Last week, at our first Labiotech Hangout,Philip had a chat with James Peyer, a partner at Apollo Ventures, to ask a few questions about how biotech istackling the anti-aging space.

For a long time, the anti-aging field has not seen much innovation,both due to a lack of scientific know-how as well as a lack of confidence on the part of pharma and regulatory agencies. Yet, in the past years, the field has started to turn into one of the most hyped areas in biotech, marked by the launch of companieslike Unity Biotechnology, which recently raked in $116Mfrom big names like Jeff BezosorCalico, which was co-founded by Google in 2013.

James Peyer from Apollo Ventures, a VC that focuses on biotechs in the age-related disease space, talked to Philip abouthow biotech is trying to solve the challenges of anti-aging, where the field is moving and how the first anti-aging therapies could enter the clinic within the next two years.

Referring to a review article on the hallmarks of aging, Peyer explains thatWithin the last 5 years, our understanding has gone from theory and hypothesis-driven to really coalescinga strong data-driven knowledge base.While there is no drug out there yet that is approved as an anti-aging treatment, James comments that The geroscience space has at least 80 mutations or chemicals that have been shown with some level of conviction to extend the healthylife span of a mouse.

However, the challenge will be to bring these compounds into the clinic. Anti-aging therapies are preventative medicines, meaning that the treatment is given before the actual occurrence of age-related disease so how do you run a clinical trial for such medicines?

Peyer mentions a group of scientists from Albert Einstein College of Medicinein New York that have been piloting such a preventative medicine study with a 7-year trial, totest whether the generic drug metformin can delay the onset of age-related conditions.This model of a 7-year clinical trial though, thats not really something that can be easily translated to a commercial model with a patented drug,he explains.

But whats gonna come out of those trials in the next 5-10 years are biomarkers that will give us a hint on whether or not adrug is working to reduce the risk of age-related diseases, and then that biomarker could be used in future trials,Peyer argues.

Apollo is following a slightly different path, though, as Peyer explains.The VC aims to go after geriatric syndromes, such as osteoarthritis, that are actually treatable medical conditions. Youll be really focussed on one indication thats a real clinical opportunity and move that towards the clinic just as you would with a traditional oncology drug or osteoarthritis drug.

Thats the opportunity that Apollo is really excited about and then, of course, there is the vision in the longer term that those two paths () will come together and create a world where we can actually do preventive clinical trials,Peyer adds.

Reflecting on who is buying in on that vision, Peyer says that the big players that are now coming into the area are technology players like Jeff Bezos or Google (). The internet space has attracted so much investment but the return profiles in this space actually look much worse compared to biopharma both in the US and the EU.

The biopharma space is actually just kicking ass right now! So when you see numbers like that and youre a tech investor it makes sense to make some moves.

Check out the video to hear more about which companies are leading the fieldandwhere Apollo is heading.

Shutterstock.com / BrunoWeltmann and Rustle

Merken

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How Biotech Will Make Us Live Longer - Let's Talk Anti-Aging - Labiotech.eu (blog)

Anti-Aging Medicine: Advances in Hormone Replacement is a two-day course. Course Schedule: Agenda Faculty: Louis Cady, MD

2017 Course Discounts Early Bird Discount in San Antonio: Register by May 3rd and enter code EBJUN to save $100

Course Credits Earn up to 16 AMA PRA Category 1 credits and AAFP Prescribed Credits

2017 Course Location Information June 2-3 - San Antonio - SOLD OUT - email to be added to the

Rates as low as $219 per night (resort fee waived) through May 5, 2017, or until sold out. Mention you are with TAFP (Texas Academy of Family Physicians) to receive the group rate. Group Code: TAE17A

Anti-Aging Medicine: Advances in Hormone Replacement Course Description

This anti-aging procedural training course utilizes a case study approach designed to help physicians and practitioners successfully and knowledgeably treat their age management patients. This intense 2 day mini-residency teaches everything you should know about hormones, the various types of hormones, both good and bad, problematic, and life-saving, synthetic (non-human) vs. pharmaceutical bioidentical (human identical) vs. compounded (human identical but not FDA tested or approved). Youll get the real nuts and bolts needed to prescribe hormone replacement therapy (HRT), which ones to use and which ones to avoid, how much, when, and why. Youll learn about monitoring and adjusting HRT through literature presentations, case studies, and open discussions. Emphasis is placed on understanding the difference between normal and optimal levels of hormones based on our medical studies.

Day two involves extensive review of 100 cases that involve laboratory evaluation, prescribing, adjusting, troubleshooting, and discussing various hormone therapies for different scenarios for both men and women. Your practice of hormone replacement therapy will be based on peer-reviewed medical research and a wealth of clinical experience. This is the most comprehensive course taught on anti-aging medicine training, designed to give you practical information and skills that you can use on a daily basis. The curriculum is an evidence-based program on preventive medicine designed to enhance your diagnostic and prescribing skills when optimizing hormones for both men and women.

Although most clinicians are fully aware of the need to replace hormones in cases of sub-normal hormone levels, most have not been trained to optimize hormone levels if the baseline hormone level is normal. Many participants frequently inquire why a patient is treated with various hormones when the baseline lab test indicates normal. Just as confusing is the realization that the medical literature supports that normal is simply not optimal. A multitude of studies support optimization of all hormones regardless of the baseline levels, both for maintenance of quality of life and for future health benefits. In addition, the medical literature demonstrates that optimization of hormones results in relief of symptoms, improvement in well-being, and a decrease in morbidity and mortality by attaining levels in the upper range of normal. It is imperative that practitioners understand both the need and benefit for optimization, what levels are considered to be optimal, as well as have command of the literature that supports it. One important aspect of this course is the extensive review of the medical literature that provides the credence and support as to why we optimize with certain hormones as well as avoid the use of non-isomolecular hormones. Remember that normal is definitely not optimal when it comes to hormone replacement and this applies to both men and women.

This Live activity, Anti-Aging Medicine: Advances in Hormone Replacement, from 01/01/2017 - 12/31/2017, has been reviewed and is acceptable for up to 16.00 Prescribed credit(s) by the American Academy of Family Physicians. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Learn more about our Accreditation

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Anti-Aging Medicine & Hormone Replacement CME

FOX31 Denver

Balance Your Mind and Body with a Natural Approach to Anti-Aging FOX31 Denver Doctor Carrie Louise Daenell is an internationally recognized anti-aging expert who speaks all over the world on the topic of natural medicine. She joined us this morning to share how to naturally balance the 40's mind and body through supplementation ...

