Happy 130th Birthday Antisa Khvichava !

From today's AP Article by MISHA DZHINDZHIKHASHVILI:

"Authorities in the former Soviet republic of Georgia claim a woman from a remote mountain village turned 130 on Thursday, making her the oldest person on Earth.

Antisa Khvichava from western Georgia was born on July 8, 1880, said Georgiy Meurnishvili, spokesman for the civil registry at the Justice Ministry."

...

I've always been healthy, and I've worked all my life — at home and at the farm," said Khvichava, in a bright dress and headscarf.

...

Meurnishvili showed two Soviet-era documents that he says attest to her age. Scores of officials, neighbors, friends, and descendants backed up her claim as the world's top senior.

...

Khvichava's 70-year-old son Mikhail apparently was born when his mother was 60. She said she also had two children from a previous marriage, but says they died of hunger during World War II.

While Antisa may never be officially "proven" to be 130 years of age; it certainly proves there are more people alive today living beyond those "on record" and who live well beyond what we consider our norms.

Do Immortals Really Exist? by Ben Abba
http://www.Ben-Abba.com

Messages of Hope from a 2,800 Year Old Man

On this weekend of hope, I thought I would offer everyone some of the messages of inspiration and hope that I received from the remarkable man whom I have been interviewing for many years.

You see, I have also found hope that anything was possible since I first heard the story of the incredible man who defied death 2,000 years ago. But like most of you, I still needed to see, hear, or better yet experience such death defying feats during our modern age to really take "to heart" what we were taught by those famous biblical prophets.

So when it occurred to me that there actually were people living past 125 years of age, and way beyond that number, I started to "feel my heart" stir to the possibility many of our ancient myths may have been much more than stories of hope. Could they conceivably be accounts of actual people who found "the answers to achieving the impossible"? Did these people achieve such incredible feats, because the has nothing to fear? Or because they simply decided not to allow their lives to be conquered by their fears? Or, perhaps, they discovered the secret of living a life without fears which allowed these people to accomplish all that their heart's desired?

Clearly, fear in our lives, disables us, blocks us from growing, stops us for moving forward, hampers us in attaining our life's dreams; and in some cases, perhaps in many ways, destroys our lives from the inside out.

So, if fear is what keeps us from what we want, what we need, what we desire; then is it possible that the "lack of fear" or the "absence of fear" will allow us to obtain what we work for, what we struggle for, and what we sacrifice for?

From what what I have learned from my 2,800 year friend, and from the man who made history 2,000 years ago, is a big, blatant YES to these questions. Certainly they both had fears, but it is quite obvious from what I have heard from the both of them is simply: conquer your fears and you will achieve results.

So how did these 2 incredible men face their fears and conquer them? The simplest of answers I could ascertain from the both of them, happens to be the same message:

1. Do not believe in the fear. Believe instead in the "opposite of fear" which is love.

2. Do not believe in death. Believe instead in the "opposite of death" which is life.

3. Do not live your lives believing in fear and in death, but instead live your lives believing in love and in life.

Have you ever met a person who believes in love and in life? When you do, you automatically be moved by the presence, their words, and all that surrounds them.

Is that not how we, deep down inside, really want to live? A life of contentment without worries, fears, and experiencing life at its fullest?

We can seek out these people for guidance, we can model our lives after these people ...

or we can start today and simply add this simple knowledge into our lives, in everything we say, everything we do, and when we deal with all that life deals to us.

This is what I have learned from a 2,800 year man, who lives this way every day. And I am embarrassed to say, this is what I should have learned from the man who taught us all this; 2,000 years ago today.

Do Immortals Really Exist? by Ben Abba
http://www.Ben-Abba.com

How To Set Up Your Clinical Space Efficiently? A Complete Guide

Were You Aware of the Look of One's Clinic that could help determine the connections that you might have with your patients? A healthy, comfortable clinical space is where the patients can feel relaxed and comfortable. For that you can discover how to favorably impact people who move across the clinic with speedy and very affordable design methods that could smooth workstreams, enhance patient safety, and boost team and patient connections. With more plans and cheap designs for smooth workstreams, you can connect with contractor books. It's easy to understand and is a thorough guidance, which allows you to study successful building, power of positive clinical space, boosting methods, the relation between doctors and patients, and many more. It will guide you on how to tackle the situations and eco-friendly environment for patients.

As a doctor, you operate with individuals to successfully Take Care of present Problems And protect against future disorders. Preventive treatment methods may begin as soon as patients put in the clinic. What can they view and practical experience?  Contractor books are the best source for all the answers you need. ANd tell you exactly how your personnel can navigate the identical distance. How can patients proceed through space all through the trip, and also just how can they believe as though they browse their journey?

Addressing those queries using accessible layout alternatives can reduce Patient stress and enrich team civilization. Even a Free On-line module from the AMA's Actions Ahead Assortment Demonstrates How.

Use those five measures to maximize your clinic's distance:

Develop teamwork stations that enhance interactions

Well-designed Operate channels and components may enhance efficacy and Strengthen team civilization.

 Place test rooms near the workforce's job space to lessen the distance that has to be traveled amongst actions and also enhance assessment place visibility. Because take short guidance from contractor books.

  • Create possibilities on their team to socialize with and nurture an even far more collegial environment. Glass walls make it possible for mates to find each other while preserving solitude and reducing sound.

Place furnishing to encourage patient engagement.

The structure, Designs, and Sorts of desks, evaluation tables along with Chairs may do the job with each other to promote successful interactions and eye.

  • When an individual may sit at a seat to consult together with the medic rather than shelling out the full trip on the exam table, then they indeed are more inclined to experience favorably concerning the trip.
  • Mount machines onto the walls onto a detachable arm or utilize laptops so that your workforce is free to alter their location to confront the individual patient.

Add positive distractions to alleviate patient anxiety.

man in brown shirt sitting on sofa with man leaning on his arm

Patients participate in your practice's environment to collect clues regarding The standard of maintenance they'll obtain. It can impact their faith from the clinic and also their general encounter.

  • Sitting in a living room might be more stressful. Because Patients might feel stressed or frustrated predicated in the waiting-room encounter. Good distractions, such as, for instance, window perspectives of all-natural configurations, divert focus from migraines, and make a constructive disposition.
  • Video may hamper the worries of ready. Because Adding art depicting landscapes using high visual thickness, healthy foliage, and hot weather or even favorable connections involving folks reduces stress.

Reconfigure rooms to feel spacious and welcoming

That Is no requirement to rip walls down, build new chambers to create a Space appear far roomier. Simple rearranging may make a tiny space feel open and more comfortable.

 

  • Jazz a consultation up the distance with added light or enhance stern overhead light. Place test tables in an angle to spare the wall up area for more extended seats.
  • Utilizing lighting, warm-colored paint onto the partitions may increase the constructive result of this art you've picked in the third step.

Connect with patients while incorporating technology

Typing or analyzing an individual's digital Wellness document may shoot Away from individual interaction and frustrate patients and physicians.

  • Raise your attention and share some screen with your patients to favorably impact their participation and adherence to treatment methods. Semi circular desks and big monitors can assist you in maintaining face to face touch. Because we involving patients within their very own info.
  • Try out executing the a-team confirmation approach, at which a nurse, physician assistant, or instruction helps with record-keeping to permit the medic to supply more excellent comprehensive Care to sufferers.

Physicians talk about changing their practice space.

"We had been inconveniencing our sufferers and generating unneeded Work," explained Morris Gagliardi, MD, associate clinical director of Gouverneur overall health at new york.

"Fretting about greater wayfinding for individuals along with groups such as Services together. At the practice demonstrated fantastic chances for individuals to deliver an even better, patient-centered working experience," he explained.

Vermont family doctor Michael Toedt, MD, has discovered Adjoining team chambers having open-distance teams get the job done most useful. He chose never to own some personal offices inside their brand new center.

"Being a doctor, I'm Not operating to Locate the staff members. I have to organize caution," Dr. Toedt explained. "I do not need to worry about this Patient maybe perhaps not after a behavioral wellness pro or dietician. Because we supply the hottest handoff in realtime "

Here’s Why Short Story Dispensers Are The New Normal

The short story is the newest trend globally. The need to read and write those short stories is always there. However, the source for those stories is the question. You can find short stories in the books, magazines, e-books, on websites, in libraries or short story dispensers. Short story dispensers are the latest in the market. There are many books on various things such as home improvement contract, short stories or e-book etc. Thus, these you can benefit from these books as well.

Above all, the short story dispensers are the new normal. People have been using these since its invention. This has made it easier for us to read and enjoy short stories to kill our time and for educational purposes. This literary vending machine prints a blend of original, classic and contemporary works of literature at various locations. This has encouraged people to engage with literary art. Here are some of the reasons why short story dispensers are the new normal.

IT IS EASY TO USE BY ALL AGE GROUPS

Short story dispensers are one of the best ways to read and experience more creativity. These dispensers can be used by all age groups. These are highly accessible by all age groups. Thus, anyone can use these dispensers to enjoy literature anywhere anytime. Students can have easy access to these if their schools and colleges have those dispensers installed in the campus. However, you can search for locations of short story dispensers online as well. You will surely find one near you.

HIGHLY EFFECTIVE AND CUSTOMER-FRIENDLY

man in grey crew-neck t-shirt smiling to woman on counter

One of the best things about these dispensers is that these are highly effective and customer-friendly. You can easily use these even if you are using these for the first time. Therefore, it allows you to work efficiently as well. In addition to this, these dispensers are easy to install. It is customer friendly too. The dispensers are operated automatically. You just have to select the type of story and the duration of the reading. Rest of the work is done by the dispenser itself. Thus, it is very effective to use.

THE DISPENSER BRINGS CULTURE TO UNEXPECTED PLACES

Many underdeveloped or developing countries do not have proper libraries. Thus, it is often very difficult for the students to study and enjoy some quality content. Therefore, dispensers can be used in such areas to promote literature. Dispensers are very light on budget and easy to install. Therefore, these can be easily installed anywhere. This will help in bringing the culture to even unexpected areas. Due to this, the short story dispensers are very common these days.

PAPER AND THE ENVIRONMENT

tree trunk

Nothing could be better than an eco-friendly literature vending machine. The short story dispenser uses thermal printing for printing the stories. You do not need to have any ink or cartridge for printing. Moreover, the paper used in the machine is recycled and is of good quality. Thus, it is highly nature friendly that allows you to enjoy your favourite stories without causing any harm to the environment. The short edition story on a qualitative paper encourages people to keep the story instead of throwing it away.

LOW PRICE LIST

These machines are very light on the pocket. Libraries and colleges can easily install these dispensers. The subscription is for the ones who install it. However, you can use these for free. With the help of 3G internet, you get to choose what type of story you want to hear. Thus, you get to enjoy your favourite stories free of cost. You can also customize messaging at the end of each story. Therefore, this low cost and the highly efficient machine can do wonders to bring back the literature to life.

THE BOTTOM LINE:

Short story dispensers are one of the best things that you need to have in 2020. It is best to be used in colleges, coffee shops, restaurants and other public places. These are simple to use by all age groups. Moreover, it allows to build spark creativity in various platforms to showcase the diversity of the arts in the world. Users are able to print a randomized story from the catalogue of short stories. Thus, it brings back the passion for reading as well. You can find these machines almost in every developed country and city. Moreover, it is highly accessible for the students to read and enjoy some creative content apart from using social media. This is the reason why these literature vending machines are so in these days.

