Report: NBA Making Progress on Plan for 8 Teams Not Included in Orlando Restart – Bleacher Report

Rick Bowmer/Associated Press

The NBA has reportedly "progressed" in discussions about the potential for group workouts and scrimmages involving the eight teams that didn't qualify for the resumption of the 2019-20 season at the Disney World complex in Orlando, Florida.

Rick Bonnell of the Charlotte Observer reported Friday the current proposal under discussion calls for a week of practices at a team's home facility followed by two weeks of workouts and possibly some scrimmages in hub cities, but the plan still needs final approval from the league and Players Association.

The Atlanta Hawks, Charlotte Hornets, Chicago Bulls, Cleveland Cavaliers, Detroit Pistons, Golden State Warriors, Minnesota Timberwolves and New York Knicks didn't qualify for the shortened eight-game finish to the regular season in Orlando.

In turn, those organizations are facing the potential of nearly nine months without competitive basketball with the 2020-21 campaign not scheduled to start until Dec. 1. The current season was halted March 11.

NBPA executive director Michele Roberts raised concerns about whether the league could provide an equally safe environment for those teams as the ones competing for a championship in Orlando.

"I know there are some players, particularly young players, that seem concerned they're not getting enough [opportunities]. I think our teams are incredibly smart and creative and can come up with ways to get their guys engaged, if not now, before the season starts," Robertstold reportersin June. "But I am very concerned and frankly...in terms of play that doesn't have the same guarantees of safety and health that we've provided for the teams in Orlando."

There are also questions about whether veterans would take part in the scrimmages or if it would become more of an informal Summer League setting with mostly young players.

"I probably won't play if it gets approved," an unnamed Cavs player toldChris Fedorof Cleveland.com in early July. "Doubt many vets will."

Hornets head coach James Borrego told Bonnell he believes the eight teams currently sitting on the sidelines will be at a significant competitive disadvantage heading toward next season if no plan is approved.

"We need the door flung open, so we can get after this thing," Borrego said.

A final decision could be announced as early as next week, per Bonnell.

Scrimmages have already started to take place in Orlando with the regular season set to resume Thursday.

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Report: NBA Making Progress on Plan for 8 Teams Not Included in Orlando Restart - Bleacher Report

Pence to tout incredible progress on a coronavirus vaccine next week in Florida – Tampa Bay Times

Vice President Mike Pence is headed to Miami Monday to promote the Trump administrations progress on efforts to bring a coronavirus vaccine to market.

Pences office announced Thursday that he is scheduled to visit the University of Miami next week to mark the beginning of Phase III trials for a coronavirus vaccine.

The university announced this month that it was looking for volunteers to participate in a study led by the National Institute of Allergy and Infectious Diseases COVID-19 Prevention Network in which 1,000 people will be injected with a potential vaccine by Moderna.

The trial, which is expected to begin next week, is part of a 30,000-person study.

During his visit, Pence, the head of the White Houses coronavirus task force, will participate in a roundtable with university leaders and researchers on the incredible progress of a coronavirus vaccine, Pences office announced in a press release. Pence will speak to the press before returning to Washington.

Pences visit is the latest symptom of the increased attention by the White House to the outbreak in Miami, where positive cases and hospitalizations have surged in recent weeks.

U.S. Surgeon General Jerome Adams visited Miami Thursday and held a press conference at the Camillus House homeless shelter. The previous day, task force response coordinator Deborah Birx warned on a private call that Miami was among 11 cities that should take aggressive steps to slow the spread of the virus.

Miami Herald staff writer Michelle Marchante contributed to this report.

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Pence to tout incredible progress on a coronavirus vaccine next week in Florida - Tampa Bay Times

Oregon Shows Progress in Tackling Unemployment Numbers – Governing

(TNS) The Oregon Employment Department missed its goal for the third straight week in processing thousands of unpaid benefits claims for self-employed workers who are out of a job during the pandemic.

And the beleaguered departments phone lines suffered fresh outages Tuesday and Wednesday, making it impossible for callers to reach the state to resolve problems with their claims.

Still, there are signs of progress that suggest Oregon is beginning to get a handle on the huge volume of unpaid jobless claims that left tens of thousands of unemployed workers going without income through the heart of the pandemic.

The department has now paid $3.2 billion in benefits since Oregon began its shutdown in March. This time last month there were 70,000 self-employed workers waiting for aid under the new Pandemic Unemployment Assistance program that Congress established in March. Many of those had been waiting for several months for their checks.

The department has whittled that backlog down to 44,000 unprocessed claims, moving more slowly than anticipated. The trajectory for clearing those claims is accelerating, though, and interim director David Gerstenfeld said Wednesday he is increasingly optimistic of working through those 70,000 claims by the Aug. 8 target date he set in June.

Were turning the corner, Gerstenfeld said on his weekly media call Wednesday.

The department has been aided in part by a $240,000,Google-based technology upgrade implemented last Fridayto automate some parts of the claims processing for self-employed workers.

In at least a few cases, the new system appears to have interrupted benefits payments people had been receiving. But Gerstenfeld said its been a huge net positive overall, with automation freeing up his staff to begin working unprocessed claims and accelerate payments.

State lawmakersapproved $500 relief paymentslast week for as many as 70,000 Oregonians who have been waiting the longest for their unemployment benefits. State administrators said at the time it could take several weeks to begin payments, but the Legislatures Democratic leadership indicated Wednesday they have made good progress and hope to launch the program by the end of July.

As Oregon makes advances in other areas, though, the employment department is encountering new problems.

For example, the department has whittled the number of regular, unprocessed jobless claims down from more than 100,000 last spring to just 2,600 now.

Processed claims arent always paid, though. Some need an additional review called adjudication. Gerstenfeld said the typical waiting period for adjudicated claims has grown from 10 weeks to as many as 14 weeks meaning many people with legitimate claims must wait months to see their benefits.

Every Oregon claim is still subject to a one-week period when benefits arent paid, even though Congress funded a waiver of the so-called waiting week in March. The states antiquated computers havent been able to accommodate the change.

The employment department says it will begin attempting to address the waiting week issue in August, but has cautioned it may not be able to implement the waiver by a federal deadline at the end of the year. That would leave hundreds of millions of dollars in federal benefits for Oregonians permanently unpaid, unless the state can secure additional latitude from the feds.

Additionally, this weeks phone outages exacerbated one of the departments thorniest issues.

The department relies primarily on phone calls to resolve questions about unpaid claims and the phones lines have been jammed since March due to the huge volume of new jobless claims and the states byzantine system for processing them.

Also Wednesday, Gerstenfeld disclosed that three more employment department workers have tested positive for the coronavirus. That brings the total number of infections among its staff to 16.

The outbreaks have slowed claims processing, at least modestly, andprompted the closure of the departments Gresham facility earlier this month. Gerstenfeld said that office will reopen Friday, and said the departmentnow requires its staff to wear masksin most situations.

Weve been urging these measures for some time and theyre now mandatory, Gerstenfeld said.

2020 The Oregonian (Portland, Ore.)Distributed byTribune Content Agency, LLC.

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Oregon Shows Progress in Tackling Unemployment Numbers - Governing

Dinwiddie Airport and Industrial Authority opens new executive hangars – Progress Index

Contributed Report

SundayJul26,2020at1:15PM

DINWIDDIE The Dinwiddie County Airport and Industrial Authority, located in North Dinwiddie held a ribbon-cutting ceremony earlier this month for four brand-new executive hangars.

The new executive hangars are located on the front row near the terminal building with access to the taxiway and runway. Each 60 ft. x 60 ft. hangar includes a private bathroom, large electric doors, LED lighting, and night exterior lighting, making them ideal for single and multi-aircraft fleets.

Richard Taylor, chairman of the Dinwiddie Airport and Industrial Authority stated, "These new executive hangars will have a positive impact on economic development in Dinwiddie County, and the region, with a unique offering of corporate hangar space to existing businesses and prospective businesses considering the region."

Dr. Mark Moore is a member of the Board of Supervisors as well as the Dinwiddie Airport and Industrial Authority. Regarding the project he shared, "The Dinwiddie Airport is a strong economic development asset. We believe the addition of these executive hangars will be an attractive option for corporate jets. This investment will allow us to meet the growing needs of the corporate community in Dinwiddie County and our region."

Airport Manager, Jeremy Pultz, stated "This project is just one of many great things that are happening at the Dinwiddie County Airport. We have assembled a new operational team, added new executive hangars and are adopting a new approach to doing business." Pultz added, "We are grateful for the assistance of the Virginia Department of Aviation and Dinwiddie County for helping take the Dinwiddie County Airport to the next level."

For additional information on the Dinwiddie Airport, visit http://www.ptbairport.com.