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Balance Your Mind and Body with a Natural Approach to Anti-Aging - FOX31 Denver

Connect Meetings has launched an event specifically for medical stakeholders and continuing medical education providers to take place Oct. 24-26 in Cincinnati.

Hosted by Connect at the Renaissance Cincinnati Downtown Hotel, Connect Medical is a hosted-planner, appointment-only program and education conference.

The event brings together the most active planners, suppliers and experts in medical meeting planning for three days of general sessions, roundtables, workshops, preset appointments and quality networking.

"We produce over 60 events a year," said Doreen Brown, CEO of the American Academy of Anti-Aging Medicine.

She added, "Finding the right location and the right vendor partners for our physician audiences is a key factor in our growth and success. Medical audiences have unique requirements. We are looking forward to attending Connect Medical to learn from our peers."

Connect Medical features an emphasis on high-level education relevant to medical event planners.

Presented by established authorities in the field of event planning, these sessions offer attendees thought-provoking deep dives into strategies for developing successful events and advancing their careers.

During the Marketplace session of Connect Medical, planners and sellers meet in preset, scheduled appointments specific to their meetings' needs, exchange RFPs, arrange future site visits and book events.

For more information on Connect Medical please visit ]]> connectmedicalmeetings.com]]> .

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Connect Medical Will Launch in Cincinnati in October - TSNN Trade Show News (blog)

Posted on May 23, 2017, 6 a.m. in Longevity Aging Diet

Research analysis finds that cutting calories works at a physiological level to slow biological aging.

The study was lead by Daniel Belsky, Ph.D. an assistant professor of medicine at the Duke University School of Medicine. Previous research has shown that calorie restriction hinders the aging process in mice, worms, and flies. The question is to what extent such restriction has on the biological aging process in human beings. Biological aging is best defined as the slow but progressive deterioration of the human body's systems over time. If the biological aging rate can be slowed through intervention, it might be possible to delay or prevent the onset of numerous age-related disabilities and diseases.

About the Analysis

Belsky and her team of researchers studied data available to the public from a trial known as CALERIE. The National Institute on Aging conducted this study involving 220 individuals. They were randomized for a calorie restriction of 25 percent or allowed to maintain their current dietary intake. The calorie restriction group was comprised of 145 people. Their calories were reduced by 12 percent across the two-year study. The other group, in which calories were not restricted, was comprised of 75 individuals. The research team studied data from both groups at the beginning of the study. Follow-ups took place at the one-year point as well as the two-year anniversary.

The Results

One method calculated the biological age for participants according to their chronological age as well as the biomarkers that gauge the function of the liver, kidneys, immune system, metabolic system, and cardiovascular system. Hemoglobin levels, systolic blood pressure, and cholesterol were also accounted for. At the beginning of the study, both groups had similar biological ages as determined by the measure described above. The average biological age of the participants was 37 while the average chronological age was 38.

Once the one-year follow-up point was reached, those in the restricted calorie group had an average biological age increase of 0.11 years. The participants who continued their normal dietary intake experienced an average biological age increase of 0.71 years at the one-year follow-up. The difference between these groups was statistically meaningful, showing that restricting calories really did deter the biological aging rate.

The research team also performed another analysis that quantified biological aging as the level of physiological deviation from a benchmark defined by young and healthy individuals from a distinct data set. At the beginning of the trial, the maintenance and calorie-restricted groups deviated the same level on average from the benchmark point. However, at the one-year and two-year follow-up points, the average deviation among the maintenance group stayed the same. The group in which calories were restricted gradually became more similar to the healthy and young benchmark reference point.

The findings were consistent with the mitigated aging researchers found in the group with restricted calories when the biological age calculation method was applied. Interventions to offset or control aging are at the center of medical research.

Study Importance

This was the first study to gauge whether the restriction of calories could mitigate measured biological aging in human beingsin a randomized setting. This study applied the measures of physiologic age described above and demonstrated their value as well as the apparent value provided by restricting calories to slow the aging process. The results suggest a template to develop and study therapies meant to copy the effects of restricting calories to ward off chronic diseases.

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Curbing Calories Slows Aging | Worldhealth.net Anti-Aging News - Anti Aging News

Researchers from the University of California in San Diego and the University of Minnesota have discovered a link between neurological behaviors in Ecuadorian children and pesticide use during flower growing seasons. Their findings were published in the medical journal NeuroToxicology in May of 2017. Dr. Jose R. Suarez-Lopez Ph.D., an assistant professor at the University of San Diego in the Department of Family Medicine and Public Health, served as first author of the study.

Testing of Children in Agricultural Areas

Ecuador produces a large portion of the worlds cut flowers. The industry relies on pesticides to ensure successful harvests. Previous research using animals as test subjects suggested a link between temporary neurological disorders and pesticide exposure.

The research team tested 308 Ecuadorian children between the ages of 4 and 9 years of age who live near, but do not work in, flower producing areas. Behavioral and blood tests were conducted before peak production for the Mothers Day holiday, and within 100 days after harvest.

Results show that children tested shortly after the harvest ended displayed lower attention spans, less self-control, inferior hand-eye coordination, and problems perceiving and interacting with visual stimuli when compared to children tested later.

The authors of the study conclude that exposure to pesticides causes a short-term decline in neurological functions. According to Dr. Suarez-Lopez, this is of concern due to timing. The growing season corresponds with end-of-term testing in schools. Children suffering from temporary impairment due to pesticide exposure may receive lower scores on important academic exams. These lower scores may then affect their ability to qualify for certain opportunities in higher education or the job market.

The Effects of Agricultural Poisons

Newborns who are exposed to agricultural chemicals are known to have higher risks of certain neurological conditions, such as attention-deficit hyperactivity disorder (ADHD), and abnormalities in reflex, psychomotor, and mental function development. The effects are more prevalent in boys than girls. The short-term disorders detailed in the published study are in addition to these known, long-term effects.