Immortality | philosophy and religion | Britannica

immortality, in philosophy and religion, the indefinite continuation of the mental, spiritual, or physical existence of individual human beings. In many philosophical and religious traditions, immortality is specifically conceived as the continued existence of an immaterial soul or mind beyond the physical death of the body.

The earlier anthropologists, such as Sir Edward Burnett Tylor and Sir James George Frazer, assembled convincing evidence that the belief in a future life was widespread in the regions of primitive culture. Among most peoples the belief has continued through the centuries. But the nature of future existence has been conceived in very different ways. As Tylor showed, in the earliest known times there was little, often no, ethical relation between conduct on earth and the life beyond. Morris Jastrow wrote of the almost complete absence of all ethical considerations in connection with the dead in ancient Babylonia and Assyria.

In some regions and early religious traditions, it came to be declared that warriors who died in battle went to a place of happiness. Later there was a general development of the ethical idea that the afterlife would be one of rewards and punishments for conduct on earth. So in ancient Egypt at death the individual was represented as coming before judges as to that conduct. The Persian followers of Zoroaster accepted the notion of Chinvat peretu, or the Bridge of the Requiter, which was to be crossed after death and which was broad for the righteous and narrow for the wicked, who fell from it into hell. In Indian philosophy and religion, the steps upwardor downwardin the series of future incarnated lives have been (and still are) regarded as consequences of conduct and attitudes in the present life (see karma). The idea of future rewards and punishments was pervasive among Christians in the Middle Ages and is held today by many Christians of all denominations. In contrast, many secular thinkers maintain that the morally good is to be sought for itself and evil shunned on its own account, irrespective of any belief in a future life.

That the belief in immortality has been widespread through history is no proof of its truth. It may be a superstition that arose from dreams or other natural experiences. Thus, the question of its validity has been raised philosophically from the earliest times that people began to engage in intelligent reflection. In the Hindu Katha Upanishad, Naciketas says: This doubt there is about a man departedsome say: He is; some: He does not exist. Of this would I know. The Upanishadsthe basis of most traditional philosophy in Indiaare predominantly a discussion of the nature of humanity and its ultimate destiny.

Immortality was also one of the chief problems of Platos thought. With the contention that reality, as such, is fundamentally spiritual, he tried to prove immortality, maintaining that nothing could destroy the soul. Aristotle conceived of reason as eternal but did not defend personal immortality, as he thought the soul could not exist in a disembodied state. The Epicureans, from a materialistic standpoint, held that there is no consciousness after death, and it is thus not to be feared. The Stoics believed that it is the rational universe as a whole that persists. Individual humans, as the Roman emperor Marcus Aurelius wrote, simply have their allotted periods in the drama of existence. The Roman orator Cicero, however, finally accepted personal immortality. St. Augustine of Hippo, following Neoplatonism, regarded human beings souls as being in essence eternal.

The Islamic philosopher Avicenna declared the soul immortal, but his coreligionist Averros, keeping closer to Aristotle, accepted the eternity only of universal reason. St. Albertus Magnus defended immortality on the ground that the soul, in itself a cause, is an independent reality. John Scotus Erigena contended that personal immortality cannot be proved or disproved by reason. Benedict de Spinoza, taking God as ultimate reality, as a whole maintained his eternity but not the immortality of individual persons within him. The German philosopher Gottfried Wilhelm Leibniz contended that reality is constituted of spiritual monads. Human beings, as finite monads, not capable of origination by composition, are created by God, who could also annihilate them. However, because God has planted in humans a striving for spiritual perfection, there may be faith that he will ensure their continued existence, thus giving them the possibility to achieve it.

The French mathematician and philosopher Blaise Pascal argued that belief in the God of Christianityand accordingly in the immortality of the soulis justified on practical grounds by the fact that one who believes has everything to gain if he is right and nothing to lose if he is wrong, while one who does not believe has everything to lose if he is wrong and nothing to gain if he is right. The German Enlightenment philosopher Immanuel Kant held that immortality cannot be demonstrated by pure reason but must be accepted as an essential condition of morality. Holiness, the perfect accordance of the will with the moral law, demands endless progress only possible on the supposition of an endless duration of the existence and personality of the same rational being (which is called the immortality of the soul). Considerably less-sophisticated arguments both before and after Kant attempted to demonstrate the reality of an immortal soul by asserting that human beings would have no motivation to behave morally unless they believed in an eternal afterlife in which the good are rewarded and the evil are punished. A related argument held that denying an eternal afterlife of reward and punishment would lead to the repugnant conclusion that the universe is unjust.

In the late 19th century, the concept of immortality waned as a philosophical preoccupation, in part because of the secularization of philosophy under the growing influence of science.

Read the original:

Immortality | philosophy and religion | Britannica

Will humans ever be immortal? | Live Science

If you are human, you are going to die. This isn't the most comforting thought, but death is the inevitable price we must pay for being alive. Humans are, however, getting better at pushing back our expiration date, as our medicines and technologies advance.

If the human life span continues to stretch, could we one day become immortal? The answer depends on what you think it means to be an immortal human.

"I don't think when people are even asking about immortality they really mean true immortality, unless they believe in something like a soul," Susan Schneider, a philosopher and founding director of the Center for the Future Mind at Florida Atlantic University, told Live Science. "If someone was, say, to upgrade their brain and body to live a really long time, they would still not be able to live beyond the end of the universe."

Scientists expect the universe will end, which puts an immediate dampener on a mystery about the potential for human immortality. Some scientists have speculated about surviving the death of the universe, as science journalist John Horgan reported for Scientific American, but it's unlikely that any humans alive today will experience the universe's demise anyway.

Related: What happens when you die?

Many humans grow old and die. To live indefinitely, we would need to stop the body from aging. A group of animals may have already solved this problem, so it isn't as far-fetched as it sounds.

Hydra are small, jellyfish-like invertebrates with a remarkable approach to aging. They are largely made up of stem cells that constantly divide to make new cells, as their older cells are discarded. The constant influx of new cells allows hydra to rejuvenate themselves and stay forever young, Live Science previously reported.

"They don't seem to age, so, potentially they are immortal," Daniel Martnez, a biology professor at Pomona College in Claremont, California, who discovered the hydra's lack of aging, told Live Science. Hydra show that animals do not have to grow old, but that doesn't mean humans could replicate their rejuvenating habits. At 0.4 inches (10 millimeters) long, hydra are small and don't have organs. "It's impossible for us because our bodies are super complex," Martnez said.

Humans have stem cells that can repair and even regrow parts of the body, such as in the liver, but the human body is not made almost entirely of these cells, like hydra are. That's because humans need cells to do things other than just divide and make new cells. For example, our red blood cells transport oxygen around the body. "We make cells commit to a function, and in doing that, they have to lose the ability to divide," Martnez said. As the cells age, so do we.

We can't simply discard our old cells like hydra do, because we need them. For example, the neurons in the brain transmit information. "We don't want those to be replaced," Martnez said. "Because otherwise, we won't remember anything." Hydra could inspire research that allows humans to live healthier lives, for example, by finding ways for our cells to function better as they age, according to Martnez. However, his gut feeling is that humans will never achieve such biological immortality.

Though Martnez personally doesn't want to live forever, he thinks humans are already capable of a form of immortality. "I always say, 'I think we are immortal,'" he said. "Poets to me are immortal because they're still with us after so many years and they still influence us. And so I think that people survive through their legacy."

The oldest-living human on record is Jeanne Calment from France, who died at the age of 122 in 1997, according to Guinness World Records. In a 2021 study published in the journal Nature Communications, researchers reported that humans may be able to live up to a maximum of between 120 and 150 years, after which, the researchers anticipate a complete loss of resilience the body's ability to recover from things like illness or injury. To live beyond this limit, humans would need to stop cells from aging and prevent disease.

Related: What's the oldest living thing alive today?

Humans may be able to live beyond their biological limits with future technological advancements involving nanotechnology. This is the manipulation of materials on a nanoscale, less than 100 nanometers (one-billionth of a meter or 400-billionths of an inch). Machines this small could travel in the blood and possibly prevent aging by repairing the damage cells experience over time. Nanotech could also cure certain diseases, including some types of cancer, by removing cancerous cells from the body, according to the University of Melbourne in Australia.

Preventing the human body from aging still isn't enough to achieve immortality; just ask the hydra. Even though hydra don't show signs of aging, the creatures still die. They are eaten by predators, such as fish, and perish if their environment changes too much, such as if their ponds freeze in winter, Martnez said.

Humans don't have many predators to contend with, but we are prone to fatal accidents and vulnerable to extreme environmental events, such as those intensified by climate change. We'll need a sturdier vessel than our current bodies to ensure our survival long into the future. Technology may provide the solution for this, too.

As technology advances, futurists anticipate two defining milestones. The first is the singularity, in which we will design artificial intelligence (A.I.) smart enough to redesign itself, and it will get progressively smarter until it is vastly superior to our own intelligence, Live Science previously reported. The second milestone is virtual immortality, where we will be able to scan our brains and transfer ourselves to a non-biological medium, like a computer.

Researchers have already mapped the neural connections of a roundworm (Caenorhabditis elegans). As part of the so-called OpenWorm project, they then simulated the roundworm's brain in software replicating the neural connections, and programmed that software to direct a Lego robot, according to Smithsonian Magazine. The robot then appeared to start behaving like a roundworm. Scientists aren't close to mapping the connections between the 86 billion neurons of the human brain (roundworms have only 302 neurons), but advances in artificial intelligence may help us get there.

Once the human mind is in a computer and can be uploaded to the internet, we won't have to worry about the human body perishing. Moving the human mind out of the body would be a significant step on the road to immortality but, according to Schneider, there's a catch. "I don't think that will achieve immortality for you, and that's because I think you'd be creating a digital double," she said.

Schneider, who is also the author of "Artificial You: AI and the Future of Your Mind (opens in new tab)" (Princeton University Press, 2019), describes a thought experiment in which the brain either does or doesn't survive the upload process. If the brain does survive, then the digital copy can't be you as you're still alive; conversely, the digital copy also can't be you if your brain doesn't survive the upload process, because it wouldn't be if you did the copy can only be your digital double.

Related: What is consciousness?

According to Schneider, a better route to extreme longevity, while also preserving the person, would be through biological enhancements compatible with the survival of the human brain. Another, more controversial route would be through brain chips.

"There's been a lot of talk about gradually replacing parts of the brain with chips. So, eventually, one becomes like an artificial intelligence," Schneider said. In other words, slowly transitioning into a cyborg and thinking in chips rather than neurons. But if the human brain is intimately connected to you, then replacing it could mean suicide, she added.

The human body appears to have an expiration date, regardless of how it is upgraded or uploaded. Whether humans are still human without their bodies is an open question.

"To me, it's not even really an issue about whether you're technically a human being or not," Schneider said. "The real issue is whether you're the same self of a person. So, what really matters here is, what is it to be a conscious being? And when is it that changes in the brain change which conscious being you are?" In other words, at what point does changing what we can do with our brains change who we are?

