Chemistry challenge 'a wonderful way to promote academics'

Protons. Neutrons. Cyclotron. Electrons. These were only a few words in 302 questions asked of 16 sixth- through eighth-grade students from two counties who participated in the eighth annual, You Be the Chemist Challenge this week at Seneca Grade School. Eight middle schools from Oglesby, Mazon, Minooka, Seneca, Morris and Coal City participated. By the time the regional competitions are over, about 12,000 students from 19 states will have participated.

Before the contest, Mark Biel, executive director of the Chemical Industry Council of Illinois, presented a check on behalf of Air Products and Chemicals to teacher Glen Flodstrom (Washington Junior High, Oglesby). His students have won many of the state's previous competitions.

The national competition will be Monday, June 25, at the Kimmel Center in Philadelphia. State winners will have the opportunity to visit the Franklin Institute and the National Constitution Center, an interactive history museum.

Fran Ogden, science teacher at Seneca High School, was the question reader for the evening. Accumulated each year by teams of scientists, graduate students and others who work through the national contest organizers (Chemical Educational Foundation), the questions are saved in question banks and not used again for five years.

"The banks get bigger and bigger each year as it gets harder to stump the students who come to this contest," the event's facilitator, Patricia Neff, said.

Five judges took turns asking the students questions. Once a question was asked, they had 15 seconds to raise their hands before holding up a multiple choice answer. There were 10 questions in each round.

Barium, one of the answers, provided some humor to the evening. "What do you do with a dead body?" Byrne asked the students and audience. "You Bar-i-um."

"This is a very big deal," Mazon-Verona-Kinsman science teacher Darcy Welsh said. "This event is a great way to recognize kids. The chemical industry is very big in Illinois and it's one of the major employers, so this is a very good way to generate interest in our kids."

First place was worth $500; second place, $250; and third place, $100. All contestants took home a $25 gift certificate and a bag of donated items from Aux Sable Liquids, Exelon-Dresden, Flint Hills Resources and Akzonobel.

"I hire a bus to take all the contestants and their fans to the state competition," Event Coordinator Patricia Neff said. "We'll be touring the UOP Research Complex (a petrochemical technology firm with headquarters in Des Plaines). They will probably visit their electron microscope room, glass blowing and knock labs. This is a great way for students to see research in progress."

Seneca Grade School South Campus Principal Shane Severson was proud of all the students.

"We are honored to host this event every year and always glad to help out Pat (Neff) and all of the event sponsors," he said. "We look forward to hosting future competitions that promote kids using their brains.

"Meet the Chemist is a wonderful way to promote academics. We're just very proud of all the efforts all the students made in this competition. We're looking forward to the school's students moving on to the April 3 state competition."

Second place regional competition and first place La Salle County: Lyle Marshall, Seneca Grade School, eighth grade.
First place regional competition and first place Grundy County: Conrad Goffinet, Minooka Junior High, eighth grade.
Third Place regional competition and second place La Salle County: Aaron Kamke, Waltham Elementary School, eighth grade.
Second Place Grundy County: Jared Roth, Saratoga Middle School, seventh grade.
Third Place Grundy County: Nick Micetich, Coal City Middle School, eighth grade.
Third Place La Salle County: Jakob Selquist, Parkside Junior High, eighth grade.
Alternate for Grundy County: Joey Rivera, Coal City Middle School, eighth grade.
Alternate for La Salle County: Grant Granby, Seneca Elementary, eighth grade.

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Chemistry challenge 'a wonderful way to promote academics'

Durham Graphene Science secures extra funds

Graphene

Congratulations are in order for Karl Coleman the Chemistry World Entrepreneur of the year 2011. Not for winning our prize (which is great, of course, but we announced that back in July 2011 so it is old news really…) but for securing a significant amount of funding for his spin-off company Durham Graphene Science (DGS).

Coleman who is a reader in the chemistry department at Durham University, UK, and who received last year’s accolade for ‘his development of new intellectual property for the production of graphene ans its commercial exploitation’,  has just received the news that North East Technology fund, IP Group and Northstar Ventures have committed £1.2 million worth of investment money to DGS.

The company, which was founded less than 2 years ago in August 2010, is a spin out of Durham University and was created by Coleman  to commercialise the manufacture of graphene flakes using chemical vapour deposition. For those who may be interested, you can read all about it in the feature we wrote in September. My question for Dr Coleman is: how much closer does this bring us to be making graphene by the kilo?

Bibiana Campos-Seijo

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Chemistry not enough to overcome ‘Vow’ clichés

By Michael Huckaby / movie reviews

Vivacious Rachel McAdams and “boy next door” Channing Tatum are perfectly cast for a serious romantic drama. But the dimpled McAdams and clean-cut Tatum chemistry can’t overcome a ridiculously contrived and cliché-ridden plot – a shallow groaner. They star as Leo and Paige, a couple whose marriage is torn asunder when a head injury gives her amnesia. However, her peculiar brain trauma is selective, conveniently wiping out only the most recent and happy years of her memory. Leo’s ill-advised but noble way of handling this five-year gap is the sputtering engine that drives the story.

The supporting cast is an underutilized asset, most notably Jessica Lange and Sam Neill as Paige’s self-centered parents Rita and Bill. Set in Chicago, the locales are interesting and the production values good. While the flashbacks provide the movie’s most engaging scenes, Leo’s narrative intros – philosophical attempts to be profound — are distracting.

The opening scene introduces Paige and Leo as they leave the old landmark Music Box movie house snuggling on a snowy evening. After scraping their car windows, they take off and – while being lovey-dovey at a stoplight — are rammed from behind by a snowplow. Paige goes flying (in slow motion) through the windshield. Knocked unconscious, Leo’s injuries are superficial.

What Paige remembers when she wakes up in the hospital is being the socialite daughter of a wealthy Lake Forest attorney. A law student at Northwestern, she is happily engaged to Jeremy (Scott Speedman). She mistakes her husband of four years for her surgeon. Nor does she remember being estranged from her parents, dropping out of law school, enrolling at the Chicago Art Institute and becoming a renowned sculptor with a commission backlog.

