Former Bloomington Kmart Property May See Progress As Early As Next Year – Indiana Public Media

Posted on September 19, 2019 by Dook Domini

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Former Bloomington Kmart Property May See Progress As Early As Next Year - Indiana Public Media

Why Week 3 is so crucial for Mitch Trubisky’s progress – The Athletic

Posted on September 19, 2019 by Dook Domini

This is not what the Bears envisioned.

Mitch Trubisky certainly didnt expect a Week 3 game in Washington to carry any more weight than a Monday Night Football game in September would or should.

Alas, here we are. Trubisky needs to have a good game. No more game manager. He has to show he can take care of one of the leagues worst passing defenses.

We shouldnt still be talking about a litmus test for a third-year quarterback (second in this system) entering his 30th start. But an offense that ranks 30th in yards per pass play (4.56), and a quarterback that looked overwhelmed in Week 1 and shackled by his head coach John Fox-style in Week 2, has brought us to this point.

A Week 3, out-of-division game for a 1-1 Bears team becomes a hallmark moment for Trubisky. No one in the franchise will publicly bill it that way. Trubisky is even-keeled, though his tumultuous start has tested that. Matt Nagy has championed staying steady. But the...

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Why Week 3 is so crucial for Mitch Trubisky's progress - The Athletic

Chronic Fatigue Syndrome: Progress Toward Diagnosis and Treatment, Finally? – American Council on Science and Health

Posted on September 19, 2019 by Dook Domini

Some medical conditions are especially frustrating to physicians because they lack not only effective treatments but even a reliable means of diagnosis. One of the most common of these is variously known as myalgic encephalomyelitis orchronic fatigue syndrome (ME/CFS).As the name suggests, it is asyndrome, a group of symptoms that seem to characterize, or define, an illness, even if we dont know how theyre related or what causes them. Thats different from better-understood illnesses such as solid tumors, rheumatoid arthritis, or stroke, for example.

The signs and symptoms may include fatigue, loss of memory or concentration, sore throat, swelling of neck or armpit lymph nodes, unexplained muscle or joint pain, headaches, unrefreshing sleep, and extreme exhaustion lasting more than 24 hours after physical exercise or mental stimulation (post-exertional malaise). People with ME/CFS are often incapable of performing ordinary activities, and sometimes become completely debilitated, unable even to get out of bed. The symptoms can persist for years.

The cause(s) of ME/CFS is not known. Some people may be born with a genetic predisposition for the disorder, which is then triggered by a combination of factors. Those precipitants may include viral infections; immune system dysfunction; or imbalances in hormones produced in the hypothalamus, pituitary glands or adrenal glands. Complicating the clinical picture is that ME/CFS may not be a single entity, but a spectrum of different diseases that we are currently unable to differentiate.

ME/CFS is surprisingly common. According to an Institute of Medicine (IOM)reportpublished in 2015, an estimated 836,000 to 2.5 million Americans suffer from ME/CFS, most of whom have not been diagnosed. That could change if the very preliminary report from Stanford University researchers of a diagnostic test is confirmed.

As described in the Stanfordpress release, the test employs a nanoelectronic assay, which measures changes in minuscule amounts of energy as a proxy for the health of immune cells and blood plasma.

"The diagnostic technology contains thousands of electrodes that create an electrical current, as well as chambers to hold simplified blood samples composed of immune cells and plasma. Inside the chambers, the immune cells and plasma interfere with the current, changing its flow from one end to another. The change in electrical activity is directly correlated with the health of the sample.

The idea is to stress the samples from both healthy and ill patients using salt, and then compare how each sample affects the flow of the electrical current. Changes in the current indicate changes in the cell: the bigger the change in current, the bigger the change on a cellular level. A big change isa sign that the cells and plasma are flailing under stress and incapable of processing it properly. All of the blood samples from ME/CFS patients created a clear spike in the test, whereas those from healthy controls returned data that was on a relatively even keel. The test has been applied to blood samples from 40 people, half of whom have ME/CFS and half of whom who dont. The investigators report that the test clearly identified [all of] those with ME/CFS but was negative in healthy controls."