Schneider is excited by the potential brain and body enhancements of the future and likes the idea of ridding ourselves of death by old age, despite some of her reservations. "I would love that, absolutely, she said. "And I would love to see science and technology cure ailments, make us smarter. I would love to see people have the option of upgrading their brains with chips. I just want them to understand what's at stake."

Originally published on Live Science.

Excerpt from:

Will humans ever be immortal? | Live Science

Immortality – Wikipedia

Eternal life

Immortality is the concept of eternal life.[2] Some modern species may possess biological immortality.[citation needed]

Some scientists, futurists, and philosophers have theorized about the immortality of the human body, with some suggesting that human immortality may be achievable in the first few decades of the 21st century with the help of certain technologies such as mind uploading (digital immortality).[3] Other advocates believe that life extension is a more achievable goal in the short term, with immortality awaiting further research breakthroughs. The absence of aging would provide humans with biological immortality, but not invulnerability to death by disease or injury. Whether the process of internal immortality is delivered within the upcoming years depends chiefly on research (and in neuron research in the case of internal immortality through an immortalized cell line) in the former view and perhaps is an awaited goal in the latter case.[4]

What form an unending human life would take, or whether an immaterial soul exists and possesses immortality, has been a major point of focus of religion,[citation needed] as well as the subject of speculation and debate. In religious contexts, immortality is often stated to be one of the promises of divinities to human beings who perform virtue or follow divine law.[citation needed]

Life extension technologies promise a path to complete rejuvenation. Cryonics holds out the hope that the dead can be revived in the future, following sufficient medical advancements. While, as shown with creatures such as hydra and Planarian worms, it is indeed possible for a creature to be biologically immortal, it is not known if it will be possible for humans in the near-future.

Immortality in religion refers usually to either the belief in physical immortality or a more spiritual afterlife. In traditions such as ancient Egyptian beliefs, Mesopotamian beliefs and ancient Greek beliefs, the immortal gods consequently were considered to have physical bodies. In Mesopotamian and Greek religion, the gods also made certain men and women physically immortal, whereas in Christianity, many believe that all true believers will be resurrected to physical immortality. Similar beliefs that physical immortality is possible are held by Rastafarians or Rebirthers.

Physical immortality is a state of life that allows a person to avoid death and maintain conscious thought. It can mean the unending existence of a person from a physical source other than organic life, such as a computer.

Pursuit of physical immortality before the advent of modern science included alchemists seeking to create the Philosopher's Stone,[5] and various cultures' legends such as the Fountain of Youth or the Peaches of Immortality inspiring attempts at discovering elixirs of life.

Modern scientific trends, such as cryonics, digital immortality, breakthroughs in rejuvenation, or predictions of an impending technological singularity, to achieve genuine human physical immortality, must still overcome all causes of death to succeed:

There are three main causes of death: aging, disease, and injury[6] Such issues can be resolved with the solutions provided in research to any end providing such alternate theories at present that require unification.

Aubrey de Grey, a leading researcher in the field,[7] defines aging as "a collection of cumulative changes to the molecular and cellular structure of an adult organism, which result in essential metabolic processes, but which also, once they progress far enough, increasingly disrupt metabolism, resulting in pathology and death." The current causes of aging in humans are cell loss (without replacement), DNA damage, oncogenic nuclear mutations and epimutations, cell senescence, mitochondrial mutations, lysosomal aggregates, extracellular aggregates, random extracellular cross-linking, immune system decline, and endocrine changes. Eliminating aging would require finding a solution to each of these causes, a program de Grey calls engineered negligible senescence. There is also a huge body of knowledge indicating that change is characterized by the loss of molecular fidelity.[8]

Disease is theoretically surmountable by technology. In short, it is an abnormal condition affecting the body of an organism, something the body shouldn't typically have to deal with its natural make up.[9] Human understanding of genetics is leading to cures and treatments for a myriad of previously incurable diseases. The mechanisms by which other diseases do damage are becoming better understood. Sophisticated methods of detecting diseases early are being developed. Preventative medicine is becoming better understood. Neurodegenerative diseases like Parkinson's and Alzheimer's may soon be curable with the use of stem cells. Breakthroughs in cell biology and telomere research are leading to treatments for cancer. Vaccines are being researched for AIDS and tuberculosis. Genes associated with type 1 diabetes and certain types of cancer have been discovered, allowing for new therapies to be developed. Artificial devices attached directly to the nervous system may restore sight to the blind. Drugs are being developed to treat a myriad of other diseases and ailments.

Physical trauma would remain as a threat to perpetual physical life, as an otherwise immortal person would still be subject to unforeseen accidents or catastrophes. The speed and quality of paramedic response remains a determining factor in surviving severe trauma.[10] A body that could automatically repair itself from severe trauma, such as speculated uses for nanotechnology, would mitigate this factor. The brain cannot be risked to trauma if a continuous physical life is to be maintained. This aversion to trauma risk to the brain would naturally result in significant behavioral changes that would render physical immortality undesirable for some people.

Organisms otherwise unaffected by these causes of death would still face the problem of obtaining sustenance (whether from currently available agricultural processes or from hypothetical future technological processes) in the face of changing availability of suitable resources as environmental conditions change. After avoiding aging, disease, and trauma, death through resource limitation is still possible, such as hypoxia or starvation.

If there is no limitation on the degree of gradual mitigation of risk then it is possible that the cumulative probability of death over an infinite horizon is less than certainty, even when the risk of fatal trauma in any finite period is greater than zero. Mathematically, this is an aspect of achieving actuarial escape velocity.

Biological immortality is an absence of aging. Specifically it is the absence of a sustained increase in rate of mortality as a function of chronological age. A cell or organism that does not experience aging, or ceases to age at some point, is biologically immortal.[11]

Biologists have chosen the word "immortal" to designate cells that are not limited by the Hayflick limit, where cells no longer divide because of DNA damage or shortened telomeres. The first and still most widely used immortal cell line is HeLa, developed from cells taken from the malignant cervical tumor of Henrietta Lacks without her consent in 1951. Prior to the 1961 work of Leonard Hayflick, there was the erroneous belief fostered by Alexis Carrel that all normal somatic cells are immortal. By preventing cells from reaching senescence one can achieve biological immortality; telomeres, a "cap" at the end of DNA, are thought to be the cause of cell aging. Every time a cell divides the telomere becomes a bit shorter; when it is finally worn down, the cell is unable to split and dies. Telomerase is an enzyme which rebuilds the telomeres in stem cells and cancer cells, allowing them to replicate an infinite number of times.[12] No definitive work has yet demonstrated that telomerase can be used in human somatic cells to prevent healthy tissues from aging. On the other hand, scientists hope to be able to grow organs with the help of stem cells, allowing organ transplants without the risk of rejection, another step in extending human life expectancy. These technologies are the subject of ongoing research, and are not yet realized.[13]

Life defined as biologically immortal is still susceptible to causes of death besides aging, including disease and trauma, as defined above. Notable immortal species include:

As the existence of biologically immortal species demonstrates, there is no thermodynamic necessity for senescence: a defining feature of life is that it takes in free energy from the environment and unloads its entropy as waste. Living systems can even build themselves up from seed, and routinely repair themselves. Aging is therefore presumed to be a byproduct of evolution, but why mortality should be selected for remains a subject of research and debate. Programmed cell death and the telomere "end replication problem" are found even in the earliest and simplest of organisms.[21] This may be a tradeoff between selecting for cancer and selecting for aging.[22]

Modern theories on the evolution of aging include the following:

Individual organisms ordinarily age and die, while the germlines which connect successive generations are potentially immortal. The basis for this difference is a fundamental problem in biology. The Russian biologist and historian Zhores A. Medvedev[25] considered that the accuracy of genome replicative and other synthetic systems alone cannot explain the immortality of germ lines. Rather Medvedev thought that known features of the biochemistry and genetics of sexual reproduction indicate the presence of unique information maintenance and restoration processes at the different stages of gametogenesis. In particular, Medvedev considered that the most important opportunities for information maintenance of germ cells are created by recombination during meiosis and DNA repair; he saw these as processes within the germ cells that were capable of restoring the integrity of DNA and chromosomes from the types of damage that cause irreversible aging in somatic cells.

Some[who?] scientists believe that boosting the amount or proportion of telomerase in the body, a naturally forming enzyme that helps maintain the protective caps at the ends of chromosomes, could prevent cells from dying and so may ultimately lead to extended, healthier lifespans. A team of researchers at the Spanish National Cancer Centre (Madrid) tested the hypothesis on mice. It was found that those mice which were "genetically engineered to produce 10 times the normal levels of telomerase lived 50% longer than normal mice".[26]

In normal circumstances, without the presence of telomerase, if a cell divides repeatedly, at some point all the progeny will reach their Hayflick limit. With the presence of telomerase, each dividing cell can replace the lost bit of DNA, and any single cell can then divide unbounded. While this unbounded growth property has excited many researchers, caution is warranted in exploiting this property, as exactly this same unbounded growth is a crucial step in enabling cancerous growth. If an organism can replicate its body cells faster, then it would theoretically stop aging.

Embryonic stem cells express telomerase, which allows them to divide repeatedly and form the individual. In adults, telomerase is highly expressed in cells that need to divide regularly (e.g., in the immune system), whereas most somatic cells express it only at very low levels in a cell-cycle dependent manner.

Technological immortality is the prospect for much longer life spans made possible by scientific advances in a variety of fields: nanotechnology, emergency room procedures, genetics, biological engineering, regenerative medicine, microbiology, and others. Contemporary life spans in the advanced industrial societies are already markedly longer than those of the past because of better nutrition, availability of health care, standard of living and bio-medical scientific advances.[citation needed] Technological immortality predicts further progress for the same reasons over the near term. An important aspect of current scientific thinking about immortality is that some combination of human cloning, cryonics or nanotechnology will play an essential role in extreme life extension. Robert Freitas, a nanorobotics theorist, suggests tiny medical nanorobots could be created to go through human bloodstreams, find dangerous things like cancer cells and bacteria, and destroy them.[27] Freitas anticipates that gene-therapies and nanotechnology will eventually make the human body effectively self-sustainable and capable of living indefinitely in empty space, short of severe brain trauma. This supports the theory that we will be able to continually create biological or synthetic replacement parts to replace damaged or dying ones. Future advances in nanomedicine could give rise to life extension through the repair of many processes thought to be responsible for aging. K. Eric Drexler, one of the founders of nanotechnology, postulated cell repair devices, including ones operating within cells and using as yet hypothetical biological machines, in his 1986 book Engines of Creation. Raymond Kurzweil, a futurist and transhumanist, stated in his book The Singularity Is Near that he believes that advanced medical nanorobotics could completely remedy the effects of aging by 2030.[28] According to Richard Feynman, it was his former graduate student and collaborator Albert Hibbs who originally suggested to him (circa 1959) the idea of a medical use for Feynman's theoretical micromachines (see biological machine). Hibbs suggested that certain repair machines might one day be reduced in size to the point that it would, in theory, be possible to (as Feynman put it) "swallow the doctor". The idea was incorporated into Feynman's 1959 essay There's Plenty of Room at the Bottom.[29]

Cryonics, the practice of preserving organisms (either intact specimens or only their brains) for possible future revival by storing them at cryogenic temperatures where metabolism and decay are almost completely stopped, can be used to 'pause' for those who believe that life extension technologies will not develop sufficiently within their lifetime. Ideally, cryonics would allow clinically dead people to be brought back in the future after cures to the patients' diseases have been discovered and aging is reversible. Modern cryonics procedures use a process called vitrification which creates a glass-like state rather than freezing as the body is brought to low temperatures. This process reduces the risk of ice crystals damaging the cell-structure, which would be especially detrimental to cell structures in the brain, as their minute adjustment evokes the individual's mind.