When Rita and Bill arrive at the hospital, Leo meets them for the first time. Aware of the extent of Paige’s amnesia, they take advantage of her memory loss and attempt to persuade her to come home. Convinced her memory will come back, Paige agrees to live chastely with Leo, the owner of a small recording studio.

Though Paige is put off by a welcome home party of friends she doesn’t remember, Leo convinces her they were happy, visiting their favorite romantic haunts and showing her photos of their unconventional wedding.

Cluttered with antiques, the charming Café Mnemonic provides the setting for one of the best romantic scenes. For dessert, they liked to split and sample a box of chocolates – another magic moment she doesn’t recall. As for their quirky art museum wedding, the museum was forbidden and the entire wedding party had to hightail it when a guard appeared.

Drawn to Lake Forest by the coming wedding of sister Gwen (Jessica McNamee), Paige identifies more with her childhood environment than the Bohemian lifestyle she has forgotten.

Meanwhile, Leo and his stalwart assistant (Tatiana Maslany) have a business to run. Always ready to make Paige his priority, Leo just looks on as her parents gain the upper hand – knowing but unwilling to tell her why she avoided her entire family for the last five years. Can the marriage be saved when Gwen slips and reveals the truth?

Inspired by a true story, only the outcome is comparable.

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Chemistry not enough to overcome ‘Vow’ clichés

Research and Markets: Future French Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and …

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/f490ba/future_french_clin) has announced the addition of the "Future French Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and Business Expansion Strategies" report to their offering.

This report presents a comprehensive analysis of the French clinical chemistry and immunodiagnostics markets, including:

Major issues pertaining to the French clinical chemistry and immunodiagnostic laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years. Five- and ten-year volume and sales forecasts for over 100 clinical chemistry, TDM, endocrine, cancer, immunoprotein and abused drug assays performed in French hospitals and commercial laboratories, including controls, calibrators and consumables. Five- and ten-year volume forecasts for serum, whole blood, plasma, CFS, urine and other specimens. Five- and ten-year reagent and instrument sales forecasts. Review of current instrumentation technologies, and a feature comparison of 50 high-, medium-, and low-volume/POC analyzers. Sales and market shares of leading reagent and instrument suppliers. Review of current and emerging technologies and their potential market applications. Product development opportunities for clinical chemistry and immunodiagnostic instruments and consumables. Profiles of 25 current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. Market penetration strategies, entry barriers and risks.

The report contains 542 pages and 104 tables.

For more information visit http://www.researchandmarkets.com/research/f490ba/future_french_clin

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Research and Markets: Future French Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and ...

Howard Zimmerman, pioneer in organic chemistry, dies at 85

Feb. 16, 2012

Howard Zimmerman, a professor of chemistry from 1960 until his retirement in 2010, died on Saturday, Feb. 11 as a result of a fall.

Zimmerman

Zimmerman helped establish the field of organic photochemistry -- the study of how light affects and initiates chemical reactions.  By applying the theory of quantum mechanics to these reactions, he was able to develop predictive and explanatory theories. 

“Howard was a major figure in photochemistry,” says Bassam Shakhashiri, professor of chemistry. “His research was renowned worldwide; the American Chemical Society gave him awards, and asked him to give short courses. He was very dedicated, sharply focused on his research.”

Hans Reich, a professor of chemistry at University of Wisconsin-Madison who had a neighboring lab in the chemistry department, remembers “a larger-than-life figure in chemistry. He was a member of the National Academy of Science for many years; he was a real pioneer in the study of photochemistry and published hundreds of papers. He was a pioneer in developing theories of how these reactions work and how you can predict reactions logically instead of having to do experiments.”

Which is not to say that Zimmerman disdained experiments, notes Patrick Mariano, who was a member of the “Z group” in the 1960s. “He said a good experiment trumps everything else, and it would last forever, but the interpretation may only last for a decade,” he says.

Richard Givens, professor emeritus of chemistry at the University of Kansas, recalls that Zimmerman “had a way of reducing complex problems to very understandable ones. For those of us who were 21 years old, he was able to take very complex ideas and concepts, and reduce them to an easily understood form that could be used to solve problems. He was interested in the fundamental aspects of organic reactions, he developed breakthroughs in understanding photochemistry, in how molecules are raised to the excited state and why.”

One of Zimmerman's papers on reactions used by numerous synthetic organic chemists, “must among the most cited papers in the history of organic chemistry,” says Mariano, a professor of chemistry and biochemistry at the University of New Mexico.

Mariano also remembers Zimmerman as an excellent mentor. “He was unique in the intensity of his concern that his people get the best positions possible. And it did not stop there. Throughout my professional career, he remained intensely interested in my progress.”

Other former students stressed that mentorship as well.

“He was tenacious in his problem-solving and supportive of his students,” says Givens, who studied with Zimmerman in the 1960s. “He was very attentive to what we were doing in the lab, would visit frequently and ask how it was going. He was definitely a hands-on professor, he worked hard with you try to get to the solution of the research problem, to understand a reaction or synthesize a new compound.”

Laren Tolbert, who received his Ph.D. in 1975, recalls exacting standards in the lab. "He was a stickler for detail, for accuracy in well-run experiments, for making sure the data was there to support your claim."

“He was not a warm-and-fuzzy guy, and some viewed him as a very difficult taskmaster,” says Tolbert, a professor of chemistry at Georgia Tech. “He believed in the students working extremely hard, had low tolerance for slacking off, and was proudest of the ‘silver spatula award,’ given to the students who worked on holidays. But he was also very loyal. Once you got a Ph.D. from him, he would support you to the ends of the earth.”

“There would not be a single person who would disagree that he an extremely good mentor,” agrees Mariano.

At a symposium in his honor in September, Zimmerman “was in such good spirits and good health, he was sharp minded and gave fantastic talk,” says Mariano. “His death was a such shock.”

Zimmerman is survived by his wife, Peggy, and by three sons from his first marriage.