These results are very preliminary, and it is important to note that the test measures only a proxy, or surrogate, for what is actually happening in immune cells and blood plasma. The next step should be to investigate the specificity of the test by applying it to patients with a spectrum of diseases, including some whose symptoms overlap with ME/CFS, including fibromyalgia, mononucleosis, and myofascial pain syndrome.

The researchers are also attempting to use the assay to screen for drug-based treatments, by running it before and after adding measured doses of various candidate therapeutic drugs to the patients blood samples. The theory is that if the blood samples taken from ME/CFS patients still respond poorly to stress and generate a spike in electrical current, then the drug likely didnt work. However, if a drug seems to suppress the spike in electrical activity, that could mean it is having a positive effect on the ability of the immune cells and plasma to process stress.

A different approach, by a biopharmaceutical start-up, is based on the thesis that ME/CFS could arise from the up-regulation of a specific receptor (CRF2) in the parts of the brain that govern the sensitivity of the stress response. That would, the theory goes, cause an exaggerated response to a minor stimulus, ultimately leading to the various signs and symptoms, described above, that are commonly observed in ME/CFS.Although there is no good animal model of ME/CFS, overstimulating CRF2 in healthy rats induces signs and symptoms consistent with the disease in humans; while down-regulating it, with an experimental, synthetic peptide called CT38, eliminates the ability to elicit these signs and symptoms.

A small, early-stageclinical trialin which the primary endpoint was an assessment of functional parameters following cardio-pulmonary exercise tests, conducted pre- and post-treatment, has been performed with CT38, but the results have not yet been reported.

Additional parts of the ME/CFS puzzle were provided by researchers at an Aprilconferencesponsored by the National Institutes of Health: new evidence of cardiopulmonary and nervous system abnormalities in patients with ME/CFS, which could be the etiology of their exercise intolerance.

Its early days, but we seem to be closing in on understanding, diagnosing, and maybe even treating one of our species truly awful afflictions.The glacial pace of progress serves as a reminder that we need to pursue a variety of research approaches and to get expeditious regulatory reviews of treatments once they reach clinical trials.

Henry I. Miller, a physician, is a Senior Fellow at the Pacific Research Institute. He was a Research Fellow at the National Institutes of Health and the founding director of the Office of Biotechnology at the FDA. Please follow him on Twitter: @henryimiller.

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Chronic Fatigue Syndrome: Progress Toward Diagnosis and Treatment, Finally? - American Council on Science and Health

Michigan’s offense remains a work in progress, and Wisconsin looms – MLive.com

Posted on September 19, 2019 by Dook Domini

ANN ARBOR Jim Harbaugh spoke of the need to take better care of the football and fix some of the offenses sloppy play.

That was after Week 1.

Then came Michigans second game of the season, against Army, and many of the same problems creeped back up. More fumbles. More penalties. Missed opportunities.

The next thing the 11th-ranked Wolverines knew, they were headed to overtime against unranked Army, at home, facing the possibility of starting the season with a 1-1 record.

We know how it finished, Michigan escaping with a 24-21 victory thanks to a 43-yard field goal and defensive turnover on the final drive of the game. And then came a pivotal bye week.

I wouldnt say we lost any confidence at all, starting left guard and offensive captain Ben Bredeson said Monday. I think the great thing that these weeks showed is the things that we need to work on. So far, through the bye and and now rolling over, we can really carry on some of the smaller details that we need to correct.

- MORE: Michigan spent bye week tackling fumbles, penalties

That correction is required given the opponent that looms. Michigan opens Big Ten play against No. 13 Wisconsin on Saturday (noon, FOX), with the 2-0 Badgers having outscored their first two opponents 110-0.

They, too, are coming off a bye, and still possess the No. 1 defense in the country after three weeks. Wisconsin is only allowing 107.5 yards per game, aided by the 58 gained by Central Michigan in a 61-0 smashing on Sept. 7.

