Biotechnology is an interdisciplinary field that uses a combination of biology and technology to design and produce new molecules, plants, animals and microorganisms with improved characteristics. Biotechnology offers seemingly unlimited opportunities to combine genes from related or unrelated species to produce useful organisms with desirable properties that were not previously found in nature.
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Biotechnology may be thought of as a collection of technologies using animal and/or plant cells, biological molecules, molecular biology processes and genetic engineering for applications in medicine, agriculture and the pharmaceutical industry. The technologies include the use of recombinant DNA for gene cloning and gene transfers between organisms; culture of plant and animal cells and tissues; fusion of animal cells or plant protoplast; the regeneration of whole plants from single cells and the large-scale fermentation processes that use some of these novel organisms for the production of pharmaceuticals, diagnostic tests for diseases, feed additives, enzymes and hormones.
Examples of successful biotechnology include the development of crop plants that are resistant to herbicides or insects, the production of human growth hormone and insulin by genetically engineered bacteria and the development of unique vaccines.
The biotechnology program is offered through both the College of Agriculture, Food Systems, and Natural Resources and the College of Science and Mathematics and leads to a Bachelor of Science degree.
The recommended course of study includes both the education in science and mathematics, as well as introduction to the special skills that are needed to enter the rapidly expanding and changing field of biotechnology. In addition to the required courses, students may select from a variety of specialized elective science courses to help develop a particular area of interest. Students majoring in biotechnology are required to perform a research project in the laboratory of a faculty advisor. The results of the research project are incorporated into a senior thesis and presented at the Biotechnology Seminar.
Biotechnology students must maintain at least a 2.5 overall grade point average (GPA) after 60 credits in order to remain in the program.
A faculty advisor is assigned to each student to assist in scheduling, registration and career development. Faculty in each of the cooperating life-science departments have been identified to serve as academic and research advisors for students who select the biotechnology major. The faculty advisor and the director of the biotechnology program regularly review the progress of each student.
The faculty who advise, teach and serve as research mentors for the biotechnology program are spread among several academic departments in the College of Agriculture, Food Systems, and Natural Resources, the College of Science and Mathematics and the College of Health Professions. The departments include plant sciences; biological sciences, biology, botany and zoology; chemistry, biochemistry and molecular biology; animal and range sciences; plant pathology; veterinary and microbiological sciences; and pharmaceutical sciences. Several scientists at the NDSU Center for Nanoscale Science and Engineering and at the on-campus USDA facilities also serve as research mentors.
Laboratory facilities and specialized equipment are used for instruction and research. These include animal and plant tissue culture facilities, small animal housing, electron and confocal microscopes, automated DNA sequencing equipment, equipment for performing microarray experiments, and NDSU Core Labs. The Core Labs are shared cutting-edge research facilities and include the Advanced Imaging and Microscopy Core, Core Biology Facility, Core Synthesis and Analytical Services and the Electron Microscopy Core Laboratory, among many other state-of-the-art facilities and equipment.
Biotechnology continues to rapidly develop into new research areas. Surveys indicate there will be a continuing high demand for well-educated personnel. Job opportunities are found in life science departments in colleges and universities; private and government research institutes; food production, pharmaceutical and agri-chemical industries; and in the biotechnology industries. Graduates of this program have the educational background and laboratory experience to take advantage of any of these job opportunities. Graduates of the biotechnology program are now successful and productive scientists at pharmaceutical, agri-chemical and biotechnology companies, and at government and private research institutions throughout the country.
The majority (approximately 60 percent) of graduates from the biotechnology program choose to continue their education in graduate or professional schools. Graduates of the biotechnology program have earned masters and doctoral degrees in many diverse areas, including cellular and molecular biology, biology, microbiology, plant sciences, animal physiology, cancer biology and virology at many of the most respected universities in the United States. Graduates of our program are now established and productive professors, physicians and veterinarians.
