Side Effects of Testosterone Replacement Therapy (TRT)

Posted on November 23, 2017 by Prof Baldwin

As with any medical intervention, the benefits of Low T therapy must be weighed against the potential risk of adverse reactions the side effects of testosterone replacement therapy can be a problem if not properly managed by a trained provider.

Just as Paracelsus says, whether testosterone replacement creates a poisonous or beneficial environment is largely dependent upon how the medication is delivered and dosed.

Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy. Paracelsus

Those who abuse testosterone and other androgens may experience significant and even life threatening side effects.

Somewhat similarly, if treatment of Low T is mismanaged or not carefully monitored, patients will experience a higher rate and increased severity of adverse reactions or possibly a complete lack of meaningful results.

For the most part, this discussion will deal with the side effects of testosterone replacement therapy (TRT) in general, but some attention will be given to particular differences in the variety of methods utilized for treatment of Low T.

You can also watch the video below to hear from one of our founding partners, Augie Galindo, PA-C about the side effects of testosterone replacement therapy.

This video is about the Side Effects of TRT. Every medical intervention has potential issues, and treating Low T is no different. Learn about our approach to monitor and maintain safe testosterone levels.

Some side effects seen with TRT are the direct result of the use of exogenous testosterone (testosterone not made naturally in the body).

Pharmaceutical grade testosterone is bio-identical, that is, it is constructed, recognized, and utilized in the same manner as the hormone produced by your body.

Many adverse effects occur only in the presence of higher testosterone levels, and still others are simply the consequences of the bodys normal metabolism of testosterone.

This metabolism, or breakdown of testosterone, occurs in the same manner for both exogenous and endogenous testosterone (naturally produced testosterone), but because of an increased abundance of testosterone this may lead to higher than normal levels of these metabolites.

Normal metabolism of testosterone results in its conversion into two primary metabolites, dihydrotestosterone (DHT) and estradiol (E2, a form of estrogen).

Elevated levels of DHT can cause benign growth of the prostate, increased oiliness of the skin and acne, as well as male pattern balding.

Abnormal increases in estradiol can lead to mood swings, breast tissue changes, and fluid retention that may cause swelling or increases in blood pressure. Furthermore, abnormal estradiol levels have been linked to lower testosterone levels, erectile dysfunction, and a decrease in free testosterone.

According to the 2010 update to Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline, the conversion rate and subsequent ratio of testosterone to estradiol and DHT does not change when treating Low T via injection of testosterone cypionate.

These ratios may be negatively affected with other Low T treatments (gels, patches, pellets, etc.).

While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA (prostate specific antigen).

Basically, prostate cancer is NOT one of the side effects of testosterone replacement therapy.

That aside, because PSA is essentially a tumor marker for prostate cancer, patients with a first-degree relative who has been diagnosed with prostate cancer and those with an elevated PSA level should proceed with caution and be monitored closely.

For men with a personal history of prostate cancer, treatment for Low T is considered contraindicated according to most sources.

It is important to note that testosterone replacement does not give you prostate cancer, but certainly elevated testosterone levels (even to the normal range) can cause an otherwise unnoticed prostate lesion to grow more aggressively.

Testosterone, in and of itself, is not a causative factor in the development of prostate cancer.

That myth has finally been debunked through countless studies over several years while more recent data now indicate that low serum testosterone levels are a potential predictor of high-risk prostate cancer.

The more interesting debate at this point is the potential consequence of increasing a mans testosterone level, even to a normal range, in the presence of an existing prostatic growth.

The findings of multiple studies over the years have ranged from testosterone appearing to be associated with promoting the transition of a common, low-grade lesion into one of a more aggressive nature, to testosterone actually contributing to cell death of the malignancy to no appreciable effect whatsoever.

Obviously the current data is inconclusive, however, it is becoming more and more apparent that as we ponder the safest recommendations, while peering through the lens of risk/benefit analysis, living with testosterone deficiency may indeed be the more risky endeavor.

The production of testosterone and sperm both are controlled by what is referred to as the Hypolthalamus-Pituitary-Gonadal Axis.

That is, the hypothalamus ( a portion of the forebrain responsible for the control of certain autonomic nervous system actions and pituitary gland activity) talks to the pituitary gland by mean of a chemical messenger (GnRH gonadotropin-releasing hormone).

The pituitary gland in turn will talk to the testicles (male gonads) also by means of different chemical messengers (LH luteinizing hormone and FSH follicular stimulating hormone).

Low T occurs when either this hormonal cycle fails to stimulate the testes to produce testosterone or more commonly when the testes themselves fail to respond to said stimulation.

When testosterone levels are normalized, either by natural means or through treatment of Low T, the brain reduces the stimulus to produce testosterone by secreting less GnRH.

Since this singular hormone controls both FSH and LH, the natural suppression of GnRH that occurs can reduce fertility.

Additionally, it is this same process that is responsible for the potential reduction in size and/or change in firmness of the testicles.

Other side effects of testosterone replacement therapy that are not part of normal functioning are increased red blood cell counts (erythrocytosis), potential decreases in good cholesterol or high-density lipoproteins (HDL), and increases in diastolic blood pressure (the lower of the two numbers reported in blood pressure readings).

The effects of high blood pressure are well known and the reasons for avoiding hypertension during TRT are no different from standard recommendations.

Increased number of red blood cells on the other hand, can lead to significant risk if not managed appropriately.

Think of red blood cells (RBCs) as the solid portion of the solution that is whole blood, and your hematocrit (HCT) the percentage of blood volume made up of RBCs.

If you add more solid to any solution without proportionately increasing the volume of the liquid it is suspended within, the result is a thicker solution.

Thickening of the blood then, is the end result of an increase in the number of RBCs.

Hematocrit values greater than 54.0% increase a patients risk factors for abnormal clotting, spleen enlargement, heart failure and other serious conditions.

If erythrocytosis does occur, it is typically rather easy to address. However if its assessment is overlooked, as is far too often the case, it can lead to potentially serious problems.

Certain side effects of testosterone replacement therapy are preparation specific. Gels, creams, and other topical agents can cause skin irritation and secondary exposure to women and children who come into contact with the medication via direct transfer.

Some untoward consequences of use of topicals is the wonderful odor (or fragrance, to steal Big Pharmas term) that is associated with it.

Failure rates are much, much higher for this type of medication owing to the inability of 30-40% of men to even absorb enough to improve their testosterone levels.

Virtually every medical treatment can cause adverse reactions. All things considered, the side effects of testosterone replacement therapy are quite manageable.

We know what to look for and how to intervene. With careful monitoring, it is entirely possible to treat and/or prevent significant problems these side effects may pose.

Ultimately it comes down to balance. Can we approach Low T treatment in such a way that allows for minimization of side effects while allowing for optimization of results? Absolutely!

What is necessary to achieve this is having providers who are open and honest about the benefits AND the risks associated with TRT. If you have questions, we would love the opportunity to talk with you and answer them.

Please Contact Us to schedule a no-obligation consultation in our clinic. If you are suffering from Low T and are ready to improve the quality of your life but are concerned about the side effects of testosterone replacement therapy (TRT), the dedicated providers at Testosterone Centers of Texas are ready to help you.

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Side Effects of Testosterone Replacement Therapy (TRT)

Nanomedicine Conferences | NanoPharma Conferences 2018 …

Posted on November 22, 2017 by Prof Baldwin

Sessions/Tracks

ConferenceSeries Ltdis a renowned organization that organizes highly notableconferencesthroughout the globe. Currently we are bringing forth14thInternational Conference and Exhibition onNanomedicine andPharmaceutical Nanotechnology(NanoMed 2018)scheduled to be held duringApril 16-18, 2018atAmsterdam, Netherlands.The conferenceinvites all the participants across the globe to attend and share their insights and convey recent developments in the field of Pharmaceutical Nanotechnology and Clinical Trials.

The main theme of the conference is Emerging Importance of Nanotechnology to Drive the Pharma Industry.

ConferenceSeries Ltdorganizes aconference seriesof 1000+ Global Events inclusive of 1000+ Conferences, 500+ Upcoming and Previous Symposiums and Workshops in USA, Europe & Asia with support from 1000 more scientificsocietiesand publishes 700+Open access Journalswhich contains over 50000 eminent personalities, reputed scientists as editorial board members.

14thInternational Conference and Exhibition onNanomedicineandPharmaceutical Nanotechnologyaims to bring together leading academic scientists, researchers and research scholars to exchange and share their experiences and research results on all aspects of Nanotechnology and Nanomedicine. It also provides a premier interdisciplinary platform for researchers, practitioners and educators to present and discuss the most recent innovations, trends, and concerns as well as practical challenges encountered and solutions adopted in the fields ofNanotechnologyand Nanomedicine.

Medicinehas developed throughout time but has remained forever concerned with the maintenance of health and thus the science of prevention and alleviation, and ultimately curing, of disease. To continue its development in new directions, medicine is now looking to nanomedicine, an emerging scientific specialty born from nanotechnology, which has grown up in the fields ofengineering, physics,chemistryandbiotechnology, and is now moving into medicine, with huge potential for expansion and development over the next decade and beyond.

As our knowledge of the human body continues to improve, nanotechnology will be developed to monitor, repair and control human biological systems at the molecular level. This conference will offer unique opportunities for developing new therapeutic approaches to diagnose, prevent, treat and eradicate life-threatening diseases and conditions (such as cancer and diabetes), as well as resolving pain and improving medical techniques (such as bone repair and surgical techniques), through various novel nanotechnological approaches.

Nanomedicineis a uniquely addressing the important challenges and advances in medicalnanoscale-structured materialand devices,biotechnology devicesand molecular machine systems andnanorobotics. NanoMed 2018 is a valuable information source for all players in the field academic, industrial and clinical researchers, pharmaceutical and biotechnology companies,regulatory authoritiesand others across the scientific community.

