Iran’s auspicious monkey launch

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Iran's president says the Islamic republic has successfully sent a monkey into space for the second time, as part of a program aimed at manned space flight.

Hassan Rouhani's website president.ir said on Saturday the launch of the rocket dubbed Pajohesh, or 'Research' in Farsi, was Iran's first use of liquid fuel.

It said the monkey, named Fargam, or 'Auspicious', was returned to Earth safely.

It did not say when the launch happened or give other details.

Iran frequently claims technological breakthroughs that are impossible to verify independently.

The Islamic republic has said it aimed to send an astronaut into space.

It said it sent a monkey into space in January, reaching a height of 120 kilometres, but one of two official packages of photos of the simian space traveller depicted a different monkey, raising doubts among international observers as to whether the launch was as successful as reported.

The US and its allies worry that technology from the space program could also be used to develop long-range missiles that could potentially be armed with nuclear warheads.

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Iran's auspicious monkey launch

ARTICLE IN PRESS – Nanomedicine

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Unsung Hero: Lollipop man who loves his job come rain or shine

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Unsung Hero: Lollipop man from Chessington who loves his job come rain or shine

5:00am Sunday 12th January 2014 in News By Nazia Dewji, Reporter

A Chessington lollipop man has said not even the dreary English weather gets him down when he is working.

Martin Constable, 37, has been positioned rain or shine at the zebra crossing in Moor Lane serving schoolchildren at Castle Hill Primary School for nearly five years minus a seven-month stint in Leatherhead Road last year.

The council employee who was born and bred in Chessington said he came across the job by luck after an old boss passed on a flyer.

Mr Constable, of Elm Road, said: He could not find anyone that was interested. I turned up for the interview and, as they say, the rest is history. It was a bit of luck.

I love it. I am very lucky because Castle Hill is a great school and the kids are really, really great and so are the parents.

I help anyone who wants to cross. I just like getting out and meeting people. I dont even mind the weather I am always happy.

In his spare time Mr Constable enjoys watching action films, Formula One racing and spending time with his Hahns macaw, a green parrot who loves to learn new words. Mr Constable said:

He knows about 14 or 15 words. I have had him for about a year.

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Breaking the Shackles of Apartheid in Medicine: Frank Lipman at TEDxLowerEastSide – Video

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Breaking the Shackles of Apartheid in Medicine: Frank Lipman at TEDxLowerEastSide
Dr. Frank Lipman is the acclaimed Integrative Physician who has worked with Donna Karan, Kevin Bacon and Gwyneth Paltrow, to name just a few. From a very you...

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Tweaking MRI to Track Creatine May Spot Heart Problems Earlier, Penn Medicine Study Suggests

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Newswise PHILADELPHIA A new MRI method to map creatine at higher resolutions in the heart may help clinicians and scientists find abnormalities and disorders earlier than traditional diagnostic methods, researchers at the Perelman School of Medicine at the University of Pennsylvania suggest in a new study published online today in Nature Medicine. The preclinical findings show an advantage over less sensitive tests and point to a safer and more cost-effective approach than those with radioactive or contrasting agents.

Creatine is a naturally occurring metabolite that helps supply energy to all cells through creatine kinase reaction, including those involved in contraction of the heart. When heart tissue becomes damaged from a loss of blood supply, even in the very early stages, creatine levels drop. Researchers exploited this process in a large animal model with a method known as CEST, or chemical exchange saturation transfer, which measures specific molecules in the body, to track the creatine on a regional basis.

The team, led by Ravinder Reddy, PhD, professor of Radiology and director of the Center for Magnetic Resonance and Optical Imaging at Penn Medicine, found that imaging creatine through CEST MRI provides higher resolution compared to standard magnetic resonance spectroscopy (MRS), a commonly used technique for measuring creatine. However, its poor resolution makes it difficult to determine exactly which areas of the heart have been compromised.

Measuring creatine with CEST is a promising technique that has the potential to improve clinical decision making while treating patients with heart disorders and even other diseases, as well as spotting problems sooner, said Reddy. Beyond the sensitivity benefits and its advantage over MRS, CEST doesnt require radioactive or contrast agents used in MRI, which can have adverse effects on patients, particularly those with kidney disease, and add to costs.

Today, magnetic resonance imaging (MRI)-based stress tests are also used to identify dead heart tissuewhich is the warning sign of future problems (coronary artery disease, for instance)but its reach is limited. MRI is often coupled with contrast agents to help light up problem areas, but it is often not sensitive enough to find ischemic (but not yet infarcted) regions with deranged metabolism, said Reddy.