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Dinwiddie Airport and Industrial Authority opens new executive hangars - Progress Index

The Halted Progress of Criminal-Justice Reform – The New Yorker

The cause of criminal-justice reform has been, in recent years, a welcome exception to the extreme polarization that has afflicted so much of our politics. Since 2008, the prison population has dropped in most parts of the country, in both red states and blue. Its gone down sixteen per cent in Louisiana and twenty-two per cent in South Carolina, which is roughly similar to reductions in more liberal places, such as California (twenty-six per cent) and New York (twenty-one per cent). The fight against mass incarceration even engendered a brief moment of bipartisanship in Washington, in 2018, when Congress overwhelmingly passed, and President Trump signed, the First Step Act, which made modest improvements in federal sentencing practices.

But this progress, at least at the federal level, has come to a halt. In the weeks since protests erupted around the nation following the murder of George Floyd, in Minneapolis, on May 25th, the President has returned to the law and order bluster that characterized his 2016 campaign. More to the point, the Justice Department, under Attorney General William Barr, has engaged in precisely the kinds of excesses that the reform movement has endeavored to correct. Most of the protests were peaceful, of course, but there was some violence and destruction of property. These sorts of crimes have traditionally belonged in the bailiwick of state prosecutors, who handle most violent crime in the United States. Yet Barrs prosecutors have stepped in and charged at least seventy people with crimes in connection with the protests. In Mobile, Alabama, a protester allegedly used a bat to break a window of a police cruiser. Such an act is a paradigmatic state crimean assaultbut federal prosecutors contrived to bring a case for civil disorder, drawing on a rarely used federal law. Bringing the case in federal court allows Barr to posture against the protesters and, even more important, to make them eligible for longer prison sentences, as is usually the case in federal prosecutions.

The most egregious example of this kind of federal excess is taking place in New York, where prosecutors in Brooklyn may be on the verge of responding to a crime with an injustice. On May 29th, two well-regarded lawyers, Colinford Mattis and Urooj Rahman, participated in protests in Fort Greene. According to the complaint filed in federal court, just after midnight, Rahman stepped out of a minivan driven by Mattis and flung a Molotov cocktail through a broken window of an unoccupied police car. (In another part of Brooklyn, Samantha Shader, a twenty-seven-year-old woman from upstate New York, was charged in a separate Molotov-cocktail attack on a police van; neither attack caused any injuries.)

The two lawyers are both in their early thirties. Mattis is a graduate of Princeton and of New York Universitys law school, and he worked until recently at a well-known corporate law firm in Manhattan. He is active in community affairs in Brooklyn, and is responsible for the care of several young family members. Rahman, a graduate of Fordham Universitys college and law school, worked at Bronx Legal Services. Neither had a criminal record. (Shader did have a record of various arrests in different parts of the country.) Mattis and Rahman have pleaded not guilty, but the case against them appears strong. According to prosecutors, there is video evidence of Rahman throwing the improvised bomb, and police found the ingredients to make Molotov cocktails in Mattiss van.

In bringing the case against them, though, the Justice Department has engaged in grotesque overreach. If convicted of the charges in the indictment, Mattis and Rahman face a minimum of forty-five years and a maximum of life in prison. (If they were prosecuted in state court, as they should be, they would likely face five years or less.) The case demonstrates the perversity of mandatory-minimum sentences, which remain common in federal court, despite the changes wrought by the First Step Act. The problems with mandatory minimums only begin with the simple fact that they keep people in prison for too many years. They also concentrate power in the hands of prosecutors and remove discretion from judges, who usually have a broader perspective on the appropriate levels of punishment. Moreover, mandatory minimums warp the entire judicial system, by putting unbearable pressure on defendants (and their lawyers) to enter guilty pleas and avoid the risk posed by a trial. (Prosecutors often waive the minimums if defendants offer to plead guilty.)

The case of Mattis and Rahman illustrates this point clearly. Faced with the certainty of decades of prison time if convicted by a jury, what defendant wouldnt try to cut a deal for a lesser sentence? In federal court today, a remarkable ninety-seven per cent of defendants plead guilty rather than go to trial. But a system in which practically no one goes to trial gives government prosecutors far too much power. Judges and juries are supposed to operate as a check on prosecutors, and they cant do that job if nearly every defendant pleads guilty. Too often, prosecutors, like those in the case of Mattis and Rahman, use indictments to extort guilty pleas rather than to achieve justice.

This is, in many respects, a hopeful moment for progress in the criminal-justice system. District attorneys in cities like Philadelphia, Milwaukee, and San Francisco are pulling back from the mindless pursuit of more convictions and longer sentences. Eric Gonzalez, the Brooklyn District Attorney, is also a reformer, which may be a reason that Barrs minions snatched the Molotov-cocktail cases away from him. The Attorney General has expressed nothing but contempt for more civilized approaches to law enforcement. In a speech in February, he attacked the new generation of prosecutors, asserting, These D.A.s think they are helping people, but they end up hurting them. These policies actually lead to greater criminality. This, to put it charitably, is unproven. Reformers have been winning elections around the country not because their constituents want greater criminality but because they recognize that we have incarcerated too many people (and particularly too many people of color) for too long.

As usual, Barr is channelling his boss, who has responded to the George Floyd protests with ugly spasms of race-baiting and bigotry. But, as bad as Trumps invective is on Twitter and elsewhere, Barrs actions are worse, because individuals and communities will be paying the costs for years, or decades, to come.

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The Halted Progress of Criminal-Justice Reform - The New Yorker

Forward progress stopped on Topsy Fire | NevadaAppeal.com – Nevada Appeal

As of 6 p.m. forward progress on a 25-30-acre fire burning between homes and watershed on Topsy Lane.

Set by lightning around 4 p.m. the fire resulted in Topsy Lane east of Highway 395 being closed.

Firefighters say two outbuildings have been lost with damage to one home.

Smoke reduced visibility on Highway 395 for the evening commute.

ORIGINAL REPORT: Air support has been called into help a fast moving brush fire south of Carson City near Topsy Lane.

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East Fork Fire and Carson City Fire Department were called Thursday afternoon about 4:05 p.m. The fire was reported to be ready to jump Topsy Lane at 4:20 p.m. moving away from structures.

Multiple fire engines and brush units are responding , structures are currently threatened.

Traffic is backed up due to construction and fire equipment attempting to access the fire.

At 3:36 p.m., Doppler radar was tracking a strong thunderstorm near Gardnerville.

This storm was nearly stationary, according to the National Weather Service.

Heavy rain with water covering usually dry stream beds and winds in excess of 40 mph will be possible with this storm.

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Forward progress stopped on Topsy Fire | NevadaAppeal.com - Nevada Appeal

There might be progress in a 20-year-old Evansville killing | Webb – Courier & Press

Elizabeth Banister, 18, was found stabbed to death in Evansville on Jan. 20, 2000. Evansville Courier & Press

After decades of frustration, there may be some progress in a 20-year-old Evansville homicide.

Thats according to Sara Stewart, the sister of Elizabeth Banister: an 18-year-old Evansville woman who was found stabbed to death in her near-Downtown apartment just after midnight on Jan. 20, 2000.

Eyewitness News first reported the story Monday night. Stewart later confirmed the news to the Courier & Press as well.

According to Eyewitness, Stewart said a private investigator may have located a possible suspect. Thatperson is reportedly in jail.

Evansville police are aware of the possible suspect, detective Aaron McCormick told the station. Theyre still gathering information.

More: Evansville woman is still trying to solve her sister's murder | Webb

More: It's now been 20 years since this horrible, unsolved Evansville killing | Webb

Elizabeth Banister(Photo: 1998 North High School yearbook)

I interviewed Stewart about her sister back in 2019. She said communication with investigators has dwindled dramatically over the years, to the point where she didnt even know the name of the detective assigned to the case.

There are a lot of cold cases, and I get it: they have a lot of work to do, she said then. But not one cold case is more important than another.

Hordes of unsolved killings hang over Evansville including a horrific slate of homicides in the past few months.

All of them are perplexing in their own way, but the Banister killing is especially sad and bizarre.

The apartment at 254 Washington Ave. was full that night. Friends flooded the place to drink and hang out.

But the crowd thinned by midnight. One person was passed out drunk. Another watched a Matlock rerun. And a third stepped out to use a communal bathroom in a different part of the building.

Around 1 a.m., a friend dipped their head into the apartment to check on Elizabeth. Thats when they discovered a crime scene that has baffled Stewart and investigatorsfor decades.

Elizabeth had been stabbed multiple times in the chest the fatal slash piercing her aorta.

No one in the apartment reported hearing anything strange. The only possible lead came from a neighbor who claimed they spotted an African American male duck out a window and run off into the night.

Somehow, someone slipped into a crowded apartment and killed this young woman without anyone noticing.

According to C&P stories from the time, police interviewed dozens of witnesses. Everyone in the apartment was cleared of any wrongdoing, and any hope of quickly solving the killing dissipated as time slogged on.

Stewart has never given up. Shes spoken with private investigators and started a Facebook group to cull leads.

Shell do anything to solve the killing of her sweet, humble sister, she told me. Elizabeth was a caring, generous person who survived an abusive childhood and emerged as a strong young woman ready to start a new life.