Michigan is not CMU of course, nor is it South Florida, which mustered just 26 yards on the ground at home against the Badgers in Week 1. But a tough, rugged Wisconsin team awaits.

The challenge of this game is big, Jim Harbaugh told reporters Monday. "Weve played Wisconsin now three times, (and) going on the fourth. Theyre just good every year. They seem to be every time we face them. A really talented, veteran, well-coached football team.

And playing at Camp-Randall (Stadium), thats a tough venue. Thats a tough win to get. We havent won in four or five tries, so its a big game for us. A big challenge.

Michigan has not won a football game in Madison since 2001, a stretch of four straight games (the two teams did not play there from 2010 to 2016) that includes a 24-10 loss in 2017, a season that first went off the rails with an ugly Big Ten loss at Penn State.

In both of those games, the Wolverines defense was unable to get the big stop, while their offense failed to keep up. If they are not careful on Saturday, it could be a repeat performance.

Now, not all is lost. Michigan (2-0) can clean up the turnovers (6) and penalties (10) like it did early in the season in 2018, and its likely to happen. Harbaugh-led Michigan teams rarely go long stretches making the same mistakes over. Especially with such a veteran-laden group on the offensive side of the ball.

And when you peel back the fumbles and penalties through the first two games, theres plenty of good. Plays developing as they should. Throws being made like they should. Receivers getting open.

If you watch the tape like we did, the explosive plays were all there, Bredeson said. There was always just one thing wrong. Like one thing that was wrong. Like one thing that was holding everything back.

That sentiment is shared amongst players and coaches. First-year offensive coordinator Josh Gattis emphasized the missed opportunities last week during the bye, making it a point of saying the mental mistakes would get corrected.

- MORE: Harbaugh coy on Michigans injured players ahead of Wisconsin

Its plausible to presume that they will. But will it come in time? Just this week, Bredeson admitted that Michigans new shotgun-style, RPO-injected spread offense is a complicated one. Theres a lot of moving parts and plenty to pay attention to.

Which is why, when asked this week about Shea Patterson (credited with four fumbles in the first two games this season) and the improvement hed like to see out of his senior quarterback, Harbaugh flipped it to the offense.

Just everybody on that side of the ball, that unit, more efficient, Harbaugh said. "Just cohesion. Everybody playing efficiently and with good ball security. Taking advantage of big plays when theyre there.

But also the efficient factor of run and pass, what we do as an offense. Consistently move the ball.

Harbaugh likes the number of first downs Michigan has obtained (49) through the first two games, and at times his team has been able to move the ball without trouble. But explosive plays have been few and far between.

Which brings us to this Saturday, the first road game of the season for an eager Michigan team looking to show everyone what it really can do offensively. Because there have been glimpses, like the first half of the opener against Middle Tennessee State: Shots down the field. Multiple receivers targeted. Holes opening along the offensive line.

- MORE: Michigan opens as slight underdog at Wisconsin

Were tired of (talking) ourselves, saying the things were going to change, tight end Nick Eubanks said. Actually doing it so people get a chance to see that, thats the one thing were working on.

But Wisconsin is not Middle Tennessee State, nor Army. The Badgers are big up front and faster than both teams in the secondary. Plus Michigan is tasked with having to deal with the crowd noise of 80,000-plus spectators, majority Wisconsin fans. For a team still learning how to run a shotgun-only offense, it wont be an easy task.

Factor all of that in including the mistake-filled first two games and its probably why the oddsmakers in Las Vegas list Michigan as an underdog on Saturday for the first time in over a year.

While the Big Ten race certainly wont be decided on Saturday, the game will go a long way in determining where this Michigan offense stands. Another off-kilter performance, and loss, puts the pressure on Gattis and Harbaugh. A well-oiled machine, as Harbaugh likes to describe it, could put the rest of the conference on notice.

This weekend, we get the first real glimpse into what kind of team Michigan really is. Not only do the Wolverines have to figure themselves out on offense, but the defense will have its hands full with all-Big Ten running back Jonathan Taylor, who has 237 yards and five touchdowns rushing on 35 carries.