The chemicals in question contain a substance called organophosphate, which is used to destroy pests on flowers before export. In the human body, organophosphates inhibit the actions of the enzyme acetylcholinesterase (AChE). AChE regulates acetylcholine, a neurotransmitter that allows nerves in the body and brain cells to communicate. Organophosphates are also known to destroy neurons and supporting brain cells. Low Ache levels are associated with impulsive behaviors and low attention spans and scores on memory tests.

The ESPINA Study and Future Research

The ESPINA study is an on-going study that examines the effects of agricultural toxins on children in Ecuador. The study published by Dr. Suarez-Lopezs team is part of this larger effort to understand how environmental pollutants affect the long-term development and welfare of young people growing up in agricultural areas.

Researchers believe their findings prove that exposure to certain pesticides alters cognition, and the ability to learn and interact socially in children. Dr. Suarez-Lopez suggests that a better understanding can be achieved by repeating the tests with a larger sample group. In addition to conducting blood and behavioral tests before and after harvests, an additional test would be conducted during the harvest period, when exposure to agricultural pesticides peaks.

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Flower Pesticides Linked to Neurological Problems - Anti Aging News

Researchers have discovered an antioxidant that may potentially help protect cardiovascular functions in patients with diabetes. Details on the study were presented at the 2017 Arteriosclerosis, Thrombosis, and Vascular Biology and Peripheral Vascular Disease Scientific Sessions in Minnesota. The American Heart Association sponsored the event. Ji-Yao Ella Zhang Ph.D. from the Whitaker Cardiovascular Institute at the Boston University in Massachusetts led the team. Dr. Naomi M. Hamburg, doctor of Cardiology and Internal Medicine, was the studys senior author.

Resveratrol

The compound Resveratrol is an antioxidant found in grape products such as juice and wine, certain berries, peanuts, and cocoa. The compound belongs to a class of chemicals known as polyphenols, which are antioxidants that come from plants. Previous research has suggested that polyphenols may help improve cardiovascular functions and reduce damaging inflammation.

Stiff arteries are a byproduct of the aging process. Those affected by diabetes experience premature arterial aging. Hardened arteries increase risks of experiencing a heart attack, stroke, and high blood pressure.

Previous studies using animals as test subjects has shown that Resveratrol helps reduce hardening of the aorta. The aorta pumps oxygenated blood from the heart to the rest of the body. The studies show that Resveratrol activates the SIRT1 gene, which is associated with slower aging processes. The team at Boston University wanted to explore if the compound had the same effect on humans.

Clinical Study

Fifty-seven participants were chosen for the study. The average age of participants was 56 years. All patients had type II diabetes and had a body-mass index (BMI) that indicated obesity.

Patients were given 100 mg doses of Resveratrol daily for a two-week period. The dosage was then increased to 300 mg for another two weeks. After a two-week washout period, the participants were given a placebo for a total of 4 weeks.

Most of the participants saw no changes in arterial stiffness. However, a subgroup of 23 patients with particularly high arterial stiffness saw a 9% decrease with the 300 mg dose and a 4.8% decrease with the 100 mg dose. The placebo treatments seemed to increase overall arterial stiffness.

Study Conclusions

While the exact mechanism is not known, researchers conclude that Resveratrol treatment reverses abnormalities in blood vessels caused by aging, obesity, and diabetes. The compound appears to improve structural issues in the aorta but does not relax blood vessels. This means that Resveratrol treatment benefits diabetes patients more than those without this condition.

Further study is necessary to confirm these findings.

Original post:
Resveratrol May Benefit Diabetics' Cardiovascular Health - Anti Aging News

Posted on May 17, 2017, 6 a.m. in Functional Foods GI-Digestive Inflammation

Researchers investigating the gut microbiome recommend that just as you should eat fiber every day, you should also follow suit with fermented foods.

Just about everyone loves yogurt. It tastes amazing, has a lovely texture and provides a number of health benefits. Yogurt is one of the many fermented foods that is fantastic for gut health. Researchers at the University of Nebraska-Lincoln are studying the nuances of the gut microbiome. The hope is that an improved understanding of the gut microbiome will help reduce the prevalence of heart disease, diabetes, and inflammatory disorders.

About Fermented Foods

Fermented foods are considered to be the original version of processed food. Fermentation allows for preservation to keep foods nutritious and tasty. Fermented foods have soared in popularity over the recent years as the general public became more interested in health food. Scientists continue to learn more about the important functions of microorganisms for digestion and overall health.

Aside from yogurt, examples of fermented foods and drinks include wine, beer, cheese, salami, fermented pickles, coffee, bread, and chocolate. These items are altered by helpful bacteria, fungi, and yeasts. These foods aresafe to consume for extended periods of time after the alteration. In many instances, fermentation makes the food that much more healthy and flavorful to boot.

About the Research

The research effort is being spearheaded by Robert Hutkins, an accomplished food science researcher. Maria Marco of the University of California is also leading the study. They are working in tandem with an international crew of scientists to determine if eating certain fermented foods like yogurt increases the number ofhelpful microorganisms.

Prior studies have proved that foods like yogurt, miso, and sauerkraut are tied to a reduced rate of diabetes, heart disease, gastrointestinal disorders and other health problems. Hutkins and a dozen other researchers are reviewing this data. He states that the data showsnumerous health benefits to consuming fermented foods like yogurt. He recommends that fermented foods should be included in all diets.

Hutkins' Background

Hutkins is affiliated with the Nebraska Food for Health Center. This group was established last year to study how gut microbes ward off disease and boost human health. It's food, animal and plant scientists work closely with medical experts to identify and develop foods that boost the human microbiome as well as the micro-organisms that reside in the gut. These scientists arefocused on developing foods that boost the body's immune system and metabolic processes.

About Microorganisms

Microorganisms within the gut are fed by the foods one consumes. Therefore it should come as no surprise that diet is an important factor that determines the functionality of the gut microbiome. This is an excellent opportunity to marry agriculture and medicine to alter how we think about warding off disease and treating disease. The hope is that improved knowledge of the main properties of fermentation methods will provide insights in terms of health benefits. However, at the current moment, only yogurt has been identified as a provider ofspecific health benefits. European health authorities made this recognition.

Hutkins' Findings

Hutkins and fellow researchers from the Netherlands, Canada, the United States, Ireland and France have encouraging findings following a thorough review of the latest research into fermented foods. Thegroup determined the increased interest in the impact of microbiomes on health justifies additional research along with clinical trials to study the functions of micro-organisms that reach the gastrointestinal tract via beverages and food.