Track 1:NanomedicineandBiomedical Applications:

Nanomedicineis simply the application of nanotechnologies in a healthcare setting and the majority of benefits that have already been seen involve the use ofnanoparticlesto improve the behaviour ofdrug substances. Today, nanomedicines are used globally to improve the treatments and lives of patients suffering from a range of disorders including ovarian andbreast cancer, kidney disease, fungal infections,elevated cholesterol, menopausal symptoms, multiple sclerosis, chronic pain,asthmaand emphysema. The nanomedicines that are currently available are overcoming some of the difficulties experienced by normal medical approaches in delivering the benefit from thedrug moleculesused. In some cases the drugs have very little solubility in water and the human body struggles to absorb enough to treat the condition. In other cases, the drug molecule is absorbed well but the body removes the drug before it has had long enough to provide a benefit. Drugs may lead to side-effects due to poor delivery at the actual site of disease. For example, drugs that are targeting cancers must avoid healthy tissues and organs or damage can be caused. Nanomedicines therefore can play an important role in ensuring enough of the drug enters the body, that drug that does enter stays in the body for long periods and is targeted specifically to the areas that need treatment.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain; 10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany; 23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in USA:American Academy of Nanomedicine,Nano Canadian Society,American Nano Society,American Society for Nanomedicine,Society for Personalized Nano MedicineInternational Association of NanotechnologyandGraphene Stakeholders Association

Societies in Europe:Nanotechnology Industries Association,Royal Microscopical Society,Royal Society - Nanotechnology and Nanoscience,British Society for Nanomedicine,European Society for Nanomedicine,French Society for Nanomedicine,European NanoBusiness Association,European Society for Precision Engineering and Nanotechnology,Czech Nanotechnology Industries AssociationandErwin Schrdinger Society for Nanosciences

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 2:Design of Nanodrugs

To date, variousnanodrug systemshave been developed for different routes of administration, which include dendrimers,nanocrystals, emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles. Nanodrug systems have been employed to improve the efficacy, safety, physicochemical properties, and pharmacokinetic/pharmacodynamic profile of pharmaceutical substances. In particular, functionalized nanodrug systems can offer enhancedbioavailabilityof orally taken drugs, prolonged half-life of injected drugs (by reducing immunogenicity), andtargeted delivery to specific tissues. Thus,nanodrug systemsmight lower the frequency of administration while providing maximized pharmacological effects and minimized systemic side effects, possibly leading to better therapeutic compliance and clinical outcomes. In spite of these attractive pharmacokinetic advantages, recent attention has been drawn to the toxic potential of nanodrugs since they often exhibit in vitro and in vivo cytotoxicity, oxidative stress, inflammation, and genotoxicity

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 3:Design & Characterization of Nanosystems

Micro andNanosystemspublishes significant original work, topical reviews and guest edited issues ranging from technologies and systems to product innovation and new manufacturing processes with features at the micro and nanoscale. Applications for micro and nanosystems in areas such as health, environment, food, security and consumer goods are covered. The topics to be addressed include Lab-on-a-chip,microfluidics, nano-biotechnology, micro andnanomanufacturing, printed electronics and MEMS.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 4:NanomedicineandNanotechnology

Nanomedicine is a branch of medicine that applies the knowledge and tools of nanotechnology to the prevention and treatment of disease. Nanomedicine involves the use ofnanoscale materials, such as biocompatible nanoparticles andnanorobots, for diagnosis, delivery, sensing or actuation purposes in a living organism.Nanotechnologyhas many definitions but in general it is the use and application of materials with sizes in the nanometre range. Just as a millimetre is one-thousandth of a metre, a nanometre is one-millionth of a millimetre. In more understandable terms, a human hair is approximately 80,000 nanometres in diameter and the growing science and industry of nanotechnology utilises materials below 1000 nanometres. Benefits of working at this very small scale have been seen for many years over such diverse areas as electronics and energy storage to sunscreens and food packaging.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 5:Pharmaceutical Nanotechnology

Pharmaceutical Nanotechnologydeals with emerging new technologies for developing customized solutions fordrug delivery systems. The drug delivery system positively impacts the rate of absorption, distribution, metabolism, and excretion of the drug or other related chemical substances in the body. In addition to this the drug delivery system also allows the drug to bind to its target receptor and influence that receptors signaling and activity. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy asnanomaterials, and as devices likedrug delivery, diagnostic, imaging and biosensor.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 6:Synthesis of NanoparticlesforDrug Delivery

Synthesizingnanoparticlesfor pharmaceutical purposes such as drug preparation can be done in two methods. Bottom up process such as pyrolysis, inert gas condensation, solvothermal reaction, sol-gel fabrication and structured media in which hydrophobic compound such asliposomesare used as bases to mount the drug. Top down process such as attrition / milling in which the drug is chiseled down to form a nanoparticle.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 7:Regenerative MedicineandTissue Engineering

Tissue engineeringis a branch of regenerative medicine, itself a branch ofbiomedical engineering. Tissue engineering andregenerative medicineare concerned with the replacement or regeneration of cells, tissues (the focus of tissue engineers) or organs to restore normal biological function.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 8:Drug Delivery Research

Drug deliveryis an essential part ofpharmaceutical sciencesthat should be taken into account early in thedrug discoveryand development process. A drug that cannot be delivered to its site of action is essentially useless. Drug delivery is affected by the physico-chemical properties of the drug and formulation and the interplay of these factors with the transport, binding, and metabolism of the drug in the body. New tools are needed to accurately predict delivery properties of the compounds early during drug discovery, so that the best compounds can be identified for clinical studies. Another class of tools includes the delivery methods that facilitate delivery of hard-to-deliver compounds to the appropriate target sites. Delivery of gene-based drugs (DNA, oligonucleotides, siRNA) and proteins is a major challenge in pharmaceutical science. Nanotechnology can be used to improve drug delivery in these difficult cases. The development and use of nanoparticles in theformulationof these types of drugs is a major focus at CDR, and we welcome productive industrial partnerships to develop these tools for translational use.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 9:Novel Drug Delivery Systems

Novel Drug delivery systemis the advancedrug delivery systemwhich improvedrug potency,control drug releaseto give a sustained therapeutic effect, provide greater safety, finally it is to target a drug specifically to a desired tissue.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 10:Smart Drug Delivery Technology

With the unprecedented progresses ofbiomedical nanotechnologyduring the past few decades, conventionaldrug delivery systems(DDSs) have been involved into smart DDSs with stimuli-responsive characteristics. Benefiting from the response to specific internal or external triggers, those well-defined nanoplatforms can increase the drug targeting efficacy, in the meantime; reduce side effects/toxicities of payloads, which are key factors for improving patient compliance. In academic field, variety of smart DDSs have been abundantly demonstrated for various intriguing systems, such as stimuli-responsivepolymeric nanoparticles, liposomes, metals/metal oxides, and exosomes.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 11:Nano Pharmaceuticals

Nanopharmaceuticalsoffer the ability to detect diseases at much earlier stages and the diagnostic applications could build upon conventional procedures using nanoparticles. Nanopharmaceuticals represent an emerging field where the sizes of thedrug particleor a therapeutic delivery system work at thenanoscale. In the pharmaceutical industry, a long standing issue is the difficulty of delivering the appropriate dose of a particular active agent to specific disease site. Nanopharmaceuticals have enormous potential in addressing this failure of traditional therapeutics which offers site-specific targeting of active agents. Such precision targeting via nanopharmaceuticals reduces toxic systemic side effects, resulting in better patient compliance. In todays world economy, apharmaceutical industryfaces enormous pressure to deliver high-quality products to patients while maintaining profitability. Thereforepharmaceutical companiesare applying nanotechnology to enhance or supplement drug target discovery anddrug delivery. Nanopharmaceutical reduces the cost of drug discovery, design & development and enhances the drug delivery process. This results in the improvedResearch & Developmentsuccess rate which enables faster introduction of new, cost-effective products to the marketplace.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

Related Societies:

Societies in Asia:National Center for Nanoscience and Technology,Indian Society for Nanomedicine,Nano Technology Research AssociationandIndian Society of Nanomedicine.

Track 12:Nanobiotechnology

Nanobiotechnology,bionanotechnology, and nanobiology are terms that refer to the intersection of nanotechnology andbiology. This discipline helps to indicate the merger of biological research with various fields of nanotechnology. Concepts that are enhanced throughnanobiologyinclude:nanodevices(such asbiological machines), nanoparticles, and nanoscale phenomena that occurs within the discipline of nanotechnology. This technical approach to biology allows scientists to imagine and create systems that can be used forbiological research. Biologically inspired nanotechnology uses biological systems as the inspirations for technologies not yet created.

12thPharmaceutical Sciences andPharma Industry ConferenceFebruary 26- 27 2018,London, UK; 7thEuropeanBiosimilars Conference, April 26-27, 2018, Rome,Italy; 13thEuropean Pharma ConferencesMay 07-09, 2018 at Frankfurt,Germany; 4thMarine Drugs andNatural Products Conferences, June 11-13, 2018 atRome, Italy; 9thGlobal ExpertsMeeting on Neuropharmacology, June 18-19, 2018 atParis, France; 4thConference onAntibiotics Conference; June 14-15, 2018,Barcelona, Spain;Nanomedicine Conferences 2018 USA;10thPharmacology Conferencesduring July 30-August 01, 2018 at Barcelona,Spain; 8thEnvironmental Chemistry Conference, September 20-22, 2018 Berlin,Germany;Nanomedicine Conferences 2018 Asia;23rdConference on Nanomaterialsand Nanotechnology, March 15-16, 2018 at London,UK; 3rdConference On Nanomedicine, Drug Delivery, and Tissue Engineering, April 10 - 12, 2018 at Budapest,Hungary;World Congress on Nanotechnologyand Material Science, April 16-18, 2018 at Valencia,Spain; Conference onEmerging Trends in Materials Science and Nanotechnology, April 26-27, 2018 at Rome,Italy; 24thWorld Nano ConferenceMay 07-08, 2018 at Rome,Italy;Conference on Nanoscience& technology, May 21-22, 2018 at New York,USA; 20thConference on Nanotechnologyand Nanomedicine, July 9 - 10, 2018 at Prague, Czechia;Nanomedicine Conferences 2018 Asia;Conference on Nanotech & Nanobiotechnology, July 12-13, 2018 at Paris,France; 20thConference on Nanoscience, Nanotechnology and Advanced Materials, August 13 - 14, 2018 at Venice,Italy.

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Nanomedicine Conferences | NanoPharma Conferences 2018 ...

Nanomedicine – Overview – NIH Common Fund

Posted on November 21, 2017 by Prof Baldwin

Background

Nanomedicine, an offshoot of nanotechnology, refers to highly specific medical intervention at the molecular scale for curing disease or repairing damaged tissues, such as bone, muscle, or nerve. A nanometer is one-billionth of a meter, too small to be seen with a conventional lab microscope. It is at this size scale about 100 nanometers or less that biological molecules and structures operate in living cells.

The NIH vision for Nanomedicine is built upon the strengths of NIH funded researchers in probing and understanding the biological, biochemical and biophysical mechanisms of living tissues. Since the cellular machinery operates at the nanoscale, the primary goal of the program - characterizing the molecular components inside cells at a level of precision that leads to re-engineering intracellular complexes - is a monumental challenge.

The teams selected to carry out this initiative consist of researchers with deep knowledge of biology and physiology, physics, chemistry, math and computation, engineering, and clinical medicine. The choice and design of experimental approaches are directed by the need to solve clinical problems (e.g., treatment of sickle cell disease, blindness, cancer, and Huntingtons disease). These are very challenging problems, and great breakthroughs are needed to achieve the goals within the projected 10 year timeframe. The initiative was selected for the NIH Roadmap (now Common Fund) precisely because of the challenging, high risk goals, and the NIH team is working closely with the funded investigators to use the funds and the intellectual resources of the network of investigators to meet those challenges.

10 Year Program Design High Risk, High Reward

The Centers were funded with the expectation that the first half of the initiative would be more heavily focused on basic science with increased emphasis on application of this knowledge in the second five years. This was a novel, experimental approach to translational medicine that began by funding basic scientists interested in gaining a deep understanding of an intracellular nanoscale system and necessitated collaboration with clinicians from the outset in order to properly position work at the centers so that during the second half of the initiative, studies would be applied directly to medical applications. The program began with eight Nanomedicine Development Centers (NDCs), and four centers remain in the second half of the program.

Clinical Consulting Boards (CCBs)

The program has established Clinical Consulting Boards (CCBs) for each of the continuing centers. These boards consist of at least three disease-specific clinician-scientists who are experts in the target disease(s). The intent is for CCBs to provide advice and insight into the needs and barriers regarding resource and personnel allocations as well as scientific advice as needed to help the centers reach their translational goals. Each CCB reports directly to the NIH project team.