The importance of being good, Harbaugh said. Thats what Ive always thought of with road games. The best way to win them is be a good team.

More Michigan football coverage:

Jim Harbaugh and Michigan football: Cash is flowing but the trophy case is empty

U-M football found its backup RB during the bye week

Kickoff time, TV announced for Michigan footballs game vs. Rutgers

Michigan drops again in AP Top 25 poll

Zach Charbonnet has always been a beast, former teammate says

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Michigan's offense remains a work in progress, and Wisconsin looms - MLive.com

Progress or window dressing? New Ferguson-inspired report analyzes police reforms – STLtoday.com

Posted on September 19, 2019 by Dook Domini

ST. LOUIS A report released Monday seeks to answer whether police departments are making real progress toward racial equality or just checking a box.

The anti-bias training that comprises 1.4% of all training time for Webster Groves police officers is entirely online and costs $4.99?

Furtado, along with organization co-chair Rebeccah Bennett and lead catalyst David Dwight IV, presented the groups second report, titled The State of Police Reform, at the Deaconess Center for Child Well-Being.

They plan to host three town hall meetings throughout the area to discuss the report, which concluded, St. Louis is in desperate need of effective and holistic public safety that doesnt rely on the failed arrest-and-incarcerate model.

The groups report focused on three departments. Here are some of the findings:

Ferguson: A consent decree issued by the U.S. Department of Justice is a legal mandate forcing the department to change, but the restrictive procedures of that mandate also can slow things down. The group also noted that Ferguson has had seven police chiefs in the past five years.

Ferguson is an eye-opening example of ... extreme volatility in leadership and how that degree of upheaval can impede reform, according to the report.

St. Louis: The size of the department leads to particularly complex dynamics including a larger leadership structure that often precludes a strong, consistent and clear commitment to one platform, according to the report. The department is the largest in the region, with about 1,100 commissioned officers, and it is governed by a police chief, a mayor and a public safety director, who, if you look at their actions, are misaligned, Furtado said.

The department also has a nearly constant flux of legal action both spurring and slowing change, as well as an oftentimes oppositional police union, according to the report.

North County Police Cooperative: The group called the department, which is based in Vinita Park, organically grown with community-oriented roots. The department formed in 2015 as several municipalities consolidated their police departments in north St. Louis County.

There have been advances in programs that help foster racial equality, but not as much progress on the departments policies, according to the report.

Looking at the region as a whole, the group called for devoting more resources toward addressing the root causes of crime.

Rebeccah Bennett, co-chair of Forward Through Ferguson, speaks during the organization's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

Audience members listen during Forward Through Ferguson's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

Amber Norris, from St. Louis, looks at poster boards explaining information released in a new report following Forward Through Ferguson's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

Becky Patel, 41, from Clayton, asks a question during Forward Through Ferguson's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

Karishma Furtado, research and data catalyst at Forward Through Ferguson, speaks during the organization's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

Chelesa Holden, 30, asks a question during Forward Through Ferguson's press conference held at the Deaconess Center for Child Well-Being, 1000 North Vandeventer Ave., on Monday, Sept. 16, 2019. Members of Forward Through Ferguson spoke about a newly released report that focuses on the state of St. Louis area police reform efforts. Photo by Christine Tannous, ctannous@post-dispatch.com

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Progress or window dressing? New Ferguson-inspired report analyzes police reforms - STLtoday.com

Poulsbo Police drone captures burglary in progress – Kitsap Daily News

Posted on September 19, 2019 by Dook Domini

One suspect was arrested after being caught in the act of a burglary at Advanced Sales and Rentals on Viking Avenue by a Poulsbo Police Department UAS (Unmanned Aerial System) device scoping out the area.

According to a press release from Poulsbo PD, over the course of the last week, the shop had been burglarized twice. In each case, the suspects had cut through the chain-link fence and entered the rental yard taking unspecified items.

As a result, Poulsbo officers have been conducting frequent checks of the business.

Just before midnight on Sept. 12 Poulsbo Police Sergent Howard Leeming was checking on the business, but rather than doing it on foot, he piloted the UAS device to check the site from above, to which his timing could not have been better.