Some of the studies within Hutkins' group show that yogurt consumption is tied to a decreased rates of diabetes. Additional research determined that beneficial relationships exist between yogurt and digestion, blood pressure, osteoporosis, and cholesterol. One particular study determined those who consume yogurt on a daily basis were less irritable.

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A Yogurt a Day May Keep Disorders at Bay - Anti Aging News

Peter Baranoff, Richard Gold and Carmel Baranoff.

Promise Rejuvenation Center at The Villages held a ribbon cutting and reception to celebrate the opening of its first center at Palm Ridge Plaza. The center provides a variety of customized anti-aging, weight loss and integrative medicine therapy solutions for patients. Dr. Lena Edwards, the chief medical officer, is a board certified Integrative Medicine and Anti-Aging Specialist.

Peter Baranoff, chairman and CEO of Promise Healthcare, remembered being here in 2011 to cut the ribbon for Promise Hospital.

At the hospital we are with people sometimes during their darkest hours of need, said Baranoff. The rejuvenation center will help people live life to the fullest. People will come to us proactively instead of reactively.

Richard Gold and Carmel and Peter Baranoff.

President of Promise Healthcare Richard Gold said that in 30 years of working with physicians, he has never met a doctor as committed and caring as Dr. Edwards.

With this center we are changing sick care to well care, said Gold. We want to help people live longer healthier lives full of vitality, realizing your golden years are in front of you not behind you.

Gold said that The Villages was the logical place for their first center because of the population here that wants to stay active.

We are the first rejuvenation center in the area, said Gold. There are wellness centers here, but we are the first rejuvenation center.

Promise Rejuvenation Center offers a wide variety of services. Dr. Edwards said that two of the main areas she treats people for are hormone imbalances and nutritional deficiencies.

To find out more about the center call (352) 430-3397.

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Promise Rejuvenation Center cuts ribbon at Palm Ridge Plaza in The Villages - Villages-News

It is now possible to print 3-D organs. In fact, ovary structures can be printed to replicate the design of real ovaries. A study conducted at the Northwestern University Feinberg School of Medicine and McCormick School of Engineering determined these 3-D printed ovaries can even produce offspring. The results of the study were published last week in Nature Communications.

How 3-D Printed Ovaries Produce Offspring

A female mouse's ovary can be replaced witha bioprosthetic ovary. The mouse is then able to ovulate and even give birth to pups. Mother miceare also able to nurse their young. The bioprosthetic ovaries are built with 3-D printed scaffolds that hold immature eggs. These ovaries have increased hormone production and restored fertility.

Why the Study is Important

The research is proof that bioprosthetic ovaries have durable functionality across the long haul. There is no longer a need to use cadavers to build organ structures and restore health tissue. This is the breakthrough in regenerative medicine scientists have long hoped for.

Why the Research is Unique

This research is distinct from that conducted by other labs as the design of the scaffold and material (ink) is highly nuanced. The material is made of gelatin, a biological hydrogel created with collagen that is safe for use in humans. The research group knew the scaffold would have to be comprised of organic materials solid enough to be handled in surgery and porous enough to interact with body tissues. They used a gelatin that is self-supporting and capable of building several layers.

No other scientists have printed such gelatin with this level of self-support. This support makes it possible for the ovarian follicles and cells around an immature egg cell tosurvive in the ovary. In a nutshell, this is the first study to show scaffold architecture makes a meaningful difference in the survival of follicles. This would not be possible without a 3-D printer.

What the Study Means for Humans

The scientists' primary objective for creating bioprosthetic ovaries was the restoration of hormone and fertility in women who have endured cancer treatments and now face a heightened risk of infertility. Some young cancer patients' ovaries do not function at a high level and the use of hormone replacement therapy is necessary to spur puberty.

The scaffold used in the study serves to recapitulate the manner in which the ovary functions. It could serve this purpose from the age of puberty, into adulthood, menopause and beyond. Furthermore, the generation of 3-D printed implants to substitute for soft tissue will likely impact future work concerning soft tissue regenerative medicine.

A Look at how 3-D Printing Works

Think of the 3-D printing of an ovary structure as a connecting of a child's Lincoln Logs. These logs at positioned at right angles to build structures. The distance between the logs determines whether the building has doors, windows and so on. 3-D printing is similar except it is performed with depositing filaments. The distance between filaments and advancing angle between the layers can be controlled with ease. The result is the generation of highly precise pore geometries and sizes. Such 3-D printed structures are referred to as scaffolds like those used in the repair/construction of buildings.

Scaffolding supports the materials necessary to repair the structure until it is eventually removed. The remaining structure is self-sustaining without the assistance of the scaffold. 3-D printed scaffolds are implanted into the woman and its pores optimize how the immature eggs are positioned within the scaffold. This support ensures the survival of the immature egg cells andthe cells necessary for hormone production.

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3-D Printed Ovaries Restore Fertility - Anti Aging News

BOCA RATON, FL--(Marketwired - May 16, 2017) - The American Academy of Anti-Aging Medicine will be launching its new podcast, Redefining Medicine, today. Tune in Tuesdays will host weekly sessions with key players in the field of functional and integrative medicine. The podcast will capture and spotlight the personal lives of healthcare professionals and practitioners, allowing listeners to view and hear the more intimate aspects of practicing medicine.

The first three episodes feature Dr. Andrew Heyman, Dr. Pamela W. Smith, and David Asprey, all of whom showcase the benefits of preventive medicine, and discuss the trajectories that led them to their current practices. Later episodes feature physicians who initially worked in the army, emergency medicine, and an array of other disciplines; yet the consistent theme lies in the ultimate decision to seek out and practice integrative healthcare.

These discussions reveal the varied backgrounds and histories of medical professionals, while displaying a more personal and intimate perspective.

The podcast episodes are also available on iTunes, free of charge.

About the American Academy of Anti-Aging Medicine

The American Academy of Anti-Aging Medicine (A4M) is the world's largest non-profit society of physicians and scientists committed to research that helps optimize the human aging process, along with the advancement of techniques and technologies that detect, prevent, and treat aging-related diseases.