The chemistry department has established a fund at the UW Foundation for donations in Howard's memory.  Memorials can be made payable to the UW Foundation–Howard E. Zimmerman Memorial Fund, US Bank Lockbox 78807, Milwaukee, WI  53278.

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Howard Zimmerman, pioneer in organic chemistry, dies at 85

Jets aim to improve team chemistry

Updated Feb 16, 2012 10:31 PM ET

 

EAST RUTHERFORD, N.J. (AP)

In the wake of some very ugly finger-pointing after the season, several New York Jets veterans are trying to find ways to improve team chemistry.

Starting left guard Matt Slauson recently learned about the possible team bonding activities while talking to members of the Jets' developmental department.

Slauson has not spoken to fellow players about the activities, but he welcomed anything that would help bring the team closer after the drama following an 8-8 season.

''Absolutely we are all focusing on next year now,'' Slauson said Thursday after attending a news conference to announce that WrestleMania would be held at MetLife Stadium in 2013. ''We're not worried about all of that drama that happened last year. We are focusing on next year and getting better and doing what we can to get in the Super Bowl.''

After reaching the AFC title game in 2009 and '10, the Jets were one of the preseason favorites to make the Super Bowl this season. However, the team was inconsistent and missed the playoffs for the first time in Rex Ryan's three seasons as coach.

It got ugly after that.

Fans and the media criticized quarterback Mark Sanchez, and then some teammates and members of the organization anonymously questioned Sanchez's work ethic and leadership abilities in a Daily News story in early January.

Veteran running back LaDainian Tomlinson later said the Jets' locker room was as troubled as any he'd ever seen, adding that the problems got ''out-of-hand toward the end of the season,'' and were created by the brash approach of Ryan and general manager Mike Tannenbaum.

It's a problem that needs mending if the Jets are to get back on track next season.

''I have been talking to some guys about if we are going to do some team-building stuff and there are guys brainstorming right now,'' Slauson said of his conversations with the guys in the developmental department. ''But there is nothing official now.''

Slauson also disclosed Thursday at a news conference at the home of the Giants and Jets that he played this past season with a torn labrum, rotator cuff and biceps in his left shoulder. He has had surgery to repair them and expects to be ready for the season despite a projected six-month rehabilitation period.

A sixth-round draft pick out of Nebraska in 2009, Slauson has been the starting guard the past two seasons. He believes he hurt his shoulder in December 2010 in a game against the Patriots.

''I thought it was no big deal, the fact that I could play and still lift, kind of, I didn't think it was a big deal or anything was wrong,'' he said.

Slauson attended the news conference with teammates Donald Strickland, Kyle Wilson and Muhammad Wilkerson, and owner Woody Johnson. The Super Bowl champion Giants were represented by co-owner John Mara, long snapper Zak DeOssie and tackle David Diehl.

Slauson said watching the cross-town rival Giants win the NFL title against the Jets' other major rival, the Patriots, was weird.

''That's the cost of things,'' he said. ''You don't play well throughout the entire year you are not going to make it there. The Giants did a phenomenal job. Every team's goal is, whether they say it or not, their goal is to be in the Super Bowl. That's our goal and we fell short, but we are all excited about next year.''

While it's been nice enjoying the Super Bowl victory, DeOssie said the Giants realize that their offseason program starts in two months. He also noted that keeping the team together might not be possible.

''The reality is this is the NFL and guys move on and some guys stay,'' DeOssie said. ''I certainly do wish it's the exact same team, but I know that is not going to happen.''

Diehl came to the new conference with a bandage on his left hand. He had six screws inserted to fix a broken finger following the Super Bowl.

''I'll be all good,'' said Diehl, who started the first 10 games at left guard and the last 10 at left tackle after Will Beatty had surgery to repair a detached retina. ''I'm happy. This is the time to heal up and rest, anyway. I'm looking forward to getting started again and getting rolling here pretty soon.''

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Jets aim to improve team chemistry

The Physics And Chemistry Of Champagne Bubbles

February 14, 2012

The innermost secrets of champagne bubbles are about to be unveiled in the Springer journal EPJ ST. This fascinating work is the brainchild of Gérard Liger-Belair, a scientist tackling champagne bubbles from both a physics and a chemistry perspective. Based at the University of Reims, in the heart of the region that gave champagne its name, the author is appropriately affiliated with the ‘effervescence team of the molecular and atmospheric spectrometry group’ and the ‘oenology and applied chemistry’ laboratory.

To understand what appears to be a harmless phenomenon such as the fizz in champagne, the author studied the role of the carbon dioxide (CO2) throughout its journey from the bottle to the glass. Precisely, Liger-Belair focused on the second fermentation stage, resulting in the CO2 dissolution into the wine – aided by the addition of yeast and sugar before sealing each champagne bottle – to the stage where the gas escapes through tiny bubbles popping on the surface of the wine in the glass.

Armed with a high-speed camera, the author produced a series of visually appealing close-up snapshots of the hidden life of these bubbles at every stage of their short existence to analyze the forces at play. He first explained the process underlying their birth through a process called nucleation, triggered by the tiny impurities inside the champagne glass. He then followed their rise and attributed their extinction when they burst on the surface of the liquid in the glass to the cohesive forces between molecules of the liquid called surface tension.

Understanding the source of fizz provides clues on how to fine tune champagne production. For example, the bubble size can be reduced by a factor that can be calculated by taking into account fermentation sugar levels. However, the method remains fundamentally the same as the one developed by the 17th century Benedictine monk Dom Pierre Pérignon.

Reference: Liger-Belair G.,The Physics behind the Fizz in Champagne and Sparkling Wines, European Physical Journal ST (EPJ ST) 201: 1, DOI 10.1140/epjst/e2012-01528-0

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The Physics And Chemistry Of Champagne Bubbles

A Chemist Uses Google's Algorithm to Determine the Structure of Molecules

Scientists want to find a use for PageRank in the world beyond the web.