After a heart attack, different regions of the heart are damaged at different rates. This new technique will allow us to very precisely study regional changes that occur in the heart after heart attacks, enabling us to identify and treat patients at risk for developing heart failure before symptoms develop, said study co-author Robert C. Gorman, MD, professor of Surgery, and director of Cardiac Surgical Research at Penn Medicine.

To demonstrate CESTs ability to detect heart disease, the researchers applied the creatine CEST method in an MRI scanner, in healthy and infarcted myocardium (muscle tissue in heart) in large animals. In the process, the nuclear magnetization of amine (NH2) creatine protons is saturated by a radiofrequency pulse from the MRI. After the exchange with water, the degree of saturation is observed as the water signal drops, and thus the concentration of creatine becomes apparent. (In the body, creatine is converted to creatinine, which can be measured through blood and urine tests and is an important tool for assessing renal function.)

The team showed that the creatine CEST method can map changes in creatine levels, and pinpoint infarcted areas in heart muscle tissue, just as MRS methods can. However, they found, CEST has two orders of magnitude higher sensitivity than MRS. That advantage could help spot smaller damaged areas in the heart missed by traditional methods, the authors say.

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Tweaking MRI to Track Creatine May Spot Heart Problems Earlier, Penn Medicine Study Suggests

KC osteopathic medical school starts expansion

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The Kansas City University of Medicine and Biosciences is in the first phase of a $60 million, five-year expansion plan.

It's a step forward for a university that is recovering from controversy that began in 2009, when then-president Karen Pletz was fired and several administrators resigned. Pletz was later charged with embezzling more than $1.5 million, engaging in money laundering and falsifying tax returns. The university sued Pletz and she countersued before she committed suicide in November 2011.

All litigation involving the school and Pletz has been settled, The Kansas City Star reported ( http://bit.ly/1aHOFHC).

The new construction "demonstrates that we are committed to move forward," said Marc B. Hahn, the osteopathic medical school's president and CEO. "The only thing that we can control is what we do now. We have a great story to tell."

Work began two months ago to convert Weaver Auditorium into an academic center, and the administration building is being renovated. Other upgrades, which have not been fully detailed, are planned for the Strickland Education Pavilion and classrooms in Smith Hall. And in the future, the clinical training center at Kesselheim Hall is expected to be replaced by a 33,000-square-foot medical simulation building and clinical training facility.

Hahn, who began his job last July, said he also plans to improve the university's relationship with the city, particularly in the northeast area where the university has been located since 1916.

The university recently agreed to allow seven of its professors to treat patients at the Samuel U. Rodgers Health Center, a clinic for low-income residents, said university spokeswoman Lisa Cambridge. Faculty and medical students also work with neighborhood residents to tend a community garden that produces 2,000 pounds of fruit and vegetables a year.

With nearly 1,000 medical students, the university is the 14th largest medical school by class size in the country. It is the largest in Missouri or Kansas and is the second leading producer of primary care physicians in the two states.

The university also hopes to increase its enrollment by 50 percent or more through its two bioscience master's programs, additional bioscience programs and the possible opening of satellite campuses.

"As we do well, so does the neighborhood," Cambridge said.

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KC osteopathic medical school starts expansion

Sweet land of… conformity?

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Americans like to see themselves as rugged individualists, a nation defined by the idea that people should set their own course through life. Think of Clint Eastwood rendering justice, rule-bound superiors be damned. Think of Frank Sinatra singing My Way.

The idea that personal liberty defines America is deeply rooted, and shared across the political spectrum. The lifestyle radicals of the 60s saw themselves as heirs to this American tradition of self-expression; today, it energizes the Tea Party movement, marching to defend individual liberty from the smothering grasp of European-style collectivism.

But are Americans really so uniquely individualistic? Are we, for example, more committed individualists than people in those socialist-looking nations of Europe? The answer appears to be no.

For many years now, researchers worldwide have been conducting surveys to compare the values of people in different countries. And when it comes to questions about how much the respondents value the individual against the collective that is, how much they give priority to individual interest over the demand of groups, or personal conscience over the orders of authority Americans consistently answer in a way that favors the group over the individual. In fact, we are more likely to favor the group than Europeans are.