A4M offers exclusive membership to all medical professionals, with the potential to access over two-decades of established medical expertise. We are dedicated to educating physicians, scientists, and all healthcare professionals, and are proud to be in our 24th year of providing first-class continuing education conferences on anti-aging, regenerative, and functional medicine.

To learn more, register for any event, enroll in any training program, or exhibit at an A4M Conference, please contact the office of the American Academy of Anti-Aging medicine at:

Toll-Free - US Only: (888) 997-0112

International: (561) 997-0112

Email: rel="nofollow">info@a4m.com

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The American Academy of Anti-Aging Medicine Introduces New Podcast: Redefining Medicine - Markets Insider

Posted on May 16, 2017, 6 a.m. in Cardio-Vascular Respiratory

Research findings confirm that a respiratory infection can trigger a heart attack, increasing the risk by 17 times in the 7 days following the infection.

Researchers at the University of Sydney have determined the risk of suffering a heart attack is 17 times higher in the week after a respiratory infection. The study took place at Royal North Shore Hospital. The findings were recently published in the Internal Medicine Journal. It is the first study to show a link between respiratory infections like bronchitis, influenza and pneumonia and a heightened risk of heart attack in individuals confirmed through coronary angiography. Coronary angiography is an X-Ray that pinpoints artery blockages in the heart.

Why the Findings Matter

The findings are of significance as they confirm that respiratory infections can serve as a trigger for heart attacks. The study's data showed that a heightened risk for heart attack does not solely occur at the beginning of the respiratory symptoms. The risk peaks in the first week and slowly decreases. However, it is elevated for a full month.

About the Study

The study involved nearly 600 consecutive patients who suffered a heart attack as a result of a coronary artery blockage. They provided information on recent and common occurrences of respiratory infection symptoms. Just over 20 percent of the patients reported respiratory infection symptoms within the first month of their heart attack. Exactly 17 percent of the patients reported respiratory infection symptoms within a week of the heart attack.

Each subject was questioned about his activities prior to the onset of the heart attack. These interviews included questions about whether they endured recent flu-like sickness with a sore throat and/or fever. If a subject reported a cough, sore throat, sinus pain, fever or flu-like symptoms, he was considered to be affected. The same is true of those who reported a diagnosis of bronchitis or pneumonia.

Another analysis was performed amongst those with symptoms limited to the upper respiratory tract. These symptoms included sinusitis, rhinitis, pharyngitis and the common cold. Subjects who reported fairly mild infection symptoms of the upper respiratory tract endured less risk. However, this risk was still boosted 13-fold.

Though upper respiratory infections are not as severe, they are more common than the symptoms of lower respiratory tract infections. The research group desired to understand their relationship to the risk of heart attacks. This information is especially important during the winter. Heart attacks tend to occur at higher rates in the winter months in countries around the world. Part of the reason for this increase is due to an elevation of respiratory infections during the colder months. Medical professionals far and wideadvise people to take precautions to minimize exposure to infection, whether it is a pneumonia vaccine, flu vaccine or other measures.

Why Respiratory Infections Trigger Heart Attacks

Though no one is completely certain why respiratory infections cause heart attacks, researchers point to the fact that blood clots occur at a higher frequency when one has a respiratory infection. There is also an increased tendency for other alterations in blood flow, inflammation, and toxins harming blood vessels. However, the odds of a single episode of a respiratory infection causing a heart attack are low. Yet it is still possible for such an infection to cause a coronary event.

Everyone should consider preventative strategies and take note of the symptoms that are an indication of a heart attack. As time progresses, medical professionals will eventually pinpoint effective treatment strategies to minimize the risk of heart attacks. This is especially important for those who face a higher susceptibility to heart attacks.

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Heart Attack Risk Raised by Respiratory Infections - Anti Aging News

BOCA RATON, FL--(Marketwired - May 16, 2017) - The American Academy of Anti-Aging Medicine will be launching its new podcast, Redefining Medicine, today. Tune in Tuesdays will host weekly sessions with key players in the field of functional and integrative medicine. The podcast will capture and spotlight the personal lives of healthcare professionals and practitioners, allowing listeners to view and hear the more intimate aspects of practicing medicine.

The first three episodes feature Dr. Andrew Heyman, Dr. Pamela W. Smith, and David Asprey, all of whom showcase the benefits of preventive medicine, and discuss the trajectories that led them to their current practices. Later episodes feature physicians who initially worked in the army, emergency medicine, and an array of other disciplines; yet the consistent theme lies in the ultimate decision to seek out and practice integrative healthcare.

These discussions reveal the varied backgrounds and histories of medical professionals, while displaying a more personal and intimate perspective.

The podcast episodes are also available on iTunes, free of charge.

About the American Academy of Anti-Aging Medicine

The American Academy of Anti-Aging Medicine (A4M) is the world's largest non-profit society of physicians and scientists committed to research that helps optimize the human aging process, along with the advancement of techniques and technologies that detect, prevent, and treat aging-related diseases.

A4M offers exclusive membership to all medical professionals, with the potential to access over two-decades of established medical expertise. We are dedicated to educating physicians, scientists, and all healthcare professionals, and are proud to be in our 24th year of providing first-class continuing education conferences on anti-aging, regenerative, and functional medicine.

To learn more, register for any event, enroll in any training program, or exhibit at an A4M Conference, please contact the office of the American Academy of Anti-Aging medicine at:

Toll-Free - US Only: (888) 997-0112

International: (561) 997-0112

Email: info@a4m.com

Continued here:
The American Academy of Anti-Aging Medicine Introduces New Podcast: Redefining Medicine - Marketwired (press release)

Actor Antonio Sabato, Jr., was suffering from depression, mood swings, and just feeling a tremendous loss of energy until he discovered hormone therapy that he says changed his life around.

Sabato, a staunch Republican who recently announced that he is running for Congress, was a vocal supporter of President Donald Trump during the 2016 campaign. The actor has long been interested in politics and public policy, but he tells Newsmax Health his health woes prevented him from performing his best.

The Italian-born heart throb best known for his role as Jagger Cates in the soap opera General Hospital and his work as a Calvin Klein model, discovered that his debilitating symptoms stemmed from hormone depletion, a condition that strikes one in four men over the age of 30.

The symptoms may also include low sex drive, sleep disturbances, depressed mood, lethargy, and diminished physical performance.