Sgt. Leeming was able to locate two suspects in the process of burglarizing the business a third time.

Additional officers responded to the scene to set up a containment area including a K-9 Unit from the Kitsap County Sheriffs Office.

Officers ordered the suspects to exit the location and surrender. After several orders to comply with the officers, the K-9 unit made up of Deputy Aaron Baker and K-9 Heiko were deployed. The team captured one suspect while the other got away on foot.

The captured suspect was identified ad 38-year-old Christopher Baker of Poulsbo.

Its a great example of how this technology, paired with teamwork and initiative, is so beneficial to law enforcement, Poulsbo Police Chief Dan Schoonmaker said.

The investigation into this case is still ongoing and anyone with further information regarding the burglaries is encouraged to contact Poulsbo PD.

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Poulsbo Police drone captures burglary in progress - Kitsap Daily News

Progress – High Productivity Application Development for …

Posted on June 3, 2019 by Dook Domini

Deliver the Apps Your Business NeedsFaster

Unlike traditional low-code platforms, Progress lets you build consumer-scale, multichannel apps on a modern serverless cloud platform. Enterprise integration is a few clicks away, and the JavaScript-based platform reuses the skills your developers already have.

Build mobile, web and chat experiences at consumer-grade scale with open source frontend frameworks integrated with a secure serverless cloud platform.

Automatically integrate new enterprise apps with existing systems, data and identity services via out-of-the-box configurations. Modern serverless platform powers rapid development.

JavaScript-based platform means no re-training, no platform lock-in. Microservices enable lower cost development with unmatched agility.

Success Stories

After doing our research, Progress Health Cloud was the most reliable and mature platform. We also liked that Progress had a short-term and long-term vision for the healthcare space.

Not being iOS, Android or backend experts, without Progress Kinvey, we can safely say we would not have been able to react to feedback and pivot our idea so quickly.

Kinvey makes product innovation simple with no IT overhead. Decoupling the user interface from the backend allows our developers to focus on product innovation instead of building or maintaining the backend platform.

New & Trending

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Progress - High Productivity Application Development for ...

Progress Residential | Rental homes with amenities in …

Posted on June 3, 2019 by Dook Domini

Find A Perfect Rental Home Its time to start enjoying the perks of living in a single-family rental home! Progress Residentials homes are located in the countrys most desirable communities and include spacious backyards, garages and room to grow. Were also pet-friendly! We dont place restrictions on size, breed or the number of pets you have. Let us help you find your dream home today.

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Progress Residential | Rental homes with amenities in great …

Posted on November 11, 2018 by Dook Domini

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progress – Wiktionary

Posted on November 11, 2018 by Dook Domini

English[edit]Etymology 1[edit]

From Old French progres (a going forward), from Latin prgressus (an advance), from the participle stem of prgred (to go forward, advance, develop), from pro- (forth, before) + gradi (to walk, go).

progress (countable and uncountable, plural progresses)

a moving forward

advance or growth of civilization

From the noun. Lapsed into disuse in the 17th century, except in the US. Considered an Americanism on reintroduction to use in the UK.

progress (third-person singular simple present progresses, present participle progressing, simple past and past participle progressed)

to become better or more complete

Translations to be checked

terms related to progress

Via other European languages, ultimately borrowed from Latin prgressus (an advance), from the participle stem of prgred (to go forward, advance, develop), from pro- (forth, before) + gradi (to walk, go).

progressm (1st declension)

socilais progress social progress

cilvces progress humanity's progress

raoanas efektivittes paaugstinans pamats ir zintniski tehniskais progress the basis for the increase in production effectivity is scientific and technical progress

mkslas progress - t nav vienkra attstba art progress: this is no simple evolution

Declension of progress (1st declension)

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progress - Wiktionary

Progress (spacecraft) – Wikipedia

Posted on November 11, 2018 by Dook Domini

The Progress (Russian: ) is a Russian expendable cargo spacecraft. Its purpose is to deliver supplies needed to sustain human presence in orbit. While it does not carry a crew it can be boarded by astronauts when docked with a space station, hence it being classified as manned by its manufacturer.[1][2][3] Progress is derived from the manned Soyuz spacecraft and launches on the same vehicle, a Soyuz rocket.