Translational Path

In 2011, the PIs of the NDCs worked with their CCBs to precisely define their translational goals and the translational research path needed to reach those goals by the end of the initiative in 2015. To facilitate this, the NIH project team asked them to develop critical decision points along their path. These critical decision points differ from distinct milestones because they may be adjusted based on successes, challenges, barriers, and progress. Similarly, the timing of these decision points may be revised as the centers progress. Research progress and critical decision points are revisited several times a year by the CCB and the NIH team, and when a decision point is reached, next steps are re-examined for relevance, feasibility and timing.

Transition plan

Throughout the program, various projects have been spun off of work at all the centers and most have received funding from other sources. This was by design as work at each center has been shifting from basic science to translational studies. Centers will not be supported by the common fund after 10 years. It is expected that work at the centers will be more appropriately funded by other sources. Pre-clinical targets will likely be developed, and the work at each center will be focused on a specific disease so the work will need to transition out of the experimental space of the common fund.

Support for the NIH Nanomedicine Initiative is provided by the NIH Common Fund, and a team of staff members from across the NIH oversees the program. You may direct questions or comments on the NIH Nanomedicine Initiative to Dr. Richard S. Fisher, Nanomedicine Project Team Leader (nano@nih.gov).

Excerpt from:
Nanomedicine - Overview - NIH Common Fund

Low Testosterone (Low T) Treatments – onhealth.com

Posted on November 11, 2017 by Prof Baldwin

What Is Testosterone?

Testosterone is a hormone that is necessary for proper muscular development and masculinity. Testosterone is made in the testes (testicles). Women also have testosterone, but in much smaller amounts than in men. If testosterone levels are below normal, a doctor may prescribe one of several types of treatments. However, there is debate about who needs to be treated.

Testosterone levels decrease as men age. Sometimes this lower level of testosterone is termed "andropause" or "male menopause." Symptoms of male menopause may not be caused by low testosterone, but additional research is needed. Many men do not show any symptoms of decreasing levels of testosterone.

Although osteoporosis (brittle bone disease) is usually thought of as occurring mainly in women, the disease in men is commonly caused by low testosterone. Low testosterone levels can cause bones to thin, weaken, and become more likely to fracture.

Low testosterone doesn't always interfere with sex, but it is possible. Some men with low testosterone may experience a drop in libido while others lose interest in sex completely. Low testosterone levels can make sex more difficult because it may be tougher to get or keep an erection. Low testosterone might not be the sole cause of low libido; stress, sleep deprivation, depression, and chronic medical illnesses can also alter a man's sex drive.

Some of the changes that may occur with low testosterone are nonspecific symptoms such as easy irritability, mood changes, poor concentration, and feeling fatigued or having less energy. However, these symptoms may be caused by a condition other than low testosterone.

One of the many functions of testosterone is to help produce sperm. When testosterone levels are low, the "sperm count" can also be low. If the sperm count is very low, the man may not be able to father a child.

Although increased age is the most common cause of decreased testosterone levels in men, there can be other causes. Other common causes include:

You might need to be tested for low testosterone if you have erectile dysfunction (ED), a very low sex drive, low sperm count, loss of body hair, decrease of muscle mass, and osteoporosis. Conditions other than low testosterone could be the underlying cause of one's symptoms. A doctor will want to rule out other conditions before diagnosing and treating low testosterone.

Tests for testosterone levels are done by sampling the blood early in the morning when levels of testosterone are highest. Your doctor may want to run a second test a few days later to check for consistency in testosterone levels measured. Normal testosterone levels range from about 300 to 1000 nanograms per deciliter (ng/dL), although some labs consider 200 ng/dL the cutoff for low testosterone. Your doctor will help interpret the tests for you.

If you are diagnosed with low testosterone, your primary care doctor may suggest you see a specialist such as an urologist or an endocrinologist. Not everyone with low testosterone will need or qualify for treatment. These specialists will help guide your treatment and design an approach to your low testosterone problem that is best for you.

Low testosterone treatment is designed to boost testosterone levels. Studies suggest this increase in testosterone can strengthen muscles, protect bones, and improve sex drive. Testosterone replacement therapy is only recommended for men who have blood levels that show low testosterone. Such treatments can have different effects from one man to another so it is difficult to predict the treatment outcomes for any one individual.

Testosterone injections are the least expensive form of testosterone treatment, but they can be painful. The shots are given about every 7 to 22 days and the body slowly absorbs the testosterone into the bloodstream. Injections can be given into the muscles or implanted as pellets. Testosterone levels can increase and then fall between shots.

Gel or patch treatments for low testosterone are placed directly on the skin. The hormone seeps out of the patch or gel and goes through the skin, and is slowly absorbed into the blood. Gels and patches are applied every day, and as a result, the level of testosterone remains fairly steady. A drawback to these treatments is they sometimes can cause itching, skin irritation, and blisters. In addition, women or children should not come in contact with skin that has been treated with a gel for 2 hours to avoid absorbing any testosterone.

Buccal patches are placed on the gums above the incisors (teeth) about every 12 hours and slowly release testosterone. They are not effective if swallowed. Buccal patches may cause a bitter taste, irritation to mouth tissues and gums, and may cause headaches. Fortunately, these side effects lessen over time. The patient can eat, drink, and kiss others while using buccal patches because they are not directly exposed to testosterone.

Although testosterone therapy has been tried in many individuals, the risks and benefits of this treatment over many years is still not known because such studies are still underway. Testosterone should not be given to men with untreated prostate cancer, untreated sleep apnea, or untreated breast cancer. In some men, testosterone therapy may need to be stopped if the risks outweigh the benefits.

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Transhumanism: The Anti-Human Singularity Agenda

Posted on November 4, 2017 by Prof Baldwin

Uri Dowbenko, Conscious ReporterWaking Times

At a TED-like techno-geek symposium in the 2014 film Transcendence, Artificial Intelligence guru Dr. Will Caster (Johnny Depp) is asked by an audience member, So you want to create your own god? And he answers, Isnt that what man has always done?

This smarmy remark is indicative of the hubris and arrogance of scientism, the belief that science can solve all the problems on this planet, while scientists can have fun playing god at the same time.

It could also have been the answer of Real-Life Techno-Wizard Ray Kurzweil, Googles Director of Engineering, whose book The Singularity is Near: When Humans Transcend Biology (2005), is ever so popular with scientific materialists who neither have the capacity nor the desire for spiritual evolution, but have a fervent belief that the shotgun marriage of man and machine is not only normal but something to be ardently pursued.

Simply put Kurzweils sociopathic quest for digital immortality is based on his fear of death. He claims to take 150 pills a day in order to still be half-alive when voodoo science will have succeeded in uploading his sorry-state mind into a digital facsimile of his former self into cyber-space.

No soul? No problem

Since materialist scientists dont understand multi-dimensional or spiritual realities, they are unconcerned about the details which they cant even fathom.

And what exactly is the Singularity supposed to be? Its a future mythological moment when machine (artificial) intelligence becomes more intelligent than human intelligence.Kurzweils thesis and fervent hope is that it will occur by 2045. He writes that it is a future period during which the pace of technological advance will be so rapid, its impact so deep, that human life will be irreversibly transformed The Singularity will represent the culmination of the merger of our biological thinking and existence with our technology, resulting in a world that is still human but transcends our biological roots. There will be no distinction, post-Singularity, between human and machine or between physical and virtual.

Does that sound like science or a religious Belief System (B***)?

Despite a lackluster script, Transcendence is worth seeing because it is another example of Illuminati predictive programming in popular sci-fi movies. After all todays Hollywood Illuminati make the best movies, which are also the best propaganda for preparing humanity to accept One World Global Techno-Feudalism.

Eliminating humanity altogether also appears to be one of their goals as they seem to believe that the Humanity Experiment for all intents and purposes is finished. And, if they realize their twisted vision, humanity will in actuality become completely superfluous on Terra.

A Charlie Sheen movie called The Arrival comes to mind, in which an alien race is terra-forming Planet Earth to fit their requirements which are far different from that of humanity. They need a darker and more humid climate like the one in which dinosaurs roamed the earth. Obviously geo-engineering spraying chemtrails around the world and other forms of weather manipulation using HAARP technology, etc. are used in this so-called climate change scenario. Of course humans are always blamed for using the petro-chemical technology with which they have enslaved humanity in this age.

Now the plan to get rid of those pesky humans appears to have accelerated as the movie Transcendence introduces the concept of transhumanism to the hand-held electronics-addled masses.

Transhumanism itself was coined by Aldous Huxleys brother, biologist Julian Huxley, in 1957, when he wrote The human species can, if it wishes, transcend itself not just sporadically, an individual here in one way, an individual there in another way, but in its entirety, as humanity. We need a name for this new belief. Perhaps transhumanism will serve: man remaining man, but transcending himself, by realizing new possibilities of and for his human nature. (Religion Without Revelation, p.27)

Even Illuminati Gofer Julian Huxley called it a belief, since he knew that immortality was the Illuminati goal in life. After all, transhumanism has been aptly named the Rapture of the Geeks.

Reviewers of the movie have failed to put the film in context with real-life science, wherein techno-mischief makers like Google have plenty of cash to make their dream of transhumanism a reality. It should be noted that Google has been buying up companies like Boston Robotics, which makes killer robots, Deep Mind Technologies, an artificial intelligence company, NEST Labs, which plans to monitor your life through interactive appliances called the Network of Things and Project Calico, a genetic engineering project to defeat death itself, as their hype goes.

Scooping up human DNA into a gigantic database also seems to be one of Googles goals. A Google-wannabe subsidiary called 23andMe, founded by the wife of a Google founder, has as its stated goal creating the worlds largest secure, private database of genotypic and phenotypic information that can be used for comparison analysis and research. Of course Google has included a disclaimer in the Terms of Use which states Genetic information you share with others could be used against your interests. And this wonderful Monopoly Capitalism zinger as well By providing any sample, you acquire no rights in any research or commercial products that may be developed by 23andMe or its collaborating partners.

According to a New York Magazine article called The Google of Spit, by the end of 2013, 23andMe had extracted and analyzed DNA from 650,000 people, making it one of the biggest genetic banks in the world. Like any other Google scam, you sign away your rights but this time its your genetic program its your DNA.

Will Google be able harvest your soul in the future?

As New York Magazine put it In September, just a month after Wojcicki [wife of Google founder Sergey Brin] and Brin announced their separation, Google announced the launch of a new venture called Calico. Though its exact mission and purpose remain unclear, the general idea is for Calico to solve death, as Time magazine put it, in an uncanny echo of Wojcickis [founder of 23andMe] promise to solve health.

Solve health? Solve death? Theres no so-called problem these Arrogant Techno-Creeps cant handle

And then theres DARPA (Defense Advanced Research Project Agency), the Pentagons black-magic voodoo-science department that wants to create among other things replicant super-soldiers as portrayed by Rutger Hauer in the movie Blade Runner or Kurt Russel in Soldier for the Illuminatis future wars which will then inevitably morph into autonomous killing robots as seen in the RoboCop and Terminator films.