She deserves justice, Stewart said.

I may never find out who killed her. It may continue to be an unsolved case, she told me in 2019. They may find the killer after Im dead. After Im old and gone.

I dont know. But I feel like Im not doing enough.

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Contact columnist Jon Webb at jon.webb@courierpress.com

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There might be progress in a 20-year-old Evansville killing | Webb - Courier & Press

ADA’s 30th anniversary marks progress for disabled Americans, but there’s still work to be done – Scottsbluff Star Herald

WASHINGTON Michael Warners parents were presented with a choice after their baby boy was diagnosed with spastic cerebral palsy.

They could have him immediately institutionalized or raise him at home.

Luckily, they chose the latter,Warner said.

It was just a few years afterward on July 26, 1990 that the Americans with Disabilities Act was signed into law.

That landmark initiative sought to make it easier for Warner and other disabled Americans to stay out of institutional settings and instead be integrated into the broader community.

Warner grew up in Omaha and still lives in the city. He describes himself as a member of the first generation to come of age under the ADA, which he credited with allowing him a public school education alongside his peers.

My ability to live my life as independently as possible is directly correlated with the passage of the ADA, Warner said. I wouldnt be able to live my life as effectively as I have without it.

Advocates have been celebrating the ADAs 30th anniversary this week with events hailing the progress achieved and highlighting areas where work remains to be done.

Former Sen. Tom Harkin, D-Iowa, has been a fixture of the commemorations as the chief sponsor behind the legislation. Harkin pushed for the ADA after witnessing the discrimination faced by his deaf brother.

Harkin said he saw how those with disabilities were subjected to demeaning language like cripple and moron and shut out of society.

For a person with a disability, it was a life of segregation and separation from their family and their friends and their community, Harkin said of the country before 1990. It was a life of hurtful language that you would hear all the time. And it was a life, even among the most well-meaning of people, it was a life of pity and patronizing attitudes. Life was limiting in so many ways to a person with a disability before the ADA.

The new law meant commercial buildings with accessible entryways, sidewalks with curb cuts, buses with wheelchair ramps and restrooms that disabled people could use.

More broadly, though, it helped shift the American mindset to regard inclusion and accommodation as the norm, rather than the exception.

Weve come a long way. Weve made a lot of good changes in society, Harkin said. A lot of attitudes have changed about what people with disabilities are capable of doing.

Barriers still remain for the disabled and one of the biggest challenges is economic self-sufficiency. Harkin noted that statistics show the lack of employment among disabled people has improved little over the past 30 years.

Thats a blot on our national character, Harkin said. Weve got to do a better job on that.

Warner, for example, says he has never held a full-time job but would like to. He graduated from Northwest High School in Omaha in 2005 and recently received an associate degree from Metropolitan Community College. Once the coronavirus pandemic has faded, he hopes to go back to school for a bachelors degree and has talked about working as a disability consultant to companies alongside his work as an advocate and activist.

But he said some employers are hesitant to hire people with disabilities.

They dont know how they would handle disabled employees, especially if were talking about a physical limitation that is somewhat severe. And that is an issue, Warner said. We need to get past this stigma of not understanding or not knowing how to best utilize employees that might have a disability.

Another Omahan, Rick Rodgers, was injured in a 2001 work accident in which he was thrown off the back of a tractor. The resulting surgeries left him with numerous screws and a steel rod in his body.

Im a cross between Frankenstein and an erector set, he joked.

Rodgers needs a wheelchair much of the time because of the nerve damage and pain, but he said many Omaha buildings remain difficult to get into even today, and the ramps on city buses dont always work.

Finding a job is also an issue. Rodgers went back to college and got certified to work on computers but he says potential employers dont want to be liable for his medical issues.

I cant get any companies to hire me, mainly because of my health, he said. That needs to be addressed.

Warner noted that many disabled individuals also worry about taking a full-time job because that can mean losing public benefits such as health insurance or Social Security payments.

Im glad for what we do have, as far as being able to be out in the community and gain access to commerce, but I do believe there are further steps that could be taken, Warner said.

Improving work opportunities for the disabled has been a focus for Harkin since he retired from the Senate. He has urged companies to overhaul training programs and do whatever else is necessary to increase their hiring of disabled Americans.

Congress could help the situation by passing legislation that would address the issue of disabled individuals losing benefits if they find full-time employment, he said.

Of the various ADA anniversary events Harkin joined this week, he said the most fun was a plane ride Friday with the first armless pilot, Jessica Cox, at the controls.

The two met through her advocacy work on the United Nations Convention on the Rights of Persons with Disabilities treaty, which they both continue to push.

Ive been able to see around the world what people with disabilities experience and how they are not protected, Cox said.

Harkin is a lifelong aviator himself, so they quickly bonded over their love of planes and Cox offered to take him up with her.

Years went by before they were able to make it happen, but Friday they lifted off in a 1946 Ercoup plane from an airport in Frederick, Maryland.

After the brief flight, Cox talked about being in first grade when the ADA went into effect and how she quickly noticed differences, from accessible entryways to restrooms. She even got a slanted desk that allowed her to write with her feet.

For his part, Harkin said that Cox is an inspiration and that the landing she executed on Friday was among the finest hed ever seen.

I was so enthralled by watching her and seeing how good she was, Harkin said. She knows how to handle an airplane.

We're always interested in hearing about news in our community. Let us know what's going on!

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ADA's 30th anniversary marks progress for disabled Americans, but there's still work to be done - Scottsbluff Star Herald

Centering Equity in the Future-of-Work Conversation Is Critical for Women’s Progress – Center For American Progress

The ongoing discussion about the future of work has focused much-needed attention on how best to prepare for the changing nature of the workforce and the workplace. This conversation has taken on added importance with the onset of the coronavirus pandemic that has led to skyrocketing unemployment in the United Stateswhich has disproportionately affected women, particularly women of colorand devastated the economy at levels not seen since the Great Depression. The pandemic has placed new strains on workplaces already hampered by old problems, not the least of which include the persistent barriers that undermine womens economic standing and employment opportunities.

The conversation about the future of work has largely centered on readying workers by discussing the new skills they may need to acquire, jobs that are expected to grow, and how emerging technologies may change workplace operations and the nature of work. However, it is equally important to focus on preparing workplaces for the future by transforming work environments so that all workers have the best chance of success and can participate to their fullest potential.

For women, these transformed workplaces must be free of the barriers and biases that have been used for years to limit their opportunities, undermine their advancement, and depress their wages. The workplace of the future must view womenand the diverse experiences they bring to the tablenot as workers who fall short of a preferred norm but as workers who are valued and recognized for their contributions. This means a workplace where workers can take time off for their familys medical or caregiving needs without adversely affecting their job or advancement prospects. It means a workplace that is rooted in equity and free of discrimination and harmful stereotypes about womens skills, work ethic, attitude, leadership abilities, or intellect. It means a workplace where pay gaps are nonexistent and women are not funneled into a narrow selection of jobs with lower wages and little mobility. It means a workplace culture that is inclusive of diverse perspectives and diverse leadership, embraces collaboration among workers and management at all levels, and supports the individual and collective power of workers to create an environment responsive to their needs.

The task of workplace transformation for the future, however, must also be informed by understanding the successes and failures of the past. Having both a broad historical and contemporary perspective is particularly important to ensure womens continued workplace progress and to address longstanding disparities in pay, career advancement, and opportunities that have impeded womens progress and undermined their overall economic stability. This wide view makes clear that the pursuit of equity through measures aimed at leveling the playing field, countering persistent biases, and removing sex-based barriers to employment is essential to opening new doors for women and changing attitudes about their abilities.

While working women in the United States have made significant gains, including expanded job opportunities and legal protections to promote equality and combat discrimination, the path to workplace success for women has been shapedand often constrainedby their status as women.

Biases around gender, race, ethnicity, and class have resulted in the exclusion of women from jobs and have curtailed their workforce participation throughout the nations history. These barriers affected both white women and women of color, although the experiences of these groups were often very different. Historically, menprimarily white, cisgender menhave played a dominant role in shaping the structure, operations, and overall culture of American workplaces by virtue of holding the most powerful and highly paid jobs.

Women who worked in paid jobs well into the 20th century had limited employment options because many occupations were, in practice, not open to them. Additionally, white women were less likely to be engaged in paid work outside of the home than women of color, in part because of a racial and ethnic hierarchy that frequently afforded white women a more privileged societal and economic status. For example, a little more than 16 percent of white women worked for pay in 1890 compared with almost 40 percent of nonwhite women. White women who worked for pay outside of the home were primarily single women until the 1920s, when more white married women gradually began moving into the paid workforce.