One idea that has been advanced involves uploading an individual's habits and memories via direct mind-computer interface. The individual's memory may be loaded to a computer or to a new organic body. Extropian futurists like Moravec and Kurzweil have proposed that, thanks to exponentially growing computing power, it will someday be possible to upload human consciousness onto a computer system, and exist indefinitely in a virtual environment.

This could be accomplished via advanced cybernetics, where computer hardware would initially be installed in the brain to help sort memory or accelerate thought processes. Components would be added gradually until the person's entire brain functions were handled by artificial devices, avoiding sharp transitions that would lead to issues of identity, thus running the risk of the person to be declared dead and thus not be a legitimate owner of his or her property. After this point, the human body could be treated as an optional accessory and the program implementing the person could be transferred to any sufficiently powerful computer.

Another possible mechanism for mind upload is to perform a detailed scan of an individual's original, organic brain and simulate the entire structure in a computer. What level of detail such scans and simulations would need to achieve to emulate awareness, and whether the scanning process would destroy the brain, is still to be determined.[a]

It is suggested that achieving immortality through this mechanism would require specific consideration to be given to the role of consciousness in the functions of the mind. An uploaded mind would only be a copy of the original mind, and not the conscious mind of the living entity associated in such a transfer. Without a simultaneous upload of consciousness, the original living entity remains mortal, thus not achieving true immortality.[31]Research on neural correlates of consciousness is yet inconclusive on this issue. Whatever the route to mind upload, persons in this state could then be considered essentially immortal, short of loss or traumatic destruction of the machines that maintained them.[clarification needed][citation needed]

Transforming a human into a cyborg can include brain implants or extracting a human processing unit and placing it in a robotic life-support system.[citation needed] Even replacing biological organs with robotic ones could increase life span (e.g. pace makers) and depending on the definition, many technological upgrades to the body, like genetic modifications or the addition of nanobots would qualify an individual as a cyborg. Some people believe that such modifications would make one impervious to aging and disease and theoretically immortal unless killed or destroyed.[citation needed]

As late as 1952, the editorial staff of the Syntopicon found in their compilation of the Great Books of the Western World, that "The philosophical issue concerning immortality cannot be separated from issues concerning the existence and nature of man's soul."[32] Thus, the vast majority of speculation on immortality before the 21st century was regarding the nature of the afterlife.

Immortality in ancient Greek religion originally always included an eternal union of body and soul as can be seen in Homer, Hesiod, and various other ancient texts. The soul was considered to have an eternal existence in Hades, but without the body the soul was considered dead. Although almost everybody had nothing to look forward to but an eternal existence as a disembodied dead soul, a number of men and women were considered to have gained physical immortality and been brought to live forever in either Elysium, the Islands of the Blessed, heaven, the ocean or literally right under the ground.Among those humans made immortal were Amphiaraus, Ganymede, Ino, Iphigenia, Menelaus, Peleus, and a great number of those who fought in the Trojan and Theban wars.

Some were considered to have died and been resurrected before they achieved physical immortality. Asclepius was killed by Zeus only to be resurrected and transformed into a major deity. In some versions of the Trojan War myth, Achilles, after being killed, was snatched from his funeral pyre by his divine mother Thetis, resurrected, and brought to an immortal existence in either Leuce, the Elysian plains, or the Islands of the Blessed. Memnon, who was killed by Achilles, seems to have received a similar fate. Alcmene, Castor, Heracles, and Melicertes were also among the figures sometimes considered to have been resurrected to physical immortality. According to Herodotus' Histories, the 7thcenturyBCE sage Aristeas of Proconnesus was first found dead, after which his body disappeared from a locked room. Later he was found not only to have been resurrected but to have gained immortality.

The parallel between these traditional beliefs and the later resurrection of Jesus was not lost on early Christians, as Justin Martyr argued:

The philosophical idea of an immortal soul was a belief first appearing with either Pherecydes or the Orphics, and most importantly advocated by Plato and his followers. This, however, never became the general norm in Hellenistic thought. As may be witnessed even into the Christian era, not least by the complaints of various philosophers over popular beliefs, many or perhaps most traditional Greeks maintained the conviction that certain individuals were resurrected from the dead and made physically immortal and that others could only look forward to an existence as disembodied and dead, though everlasting, souls.

One of the three marks of existence in Buddhism is anatt, "non-self". This teaching states that the body does not have an eternal soul but is composed of five skandhas or aggregates. Additionally, another mark of existence is impermanence, also called anicca, which runs directly counter to concepts of immortality or permanence. According to one Tibetan Buddhist teaching, Dzogchen, individuals can transform the physical body into an immortal body of light called the rainbow body.

Christian theology holds that Adam and Eve lost physical immortality for themselves and all their descendants through the Fall, although this initial "imperishability of the bodily frame of man" was "a preternatural condition".[37]

Christians who profess the Nicene Creed believe that every dead person (whether they believed in Christ or not) will be resurrected from the dead at the Second Coming; this belief is known as universal resurrection. Paul the Apostle, in following his past life as a Pharisee (a Jewish social movement that held to a future physical resurrection[39]), proclaims an amalgamated view of resurrected believers where both the physical and the spiritual are rebuilt in the likeness of post-resurrection Christ, who "will transform our lowly body to be like his glorious body" (ESV).[40] This thought mirrors Paul's depiction of believers having been "buried therefore with him [that is, Christ] by baptism into death" (ESV).[41]

N.T. Wright, a theologian and former Bishop of Durham, has said many people forget the physical aspect of what Jesus promised. He told Time: "Jesus' resurrection marks the beginning of a restoration that he will complete upon his return. Part of this will be the resurrection of all the dead, who will 'awake', be embodied and participate in the renewal. Wright says John Polkinghorne, a physicist and a priest, has put it this way: 'God will download our software onto his hardware until the time he gives us new hardware to run the software again for ourselves.' That gets to two things nicely: that the period after death (the Intermediate state) is a period when we are in God's presence but not active in our own bodies, and also that the more important transformation will be when we are again embodied and administering Christ's kingdom."[42] This kingdom will consist of Heaven and Earth "joined together in a new creation", he said.

Christian apocrypha include immortal human figures such as Cartaphilus[43] and Longinus[44] who were cursed with physical immortality for various transgressions against Christ during the Passion. Leaders of sects such as John Asgill and John Wroe taught followers that physical immortality was possible.[45][46]

Hindus believe in an immortal soul which is reincarnated after death. According to Hinduism, people repeat a process of life, death, and rebirth in a cycle called samsara. If they live their life well, their karma improves and their station in the next life will be higher, and conversely lower if they live their life poorly. After many life times of perfecting its karma, the soul is freed from the cycle and lives in perpetual bliss. There is no place of eternal torment in Hinduism, although if a soul consistently lives very evil lives, it could work its way down to the very bottom of the cycle.[citation needed]

There are explicit renderings in the Upanishads alluding to a physically immortal state brought about by purification, and sublimation of the 5 elements that make up the body. For example, in the Shvetashvatara Upanishad (Chapter 2, Verse 12), it is stated "When earth, water, fire, air and sky arise, that is to say, when the five attributes of the elements, mentioned in the books on yoga, become manifest then the yogi's body becomes purified by the fire of yoga and he is free from illness, old age and death."

Another view of immortality is traced to the Vedic tradition by the interpretation of Maharishi Mahesh Yogi:

That man indeed whom these (contacts)do not disturb, who is even-minded inpleasure and pain, steadfast, he is fitfor immortality, O best of men.[47]

To Maharishi Mahesh Yogi, the verse means, "Once a man has become established in the understanding of the permanent reality of life, his mind rises above the influence of pleasure and pain. Such an unshakable man passes beyond the influence of death and in the permanent phase of life: he attains eternal life... A man established in the understanding of the unlimited abundance of absolute existence is naturally free from existence of the relative order. This is what gives him the status of immortal life."[47]

An Indian Tamil saint known as Vallalar claimed to have achieved immortality before disappearing forever from a locked room in 1874.[48][unreliable source?][49]

The traditional concept of an immaterial and immortal soul distinct from the body was not found in Judaism before the Babylonian exile, but developed as a result of interaction with Persian and Hellenistic philosophies. Accordingly, the Hebrew word nephesh, although translated as "soul" in some older English-language Bibles, actually has a meaning closer to "living being".[50][need quotation to verify] Nephesh was rendered in the Septuagint as (psch), the Greek word for soul.[citation needed]

The only Hebrew word traditionally translated "soul" (nephesh) in English language Bibles refers to a living, breathing conscious body, rather than to an immortal soul.[b]In the New Testament, the Greek word traditionally translated "soul" () has substantially the same meaning as the Hebrew, without reference to an immortal soul.[c]"Soul" may refer either to the whole person, the self, as in "three thousand souls" were converted in Acts 2:41 (see Acts 3:23).

The Hebrew Bible speaks about Sheol (), originally a synonym of the grave the repository of the dead or the cessation of existence, until the resurrection of the dead. This doctrine of resurrection is mentioned explicitly only in Daniel 12:14 although it may be implied in several other texts. New theories arose concerning Sheol during the intertestamental period.