Coincidentally in a book by Wikileaks founder Julian Assange called When Wikileaks Met Google (2014), we discover Surprise! Google was actually partially funded by the sinister DARPA, the Pentagon Devils Workshop. Heres a footnote from the book

Acknowledgments, in The Anatomy of a Large-Scale Hypertextual Web Search Engine, Sergey Brin, Lawrence Page (Computer Science Department, Stanford University, 1998): The research described here was conducted as part of the Stanford Integrated Digital Library Project, supported by the National Science Foundation under Cooperative Agreement IRI-9411306. Funding for this cooperative agreement is also provided by DARPA and NASA, and by Interval Research, and the industrial partners of the Stanford Digital Libraries Project, archive.today/tb5VL.

In an excellent documentary called Google and the World Brain, WIRED magazine writer Kevin Kelly asked Google founder Larry Page back in the olden days, Why would anyone want a new search engine when we have Alta Vista?

And Page replied, Its not to make a search engine. Its to make an A.I.

The documentary also quotes Ray Kurzweil before he was hired as Googles Director of Engineering saying We talked to Google about their quest to digitize all knowledge and then create an A.I.

Googles corporate goal appears to be not only to steal all words, books, images, video, music, etc. through its search engine and other subsidiaries like Google Books, You Tube, etc. but then to monetize this wholesale theft on a worldwide scale.

This global library of information can then be transformed into a super-cyber-godlike Artificial Intelligence, which literally may become tantamount to SkyNet of Terminator movie fame.

In Transcendence, the Johnny Depp character turns into an uploaded cyberspace version of his former human self. Disguised as a cautionary tale, the movie is presented as a fait accompli, since the mad scientists of Google and DARPA are undoubtedly working day and night to initiate the so-called Singularity a confluence of the so-called GRIN technologies Genetic, Robotic, Information processing, and Neuro-technological processing.

By merging Artificial Intelligence, Nanotechnology, and Synthetic Biology, augmented by geo-engineering and Genetically Modified (GM or weaponized) food crops, these voodoo priests and rabbis of transhumanism are attempting to create a consensual virtual reality in which humans have become irrelevant because they are not augmented like those who have A.I. enhanced techno-gadgets, granting them super-powers, super-knowledge or super-intelligence. These synthetic or artificial siddhis (spiritual powers), they believe, will make them much more than mere mortal humans.

Like SkyNet, the all-powerful Artificial Intelligence in Jim Camerons Terminator movies, which sees humans as the enemy because it has no use for humans, Johnny Depps uploaded super-mind in Transcendence becomes a kind of cyber-god which craves more energy and power, not only to survive, but to expand itself and control everything on Earth.

Or as the Depp character tells his TED fanboys at the symposium Imagine a machine with the full range of human emotion. Its analytical power will be greater than the collective intelligence of every person in the history of the world. Some scientists refer to this as the singularity. I call it transcendence.

The problem with Singularity is that these materialistic scientists dont even understand what consciousness is, yet believe that uploading a human brain into a computer environment is somehow akin to transcending humanity even if its just a synthetic copy of a persons memories, etc.

They call it H+ which implies a superior human (Homo Superior) as opposed to Homo Sapiens.

The reality may be a little different, since the Illuminati plan for humanity is genetically engineering Homo Sapiens into Homo Deus.

Or is it Homo Insanus?

After all. No soul? No problem

Even Nobel Prize winner Stephen Hawking has written about his foreboding regarding transhumanism and the movie Transcendence in a UK Independent op-ed piece.

Of course Hawking doesnt say that Google is equivalent to Skynet, but he appears to be concerned about the dangers of an A.I. arms race, since mega-corporations like the sinister Google and Apple, as well as the sinister DARPA, are using their formidable resources of money and high-tech labor to try to produce an A.I. as soon as possible. Hawkins writes its tempting to dismiss the notion of highly intelligent machines as mere science fiction. But this would be a mistake, and potentially our worst mistake in history.

And why does Hawking sound a warning about the dangers of A.I.? Because he knows that as a cripp(term used by the handicapped as short for cripple), he would have been terminated as a useless eater.

The movies premise that Artificial Super Intelligence, a/k/a The Uploaded Johnny Depp 2.0 is a threat to humanity is of serious concern to Hawking and that dismissing the film as just science fiction could be the worst mistake in history, implies that film director Jim Camerons scenario in Terminator 2, wherein the A.I. based SkyNet overpowers the humans is not simply an idle threat but a very real problem since morality-and-ethics-free robots who are soul-less beings are an existential threat to humanity itself.

Hawking argues that developments in so-called digital personal assistants like Apples Siri and Google Now show a current I.T. Information Technology arms race which pales against what the coming decades will bring.

Success in creating A.I. would be the biggest event in human history, writes Hawking Unfortunately, it might also be the last, unless we learn how to avoid the risks.

Another opponent of the Singularity agenda is Bill Joy, who wrote an article for WIRED Magazine called Why the future doesnt need us: Our most powerful 21st-century technologies robotics, genetic engineering, and nanotech are threatening to make humans an endangered species.

Joy quotes from Kurzweils book The Age of Spiritual Machines, wherein he finds himself most troubled by this passage

The New Luddite Challenge

On the other hand it is possible that human control over the machines may be retained. In that case the average man may have control over certain private machines of his own, such as his car or his personal computer, but control over large systems of machines will be in the hands of a tiny elite just as it is today, but with two differences.

Due to improved techniques the elite will have greater control over the masses; and because human work will no longer be necessary the masses will be superfluous, a useless burden on the system. If the elite is ruthless they may simply decide to exterminate the mass of humanity. If they are humane they may use propaganda or other psychological or biological techniques to reduce the birth rate until the mass of humanity becomes extinct, leaving the world to the elite.

In the book, you dont discover until you turn the page that the author of this passage is Theodore Kaczynski the Unabomber.

By the way Luddite is a derogatory term for anyone who is opposed to technological so-called advances for any reason whatsoever.

And of course what the alleged Unabomber Ted Kaczynski, who was a mind control experimentation victim at Harvard, meant in his screed was that propaganda is actually so-called news, psychological techniques is the Malthusian belief system that there are too many humans on earth, and biological techniques means genetically modified foods and vaccines to cull the herd. In other words, he is predicting the Illuminati vision for the future a future bereft of what Illuminati Kingpin Henry Kissinger called useless eaters.

Then Bill Joy, cofounder and Chief Scientist of Sun Microsystems, gets positively metaphysical, writing I think it is no exaggeration to say we are on the cusp of the further perfection of extreme evil, an evil whose possibility spreads well beyond that which weapons of mass destruction bequeathed to the nation-states, on to a surprising and terrible empowerment.

Perfection of extreme evil now thats a mouthful.

Even Elon Musk, of Tesla Car and SpaceX Rocket Fame, is allegedly wary of A.I. According to CNN, he told an audience at MIT that we should be very careful about Artificial Intelligence, warning it may be our biggest existential threat, adding that with Artificial Intelligence, we are summoning the demon.

When so-called High Profile Illuminati Gofer Scientist-Entrepreneurs refer to Artificial Intelligence as Perfection of Extreme Evil and Summoning the Demons b******! You Better Pay Attention!

URI DOWBENKO is the author of Homegrown Holography, Bushwhacked: Inside Stories of True Conspiracy and Hoodwinked: Watching Movies with Eyes Wide Open. He is also the founder and publisher of http://www.ConspiracyPlanet.com, http://www.ConspiracyDigest.com, http://www.AlMartinRaw.com, and http://www.InsiderIntelligence.com, as well as the publisher of The Conspirators: Secrets of an Iran Contra Insider by Al Martin. Uris latest project is called New Improved Memoirs, Its your life story Without the hassle of writing it. (http://www.NewImprovedMemoirs.com) a professional service for people who want to leave behind a customized autobiography, in other words a published book, as a legacy for their friends, family, and posterity. You can visit Uri at http://www.UriDowb

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Transhumanism: The Anti-Human Singularity Agenda was last modified: June 18th, 2016 by WakingTimes

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Transhumanism: The Anti-Human Singularity Agenda

4 Easy Ways to Live a Healthy Lifestyle (with Pictures)

Posted on October 16, 2017 by Prof Baldwin

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Four Parts:Choosing Healthy FoodsGetting Some ExerciseAvoiding Unhealthy HabitsRemembering Good HygieneCommunity Q&A

Being healthy involves more than eating an occasional salad or going for a short walk once every few weeks, but while you'll need to put in some effort, your health is well worth it. To live a healthy lifestyle, consistently choose healthy foods, fit more exercise and physical activity into your daily routine, and practice good hygiene. You'll also need to avoid unhealthy habits, like fad dieting and neglecting sleep. Making lifestyle improvements may require some gradual adjustment, but improved health is readily accessible once you commit to it. [1]

Part 1

Part 2

Exercise in your neighborhood. Go for a jog or take your dog for a walk. Make sure that you move at a moderate pace for at least 30 minutes.

Part 3

Part 4

Clean your feet. Make sure to scrub between your toes to prevent athlete's foot and unpleasant odors.

How can I stop myself from eating so much?

wikiHow Contributor

Eat a high calorie breakfast! This will decrease your hunger for the rest of the day as well as speed up your metabolism. Make sure you drink a lot of water, and drink a glass before eating, since you will become full faster. Using smaller plates has a psychological effect which decreases the amount of food you eat. Also, try to limit the amount of sugar and empty calories you take in and eat more lean protein which will keep you full longer and less hungry.

How many hours should teenagers sleep?

wikiHow Contributor

Teenagers should get between eight and ten hours of sleep each night to be healthy.

What foods that I can eat for a few days to cleanse my body?

wikiHow Contributor

Lemon, cucumber, and basically any kind of veggie.

Should I stop eating sourdough bread? Is it considered a white bread, and is it unhealthy?

wikiHow Contributor

You don't need to stop eating anything completely if you really like it; everything is okay in small doses. Sourdough isn't generally considered white bread; it's considered its own kind of bread, and some think it's healthier than plain white bread. Whole wheat bread is healthier, though.

What is a good atmosphere for a healthy lifestyle?

wikiHow Contributor

A good atmosphere for a healthy lifestyle includes being around other people that have the same drive to be healthy, not around those that encourage unhealthy behaviors. Also, maintaining a clean house (especially kitchen) will make you feel like you're more in control of your life and thus will help you lead a better life. Last but not least, remember that health is not a destination but a journey, so you must always be working towards a healthier body and life.

Is there an easy way to sleep well?

wikiHow Contributor

Yes. Just allot yourself enough time to get a good night's sleep. Stick to a regular sleep schedule as best as you can, rather than sleeping and waking up at different times from day to day. Do not exercise within 2 hours of sleeping. Do not eat large amounts of food before going to sleep. Avoid caffeine or sugary foods and drinks before sleeping. Try not to use your TV, computer, phone, tablet or any other screen shortly before sleeping. Dim your lights before you go to sleep. All of this, combined with living a healthier lifestyle all around should greatly increase your quality of sleep.

How can I lose fat in the thigh and tummy area?

How much sleep should I get if I am 12 years old?

wikiHow Contributor

12-year-olds need about 9-10 hours of sleep every night to be healthy.