During this same time period, working women of color were faced with the combined effects of race, gender, and ethnic biasesknown as intersectional discriminationand were relegated to the lowest-paid positions. For Black women, entrenched racism rooted in the nations painful history of slavery and racial oppression meant that they were expected to work in jobs with few benefits or protections, with little regard given to their working conditions or their personal or family needs. Many were limited to domestic work, caregiving work, or other service jobs. Immigrant and Native American women were also subjected to oppressive tactics that reduced their job options, primarily working as laborers, domestic workers, and service workers. Much of this work by women of color, although essential to the care and support of families, was not as valued or respected as other types of paid work. Domestic and caregiving work, whether paid or unpaid, was often dismissed as mere womens work and deemed less important.

Womens progress in moving beyond the historical limits placed on their economic participation did not occur by chance: It required intentional change in laws, workplace structures and practices, and workplace culture to create spaces that are more equitable, fair, and welcoming. These gains were grounded in the equality principles established at the nations founding, interpreted and expanded to encompass a commitment to equal opportunity and equal justice for all women. The focus on greater equity required a shift toward seeing women as deserving of equal opportunity to participate fully in the economy and determine their own direction. This shift, one that occurred gradually over time, was not merely an act of beneficence toward women. Rather, it reflected an emerging recognition of the benefits of womens workforce participation, from increased economic security for families to improving business outcomes for employers to helping boost the nations annual gross domestic product.

The passage of landmark laws such as the Equal Pay Act of 1963, Title VII of the Civil Rights Act of 1964, and the Pregnancy Discrimination Act of 1978 established critical protections to prohibit various forms of sex discrimination and ensure that women were not denied opportunities or treated unfairly solely because of their sex. These measures were bolstered by later laws, including the Americans with Disabilities Act passed in 1990, which extended additional anti-discrimination protections to women and other workers with disabilities. The 1993 Family and Medical Leave Act (FMLA) broke new ground by enabling eligible workers to take up to 12 weeks of unpaid leave for family or medical emergencies, helping to address a form of discrimination mostly faced by women who need time off to care for their families. The Supreme Court also played a role interpreting key protections, such as those available under Title VII, to cover different forms of sex discrimination including sexual harassment and, most recently, discrimination aimed at LGBTQ workers.

The implementation of these protections required a commitment to robust enforcement of the law. The U.S. Equal Employment Opportunity Commission (EEOC), established by the 1964 Civil Rights Act and launched in 1965, enforces the vast majority of the protections against sex discrimination in employment; one exception is the FMLA, which is enforced by the U.S. Department of Labor. The EEOC has been instrumental in using its investigatory and litigation powers to enforce womens legal rights and help expand womens employment options. This enforcement remains pivotal to womens progress. Nearly one-third of the estimated 414,235 charges filed with the EEOC from fiscal year 2015 to fiscal year 2019 included charges alleging sex discrimination. These enforcement efforts complement the work employers should also be undertaking to tackle persistent disparities, eliminate systemic practices that exclude women, and transform workplace culture.

Even with the important gains women have made, too many workplaces are still marred by persistent inequities, outdated attitudes, and entrenched biases. These problems translate into adverse employment outcomes, including disparities in womens earnings, job opportunities, job mobility, and advancement opportunities. For example, researchers have found that among transgender workers, trans women are more likely to report losing a job because of their gender identity or expression than trans men or nonbinary individuals. Women also continue to experience a stubborn pay gap: Women working full time, year-round earn 82 cents for every dollar earned by male full-time, year-round workers. And this gap is even more pronounced for many women of color: Black women earn 62 cents, Latinas earn 54 cents, Native American women earn 57 cents, and Asian American women earn 90 cents for every dollar earned by white men. Researchers also have found pay disparities among trans workers, with one study finding that the earnings of trans women workers surveyed fell by nearly one-third after their gender transition. Over the course of a lifetime, these gaps can add up to hundreds of thousands of dollars in lost earnings for women.

Women also are underrepresented in leadership and in the most senior jobs in Fortune 500 companies, with women of color experiencing the sharpest leadership disparities. Even with a record-high number of 37 women as Fortune 500 CEOs in 2020, the milestone represents just 7.4 percent of the total number of CEOs. Furthermore, only three of these women are women of color, none of whom are African American or Latina. This lack of opportunity not only deprives women of higher earnings and greater economic security but also can affect the business bottom line. Research increasingly shows that businesses with greater gender and ethnic diversity at the executive level report better financial performance than industry averages.

Instilling gender equity practices requires a range of intentional interventions, including six areas for action: strong legal protections, robust enforcement mechanisms, modern workplace policies to address work-family needs, broad worker supports, deep structural and cultural change, and a strong commitment to focusing resources on workers who face the sharpest disparities.

Strengthening legal protections can fill gaps where additional support is needed and help establish a baseline measure of employer accountability. Adopting federal proposals to close longstanding loopholessuch as the any factor other than sex defense that has enabled employers to justify pay disparities without having to show a business necessity and job rationaleis critical to thwart efforts to undermine equal pay enforcement. Another potential legal improvement could replicate progress made in states such as California, which prohibits the misuse of a workers salary history when making hiring decisionsa practice that poses an obstacle to equal pay. Exploring new measures to protect workers with caregiving responsibilities from discrimination, particularly in the midst of the current pandemic, is also a legal strategy policymakers should pursue to counter sex discrimination on the job.

Additionally, substantial investments in the full range of federal enforcement mechanisms are needed to ensure agencies have the staffing, investigatory tools, and jurisdictional authority they need to achieve compliance with the law. The EEOC, the U.S. Department of Labors Office of Federal Contract Compliance Programs (OFCCP), and the U.S. Department of Justice all play a role in ensuring that workplaces in the public and private sector are free of discrimination, but more progress is needed. Policymakers should increase funding to double the available resources for federal enforcement efforts and strengthen investigatory tools such as enforcement officials access to employers pay data on an annual basis. Agencies should have the resources to respond rapidly to situations like the current pandemic and take action in real timefor example, by challenging instances of sex discrimination when employers decide not to hire or rehire women workers because they have small children or may need time off in the future.

Pushing for better workplace policies to help modernize workplaces and respond to workers diverse needs is also critical to achieving greater workplace equity. As the pandemic has painfully demonstrated, the lack of strong work-family policies such as paid sick days, paid family and medical leave, and access to flexible scheduling or telework has left too many workers without the necessary supports to navigate work-family emergencies.

Several companies, including Microsoft and Zillow, revamped their policies in response to the coronavirus crisis to provide workers with more flexibility to work from home. Such policies are particularly important to address potential discrimination aimed at women workers, who tend to assume the majority of caregiving responsibilities in their families. But higher-wage workers are far more likely to have access to such work-from-home options than lower-wage workers, and many jobs, such as home care or grocery stores jobs, are not designed for remote work. Leisure and hospitality occupationswhich comprise a disproportionately high number of women, particularly women of colorare the least likely to have telework options, with less than 10 percent of workers in the industry able to telework. Access to paid leave and other supports is even more important for these workers. Yet despite the passage of emergency COVID-19 provisions to provide more workers with paid leave, more than 100 million workers may be exempt from these protections. Some employers have expanded their paid leave policies in response to the pandemic, but many workers continue to struggle with how to care for sick family members without putting their jobs at risk.

These actions must be coupled with measures directly focused on disrupting power imbalances, workplace structures, and longstanding stereotypes and biases used to perpetuate inequity and hold women back. Supporting efforts to bolster worker powerincluding removing barriers to collective organizing, partnering with worker organizers to respond to employment violations, and providing resources for worker advocatescan help address problems in real time. For example, worker-led initiatives to combat sexual harassment among janitorial workers and farmworkers are models that have proven effective in helping to improve working conditions for many women in these sectors.

Employers must also closely examine their own workplaces to ensure that they are free of discrimination, from individual interactions to operational structures and practices. This means investing in ongoing, comprehensive training to counter implicit biases and pervasive, harmful stereotypes about women, such as mischaracterizing Black women as angry, Latinas as oversexualized, or Asian American women as submissive. It could also involve undertaking internal analyses and climate surveys to uncover differences in employee experiences, promotion rates, or pay practices. For instance, Salesforcea company that provides customer relationship management servicesbegan to take steps in 2015 to analyze their worker compensation. Over the course of the next four years, the company spent more than $10 million to correct gender pay disparities. In 2016, more than 100 companies joined an equal pay pledge launched by the Obama administration, committing to analyze their compensation and identify pay disparities within their workforces on an annual basis.

All of these strategies can be used to inject more equity and fairness into workplaces and, in doing so, create environments where women are more likely to be successful.

The ability of women across race and ethnicity, income level, disability status, and gender identity to succeed at work in the future will depend on the scope and depth of efforts to remove longstanding barriers and expand opportunities. This work not only should encompass the full range of interventions to improve legal protections, enforcement tools, workplace policies and structures, and worker supports, but also should prioritize several key measures to help drive transformational change and promote equity in the workplace.

Employers should undertake an equity assessment of their workplaces to identify disparities across measures including race, gender, ethnicity, disability, and LGBTQ status. These assessments should be used to pinpoint problems and help establish concrete, measurable targets where progress is needed. For example, women are less likely than men to advance into the most senior organizational roles, and women of color are less likely to advance into senior positions or management than their white female counterparts. Employers should adopt specific goals and targets to increase these numbers over time.

