Nanotechnology: Smiles all round

A smile can say more than a thousand words, the saying goes. Orthodontics can help improve the appearance and position of people's teeth and jawbones, for better functioning teeth and more attractive smiles. In recent years, dental correction orthodontics has used braces made from clear plastic polymer to good effect, but now they are hoping to improve on this with help from nanotechnology. A Spanish university has patented a breakthrough new process, producing smiles all round.

Orthodontic treatment is carried out using braces, which generally fall into two broad categories: removable braces (or retainers), and fixed braces (or train tracks). They may be made of metal, white porcelain or clear plastic. Braces made from a clear plastic polymer have a better aesthetics when compared to metal braces, but they do come with their own set of problems, such as wear and tear within the mouth. This is where advances in nanotechnology could provide solutions.

'We were estimating the friction between teeth and the brackets [braces], and it occurred to us that nanotechnology might be of use to help us resolve this issue,' remarked Juan Baselga, head of the Universidad Carlos III de Madrid (UC3M) Polymers and Composite Group. The solution that they came up with is to use very hard alumina nanoparticles and spread them evenly in the polysulfone, the polymer mould that the company CEOSA-Euroortodoncia uses in the industrial production of the braces.

The researchers from UC3M, together with a private company, have patented a new process and have produced a new material that increases the mechanical as well as the friction resistance, thereby maintaining the braces' transparency. 'We have been able to develop a more rigid material with this technology which has a clearly improved friction resistance, thus helping to withstand the wear and tear produced by the teeth or by chewing,' Professor Baselga explained. 'In addition, it is biocompatible, which is essential for something that is going to be used in the mouth, and complies with European requirements for products which are in contact with food.'

This innovation allows nanoparticles to be incorporated and evenly dispersed in a polymer mould in a very low proportion. After this process - based on green chemical techniques - is carried out by UC3M researchers, the particles are dispersed in the polymer through micro-extrusion and microinjection techniques, and are finally mixed to produce the final piece.

'We measure out the plastic since the minimum that a normal machine can inject is 15 grams, whereas our pieces weigh .06 grams ... it would be akin to injecting insulin with a horse syringe,' explained company Director, Alberto Cervera. 'And with the technology we are using, micro-extrusion and the micro-injection, we are capable of controlling these minuscule quantities of material with the utmost precision,' he added.

It is worth noting that the relationship between UC3M and CEOSA-Euroortodoncia takes advantage of the synergy between the public and private sector. 'We are a small to medium-sized enterprise and we get support from the University to produce a first-rate product, which is then advantageous in the agreements which we have had for a decade in the form of end-of-degree-projects, doctorial theses and joint research programs within the European Union and in the Madrid Autonomous Community, for example,' Alberto Cervera elaborated. 'We learn a lot from this collaboration,' continued Juan Baselga, 'because this company presented us with real problems that they face in their industrial area and they open up their laboratories to our needs.'

According to the researchers, these new materials, nano-reinforced plastics, can have applications in fields other than orthodontics. In particular, polysulfone is of interest in the biohealth field in the development of medical/surgical equipment: its biocompatibility means it can be used to improve rigidity and friction resistance. Furthermore, it has potential applications in the auto industry and in the area of safety, such as the development of a new visor for firefighters, for example.

More information: http://www.dmceosa.com/

Provided by CORDIS

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Nanotechnology: Smiles all round

Ferris State's new Grand Rapids laboratory aims to fill skills gap in Michigan's medical industry

GRAND RAPIDS, MI -- Inside Ferris State Universitys newly renovated molecular diagnostics lab, students are learning the skills that administrators say will make them a perfect fit for clinical laboratories in West Michigan and beyond.

Located on the campus of Grand Rapids Community College, students at the lab are learning the techniques needed to use molecular technology to screen patients before organ transplants, detect genetic disorders and infectious diseases, and determine therapy for genetic disorders.

Its administrators hope that Ferris students will master the techniques and fill a demand expressed by hospitals and medical employers around the country for clinical laboratory workers, trained in the burgeoning field of molecular medicine, Ferris said.

Weve heard from people within the field that their labs are looking for students with this certification and who have an education in molecular diagnostics, said Jonathan Karnes, the programs coordinator. Theres a need in the job market for students with this type of degree.