Students entering the biotechnology program should have a strong background in mathematics, including trigonometry, biology, chemistry, preferably physics, writing and computer courses. A composite ACT score of 26 or higher is recommended.
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This sample curriculum is not intended to serve as a curriculum guide for current students, but rather an example of course offerings for prospective students. For the curriculum requirements in effect at the time of entrance into a program, consult with an academic advisor or with the Office of Registration and Records.
Van Es Hall Lab 160
Van Es Hall is located on the west side of campus on Centennial Boulevard (Campus Map)
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Biotechnology - Academic Majors (NDSU)
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- Comparing the fermentation performance of Escherichia coli KO11, Saccharomyces cerevisiae 424A(LNH-ST) and Zymomonas mobilis AX101 for cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: May 28th, 2010]
- Enzymatic digestibility and ethanol fermentability of AFEX-treated starch-rich lignocellulosics such as corn silage and whole corn plant [Last Updated On: August 17th, 2024] [Originally Added On: June 10th, 2010]
- Improved xylose and arabinose utilization by an industrial recombinant Saccharomyces cerevisiae strain using evolutionary engineering [Last Updated On: August 17th, 2024] [Originally Added On: June 16th, 2010]
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- Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding [Last Updated On: August 17th, 2024] [Originally Added On: August 3rd, 2010]
- Practical screening of purified cellobiohydrolases and endoglucanases with alpha-cellulose and specification of hydrodynamics [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Techno-economic evaluation of stillage treatment with anaerobic digestion in a softwood-to-ethanol process [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: October 11th, 2010]
- Rapid optimization of enzyme mixtures for deconstruction of diverse pretreatment/biomass feedstock combinations [Last Updated On: August 17th, 2024] [Originally Added On: October 13th, 2010]
- Automated saccharification assay for determination of digestibility in plant materials [Last Updated On: August 17th, 2024] [Originally Added On: November 7th, 2010]
- Biodetoxification of toxins generated from lignocellulose pretreatment using a newly isolated fungus, Amorphotheca resinae ZN1, and the consequent ethanol fermentation [Last Updated On: August 17th, 2024] [Originally Added On: November 28th, 2010]
- Lignin monomer composition affects Arabidopsis cell-wall degradability after liquid hot water pretreatment [Last Updated On: August 17th, 2024] [Originally Added On: December 11th, 2010]
- Thermostable endoglucanases in the liquefaction of hydrothermally pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: February 6th, 2011]
- Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates [Last Updated On: August 17th, 2024] [Originally Added On: February 14th, 2011]
- Arsenal of plant cell wall degrading enzymes reflects host preference among plant pathogenic fungi [Last Updated On: August 17th, 2024] [Originally Added On: February 16th, 2011]
- Hemicellulases and auxiliary enzymes for improved conversion of lignocellulosic biomass to monosaccharides [Last Updated On: August 17th, 2024] [Originally Added On: February 22nd, 2011]
- Two-step synthesis of fatty acid ethyl ester from soybean oil catalyzed by Yarrowia lipolytica lipase [Last Updated On: August 17th, 2024] [Originally Added On: March 6th, 2011]
- Topochemical distribution of lignin and hydroxycinnamic acids in sugar-cane cell walls and its correlation with the enzymatic hydrolysis of polysaccharides [Last Updated On: August 17th, 2024] [Originally Added On: March 17th, 2011]
- Direct ethanol production from cellulosic materials using a diploid strain of Saccharomyces cerevisiae with optimized cellulase expression [Last Updated On: August 17th, 2024] [Originally Added On: April 17th, 2011]
- Isolation of xylose isomerases by sequence- and function-based screening from a soil metagenome library [Last Updated On: August 17th, 2024] [Originally Added On: May 8th, 2011]
- Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Effect of mixing on enzymatic hydrolysis of steam-pretreated spruce: a quantitative analysis of conversion and power consumption [Last Updated On: August 17th, 2024] [Originally Added On: May 15th, 2011]
- Thermostable recombinant xylanases from Nonomuraea flexuosa and Thermoascus aurantiacus show distinct properties in the hydrolysis of xylans and pretreated wheat straw [Last Updated On: August 17th, 2024] [Originally Added On: May 22nd, 2011]
- Investigation of tension wood formation and 2,6-dichlorbenzonitrile application in short rotation coppice willow composition and enzymatic saccharification [Last Updated On: August 17th, 2024] [Originally Added On: May 29th, 2011]
- Aiming the complete utilization of sugar beet pulp through mild acid and hydrothermal pretreatment followed by enzymatic digestion [Last Updated On: August 17th, 2024] [Originally Added On: June 5th, 2011]
- Alkaline peroxide pretreatment of corn stover: effects of biomass, peroxide, and enzyme loading and composition on yields of glucose and xylose [Last Updated On: August 17th, 2024] [Originally Added On: June 12th, 2011]
- In-situ lignocellulosic unlocking mechanism in termite for carbohydrate hydrolysis: critical lignin modification [Last Updated On: August 17th, 2024] [Originally Added On: June 19th, 2011]
- Supplementation with xylanase and beta-xylosidase to reduce xylo-oligomer and xylan inhibition of enzymatic hydrolysis of cellulose and pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: June 26th, 2011]
- Co-hydrolysis of hydrothermal and dilute acid pretreated Populus slurries to support development of a high-throughput pretreatment system [Last Updated On: August 17th, 2024] [Originally Added On: July 17th, 2011]
- Evaluation of preservation methods for improving biogas production and enzymatic conversion yields of annual crops [Last Updated On: August 17th, 2024] [Originally Added On: July 24th, 2011]
- Simultaneous saccharification and co-fermentation of lignocellulosic residues from commercial furfural production and corn kernels using different nutrient media [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
- Increased isobutanol production in Saccharomyces cerevisiae by overexpression of genes in valine metabolism [Last Updated On: August 17th, 2024] [Originally Added On: July 31st, 2011]
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- Functional characterization of cellulases identified from the cow rumen fungus neocallimastix patriciarum W5 by transcriptomic and secretomic analyses [Last Updated On: August 17th, 2024] [Originally Added On: August 21st, 2011]
- Simultaneous utilization of glucose and xylose for lipid production by Trichosporon cutaneum [Last Updated On: August 17th, 2024] [Originally Added On: August 28th, 2011]
- Conversion of deoxynivalenol to 3-acetyldeoxynivalenol in barley derived fuel ethanol co-products with yeast expressing trichothecene 3-O-acetyltransferases [Last Updated On: August 17th, 2024] [Originally Added On: September 4th, 2011]
- Comparative performance of precommercial cellulases hydrolyzing pretreated corn stover [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- Impact of pretreatment and downstream processing technologies on economics and energy use in cellulosic ethanol production [Last Updated On: August 17th, 2024] [Originally Added On: September 11th, 2011]
- A kinetic model for quantitative evaluation of the effect of H2 and osmolarity on hydrogen production by Caldicellulosiruptor saccharolyticus [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- High level secretion of cellobiohydrolases by Saccharomyces cerevisiae [Last Updated On: August 17th, 2024] [Originally Added On: September 18th, 2011]
- How recombinant swollenin from Kluyveromyces lactis affects cellulosic substrates and accelerates their hydrolysis [Last Updated On: August 17th, 2024] [Originally Added On: September 25th, 2011]
- Bio-conversion of paper sludge to biofuel by simultaneous saccharification and fermentation using a cellulase of paper sludge origin and thermotolerant Saccharomyces cerevisiae TJ14 [Last Updated On: August 17th, 2024] [Originally Added On: October 2nd, 2011]
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- Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
- A cellular automaton model of crystalline cellulose hydrolysis by cellulases [Last Updated On: August 17th, 2024] [Originally Added On: October 23rd, 2011]
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