1. Biochemistry

Category Archives: Biochemistry

MBB Curriculum – Biochemistry

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Learning Goals for the MBB Major:

1. Students should demonstrate an understanding of the knowledge that is needed to begin biomedical research and that is required for post-graduate exams and studies.

2. Students should demonstrate the ability to find and evaluate information about specific biological systems or problems.

3. Students should demonstrate the ability to design experiments and critically analyze data.

4. Students should demonstrate the ability to communicate their research and findings orally through seminar and poster presentations and through written research papers.

This is the basic core curriculum that is required for all majors in the Division of Life Scienes.

119:115, 119:116, and 119:117

160:161 and 160:162 - or - 160:163 and 160:164

640:151-152 - or - 640:135,138

160:309 - or - 160:311

MBB students must choose between one of two course options for the major.

Course Option I is for students with a strong background in math and that may be pursuing research and graduate work in the physical biosciences. This course option requires a year of Physical Chemistry courses offered by the Chemistry Department. A prerequisite for Physical Chemistry is Multi-variable Calculus. Students taking this option with 12 credits or more of research are required to take one MBB elective. Students with less than 12 credits of research are required to take two MBB electives in addition to the Physical Chemistry and Calculus courses. Note: Students taking course Option I fulfill the requirements for a Minor degree in Chemistry.

Course Option II is for students with broad interests in molecular biology and biochemistry. Students taking this option with 12 credits or more of research are required to take three MBB electives. Students with less than 12 credits of research are required to take four MBB electives.

All MBB students are required to perform an independent research project under the direction of a faculty advisor. Students may choose to work with faculty member from any of a number of RutgersSAS, SEBS, or Medical School departments. Registration in research courses is by special permission only. Students must fill out aSpecial Permission Form for Undergraduate Researchand have it signed by their research advisor and MBB academic advisor before they can get a special permission number from the MBB Department Undergraduate Secretary, Shalene Montgomery. Research is required in the senior year, but students are strongly encouraged to start their research in their sophomore and junior years and during the summers if possible. All students doing research must submit a paper to the department office describing the work done, before credit will be given.

Lab Option I: Students need a total of 12 or more credits of research.

Lab Option II: Students need only 6 credits of research and must take an another MBB elective in addition to the required MBB elective for Course Option I (Calc. III, Physical Chemistry, and a MBB elective) or the three electives required for Course Option II (3 MBB electives or 2 MBB electives and a DLS elective).

Non-Lab Option:Non-lab students must take Literature Research in MBB (694:489/490) for6 credits.

The number of electives required for the different combination of the Course and Lab Options is shown below.

Course Option II (MBB electives)

Lab Option I (12 or more research credits)

1 MBB Elective

2 MBB Electives and 1 MBB or DLS Elective

Lab Option II (6-11 research credits)

2 MBB Electives

3 MBB Electives and 1 MBB or DLS Elective

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MBB Curriculum - Biochemistry

Glutathione Industry 2019: Attractive Market Opportunities with Top Key Players- Kyowa Hakko Bio, Shandong Jincheng, KOHJIN Life Sciences, Shenzhen…

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AMR(Ample Market Research) present new market insight report on Glutathione Market.

Glutathione market insight is with 123 pages and comes under Chemicals & Materials.

Recently we came across slowdown in global economic growth, the Glutathione market industry has also suffered a certain impact but still maintained a relatively optimistic growth in the past four years (2014-2018).

AMR research analysts team believes that in the coming years, Glutathione market size will be increased or further expanded.

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Glutathione Market: Key Players/Manufacturers Analysis

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Revenue, Gross profit, Interview record, Business distribution, etc., these important informational data will help the consumer know about the Glutathione Market competitors better with their strategies, recent developments and much more.

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Kyowa Hakko Bio, Shandong Jincheng, KOHJIN Life Sciences, Shenzhen GSH Bio-tech, Kaiping Biochemical Pharmaceutical, Gnosis SpA

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Ample Market Research provides comprehensive market research services and solutions across various industry verticals and helps businesses perform exceptionally well. Our end goal is to provide quality market research and consulting services to customers and add maximum value to businesses worldwide. We desire to delivery reports that have the perfect concoction of useful data. Our mission is to capture every aspect of the market and offer businesses a document that makes solid grounds for crucial decision making.