An assessment tool should utilize different types of measuresfrom hiring and promotion rates, to demographic differences in workplace morale, to overall numbers of women and people of color in leadershipand explore the different factors that determine success in individual workplaces. To help ensure that every assessment is robust and thorough in scope, research funding could be directed to support the development of a model assessment tool or template that an employer could use as a guide to conduct an internal equity assessment. Furthermore, the adoption of new rules to promote greater accountability and transparencysuch as the disclosure of salary ranges, pay gaps, and pay datamay help reduce disparities and encourage quick remedial action by employers. Future workplaces must use equity-based measures to evaluate overall quality and preparedness for the years ahead.

Workplaces of the future must be incentivized to embrace a more holistic understanding of work and family and value the full range of experiences that women and all workers bring to the table. This means centering the experiences of women to gain a deeper understanding of the harshest challenges and obstacles facing many women of color, low-income women, transgender women, women with disabilities, and immigrant women. Many low-income women, for example, are less likely to have access to vital work-family supports: Only 47 percent of low-wage workers have access to paid sick days compared with 90 percent of the highest-wage workers. In addition, Black and Latinx workers are less likely to be able to telework. Black women and Latinas are more likely to be single heads of household than their white counterparts, meaning that the lack of available child care may pose additional barriers as they try to return to work amid the ongoing pandemic. Employers ability to access lucrative opportunities, such as being awarded a federal contract, should be conditioned in part on how well they address these diverse needs through baseline workplace benefits such as paid leave and access to emergency child care.

Although there is no sure-fire remedy for eliminating bias and research shows mixed results from routine diversity training programs, there are strategies that have been shown to be effective. Researchers have found that efforts to increase diversity and inclusion have a greater likelihood of success if they are part of an ongoing program of learning rather than a one-time intervention or one-size-fits-all solution. Such efforts should go beyond solely training workers about legal requirements and seek to bridge perspectives, reverse roles, and understand power imbalances. This could include undertaking regular surveys of workplace climate; initiating trainings on implicit bias tailored to a particular work environment; and reevaluating reporting mechanisms, evaluation measures, promotion practices, and processes for pay decisions.

For example, when Starbucks experienced several high-profile incidents involving racial profiling of Black customers, the company initiated a series of anti-bias trainings over the course of one year along with other measures to address internal issues such as pay equity and greater racial and gender diversity in hiring. Other efforts that have shown promise include initiatives that bring workers and management together on a task force or committee to work collaboratively on programs to drive change. More recently, in response to the national reckoning on systemic racism spurred by a spate of killings of African Americans by police, leaders of organizations and institutions increasingly have been called upon to examine their internal structures and prioritize equity to achieve systemic change. Ongoing investments in research and study to identify best practices should be a focus of future of work efforts.

Future workplaces must focus on ways to disrupt power imbalances that perpetuate disparities and discrimination. Minimizing how power can be misused within a workplace and diversifying who holds the power to drive decision-making are important steps toward establishing a greater sense of fairness and collective engagement. This can include collective efforts to raise the minimum wage or grant overtime to domestic workers through a domestic workers bill of rights. New York, California, and Hawaii are among the states that have adopted these types of stronger labor protections, but enacting legislation at the national level would help protect more workers across the country. Addressing power dynamics can also include creating more opportunities for collaborative decision-making to foster equity and inclusion among staff at different levels. Workplace transformation often requires an intentional focus on changing the balance of power to establish a shared set of values and commitment to equity across an organization.

The future of work must include efforts to bolster enforcement mechanisms to reach a broader number of employers and foster a workplace culture where equity and accountability measures are fully integrated into regular workplace practices. This means giving enforcement agencies more resources to increase their capacity to provide assistance through trainings, webinars, or publication of model policies. These resources are also needed to increase staffing at enforcement agencies to conduct more investigations and reviews of employer practices. For example, the OFCCP conducts compliance reviews of less than 5 percent of the more than 120,000 individual establishments under its jurisdiction. Additional resources could help increase the number of reviews conducted, including targeted reviews of barriers within senior leadership levels, referred to as corporate management compliance evaluations or glass ceiling reviews. The Trump administration has repeatedly sought to reduce funding for key enforcement agencies, proposing cuts that would further deplete staffing and impair the ability of these agencies to keep up with current caseloads and investigations. Increasing budgets by 25 percent for each of the next four years would provide a new infusion of resources and allow for vigorous enforcement.

Discussions about the future of work in the United States must focus on creating a new normal around success that is grounded in a commitment to equity as a foundational principle and core value. It is essential that new jobs of the future include this focus on equity; without it, women will continue to face disparities in the workplace. This concerted effort requires centering those whose experiences are often treated as an afterthoughtwomen of color, women with disabilities, and LGBTQ women. Employers and policymakers alike must implement intentional corrective strategies specifically focused on how to inject and embed equity practices into workplace systems and structures to erode the barriers holding women back and avoid perpetuating problems into the future. Creating an equitable future also means making real a narrative about work that values the diverse experiences and skills of all womenindeed, all workersand prioritizes policies to counter longstanding disparities and create opportunity.

Jocelyn Frye is a senior fellow with the Womens Initiative at the Center for American Progress. Her work focuses on improving womens employment opportunities and economic security with a particular focus on the experiences of women of color.

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Centering Equity in the Future-of-Work Conversation Is Critical for Women's Progress - Center For American Progress

FOTAS: 11 years of progress at the Aiken County Animal Shelter – Aiken Standard

On July 29, 2009, the South Carolina secretary of state officially approved FOTAS as a charitable nonprofit organization dedicated to the care of the homeless, abandoned and abused animals consigned to the County Shelter, kicking off the beginning of an extraordinary public/private partnership with the county and a new, comprehensive approach to caring for homeless animals. It was a massive undertaking. At the time, over 6,000 animals a year passed through the doors of the countys tiny, antiquated shelter. Only 5% made it out alive.

All of that has changed in the past 11 years. With the opening of the new shelter in 2014, the FOTAS/county partnership solidified and blossomed. FOTAS volunteers are an integral part of the shelters operations. (It is estimated that FOTAS volunteers provide the equivalent of 10 full-time positions.) FOTAS donations supplement the shelters budget and programs and provide supplies such as leashes, toys, flea and tick prevention, and medicine for heartworm-positive dogs. FOTAS has created a network of transfer partners in other parts of the country (where kennels are empty because everyone fixes their pets) where we send dogs (and pay the incurred transport costs) who could not find homes locally. The transfer program saves thousands of animals every year.

We also attack the problem of overpopulation of homeless pets. FOTAS supplements the countys spay/neuter financial assistance program for county residents who need it, as well as funds to support the TNR (trap-neuter-return) program to address the problems of community cats. We hire a mobile spay/neuter van to go to hot-spot areas around the county (the FIDO Fix-a-Pet program) to provide free spay/neuter surgeries for citizens who need financial assistance.

Our Home-to-Home program allows folks who can no longer care for their pets to use the power of the FOTAS social media to find homes without subjecting their beloved pets to the trauma of surrender to the shelter. (It's been a huge success during the COVID-19 crisis!) FOTAS works with Animal Control to provide dog houses and humane runners for dogs who are tethered to chains, as well as dog food and other supplies to help folks in a bind.

FOTAS also helps with the improvement of the physical facilities at the shelter. In addition to funding the medical wellness and isolation pod for animals with curable infectious ailments, plans are currently underway for a building that will house two, much needed adoption rooms and a training area.

In 2017, FOTAS was one of 10 (out of 14,000) charitable organizations to be awarded the Angel Award by the secretary of state, which recognizes the most efficient and effective nonprofits in the state. Plus, for the second year in a row, FOTAS and our signature event, the Woofstock Doggie Derby Day, received the Aiken Standard's Aiken Choice Best of Aiken Award.

We have managed to do all of this with only one full-time staff person and an army of volunteers. Has it worked? You bet it has. For the past two years, FOTAS and the county achieved their goal of not having to euthanize any adoptable pet.

None of this would have been possible without you, the generous Aiken community, who have donated your time and money and welcomed shelter animals into your hearts and homes.

Thank you and God Bless. Stay safe.

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FOTAS: 11 years of progress at the Aiken County Animal Shelter - Aiken Standard

Hamilton frustrated by lack of diversity progress; calls on Todt to be ‘a leader’ – GPfans

Lewis Hamilton does not believe any progress has been made in Formula 1 since he raised awareness over the lack of diversity in the sport at the start of the season.

The topic has become a political hot potato in F1, with Hamilton's outspoken comments and his pledge towards the Black Lives Matter campaign sparking a wide-ranging debate, along with the action of taking a knee.

While there was initial support from F1 and the FIA, notably the instigation of the #WeRaceAsOne engagement, Hamilton has been dismayed by what has since transpired.

It recently led to him criticising F1 and Grand Prix Drivers' Association director Romain Grosjean, who was in turn defended by Haas team principal Guenther Steiner.