The views about immortality in Judaism is perhaps best exemplified by the various references to this in Second Temple period. The concept of resurrection of the physical body is found in 2 Maccabees, according to which it will happen through recreation of the flesh.[52] Resurrection of the dead is specified in detail in the extra-canonical books of Enoch,[53] and in Apocalypse of Baruch.[54] According to the British scholar in ancient Judaism P.R. Davies, there is "little or no clear reference ... either to immortality or to resurrection from the dead" in the Dead Sea scrolls texts.[55]Both Josephus and the New Testament record that the Sadducees did not believe in an afterlife,[56]but the sources vary on the beliefs of the Pharisees. The New Testament claims that the Pharisees believed in the resurrection, but does not specify whether this included the flesh or not.[57] According to Josephus, who himself was a Pharisee, the Pharisees held that only the soul was immortal and the souls of good people will be reincarnated and "pass into other bodies," while "the souls of the wicked will suffer eternal punishment."[58]The Book of Jubilees seems to refer to the resurrection of the soul only, or to a more general idea of an immortal soul.[59]

Rabbinic Judaism claims that the righteous dead will be resurrected in the Messianic Age, with the coming of the messiah. They will then be granted immortality in a perfect world. The wicked dead, on the other hand, will not be resurrected at all. This is not the only Jewish belief about the afterlife. The Tanakh is not specific about the afterlife, so there are wide differences in views and explanations among believers.[citation needed]

It is repeatedly stated in the Lshi Chunqiu that death is unavoidable.[60] Henri Maspero noted that many scholarly works frame Taoism as a school of thought focused on the quest for immortality.[61] Isabelle Robinet asserts that Taoism is better understood as a way of life than as a religion, and that its adherents do not approach or view Taoism the way non-Taoist historians have done.[62] In the Tractate of Actions and their Retributions, a traditional teaching, spiritual immortality can be rewarded to people who do a certain amount of good deeds and live a simple, pure life. A list of good deeds and sins are tallied to determine whether or not a mortal is worthy. Spiritual immortality in this definition allows the soul to leave the earthly realms of afterlife and go to pure realms in the Taoist cosmology.[63]

Zoroastrians believe that on the fourth day after death, the human soul leaves the body and the body remains as an empty shell. Souls would go to either heaven or hell; these concepts of the afterlife in Zoroastrianism may have influenced Abrahamic religions. The Persian word for "immortal" is associated with the month "Amurdad", meaning "deathless" in Persian, in the Iranian calendar (near the end of July). The month of Amurdad or Ameretat is celebrated in Persian culture as ancient Persians believed the "Angel of Immortality" won over the "Angel of Death" in this month.[64]

Alcmaeon of Croton argued that the soul is continuously and ceaselessly in motion. The exact form of his argument is unclear, but it appears to have influenced Plato, Aristotle, and other later writers.[65]

Plato's Phaedo advances four arguments for the soul's immortality:[66]

Plotinus offers a version of the argument that Kant calls "The Achilles of Rationalist Psychology". Plotinus first argues that the soul is simple, then notes that a simple being cannot decompose. Many subsequent philosophers have argued both that the soul is simple and that it must be immortal. The tradition arguably culminates with Moses Mendelssohn's Phaedon.[67]

Theodore Metochites argues that part of the soul's nature is to move itself, but that a given movement will cease only if what causes the movement is separated from the thing moved an impossibility if they are one and the same.[68]

Avicenna argued for the distinctness of the soul and the body, and the incorruptibility of the former.[d]

The full argument for the immortality of the soul and Thomas Aquinas' elaboration of Aristotelian theory is found in Question 75 of the First Part of the Summa Theologica.[74]

Ren Descartes endorses the claim that the soul is simple, and also that this entails that it cannot decompose. Descartes does not address the possibility that the soul might suddenly disappear.[75]

In early work, Gottfried Wilhelm Leibniz endorses a version of the argument from the simplicity of the soul to its immortality, but like his predecessors, he does not address the possibility that the soul might suddenly disappear. In his monadology he advances a sophisticated novel argument for the immortality of monads.[76]

Moses Mendelssohn's Phaedon is a defense of the simplicity and immortality of the soul. It is a series of three dialogues, revisiting the Platonic dialogue Phaedo, in which Socrates argues for the immortality of the soul, in preparation for his own death. Many philosophers, including Plotinus, Descartes, and Leibniz, argue that the soul is simple, and that because simples cannot decompose they must be immortal. In the Phaedon, Mendelssohn addresses gaps in earlier versions of this argument (an argument that Kant calls the Achilles of Rationalist Psychology). The Phaedon contains an original argument for the simplicity of the soul, and also an original argument that simples cannot suddenly disappear. It contains further original arguments that the soul must retain its rational capacities as long as it exists.[77]

The possibility of clinical immortality raises a host of medical, philosophical, and religious issues and ethical questions. These include persistent vegetative states, the nature of personality over time, technology to mimic or copy the mind or its processes, social and economic disparities created by longevity, and survival of the heat death of the universe.

Physical immortality has also been imagined as a form of eternal torment, as in the myth of Tithonus, or in Mary Shelley's short story The Mortal Immortal, where the protagonist lives to witness everyone he cares about die around him. For additional examples in fiction, see Immortality in fiction.

Kagan (2012)[78] argues that any form of human immortality would be undesirable. Kagan's argument takes the form of a dilemma. Either our characters remain essentially the same in an immortal afterlife, or they do not:

Either way, Kagan argues, immortality is unattractive. The best outcome, Kagan argues, would be for humans to live as long as they desired and then to accept death gratefully as rescuing us from the unbearable tedium of immortality.[78]

If human beings were to achieve immortality, there would most likely be a change in the world's social structures. Sociologists argue that human beings' awareness of their own mortality shapes their behavior.[80] With the advancements in medical technology in extending human life, there may need to be serious considerations made about future social structures. The world is already experiencing a global demographic shift of increasingly ageing populations with lower replacement rates.[81] The social changes that are made to accommodate this new population shift may be able to offer insight on the possibility of an immortal society.

Sociology has a growing body of literature on the sociology of immortality, which details the different attempts at reaching immortality (whether actual or symbolic) and their prominence in the 21st century. These attempts include renewed attention to the dead in the West,[82] practices of online memorialization,[83] and biomedical attempts to increase longevity.[84] These attempts at reaching immortality and their effects in societal structures have led some to argue that we are becoming a "Postmortal Society".[85][86] Foreseen changes to societies derived from the pursuit of immortality would encompass societal paradigms and worldviews, as well as the institutional landscape. Similarly, different forms of reaching immortality might entail a significant reconfiguration of societies, from becoming more technologically-oriented to becoming more aligned with nature [87]

Immortality would increase population growth,[88] bringing with it many consequences as for example the impact of population growth on the environment and planetary boundaries.

Although some scientists state that radical life extension, delaying and stopping aging are achievable,[89] there are no international or national programs focused on stopping aging or on radical life extension. In 2012 in Russia, and then in the United States, Israel and the Netherlands, pro-immortality political parties were launched. They aimed to provide political support to anti-aging and radical life extension research and technologies and at the same time transition to the next step, radical life extension, life without aging, and finally, immortality and aim to make possible access to such technologies to most currently living people.[90]

There are numerous symbols representing immortality. The ankh is an Egyptian symbol of life that holds connotations of immortality when depicted in the hands of the gods and pharaohs, who were seen as having control over the journey of life. The Mbius strip in the shape of a trefoil knot is another symbol of immortality. Most symbolic representations of infinity or the life cycle are often used to represent immortality depending on the context they are placed in. Other examples include the Ouroboros, the Chinese fungus of longevity, the ten kanji, the phoenix, the peacock in Christianity,[91] and the colors amaranth (in Western culture) and peach (in Chinese culture).

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Immortality - Wikipedia

Immortality (video game) – Wikipedia

2022 video game

Immortality is an interactive film video game developed by Sam Barlow and published by Half Mermaid Productions. It was released for Windows and Xbox Series X/S in August 2022. Android and iOS versions through Netflix app were released in November 2022. A macOS version is also in the works.

The game is based on the fictional model turned actress Marissa Marcel (Manon Gage) who had starred in three movies from 1968, 1970, and 1999 but which were never released. Marcel has since gone missing, creating a mystery for the player to solve. In the same manner as Barlow's prior works Her Story and Telling Lies, Immortality incorporates the use of full-motion video for the player to piece together Marcel's fate.[1] The player begins with one clip from one of the three films, and the player can pause and click on a person or item of interest. The game will then show all other clips from the three films, as well as behind-the-scenes production footage and television and interview clips, which the player can review and seek out further persons or items.[2]

Much of the plot is shown through secret footage the player reveals by manipulating the footage from the films, TV interviews, etc.; because of this, the plot progresses in a non-chronological, broken narrative format. This synopsis follows chronological order.

Two immortal beings, credited as "The One" and "The Other One," predate humanity and are able to live indefinitely by taking on the forms of humans and living their lives. This ostensibly ends the human's life, though elements of their personalities and memories mingle with the beings' own personalities and memories. Their kind's numbers have dwindled since human civilization began. They can regenerate from being killed, though some methods, especially burning, are implied to be permanent, although the ending throws even this into question.

The One and The Other One seem to be a pair, though their relationship is never explicitly defined. The One is fascinated with humanity, particularly their proclivities for sex, violence, and art. The Other One is ambivalent toward Humanity, seeing them as inferior copies of the immortal beings, and believes that the immortals and humans should exist separate from each other. However, they indulge The One in their exploration of humanity.

The One becomes Marissa Marcel, a French girl who is implied to have been mortally wounded by German soldiers in World War II and absorbed by The One as a mercy. In 1968 she auditions and is awarded a role in Ambrosio, a film based on the gothic novel The Monk by Matthew Lewis. During filming she becomes romantically involved with director of photography John Durick. The film's director, Arthur Fischer, steals the negatives, which prevents the film from ever being released.

Two years later, John directs Minsky, a detective story set in New York City's avant-garde art world. He casts Marissa as a lead; she also has significant creative input in the rest of the film. The Other One, taking the form of a man named Carl Goodman, also joins the cast as the film's other lead. Marissa and John's relationship deteriorates, possibly because Carl also begins a romantic relationship with John. While filming a scene, Marissa shoots and kills Carl with a prop gun at point blank range. To the rest of the cast and crew, this appears to be a tragic accident; the truth is that The One intentionally killed The Other One. Carl's death causes filming to halt, and the film is never released. Marissa reveals to John her and Carl's true natures as immortals, and tells him that she killed Carl. John is horrified by this, which disappoints The One. She murders John and takes on his form, shedding Marissa's form. The general public assumes Marissa became a recluse.

Nearly 30 years later, Fischer gives the negatives from Ambrosio to John in an attempt to free himself from deathbed regrets. The nostalgia causes The One to remember Marissa fondly and take on her form simultaneously with John's form, essentially existing in two bodies at once. Meanwhile, the actress Amy Archer watches footage of Carl's death, which allows The Other One to take her form. John, Marissa, and Amy begin work on a new film, Two of Everything, a drama film about a pop star named Maria who allows her coincidentally-identical body double Heather to pretend to be Maria so that she can live a pop star lifestyle and Maria can have a break from it. John directs, Marissa plays both Maria and Heather (paralleling The One's attempt to exist as two people), and Amy plays a villain character who murders Heather, thinking she is Maria. During filming, both John and Marissa behave strangely: Marissa is sometimes unresponsive and suffers nosebleeds, and both she and John occasionally collapse in exhaustion. John is also frequently absent during filming, implying that he vanishes when The One cannot maintain both forms. In several pieces of footage Amy pleads with Marissa to take breaks, but Marissa rebuffs her concerns. During one take, Marissa spontaneously bleeds from her head. The Other One tells her that their kind cannot sustain existing in two forms at once. Before Marissa becomes completely unresponsive, she asks Amy/The Other One to help her die onscreen as The Other One did, and therefore become truly immortalized in film. Amy films herself burning an inert Marissa's body. Two of Everything never finishes filming.

After the player watches Marissa burn, the grid containing all the clips they've collected during the game slowly disappear, revealing the face of The One. They tell the player they are "part of you, now," implying the player is their new host.