For me, I couldnt understand why I was feeling so low, Sabato tells Newsmax Health. Ive always worked out to keep myself in top shape for my demanding roles in movies and on television and I just wasnt bouncing back the way I used to. I suffered from terrible mood swings and insomnia. The doctors I went to wanted to give me pills, which I took at the beginning but then I felt trapped.

I didnt want to take sleeping pills and antidepressants. I just want to feel like myself again.

Rather than throwing in the towel and chalking up his lethargy to aging, Sabato was determined to find an effective treatment for his condition.

After a great deal of searching he met Dr. Christopher Asandra, who is board-certified by the American Board of Anti-Aging and Regenerative Medicine and a leading anti-aging expert.

His program includes custom-tailored replacement therapy for both men and women to replace hormone levels diminished by the aging process, menopause and andropause, stress, diabetes, obesity, certain medications, and alcohol use.

By careful testing and evaluating each patients blood work, I prescribe a formula that restores optimum hormone levels which soon translates into optimum health, Asandra tells Newsmax Health.

After following Asandras protocol Sabato, 45, says he feels decades younger.

I should have started his program in my 30s, he laughs. I have amazing energy and vitality and my mood swings are gone. I sleep like a baby and as an added benefit the brain fog disappeared and I have incredible mental clarity which is an asset when I need to memorize scripts.

The therapy consists of inserting two tic-tac sized time-release pellets containing bio-identical testosterone hormones that slowly regulate the body over a 5-6 month period. Sabato also uses Asandras growth hormone called Sermorelin, a sequence of 29 vital amino acids taken daily at night to stimulate growth hormone production.

This treatment helps improve bone density, strengthen the cardiovascular system, increase muscle mass and improve cognitive and memory function, says Asandra.

But patients must also do their part, the expert insists.

I can jump start their systems but they have to change their lifestyles to get off the couch, start exercising and eating right, he says.Its like the old expression, I can lead the horse to water but I cant make him drink!

Sabato changed his diet to include 80 percent vegetables, fish, and chicken.

I eat red meat once in a while but I usually stick to a huge salad with fish, he says. I eat no dairy, eggs or bread.

Sabato, a self-professed workout enthusiast works out strenuously six days a week.

I do resistance training, cardio and Jiu Jitsu, a form of martial arts, he says. Thanks to the hormone therapy I have far more energy than ever before.

Asandra says that the secret to successful anti-aging therapy is to be judicious in replacing lost hormones.

Some of my patients only need to have hormone therapy for a year to get back their energy, get off the couch and stay motivated to keep their bodies and minds healthy, he says. We customize all our therapies to ensure optimum levels which are carefully monitored by regular blood tests.

My patients say it is life changing not only for them, but also for the people around them, he says, noting his treatment is generally not covered by insurance. When you are on an even keel mentally, in top shape physically and can enjoy intimacy once again, a price tag similar to buying a Starbuck coffee daily is so worth it!

Asandra says it is important to find the right doctor who will listen to your needs and treat the cause of your symptoms rather than use a Band-Aid approach.

2017 NewsmaxHealth. All rights reserved.

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Actor Antonio Sabato Touting Hormone Therapy - Newsmax

BROWNSVILLE, Texas, May 16, 2017 /PRNewswire/ Dr. Manjula Raguthu is recognized by Continental Whos Who as a Top Doctor of 2017. Dr. Raguthu is a Physician at Medwin Family Medicine & Rehabilitation.

According to their website, Medwin Family Medicine & Rehabilitation, established in 2002, is a healthcare facility that serves patients of all ages and is aimed at delivering high quality and comprehensive health care services at two locations. The physicians at Medwin Family Medicine & Rehabilitation are dedicated to providing patients with utmost care with convenient locations and flexible office hours.

Specializing in internal and family medicine, Dr. Raguthu possesses over twenty years in the medical field. Her areas of expertise include the following: acute care, anti-aging, pediatrics, obstetrics and gynecology, pain management as well as sports medicine and injury. Her role at Medwin consists of overseeing the primary care clinic and assigning clinical duties to the staff, and she has also worked in emergency medicine. She believes strongly HEALTH IS WEALTH.

Recognized as one of the Best Family Physicians in America by the Consumers Research Council of America for 2009, 2006 and 2004, Dr. Raguthu holds 32nd rank in Family Practice Boards in America. She has received distinctions in the fields of Microbiology and Opthalmology, and an Exemplary Leadership Award in her field in 2001. Additionally, she was awarded the Distinguished Humanitarian Award, and was named the Professional of the Year in 2015 and 2016 by Elite American Physician, as well as many other honors throughout the course of her career.

To further her professional development, Raguthu is member of the American Academy of Family Physicians, American Medical Association, American Association of Physicians of Indian Origin, Texas Academy of Family Physicians and American Anti-Aging Academy. She is also involved with the American Anti-Aging and Regenerative Medicine Society.

Heavily educated in her line of work, Dr. Raguthu earned her Postgraduate Diploma in Obstetrics and Gynecology in addition to a Bachelor of Medicine and Bachelor of Surgery from Guntur Medical College in 1990, and completed her residency at St. Vincents Medical Center in New York. In 2008, she was Re-Certified in Family Practice and holds an Advanced Trauma Life Support Certification, Medical Office Management Certification and is a Certified Medical Coder and Certified Compliance Officer.

Outside of work, Dr. Raguthu enjoys photography, chess, reading, and playing badminton.

For more information, please visit http://www.medwinfamily.com

Contact: Katherine Green, 516-825-5634, pr@continentalwhoswho.com

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Dr. Manjula Raguthu is recognized by Continental Who's Who - MilTech

Boca Raton, Florida (PRWEB) May 15, 2017

White Lotus, a company known for its line of holistic eastern anti-aging regime, announced its products are now for sale on NPIBeauty.com, a popular website for beauty and wellness brands.

The company was founded in 2007 in Brisbane, Australia as an offshoot of Golden Dragon TCM. Anthony and Kamila Kingston founded the company after studying acupuncture and Chinese medicine, having traveled all over the world in their work and studies. Ultimately they returned to Brisbane with knowledge of this ancient field of medicine and cosmetics. These principles are present in all White Lotus products, which are now available on NPIBeauty.com.