Asked as to whether he was proud of the progress made, or frustrated and disappointed given the actions of certain individuals, Hamilton replied: "We haven't made any progress.

"We've said things, there have been statements released and we've made gestures, such as kneeling, but we've not changed anything, except some of our awareness."

It appears Hamilton is irritated by the lack of a reaction from the other nine F1 teams beyond his own in Mercedes.

"I am definitely encouraged by our team and those in Formula 1 asking 'What more can we do? How can we do it better?'" added Hamilton.

"It's about communication, so I'll get back on a call with Formula 1 and see where they are, where they are feeling confused, and whether they're feeling the pressure. I'd love to know what Jean and Chase think, and what the organisation thinks moving forward.

"But there is no progress yet. So far it's been visible, but there are nine teams - I think there is one I've spoken to which is working in the background, but there are no other teams I know of that are being held accountable, or hold themselves accountable."

While the six-time F1 champion has been doing all he can to promote awareness, he feels it needs someone in authority to issue a call to arms from the rest of F1, such as FIA president Jean Todt.

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Hamilton frustrated by lack of diversity progress; calls on Todt to be 'a leader' - GPfans

BioNTech COVID-19 Progress, And Other News: The Good, Bad And Ugly Of Biopharma – Seeking Alpha

BioNTech reports positive COVID-19 vaccine data with Pfizer, receives $2 billion order from US Govt

BioNTech SE (BNTX) reported positive early data for its COVID-19 vaccine candidate, BNT162b1. The company is collaborating with Pfizer (PFE) for developing this vaccine candidate. BNT162b1 is a lipid nanoparticle formulated, nucleoside-modified messenger RNA encoding a SARS-CoV-2 receptor binding domain (RBD) antigen.

Phase I/II of the study is an open-label, non-randomized, non-placebo-controlled, dose-escalation trial. It is being conducted in Germany and involves 60 healthy participants aged between 18 and 55 years. Out of these, 12 participants were given 1g, 10g, 30g or 50g of BNT162b1 each on day one and day 22. The remaining 12 participants were administered with a single injection of 60g.

The data showed that the drug candidate induced high, dose-dependent SARS-CoV-2 neutralizing titers and RBD-binding IgG concentrations. These results were found after the administration of second dose. It showed a concurrent stimulation of high level CD4+ and CD8+ T cell responses against the SARS-CoV-2 RBD as well. Overall BNT162b1 was found to have a manageable tolerability profile as no serious adverse events were reported.

The data did not show any clear dose level dependency of the T cell response between 1g to 50g, suggesting that low mRNA dose levels may have induced and expanded T cells. zlem Treci, CEO of BioNTech said, "The preliminary data indicate that our mRNA-based vaccine was able to stimulate antibody, as well as T-cell responses at remarkably low dose levels. We believe both may play an important role in achieving effective clearance of a pathogen, such as SARS-CoV-2." He added that the data from German study is in line with the data obtained from US study cohort.

The company plans to use the data collected from these studies to determine a dose level. BioNTech will also use the data from other preclinical and clinical studies. Further, the data will also be used for selecting vaccine candidates for a Phase IIb/III safety and efficacy trial, which may enroll up to 30,000 healthy volunteers.

The company's successful trial is followed up by a mass order for the vaccine candidate placed by the United States government. According to the reports, the US government has ordered up to 100 million dosage for $1.95 billion. The payment will be made once the vaccine is delivered, post regulatory approval. The US government may decide to opt for up to additional 500 million doses.

Further, European Union is also believed to be in fray for the vaccine candidate. However, European Union declined to individually identify the firms it is currently in talks with. The United States government has entered the deal through its Department of Health and Human Services and the Department of Defense. The government's Operation Warp Speed aims to begin delivering 300 million doses of a vaccine for COVID-19 in 2021.

The BNT162 program is based on BioNTech's proprietary mRNA technology. Pfizer is supporting the program through its global vaccine development and manufacturing capabilities. BioNTech will hold all trademarks for the potential product and has the global market authorization. The Pfizer/BioNTech vaccine development program is evaluating at least four experimental vaccines, each with a unique blend of messenger RNA (mRNA) format and target antigen.

AxoGen Inc. (AXGN) reported the conclusion of its enrollment for Phase 3 pivotal RECON clinical study. The company has enrolled 220 participants in the trial. The protocol for the trial comprises one year follow up assessment as well as three-month visit window. The last patient enrolled is expected to finish the study no later than October 2021.

RECON clinical study or Comparison of Processed Nerve Allograft and Collagen Nerve Cuffs for Peripheral Nerve Repair is a multicenter, evaluator blinded and randomized clinical study of nerve cuffs and Avance Nerve Graft evaluating recovery outcomes for the repair of nerve discontinuities. The study aims to test non-inferiority between the static two-point discrimination outcomes for nerve cuffs and Avance Nerve Graft.

AxoGen expects the preliminary data to be available during the second quarter of 2022. Karen Zaderej, chairman, CEO, and president of AxoGen, "Completing enrollment for the RECON Study is a critical step in transitioning our Avance Nerve Graft from classification as a section 361 HCT/P tissue product to a section 351 biological product." The company will likely file the BLA for the drug candidate in 2023.

Avance Nerve Graft is a biologically active off-the-shelf processed human nerve allograft. It is mainly used for bridging the gap between severed peripheral nerves without the comorbidities associated with a second surgical site. The product is available in wide range of lengths and diameters. Avance Nerve Graft received a Regenerative Medicine Advance Therapy tag from the FDA in September 2018. The designation allows the candidate to go through a streamlined approval process for regenerative medicine technologies. It also provides for frequent informal meetings with the FDA.

InflaRx (IFRX) announced its plan to continue development of IFX-1 for treating severe COVID-19 induced pneumonia. The company is looking to start a randomized, placebo-controlled, double-blinded Phase III trial spread across multiple sites in the US, Europe, South America and potentially other regions. The plans are subject to regulatory approvals.

The Phase III study is expected to enroll nearly 360 patients who are early intubated and are critically ill. An interim analysis is planned to be carried out once 180 patients are enrolled. There is also provision for an early stop of efficacy or futility. The primary endpoint for the trial is 28 day all cause mortality. Other proposed key endpoints include evaluation of organ support and analysis of disease improvement on the ordinal scale.

The Phase II part of the study assessed IFX-1 treatment plus best supportive care compared to best supportive care alone for up to 28 days. That phase enrolled 30 patients and was randomized. Dr. Korinna Pilz of InflaRx noted, "Data from the initial exploratory Phase II part of the study in patients with severe COVID-19 induced pneumonia suggested a positive impact of IFX-1 treatment on the all-cause mortality rate and other endpoints." The IFX-1 treatment arm had shown 13 percent 28-day all-cause mortality rate.

IFX-1 is a first-in-class monoclonal anti-human complement factor C5a antibody. It works by blocking the activity of C5a. It also shows high selectivity towards its target in human blood. The drug candidate is currently being assessed for a wide range of indications including Pyoderma Gangraenosum, Hidradenitis Suppurativa and ANCA-associated vasculitis among others.

InflaRx is a clinical-stage biopharmaceutical company. It is mainly engaged in discovering and developing specific and potent inhibitors of C5a using its proprietary anti-C5a technology.

Thanks for reading. At the Total Pharma Tracker, we do more than follow biotech news. Using our IOMachine, our team of analysts work to be ahead of the curve.

That means that when the catalyst comes that will make or break a stock, we've positioned ourselves for success. And we share that positioning and all the analysis behind it with our members.

Disclosure: I/we have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

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BioNTech COVID-19 Progress, And Other News: The Good, Bad And Ugly Of Biopharma - Seeking Alpha

ADA’s 30th anniversary marks progress for disabled Americans, but there’s still work to be done – Omaha World-Herald

Finding a job is also an issue. Rodgers went back to college and got certified to work on computers, but he says potential employers dont want to be liable for his medical issues.

I cant get any companies to hire me, mainly because of my health, he said. That needs to be addressed.

Warner noted that many disabled individuals also worry about taking a full-time job because that can mean losing public benefits such as health insurance or Social Security payments.

Im glad for what we do have, as far as being able to be out in the community and gain access to commerce, but I do believe there are further steps that could be taken, Warner said.

Improving work opportunities for the disabled has been a focus for Harkin since he retired from the Senate in 2015. He has urged companies to overhaul training programs and do whatever else is necessary to increase their hiring of disabled Americans.

Congress could help by passing legislation that would address the issue of disabled individuals losing benefits if they find full-time employment, he said.

Sen. Tom Harkin participated in events this week marking the 30th anniversary of the ADA, including a plane ride on Friday. The first armless pilot, Jessica Cox shown with him in the plane was at the controls.

Of the various ADA anniversary events Harkin joined this week, he said the most fun was a plane ride Friday with the first armless pilot, Jessica Cox, at the controls.

The two met through her advocacy work on the United Nations Convention on the Rights of Persons with Disabilities treaty, which they both continue to push.