Barlow had announced Immortality as "Project Ambrosio" in 2020 and had blogged about its development over the year. His writing suggested that the game may have more of a horror-themed nature than his previous games, along with several passages marked as if classified or redacted information.[3][4] Barlow brought on three additional screenwriters for the game: Allan Scott, Amelia Gray, and Barry Gifford.[1] The game was formally announced during the E3 2021 event in June that year for Microsoft Windows, iOS, and Android.[1] In March 2022, Half Mermaid Productions announced that a version for Xbox Series X/S would also be available at launch.[5] During PC Gaming Show 2022, it was announced that the game would release on 26 July 2022, but was later delayed to 30 August 2022.[6][7] In August 2022, it was announced that the mobile ports would be published by Netflix.[8]

Immortality premiered at the Tribeca Film Festival in June 2022.[9] It was subsequently released on August 30, 2022 on Xbox Series X/S, Xbox Game Pass, and Windows via Steam and GOG.[10] It released on Netflix via Google Play and IOS in November 2022.[11]

Immortality received "generally favorable" reviews according to review aggregator Metacritic.[12][13]

In an early review due to its print format, Edge awarded Immortality a perfect 10/10 score, the 24th game in its history to do so.[25]

In addition, Immortality has been praised for its acting performances, notably that of Manon Gage, who has received critical acclaim for her performance as Marissa Marcel. Edge called her performance "outstanding." Vulture's Lewis Gordon called it "a knockout performance."[26] PJ O'Reilly of Pure Xbox said Gage "provides a core performance that marks her out as an absolute superstar in the making."[27] Vice's Cameron Kunzelman noted: "...watching Gage play Marcel playing these characters is like watching someone juggle while riding a unicycle in the middle of the Indy 500, and she does it perfectly and without breaking a sweat. Its really something."[28]

Charlotta Mohlin has also been praised for her performance, with Edge calling her "remarkable",[25] and Tristan Ogilvie of IGN calling her "spellbinding."[29] Well Played AU's James Wood said "[Mohlin's] work is something I will be thinking about for years to come."[30] Nate Hermanson of Video Games Are Good noted Mohlin "[makes] us cry, laugh, shudder, and blush in almost every scene she [is] in."[31]

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Immortality (video game) - Wikipedia

CSI: Immortality (TV Movie 2015) – IMDb

There is a thing called CSI Effect. People *expect* ultra fast DNA tests, they expect "scientific evidence" very far from reality. This final chapter brings conclusion to the show. But the new case lacks original ideas, it is just as tired as the worst seasons of the show, and and it manages to inherit all the issues the CSI series had.

Old stars and characters return to a "yet another" important and big scene that can showcase it all, but as the show tries to amaze us with "detective fantasy" it manages to serve us more nonsense and an uninteresting plot.

When we watched the show the tale about individual characters added a bit of spice to this bland soup of scientific nonsense. The characters and how they performed added a lot to the "drama" in this series. But as a "service to old fans" they wanted to add conclusion to the show, and brought back (revived) old characters in an attempt to please most of us. Too bad it meant: We lost continuity.

And events in the team and continuity were one of the key redeeming qualities of the original show.

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CSI: Immortality (TV Movie 2015) - IMDb

Immortality for PC Reviews – Metacritic

WARNING: THIS IS NOT A VIDEOGAME NOR A INTERACTIVE COMMERCIAL MOVIE.Can't even say if this is a movie. Well maybe technically? I don't know.WARNING: THIS IS NOT A VIDEOGAME NOR A INTERACTIVE COMMERCIAL MOVIE.Can't even say if this is a movie. Well maybe technically? I don't know. Once defined this , I could say if you expect something related to obamaflix blackhomo crap streaming something its not the case either.This is more a concept ,artcinema, performance, theater, related. Is like a bunch of very short films just related to the main actress somehow that varies from boring to odd to eerie ,with a lot of symbolism. The interaction with this short firms is quite odd too and lead to anothers and cannot be accessed in a main menu or something. But this is a part of the whole experience.This is not for everybody besides art lovers , actor and director students and related.I cannot rate this production as Im not an expert in the area so I just throw a 7 just giving the benefit of their work. Expand

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Immortality for PC Reviews - Metacritic

Marbled Soles Appears On The Nike Giannis Immortality 2 – Sneaker News

Giannis Antetokounmpo and the Milwaukee Bucks are facing their biggest challenge yet this postseason as theyve dropped Game 4 on their home floor to have the Conference semi-final series against the Celtics completely tied up. Theyll have to win one more in Boston (or potentially two) to advance, and it all hinges on the performance of the one called the Greek Freak.

While the Giannis Immortality 2 signature shoe isnt out on the market yet, were seeing more new colorways that are planned to drop throughout the summer. This achieves a standard black/white colorway, but with university blue accents and golden trim adding some character to the shoes. The marbled soles, mimicking the chiseled statues of Greek mythology, add even more personality to the straightforward colorway.

Full family sizes of this Giannis Immortality 2 are expected; see the official images ahead and well let you know when these are available.

Where to Buy

Make sure to follow @kicksfinder for live tweets during the release date.

Mens: N/AStyle Code: N/A

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Marbled Soles Appears On The Nike Giannis Immortality 2 - Sneaker News

Old Mice ‘Rejuvenated’ With Injections of Brain Fluid From The Young – ScienceAlert

While immortality might forever be out of reach, a long, healthy retirement is the stuff dreams are made of.

To that end, a recent study suggests that the kinds of memory problems common in old age can be reversed, and all it takes is some cerebrospinalfluid harvested from the young. In mice, at least.

If this is sounding a little familiar, you might be thinking of a similar series of studies done back in the mid-2010s, which found that older mice could be generally 'rejuvenated' with the blood of younger animals both from humans and from mice. The FDA even had to warn people to stop doing it.

This new study instead examined the links between memory and cerebrospinalfluidfluid (CSF), and the results show considerable promise, even providing a mechanism for how it works, and highlighting a potential growth factor that could mimic the results.

"We know that CSF composition changes with age, and, in fact, these changes are used routinely in the clinic to assess brain health and disease biomarkers," Stanford University neurologist Tal Iram told ScienceAlert.

"However, we don't know well how these changes affect the function of the cells in the aging brain."

To investigate, the researchers, led by Iram, took older mice (between 1822 months old) and gave them light shocks on the foot, at the same time as a tone and flashing light were activated. The mice were then split into groups, and either given young mouse CSF (from animals 10 weeks old) or artificial CSF.

In experiments like this, if the mice 'freeze' when they see the tone and light, it means they're remembering the foot shock, and are preparing for it to happen again.

In this study, three weeks after the foot shocks were conducted (which the team called "memory acquisition"), the researchers tested the mice, finding that the animals that had been given the CSF from young miceshowed higher-than-average freezing rates, suggesting they had better memory.

This was followed up by a battery of other experiments to test the theory, which revealed that certain genes (that are different in young-versus-old CSF) could be used to get the same response. In other words, without needing to extract someone's brain fluid.

"When we took a deeper look into gene changes that occurred in the hippocampus (a region associated with memory and aging-related cognitive decline), we found, to our surprise, a strong signature of genes that belong to oligodendrocytes," Iram told ScienceAlert.

"Oligodendrocytes are unique because their progenitors are still present in vast numbers in the aged brain, but they are very slow in responding to cues that promote their differentiation. We found that when they are re-exposed to young CSF, they proliferate and produce more myelin in the hippocampus."

In the mice, an infusion of a fibroblast growth factor called FGF17 was able to boost oligodendrocyte progenitor cells in a similar way to the CSF injection.

Oligodendrocytes are particularly helpful because they produce myelin, a material that covers and insulates neuron fibers. The infusion of FGF17 was itself able to help the older mice increase memory ability.

A diagram showing the results in the cell. (Nature)

While this field of research has a very very long way to go before we can use such insights to increase memory in older humans, the findings are exciting, and hopefully future studies following these leads can help us live out our retirement without having to resort to the body fluids of young whippersnappers.

"Iram and colleagues have broken ground in the field of brain health and aging by discovering that young CSF contains a factor that aids memory recall in older mice," write researchers Miriam Zawadzki & Maria K. Lehtinen from Boston Children's Hospital in an accompanying News and Views piece.

"Not only does the study imply that FGF17 has potential as a therapeutic target, but it also suggests that routes of drug administration that allow therapeutics to directly access the CSF could be beneficial in treating dementia. Any such treatments will be hugely helpful in supporting our aging population."

The research has been published in Nature.

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Old Mice 'Rejuvenated' With Injections of Brain Fluid From The Young - ScienceAlert

Eddie Kingston Wants To Win An NJPW G1 Climax Tournament And Earn His Squared Circle Immortality – Fightful

Eddie Kingston wants to live forever by participating in the G1 Climax Tournament.

Eddie Kingston bears his soul in everything he does in professional wrestling. It is part of what connects professional wrestling fans to his journey on such a deep level. A huge part of that journey and Eddie Kingstons love of professional wrestling is his fondness for Japanese wrestling. Kingston has openly admitted that he takes a lot of his move set from top Japanese stars such as Mitsuharu Misawa, Toshiaki Kawada, Kenta Kobashi, and others.

Another Name Advances To Semi-Finals Of Owen Hart Foundation Men's Tournament On 5/11 AEW Dynamite

In a new interview with Sean Ross Sapp, Kingston further explains his love of Japanese wrestling and how he feels about the working relationship between AEW and New Japan Pro-Wrestling ahead of the Forbidden Door pay-per-view on June 26 and his upcoming match against Tomohiro Ishii at NJPW STRONG Capital Collision.

I dont think people fully understand. Yes, my favorite wrestling was All Japan during the 90s. But I watched New Japan as well, Kingston explained. Cause I remember the Three Musketeers. I remember Keiji Muto, aka the Great Muta, who was the first Japanese wrestler I ever saw. Then, of course, theres Masahiro Chono. I thought the STF was the deadliest move in the world. I remember Jim Ross screaming about it on commentary and Chono learned it from Lou Thesz. Thats a name you know, even if you have never seen him wrestle. But you know the name. Then you had Shinya Hashimoto, who was just a badass. He was my personal favorite.

I know the history and it means a lot, Kingston continued. Thats why I mentioned Tenryu and Riki Choshu to Ishii, to let him know, I know who trained you, dog. I watched them. I studied them as well. So I know who they are. I know the history. Thats why wipe my feet, of course, and I give a kiss to the logo in the middle of the ringtake my hand, put a little kiss on it. out of respect. It feels great. All that political stuff, I didnt see it. As soon as I was able to work with AEW, and I was lucky enough and blessed enough to do it, STRONG hit me up a couple of weeks later and AEW, even before this working relationship, was like, Yeah, okay. Do it. So I never saw all the political side. But for those that did, sorry. Now you dont have to see it.

Speaking more directly about the Forbidden Door event and concept, Kingston size that in his two decades in wrestling, he has never seen promotions come together the way so many have in recent years.

Its amazing. Its an amazing feeling. In my twenty-year career, I have never seen it like this where everybodys working together, he said. "Theres no political B.S. where, I dont like this person because of whatever. Its, Oh, you want to do the show? Fine, go make your money or Thats a really good match-up. Maybe we can show it here. Everybodys starting to work together, which is what I thought wrestling was. Remember, Im an 80s baby. So I grew up at the tail end of the territories. So I saw, at one point in time, all the territories trying to work together to beat Vince. So I thought thats the way it was supposed to be. Not to beat Vince, but to work together and have more places to work. I think its great. Ive never seen it like this.

