You know, you can do it too."

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There’s a pandemic and a physician shortage. In Michigan, more people are applying to med school – Lansing State Journal

EAST LANSING Going to medical school was always part of the plan for Mohaymin Kadir.

He grew up in Hamtramck where many of his neighborslackedaccess to affordable medical care and affordable nutrition. Sometimes, he did, too.

Kadir's sense of the health care system'sdeficiencies was only sharpened during his studiesat the University of Michigan, where he earned a master's degreeinpublic health focusing on epidemiology.

I learned more about the disparities and how they cement themselves, said Kadir,who was born inBangladesh. We need more diversity in medicine and more representation to sustain positive change in medicine.

Which is why he'sstarting this fall at the Michigan State University College of Human Medicine, one ofthousands of hopefuls who submittedapplications to the College of Human Medicine and other medical schools around the state, one of the successful ones.

Lots of people want to be doctors these days.

Nearly 9,000 prospective students have applied for seats in the next 190-student class, said Joel Maurer, assistant dean of admissions for the MSU College of Human Medicine,up from 7,959last year.

For the entering class of 2019, six of Michigan's medical schools received 43,602 applications,up 4,193 from 2018 and up 15,157 from 2014. These numbers likely reflectprospective students submitting applications at multiple medical schools.

The number of applicants nationwide trying to get into medical schools also grew, hitting53,371 prospective studentsin 2019. That comparesto 49,480 in 2014 and 33,623 in 2002.

This means more people are vying for spots in what's become a significant competition. To meet the demand, some schools increased their class sizes or are considering expanding.

TheCMU College of Medicine accepted 64 students for its first year in 2014 and increased the class size to 104 for each year since, Austin said.

The medical schoolcould consider adding 20 more spots to the incoming class in 2021, he said.

TheWestern Michigan University Homer Stryker M.D. School of Medicine, a private school affiliated with WMU, first accepted a class of 54 students who graduated in 2018. Since then, the class size has grown to 60, to 72 and now to 84 students, according toJean Shelton, WMed assistant dean of admissions and student life.

A sign at the Michigan State University campus in East Lansing, Michigan.(Photo: LSJ file photo/Derrick L. Turner)

Some schools, like the MSU College of Human Medicine, say they're at capacity with their current class size of about 200 students. Hiring more faculty and adding more training space and buildings at their East Lansing and Grand Rapids campuses would be the only way to increase the class size, Maurer said.

They may have to consider changes as more people apply.

The University of Michigan Medical School saw 7,896 applications submitted in 2019, about 2,269 more than in 2011.

Medical schools across the board have seen more and more applicants in recent years, including the MSU College of Osteopathic Medicine, which received 6,653 applications in the last window, said Katherine Ruger, the college's associate dean of admissions and student life. That's up from the 6,169 applications in 2019 and a growth from 5,015 in 2014.

Enrollment officials from different medical schools pointed to a variety of reasons for the trend. Ruger suspects this year's applicants had more time for submissions since COVID-19 shut downs reduced their opportunities for traveling, working or volunteering.

The MSU College of Human Medicine's efforts to increase marketing and recruitment and additional work to increasepublic interest in science, medicine and human service may have helped, Maurer said.

It was the human service aspect and helping the underserved, an element of the College of Human Medicines mission statement, that brought Momodou Gobi Bah across the world to pursue a career in medicine.

He grew up in Gambia, a country in western Africa where Bah said there aren't enough hospitals and medical facilities. Hedreamed of studying medicine at a university and coming back to help his country.

Momodou Gobi Bah will train to become a physician at Michigan State University's College of Human Medicine starting this fall.(Photo: Momodou Gobi Bah)

I would love to know, looking at a patient, that I can help them and two weeks later the patient gets better, he said. Its a powerful feeling and I want to be a part of that world.

Central Michigan University began training future physicians in 2013. Thenumber of applicants has jumped every year since.

That first year, 2,765 students applied. The 2019 application window hit 7,442 applications, with nearly 7,000 applications so far for 2020.

Wayne State University School of Medicine, the only medical school in Detroit, may be helped by its urban environment, said Kevin J. Sprague, associate dean for admissions and enrollment management.

Wayne State has seenthe number of applicants nearly double since 2014, when the medical school received 4,588 applications, according to Sprague. In 2019, the number hit 9,993.

Wayne State is an excellent school in an inner-city, urban environment, Sprague said. Its an excellent place for medical education.

More applicants could mean more doctors to address the country's physician shortage.

In an April 2019 study, the Association of American Medical Colleges projecteda total physician shortage nationwide of between 46,900 and 121,900 by 2032. Included in that is a projected primary care physician shortage of21,100 to 55,200 physicians.

The growing number of applicantsis a good sign for those concerned about the coming shortage, saidGeoffrey Young, senior director ofstudent affairs and programs for the Association of American Medical Colleges.

"It really demonstrates a strong interest in a career in medicine," he said. "This is what we think is critical as the nation faces a shortage of physicians."

And at CMU, Austin expects the COVID-19 pandemic will motivate even more people to go into the medical field, bringing another spike in applications.

Seeing more and more people succumb to the coronavirus made Khaleel Quasem more determined than ever to enter the fight.

The MSU College of Human Medicine accepted Quasem, from Marquette, into its next class of future physicians. He comes from a family of doctors, including his father and several uncles, but he didnt feel pressure to follow in their footsteps.

Rather, thepath leading him to medical educationstarted when he wasa food service worker in the University of Michigan health system. He later becamea phlebotomist. It was when he began shadowing physicians at Memorial Endocrinology in Owosso and Marquette Internal Medicine and Pediatric Associates that it became clear the career he would choose.

Watching physicians helping the thousands of patients diagnosed with COVID-19 and making dramatic changes to work styles so they can continue caring for patients fighting the contagious disease madehim want to be a part of it.

In the end, we will get through the coronavirus pandemic, but only in a way that we would be much better off than we were before, Quasem said. In a decade from now, health care education will look back on this and use it as a lesson on what we did right, what we did wrong, and how to combat a situation if it happens again.

Eneka Lamb(Photo: Eneka Lamb)

The pandemic has highlighted howeasily public health can be politicized, which disappointed Eneka Lamb, who once thought medicine was apolitical.

Still, political infighting over the disease hasnt pushed Lamb away from pursuitof a medical career. She came from Hong Kong to complete her undergraduate education at Duke University and now plans to start at the MSU College of Human Medicine in the fall. The coronavirus galvanized her desire to become a doctor.

I really dont fear going into the medical field, she said. I feel a little bit antsy. I want to hit the ground running as quickly as possible.

For many students entering medical school this comingfall, helping with future disease outbreaks is just a piece of why they chose to study medicine.

Kadir still doesnt know the area of medicine he wants to specialize in. Maybe infectious disease, he said, or a public health specialty.

He hopes to shine a light on the health disparities many people face, especially people of color. COVID-19 helped bringthe issue to light death rates were higher in communities with larger populations of African-Americans and other people of color, according to Centers for Disease Control and Prevention.

People who have looked into it have always been aware of it, Kadir said. I think having more people from that background in positions of power is key to sustain change.

Contact Mark Johnson at 517-377-1026 or atmajohnson2@lsj.com.Follow him on Twitter at@ByMarkJohnson.

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There's a pandemic and a physician shortage. In Michigan, more people are applying to med school - Lansing State Journal