We are excited to be able to provide our products through yet another digital platform that reaches customers all over North America, said Anthony Kingston. This new sales partnership with NPIBeauty.com is yet another step toward broadening our market reach and being able to help more people benefit from eastern medicine and acupuncture.

While other companies have some level of focus on Chinese medicine and acupuncture for anti-aging purposes, these companies do not have the same standards of testing and research for their products as White Lotus. All of White Lotuss products carefully address important issues such as aging spots, stretch marks, scars, wrinkles, skin conditions, hair loss, chronic pains, and more in a safe, effective manner.

The companys jade products have already found a level of success in the United States. The jade roller, for example, improves lymphatic drainage, skin smoothness, and microcirculation. The White Lotus clinics in Australia have become known for their jade facials. Therefore, this roller allows international customers to experience some of that clinic experience from thousands of miles away, from the comfort of their homes.

We are eager to continue expanding our brands reach and to help people on a wider scale to achieve a fresh, youthful appearance with some natural, time-tested techniques, said Kingston.

For more information about White Lotus and its products, visit http://www.whitelotusantiaging.com.

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White Lotus Products Arrive on NPIBeauty.com - PR Web (press release)

Miami-based plastic surgeon Dr. Alex de Souza is partnering with Dr. Robert Rey, a Beverly Hills plastic surgeon and the star of reality TV show Dr. 90210, to start a practice here in Orlando.

The duo is starting small, performing their procedures at the outpatient surgery facility Endo-Surgical Center of Florida on North Dean Road. They hope to eventually establish a boutique practice here called World Plastic Surgery Center.

De Souza and Rey, who are part of a small community of Brazilian plastic surgeons in the United States, said starting a practice in Orlando made sense, because its a major tourist hub with a busy airport, and because compared to Miami and Beverly Hills, its more affordable.

We looked at different places, said Rey in an interview peppered with inspirational advice including Lift your head, Choose to be happy, and The enemy is the fridge.

Orlando is the most-visited city on earth. Its very heterogenous and is a centralized location, he said.

Brazilian tourists make up one of the top five international groups in Orlando, but de Souza said that wasnt the main deciding factor in choosing the area.

Dr. Harinath Sheela, a gastroenterologist and one of the partners at Endo-Surgical Center, said one of the reasons de Souza and Rey chose to work from his surgery center was because its close to the airport with access to state roads 408 and 417. An independent outpatient surgery center, Endo-Surgical was established here six years ago.

Promise Healthcare, a national hospital company, is opening its first Promise Rejuvenation Center at The Villages, providing anti-aging, weight loss and integrative medicine therapy. Dr. Lena Edwards, board certified in integrative medicine, is the clinics chief medical officer.

Fishman and Sheridan EyeCare Specialists are establishing new offices in Clermont and Eustis, set to open in 2018.

Bostwick Laboratories, a specialty anatomic pathology laboratory with locations in Orlando, New York and Virginia, has been acquired by Poplar Healthcare, a Memphis-based laboratory services company.

TrueHealth, a private nonprofit community health center in Central Florida, held its inaugural fundraising gala May 6, raising nearly $80,000 through contributions and ticket sales.

Embry-Riddle Aeronautical Universitys Daytona Beach campus is started an undergraduate program in aerospace physiology in collaboration with Florida Hospital and its campuses in Volusia and Flagler counties.

Abel Biri is the new CEO of Florida Hospital Waterman, replacing David Ottati, who recently became president and CEO of Florida Hospitals Central Florida Division-North Region.

Brea Weiss, a career-development professional, is the new board chair for Florida Hospital for Children.

David Overfield is Orange County health departments new Interim Assistant Health Officer. Hes replacing Lesli Ahonkhai, whos retiring in June.

Jennifer Knight, a pre-operative nurse at Poinciana Medical Center, received the DAISY Award for Extraordinary Nurses for providing exceptional patient care.

nmiller@orlandosentinel.com or 407-420-5158; Twitter, @naseemmiller

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'Dr. 90210' star accepting patients in Orlando - Orlando Sentinel

Despite their best efforts, no scientist has ever come close to stopping humans from aging. Even anti-aging creams can't stop Old Father Time.

But new research from Brigham Young University reveals you may be able to slow one type of aging -- the kind that happens inside your cells. As long as you're willing to sweat.

"Just because you're 40, doesn't mean you're 40 years old biologically," Tucker said. "We all know people that seem younger than their actual age. The more physically active we are, the less biological aging takes place in our bodies."

The study, published in the medical journal Preventive Medicine, finds that people who have consistently high levels of physical activity have significantly longer telomeres than those who have sedentary lifestyles, as well as those who are moderately active.

Telomeres are the protein endcaps of our chromosomes. They're like our biological clock and they're extremely correlated with age; each time a cell replicates, we lose a tiny bit of the endcaps. Therefore, the older we get, the shorter our telomeres.

Exercise science professor Larry Tucker found adults with high physical activity levels have telomeres with a biological aging advantage of nine years over those who are sedentary, and a seven-year advantage compared to those who are moderately active. To be highly active, women had to engage in 30 minutes of jogging per day (40 minutes for men), five days a week.

"If you want to see a real difference in slowing your biological aging, it appears that a little exercise won't cut it," Tucker said. "You have to work out regularly at high levels."

Tucker analyzed data from 5,823 adults who participated in the CDC's National Health and Nutrition Examination Survey, one of the few indexes that includes telomere length values for study subjects. The index also includes data for 62 activities participants might have engaged in over a 30-day window, which Tucker analyzed to calculate levels of physical activity.

His study found the shortest telomeres came from sedentary people -- they had 140 base pairs of DNA less at the end of their telomeres than highly active folks. Surprisingly, he also found there was no significant difference in telomere length between those with low or moderate physical activity and the sedentary people.

Although the exact mechanism for how exercise preserves telomeres is unknown, Tucker said it may be tied to inflammation and oxidative stress. Previous studies have shown telomere length is closely related to those two factors and it is known that exercise can suppress inflammation and oxidative stress over time.

"We know that regular physical activity helps to reduce mortality and prolong life, and now we know part of that advantage may be due to the preservation of telomeres," Tucker said.

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High levels of exercise linked to nine years of less aging at the ... - Science Daily

Updated | Its not quite eternal youth but scientists have discovered how humans can slow down the aging process and shave almost a decade off their biological agevigorous exercise. In a study of more than 5,000 adults in the U.S., a researcher found those who exercise regularly are younger on a cellular level than those who lead sedentary or moderately active lifestyles.