What happens if I only get 4 hours of sleep a night?

wikiHow Contributor

Once in a while it really won't hurt you, but if it happens all the time your immune system will be affected, and you'll be more likely to get sick. You'll also be prone to fatigue, headaches, trouble concentrating, and other impairments.

Is jogging a way to lose drastic weight?

wikiHow Contributor

Yes, if you do it regularly and eat as few carbs as possible.

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4 Easy Ways to Live a Healthy Lifestyle (with Pictures)

Testosterone Replacement Therapy Seattle WA – Dr Kate Kass

Posted on October 15, 2017 by Prof Baldwin

If youre like most men, you ignore health issues large and small, toughing it out until your body feels out of whack or accepting a slow decline in mood, motivation, and libido that you just chalk up to normal aging.

Perhaps you visit a primary care physician once a year who says everythings fine, but you have a growing belly, no energy, and your erectile function isnt what it used to be. Maybe you have an expanding medicine cabinet of pharmaceuticals that are causing unwanted side effects. Sound familiar?

Thats a shame because you dont have to live with subpar health. There are many ways to optimize your health at any age and restore the youthful energy and vigor you used to depend on. It could be your thyroid, leaky gut, side effects to medications, or elevated cortisol levels that are laying you low.

And it could be low testosterone. Low testosterone affects your sexual function, but it can also be the root cause of fatigue, weight gain, sleep apnea, and a whole laundry list of less-than-desirable symptoms. But the good news is, if you seek out the right help, you can prevent disease and regain a sense of wellness and vitality.

Thats where Dr. Kate Kass comes in. A licensed primary care physician, Dr. Kass specializes in functional medicine, age management, and mens sexual wellness.

She seeks out cutting-edge therapies, tests, and protocols from the worlds of conventional and functional medicine to diagnose the root problem and create an effective treatment plan customized to your specific symptoms and concerns. (Read more about Dr. Kasss philosophy)

Starting around a mans mid-30s, total testosterone declines at a rate of 10 percent each decade and more than 40 percent of males 40 and above have a testosterone deficiency.

It is during this time that men experience andropause, the male counterpart to menopause. Testosterone is tricky. It doesnt just affect sexual performance. In fact, you actually may have satisfactory erectile function but still test below optimal levels for testosterone.

Why does this matter? Because testosterone is a factor in all sorts of bodily functions. When your levels are optimal, testosterone protects against cardiovascular disease, reduces blood sugar, improves lean muscle mass, increases bone density, decreases cholesterol, and increases libido and sexual performance.

Its a powerful tool in preventing disease and improving your quality of life. When you have low testosterone, however, you may experience the following symptoms:

If any of these symptoms strike a chord, you may have a testosterone decline, and you should seek out an expert for a comprehensive evaluation.

As a specialist in testosterone replacement therapy in Seattle, Dr. Kass believes that you dont have to resign yourself to unwanted symptoms of aging.

In her practice, she has helped male patients regain vitality and their libido, manage their weight, and improve their mood - all while slowing the aging process and preventing disease.

Dr. Kass has extensive training and experience in all the safe, effective methods of testosterone delivery, and is one of the few practitioners trained to offer testosterone via pellet implantation.

Dr. Kass fine tunes your treatment, and manages the various adjunctive hormones that also play a role in optimizing testosterone function and your overall health.

postmenopausal hormone replacement treatment – webmd.com

Posted on October 13, 2017 by Prof Baldwin

If youre looking for relief from menopause symptoms, knowing the pros and cons of hormone replacement therapy (HRT) can help you decide whether its right for you.

HRT (also known as hormone therapy, menopausal hormone therapy, and estrogen replacement therapy) uses female hormones -- estrogen and progesterone -- to treat common symptoms of menopause and aging. Doctors can prescribe it during or after menopause.

After your period stops, your hormone levels fall, causing uncomfortable symptoms like hot flashes and vaginal dryness, and sometimes conditions like osteoporosis. HRT replaces hormones your body no longer makes. Its the most effective treatment for menopause symptoms.

You might think of pregnancy when you think of estrogen. In women of child-bearing age, it gets the uterus ready to receive a fertilized egg. It has other roles, too -- it controls how your body uses calcium, which strengthens bones, and raises good cholesterol in the blood.

If you still have your uterus, taking estrogen without progesterone raises your risk for cancer of the endometrium, the lining of the uterus. Since the cells from the endometrium arent leaving your body during your period any more, they may build up in your uterus and lead to cancer. Progesterone lowers that risk by thinning the lining.

Once you know the hormones that make up HRT, think about which type of HRT you should get:

Estrogen Therapy: Doctors generally suggest a low dose of estrogen for women who have had a hysterectomy, the surgery to remove the uterus. Estrogen comes in different forms. The daily pill and patch are the most popular, but the hormone also is available in a vaginal ring, gel, or spray.

Estrogen/Progesterone/Progestin Hormone Therapy: This is often called combination therapy, since it combines doses of estrogen and progestin, the synthetic form of progesterone. Its meant for women who still have their uterus.

The biggest debate about HRT is whether its risks outweigh its benefits.

In recent years, several studies showed that women taking HRT have a higher risk of breast cancer, heart disease, stroke, and blood clots. The largest study was the Womens Health Initiative (WHI), a 15-year study tracking over 161,800 healthy, postmenopausal women. The study found that women who took the combination therapy had an increased risk of heart disease. The overall risks of long-term use outweighed the benefits, the study showed.

But after that, a handful of studies based on WHI research have focused on the type of therapy, the way its taken, and when treatment started. Those factors can produce different results. One recent study by the Fred Hutchinson Cancer Research Center reveals that antidepressants offer benefits similar to low-dose estrogen without the risks.

With all the conflicting research, its easy to see why HRT can be confusing.

If you have these conditions, you may want to avoid HRT:

HRT comes with side effects. Call your doctor if you have any of these:

Your doctor can help you weigh the pros and cons and suggest choices based on your age, your family's medical history, and your personal medical history.

SOURCES:

Garnet Anderson, PhD, director, public health sciences division, Fred Hutchinson Cancer Research Center, Seattle.

Cleveland Clinic: Hormone Therapy (HT), Understanding Benefits and Risks.

John Hopkins Medicine: Hormone Therapy.

Journal of the American Medical Association, Oct. 2, 2013.

Main Line Health: Estrogen, Progesterone, and Menopause.

JoAnn E. Manson, MD, DrPH, chief, preventative medicine division, department of medicine, Brigham and Womens Hospital, Boston.

National Cancer Institute: Menopausal Hormone Therapy and Cancer Fact Sheet.

National Heart, Lung, and Blood Institute: Womens Health Initiative.

National Institutes of Health: WHI Study Data Confirm Short-Term Heart Disease Risk of Combination Hormone Therapy for Postmenopausal Women.

National Institute on Aging: Hormones and Menopause."

North American Menopause Society: Hormone Therapy for women in 2012.

Office on Womens Health, U.S. Department of Health and Human Services: Menopausal hormone therapy (MHT).

U.S. Preventative Services Task Force: Understanding Task Force Recommendations: Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions.

Excerpt from:
postmenopausal hormone replacement treatment - webmd.com

Erectile Dysfunction and Testosterone Replacement Therapy

Posted on October 12, 2017 by Prof Baldwin

Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, a sense of well-being, and sexual function.

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

As a man ages, the amount of testosterone in his body naturally gradually declines. This decline starts after age 30 and continues throughout life. Some causes of low testosterone levels are due to:

Without adequate testosterone, a man may lose his sex drive, experience erectile dysfunction, feel depressed, have a decreased sense of well-being, and have difficulty concentrating.

Low testosterone can cause the following physical changes:

The only accurate way to detect the condition is to have your doctor measure the amount of testosterone in your blood. Because testosterone levels fluctuate throughout the day, several measurements will need to be taken to detect a deficiency. Doctors prefer, if possible, to test levels early in the morning, when testosterone levels are highest.

Note: Testosterone should only be used by men who have clinical signs and symptoms AND medically documented low testosterone levels.

Testosterone deficiency can be treated by:

Each of these options provides adequate levels of hormone replacement; however, they all have different advantages and disadvantages. Talk to your doctor to see which approach is right for you.

Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure. All men considering testosterone replacement therapy should undergo a thorough prostate cancer screening -- a rectal exam and PSA test -- prior to starting this therapy.

In general, testosterone replacement therapy is safe. It is associated with some side effects, including:

Laboratory abnormalities that can occur with hormone replacement include:

If you are taking hormone replacement therapy, regular follow-up appointments with your doctor are important.

Like any other medication, directions for administering testosterone should be followed exactly as your doctor orders. If you are unsure or have any questions about testosterone replacement therapy, ask your doctor.

SOURCE:

Get-Back-On-Track.com.

The Hormone Foundation.

News release, FDA.

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Erectile Dysfunction and Testosterone Replacement Therapy

Transhumanism – Encyclopedia Britannica | Britannica.com

Posted on October 9, 2017 by Prof Baldwin

social and philosophical movement

Transhumanism, social and philosophical movement devoted to promoting the research and development of robust human-enhancement technologies. Such technologies would augment or increase human sensory reception, emotive ability, or cognitive capacity as well as radically improve human health and extend human life spans. Such modifications resulting from the addition of biological or physical technologies would be more or less permanent and integrated into the human body.

The term transhumanism was originally coined by English biologist and philosopher Julian Huxley in his 1957 essay of the same name. Huxley refered principally to improving the human condition through social and cultural change, but the essay and the name have been adopted as seminal by the transhumanism movement, which emphasizes material technology. Huxley held that, although humanity had naturally evolved, it was now possible for social institutions to supplant evolution in refining and improving the species. The ethos of Huxleys essayif not its lettercan be located in transhumanisms commitment to assuming the work of evolution, but through technology rather than society.

The movements adherents tend to be libertarian and employed in high technology or in academia. Its principal proponents have been prominent technologists like American computer scientist and futurist Ray Kurzweil and scientists like Austrian-born Canadian computer scientist and roboticist Hans Moravec and American nanotechnology researcher Eric Drexler, with the addition of a small but influential contingent of thinkers such as American philosopher James Hughes and Swedish philosopher Nick Bostrom. The movement has evolved since its beginnings as a loose association of groups dedicated to extropianism (a philosophy devoted to the transcendence of human limits). Transhumanism is principally divided between adherents of two visions of post-humanityone in which technological and genetic improvements have created a distinct species of radically enhanced humans and the other in which greater-than-human machine intelligence emerges.

The membership of the transhumanist movement tends to split in an additional way. One prominent strain of transhumanism argues that social and cultural institutionsincluding national and international governmental organizationswill be largely irrelevant to the trajectory of technological development. Market forces and the nature of technological progress will drive humanity to approximately the same end point regardless of social and cultural influences. That end point is often referred to as the singularity, a metaphor drawn from astrophysics and referring to the point of hyperdense material at the centre of a black hole which generates its intense gravitational pull. Among transhumanists, the singularity is understood as the point at which artificial intelligence surpasses that of humanity, which will allow the convergence of human and machine consciousness. That convergence will herald the increase in human consciousness, physical strength, emotional well-being, and overall health and greatly extend the length of human lifetimes.