On Wednesday, Nov. 28, students enrolled in Ferris molecular program were preparing for an experiment in which they would examine their own DNA to find out whether they had they had a certain type of gene known as the Alu gene.

Unlike other types of clinical laboratory testing, molecular diagnostics goes beyond the cellular level, and instead checks for ailments on the molecular level, looking for clues in areas such as DNA, Karnes said.

Adam Placer, a senior at Ferris, compared it to solving a puzzle.

I like to trouble shoot, Placer said, and I like to solve problems, and ultimately I like to help people, which is why were here. Related: Ferris State University looks to better serve Latino students Ferris lab, located in GRCCs Applied Technology Center, was completed shortly before fall semester. The university spent $1.4 million to renovate the 3,200-square-foot space and buy equipment. Ferris molecular diagnostics program was created in fall 2011, and its first six students are expected to graduate this spring.

The first three years of the program take place at Ferris main campus in Big Rapids. Students take their fourth year at Ferris new lab in Grand Rapids.

Karnes said the university decided to expand in Grand Rapids because it wanted students to be near the citys Medical Mile. The hope is that students will network and build relationships with medical employers, possibly leading to job offers upon graduation.

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Ferris State's new Grand Rapids laboratory aims to fill skills gap in Michigan's medical industry

Molecular knock-out alleviates Alzheimers symptoms in mice

30.11.2012 - (idw) Deutsches Zentrum fr Neurodegenerative Erkrankungen e.V. (DZNE)

Joint Press Release from the German Center for Neurodegenerative Diseases and the University Medical Center Gttingen

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Gttingen (UMG) have identified an enzyme as a possible target for the treatment of Alzheimers disease. The protein known as HDAC6 impairs transport processes within the nerve cells. The scientists observed only mild symptoms of the disease in mice if the enzyme was not produced. They propose to block its activity in a targeted fashion to treat the disease. Scientists from the DZNE sites in Gttingen and Bonn, the UMG as well as from the US participated in this basic research project on Alzheimers disease. The study is published in "EMBO Molecular Medicine".

The researchers led by Prof. Andr Fischer, Department of Psychiatry and Psychotherapy at the University Medical Center Gottingen and Site Speaker of the DZNE in Gttingen, investigated mice with a modified genetic background. The animals showed behavioural disorders and brain deposits that are typically associated with Alzheimers disease. The researchers went a step further with a group of other animals by removing the genes responsible for the production of the HDAC6 enzyme (histone deacetylase 6). This intervention proved to be effective: while these mice also exhibited the pathological features of Alzheimers disease in the brain, their behaviour was significantly ameliorated. "The animals ability to learn and to find their spatial bearings was relatively normal", says Prof. Fischer. "Their cognitive abilities were fully comparable to those of healthy mice."

Improved cellular traffic

In the researchers view, this effect is at least partly attributable to the fact that important transport processes within the nerve cells are facilitated when the HDAC6 enzyme is not around. This meant in particular that the cells power plants, also known as "mitochondria", can travel to their final destinations. "It is known that in various neurodegenerative diseases cellular transport is no longer functional. The substances that are to be transported along axons are left behind", Fischer says. "Measures which improve trafficking seem to have a positive effect."

Possible target for therapy?

The researchers findings suggest that the HDAC6 enzyme could be a possible target for therapies against Alzheimers disease. However, treatments would require an active substance that can disable the enzyme in a targeted fashion. Unfortunately, the active substances known to date are too unspecific. Prof. Fischer explains that their application resembles a broad-spectrum treatment: "We dont know precisely what is the therapeutic effect of the inhibitors, since they simultaneously block several enzymes from the histone deacetylase family", he says. "And we still dont know enough about how the individual enzymes function".

