Battlefield: Hardline – THEIR OWN MEDICINE and KNOCK KNOCK Achievement / Trophy Guide (Episode 5) – Video


Battlefield: Hardline - THEIR OWN MEDICINE and KNOCK KNOCK Achievement / Trophy Guide (Episode 5)
Battlefield: Hardline - KNOCK KNOCK and THEIR OWN MEDICINE Achievement / Trophy Guide (Episode 5) Battlefield: Hardline PLAYLIST http://bit.ly/1I2CiYP http://www.randomchievos.com |||||||||...

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Battlefield: Hardline - THEIR OWN MEDICINE and KNOCK KNOCK Achievement / Trophy Guide (Episode 5) - Video

The Medicine Show prst Niven & Gavin from The Greenhouse Dingwall – Concert Window Highlight – Video


The Medicine Show prst Niven Gavin from The Greenhouse Dingwall - Concert Window Highlight
The Medicine Show recorded live on http://www.concertwindow.com on Mar 21st 2015. Learn more about the artist: ...

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American Academy of Pain Medicine Announces 2015 Pain Medicine Award Winners

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Newswise Chicago, IllinoisThe American Academy of Pain Medicine (AAPM) is pleased to announce its Pain Medicine 2015 Awards for exceptional service to the Academy and/or the field of Pain Medicine. Recipients will be honored on Saturday, March 21, 2015 at AAPMs Annual Meeting in National Harbor, MD, where more than 1,000 scientists, physicians and key nonphysician providers convene to discuss and learn the latest in Pain Medicine.

The Pain Medicine 2015 Award winners are:

Lieutenant General Eric Schoomaker, MD, PhDPhilipp M. Lippe, MD, Award Major General Richard W. Thomas, MG, DHAPhilipp M. Lippe, MD, Award This award is given to a physician for outstanding contributions to the social and political aspect of Pain Medicine. Social and political accomplishments could be those that benefit the science, the practice or the recognition of the specialty.

Clifford Wolff, MD, PhDFounders Award This award is given to an individual for outstanding contributions to the science or practice of Pain Medicine. This award is given for continued contributions for the basic or clinical science of Pain Medicine or for demonstration of clinical excellence or innovation in the practice of Pain Medicine.

Perry G. Fine, MDDistinguished Service Award The Distinguished Service Award is given to an individual for commitment and contributions to the American Academy of Pain Medicine. This award is given to an individual for specific outstanding contributions.

Samir K Ballas, MD, FACPPatient Advocacy Award This award recognizes activity of an individual in advocating for appropriate evaluation and treatment of patients suffering from pain. This award was created to honor those healthcare professionals whose deeds reflect their recognition of the importance and impact of the specialty of Pain Medicine.

Michael Cousins, MD, DScPresidential Excellence Award for Education This award honors an individual who has made major contributions to the education of others about Pain Medicine.

ChildKind InternationalRobert G. Addison, MD, Award This award is given for outstanding contributions that foster international collaboration between the American Academy of Pain Medicine and individuals or organizations that support the development of the specialty on an international scope.

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American Academy of Pain Medicine Announces 2015 Pain Medicine Award Winners

American Academy of Pain Medicine Announces 2015 Presidential Commendations

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Newswise Chicago, IllinoisThe American Academy of Pain Medicine (AAPM) is pleased to announce its 2015 Presidential Commendations for exceptional service to the Academy and/or the field of Pain Medicine. Recipients will be honored on Saturday, March 21, 2015 at AAPMs Annual Meeting in National Harbor, MD, where more than 1,000 scientists, physicians and key nonphysician providers convene to discuss and learn the latest in Pain Medicine.

The following outstanding individuals, who have given so much for the Academy, the specialty of pain medicine and patients suffering with pain, have been selected by AAPM President Sean Mackey, MD PhD. Gary Jay Brenner, MD, PhD Bryan C. Hoelzer, MD David Walega, MD. Commended for leadership in building an alliance between AAPM and the Association of Pain Program Directors.

Chester Trip Buckenmaier, MD Patrick Tighe, MD Commended for leading the Academys work in Acute Pain Medicine through the establishment of the Acute Pain Medicine Shared Interest Group and the State of Acute Pain Initiative which is looking at ways to advance research and education in Acute Pain.

Beth Darnall, PhD Perry G. Fine, MD Commended for their work co-chairing the Non-Physician Membership Task Force, which recommended changes to AAPMs Bylaws to welcome more non-physician members, redefining the Clinical Practice Affiliate and Student Membership categories.