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ADA's 30th anniversary marks progress for disabled Americans, but there's still work to be done - Omaha World-Herald

Progress still hampered by battles on the fringes – McMinnville News-Register

Wednesday night, Portland Mayor Ted Wheeler, also the citys police commissioner, was simultaneously being gassed by federal agents and berated by protesters cursing his name, labeling his appearance at the 56th night of protest nothing more than a photo opportunity.

The videos of federal agents dispatched by the president gassing moms and clubbing veterans simply wanting to hold a conversation are abhorrent. While the agents have legal standing to protect the federal courthouse, the tactics administered have rightfully sparked a national outcry against a militarized federal government engaging in street clashes against its citizens. It is indeed a radical response from the U.S. Executive Branch, and likely more about politics than law and order as an election nears.

But its also not a surprising occurrence in Portland, where fringe activists have historically been allowed too much leeway to ruin the pure demonstrations for First Amendment rights amid honest attempts at progress.

To quote from a 2017 editorial in this newspaper:

Whether its Republicans on the right or Democrats on the left, allowing the most radical elements of their bases to compromise their principles and mute their voices is repugnant. It helps tighten the grip of raw partisanship, thus serving to thwart reasonable policy initiatives. ...

But when black-masked anarchists infiltrated the otherwise peaceful Portland demonstrations to pelt police, set blazes, smash windows, snarl traffic and engage in random acts of mayhem, organizers were more critical of the police for restoring order than the anarchists for disrupting it. ...

The anarchists were aided and abetted by then-Mayor Charlie Hales, who established a virtually unmatched record of ineptitude during his mercifully brief tenure. They got another boost when the district attorneys office dismissed charges against virtually all the 113 arrested.

Mayoral successor Ted Wheeler, displaying an equal lack of fortitude, allowed the anarchist fringe to bring city council meetings to a grinding halt for weeks with ceaseless demands for the police chiefs ouster. And it took nothing more than an anonymous threat for Portland anarchists to force cancellation of this years 82nd Avenue of Roses Parade.

It should have come as no surprise when anarchists began tossing Molotov cocktails, setting bonfires, defacing storefronts, shattering windows and pelting police again during the union movements annual May Day Parade, staged May 1 in Portland. After all, they openly recruited participants on social media sites.

But the response from the self-proclaimed voice of the American worker was, distressingly, a condemnation of the police rather than the bomb-throwers who spoiled the party and soiled the cause.

Those following the 50-plus days of protests in Portland this summer know they have been mostly peaceful and lawful. The righteous indignation of systematic racism and police brutality is warranted and deserving of cognitive discourse leading to legislation.

But the ongoing inability or unwillingness on both sides to filter extremist views has lead to a fictitious narrative, to the point where all cops are bastards and hundreds of moms wearing yellow are nothing more than Antifa in a new outfit.

With a subsection of protesters and a president eager to fan the flames of the ongoing urban warfare, as Wheeler described what he felt Wednesday night, it is difficult to find hope in positive reconciliation. But find hope, we must.

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Progress still hampered by battles on the fringes - McMinnville News-Register

Forward progress stopped on Topsy Fire – The Record-Courier

As of 6 p.m. forward progress on a 25-30-acre fire burning between homes and watershed on Topsy Lane.

Set by lightning around 4 p.m. the fire resulted in Topsy Lane east of Highway 395 being closed.

Firefighters say two outbuildings have been lost with damage to one home.

Smoke reduced visibility on Highway 395 for the evening commute.

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East Fork Fire and Carson City Fire Department were called Thursday afternoon about 4:05 p.m. The fire was reported to be ready to jump Topsy Lane at 4:20 p.m.

Multiple fire engines and brush units are responding , structures are currently threatened.

Previous stories

At 3:36 p.m., Doppler radar was tracking a strong thunderstorm near Gardnerville.

This storm was nearly stationary, according to the National Weather Service.

Heavy rain with water covering usually dry stream beds and winds in excess of 40 mph will be possible with this storm.

At 3:36 p.m., Doppler radar was tracking a strong thunderstorm near Gardnerville.

This storm was nearly stationary, according to the National Weather Service.

Heavy rain with water covering usually dry stream beds and winds in excess of 40 mph will be possible with this storm.

Locations impacted include Johnson Lane and the Fish Springs area.

Excerpt from:

Forward progress stopped on Topsy Fire - The Record-Courier

Coronavirus (MN): Gov. Walz Announces Progress In Long-Term Care Battle Plan, But Says Theres Still More Work To Do – WCCO | CBS Minnesota

MINNEAPOLIS (WCCO) Minnesota Gov. Tim Walz, along with state health leaders, announced Tuesday that progress has been made since the long-term care battle plan was implemented in early May.

According to state officials, data is now showing that efforts to identify and contain the spread of COVID-19 in various congregate care settings has been successful.

With an aggressive multi-pronged strategy, this battle plan is helping ensure Minnesotas long-term care facilities are more resilient and better prepared to contain the spread of COVID-19, Walz said.

Walz said, despite progress, Tuesdays update is not a victory lap.

Weve made progress, but theres still more work to do. Together with our partners in congregate care settings, we must continue to take action to protect our most vulnerable Minnesotans as this pandemic continues, Walz said.

The virus has been particularly deadly to the elderly, many of whom suffer from underlying health issues. As of Tuesday, a majority of the deaths linked to COVID-19 in Minnesota (1,548) have involved a patient at a long-term care (1,189).

In early May, state officials announced the five-point battle plan to protect those living and working in long-term care settings. The plan includes expanded testing for residents, ensuring adequate staffing levels and providing PPE for facilities.

State officials say elements of the battle plan that were successfully implemented include:

Developed testing criteria and a process for facilities to request testing services, making it possible to expand testing for residents and workers in long-term care facilities. Implemented a Nurse Triage Line to provide test results and information on COVID-19 and streamlined the billing process for using the states testing partnership, to provide testing support and troubleshooting to clear barriers faster. Developed a system for prioritizing and disbursing personal protective equipment (PPE) to facilities, including an emergency supply and response system, to ensure these materials are available when needed. Utilized a scheduling software system to connect facilities with staffing needs to available staff, as well as develop triggers and a notification system for when a facility needs additional staffing. In June, 112 shifts were filled through this system, representing 36 percent of available shifts. There are more than 1,100 qualified healthcare professionals signed up in the database. Leveraged partnerships at all levels, including state and federal agencies, as well as long-term care associations and regional healthcare coalitions to improve long-term care testing, staffing, PPE distribution, and patient surge capacity and discharge.

Additionally, as of July 21, data shows half of Minnesotas 368 nursing homes and 77% of the 1,692 assisted living facilities have never had a reported case of COVID-19.

COVID-19 is still part of our lives, and there will continue to be cases, including in long-term care facilities, Minnesota Commissioner of Health Jan Malcolm said. But weve made progress. Were better positioned to limit the spread of COVID-19 and continue to improve every day. Moving forward, we will continue focusing on infection prevention to stop the start of outbreaks and to ensure one case in a facility doesnt end up being a major outbreak.

Malcolm said the downward trend is very encouraging. In early May, MDH reported an average of 23 new facilities daily having an outbreak that number is currently down to an average of six facilities. Also, in the third week of May, MDH reported 137 deaths among long-term care residents in that week, compared to last week where there were 13 deaths among long-term care residents.

Recently, health officials released new guidance on LTC facilities, allowing access for designated family members and other people deemed essential caregivers. Health officials say the guidance balances meeting residents needs and limiting risks of infection.

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Coronavirus (MN): Gov. Walz Announces Progress In Long-Term Care Battle Plan, But Says Theres Still More Work To Do - WCCO | CBS Minnesota

COVID vaccine tracker: 4 ways to find updates on progress – Fast Company

Moderna is making progress. AstraZeneca, too. Johnson & Johnson has scientists tackling the problem on both sides of the Atlantic.

With so many companies racing to build a vaccine that will successfully protect against COVID-19 and free us from global lockdown hell, keeping up with the latest updates can feel impossible. In a way, thats a good thing. Bringing a vaccine to market is no easy taskits filled with a lot of curve balls, dead ends, disappointments, and factors we cant control. For the average news consumer, the best course of action might be to tune out the noise and just follow the big announcements.

But youre not the average news consumer, are you? You need to know everything thats happening in the world of coronavirus vaccine development at every moment.

If you insist on obsessing over vaccine updatestracking every pharmaceutical company, every Phase 1 trial, every candidateIve rounded up a few resources below where you can do just that. Bookmark these lists and try to go on with life!

Follow this link:

COVID vaccine tracker: 4 ways to find updates on progress - Fast Company

Investigative reporter Brendan Kirby talks about major progress on vaccine, help with unemployment – FOX10 News

MOBILE, Ala. (WALA) FOX10 News is committed to getting the facts about how the governments response to the coronavirus affects regular people.

Here is investigative reporter Brendan Kirby with Mondays installment:

QUESTION: Were all hoping for a vaccine. And theres some good news on that front Monday.