Original publication: "Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimers disease", Nambirajan Govindarajan, Pooja Rao, Susanne Burkhardt, Farahnaz Sananbenesi, Oliver M. Schlter, Frank Bradke, Jianrong Lu, Andr Fischer, EMBO Molecular Medicine, online at: http://onlinelibrary.wiley.com/doi/10.1002/emmm.201201923/abstract

The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care. It is an institution of the Helmholtz Association of German Research Centres with sites in Berlin, Bonn, Dresden, Gttingen, Magdeburg, Munich, Rostock/Greifswald, Tbingen and Witten. The DZNE cooperates closely with universities, their clinics and other research facilities. Its cooperation partners in Gttingen are the Georg-August-University and the University Medical Center Gttingen. Website: http://www.dzne.de/en function fbs_click() {u=location.href;t=document.title;window.open('http://www.facebook.com/sharer.php?u='+encodeURIComponent(u)+'&t='+encodeURIComponent(t),'sharer','toolbar=0,status=0,width=626,height=436');return false;} html .fb_share_link { padding:2px 0 0 20px; height:16px; background:url(http://static.ak.facebook.com/images/share/facebook_share_icon.gif?6:26981) no-repeat top left; } Share on Facebook

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S7PCauseVideoCongo1 – Video


S7PCauseVideoCongo1
http://www.satoriseven.com Clips from one of our Cause Videos highlighting the needs and improvements in education and medicine in the Democratic Republic of Congo, in partnership with the Presbyterian Church, USA and the Congolese Presbyterian Church. Satori Seven Productions edited the live PowerPoint presentation into a 30 minute video for wider distribution to potential volunteers and donors. Everyone loves a story. Ready to tell yours? Contact us! httpFrom:sheremerickViews:0 0ratingsTime:02:48More inFilm Animation

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Former President George HW Bush hospitalized in Houston for bronchitis – Video


Former President George HW Bush hospitalized in Houston for bronchitis
Former President George HW Bush was in a Houston hospital Thursday for continuing treatment of a lingering cough. Bush, 88, has been in and out of the hospital recently for complications resulting from bronchitis, Methodist Hospital said in a brief statement. The hospital and Bush #39;s spokesman in Houston, Jim McGrath, described Bush as in stable condition and said they expected the former president to be released by the weekend. He #39;s been under hospital care for nearly a week. "If you asked him today, he would tell you he feels good enough to get out this afternoon," McGrath said Thursday. "But the doctors have a different view. He #39;s 88, and they #39;re being extra careful, and understandably so." The former president #39;s illness was described as not life-threatening. "This was never a serious or life-threatening situation," said Dr. Amy Mynderse, an internal medicine specialist in charge of Bush #39;s care. "We simply wanted to prevent the progression of the disease into pneumonia, which is possible in any patient at this age." Bush was treated with antibiotics and steroids, she said in a statement issued by the hospital. Read more: http://www.foxnews.comFrom:Misty De La RosaViews:0 0ratingsTime:02:52More inNews Politics

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Zambia US Alumni Exchange Association_ Dr. EMMANUEL M. MAKASA – Video


Zambia US Alumni Exchange Association_ Dr. EMMANUEL M. MAKASA
Former NASA DEVELOP intern Dr. Emmanuel Makasa, an orthopedic surgeon from Zambia, who served in the DEVELOP program through Marshall Space Flight Center (MSFC) and the University of Alabama at Birmingham (UAB) in the Laboratory of Global Health Observation, has been back serving his country since June 2009. As a Fulbright Scholar, Dr. Makasa earned a Masters in Public Health epidemiology. He continues to work in the public service of Zambia under the Ministry of Health as a Senior Registrar in Orthopedics surgery at the University Teaching Hospital in Lusaka. He also serves as honorary lecturer at the University of Zambia, School of Medicine, and is an ardent researcher who has greatly contributed to local medical publications through the Medical Journal of Zambia since his return. Dr. Makasa has been actively involved in public health outreach activities as co-founder of the non-profit organization Doctors Outreach Care International which provides the scarce volunteer health workers to underserved populations through mobile clinics in partnership with cooperate entities through their cooperate social responsibilities portfolio. He was recently appointed trustee of the Lusaka Orthopedics Research and Education Trust (LORET) under whose FLYSPEC program he constantly volunteers to fly to rural communities countrywide where he performs orthopaedic surgery, conducts clinics and teaching of local health workers being one of only ten orthopedic surgeons in the country. As ...From:usembassyzambiaViews:2 0ratingsTime:01:12More inNonprofits Activism

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818-339-5064 Peter: GetFreeWater… GoAskPete REAL LIFE TESTIMONY. – Video