Yu Woody Lin, MD, PhD Commended for bringing together the National Institutes of Health and the AAPM membership through a better understanding of the NIH grant programs.

Bill McCarberg, MD Commended for work leading AAPM in Primary Care, particularly with the Primary Care Shared Interest Group and the Primary Care Summit which has brought together eight national healthcare associations to work collaboratively address the need for pain management care and the primary care level.

Christina Spellman Commended for leading the Mayday Fund in its ongoing commitment to improving pain care.

Linda Porter, PhD Commended for leadership of National Pain Strategy efforts.

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American Academy of Pain Medicine Announces 2015 Presidential Commendations

American Academy of Pain Medicine Announces 2015 Pain Medicine Fellowship Excellence Awards

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Newswise Chicago, IllinoisThe American Academy of Pain Medicine (AAPM) is pleased to announce its 2015 Pain Medicine Fellowship Excellence Award Recipients in recognition of a Pain Medicine Fellowship Program that provides an exceptional learning experience to its fellows, preparing them to deliver the highest standard of care to patients with pain. This year the Academy recognizes two programs: Mayo Clinic and Beth Israel Deaconess Medical Center.

Recipient programs will be honored on Saturday, March 21, 2015 at AAPMs Annual Meeting in National Harbor, MD, where more than 1,000 scientists, physicians and key nonphysician providers convene to discuss and learn the latest in Pain Medicine.

Beth Israel Deaconess Medical Center, Brookline, MA The Division of Pain Medicine at Beth Israel Deaconess Medical Center (BIDMC) operates a comprehensive pain management center, a comprehensive headache center and jointly operates the BIDMC Spine Center. The Beth Israel Deaconess Medical Center Pain Medicine Fellowship Program accepts eight fellows each year. The twelve-month fellowship includes intensive training in evaluation and treatment of pain, instruction in the technique of somatic and sympathetic blocks, intra-spinal catheters and pumps, neurolytic blocks, radiofrequency ablation, cryoanalgesia and spinal cord stimulation. Fellows spend time on both the Chronic Pain Service and Acute Pain Service, with ample time allotted for didactic sessions and multidisciplinary meetings at BIDMC and other Harvard teaching hospitals. Successful completion leads to certification eligibility by the American Board of Anesthesiology.

AAPM extends its congratulations to Christine Peeters-Asdourian, MD, Program Director, the Beth Israel Deaconess Medical Center Pain Medicine Fellowship Program and its faculty and staff.

Mayo Clinic, Rochester, MN The Mayo Clinic Pain Medicine Fellowship Program accepts four fellows each year. The Pain Medicine Fellowship focuses on teaching its fellows a multi-disciplinary team approach to managing patients pain. As a result they receive instruction and supervision from physicians board certified in Physical Medicine and Rehabilitation, Anesthesiology, Radiology, Psychology and Neurology. All of these physicians also have completed fellowship training in pain medicine, giving our fellows unique insight into optimal management of patients with various pain conditions. Highlights of the Mayo Clinic Pain Medicine Fellowship include simulation exercises aimed at improving the pain fellows responses to emergency situations and controlled exposure to difficult conversations with standardized patients, cadaver based surgical skills and procedure mastery lab, clinically based research exposure in multiple areas of pain medicine and a comprehensive weekly didactic. In addition, fellows receive exposure to a wide array of acute, chronic, and cancer-associated pain patients.

AAPM extends its congratulations to Bryan C. Hoelzer, MD, Program Director, the Mayo Clinic Pain Medicine Fellowship Program and its faculty and staff.

About AAPM The American Academy of Pain Medicine is the premier medical association for pain physicians and their treatment teams with over 2,500 members. Now in its 32nd year of service, the Academys mission is to optimize the health of patients in pain and eliminate pain as a major public health problem by advancing the practice and specialty of pain medicine through education, training, advocacy, and research. Information is available on the Academys website at http://www.painmed.org .

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American Academy of Pain Medicine Announces 2015 Pain Medicine Fellowship Excellence Awards

American Academy of Pain Medicine Welcomes New Secretary, Tim J. Lamer, MD

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Newswise Chicago, IllinoisThe American Academy of Pain Medicine (AAPM) is pleased to announce Tim J. Lamer, MD as AAPMs Secretary. Dr. Lamer assumes his new position on Saturday, March 21, 2015 at AAPMs Annual Meeting in National Harbor, MD, where more than 1,000 scientists, physicians and key nonphysician providers convene to discuss and learn the latest in Pain Medicine.