The second strain of transhumanism holds a contrasting view, that social institutions (such as religion, traditional notions of marriage and child rearing, and Western perspectives of freedom) not only can influence the trajectory of technological development but could ultimately retard or halt it. Bostrom and American philosopher David Pearce founded the World Transhumanist Association in 1998 as a nonprofit organization dedicated to working with those social institutions to promote and guide the development of human-enhancement technologies and to combat those social forces seemingly dedicated to halting such technological progress.

means by which humans react to changes in external and internal environments.

the process involved in knowing, or the act of knowing, which in its completeness includes perception and judgment. Cognition includes all processes of consciousness by which knowledge is accumulated, such as perceiving, recognizing, conceiving, and reasoning. Put differently, cognition is an...

in human beings, the extent of an individuals continuing physical, emotional, mental, and social ability to cope with his environment.

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Transhumanism - Encyclopedia Britannica | Britannica.com

Immortality Medicine | Prometheism.net – Part 2

Posted on October 4, 2017 by Prof Baldwin

Aging in Aspen is different than in other places.

Walk the malls or the streets, and youll see people of a certain age, call it 60-plus, who glow with life. Take to the steep roads or trails just after dawn and you will be passed by geriatric joggers and cyclists, mixed in with the millennials and Gen-Xers, riding or running up the substantial hills, getting miles in before breakfast.

Aspenites of all ages embrace their physicality. They are in shape and they are either living the later years of their lives to the fullest, on their own terms, or actively pursuing healthy practices so that their futures will also be bright.

At a plethora of events like last weeks Aspen Brain Lab and the Aspen Institutes Spotlight Health, presented earlier this summer, Aspenites engage with each other and with new, sometimes revolutionary ideas in health care. Make no mistake, the outsized financial resources of the community allow many to benefit from the best health care that money can buy.

Human Longevitys intentions, if successful, would transform the status quo of the medical, pharmaceutical and health insurance industries.

Lets face it, this is an amazing place to grow old.

A POTENTIALLY NEW PARADIGM

Last week, in a lovely private home at the base of Smuggler Mountain, a small group of Aspenites gathered to hear of a budding revolution in health care. As the assembled, ranging in age from late 30s to their mid 70s, relaxed in chairs and on sofas in the well-appointed living room, sipping wine and sampling spring rolls, they listened to a presentation that proposed the potential to change the way they look at their own health. And their future, as well.

While the first nourishing rain in months pelted the roof and shrouded the Aspen Mountain views from the house, J. Craig Venter, who gained fame, acclaim and fortune in the early 2000s for his role in the quest to sequence the human genome, explained how his latest creation, Human Longevity, Inc., in La Jolla, California, is working to turn the world of health care upside down.

Venter, a vibrant 70-year-old, co-founded Human Longevity to provide people with the most complete and intensive genetic and physical assessments of their health that has ever existed. These road maps show clients, in intimate detail, the exact condition of their bodies at a given moment in time, and what pitfalls may exist for the future based upon their genetic makeup.

Sitting comfortably with his toy poodle, Darwin, on his lap, the bearded Venter detailed his vision for the company that has raised over $300 million in capital from investors, including Celgene and GE Ventures. The goal is to give people, and eventually health care companies, advance information about pre-existing health issues so that the focus can be on prevention as a health care option, rather than continuing the long entrenched tradition of fixing people after they have already developed maladies or life threatening diseases.

Perhaps because of Venters earlier success with the human genome, his project is receiving much attention. Last year he was here in Aspen to address the Ideas Festival and speak at the Charlie Rose Weekend event. This spring he was the subject of a Forbes Magazine cover story on the project and has also been featured in documentaries produced by production companies as disparate as NOVA and Red Bull TV. Though he is not without his detractors, some of whom find him arrogant and infused with an outsized disrespect for established medical conventions, Venter is once again on a quest for change.

Like Amazon revolutionizing shopping, Tesla challenging the automotive industry and Uber disrupting transportation, Human Longevitys intentions, if successful, would transform the status quo of the medical, pharmaceutical and health insurance industries.

THE HEALTH NUCLEUS PROGRAM

The product of the Human Longevity is knowledge on a disk.

Clients currently come to a luxurious facility in La Jolla for a physical assessment unlike any that has previously been available to human beings. Called the Health Nucleus, the procedure calls for a complete review and analysis of a clients physical health. When completed, clients walk away with a disk that details both their DNA and their current state of health.

The first element of the Health Nucleus, and perhaps most revolutionary, is the process of a whole genome sequencing of each client, the actual mapping of their personal genetic code, or their DNA. Every cell of a person has 23 pairs of chromosomes. In each chromosome there are millions of pieces of information. Think of these as individual words or letters that are unique to any and every individual. This is the genetic story of our lives. Add it all up and there are 6.4 billion characters of code in each of us, Venter said.

This data tells us everything about our physical makeup. The color of our eyes and hair, how tall we will grow, whether we are right-handed or left-handed. And it also tells us what diseases we may be susceptible to, or even pre-ordained for. From cancers to cardiovascular issues, which combined account for two-thirds of all deaths in this country, to metabolic and neurological issues, the genome sequencing provides insights into what potential health issues we should be aware of.

At the completion of the whole genome sequencing, the information is analyzed and cross-referenced with the largest database of full genotypic information that currently exists. A 500-page report is prepared, including with a short summation, for each client. When we did the first genome sequencing in 2000 we built a $50 million computer and the cost of the process was $100 million. Today, thanks to the progress in computing power, we are able to do a sequence in 12 minutes at a cost of closer to $1,000, Venter said to the intrigued group. The computing power we have today is 1,350 times greater than when we first started sequencing the genome.

The second component of the Health Nucleus is a full body and brain Magnetic Resonance Imaging, or MRI. This state of the art technology uses high frequency radio waves to produce vivid, vibrant and previously unimaginably clear images of internal organs. And, in contrast to previous technologies like cat scans, it requires no radiation.

This MRI will show, with a multitude of cross sections, what is inside your body and the state of health it is in. Ever want to see the size of your hippocampus in full Technicolor? How about your kidney in 3-D? At the conclusion of the session, as many as 18,000 images of the clients body can be accessed.

These exams are not just for the aged. In fact, the ability for the Health Nucleus examinations to offer a base line of health information can change the way younger people plan for their health care throughout their lives. We have performed assessments on people from 18 to 99 years old, Venter said. He recommended that the procedures are appropriate for people, beginning in their 20s and 30s.

REAL LIFE MEANING

But beyond just the novelty and wonder of seeing what the inside of your body looks like, the MRI has the capability of identifying real life-threatening issues that may go undetected in other types of physicals. Forty percent of the people who undergo the assessments have something to address. Two-and-a-half percent who come in have cancers, Venter said. We see lots of aneurysms that are treatable and incidents of prostate cancers in men.

Early detections are extremely rewarding, Venter said with a degree of irony, before explaining his own experience with the assessments. Last year I underwent a physical with my doctor and showed no indications of any issues. I then went through our Health Nucleus assessment and discovered, to my shock, that I had high-grade prostate cancer. After undergoing treatment last November, Venter is now cancer free.

Choking up in front of the group, Venter also told the story of his science mentor, partner and friend, Nobel laureate in medicine Hamilton Smith, 85, who found he had a deadly lymphoma while undergoing an evaluation using the Health Nucleus assessment. He, too, underwent treatment and is doing well. Ham would likely not be alive today if we had not begun this project.

The Health Nucleus project is still in its development stages and there are issues to be reckoned with. Colon cancers, for example, cannot be identified reliably as of yet, so colonoscopies are still recommended. Stat News, an online health journalism site produced by Boston Globe Media, recently presented an article stating that there are components of the human genome that have yet to be decoded that could affect the accuracy of current sequencing. Finding physicians who have the capability to review the data properly can be a challenge. And the costs of the Health Nucleus screenings are not currently covered by insurance and must be paid out of pocket.

But Venter is aggressively moving forward. It was announced that Human Longevity will be opening 10 new clinics throughout the nation; unfortunately Aspen is not currently on the docket. And perhaps most importantly, HLI has introduced two new versions of its consumer assessments at price points of $4,900 or $7,500, considerably less than the original Health Nucleus Platinum program that costs $25,000. Expectations are those costs will come down in the future as the program scales up.

While immortality may never be an option, increasing ones life span by a number of years by predicting and preventing treatable disease may well be the wave of the future. When I asked J. Craig Venter how long he wants to live, he looked wistfully across the room toward his wife, Heather. Well, Id like to see this project through, he said with a stiff upper lip. Then, in a much softer voice, And Id like to spend as much time with my wife as I possibly can.

For those who can afford it and are interested in knowing as much about their health options as is possible, and potentially reducing the onset of preventable disease, the Health Nucleus testing may be very attractive. As Aspenite Joe Nevin, who hosted the gathering, asked, Why wouldnt you want to know?

Original post:Aspen Times Weekly: How Long Do You Want to Live? Aspen Times

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Immortality Medicine | Prometheism.net - Part 2

Testosterone Replacement Therapy Vivacity Clinic of Las …

Posted on October 4, 2017 by Prof Baldwin

The medical community agrees that testosterone begins to decline gradually in most men by the time they reach the age of 30. If left unchecked, testosterone levels will continue to decline as you age, meaning that the average 50-year-old will have far less testosterone than the average 35-year-old, even though individuals are in a state of testosterone decline.

The effects of diminishing testosterone should be hardly noticeable for most men in their 30s. Once you hit 50, however, the effects may truly start to set in. Your sex drive may be reduced, you may have difficulty getting or maintaining an erection, your overall mood and energy may drop, and you may feel symptoms of irritability and even depression. Fortunately, the availability of testosterone replacement therapies for men over 50 means that you can break this cycle and regain at least some of the vitality you possessed as a young man.

VCLV Testosterone Replacement Therapy (TRT)offers physician prescribed and medically supervised Testosterone Therapy programs helping patients enter a cost effective and comprehensive Low Testosterone Treatment program designed to treat adult men over the age of 35 suffering from symptoms and problems associated with Low-T,hypogonadism and andropause also known as "male menopause".

Testosterone Replacement Therapy (TRT) with injectable testosterone, testosterone cream or gel can help men with low testosterone levels. Testosterone treatment is carefully formulated to help alleviate symptoms due to male menopause - Low T.

Treat low testosterone symptoms: loss of energy; low sex drive; erectile dysfunction; loss of muscle tone; irritability; depression; insomnia, feeling tired all the time bordering on fatigue; loss of focus and drive.

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What is Nanomedicine – The British Society for Nanomedicine

Posted on October 2, 2017 by Prof Baldwin

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What is Nanomedicine - The British Society for Nanomedicine

Christian transhumanism? Yes, says pastor – WND.com

Posted on September 7, 2017 by Prof Baldwin

WASHINGTON A Christian pastor from Florida is promoting acceptance of some forms of transhumanism, saying believers should be open to finding an ethical alternative to the complete rejection of the scientific, technical and philosophical transhumanist movement that has already begun.

Rev. Christopher Benek, associate pastor of family ministries and mission at First Presbyterian Church in Fort Lauderdale, writes in the Christian Post that its time for the development of Christian transhumanism.