818-339-5064 Peter: GetFreeWater... GoAskPete REAL LIFE TESTIMONY.
http://www.EvenLowerPrices.com Intubation refers generally to inserting a flexible tube anywhere in the human body, but most people use it specifically to refer to tracheal intubation, which involves putting a down into someone #39;s trachea to secure his or her airway. Intubation is often used in emergency medicine when a patient is having difficulty breathing, and it is also used during surgery to keep the airway open for the delivery of anesthetic drugs and oxygen. In addition, patients on mechanical ventilators will be intubated so that the ventilator can breathe for them. Intubation can be a dangerous procedure when it is not performed properly, and training in intubation is usually quite extensive.To perform a tracheal intubation, a doctor or emergency medical technician ideally uses a laryngoscope, a medical device which is inserted into the mouth to open the jaw. The laryngoscope also lets the doctor clearly see the patient #39;s throat, ensuring that the tube is placed in the correct passage; if an intubation is performed improperly and the tube ends up in the esophagus, the results for the patient can be quite unpleasant and even deadly if not caught in time. An intubation tube is slowly threaded into the throat, with a doctor requesting a smaller or larger size if needed. If the patient is at all conscious, he or she may fight the intubation, since it feels extremely unpleasant. Once the tube is in, it is secured, and it can be attached to a mechanical ventilator, anesthesia ...From:EvenLowerPricescomViews:1829 3ratingsTime:10:33More inNews Politics

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818-339-5064 Peter: GetFreeWater... GoAskPete REAL LIFE TESTIMONY. - Video

Now We Can Share the Ways of Spirit – Video


Now We Can Share the Ways of Spirit
http://www.StarKnowledgeConference.com To order passes or Livestream to Phoenix Star Knowledge Conference http://www.starknowledgeconference.com Chief Golden Light Eagle will host many Chiefs, medicine people, and wisdom keepers at the next Star Knowledge Conference.From:GreenGuerrillasViews:0 0ratingsTime:02:17More inEducation

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Old Crow Medicine Show – Wagon Wheel (ACOUSTIC COVER) – Video


Old Crow Medicine Show - Wagon Wheel (ACOUSTIC COVER)
Second video! I know, its a little overdone, but its still a favorite! And I #39;m sure you #39;ll notice my little cat jumping around in the back. You #39;ll have to excuse him. He has a bad case of curiosity..From:chelseyDOOBZViews:0 0ratingsTime:03:42More inMusic

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Optimising the Performance of the Human Mind: Steve Peters at TEDxYouth@Manchester 2012 – Video


Optimising the Performance of the Human Mind: Steve Peters at TEDxYouth@Manchester 2012
Dr Steve Peters is a Consultant Psychiatrist working full time in Elite Sport. He works with the UK Athletics, British Cycling, Sky Pro Cycling teams and has had involvements with a further twelve Olympic Sports as well as England Rugby and Premier league Football. His career began with teaching Mathematics and then moved on to Medicine. He has worked in the clinical field of Psychiatry for the past twenty years culminating in working at a special hospital with patients who had severe and dangerous personality disorders. Steve has been engaged with Sheffield University as a Senior Clinical Lecturer since 1994 and is also Undergraduate Dean. He holds degrees in Mathematics, Medicine and a Masters Degree in Medical Education, also with postgraduate qualifications in Sports Medicine, Education and Psychiatry. He is a member of the Royal College and is on the question setting board for College Membership exams. He is one of a small team of doctors who assess and grant Therapeutic Use Exemption certificates for UK Sport. His specialist interest is in the working of the human mind and how it can reach optimum performance applied to all walks of life. In thespirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x ...From:TEDxYouthViews:0 0ratingsTime:13:17More inScience Technology

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Wilderness & Mountain Medicine Winter Conference with Altitude

The Wilderness Medical Society to host the 21st Wilderness & Mountain Medicine Conference in Park City, Utah, February 15-20, 2013, at the Canyon Resort in Park City, Utah. This conference brings together altitude, avalanche, and mountain medicine experts from around the U.S. for a one-of-a-kind medical conference.

Salt Lake City, Utah (PRWEB) November 29, 2012

At this conference, the WMS will continue the exciting new program in association with the University of Utah and the University of Colorado the Diploma in Mountain Medicine(DiMM). This program is designed to train participants in the essentials of mountain medicine and rescue in technical alpine environments. The International Diploma in Mountain Medicine has set the standard over the past 10 years in Europe and other parts of the world for education of doctors, nurses, and medics in mountain medicine and rescue.

