Podcast 11 Athens Part 5


Shownotes

Merry christmas and happy holidays to all

Lu177-DOTA therapy for SS-2 tumors
Dr Kwekkeboom, Rotterdam, Netherlands

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Episode 12 Cardiac Nuclear Medicine in the UK


Show notes
Two interviews focusing on cardiac disease in the UK
With Professor Richard Underwood
And Dr Eric Lim

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Please pass on information about this podcast to your colleagues and to your CPD provider.
Remember you can get the podcast but going to itunes and entering the search term nuclear medicine best the way to subscribe is via this link

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Podcast 10 Athens part 4


Shownotes

News
Alexander Litvinenko poisoned with polonium-210

Interviews from Athens EANM

Nuclear imaging in the assessment of the results of (cardiovascular) therapy
Dr F. Bengel, Baltimore, USA
Stem Cell therapy (this is now being done in the Netherlands, good paper from there also)
Reporter gene imaging
Anti-arrhythmia imaging Plaque imaging and cell wall imaging

V/Q SPECT reporting 4696 cases
M Bajc, Lund, Sweden

1% non-diagnostic or intermediate probability or contraindicated scan vs 27% + for CTPA
The co-registered VQ quotient
Total scans done in 25 mins
Needs modeled reconstruction (3D flash/Astonish)
Needs technigas
These patient numbers dwarf pioped or wells!
V/Q SPECT great for other lung disease pneumonia etc Other paper

You can get text of the podcasts from
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Podcast 9 Athens part 3 and news


Shownotes

Rods pulse podcast
?http://www.rodspulsepodcast.com/

Hepatitis C Virus Infections From a Contaminated Radiopharmaceutical Used in Myocardial Perfusion Studies
Priti R. Patel, MD Etal
JAMA. 2006;296:2005-2011.

Amifostine can reduce toxicity of targeted radionuclide therapy without affecting anti-tumour effect
F.Forrer Rotterdam
Its an old drug used routinely for radiotherapy
Amifostine has been used for protecting salivary glands
It makes a dramatic effect in reducing kidney dose in Lu177-DOTA
Thus doses can be safely increased and increasing chance of complete remission

SPECT/CT
Dale Bailey, Sydney, Australia
How to make a Home made SPECT/CT
He showed how much of an impact this made on reports > 40% much higher than expected
Physicians said “I’ve been confidently giving the wrong reports for 10 years!”

Depression + Anxiety correlation with MPI imaging
Ansari-Gilani, Tehran, Iran
Depression has been shown as a risk factor for cardiac disease
Patients with a high BDI score had a statistically significant correlation with the perfusion difference score
The effect is stronger with 3 vessel disease and also with depression than anxiety but both had significant P values
Interestingly it was also true before patients had a diagnosis of CAD

The music was by a greek band called
FadeOut and the song was sanctuary
http://music.podshow.com/music/listeners/artistdetails.php?BandHash=8716094d92e8f0209c8b8b34f7c6d373

You can get text of the podcasts from
http://www.podzinger.com/results.jsp?s=PZSID_pod1_3_2_0008;The+Nuclear+Medicine+and+Molecular+Medicine+Podcast&start=0&num=10&col=en-all-pod_safe-ep&filter=0&sname=&mc=en-all&il=en


Please pass on information about this podcast to your collegues and to your CPD provider.
Remember you can get the podcast but going to itunes and entering the search term nuclear medicine best the way to subscribe is via this link

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2. Enter the phone number 207-099-2527
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3. Record your message, don?t worry it wont go straight into the podcast unless you ask me too.
Please leave your name and email address in your message so I can get back to you.
You can email me at rob@nuccast.com
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Send Me A Message
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Europeans Announce Pioneering Surgery

The New York Times reports today that European physicians have successfully transplanted a human windpipe using the recipient's own bone marrow stem cells to reline a donor trachea, thus preventing its rejection by her immune system. Using a new technique developed in Milan, physicians incubated stem cells removed from the patient's bone marrow, growing them into "a large population" which was then used to "seed" the donated windpipe. This is yet another interesting use of autologous stem cells, demonstrating their quickening pace of use in regenerative medicine.

US FDA allows first test of human stem cell therapy

WASHINGTON, Jan 23 (Reuters) - The U.S. Food and Drug Administration has cleared the way for the first trial to see if human embryonic stem cells can treat people safely, a company involved in the controversial research on Friday. Geron Corp (GERN.O: Quote, Profile, Research), a California biotechnology company, said it plans a clinical trial to try to use the stem cells to regrow nerve tissue in patients with crushed, but not severed, spinal cords.

Not All Stem Cells Are the Same

This week the Obama administration has given embryonic stem cell researchers what they've been seeking: the potential to receive funding from the National Institutes of Health (NIH). Here's the irony: now that the funding restrictions are lifted, embryonic stem cells may not be the primary focus of stem cell research anyway.

Limb-Saving Trial Shows Promise

Autologous use of stem cells (in this case, from bone marrow) show promising results and is noteworthy because the treatment is cheaper, safer and less invasive than other alternatives (angioplasty or bypass) for peripheral artery disease. Medicare is said to be looking into the treatment.

Strokes Can Affect Children, Too – A unique program at UCSF is treating children who have suffered strokes

The article highlights the frequency of stroke in children and calls attention to the potential consequences of neurological deficit. The story reinforces the significance of the research being conducted at Duke University using a childs own cord stem cells to help heal the damage caused by stroke. Chloe Levine is one example of a child who has experienced positive changes since her infusion.

Women health heart attack

Women are in as much danger when it comes to heart disease as men, although a full half of all American women don't know that fact. TheraVitae, creators of VesCell for Heart Disease adult stem cell therapy, offers these women health heart attacks facts to help make sense of the very real heart failure epidemic that affects women, too.

Rest Pain Leg | VesCell adult stem cells for peripheral artery disease

Rest pain in one's leg is one of the symptoms of peripheral artery disease (PAD), a serious blockage of circulation that can lead to the loss of limb often related to diabetes. A treatment known as VesCell PAD uses the adult patient's own stem cells to treat the limb suffering the effects of PAD. This painless stem cell therapy was chosen by a middle-aged American diabetic woman who traveled to Thailand in the summer of 2008 in the hopes of avoiding amputation.