Prior to taking office as Secretary, Dr. Lamer served as an AAPM Director-at-Large as well as serving on several AAPM committees/task forces. Dr. Lamer is an Associate Professor of Anesthesiology and a Consultant in the Division of Pain Medicine at the Mayo Clinic in Rochester, Minnesota.

Dr. Lamer holds many appointments and positions in various professional organizations. He is a Founding Editorial Board Member of the journal, Pain Medicine, an Editorial Board Member of the Clinical Journal of Pain and Co-Editor of the Neuromodulation section of the journal Pain Medicine. He also holds membership and various committee positions in the following organizations: International Association for the Study of Pain, North American Neuromodulation Society and the North American Spine Society.

About AAPM The American Academy of Pain Medicine is the premier medical association for pain physicians and their treatment teams with over 2,500 members. Now in its 32nd year of service, the Academys mission is to optimize the health of patients in pain and eliminate pain as a major public health problem by advancing the practice and specialty of pain medicine through education, training, advocacy, and research. Information is available on the Academys website at http://www.painmed.org .

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American Academy of Pain Medicine Welcomes New Secretary, Tim J. Lamer, MD

Penn Medicine: Potential new drug target may protect against certain neurodegenerative diseases

Findings could pave way for precision medicine approach to treatment of neurological diseases

PHILADELPHIA- Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases. Their work, published this month in Neurology, may suggest a neuroprotective target for drug discovery efforts.

"This is the first epigenetic modification of a gene that seems to be protective against neuronal disease," says lead author Corey McMillan, PhD, research assistant professor of Neurology in the Frontotemporal Degeneration Center in the Perelman School of Medicine at the University of Pennsylvania.

Expansions in the offending gene, C9orf72, have been linked with TAR DNA binding protein (TDP-43) which is the pathological source that causes ALS and FTD. "Understanding the role of C9orf72 has the possibility to be truly translational and improve the lives of patients suffering from these devastating diseases," says senior author, Edward Lee, MD, PhD, assistant professor of Neuropathology in Pathology and Laboratory Medicine at Penn.

McMillan and team evaluated 20 patients recruited from both the FTD Center and the ALS Center at the University of Pennsylvania who screened positive for a mutation in the C9orf72 gene and were clinically diagnosed with FTD or ALS. All patients completed a neuroimaging study, a blood test to evaluate C9orf72 methylation levels, and a brief neuropsychological screening assessment. The study also included 25 heathy controls with no history of neurological or psychiatric disease.

MRI revealed reduced grey matter in several regions that were affected in patients compared to controls. Grey matter is needed for the proper function of the brain in regions involved with muscle control, memory, emotions, speech and decision-making. Critically, patients with hypermethylation of C9orf72 showed more dense grey matter in the hippocampus, frontal cortex, and thalamus, regions of the brain important for the above described tasks and affected in ALS and FTD, suggesting that hypermethylation is neuroprotective in these regions.

To validate these findings, the Penn team also looked at autopsies of 35 patients with C9orf72 expansions and found that their pathology also suggested that increased methylation was associated with reduced neuronal loss in both the frontal cortex and hippocampus.

Longitudinal analysis was performed in 11 of the study patients to evaluate the neuroprotective effects of hypermethylation in individuals over their disease course. This showed reduced changes in grey matter of the hippocampus, thalamus, and frontal cortex, associated with hypermethlation suggesting that disease progresses more slowly over time in individuals with C9orf72 hypermethylation. Longitudinal neuropsychological assessments also showed a correlation between protected memory decline and hypermethylation.

These findings are consistent with a growing number of studies which have suggested the neuroprotective effects of the hypermethylation of C9orf72. "We believe that this work provides additional data supporting the notion that C9orf72 methylation is neuroprotective and therefore opens up the exciting possibility of a new avenue for precision medicine treatments and targets for drug development in neurodegenerative disease," says McMillan.

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Penn Medicine: Potential new drug target may protect against certain neurodegenerative diseases

AAFP Celebrates New Recruits to Family Medicine, Acknowledges Work Ahead

It's a family affair for Brian Blank at the University of North Carolina at Chapel Hill, where he celebrates with his wife, Laura, and daughter Lillian after learning that he's going to his number one pick, Duke Family Medicine Residency in Durham, N.C.

Pause for just a moment to cheer this fact: Today, 3,060 graduating medical students choose a career in family medicine.