If you have read the The American Conservatives recent postings about the evolving transhumanist movement, you have likely developed reasonable concerns, Benek wrote. People should be dismayed at Zoltan Istvans misguided article in TAC from two weeks ago entitled: The Growing World of Libertarian Transhumanism. And, if one believes that Istvans transhumanism represents all transhumanists, then Kai Weiss follow-up piece Transhumanism is Not Libertarian, Its an Abomination, is correct and appropriately titled. But these two depictions do not represent the majority of transhumanist thought. As such I would request: Please folks do not throw the transhumanist-baby out with Zoltan Istvans bathwater. There is an ethical transhumanist alternative: Christian Transhumanism.

Benek says Christians can make a positive moral impact on the debate over transhumanism rather than throw the baby out with the bathwater.

To be clear, transhumanism at its core is not some sci-fi or superhero that will happen in 100 years, concept, he wrote. Transhumanism is happening right now. As a pastor serving a local congregation, I see proof of transhumanism in my congregation every day.

Get up to speed on transhumanism, as mankind seeks an alternative way to immortality without God. Watch the DVD, Transhumanism: Recreating Humanity

By that, Benek says, people who have hip and knee implants, pacemakers installed and get Lasik eye surgery to enhance vision are dabbling in transhumanism.

Humanity is evolving beyond its current limitations by way of exponentially increasing advances in science and technology, he says.

Rev. Christopher Benek

He cautions that Christians should not conclude transhumanism is all bad.

I say this because holding an overly dogmatic position in a quickly developing technological movement is likely to leave one looking hypocritical in the long run, he says. Case in point: If scientists figure out a way to affordably use CRISPR technology to edit the human genome to eliminate the possibility of getting cancer no one is reasonably going to reject that technological advancement.

Like the reporting you see here? Sign up for free news alerts from WND.com, Americas independent news network.

Benek also promotes a new organization called the Christian Transhumanist Association, for which he serves as founding chairman. He says the group has 755 members and 2,000 Facebook likes.

Just this past June of 2017, the CTA formalized the addition of a seven-member academic advisory council made up of renowned academics with the intent of establishing a center of positive engagement at the intersection of Christianity, Transhumanism, and the academic world,' he writes. It appears that, every single day, the CTAs numbers and influence are on the rise.

He added, Christians have the opportunity to radically influence the direction that transhumanism takes in the future. Morally guided, community discerned, Christian transhumanism offers a legitimate alternative to utilitarian, atheistic transhumanism.

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Christian transhumanism? Yes, says pastor - WND.com

Who’s afraid of transhumanism? (We all should be) – America Magazine

Posted on September 7, 2017 by Prof Baldwin

It is difficult to define, but its a growing movement. Transhumanism has its own central organization (Humanity+), its own demographic base (Silicon Valley), even its own political formation (the Longevity Party).

On one level the movements goals appear benign. One of its key documents, Principles of Extropy, sums up the basic values of transhumanism: perpetual progress, self-transformation, practical optimism, intelligent technology, open society, self-direction, and rational thinking. The local Rotary Club would not object.

But the fundamental ambition of transhumanism is more problematic. Its architects champion a use of technology to accelerate the evolution of humanity so radically that at the end of the process humanity as such would disappear. A superior posthuman being would emerge. According to Wikipedia, Transhumanism is the intellectual and cultural movement that affirms the possibility and desirability of fundamentally improving the human condition through applied reason, especially by developing and making widely available knowledge to eliminate aging and to greatly enhance human intellectual, physical, and psychological capacities. From its inception, the abolition of human death and aging has been one of the goals of transhumanism as it engineers a new being freed from the biological constraints of the current human condition.

Two of the movements philosophers, Max More and David Pearce, have developed eloquent apologies for the transhumanist creed. But they also indicate the movements more ominous philosophical themes.

The very concept of human nature disappears in much transhumanist literature. The human body is dismissed as something of secondary, accidental importance. Mr. More argues that the self has to be instantiated in some physical medium but not necessarily one that is biologically humanor biological at all. Once again in the history of philosophy, the body has become a mere container for the human mind. The body is perceived as an impediment to the minds development rather than humanitys natural site for thought. Tellingly, in this new version of anthropological dualism, the soul has disappeared; it is the sovereign self, a liberated will yearning for omniscience and omnipotence, that remains. Unsurprisingly, Ayn Rand is one of the movements favorite novelists.

Not only is humanity freed from its biological finitude in the transhumanist dream; it no longer enjoys any unique status as a subject of rights. Max More claims that creatures with similar levels of sapience, sentience, and personhood are accorded similar status no matter whether they are humans, animals, cyborgs, machine intelligences, or aliens. The religious claim that human beings are made in Gods image and the political claim that humans deserve respect because of their transcendental status crumble. Little of Renaissance humanism remains in a movement that glorifies the posthuman being to come and considers current humanity a fleeting phenomenon with no particular, intrinsic dignity.

The moral philosophy of the transhumanist movement is broadly utilitarian. One cannot judge the morality of a particular act in isolation; its goodness depends on whether it contributes to the global pleasure of a future humanity and ultimately a posthumanity.

David Pearce has developed an influential version of this transhumanist utilitarianism in his book The Hedonistic Imperative. For Mr. Pearce, the greatest ethical task of humanity is to eliminate all suffering in the world. Just as medical science has eliminated physical suffering through anesthetics, we should now use technology to conquer all psychic suffering. Mr. Pearce endorses a vigorous use of genetic engineering and pharmacology to achieve this goal of an anguish-free humanity and posthumanity. He even supports the use of such technology to abolish pain in wild animals.

Mr. Pearces ethics represent the perfectionist side of the transhumanist project. He describes the mission to eliminate suffering as paradise engineering and the naturalization of Heaven. The state of a properly engineered posthumanity in the future is nothing less than paradisal: Our descendants may live in a civilization of serenely motivated high achievers, animated by gradients of bliss.

It is a strange utopia. Our current opioid epidemic is a cautionary tale against the dream of a sedated humanity. We are still reeling from the totalitarian dream where millions perished in the name of a radiant future that required some lethal cutting of ethical corners in the meantime. The enthusiastic transhumanist revival of eugenics is a cause for alarm. Is there any place for people with disabilities in this utopia? Why would we want to abolish aging and dying, essential constituents of the human drama, the fountainhead of our art and literature? Can there be love and creativity without anguish? Who will flourish and who will be eliminated in this construction of the posthuman? Does nature itself have no intrinsic worth? Finally, isnt the transhumanist dream of liberating humanity from its biological and psychic creaturehood simply a high-tech surrender to an ancient temptation, Ye shall be as gods?

Whos afraid of transhumanism? I am. We all should be.

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Who's afraid of transhumanism? (We all should be) - America Magazine

tech-life-game-news – Christian Post (blog)

Posted on September 7, 2017 by Prof Baldwin

Transhumanism is a movement that seeks to find the solutions to mankind problems in robotics, genetic modification and general human involvement in what would be perceived to be natural processes. This movement is often perceived as the enemy of religion because the views contrast so strongly, but that need not be the case.

To learn more about transhumanism, robotics and related concerns, visit Human Paragon, a leading resource for anyone in the Transhumanism community and anyone seeking more information. For info on how this connects to Christianity, read on.

Were All After the Same Thing

Christians and transhumanists both want to better mankind, to reduce poverty, suffering and illness the world over. These two goals are the same, and any groups that so strongly share the same ideals should not be the enemy of one another.

Transhumanists seek to better understand the genetic makeup of mankind in order to find ways of tweaking this. It is artificial evolutionand if as Christians we can accept evolution and the way that this ties into our beliefs, then surely we can so the same with the science of transhumanism. After all, it is our duty on this earth to love and to careto be altruistic. And there is nothing more loving and caring the using our natural talents and intelligence to mold the world around us in order to remove the problems we face every day.

Is It What God Would Want?

God created mankind in his image, God created a world that he deemed to be perfect, so why should we change that, right? Well you only need to look around you to see that humanity is anything but perfect and that we have near-destroyed the world He created.

If finding solutions to these problems is wrong, then how can causing these problems be right? How can it be okay to build nuclear weapons, to cause climate change, to destroy thousands of acres of natural forestry and to care the extinction of thousands of Gods creatures? None of this is right and if we continue as we are, the well only make that situation worse.

Drastic times call for drastic measures and when the world is in ruin and there seems to be little hope, the idea of transhumanism could be the answer. And if we really are created in his image then that means that everything we are came from him; everything we know and everything we have at our disposal is his. So, transhumanism could therefore not be seen as something against God, but a way of performing Gods will, a way of righting the wrongs.

Im not saying thats the case, Im just saying that there are many ways to look at this and that the ideas of groups like the transhumanists should not be so readily dismissed on religious grounds.

Learn More

As mentioned above, Human Paragon is a great place to learn more about this, and its important that you do. These techniques and ideals might actually help to bring parts of the Christian story to life. Its the only way any of us can live as long as Methuselah, the only way we can truly scale the heights that our lord set for us.

So, lets not fight it and lets at least try to understand it.

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Global Nanomedicine Industry 2017 Market Growth, Trends and Demands Research Report – MENAFN.COM

Posted on September 7, 2017 by Prof Baldwin

(MENAFN Editorial) iCrowdNewswire - Sep 4, 2017

The Global Nanomedicine Market 2017 Industry Research Report' report provides a basic overview of the industry including its definition, applications and manufacturing technology. Then, the report explores the Global major industry players in detail.

The Global Nanomedicine Market Research Report 2017 renders deep perception of the key regional market status of the Nanomedicine Industry on a global level that primarily aims the core regions which comprises of continents like Europe, North America, and Asia and the key countries such as United States, Germany, #China and Japan.

Complete report on Nanomedicine market report spread across 116 pages, profiling 12 companies and supported with tables and figuresavailable @

The report on 'Global Nanomedicine Market is a professional report which provides thorough knowledge along with complete information pertaining to the Nanomedicine industry propos classifications, definitions, applications, industry chain summary, industry policies in addition to plans, product specifications, manufacturing processes, cost structures, etc.

The potential of this industry segment has been rigorously investigated in conjunction with primary market challenges. The present market condition and future prospects of the segment has also been examined. Moreover, key strategies in the market that includes product developments, partnerships, mergers and acquisitions, etc., are discussed. Besides, upstream raw materials and equipment and downstream demand analysis is also conducted.

Report Includes:-

The report cloaks the market analysis and projection of 'Nanomedicine Market on a regional as well as global level. The report constitutes qualitative and quantitative valuation by industry analysts, first-hand data, assistance from industry experts along with their most recent verbatim and each industry manufacturers via the market value chain. The research experts have additionally assessed the in general sales and revenue generation of this particular market. In addition, this report also delivers widespread analysis of root market trends, several governing elements and macro-economic indicators, coupled with market improvements as per every segment.

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Global Nanomedicine market competition by top manufacturers/players, with Nanomedicine sales volume, Price (USD/MT), revenue (Million USD) and market share for each manufacturer/player; the top players including: GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck & Co. Inc., Nanosphere Inc., Pfizer Inc., SigmaTau Pharmaceuticals Inc., Smith & Nephew PLC, Stryker Corp, Teva Pharmaceutical Industries Ltd., UCB (Union chimique belge) S.A

The report is generically segmented into six parts and every part aims on the overview of the Nanomedicine industry, present condition of the market, feasibleness of the investment along with several strategies and policies. Apart from the definition and classification, the report also discusses the analysis of import and export and describes a comparison of the market that is focused on the trends and development. Along with entire framework in addition to in-depth details, one can prepare and stay ahead of the competitors across the targeted locations. The fact that this market report renders details about the major market players along with their product development and current trends proves to be very beneficial for fresh entrants to comprehend and recognize the industry in an improved manner. The report also enlightens the productions, sales, supply, market condition, demand, growth, and forecast of the Nanomedicine industry in the global markets.