Chemistry is a science of links. Atomic units, made into more than they are by attractions and connections and bonds, all in a constant flurry of motion and change.

Sounds a little bit like the Web, doesn't it? 

Aurora Clark, an associate professor of Chemistry at Washington State University, thinks so. She noticed that there's a probabilistic nature to molecular links: Some are stronger, and more likely to materialize, than others. Which is, broadly, the logic that guides the guiding algorithm of Google search: PageRank. While the mathematical ingredients of Google's most-secret secret sauce are a closely guarded secret, the algorithm's broad approach -- the quantification and prioritization of links to determine a structure based on mutuality and relevance -- is ripe for the borrowing. 

moleculaRnetworks contains novel analysis algorithms and techniques unavailable elsewhere. These include graph theory-based analyses of network structure, including clustering of solvent molecules, and connectivity information such as PageRank (PR). PR, most famously used by Google to evaluate the importance of websites on the Internet, is used here as a descriptor of H-bonding structure and is unique to this toolkit. The scripts further use PR to instantaneously identify the geometric organization of the solvent about the solute, so that the dynamics of solvent shells can be monitored ....

Though the algorithm uses water as its test case, the molecule's ubiquity in living things means that moleculaRnetworks has potential uses beyond chemistry. The model could, Clark says, help scientists to understand how diseases spread in the human body -- and, therefore, to understand how medicines might be optimized to fight them. More broadly, the algorithm offers a nice lesson in the power of cross-pollination between technology and academia -- a link that Google, of course, has embodied from the start. 

Image: The Journal of Computational Chemistry.

More From The Atlantic

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A Chemist Uses Google's Algorithm to Determine the Structure of Molecules

Sirona Biochem Appoints Three Chemistry Experts to Subsidiary Scientific Advisory Board

VANCOUVER, BRITISH COLUMBIA--(Marketwire -02/14/12)- Sirona Biochem Corp. (TSX-V: SBM.V - News)(Pinksheets: SRBCF.PK - News)(Frankfurt: ZSB.F - News), a biotechnology company specializing in carbohydrate chemistry technology, announced today it has appointed organic chemistry expert Professor Pierre Vogel, fluorine chemistry expert Dr. Bernard Langlois and carbohydrate chemistry expert Dr. Eric Leclerc to the Scientific Advisory Board of its subsidiary, TFChem.

"These respected chemists will bring a tremendous amount of scientific insight to our research efforts," said Dr. Howard Verrico, President and CEO of Sirona Biochem. "This expertise will help to streamline our processes in compound development, selection and formulation and give us a better understanding of the compounds' commercial relevance," Dr. Howard Verrico added.

Biography of Professor Pierre Vogel

Dr. Pierre Vogel has been a Professor of Organic Chemistry at the Ecole Polytechnique Federale de Lausanne, Switzerland since 2001. In 1969, he completed his Ph.D under the supervision of Prof. H. Prinzbach at the Institute of Organic Chemistry, University of Lausanne. Dr. Vogel spent two years at Yale University, New Haven, Connecticut, USA with Prof. Martin Saunders, Prof. J. A. Berson, K. A. Wiberg and P.v.R. Schleyer (Princeton Universtiy). He then worked as a Research chemist at Syntex S.A., in Mexico with Prof. P.Crabbe before returning to the University of Lausanne in 1973. As of 1977 he became Professor of organic chemistry at the University of Lausanne. In 1991 he was Vice-Chairman of the Institute of organic Chemistry, University of Lausanne until 2001. He was also a part-time graduate school teacher at the Universities of Rouen and Caen from 1991 to 1993 and part-time professor at Ecole Polytechnique de Palaiseau from 1993-2000. Dr. Vogel has authored over 520 publications in referred journals.

Biography of Dr. Bernard Langlois

Dr. Bernard Langlois is a scientific expert in the area of organic fluorine chemistry with more than 40 years of academic experience. Until recently, he was the Director of the SERCOF laboratory at the University of Lyon in France as well as the Research Director for CNRS at the Universite de Claude Bernard. D. Langlois has been involved in organic fluorine chemistry since 1970, when he joined the research team of the Rhone-Poulenc Co. His interest is directed to all aspects of organic fluorine chemistry; aromatic and aliphatic compounds, fluorination and trifluoromethylation techniques, as well as functionalization of fluorinated substrates. During his career, he developed new methods for performing radical perfluoroalkylation using "Halons" or sodium trifluoromethanesulfinate, mild nucleophilic trifluoromethylation with fluoral hemiaminals or hydroxytrifluoroacetamides, as well as nucleophilic trifluoromethoxylation. He was also involved in work on a new route to triflic acid from bromotrifluoromethane. Dr. Langlois is the author of more than 90 articles, 9 book chapters, 33 patents, 60 poster presentations, 69 oral presentations and 39 invited and plenary lectures in national and international events. Dr. Langlois received his PhD from the University of Lyon (France).

Biography of Dr. Eric Leclerc

Dr. Eric Leclerc is currently a Centre Nationale de la Recherche Scientifique (CNRS) Researcher at the Institut Charles Gerhardt in France. In this role, Dr. Leclerc is responsible for the development of new tools for the synthesis of fluoroolefins and metabolically stable, fluorinated glycomimetics as analogues of glycoconjugate with high therapeutic potential. Prior to this role he was a Researcher at the Institut National des Sciences Appliquees (INSA) de Rouen, also in France, where he was responsible for the development of fluorinated glycomimetics and synthesis of chiral ligands for asymmetric catalysis. Previous positions include a post-doctoral role at the University of Hawaii at Manoa and a PhD position at the Universite Pierre et Marie Currie. Dr. Leclerc has authored more than 20 publications and has given several presentations in the area of fluorinated glycomimetics. He received his PhD and Masters in organic chemistry from the Universite Pierre et Marie Currie in 2001 and 1997, respectively.

About Sirona Biochem Corp.