BRENDAN: Thats right. Its starting to look like we may get that vaccine sooner rather than later and probably from more than one company.

The latest development comes from Oxford University in London, where researchers reported that they have gotten positive feedback from a Phase I and II clinical trial that began in April. Those results have been published in The Lancet. A thousand healthy adults between the ages of 18 and 55 volunteered, with half getting the vaccine and half getting a placebo.

The vaccine caused a T cell response within 14 days of getting the vaccination. This means white blood cells attacked cells infected with the novel coronavirus. And those subjects had an antibody response within 28 days. This means the antibodies are able to prevent the virus from infecting cells in the body.

That neutralizing activity occurred in the blood of 100 percent of participants. And more good news: There were no serious side effects associated with the vaccine.

Oxford is working with the drug company AstraZeneca for large-scale manufacture and distribution of the vaccine once it gets final approval.

Two other vaccines one by Pfizer and BioNTech, and one by the National Institutes of Health and Moderna have achieved similar results. Moderna is planning to start a Phase III trial later this month with 30,000 volunteers.

QUESTION: Now a question thats been perplexing since the beginning of the pandemic --- why the disease has disproportionately affected African-Americans. And now theres research that might point to a reason why.

BRENDAN: Thats right. Black people in Alabama have been more likely on a per capita basis both to contract the virus and die from it.

So far, 43 percent of lab-confirmed deaths from the novel coronavirus have been black, while African-Americans make up roughly a quarter of the population.

The Centers for Disease Control and Prevention recently published the new research. Researchers from the Medical College of Wisconsin examined 178 COVID-19 cases from March 20 to May 21.

They concluded that people with sickle cell disease who get infected with the novel coronavirus have a high risk for severe outcomes and death.

The statistics show that patients known to have that condition have a 69 percent hospitalization rate, an 11 percent intensive care unit rate and a 7 percent mortality rate. This is particularly alarming given that the average age of this group was younger than 40. Those rates are significantly higher than the rates for all COVID-19 cases in that age range.

African-Americans are far more likely to have sickle cell disease, so this could be at least one explanation for why COVID-19 outcomes have been so much more severe for black Americans.

QUESTION: The unemployment rate continues to drop in Alabama, but there are still lots of people who havent gotten their claims straightened out, and now theyre getting messages telling them their claims are not valid.

BRENDAN: Thats right. The Alabama Department of Labor has tinkered with the process a little bit. But the way it works now is this:

First, you must file for regular unemployment at https://initalilclaims.labor.alabama.gov. If you dont have enough wages during the base period to qualify or you have previously been disqualified, you will be rejected.

But you may still qualify under the Coronavirus, Aid, Relief and Economic Security (CARES) Act program known as Pandemic Unemployment Assistance. You can access that at https://pua.labor.alabama.gov. It is also on the Claim Tracker if you already are in the system. When you apply here, you will be asked a series of questions related to COVID-19.

Based on these questions, the state will determine if you qualify under the expansion passed by Congress to fight the pandemic.

The exact wording of those questions is left to each state. But federal law spells out who is covered and who is not.

QUESTION: And weve gone over that before, but lets remind people of those categories.

BRENDAN: There are 10 categories:

The other five categories are:

(If you have a #COVIDINFO question for investigative reporter Brendan Kirby, email him atBrendan.Kirby@fox10tv.com)

Some encouraging COVID-19 news coming down from the Mobile County Health Department Tuesday.

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Investigative reporter Brendan Kirby talks about major progress on vaccine, help with unemployment - FOX10 News

Buoyed by Red Hat profits, IBM’s CEO sees ‘progress’ in shift to cloud and AI – WRAL Tech Wire

RESEARCH TRIANGLE PARK IBMs stock may be lagging behind its rivals like Microsoft and Amazon, but its new CEOArvind Krishna contends that he is seeing progress in Big Blues push to cloud and artificial intelligence (AI).

On Monday, the tech giant released its second quarterly earnings the second report since Krishna took over the reigns on April 6 and it was a bit of a mixed bag. Clearly not immune to the pandemic sweeping across the globe, IBM reported adjusted earnings to $2.18 per share, a 31 percent drop. Still, it wasbetter than analysts had expected at around $2.07 per share, according to Refinitiv.

Revenue, meanwhile, declined 5 percent to $18.12 billion, versus $17.72 billion as expected.

It comes at a time when IBM headquartered in Armonk, New York with its largest corporate campuses based in RTP has been slower to recover compared to the broader tech space. Since the markets March 23 lows, IBM is only up 30 percent against its industrys 50 percent climb, notedresearch firm Zacks.

IBM earnings drop 31% in Q2 but beat Street expectations

On the flip side: revenue from the Cloud and Cognitive Software business in the second quarter, which includes Cloud and Data platforms like Red Hat, totaled $6.3 billion, up 3 percent.

Total cloud revenue of $23.5 billion over the last 12 months, is up 20 percent (up 23 percent adjusting for divested businesses and currency) exactly one year since IBM bought the open-source software firm for $34 billion. Raleigh-based Red Hats revenue is up 17 percent.

I believe that our strategic vision is taking hold in the marketplace, Krishna saidin a conference call on Monday afternoon, adding that the coronavirus might have accelerated the adoption of IBMs hybrid cloud platform.

Across the board, we are seeing greater demand for Red Hat products, he added. Clients such as Lafayette, American Express, Vodafones Broadridge Financial Solutions, Banco Sabadell and culture bank, all see the value in a hybrid cloud architecture by IBM and Red Hat.

James Kavanaugh, IBM senior vice president and chief financial officer, also reiterated this point.

With Red Hat, we are positioned to win the hybrid cloud architectural battle, he said on the same conference call. We now have over 2400 clients using our container solutions, and nearly 600 IBM services clients, utilizing Red Hat technology.

Still, it hasnt come without some major growing pains and restructuring. As Krishna acknowledged, IBM has been doing a lot of work on the back end to bring its portfolio together in a more cohesive fashion.

That included a massive round of layoffs said to be in the thousands in May. Krishna didnt confirm the figure, but noted that IBM had moved to simplify its team.

He added that IBM isfocused on changing our culture and operating model, so we can make decisions more quickly. Other recent moves involved acquiring Brazils WDG Automation to boost its AI-infused capabilities and US-basedSpanugo for its cloud cybersecurity needs.

Some analysts believe its paying off.

A year into becoming part of IBM, Red Hat has not disappointed and is a major component of the new and diversified life that has been breathed into the IBM portfolio, said saidNicki Catchpole, senior analyst at TBR Cloud and Software.

The continued integration of Red Hats open, flexible and automated solutions coupled with a concerted push to augment and expand upon ML and AI use cases complements IBMs strategic imperative to usher in what has been dubbed Chapter 2 of the Cloud.

AnalystHaris Anwar also remained optimistic.

During the past decade when it came to growth, IBM undeniably disappointed investors, he wrote on Investing.com. But after the Red Hat acquisition, and with new management in place, we see IBM getting back to a growth path once the pandemic is behind us.

IBMs healthy balance sheet, manageable debt and its juicy 5.2 percent dividend yield that pays $6.52 annually, makes the stock attractive for income-oriented investors.

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Buoyed by Red Hat profits, IBM's CEO sees 'progress' in shift to cloud and AI - WRAL Tech Wire

Moleculin Shares Jump on Progress With Virus-Drug Candidate – TheStreet

Moleculin Biotech (MBRX) - Get Reportshares on Tuesday jumped after the drugmaker said a second round of independent lab testing confirmed antiviral activity of its drug candidate, WP1122, as a treatment for coronavirus.

Shares of the Houston company at last check were 31% higher at $1.44.

The lab involved was IIT Research Institute, an affiliate of the Illinois Institute of Technology, which conducted additional in vitro testing ofWP1122, Moleculin said in a statement.

Importantly, the company said, the growth medium, which is designed to support the growth of cells or microorganisms, in this assaywas chosen to reflect the levels of glucose normally found in humans rather than the artificially high levels of glucose often used to speed up in vitro testing.

Based on feedback from the U.S. Food and Drug Administration, Moleculin said itbelieves it may need to demonstrate activity in a covid-19 animal model to successfully submit a request for Investigational New Drug status for WP1122.

"Having validation in yet another virus host cell line provides additional confidence in the antiviral activity we are seeing,"Walter Klemp, chairman and CEO of Moleculin, said in a statement. "Also, using a different independent lab from the last testing that was done provides further validation."

Klemp added that "we are also gaining confidence that in vitro testing results for this class of compounds are significantly affected by the concentration of natural glucose in the microenvironment present during viral replication and continued infection."

"We are also testing other compounds in the portfolio against SARS-CoV-2 and other life-threatening viruses," Klemp said.

"We believe WP1122 is promising, but we also don't want to overlook additional opportunities to potentially provide new and better solutions to other viral diseases."

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Moleculin Shares Jump on Progress With Virus-Drug Candidate - TheStreet