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Glutathione Industry 2019: Attractive Market Opportunities with Top Key Players- Kyowa Hakko Bio, Shandong Jincheng, KOHJIN Life Sciences, Shenzhen...

Biochemistry courses for undergraduate students …

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BIOCHM 1090 - Introduction to Biochemistry

Course detail

Units: 3 Grading basis: A/F Lecture: required Department consent: required

Description

Fundamental concepts in biochemistry and molecular biology: structure function relationships, reactivity, thermodynamics, gene expression. Professional skills for biomedical careers. Primarily for freshman and sophomore biochemistry majors. Prerequisite: departmental consent and Chemistry 1320 or concurrent enrollment.

Course detail

Units: 2 Grading basis: A/F Laboratory: required Department Consent: required

Description

Techniques course involving analytical experiments with carbohydrates, lipids, proteins, nucleic acids; use of instrumentation in biochemistry; purification and kinetics of enzymes, PCR and cloning. Prerequisite: departmental consent and Biochemistry 1090.

Course detail

Units: 3 Grading basis: A/F Lecture: required Recitation/seminar/discussion: required

Description

Survey of modern biochemistry and biotechnology. Structure and function of DNA, proteins, lipids and carbohydrates. The role of biopolymers in life processes and everyday living is emphasized. Prerequisite: Chemistry 1100 or 1310 or high school chemistry.

Course detail

Units: 3 Grading basis: A/FLecture: required

Description

Biotechnology in a social context covers three areas: introduction to terminology and concepts, specific biotechnological applications to modern problems, and ethical questions.

Course detail

Units: 2 Grading basis: A/F Lecture: required

Description

The function of biochemical macromolecules is directly related to their structure. The three-dimensional structures of proteins, nucleic acids, polysaccharides and membranes are each explored in the context of their functions and their microenvironments within living organisms. Prerequisites: Organic Chemistry I or concurrent enrollment.

Course detail

Units: 2 Grading basis: A/F Lecture: required Laboratory: required

Description

The laboratory experiments include DNA isolation, DNA cloning, PCR, plasmid transformation, protein expression, affinity-tagged chromatography, SDS-polyacrylamide gel electrophoresis, enzyme isolation, enzyme assay, buffer preparation, and Michaelis-Menten kinetics.

Course detail

Units: 3 Grading basis: A/FLecture: required

Description

Survey of biochemistry; static/dynamic aspects of carbohydrates, lipids, proteins, nucleic acid. Discussion of metabolic pathways, energy production, and metabolic regulatory mechanism. Prerequisite: Chemistry 2030.

Course detail

Units: 3 Grading basis: A/F Lecture: required

Description

First semester of comprehensive biochemistry course: metabolic pathways, amino acids/proteins, carbohydrates, lipids, nucleic acids, kinetics, energy requirements, metabolic regulation in living cells. Prerequisites: Chemistry 2110 with a grade of C- or better is strongly recommended.

Course detail

Units: 3 Grading basis: A/F Lecture: required

Description

Second semester of a comprehensive biochemistry course, including metabolism of carbohydrates, fatty acids, steroids, amino acid synthesis and metabolism, molecular genetics, hormones, photosynthesis and integrated metabolism. Prerequisite: Biochemistry 4270 with a grade of C- or better is strongly recommended.

Course detail

Units: 3 Grading basis: A/F Lecture: required

Description

To present fundamental principles of physical chemistry, in the context of the structure and function and biological macromolecules. Prerequisite: Biochemistry 4270 completion or concurrent enrollment and Math 1700.

Course detail

Units: 3 Grading basis: A/F Lecture: required

Description

Employs the use of computer-based interactive molecular graphics and sequence analysis software to analyze the three dimensional structures of macromolecules. Prerequisites: Completion of Chemistry 2110 with a grade of C- or better is strongly recommended.

Course detail

Units: 1-3 Grading basis: A/F Independent study: required Department consent: required

Description

Independent study of biochemical topics under the guidance of individual faculty members. Together the faculty mentor and student design the project. This is not for laboratory projects. Must have faculty member identified to enroll. May repeat course.