Sirona Biochem is a biotechnology company developing diabetes therapeutics, cancer vaccine antigens, skin depigmenting and anti-aging cosmeceuticals and biological ingredients. We are applying a proprietary chemistry technique to improve the pharmaceutical properties of our carbohydrate-based molecules. For more information visit http://www.sironabiochem.com.

Sirona Biochem cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise. Actual results, performance or achievement could differ materially from those expressed in, or implied by, Sirona Biochem's forward-looking statements due to the risks and uncertainties inherent in Sirona Biochem's business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Sirona Biochem does not assume any obligation to update any forward-looking statements except as required by law.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

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Sirona Biochem Appoints Three Chemistry Experts to Subsidiary Scientific Advisory Board

Research and Markets: Future German Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and …

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/64caec/future_german_clin) has announced the addition of the "Future German Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and Business Expansion Strategies" report to their offering.

This report presents a comprehensive analysis of the German clinical chemistry and immunodiagnostics markets, including:

Major issues pertaining to the German clinical chemistry and immunodiagnostic laboratory practice, as well as key economic, regulatory, demographic, social and technological trends with significant market impact during the next ten years. Five- and ten-year volume and sales forecasts for over 100 clinical chemistry, TDM, endocrine, cancer, immunoprotein and abused drug assays performed in German hospitals, commercial laboratories, and physician offices, including controls, calibrators and consumables. Five- and ten-year volume forecasts for serum, whole blood, plasma, CFS, urine and other specimens. Five- and ten-year reagent and instrument sales forecasts. Review of current instrumentation technologies, and a feature comparison of 50 high-, medium-, and low-volume/POC analyzers. Sales and market shares of leading reagent and instrument suppliers. Review of current and emerging technologies and their potential market applications Product development opportunities for clinical chemistry and immunodiagnostic instruments and consumables. Profiles of 25 current and emerging suppliers, including their sales, market shares, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies. Market penetration strategies, entry barriers and risk.

The report contains 578 pages and 119 tables.

For more information visit http://www.researchandmarkets.com/research/64caec/future_german_clin

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Research and Markets: Future German Clinical Chemistry and Immunodiagnostics Markets: Growth Opportunities and ...

Google tool helps in chemistry work

Published: Feb. 14, 2012 at 2:57 PM

PULLMAN, Wash., Feb. 14 (UPI) -- A U.S. researcher says technology Google uses to rank trillions of Web pages can help scientists study how molecules are shaped and organized.

Aurora Clark, a professor of chemistry at Washington State University, has adapted Google's PageRank software to create moleculaRnetworks, software to help determine molecular shapes and chemical reactions without the expense, logistics and occasional danger of lab experiments, a WSU release reported Monday.

Google's PageRank software uses a mathematical algorithm to measure and rank the relevance of various Web pages to a user's search, and Clark and her colleagues realized interactions between molecules are a lot like links between Web pages; some links between some molecules will be stronger and more likely than others.

"What's most cool about this work is we can take technology from a totally separate realm of science, computer science, and apply it to understanding our natural world," Clark said.

Just as PageRank is effective at looking at massive amounts of Web data at once, moleculeRnetworks can quickly characterize the interactions of millions of molecules and help researchers predict how various chemicals will react with one another, the researchers said.

"Computational chemistry is becoming the third leg in the stool of chemistry," the other two being experimental and analytical chemistry, Clark said.

"You can call it the ultimate green chemistry. We don't produce any waste. No one gets exposed to anything harmful."

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Google tool helps in chemistry work

It’s the chemistry: Love makes the brain stay strong, scientist says

OTTAWA — Whoever said people in love have good chemistry hit the bull’s-eye without even knowing the whole story.

At Carleton University, neuroscientist Hymie Anisman is opening up the brain’s secrets to show how the chemicals of love (and friendship) make us healthier.

The mere physical presence of someone you trust can support you at stressful times, Anisman says.

“Under most conditions, social support is very, very effective.

“And in a love relationship, (this protection) will be stronger. You’re counting on that person you love to be supportive.”

Love helps our brains remain healthy. But why does it work?

More and more, the scientific investigation of love is turning to a human hormone called oxytocin. It’s involved in everything from bonding with a newborn baby to adult love and friendship, and even simple trust.

Anisman has a Canada Research Chair in neuroscience, and one of his major areas of study is stress.

“We also know that when oxytocin levels are high, we’re less responsive to stressors,” he said. The hormone helps us build social networks and support, and also to cope with stresses. The stress is still there, but we deal with it better.

“So in a nice relationship, you have the oxytocin that’s elevated as part of the love that a person has for another (person). But also, above and beyond these affects of oxytocin, social support is an incredible way of dealing with stress.”

Having a loved one nearby distracts us from problems. It helps us find solutions by asking for help. Even when all that fails, it helps us vent: “Yell, scream, cry, whatever, but get it out. Even if the problem isn’t solved, sometimes venting and praying are all you’ve got left.”

In the long run, he says, having social support from friends or lovers prevents overload on the brain circuits that can result in mental illness such as depression.

“Love is important for all ages, especially if you’re elderly.”

While humans have know for thousands of years that love and simple affection are helpful, the research world has been buzzing with new discoveries related to oxytocin for the past few years.

Now research is focusing on whether the hormone can be given as an inhaled drug to help people reduce social anxiety — to mimic the support of friends.

When that news became public, marketers were quick to offer inhalers on the Internet. But the small print showed they contain no oxytocin, as this isn’t approved for commercial use.

Anisman’s work is funded by the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council.

© Copyright (c) The Ottawa Citizen

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It’s the chemistry: Love makes the brain stay strong, scientist says

Chemistry teachers: Request a free chemistry activity kit from ACS

The following is an e-mail I received from the ACS Kids & Chemistry Program Manager. I’m re-posting it here to spread the word. If you know any chemistry school teachers who might benefit from this program, please forward them the relevant info.

With the support of a grant from the National Science Foundation and the National Institutes of Health, the American Chemical Society has developed a science activity kit for teachers to use with their students. This kit, titled Chemistry: Investigating your World, is being mailed to teachers who request it and meet the following criteria:

•               They plan to use the kit with a minimum of twelve 4th-8th grade students.
•               They request that the kit be sent to a school address within the continental United States.