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Every region's market has been studied thoroughly in this report which deals with the precise information pertaining to the Marketing Channels and novel project investments so that the new entrants as well as the established market players conduct intricate research of trends and analysis in these regional markets. Acknowledging the status of the environment and products' up gradation, the market report foretells each and every detail.So as to fabricate this report, complete key details, strategies and variables are examined so that entire useful information is amalgamated together for the understanding and studying the key facts pertaining the global Nanomedicine Industry. The production value and market share in conjunction with the SWOT analysis everything is integrated in this report.

Table of Contents

1 Nanomedicine Market Overview 2 Global Nanomedicine Market Competition by Manufacturers 3 Global Nanomedicine Capacity, Production, Revenue (Value) by Region (2011-2016) 4 Global Nanomedicine Supply (Production), Consumption, Export, Import by Regions (2011-2016) 5 Global Nanomedicine Production, Revenue (Value), Price Trend by Type 6 Global Nanomedicine Market Analysis by Application 7 Global Nanomedicine Manufacturers Profiles/Analysis

8 Nanomedicine Manufacturing Cost Analysis 9 Industrial Chain, Sourcing Strategy and Downstream Buyers 10 Marketing Strategy Analysis, Distributors/Traders 11 Market Effect Factors Analysis 12 Global Nanomedicine Market Forecast (2016-2021) 13 Research Findings and Conclusion

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Global Nanomedicine Industry 2017 Market Growth, Trends and Demands Research Report - MENAFN.COM

Nanobiotechnology Applications, Markets and Companies, 2017-2021 & 2026 – GlobeNewswire (press release)

Posted on September 7, 2017 by Prof Baldwin

Dublin, Sept. 07, 2017 (GLOBE NEWSWIRE) -- The "Nanobiotechnology Applications, Markets and Companies" report from Jain PharmaBiotech has been added to Research and Markets' offering.

The report starts with an introduction to various techniques and materials that are relevant to nanobiotechnology. It includes some of the physical forms of energy such as nanolasers. Some of the technologies are scaling down such as microfluidics to nanofluidic biochips and others are constructions from bottom up. Application in life sciences research, particularly at the cell level sets the stage for role of nanobiotechnology in healthcare in subsequent chapters.

An increasing use of nanobiotechnology by the pharmaceutical and biotechnology industries is anticipated. Nanotechnology will be applied at all stages of drug development - from formulations for optimal delivery to diagnostic applications in clinical trials. Many of the assays based on nanobiotechnology will enable high-throughput screening. Some of nanostructures such as fullerenes are themselves drug candidates as they allow precise grafting of active chemical groups in three-dimensional orientations. The most important pharmaceutical applications are in drug delivery. Apart from offering a solution to solubility problems, nanobiotechnology provides and intracellular delivery possibilities. Skin penetration is improved in transdermal drug delivery. A particularly effective application is as nonviral gene therapy vectors. Nanotechnology has the potential to provide controlled release devices with autonomous operation guided by the needs.

Nanomedicine is now within the realm of reality starting with nanodiagnostics and drug delivery facilitated by nanobiotechnology. Miniature devices such as nanorobots could carry out integrated diagnosis and therapy by refined and minimally invasive procedures, nanosurgery, as an alternative to crude surgery. Applications of nanobiotechnology are described according to various therapeutic systems. Nanotechnology will markedly improve the implants and tissue engineering approaches as well. Of the over 1,000 clinical trials of nanomedicines, approximately 100 are selected and tabulated in major therapeutic areas. Other applications such as for management of biological warfare injuries and poisoning are included. Contribution of nanobiotechnology to nutrition and public health such as supply of purified water are also included.

Future nanobiotechnology markets are calculated on the basis of the background markets in the areas of application and the share of this market by new technologies and state of development at any given year in the future. This is based on a comprehensive and thorough review of the current status of nanobiotechnology, research work in progress and anticipated progress. There is definite indication of large growth of the market but it will be uneven and cannot be plotted as a steady growth curve. Marketing estimates are given according to areas of application, technologies and geographical distribution starting with 2016. The largest expansion is expected between the years 2021 and 2026.

Profiles of 252 companies, out of over 500 involved in this area, are included in the last chapter along with their 183 collaborations.The report is supplemented with 51 Tables, 31 figures and 800 references to the literature.

Key Topics Covered:

Part I: Applications & Markets

1. Introduction

2. Nanotechnologies

3. Nanotechnologies for Basic Research Relevant to Medicine

4. Nanomolecular Diagnostics

5. Nanopharmaceuticals

6. Role of Nanotechnology in Biological Therapies

7. Nanodevices & Techniques for Clinical Applications

8. Nanooncology

9. Nanoneurology

10. Nanocardiology

11. Nanopulmonology

12. Nanoorthopedics

13. Nanoophthalmology

14. Nanomicrobiology

15. Miscellaneous Healthcare Applications of Nanobiotechnology

16. Nanobiotechnology and Personalized Medicine

17. Nanotoxicology

18. Ethical and Regulatory Aspects of Nanomedicine

19. Research and Future of Nanomedicine

20. Nanobiotechnology Markets

21. References

Part II: Companies

22. Nanobiotech Companies

For more information about this report visit https://www.researchandmarkets.com/research/xnnnck/nanobiotechnology

Jury Punishes AbbVie for False Advertising in First MDL Verdict – Legal Examiner

Posted on September 6, 2017 by Prof Baldwin

In June of 2014, the U.S. Judicial Panel on Multidistrict Litigation (JPML) consolidated all federally filed testosterone-replacement therapy (TRT) lawsuits into one court in the Northern District of Illinois. District Judge Matthew Kelley decided early on that trials would be scheduled based on the type of TRT product used. Since AbbVies product AndroGel leads the market in testosterone-replacement products, the first bellwether trials each involve AndroGel.

In the second case to be tried, a Chicago jury determined that manufacturer AbbVie should pay $150 million to an Oregon man who suffered a heart attack after taking the drug.

The plaintiff first started taking AndroGel in 2008, and used it through 2012. He suffered a heart attack that year, at 49 years old. He claimed that AbbVie failed to warn of the risks associated with their drug, which he claims include blood clots, heart attacks, and strokes. He also claimed that the company misled consumers when they aggressively advertised the drug as a solution for age-related low-T.

The jury came back with a split verdict. They awarded the plaintiff $150 in punitive damages, stating that AbbVie was liable for false marketing and fraudulent misrepresentation. At the same time, however, they concluded that the plaintiffs heart attack was not caused by AbbVies negligence, and did not award him any compensatory damages.

AbbVie blamed the plaintiffs heart attack on other risk factors, including high blood pressure and cholesterol, obesity, and smoking. The company is expected to appeal the verdict.

This is only the second of seven planned bellwether trials to go to a jury. (An earlier trial ended in a mistrial, and is expected to begin again in September.) The consolidated litigation includes about 4,000 lawsuits, with all plaintiffs claiming that the manufacturers failed to warn of cardiovascular and blood-clot-related risks.

Even if the verdict doesnt stand, it sends a powerful message to AbbVie, and shows that juries will likely react unfavorably to AbbVies aggressive million-dollar advertising campaign. The company marketed the drug as an effective treatment for low-T, which it described as a condition with the same symptoms of normal male aging, like fatigue, muscle loss, and drop in libido.

The FDA, however, approved testosterone replacement only for medically diagnosed low testosterone, or hypogonadism. Studies have shown that many of the men who were convinced to take the drug never had a single testosterone test to diagnose any medical condition.

In 2014, for example, researchers reported that 40.2 percent of U.S. men did not have a testosterone test in the 180 days before beginning therapy, and 50 percent had only one test (doctors usually conduct at least two to get an average reading).

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Jury Punishes AbbVie for False Advertising in First MDL Verdict - Legal Examiner

Australian Market Declines – Nasdaq

Posted on September 6, 2017 by Prof Baldwin

Shutterstock photo

(RTTNews.com) - The Australian stock market is declining on Wednesday following the weak lead overnight from Wall Street amid heightened geopolitical tensions after North Korea's nuclear missile test on Sunday.

In late-morning trades, the benchmark S&P/ASX 200 Index is down 25.60 points or 0.45 percent to 5,680.60, off a low of 5,662.70 earlier. The broader All Ordinaries Index is declining 24.70 points or 0.43 percent to 5,743.10.

In the banking sector, ANZ Banking, Westpac, Commonwealth Bank and National Australia Bank are lower in a range of 0.9 percent to 1.4 percent.

Gold miners are advancing after gold prices rallied overnight. Newcrest Mining is advancing 1 percent and Evolution Mining is rising more than 2 percent.

Oil stocks are also higher after crude oil prices rose almost 3 percent overnight. Woodside Petroleum is adding 0.3 percent, Oil Search is advancing almost 1 percent and Santos is rising almost 2 percent.

AGL Energy said it has made no commitment to sell its Liddell coal-fired power station in NSW nor extend its life beyond 2022. The energy producer's shares are declining almost 1 percent.

Acrux and pharma giant Eli Lilly have agreed to terminate their licensing deal for Axiron, a testosterone replacement therapy for men. Shares of Acrux are losing almost 23 percent.

On the economic front, Australia will release second-quarter numbers for its gross domestic product or GDP today.

In the currency market, the Australian dollar is higher against the U.S. dollar on Wednesday after the greenback fell following the release of weak U.S. durable goods data. In early trades, the local unit was trading at US$0.7995, up from US$0.7975 on Tuesday.

On Wall Street, stocks closed sharply lower on Tuesday, partly reflecting geopolitical concerns following news North Korea conducted a major nuclear test on Sunday. Traders also kept an eye on any developments in Washington, as lawmakers returned following the August recess.

The Dow plunged 234.25 points or 1.1 percent to 21,753.31, the Nasdaq tumbled 59.76 points or 0.9 percent to 6,375.57 and the S&P 500 slumped 18.70 points or 0.8 percent to 2,457.85.

The major European markets ended mixed on Tuesday. While the German DAX Index rose by 0.2 percent, the French CAC 40 Index dipped by 0.3 percent and the U.K.'s FTSE 100 Index fell by 0.5 percent.

Crude oil futures touched the highest in four weeks Tuesday, supported by a stronger dollar and concerns about rigs in the Gulf of Mexico. October WTI oil climbed $1.37 or 2.9 percent to settle at $48.66 a barrel on the New York Mercantile Exchange, the highest since August 11.

For comments and feedback: contact editorial@rttnews.com

http://www.rttnews.com

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Global Nanomedicine Industry 2017 Market Growth, Trends and Demands Research Report – MENAFN.COM

Nanobiotechnology Applications, Markets and Companies, 2017-2021 & 2026 – GlobeNewswire (press release)

Jury Punishes AbbVie for False Advertising in First MDL Verdict – Legal Examiner

Australian Market Declines – Nasdaq