Surprising as it may sound, Americans are much more likely than Europeans to say that employees should follow a bosss orders even if the boss is wrong; to say that children must love their parents; and to believe that parents have a duty to sacrifice themselves for their children. We are more likely to defer to church leaders and to insist on abiding by the law. Though Americans do score high on a couple of aspects of individualism, especially where it concerns government intervening in the market, in general we are likelier than Europeans to believe that individuals should go along and get along.

American individualism is far more complex than our national myths, or the soap-box rhetoric of right and left, would have it. It is not individualism in the libertarian sense, the idea that the individual comes before any group and that personal freedom comes before any allegiance to authority. Research suggests that Americans do adhere to a particular strain of liberty one that emerged in the New World in which freedom to choose your allegiance is tempered by the expectation that you wont stray from the values of the group you choose. In a political climate where liberty is frequently wielded as a rhetorical weapon but rarely discussed in a more serious way, grasping the limits of our notion of liberty might guide us to building Americas future on a different philosophical foundation.

The image of America as the bastion of libertarianism is a long-established one. Our Founding Fathers stipulated a set of personal rights and freedoms in our key documents that was, by the standards of that day, radical. The quintessentially American philosopher Ralph Waldo Emerson, in Self-Reliance, extolled the person who does not defer to outside authority or compromise his principles for the sake of any collectivity family, church, party, community, or nation.

This quality in the American character struck observers from overseas, including Alexis de Tocqueville, who in his 1830s book, Democracy in America, famously tied the relatively new word individualism to what seemed so refreshingly new about the Americans. Popular culture today reinforces this image by making heroes of men (its almost always men) who put principle above everything else, even if perhaps especially if that makes them loners.

But in modern America, when you look at real issues where individual rights conflict with group interests, Americans dont appear to see things this way at all. Over the last few decades, scholars around the world have collaborated to mount surveys of representative samples of people from different countries. The International Social Survey Programme, or ISSP, and the World Value Surveys, or WVS, are probably the longest-running, most reliable such projects. Starting with just a handful of countries, both now pose the same questions to respondents from dozens of nations.

Their findings suggest that in several major areas, Americans are clearly less individualistic than western Europeans. One topic pits individual conscience against the demands of the state. In 2006, the ISSP asked the question In general, would you say that people should obey the law without exception, or are there exceptional occasions on which people should follow their consciences even if it means breaking the law? At 45 percent, Americans were the least likely out of nine nationalities to say that people should at least on occasion follow their consciences far fewer than, for example, the Swedes (70 percent) and the French (78 percent). Similarly, in 2003, Americans turned out to be the most likely to embrace the statement People should support their country even if the country is in the wrong.

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Sweet land of... conformity?

D.C. Notebook: Lee gives Paul a drone for his birthday

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D.C. Notebook: Lee gives Paul a drone for his birthday

What do you get the libertarian senator who has just about everything? That was the conundrum facing Sen. Mike Lee with his tea party buddy Sen. Rand Pauls birthday fast approaching. Lee decided to go with a gag gift, buying a tiny, addictively fun, drone.

Lee and Paul have been tight since they both were elected to the Senate in 2010 and given Pauls concern with drones used to target terrorists the senator held the floor for 13 hours last year lambasting the use of unmanned aerial vehicles to kill people domestically without due justice Lee thought his birthday surprise would elicit a laugh. It did.

"My good friend, Senator Mike Lee from Utah, gave me a drone," Paul said Wednesday night on Fox Newss On the Record with Greta Van Susteren.

The Kentucky Republican said he hadnt yet figured out what to do with his new toy thats the size of his hand but he had one idea.

"You may wonder, what am I going to do with a drone? Well, its got a laser. And Ive been trying to get invited to the Democrat lunch for about a year now and they wont invite me. So you know what? I think Im going to send my drone in."

Of course, Senate rules probably wouldnt permit a senator using a drone to spy on the other side of the aisle, but Paul said he was planning to "check" to see if its possible.

Go Weber Utahs federal delegation was all over the celebration of Weber State Universitys 125 anniversary. Lee turned his weekly Jell-O with the Senator event into a tribute, featuring purple gelatin with white whipped cream in homage to the schools colors. Lee posed for an Instagram shot holding a cup of Utahs favorite dessert.

And Lee made sure to celebrate the schools history in a speech to the Senate, even though hes a Brigham Young University graduate.

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D.C. Notebook: Lee gives Paul a drone for his birthday