Kingston did not want to overthink about his potential position on that card on June 26 because he isn't sure if you will even be booked yet. However, he does name a dream opponent from Japan that he would like to face, Jun Akiyama, who although he was never one of the four pillars of AJPW in the 90s, was always across the ring from Mitsuharu Misawa, Kenta Kobashi, Akira Taue, and Toshiaki Kawada, and eventually made a major name for himself when NOAH was formed in the early 2000s.

Kingston also said he would like to face Hiroshi Tanahashi or Yuji Nagata, if given the opportunity.

Well, I already have Ishii at STRONG. So, that was number one for New Japan [Shin Nippon Puroresu]. Hopefully, I said it right. Ishii was the guy," said Eddie. "Tanahashi, to me, saved puroresu at one time. Especially for New Japan. Of course, him. Nagata, of course, cause when that whole run he had with the IWGP title going sixty [minutes] with Chono and other matches, facing off against the shooters during a time period that was a little rough. But he was in there. He was a warrior. But for Forbidden Door, I dont know if it can happen, but if we talk about the Forbidden Door, itd be Akiyama. I know he doesnt work with New Japan or hes not with them, I know hes with DDT, but Forbidden Door, right? Thats what everybody [is]."

For now, Eddie remains hopeful that he will be on the card which will emanate from Chicago's United Center.

Yeah, again, I dont know anything about that. I just say, Hey, this is my dream match or Hey, this is the dude I want to work with. Either Chris Daniels comes back to see me and says, Tony says no or Tony said yes or Tony, when he gets excited, hell tell me yes, he said.

Of course, actually wrestling in Japan again remains a huge goal for Eddie Kingston who has not been in Japan in over a decade. During the interview with Sean, Kingston took the time to say that he wants to compete in the G1 Climax tournament, as he sees that tournament as his chance to live forever.

Yeah. The last time I was in Japan was in 2011 for Osaka Pro, at the time," he recalled. "Yeah, G1 has always been a goal. I was talking to somebody the other night, it was a youngin in the locker roomIm not gonna say whobut I was trying to explain that when I broke in my biggest goals were ECW, right before they closed; All Japan, at the time, before the NOAH split; and then New Japan and I wanted to be in all the tournaments. So, of course, the G1s always a goal. If not this year, then itll be a goal next year. For me, personally, the competitor in me, its not just about being invited to the G1. Its about actually winning. Not just doing good. Not just making it to the finals and other people would be happy about that. No, Im trying to live forever. Im trying to have my legacy live forever, so Im trying to win the whole thing. So G1. Theres your answer. To anyone listeningG1! Lets go.

For now, Eddie Kingston turns his attention to Tomohiro Ishii and their match at NJPW Capital Collision on Saturday, May 14. You can view the updated card here. Fightful will have coverage of the event on Saturday beginning at 8 p.m. ET

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Eddie Kingston Wants To Win An NJPW G1 Climax Tournament And Earn His Squared Circle Immortality - Fightful

‘Moon Knight’ Producer Teases New Kit for the Character’s Next Appearance – We Got This Covered

Moon Knight has plenty of tools and abilities to use that were shown during the Disney Plus series, but producer Grant Curtis has teased that we could see even more in the heros next MCU appearance.

During an interview with Phaze Zero, Curtis said that theyve only scratched the surface when it comes to weaponizing Moon knight, and theres a lot more to come.

Theres so much groovy stuff out there. We just scratched the surface with the crescent darts and the truncheons and all that Hes got a whole bag of tricks that we didnt even get into. So yeah, Id say when and if and where this character lands, hell have a new tool chest.

Its not clear when fans will see Moon Knight on their screens next as the show has not been confirmed for a second season nor has the character been confirmed to show up in any other Marvel Studios productions.

This being the case, the show was extremely well received and the character has quickly become popular so its likely we will see Moon Knight again.

While the heros toolset was limited during the series, there was still plenty of skills on display. These included the characters healing factor which Curtis explains, isnt the same as immortality. The producer likened Moon Knights current skillset to that of the Green Goblins.

Hes got a healing factor. He bounces back when he gets shot or stabbed, he heals. He doesnt heal right away, hes not immortal. If you get him the right way, hes gonna go down for good, but thankfully in our show, he got back up. He can glide, hes stronger than most people, hes faster. So its a little bit like a super soldier, like my pal, the Green Goblin from Spidey 1. Not quite the same thing but a little stronger, a little faster, heals, glides, kicks ass, takes name. The usual.

Moon Knight is available to stream in its entirety on Disney Plus right now.

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'Moon Knight' Producer Teases New Kit for the Character's Next Appearance - We Got This Covered

Liverpool vs. Tottenham: Premier League 2021-22 Preview and Team News – The Liverpool Offside

LIVERPOOL VS. TOTTENHAM HOTSPUR

Look, Ive got nerves for this one. The lads are so close to immortality you can almost taste it.

Liverpool dropped points against Spurs this season, and Antonio Contes Spurs have done the double over City (after winning on the opening day). That said, they last won at Anfield in 2011 (picking up two draws in that period, in 2016 and 2018 a draw would be just as bad, really).

In terms of away form, Spurs have played 19, won eight, drawn five, and lost six. Four of those six losses have come against big six sides (and West Ham) over the course of the season. They havent beaten any top six side away in the league other than, you know, Manchester City.

The atmosphere will be key, as we want to make it as hard for Spurs as possible. We know our lads will be up for it. They want the immortality even more than we do on their behalf.

When we played Spurs in December it was an exciting game for the worst reasons: Andy Robertson scored (he could have had a brace after going close in the opening minute), but was later sent off for a challenge on Emerson Royal a fair enough sending off though Harry Kane could well have seen red for a similar challenge prior to this.

The Reds played a much-changed side, with Tyler Morton and James Milner in midfield during the busy holiday period. Spurs had piled the pressure on, with both Ibrahima Konat and later even Alisson (uncharacteristically) not having their best games.

Liverpool will certainly be stronger in this matchup, though Spurs will as well: new boy Dejan Kulusevski has been massive for them, combining well with an in-form Son Heung-min (who is pushing Mohamed Salah for Golden Boot) and Harry Kane. Kulusevski got a breather in Spurs win against Leicester at the weekend, coming on to lodge two assists.

Given the pace (and chemistry) of the Spurs attack, Liverpool will need to look to limit service into them and to avoid complacency in the defensive line.

While Tottenham are certainly dangerous, their form is less consistent than their highlights might make you believe: they won against Leicester at home on Sunday after drawing to Brentford (A), losing to Brighton (H), and winning heavily against both Aston Villa (A) and Newcastle (H). Though these last two wins came in a stretch of four consecutive wins (West Ham at home and Brighton away), for the most part theyve struggled to put two wins together, largely alternating WLWLWL since January.

Tottenham have had more time to prepare and are fighting hard for a top four place. This will most definitely be a challenge, while City, coming off their disappointing (for them) Champions League exit, face Newcastle at home an entirely different proposition.

Alisson; Alexander-Arnold, Matip, Van Dijk, Tsimikas; Fabinho, Henderson, Thiago; Salah, Jota, Daz

Manager Jrgen Klopp has been making one or two changes each match to maintain squad fitness, and theres no reason to think anything will change now that the Reds have added a game to their schedule (in the small matter of the Champions League final).

Its possible that Andy Robertson could get a breather (despite being the main character in the reverse fixture), and Jol Matip could return to the side though Ibrahima Konats pace would be helpful in dealing with the Spurs front line.

Kostas Tsimikas, who came on to get a few minutes against Villarreal, could well feature here or against Villa at the weekend: notably, the manager has lately enjoyed subbing a player on late in one game to start him in the next (CC: Joe Gomez), and Tsimikas came on mid-week.

The same pattern could hold for Luis Daz, though the front three is anyones guess. Bobby Firmino has returned to full training, though Klopp hinted that he is likely to remain just training for a bit maybe a return to the lineup against Aston Villa? You would think Mohamed Salah will be asked to go again; whether we see Diogo Jota or Sadio Man through the middle is possibly a flip of a coin.

Given the threat that Tottenham pose, I would hope we see as close to a full-strength side as possible; this one feels like a major challenge.

Jurgen Klopp: [Tottenham] have speed like crazy up front, Harry Kane, what a player, they have a blind understanding (the front men). Its probably the biggest challenge for protection weve faced in a long time. We have to find a way to keep them calm as often as possible.

Antonio Conte: Jurgen Klopp is doing a great job with this team, especially for an English team to arrive at the end of the season to stay in the race for all the competitions you compete in, I think that its incredible because you can see Liverpools players. They run a lot and they dont have many injuries. Theyre doing a fantastic job. Their enthusiasm is 200% and you dont feel fatigue at this point.

We need to go there and play our game. We are in the race for a place in the Champions League and we have to find a way to get points in every game. We are playing against one of the best teams in the world away. We prepare like usual.

Referee: Michael Oliver Assistants: Stuart Burt, Simon Bennett Fourth Official: Martin Atkinson VAR: Darren England Assistant VAR: Marc Perry.

Kickoff is set for 7:45PM GMT/3:45AM EST tomorrow. In the meantime, The Liverpool Offside team will keep you updated with all of the team news and match buildup as it becomes available, along with providing a matchday liveblog and post-match recaps and reaction. If you want to join the discussion, sign up for an SB Nation account and have your say on the action as it happens.

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Liverpool vs. Tottenham: Premier League 2021-22 Preview and Team News - The Liverpool Offside

Extending the human lifespan – Bangkok Post

Next week, the American Academy of Anti-Aging Medicine (A4M) will organise its 29th Annual World Congress at The Venetian and Palazzo Resort in Las Vegas. Since 1992, A4M has been on a mission to redefine healthcare through longevity medicine in order to optimise vitality and extend the human lifespan.

But the question is do we really want to become super seniors or centenarians in a disruptive world?

Co-founder Dr Robert Goldman believes in the possibility of "practical immortality" with a lifespan of 120-plus years. Nine years ago, I met the ebullient anti-ageing physician at a conference organised by VitalLife Scientific Wellness Center and Bumrungrad International Hospital.

I asked him whether it's unnatural to stop the clock with anti-ageing medicine as the body isn't designed to last over 120 years.

"It's as unnatural as taking a plane,'' he said. "Because if man was meant to fly, he should have been born with wings.''

The fact is anti-ageing interventions are not something new and the search for the fountain of youth has been part of human culture and societies for millennia.

Dr Goldman asserts that there's nothing out of line with anti-ageing medicine and its utilisation to stretch the life span and enhance quality of life.

The demand for anti-ageing programmes is being driven by baby boomers who don't want to age the way their parents did.

Its comprehensive approach to wellness encompasses nutrition, dietary supplements, lifestyle modification, and controversial hormone replacement therapy.

One mechanism of ageing is a decline in hormone levels, which sends a chemical message to cells that this body is old and they start to die off. Hormone replacement therapy attempts to trick the cells to think that they're still young.

However, it's not a quick fix or a magic pill as it takes effort and focus in adopting an anti-ageing lifestyle and treatments.

Through very early detection, prevention and reversal of age-related diseases, this field of medicine aims to prevent illnesses and disabilities. In addition, advances in biotechnology will drive dramatic changes in anti-ageing medicine to accomplish practical immortality.