Course detail

Units: 3 Grading basis: A/F Lecture: required

Description

Same as Biological Science 4460. Cancer, cell biology, genetics, biochemistry. Prerequisites:Biochemistry 4272, Cell Biology 2300, Genetics 2200.

Course detail

Units: 2-3 Grading basis: A/F Independent study: required Department consent: required

Description

Individually directed laboratory research for upperclass students under faculty supervision. Faculty mentor must be identified to obtain consent number. Course may be repeated.

Course detail

Units: 5 Grading basis: A/F Lecture: required Department consent: required

Description

Students will learn the basics of working in industry while learning the necessary technical skills and philosophical theories to complete a summer internship at ABC Laboratories in Columbia.Prerequisites: Biochemistry 4270, Biochemistry 4272, Chemistry 2100, Chemistry 2110, Chemistry 2130, Chemistry 3200

Course detail

Units: 1 Grading basis: A/F Lecture: required

Description

Discuss journal papers dealing with current topics of research, techniques, status of field, importance of results. Students report on completed undergraduate research projects.

Course detail

Units: 5 Grading basis: A/F Laboratory: required Lecture: required

Description

Techniques course involving analytical experiments with carbohydrates, lipids, proteins, nucleic acids; use of instrumentation in biochemistry; purification and kinetics of enzymes. Prerequisites: Completion of both Chemistry 3200 and Biochemistry 4270 with a grade of C- or better is strongly recommended.

Course detail

Units: 2-3 Grading basis: A/F Independent study: required Department consent: required

Description

Individually directed laboratory research for upper-class honors students under faculty supervision. Faculty mentor must be identified to obtain consent number. Course may be repeated.

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Biochemistry courses for undergraduate students ...

INBI Shaker Club from A.N.Bach Institute of Biochemistry of RAS, Moscow Russia – Video

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INBI Shaker Club from A.N.Bach Institute of Biochemistry of RAS, Moscow Russia
INBI Shaker Club made by the A.N.Bach Institute of Biochemistry of RAS, Moscow Russia Video made for the Competition The Art of Shaking operated by Kuhner Sh...

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INBI Shaker Club from A.N.Bach Institute of Biochemistry of RAS, Moscow Russia - Video

Liver Biochemistry: The Role of Cholestasis in Increased Serum Levels of Alkaline Phosphatase – Video

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Liver Biochemistry: The Role of Cholestasis in Increased Serum Levels of Alkaline Phosphatase
The Role of Cholestasis in Increased Serum Levels of Alkaline Phosphatase. Video from Tasha Obrin vimeo.com/95798030 creativecommons.org/licenses/by/3.0/

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What Is The Definition Of Biochemistry Medical Dictionary Free Online – Video

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What Is The Definition Of Biochemistry Medical Dictionary Free Online
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What is Biochemistry and Why it Matters – Nanalyze

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If youre a regular reader of Nanalyze, youll know that were big fans of the work that Bryan Johnson of Kernel is doing, essentially trying to enable read/write access to the brain. In one of his interviews, he remarks thatever since we first booted up a cell with human engineered DNA, we entered a new era that according to his mentor Peter Diamandis, 99.9% of people have no idea weve entered.

What theyre referring to is the fact that humans have essentially discoveredthe Engines of Creation that Eric Drexler was talking about. While everyone is running around slinging political mud at each other like a bunch of primitive monkeys, mankind is working on one of the most transformational technologies that may ever be invented. Its called synthetic biology and its why everyone should have a basic understanding of biochemistry.

When you werechoosing your major in college, you either had your mind set on a particular field already or you needed to peruse all thesubject areas to see what sounded like a good fit. Each subject area will have a certain stereotype associated with it.Some fields sound boring, like electrical engineering or accounting. Some fields sound inherently difficult, like physics or mathematics. Other fieldsyou may not have an idea of what they do because they never sounded compelling enough to research. Thats the case for us withbiochemistry and thats why we thought, as investors, we should edify ourselves on what turned out to be a very relevant and interesting area of the sciences.

If we lookup the basic definition of biochemistry, this is what we get:

the branch of science concerned with the chemical and physico-chemical processes and substances which occur within living organisms.