Research published in the journal Preventative Medicine in April considered data on 5,823 people who had participated in the National Health and Nutrition Examination Survey between 1999 and 2002. The participants were asked demographic and lifestyle questions, including how often they exercised.

They also looked at telomere length. Telomeres are protective caps found at the ends of chromosomes that help keep them stablenot unlike how the plastic sheath at the end of shoelaces stops them from fraying. Every time a cell divides, telomeres get shorter. Eventually they become too small to protect the chromosomes and cells get old and dieresulting in aging.

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English women athletes training in Battersea Park, London, 21st September 1937. Regular, vigorous exercise makes people up to nine years younger. Hulton Archive/Getty Images

Shorter telomeres are related to many age-related diseases, including cancer, stroke and cardiovascular disease.

In the study, exercise science professor Larry Tucker from Brigham Young Universitycompared telomere length with levels of physical activity. His findings showed significant differences between those who did regular, vigorous exercise and those who did not.

Just because youre 40, doesnt mean youre 40 years old biologically, he said in a statement. We all know people that seem younger than their actual age. The more physically active we are, the less biological aging takes place in our bodies.

He discovered adults with a high level of physical activity had a biological aging advantage of nine years compared to sedentary adults. When compared with those who did a moderate amount of exercise, the difference for highly active adults was seven years.

A high level of physical activity was constituted as running between 30 and 40 minutes per day, at least five days per week.

Overall, physical activity was significantly and meaningfully associated with telomere length in U.S. men and women, he wrote. Evidently, adults who participate in high levels of physical activity tend to have longer telomeres, accounting for years of reduced cellular aging compared to their more sedentary counterparts.

He said exactly why exercise appears to preserve telomere length is not known, but added it could be linked with inflammation and oxidative stressexercise is known to suppress inflammation and stress over time.

If you want to see a real difference in slowing your biological aging, it appears that a little exercise wont cut it. You have to work out regularly at high levels, he said. We know that regular physical activity helps to reduce mortality and prolong life, and now we know part of that advantage may be due to the preservation of telomeres.

This article has been updated with the name of the university where Larry Tucker works.

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Exercise Has Anti-aging Benefits and Makes You Years Younger on a Cellular Level - Newsweek

The movement to look -- and feel -- younger continues to be big business, with an endless supply of customers. According to Transparency Market Research, the global anti-aging industry will be worth nearly $200 billion by 2019. The reasons for that growth are clear: All adults have insecurities surrounding aging and thus are potential customers.

Related: 5 Ways New Companies Are Capturing the Growing Senior Market

What truly makes the anti-aging segment exciting is how much room it holds for growth. The reason is that for anti-aging technologies, unlike other categories, the gap between research and application is wide. Anti-aging solutions remain the focus of intensive research, and those eventual findings will create new potential.

Meanwhile, because no universal standard currently exists for these solutions, even the idea of what an anti-aging product is, is up for grabs. But, essentially, what industry observers can agree on is that anti-aging offers savvy entrepreneurs major advantages in both the health and beauty markets.

However, there is a caveat: Entrepreneurs who jump blindly into the anti-aging industry will surely gain a few wrinkles along the way. As in any industry, success takes specialized knowledge, skill and hard work. Here are a few ways to start down the path to creating a successful anti-aging business:

In any business, extra education is a competitive advantage. Special knowledge makes it harder for the competition to enter the market; and it helps entrepreneurs already there to stay on top, because knowing about the latest and best science is a vital part of success in the anti-aging market.

Another tip for success is knowing where the rewards are: I set up the Brighten Award for Entrepreneurial Gerontology at the University of Southern California Leonard Davis School of Gerontology. It honors business students creating products and services aimed at older audiences. Hopefully, this opportunity will spark continued education in the gerontology field by academics and entrepreneurs alike.

Entrepreneurs in this field should also look for lectures and conferences and chances to enhance their education in the anti-aging field. The American Academy of Anti-Aging Medicine offers a number of fellowships, certifications, symposiums and graduate programs for those wanting to expand their anti-aging knowledge base. Anti-aging technology changes so often that continuously furthering your education is a necessity.

Related: 3 Ways to Encourage Your Employees to Keep Learning

While members of the younger generations will have some interest in your anti-aging product, baby boomers are your best investment source. People over 50 control 70 percent of the disposable income in the United States and are estimated to spend $52 billion globally each year.

It's no wonder then that the marketing of anti-aging products is on the rise -- so much so that the European modeling agency MOT Models has created a new division called RETRO -- featuring mature models -- tto help more companies attract customers over age 50 and bring in new streams of revenue.

Entrepreneurs in the anti-aging field need to find a need that their product can address, then hit it hard. For instance, anti-aging skin care is a robust market expected to eclipse $11 billion by 2018 in the United States alone. So, narrow in on a specific industry to position your company to benefit financially and become a market trendsetter.

Like anything that touches on medical needs, the anti-aging industry comes with a slew of regulations. Because many consumers are still skeptical about anti-aging products, it's in everyone's best interest that his market not be flooded with ineffective or unsafe products.

Each year, the Food and Drug Administration sends warning letters to companies marketing as cosmetics anti-aging products that are really drugs. The FDA defines a cosmetic as something designed for "cleansing, beautifying and promoting attractiveness or altering appearance," while a drug is something that will "affect the structure or any function of the body."

Understanding the distinction is key. That's why it's important to go through all the necessarary documentation and legislation at the state and federal levels to ensure compliance. This will prevent potential regulatory headaches and provide insight on where the anti-aging industry is headed. When new regulations pop up, opportunities for expansion may not be far behind.

Related: 5 Ways to Effectively Market to Baby Boomers

In sum, the anti-aging market is booming -- thanks to the boomers. For entrepreneurs looking for the next big thing, that next big thing may involve jolting the over-50 crowd with a shot of vitality. So, stay educated, focused and compliant, and your anti-aging product will enjoy a long and healthy shelf life.

Kevin Xu is the CEO of MEBO International, a California- and Beijing-based intellectual-property management company specializing in applied health systems. He also leads Skingenix, which specializes in skin organ regeneration and the resear...

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Why Anti-Aging Products Are the New Startup Frontier - Entrepreneur