Do you know a teacher who should know about this free chemistry kit?

If so, please forward the information below.

Request a FREE Science Activity Kit to celebrate the International Year of Chemistry 2011!

Although it’s now 2012, Chemistry: Investigating Your World kits are still available.  The kit is designed with enough materials for multiple classes of 12 to 32 students, working in groups of 4. The activities, reading level, and content are appropriate for students in fourth through eighth grades.

Request a kit at www.acs.org/iyckit.

Using the lessons in the kit, students will see demonstrations and do hands-on activities while investigating clues of chemical change, including:

·         Production of a gas
·         Formation of a precipitate
·         Color Change
·         Change in temperature

Check out the four lessons to find out how meeting scientists around the world, investigating clues of chemical change, and real-life applications make learning chemistry relevant and fun. Then be sure to request your free kit as soon as possible. Supplies are limited!

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Chemistry teachers: Request a free chemistry activity kit from ACS

Pacific Biosciences Releases Next Generation Chemistry and Software for PacBio® RS DNA Sequencing System

MENLO PARK, Calif.--(BUSINESS WIRE)--

Pacific Biosciences of California, Inc. (NASDAQ: PACB - News), provider of Single Molecule Real Time (SMRT®) sequencing products, today announced it has released a major upgrade to its PacBio®RS system, referred to as “C2”, including new chemistry, enhanced SMRT Cells and upgraded software, which together provide customers with significant performance increases for DNA sequencing. The company and numerous customers will discuss their progress with the platform through a total of 50 presentations and posters at the 2012 Advances in Genome Biology & Technology (AGBT) meeting this week in Marco Island, Fla.

The PacBio RS is a revolutionary DNA sequencing system that reveals new biological insights by incorporating novel, single molecule sequencing techniques, advanced analytics, and long read lengths. Compared with the C1 versions launched with the system in April 2011, the PacBio C2 chemistry and software provide approximately:

2x increase in average read length; 3-4x improvement in mappable data per SMRT Cell; 50-80% reduction in input DNA required; and Consensus accuracy of Q50 (99.999%) at substantially lower coverage.

“The changes we’ve made with this upgrade enable significant performance increases and lay the foundation for ongoing enhancements to the PacBio RS,” said Mike Hunkapiller, Ph.D., Chairman and CEO of Pacific Biosciences. “We’re very proud of how far we’ve come in the nine months since we first released the product commercially, and even more proud of our customers’ achievements, many of which will be highlighted this week at AGBT.”

The Wellcome Trust Sanger Institute and The Institute for Genome Sciences (IGS) at the University of Maryland School of Medicine are among the institutions that had early access to a preliminary version of the new chemistry.

“The Sanger Institute has seen significant improvements in performance compared to C1, enhancing our research projects in the areas of de novo genome assembly, sequencing through repetitive elements, enabling coverage of regions with extreme base composition, and improving genome assemblies,” said Harold Swerdlow, Ph.D., Head of Research and Development at the Wellcome Trust Sanger Institute.

Luke Tallon, Scientific Director of the Genomics Resource Center at IGS added: “Early access to the new chemistry has resulted in significantly improved read lengths compared to the original C1 chemistry. These longer reads have enhanced our de novo genome assembly of microbial genomes when combined with short-read data. The longer read lengths have also increased our ability to generate higher-accuracy circular consensus reads.”

The latest generation of SMRT Cells is more robust due to an improved manufacturing process, and the PacBio RS software has been enhanced for improved reliability and greater performance. To date, Pacific Biosciences has developed two whole product solutions that leverage the capabilities of the PacBio RS system to uniquely enable key customer applications: 1) de novo whole genome assembly and 2) targeted sequencing. As an example, the SMRT Analysis software incorporates The Genome Analysis Toolkit (GATK) developed by the Broad Institute. This provides a streamlined pipeline for variant analysis for targeted sequencing.

This week’s AGBT conference will feature a total of 35 presentations and posters from PacBio customers, largely highlighting the two key applications for the system. Scientists from PacBio will also present a total of 15 presentations and posters about the technology. Details are available at http://www.pacb.com/agbt2012.

For more information about Pacific Biosciences, please visit http://www.pacb.com. You can also follow the company on Twitter http://www.twitter.com/pacbio.

About Pacific Biosciences, Inc.

Pacific Biosciences’ mission is to transform the way humankind acquires, processes and interprets data from living systems through the design, development and commercialization of innovative tools for biological research. The company has developed a novel approach to studying the synthesis and regulation of DNA, RNA and proteins. Combining recent advances in nanofabrication, biochemistry, molecular biology, surface chemistry and optics, Pacific Biosciences has created a powerful technology platform called single molecule, real-time, or SMRT®, technology. SMRT technology enables real-time analysis of biomolecules with single molecule resolution, which has the potential to transform the understanding of biological systems by providing a window into these systems that has not previously been open for scientific study.

Forward-Looking Statements

This press release contains forward-looking statements. Forward-looking statements may contain words such as "believe," "may," "estimate," "anticipate," "continue," "intend," "expect," "plan," the negative of these terms, or other similar expressions, and include the assumptions that underlie such statements. Such statements include, but are not limited to, statements regarding the Company’s SMRT technology. These statements are subject to known and unknown risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements, including but not limited to risks discussed from time to time in documents Pacific Biosciences of California, Inc. has filed with the Securities and Exchange Commission, including the risks identified under the section captioned "Risk Factors" in its recently filed Quarterly Report on Form 10-Q. All forward-looking statements are based on estimates, projections and assumptions as of the date hereof. Pacific Biosciences undertakes no obligation to update any forward-looking statements.