Progress has supported space stations as early as Salyut 6 and as recently as the International Space Station. Each year there are between three and four Progress flights to the ISS. A Progress remains docked until shortly before being replaced with a new one or a Soyuz (which will use the same docking port). Then it is filled with waste, disconnected, and de-orbited, at which point it burns up in the atmosphere. Due to the variation in Progress vehicles flown to the ISS, NASA uses its own nomenclature where "ISS 1P" means the first Progress spacecraft to ISS.

Progress was developed because of the need for a constant source of supplies to make long duration space missions possible. It was determined that cosmonauts needed an inflow of consumables (food, water, air, etc.), plus there was a need for maintenance items and scientific payloads that necessitated a dedicated cargo carrier. Such payloads were impractical to launch with passengers in the restricted space of a Soyuz. As of December 1, 2016 there have been 155 Progress flights with three failures. All three failures have occurred since 2011.

Progress is of much the same size and shape as Soyuz. It consists of three modules:

Reduction in mass was possible because the Progress was designed to be unmanned and disposable. This means that there is no need for bulky life support systems and heat shields. A small amount of weight is saved due to the lack of automatic rescue crews system and lack of parachutes. The spacecraft also has no ability to split into separate modules. After undocking, the spacecraft performs a retrofire and burns up in the atmosphere.

There were many small variations between the different flights, but the major upgrades are reflected in the change of name.

There were 42 spacecraft built using the initial Progress design, the last one being launched in May 1990.

The bureau in charge of designing the freighter was TsKBEM (now RKK Energia). They began work on the design in mid-1973, assigning Progress the GRAU index 11F615A15. The design was complete by February 1974, and the first production model was ready for launch in November 1977. Progress 1 launched on 20 January 1978 aboard the same rocket used to launch the Soyuz. It still featured the same launch shroud as the Soyuz, though this was purely for aerodynamic purposes as the launch escape system had been deactivated.

This first version of Progress had a mass of 7,020kg and carried 2,300kg of cargo, or 30% of its launch mass. It had the same diameter as the Soyuz at 2.2 metres, but was 8 metres in lengthslightly longer. The autonomous flight time was 3 days, the same time as that of the Soyuz ferry. It could spend one month docked. Progress always docked to the aft port of the station it was resupplying (the aft being where the main rocket engines of the station and their tankage, for refueling by the Progress, are located).

The upgraded Progress M (GRAU: 11F615A55, manufacturer's designation: 7K-TGM) was first launched in August 1989. The first 43 flights all went to Mir; following Mir's re-entry, Progress was used as the resupply vehicle for the International Space Station. As of August 2014, there have been 56 flights to the ISS and more are scheduled.[4]

The Progress M is essentially the same spacecraft as the Progress, but it features improvements based on the Soyuz T and TM designs. It can spend up to 30 days in autonomous flight and is able to carry 100kg more. Also, unlike the old Progress crafts, it can return items to Earth. This is accomplished by using the Raduga capsule, which can carry up to 150kg of cargo. It is 1.5 m long and 60cm in diameter and has a "dry mass" of 350kg. Progress M can also dock to the forward port of the station and still transfer fuel. It uses the same rendezvous system as the Soyuz, and it features solar panels for the first time.

A new modification of the Progress spacecraft, with new TsVM-101 digital flight computer and MBITS digital telemetry system,[5] was first launched on 26 November 2008, at 12:38 UTC from the Kazakhstan's Baikonur Cosmodrome spaceport aboard a Russian Soyuz rocket. The first spacecraft of this series was Progress M-01M.

The spacecraft belongs to the so-called 400 series (GRAU: 11F615A60), and all modifications applied to it were subsequently used in the production of new Soyuz-TMA-M[6] manned spacecraft.