Registration is now open and further details regarding conference schedule and faculty can be found on the Society's website.

The Wilderness Medical Society (WMS), a 501(c)3 organization, is the world's leading organization devoted to wilderness medical challenges. Wilderness medicine topics include expedition and disaster medicine, dive medicine, search and rescue, altitude illness, cold- and heat-related illness, wilderness trauma, submersion injuries, envenomation, and wild animal attacks.

Loren Greenway, PhD, CEO Wilderness Medical Society 801-990-2989 Email Information

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Wilderness & Mountain Medicine Winter Conference with Altitude

WHO Pursuing Update on Global Strategy for Traditional Medicine

HONG KONG

The origins of traditional medicine in Asia, Africa and the Americas can be traced back thousands of years. A successful history of traditional disease prevention and treatment has been viewed with skepticism by contemporary scientists. But such views seem to be changing.

The World Health Organization is meeting in Hong Kong as preparations continue to update a global strategy for traditional medicine first outlined in 2001.

One fifth of the worlds population is believed to rely on traditional healthcare. According to WHO figures, 119 countries have developed regulatory frameworks for traditional medicine - or TM.

Dr. Zhang Qi is coordinator of the Geneva-based agency's traditional and complementary medicine unit.

This shows we should recognize the existence and harness the potential of TM [traditional medicine] to contribute to healthcare. We also [need to] ensure the safety, quality and effectiveness of TM for the public," he said.

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WHO Pursuing Update on Global Strategy for Traditional Medicine

When narrative and medicine collide

I have been a physician for 35 years and a literary critic for 14. I have gradually come to understand that the care of the sick is an art form.

Beethoven, Rembrandt, and Henry James created art. Listening to the Razumovsky string quartets, looking at a Rembrandt self-portrait, or reading The Wings of the Dove are also creative acts that transport the listener, the viewer, or reader. One mobilizes ones capacity to perceive, to appreciate, to think about, and to be moved by the music, painting, or novel so as to understand itor, more simply and profoundly, to undergo it. These acts of creative perception summon the witness into complex actions and states of attention. They admit the witness into a state he or she did not inhabit before that act of perception. The dividends of such acts of aesthetic witnessing include some new comprehension of the work itself. The dividends also, inevitably, include the witnesses comprehending themselves in a new way.

For centuries, medicine has looked to philosophy, literature, history, and the visual arts for some sort of nourishment, although it has remained obscure to many exactly why these fields have something to contribute to clinical practice. I see now that the inclusion of the humanities and the arts within clinical training permits an essential development of the aesthetic capacity to behold and to be moved by the presence of another. What occurs in beholding the work of art, I believe, occurs in beholding another person, and certainly in beholding a patient under ones care.

In 1999, I completed a Ph.D. in English at Columbia, and wrote about Henry James under the supervision of professor Steven Marcus. By the time I started graduate school, I was already an associate professor of clinical medicine, seeing patients in the medicine clinic in Presbyterian Hospital uptown. What had driven me to the English department was the happy suspicion that learning how stories are built, how they work, and what to do with them would make me a better doctor. I think it has. As I brought my humanities studies into the medical school at Columbia, the phrase narrative medicine came to mind. I leapt happily to it, for it seemed a much better name for what was otherwise called humanities and medicine or, worse, medical humanities. The name seemed to me to propose that medicine is saturated to its core with narrativityin its teaching, its research, and its practice.