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Pacific Biosciences Releases Next Generation Chemistry and Software for PacBio® RS DNA Sequencing System

Molecular carpet: Startling results in synthetic chemistry

ScienceDaily (Feb. 13, 2012) — Swiss scientists have created a minor sensation in synthetic chemistry. The team of scientists from ETH Zurich and Empa, the Swiss Federal Laboratories for Materials Science and Technology, succeeded for the first time in producing regularly ordered planar polymers that form a kind of "molecular carpet" on a nanometer scale.

Back in 1920 at ETH Zurich, the chemist Hermann Staudinger postulated the existence of macromolecules consisting of many identical modules strung together like a chain. His concept was initially greeted with mockery and incomprehension from his fellow chemists. But Staudinger was to be proved right (and eventually even awarded the Nobel Prize in Chemistry in 1953): today the macromolecules described as polymers are known as plastics, and by 1950 one kilogram of them was already being produced per capita worldwide. Today, more than ninety years after Staudinger's discovery about 150 million tons of plastics are manufactured every year -- a gigantic industry delivering products that our daily lives can hardly do without. A research group led by ETH Zurich scientists A. Dieter Schlüter and Junji Sakamoto has now succeeded in making a decisive breakthrough in the synthetic chemistry of polymers: they have for the first time created two-dimensional polymers.

Polymers are formed when small single molecules known as monomers join together by chemical reactions like the links of a chain to form high molecular weight substances. The question remained as to whether polymers can only polymerize linearly, i.e. in one dimension. Although graphene counts as a naturally occurring representative of a two-dimensional polymer -- planar layers of carbon with a honeycomb-like pattern -- it cannot be synthesized in a controlled way. In order to develop a synthetic chemistry that generates two-dimensional molecules the ETH chemists had to first and foremost create oligofunctional monomers in such a way that they join together purely two-dimensionally instead of linearly or even three-dimensionally. Polymers of this kind must have three or more covalent bonds between the regularly repeating units. The scientists had to find out which bonding chemistry and environment was most suitable for producing this kind of "molecular carpet."

Light plus special building blocks equal a "molecular carpet"

They decided to do the synthesis in a single crystal, i.e. a crystal with a homogeneous layer lattice. PhD student Patrick Kissel successfully used this to crystallize special monomers in layered hexagonal single crystals. The monomers he generated are photochemically sensitive molecules, for which such an arrangement is energetically optimum. When irradiated with light with a wavelength of 470 nanometers, the monomers polymerized in all the layers of the crystal. To separate the individual layers from one another the researchers boiled the crystal in a suitable solvent. Each layer represents a two-dimensional polymer.

The fact that the team really had succeeded in producing sheet-like polymers with regular structures was shown by special studies in a transmission electron microscope (TEM) carried out by Empa researcher Rolf Erni and Marta Rossell from ETH Zurich (who meanwhile is also working at Empa's Electron Microscopy Center). "These two-dimensional polymers are extremely sensitive towards irradiation. It's really tricky to not destroy their structure during the TEM measurements, which made the analyses a real tough nut to crack," says Erni. Diffraction experiments at minus 196oC -- the condensation point of nitrogen -- and high-resolution images at a low electron dose allowed the Empa scientists to eventually provide proof that the cross-linked molecules indeed exhibit a regular two-dimensional structure.

Potential application: a molecular sieve

The polymerization method that was developed is so gentle that all the monomer's functional groups are also preserved at defined positions in the polymer. Says Sakamoto, "Our synthetically manufactured polymers are not conductive like graphene, but on the other hand we would be able to use them for example to filter the tiniest molecules." In fact in the regularly arranged polymers there are small defined holes with a diameter in the sub-nanometer range. Moreover, tiny hexagons in the polymers, formed by benzene rings with three ester groups, can be removed by a simple hydrolytic process. This would form a "sieve" with an ordered structure suitable for the selective filtration of molecules.

However, before the researchers can think about practical applications, the task now is to characterize the material's properties. First of all they must find a way to produce larger amounts and even larger sheet sizes. The size of the crystals is currently only 50 micrometers. Sakamoto stresses that "those, however, are already enormous degrees of polymerization at a molecular level."

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The above story is reprinted from materials provided by Empa (Swiss Federal Laboratories for Materials Science and Technology), via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Patrick Kissel, Rolf Erni, W. Bernd Schweizer, Marta D. Rossell, Benjamin T. King, Thomas Bauer, Stephan Götzinger, A. Dieter Schlüter, Junji Sakamoto. A two-dimensional polymer prepared by organic synthesis. Nature Chemistry, 2012; DOI: 10.1038/nchem.1265

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

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Molecular carpet: Startling results in synthetic chemistry

Love: compatibility, chemistry part of it, but communication is the key

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Love: compatibility, chemistry part of it, but communication is the key

The Chemistry Club enlist expert trainers for master classes

The Chemistry Club, a leading independent group serving the technology sector, has today announced they will run a series of networking master classes. The course is set to launch later this year and has been co-created with leading industry trainers.

London (PRWEB UK) 9 February 2012

The one day Master Classes are aimed at senior executives and will help participants improve their networking skills. Taking the company’s founders own experiences in the networking field and with the help of specialist trainers, the company has created a thorough hands-on programme.

The Chemistry Club aims to cover every aspect of face-to-face networking as well as creating a simulated networking event to help delegates practice their new found skills. The master class will cover a wide range of topics including; learning how to prepare for events, combating nervousness, developing confidence in your ability to connect with people you don’t know, and how to start, sustain and finish conversations. Understanding how to make a lasting impression, how to present information about yourself and improving your self-projection will also be covered.

The master class will cost £1100 + VAT and to ensure all attendees gain maximum value from the programme classes sizes are kept to a minimum. Every individual who attends the class will receive a personal reference toolkit providing comprehensive networking information to refer to after the course.

About The Chemistry Club

The Chemistry Club is a leading group serving the technology sector. The company was established in 1999 and holds a series of special briefings, business-to-business events, executive coaching and networking master classes in the Central London area. The business run by Mark Simon is known for its networking events which have enabled people to meet and share their thoughts and experiences in a neutral environment.