Progress M-27M was launched on April 28, 2015, but communication with the vessel was lost soon after, and it was destroyed as it re-entered the atmosphere on 8 May 2015.[7] The last launch was Progress M-29M

Progress M1 is another variant, capable of carrying more propellant (but less total cargo) to the space stations. There have been 11 of these flights.

Progress M2 was a planned variant, which was a proposed design for the proposed Mir-2 space station, but was dropped due to financial issues. The M2 variant would have a larger service module for larger cargo or space station modules and would have been launched on a Zenit rocket as the spacecraft is bigger.

Progress MS is an improved variant which first launched on 21 December 2015.[8] It has the following improvements:[9]

This article needs to be updated. Please update this article to reflect recent events or newly available information. (June 2018)

Progress spacecraft are currently used to resupply the International Space Station (ISS). Between 1 February 2003 and 26 July 2005, they were the only spacecraft available to transport large quantities of supplies to the station, as the Space Shuttle fleet was grounded after the breakup of Columbia at the end of STS-107. For ISS missions, the Progress M1 variant is used, which moves the water tanks from the propellant and refueling module to the pressurized section, and as a result is able to carry more propellant.[citation needed] Progress M-67, the final flight of a Progress-M spacecraft, was launched 24 July 2009 on a Soyuz-U.

More recently, on the 9th of July 2018, Progress MS-09 broke a previous record by reaching the International Space Station in 3 hours and 48 minutes with a 3 ton payload of propellant, oxygen, food, and other supplies. After the spacecraft docks, the six crewmembers of Expedition 56 will spend the next few months unloading the cargo, which includes 1,170 lbs. (530 kilograms) of propellant, 115 lbs. (52 kg) of oxygen gas, 930 lbs. (420 kg) of water, and 3,450 lbs. (1,565 kg) of other "dry" cargo like food and other equipment, NASA public affairs officer Dan Huot told the media.

The European Space Agency (ESA) operated its own type of robotic supply freighter, the Automated Transfer Vehicle (ATV). The first of these, named Jules Verne, was launched at 04:03 GMT on 9 March 2008. ATVs can carry up to 8.85 tonnes of cargo into space, roughly three times as much as the Progress, and were launched annually by Ariane 5 rockets from 2011-2014 as part of ESA contribution to ISS upkeep. The design is currently being adopted as the Service Module of the NASA Orion spacecraft.

NASA's Orion spacecraft, which will replace the Space Shuttle, was initially designed to have an unmanned variant of the Crew Module similar to Progress, however this capability has since[when?] been removed.[10] SpaceX's commercial (private owned) Dragon spacecraft and Orbital Sciences' Cygnus spacecraft also handle American logistics to the International Space Station.

RKK Energia has proposed the Parom (ferry) spacecraft as a replacement for Progress. This new spacecraft would retrieve either the proposed Kliper spacecraft or any cargo container with a Russian airlock and weighing up to 15 short tons (14t) back to the ISS.[citation needed]

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Progress (spacecraft) - Wikipedia

Gene Therapy Could Become as Easy to Get as a Flu Shot

Posted on October 29, 2018 by Dook Domini

Tech Poor

Genetic engineering research is time-consuming and cost-prohibitive. If we want gene editing to help us all live longer, healthier lives, we need to streamline the process.

That’s Synthego’s stance, anyway.

The startup asserts that genetic engineering research is both time-consuming and cost-prohibitive, and it believes those characteristics are slowing down progress in the field. To address the issue, it sells engineered cells and CRISPR kits to researchers. This reportedly saves those researchers both time and money, and now, Synthego has an additional $110 million with which to further develop its technologies.

Stacks on Stacks

On Tuesday, Synthego announced it closed a $110 million investment round. Leading the investment was Founders Fund, a venture capital firm that was an early backer of SpaceX and Facebook. As you’d expect, the language of the announcement is a cross between medical terminology and the lingo of a Silicon Valley startup.

“This new funding allows us to expand our reach and build out our full stack platform capabilities at a perfect time,” said Synthego CEO Paul Dabrowski in a press release. “Biological medicines are on the cusp of a revolution with the coming curative cell and gene therapies, and we are proud to support this industry.”