That's the news just released by the National Resident Matching Program (NRMP) for this annual celebratory event commonly referred to as the Match.

And with that announcement comes the realization that for the sixth straight year, the family medicine match rate ticked upward. Furthermore, 3,216 family medicine residency positions were offered in 2015, an increase of 84 positions compared to 2014.

That overall family medicine fill rate of 95.1 percent -- down slightly from 95.8 percent in 2014 -- represents 60 more positions accepted by graduates compared to last year.

The AAFP Medical Education Division's count of students matching to family medicine includes students who matched into traditional family medicine residency programs as well as into programs that combine family medicine education with other focused training. Those additional programs are

"The Academy congratulates and welcomes these new family medicine recruits," said AAFP President Robert Wergin, M.D., of Milford, Neb., in an interview with AAFP News. "When these residents complete their training programs, there will be plenty of patients across the country eager to welcome new family physicians to their communities."

All the well-wishing must be tempered by this sobering reality: The number of U.S. seniors choosing family medicine slowed at an unexpected rate in 2015, to 1,422 -- with just six more U.S. seniors lining up for the specialty than last year.

Although the Academy will work in coming weeks and months to determine specific factors for that slowing, Wergin pointed to a health care environment in which policymakers and payers have caused instability by shifting positions, reversing decisions and changing the rules -- sometimes simultaneously.

"This uneven environment likely is taking its toll on medical students who are anxious to finish their clinical training and move on with their careers," said Wergin.

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AAFP Celebrates New Recruits to Family Medicine, Acknowledges Work Ahead

Penn Medicine study finds being near greened vacant lots lowers heart rates

PHILADELPHIA - Greening vacant lots may be associated with biologic reductions in stress, according to a new study from the Perelman School of Medicine at the University of Pennsylvania. Residents who walked near newly greened vacant lots had significantly lower heart rates compared to walking near a blighted, or neglected, vacant lot.

"Our goal was to scientifically explore the connection between city environments and stress," said the study's lead author, Eugenia C. South, MD, MHSP, a physician in the department of Emergency Medicine at Penn. "We used heart rate as a physiologic marker of acute stress, and the reduction we found suggests a biological link between urban blight reduction strategies like vacant lot greening and reductions in stress." The study, published online by the American Journal of Public Health, is the first known neighborhood walking trial in which a physiological marker was measured in real-time for residents in their own communities.

The researchers used a heart rate monitor with GPS to measure the stress response in study participants in two randomly selected Philadelphia neighborhoods as they went on a prescribed walk around their neighborhood. Vacant lots in one neighborhood randomly received a greening treatment, while the other neighborhood served as a control and received no treatment. Participants walked past vacant lots before, and then three months after, the greening treatment of randomly selected lots. The greening treatment, performed by the Pennsylvania Horticulture Society, is a low-cost environmental improvement that includes cleaning and removing debris, planting grass and trees, and installing a low wooden post-and-rail fence.

The average heart rate reduction attributable to being in view of the greened lots was over 5 beats per minute (bpm) lower than when near non-greened lots. In contrast, at the control site, there was minimal change in heart rate from the pre- to post-time period when walking past control lots versus non-study vacant lots. In a second analysis, the total net reduction of heart rate when near and in view of greened vacant lots was over 15 bpm. Walks ranged from about 1,500 to 2,000 feet in length.

These data support the conclusion that proximity to greened lots versus trash-strewn lots results in lower heart rates. In response to an acute stressor, the body activates the sympathetic nervous system, resulting in the release of epinephrine, which in turn increases heart rate. Thus, higher heart rates at unexpected moments and because of urban blight, which can be ubiquitous in some city neighborhoods, can be inferred to be evidence of stress. Heart rate change has been used in a few previous studies to evaluate acute stress response, although primarily in indoor laboratory settings.

The current research builds on previously published findings by South and her colleagues, which found that residents living near greened vacant lots feel safer than those near non-greened sites. "Our hypothesis in the earlier published work was that transforming vacant lots from being overrun with weeds and filled with trash to a clean and green space may make it difficult for people to hide weapons and conduct illegal activities such as drug use in or near the space. Thus the lower heart rate response we found in the newly published study may be tied to residents feeling safer and experiencing less stress from their environment."

The study's senior author, Charles C. Branas, PhD, professor of Epidemiology and director of the Urban Health Lab at Penn, observes, "This research on greening urban lots provides an important scientific impetus for urban planners and city officials to take relatively low-cost steps toward improving health for their residents. Future trials that dynamically measure additional biological information, such as cortisol levels (another marker of stress) and blood pressure, are now warranted to further advance our understanding of the relationship between stress and blighted urban environments."