###

Ross Hall
FTI Consulting
020 7269 9334
Email Information

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The Chemistry Club enlist expert trainers for master classes

For Newman, good grade in chemistry difficult to maintain

Ryan Newman learned an awful lot about chemistry at Purdue. But the kind of chemistry that can make the minute differences between winning and losing a Sprint Cup race? That can't be found in any textbook that Newman owns.

Case in point: Teammate Tony Stewart was so frustrated with his performance heading into the 2011 Chase that he felt undeserving of a spot in it. But with victories at Chicagoland and New Hampshire, suddenly the chemistry between Stewart and crew chief Darian Grubb changed dramatically.

2011 statistics Newman's Chase differential First 26 Chase Wins 1 0 Top-fives 8 1 Top-10s 13 4 Avg. start 11.9 13.2 Avg. finish 13.1 18.4

And Newman is at a loss to explain it.

"If you look at Tony and Darian's relationship before the Chase, during the Chase and after the Chase, you would scratch your hair until you have no hair," Newman said during NASCAR's preseason media tour. "How that worked? I don't know. I don't know that it was supposed to, but it did.

"It's difficult from my perspective, when you have a great relationship with a guy like Tony Gibson, and all of a sudden, our performance falls down during the Chase. And these two guys -- who were struggling -- skyrocketed to the top in the first two races. It was like, 'What are we doing right that's wrong?'"

Newman points to those two races as not only the turning point in Stewart's season, but his own as well. Newman had recorded six top-10 finishes over a nine-race stretch heading into the Chase, and felt like he had as much momentum as any of the championship contenders.

But as much as the light bulb seemed to turn on for Stewart and Grubb, Newman said he and crew chief Gibson quickly found themselves groping in the dark for answers after the first two Chase races.

"I guess some of our struggles in a roundabout way were due to [Stewart's] success," Newman said. "He wins the first race in the Chase [on fuel mileage] after not winning any, and we run out of fuel and finish eighth. We go to the next race, win the pole, lead a bunch of laps and finish [25th], and he wins the race."

"That was the extra weight on our shoulders that kind of squashed us."

After missing the Chase in 2010, making it in 2011 should have left everyone on the No. 39 Chevrolet team with a positive feeling. But watching Stewart win the title -- while himself finishing a distant 10th in the points -- left Newman with mixed feelings.

When you have the opportunity to capitalize on your success and don't close the deal -- especially when your teammate does -- it can leave a bitter aftertaste.

"We definitely failed, from a team standpoint, in those 10 races," Newman said. "Our chemistry dissolved. We have to control that better. That's one of the things we have to fix for 2012, hands down.

"I feel like we've had some opportunities that have gotten away from us. I won't say we've given races away but we should have been in Victory Lane more often than we have been. Those are the things we need to fix.

"Those things go hand in hand," Newman said. "When you can't fix those things and you know that you should -- and are capable of doing it but you haven't -- that makes it really tough to swallow."

The goal for Newman this season is to try to regain that chemistry. But saying it and doing it are two separate things.

"Chemistry, you can't make it happen," Newman said. "It either happens or it doesn't. Going back to 2009, you look at Tony Stewart's first 26 races -- he was the hands-down favorite to win the Chase and he didn't. He clobbered everybody and didn't win. But he has a horrible first 26 [in 2011] and wins. Same guy, same people. There's something there and I don't know what it is."

What it isn't is a rift between Newman and Gibson. If anything, Newman said that relationship only grew stronger from the adversity the two faced at the end of last season.

Newman admitted the final 10 races last year "were a struggle." But he remains committed to making the changes necessary to make the relationship with Gibson work.

"Relationships in general are like marriages," Newman said. "We argue about the simple things that don't matter, because the big things that do matter -- we've already agreed on. That's why we got married. And that's the situation with myself and Tony Gibson.

"I understand that he knows what he's doing as a crew chief. I know what I'm doing as a driver. We understand what our goals are. But it might be the simple things -- the way he works something or the way he describes it in reference to what he's had in the past -- and those are the things, the small humps, you have to get through."

It there was a magic formula for team chemistry -- a list of properties that could guarantee success -- Newman would be the first in line to test the results. Until then, it's more a matter of field study rather than classroom lab work.

"I still say it's chemistry," Newman said. "I don't know, and that's the real thing that's so amazing.

"It'll be interesting to see how the first five, 10 races go with Tony and [his new crew chief, Steve Addington] versus me and Tony. ... Chad Knaus and Jimmie Johnson can talk about it a different way, and Jeff Gordon and Alan Gustafson can talk about it a different way. It all changes."

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For Newman, good grade in chemistry difficult to maintain

Mailbag 2/11: What’s With UConn’s ‘Chemistry?’

 

Q: Your thoughts on the teams lack of chemistry?  It seems to me that so so-called leader Shabazz is very much like Jerome Dyson was.  That team was pulled apart from within and it appears it is happening with this group.

Paul Ippedio

Saco, Me. (formerly of Manchester)

A: Hi  Paul. This comes up a lot, in fact Kevin Nathan and I talked a lot about chemistry on WTIC SportsTalk on Friday. I didn’t cover the Jerome Dyson teams so I can’t speak to that comparison.

I don’t think this team is being pulled apart from within, though, at least not from what I can see. There are different types of chemistry. One is working together, getting along, etc., and I think this team still has that. The other is the meshing of skill sets, and that’s where I think the problem is. Certain guys do certain things well, others not so well, and it doesn’t quite fit together. For instance, Alex Oriakhi is good at certain things that he may not be able to do with Andre Drummond also on the court. The team likes to run, but guys don’t take and make good shots in transition. Shabazz Napier likes to throw certain types of passes that guys can’t catch. … And so on. It’s a reason, I suppose, we have seen so many different combinations. This type of chemistry is much harder to fix, but it does happen sometimes. At some point things could just click, fall into place, and the chemistry on the court and bench will look a lot different. But 23 games into the season, it’s getting late to expect that to happen. At Syracuse today, we’ll see.

 

 

 

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Mailbag 2/11: What’s With UConn’s ‘Chemistry?’