Around a century ago, a 40-year-old was considered to be an elderly person, and today those in their 70s are in the winter of life. The practical immortality concept proposes that in the future people will not be considered old until they are centenarians.

On the other hand, longevity can be earned without taking supplements and hormones. For example, Japan's nonagenarians and centenarians are proof of natural and healthy ageing through diet, exercise, way of life and cultural factors.

Accordingly, the anti-ageing movement has faced controversy and been accused of being pseudoscience and a business that prescribes dietary supplements, hormone injections, as well as other products and services.

Nevertheless, over the three decades, A4M has grown into a global community with alliances in countries including Thailand.

Next week, its Annual World Congress event is being held under the theme "The Next Chapter: Unmasking The Hidden Epidemic", and it will address many neglected health crises in a world stricken by Covid-19.

The pandemic has posed numerous challenges and changes as we focus on fighting infectious diseases and viral mutations. We aim to be survivors and not be afflicted by a deadly virus and its economic consequences.

Accordingly, the past two years have put many of us in a health-conscious mode and made us dependent on self-care due to lockdown.

It has probably changed many people's perspectives of the world and the meaning of life. Stuck in a crisis for two whole years, we may not even care about outliving turtles and just try to cope with current circumstances, which reinforce how uncertainty in life remains absolute certain.

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Extending the human lifespan - Bangkok Post

3 Former Eagles are one step closer to Hall of Fame induction – Inside the Iggles

The Pro Football Hall of Fame announced the names of 26 semifinalists on the eve of Thanksgiving and three former Philadelphia Eagles are one step closer to footballs version of immortality. Congratulations are in order for both longtime Eagles cornerback, one of the valedictorians of the Buddy Ryan era, Eric Allen and one of the more controversial players in team history, Ricky Watters.

Once January rolls around, fifteen finalists will be revealed in January. Kudos are also in order for senior finalist Cliff Branch and Art McNally, the latter being a contributor finalist. We also cant leave out another former Eagle and coach finalist, Dick Vermeil.

If hes inducted it will have been a long time coming for Eagles legend Eric Allen. NFL legend Deion Sanders even went to bat for him a little over a year ago, stating that the six-time Pro Bowler is long overdue to see his bust carved and placed in Canton, Ohio.

Allen has just under 800 tackles on his career resume along with 54 interceptions and nine defensive touchdowns. Hes a member of the Eagles 75th Anniversary Team and the franchises Hall of Fame.

Watters has long been forgiven for his For who? For what? comment. He spent three seasons in Eagles green, racking up 3,794 rushing yards, 1,318 receiving yards, and 32 total touchdowns in 48 career games.

Vermeil should need no introduction. He led the Philadelphia Eagles to their first-ever Super Bowl appearance and won more than 100 games in the City of Brotherly Love over seven seasons before returning from a long hiatus and leading the Saint Louis Rams to a Super Bowl victory. He too is in the Philadelphia Eagles Hall of Fame. His induction in Canton should be a no-brainer.

As it is every year, the Pro Football Hall of Fame Class of 2022 will be introduced during the NFL Honors special on the eve of the Super Bowl. Mark your calendars for that one. and watch it live on Fubo TV. It airs live on Thursday, February 10th at 9 p.m. EST on your local ABC affiliate.

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3 Former Eagles are one step closer to Hall of Fame induction - Inside the Iggles

Kambosos hopes to inspire fellow Aussies – The West Australian

Jubilant George Kambosos Jr is challenging Australia's other title aspirants to follow their dreams overseas as he savours his place in boxing immortality as an undisputed world champion.

Kambosos is the first Australian boxer in history to win three world-title belts in one fight after scoring a stunning upset win over previously unbeaten American Teofimo Lopez in New York.

The new unified lightweight world champion was rewarded for his unwavering dedication after more than four years without a fight in Australia.

Sacrificing precious family time with endless months training offshore in the Philippines with the great Manny Pacquiao and fighting in the US, UK, Greece and Malaysia, Kambosos is now the holder of the WBA, WBO and IBF straps.

"That's something these other guys in Australia who are making a bit of noise, they talk a big game and say they want to come over here but when it comes to booking that flight, they don't," Kambosos told AAP.

"So I don't understand how everyone wants to get behind them but they don't want to get overseas and chase it where it really happens, chase the big fish.

"It's a big difference when you're comfortable in your own zone and you need to leave your comfort zone and take the risk and achieve and get to the top and achieve what it is to become a world champion.

"They don't want to do it but Kambosos has done it and has been doing it for many years. We're here, we're fighting for the biggest thing Australia has ever seen.

"It's the pinnacle of the sport."

Blood streaming from a nasty cast above his left eye, Lopez claimed he'd been robbed despite being sent crashing to the canvas by Kambosos in the opening round - the first time since he professional debut five years ago the American had been floored.

"You're a hell of a fighter but I won the fight tonight. I want everyone to know that," Lopez protested.

"The referee raised my hand, I won tonight. I don't care what anybody said."

Not for the first time over the past week, Kambosos branded the vanquished champion "delusional".

"I won the fight fair and square. Take a look at your face. Take it like a champ, let's do it again in Australia," Kambosos said.

"Eighty-thousand fans in Australia, let's do it again."

After years of offshore toil, Kambosos won't be defending his titles anywhere but Australia and dedicated his victory to wife Rebecca, three young children and his late grandfather George.

"This is for my kids, my grandfather George Kambosos, who passed away two months away," he said.

"It's for my family, my wife, my grandfather. I know he's in the ring with me right now."

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Kambosos hopes to inspire fellow Aussies - The West Australian

The Old Guard: The Ages Of The Immortals (Including Andy) – News Nation USA

The Old Guardfeatures a group of immortal warriors, most of whom have been alive for centuriesbut how old are they exactly? The marketing material and movie itself offer several clues to the immortals ages. Charlize Therons Andy is the oldest, but most of her companions have had very long lives as well.

Directed by Gina Prince-Bythewood and based on the comic book seriesThe Old Guard, by Greg Rucka andLeandro Fernndez,the Netflix movie follows a team of warriors who have lived in the shadows for centuries, taking part in conflicts on whichever side they feel is right. The Old Guardis set in the modern-day, where a new immortal soldier Nile Freeman (Kiki Layne) joins the group after miraculously healing from having her throat cut. She is quickly initiated into the small group of warriors and learns how they have influenced history. While shes still learning about her new family, they come under threat from a greedy pharmaceutical executive called Steven Merrick (Harry Melling), who hopes to discover the secret to their immortality, bottle it, and put a price tag on it.

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Unfortunately for Merrick, hes not the first bad guy that the Old Guard has run into during their very long lifetimes. Heres a breakdown of when each member of the group besides Andy was born, and how old they are in the modern-day setting of the movie.

Whilethe movie form ofThe Old Guardkeeps Andys age ambiguous, it is known that she is the oldest member of the group. Her full name, Andromache of Scythia, refers to a Central Asian empire that ended in the second century CE, making Andy at least 1800 years old but likely older. A potential TheOld Guardsequel could expand the mythologyby exploring this, however the comics suggest that Andy is even older than her name suggests.

Rucka and Fernandezs comics depict Andy as being born circa 4500 BCE in the Western Steppe of Scythia. Andy developed immortality after being killed in battle, and led her tribe for hundreds of years. However, after centuries she left her position to seek justice and find other immortals. Andy even gives a precise age in the comics of 6732, meaning that she has been serving humanity for over six millennia.

Seen only in flashbacks and in The Old Guardsfinal scene, Quynhs (Veronica Ngo) age is perhaps the hardest to pin down out of all the immortals. In the comics shes called Noriko, and Andy recalls that they first metat the end ofAmr ibn al-As al-Sahmis conquest of the Byzantine Empire in 642, at which point Noriko had already been an immortal for a century. That puts her date of birth some time in early 500 AD,which would make her around 1500 years old during the events of The Old Guard.

However, in the movie its not specified exactly when or where Andy and Quynh met, except that Andy found Quynh when she was wandering through the desert, and that she was the first other immortal that Andy ever met. Many have speculated that Andy and Quynh will fight inThe Old Guard 2. In the comics, Andy met Lykon (Micheal Ward) before she met Noriko, and they fought together for two thousand years. Lykon also appears briefly in a flashback in The Old Guard, with Andy and Quynh both being present at the time of his death. If Quynh has been aged up in order to have been born before Lykon, she could actually be several thousand years old during the events of the movie. Hopefully,audiences willlearn more about her backstory including her age in The Old Guard 2.

According to his character poster, Joe (Marwan Kenzari) was born in 1066, making him 954 years old at the time The Old Guard takes place. Originally called Yusuf Al-Kaysani, Joe was a Muslim warrior during the First Crusade, who met the love of his life on the battlefield and killed him. However, fate chose them asthe next immortals to join the Old Guard, and after repeatedly slaying each other they realized that neither they nor the enemy soldier could be killed at which point their enmity turned to love.

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Younger than Joe by only a few years (which grew even less significant as the centuries pass), Nicky (Luca Marinelli) is 951 years old during the events of The Old Guard, based on a character poster that gives his year of birth as 1069. This means that he would have been in his late twenties 30 at most the first time he died. Like Joe and Andy, Nicky changed his name at some point from Nicol of Genoa to the more common name ofNick Smith, in order to aid his anonymity. This period of the Crusades has been a popular setting for movies as well as video games like Assassins CreedandCrusader Kings.Hailing from the city of Genoa, in what would later become the unified country of Italy, Nicky fought in theFirst Crusadeuntil he fell in love with one of the enemy, and instead began fighting new battles alongside him. After settling their differences, Joe and Nicky both met Andy and became part of the Old Guard alongside her and Quynh.

The baby of the group (at least, until Nile comes along), Booker (Matthias Schoenaerts) is 250 years old during the events of The Old Guard, with his character poster marking his year of birth as 1770. His treacherous actions make it unclear whether hell return for a potentialThe Old Guard2. Born Sebastien le Livre (his nickname comes from his surname, which is French for Book), Booker was a soldier under Napoleon who deserted during the campaign into Russia. He was caught and hanged, but came back to life still hanging from the noose, being 42 years old at the time of this first death in 1812. As he lived on without ageing, Booker experienced the trauma of watching his sons die and being helpless to stop them, even as they grew to hate him for not sharing his gift of immortality. Being a young immortal,the 100-year penance that Booker is sentenced to at the end of The Old Guard would still be a significant amount of time for him.

A pivotal part of The Old Guards cast is Nile, who acts as a viewpoint character. A brand new member of the Old Guard, Nile Freeman is 26 years when she dies for the first time, having her throat cut while trying to save the life of a man she has just shot. After she wakes up in the infirmary without a mark to show for her injury, shes shunned by her fellow soldiers and about to be sent away for some probably very unpleasant testing when shes abducted by Andy. Nile has a military legacy to uphold, with her father having been killed in action, but also has a family that shes at first keen to return to. By the end of the movie, however, she has decided to stick with Andy and the other immortals, having seen the good that theyve managed to do in the world.

There are plenty of unanswered questions from The Old Guard that could be addressed in The Old Guard 2, and the precise ages of Andy and Quanh are among them. The sequel could also fill in the centuries of backstory that each of the immortals have, making their ages very important for the franchise going forward.

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