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Other Penn co-authors are Michelle C. Kondo, PhD, and Rose A. Cheney, PhD.

This work was supported by grants from the National Institutes of Health (R01AA020331 and R01AA016187), the Centers for Disease Control and Prevention (U49CE001093), and the Robert Wood Johnson Foundation Health and Society Education Fund, with additional funding from the U.S. Department of Agriculture Forest Service.

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Penn Medicine study finds being near greened vacant lots lowers heart rates

Modernizing Medicine gets investment from IBM

IBM has invested in Modernizing Medicine of Boca Raton, capping a $20 million financing round for the electronic medical records and data company begun by entrepreneur Daniel Cane.

The amount from IBM was not disclosed.

Modernizing Medicine has raised $49 million since its founding in 2010.

The company has been working with IBM Watson for more than a year. The new investment will help Modernizing Medicine expand its market from dermatology to eight medical specialties. It also will further develop schEMA, a mobile app that leverages the cognitive computer power of Watson to give physicians clinical information at the point of patient care, the company said.

The app is designed to analyze massive amounts of published, peer-reviewed medical data and health-care research to help physicians in their practice.

mpounds@sunsentinel.com or 561-243-6650

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Modernizing Medicine gets investment from IBM

Penn Medicine Researchers Pinpoint Potential New Drug Target for Protection against Certain Neurodegenerative Diseases

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Newswise PHILADELPHIA- Penn Medicine researchers have discovered that hypermethylation - the epigenetic ability to turn down or turn off a bad gene implicated in 10 to 30 percent of patients with Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Degeneration (FTD) - serves as a protective barrier inhibiting the development of these diseases. Their work, published this month in Neurology, may suggest a neuroprotective target for drug discovery efforts.

This is the first epigenetic modification of a gene that seems to be protective against neuronal disease, says lead author Corey McMillan, PhD, research assistant professor of Neurology in the Frontotemporal Degeneration Center in the Perelman School of Medicine at the University of Pennsylvania. Expansions in the offending gene, C9orf72, have been linked with TAR DNA binding protein (TDP-43) which is the pathological source that causes ALS and FTD.

Understanding the role of C9orf72 has the possibility to be truly translational and improve the lives of patients suffering from these devastating diseases, says senior author, Edward Lee, MD, PhD, assistant professor of Neuropathology in Pathology and Laboratory Medicine at Penn.

McMillan and team evaluated 20 patients recruited from both the FTD Center and the ALS Center at the University of Pennsylvania who screened positive for a mutation in the C9orf72 gene and were clinically diagnosed with FTD or ALS. All patients completed a neuroimaging study, a blood test to evaluate C9orf72 methylation levels, and a brief neuropsychological screening assessment. The study also included 25 heathy controls with no history of neurological or psychiatric disease.

MRI revealed reduced grey matter in several regions that were affected in patients compared to controls. Grey matter is needed for the proper function of the brain in regions involved with muscle control, memory, emotions, speech and decision-making. Critically, patients with hypermethylation of C9orf72 showed more dense grey matter in the hippocampus, frontal cortex, and thalamus, regions of the brain important for the above described tasks and affected in ALS and FTD, suggesting that hypermethylation is neuroprotective in these regions.

To validate these findings, the Penn team also looked at autopsies of 35 patients with C9orf72 expansions and found that their pathology also suggested that increased methylation was associated with reduced neuronal loss in both the frontal cortex and hippocampus.

Longitudinal analysis was performed in 11 of the study patients to evaluate the neuroprotective effects of hypermethylation in individuals over their disease course. This showed reduced changes in grey matter of the hippocampus, thalamus, and frontal cortex, associated with hypermethlation suggesting that disease progresses more slowly over time in individuals with C9orf72 hypermethylation. Longitudinal neuropsychological assessments also showed a correlation between protected memory decline and hypermethylation.

These findings are consistent with a growing number of studies which have suggested the neuroprotective effects of the hypermethylation of C9orf72. "We believe that this work provides additional data supporting the notion that C9orf72 methylation is neuroprotective and therefore opens up the exciting possibility of a new avenue for precision medicine treatments and targets for drug development in neurodegenerative disease, says McMillan.

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Penn Medicine Researchers Pinpoint Potential New Drug Target for Protection against Certain Neurodegenerative Diseases