CRISPR for All

Helping scientists conduct gene editing research is just one part of the equation, though — Synthego is also very concerned about how the gene therapies developed today will affect the lives of people tomorrow.

“The headlines around genome editing make it sound simple, but the reality is that bringing laboratory discoveries to humans is a complex process requiring specialized expertise, reagents, and commitment,” Synthego advisory board member Matthew Porteus said in the release.

Synthego is hopeful that the technologies it develops now will help democratize access to those therapies. According to Dabrowski, “Our vision is a future where cell and gene therapies are ultimately as accessible as vaccines, so that everyone can benefit from next-generation cures.”

More on gene therapy: The First “Cell-Free” CRISPR Tech Is Here to Personalize Cancer Treatment

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Gene Therapy Could Become as Easy to Get as a Flu Shot

Meet the Researchers Bringing Bizarre AI Creations to Life

Posted on October 29, 2018 by Dook Domini

It’s date night! Time to throw on your oversized graduation cap and ruffly shirt, spritz yourself with some of your new “Hivinga” perfume, and meet your better half for some sweet potato, beans, and brie pizza covered with “snipped caramel cheese.”

Wait, what? Things that don’t seem quite right here. Oh, right, that’s because all these date night tips came from a series of artificial intelligence algorithms custom-built to generate new clothing designs, pizza recipes, and perfumes.

Whatever bizarre (and, frankly, unappetizing) ideas the AI systems conjured were built by a group of MIT researchers and students called How to Generate (Almost) Anything. The team builds and trains algorithms that can tackle seemingly creative tasks to come up with brand new designs for each week’s theme. The researchers then build, bake, or stitch together whatever the AI system came up with. Their goal: these strange, unusable things will help the average person understand and appreciate what AI can do, and what it can’t yet.

“The larger goal of the project is to democratize AI for the public. Currently, the creative usage of AI is within the reach of AI practitioners,” computer scientist Pinar Yanardag, the MIT postdoctoral researcher who founded the group, told Futurism.

Most of the projects used machine learning algorithms that, upon being trained with thousands of examples of pizzas and perfume recipes, spat out unique creations that were sort of like the thing they were supposed to create, but just a little bit off. Often, the results were outlandish and alien. For instance, several pizzas called for fictional ingredients or skipped crucial steps in the baking process.

But two of the projects, the algorithms that designed dresses and graffiti, used a generative adversarial network (GAN), a type of algorithm used to create things that seem like the real deal. As a result, the fashionbot and graffitibot were a touch less goofy than all the others.

Image Credit: How to Generate (Almost) Anything

Granted, the algorithms could produce slightly less ridiculous results — like, for instance, pizza recipes that actually result in something edible. But that wasn’t what Yanardag and her team wanted to accomplish here. Their primary goal was to make something that would be fun and accessible for the average person to use.

Every week, the team releases a new video highlighting the algorithm they trained and what it came up with. They’re working on a user-friendly tool that would let people play around with the algorithm — no technical skills required — and generate their own versions of that week’s theme, whether it’s graffiti, pizza, perfume, or music. That tool is still a work in progress, but the group shares extra designs and recipes from their algorithms for people to try making at home.

Normally, bizarre AI creations are merely the stuff of twitter threads. By making the algorithmic output tangible, Yanardag hopes that people will develop a better grasp of machine learning’s capabilities. Advanced AI, Yanardag’s project suggests, can be used to help us in our creative endeavors, not simply replace us.

More on “creative” AI: Artificial Intelligence Is Making Video Game Levels So Good That Even Other AI Thinks They’re Man-Made

(10/17/2018, 3:15 PM) Editor’s note: a previous version of this article said that the group’s tool for letting the public generate their own AI creations was live. The article has been updated to reflect that the tool is a work in progress. For now, the group is sharing extra recipes and designs that their algorithm generated but they didn’t make in real life.

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Posted on September 30, 2018 by Dook Domini