So its a bit different from chemistry since itsall about the study of chemical processes in living organisms. Heres why it came about according to the American Chemical Society:

Biochemistry emerged as a separate discipline when scientists combined biology with organic, inorganic, and physical chemistry and began to study how living things obtain energy from food, the chemical basis of heredity, what fundamental changes occur in disease, and related issues.

The most basic premise is that you are using living things to take INPUT X and turn it into OUTPUT Y in the most efficient manner possible. If you think about humans as a complex organism, we are able to utilize the equivalent of several pounds of vegetative material to power one of the most complex and amazing machines on the planet. The problem with us though, is that the output from that process has no real use except maybe as fertilizer.

In the U.S. alone, there are approximately 13,500 chemical manufacturing facilities in the United States owned by more than 9,000 companies. These are giant operations which consume a great deal of energy, require a large workforce to maintain, and generate a great deal of pollution. Imagine how much energy and effort goes into building complex mechanical contraptions like this:

Your bog standard chemicals plant

Think about how inefficient these plants have been over the decades as theyve sat there consuming resources and feeding the mass consumerism that we enjoy in todays modern society.Now think about this. What if instead of using these inefficient plants, we engineered biological organisms to produce chemicals by modifying the DNA of the organisms so they did what we needed.The simplest way to think about it is to visualize those punch-cards we used our dads used back in the day. If thats beyond your time, heres what an IBM punch card used to look like:

In the olden days of mainframe computing, we used apunch card like the ones seen above toprovide the computer with a set of instructions. With DNA, its pretty much the same idea except its like havingprecisely these many punch cards:

The above pile of phone books shows roughly the amount of data that a strand of DNA contains, approximately 700gigabytes of data. DNA is one giant punch card that just recently weve been given the hole punch for. That hole punch is called gene editing and its been all over the news lately due to a nasty lawsuit that will determine who has the commercial rights to one of the most exciting discoveries known to man. This biological hole punch called CRISPR will soon let us change every single characteristic we like for any organism and then boot it up so we have our own little biological nanobots doing things for us.Since organisms are the most efficient biological factories (or engines of creation) known to man, it makes sense that we should be modifying them to produce as many industrial chemicals as possible.

The use of synthetic biology for creating things like biofuels (primarily)was off to a rough start as evidenced by the cratering stocks involved in this space like Amyris (NASDAQ:AMRS) and Gevo (NASDAQ:GEVO). Fast forward to today and the potential is even greater but a different model is now being applied. Now you have nanobot factories like Ginkgo Bioworks and Zymergen that areusing artificial intelligence, robotics, and gene editing in order to create little tiny biological chemical manufacturing plants.

Lets say youre a chemical plant that uses a particular enzyme in your production process. You can then go ask Ginkgo or Zymergen to take that enzyme you use and modify it over millions and millions of iterations using the principles of biochemistry. The speed at which they can perform this process has just hit hockey stick growth as seen below:

The end result is an optimized enzyme that meets your requirements and saves you millions of dollars. Startups like this that are using synthetic biology to completely overhaul the industrial chemical manufacturing process are as secretive as you would expect. While we may not have detailed information about what theyre working on, we can take a look at some examples of startups that are using biochemistry and synthetic bioogyin order to create some pretty complex and useful outputs from some basic interesting inputs:

These startups are backed by some big dollars and some big names, however the future business model is a bit hazy here. Will we have the chemical companies going directly to the creators of the synthetic organisms like Ginkgo or will we have startups like the ones mentioned above doing all the production and selling to the chemical companies, only to get acquired once the technology is proven? The one thing that we can be sure of here is that the large chemical producers will profit fromthe use of biochemistry, synthetic biology, and gene editing, consequently we can expect shareholders in these companies to reap the benefits.

If you have children, you maywant to steer them towardsbiochemistry as a major becausethere is a lot of work to do. According to Statista, total revenue of the global chemical industryin 2015 exceeded 5 trillion dollars. This morning when youre tempted to talk about how much political mudslinging there was at the Oscars or who wore the cutest dress, do the world a favor and tell someone how exciting biochemistry is instead.

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What is Biochemistry and Why it Matters - Nanalyze


  1. Biochemistry