By 2002, I invited several University faculty members to join me in a National Endowment for the Humanities project to figure out why narrative training might benefit clinicians. Maura Spiegel from the English department, David Plante from creative writing, Sayantani DasGupta from pediatrics, Eric Marcus from the Columbia University Center for Psychoanalytic Training and Research, Craig Irvine (a philosopher on staff in family medicine), and I taught one another about our own disciplines and passions to conceptualize why narrative theory, texts, and methods might enter into and improve clinical practice. We realized that literary and aesthetic study might let doctors see multiple perspectives, might equip them to represent and therefore perceive the complex events of illness, and might attune them to the beautiful, unusual, or awesome in their work. The curiosities developed by close reading and creative writing might dispose the doctor or medical student to attend closely to the situation of a patient in his or her care. We thought, perhaps, that doctors might be more ready to behold the mysteries present whenever a patient sits down in the clinical office to give an account of the self. We wanted to provide these doctors and students with the wherewithal to attend to, to perceive, to represent, and ultimately to make contact with the patients in therapeutic affiliation. The narrator in Wings of the Dove describes what the doctor, Sir Luke Strett, does on first meeting his dying patient Milly Theale: So crystal clear the great empty cup of attention that he set between them on the table. That was the attention we sought to develop for our doctors and nurses and social workers, the attention any sick person needs. Since then, the program has grown exponentially: narrative medicine training programs throughout the medical center, a Master of Science in narrative medicine degree program at Columbia, required courses at the medical school, international narrative medicine training workshops, outcomes research projects, and the International Network of Narrative Medicine to launch next spring.

When the clinician is equipped with narrative capacities to receive the accounts that patients give of themselves, the story is heard, the patient is beheld, the situations narrative world is entered. The participants join by virtue of this entry. The membranes between them become permeable. The doctor is moved by the situation of the patient, moved not just to feeling, but to action. And so narrative medicine begins.

The author is professor of clinical medicine and executive director of the Program in Narrative Medicine at Columbia University College of Physicians and Surgeons. She graduated from Harvard Medical School in 1978 and received a Ph.D in Columbias English department in 1999.

To respond to this professor column, or to submit an op-ed, contact opinion@columbiaspectator.com.

Created: Thursday 29 November 2012 07:24pm

Updated: Friday 30 November 2012 12:51am

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When narrative and medicine collide

Sarcoma Alliance: More Alternative Medicine Goes Mainstream

The national nonprofit for people with the rare cancer has changed its page on complementary and alternative medicine to ensure reliability.

Boston, MA (PRWEB) November 29, 2012

"Many treatments once considered alternative are now found in large hospitals and cancer centers," says Siegel, a leiomyosarcoma survivor who lives in Tampa. Common ones include acupuncture, massage, reiki, healing touch, chiropractic, guided imagery, meditation, tai chi, qi gong, yoga, herbal medicine, dietary supplements, and art and music therapy.

Alternative medicine refers to treatments that are alternatives to Western medicine, also known as conventional, standard or mainstream medicine, she says. The same treatments may be called complementary or integrative if used in addition to standard medicine.

Calling alternative medicine medicine is kind," says Dr. George Demetri, director of the Center for Sarcoma and Bone Oncology at the Dana-Farber Cancer Institute in Boston. "We need to be careful about how we use language. Show me an alternative medicine that works and Ill show you a medicine that is no longer alternative.

"On the Sarcoma Alliance website, I deleted links to treatments that have not proven helpful," Siegel says. "If people want to get coffee enemas, for example, that's their business. But I'm not going to link to it. Instead, we direct patients to sites that can teach them about safety, research, clinical trials, how to talk to your oncologist, how to pick a CAM practitioner and how to avoid scams. They can search databases alphabetically to learn about particular treatments that interest them."

Kris Carr, author of Crazy Sexy Cancer, is a famous example of a sarcoma patient who has combined choices once considered alternative, such as a vegan diet, with conventional medicine. Carr, who has slow-growing epithelioid hemangioendothelioma, promotes healthy and joyful living, but never says that will cure cancer.

Kris can be misinterpreted, says Demetri, her oncologist. Saying a persons lifestyle causes sarcoma or encourages it to grow sort of falls into blame-the-victim thinking.

Im a huge fan of healthy behavior," he adds, but nobody knows if diet affects sarcoma. If it did, he says, the U.S. might have more cases, considering the way Americans eat. One would also expect to see some cross-cultural differences. Im much more concerned about exposures in the environment, such as radiation and chemicals.

The Alliance, based in Mill Valley, Calif., is a national nonprofit that provides education, guidance and support to people affected by sarcoma. The cancer arises in connective tissue, including muscle and bone. That means it can occur in any part of the body in any age, from newborns on up, Siegel says. There are more than 50 subtypes.

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Sarcoma Alliance: More Alternative Medicine Goes Mainstream