Published: February, 2014

Millions of American men use a prescription testosterone gel, patch, or injection to boost levels of the manly hormone. The ongoing marketing blitz promises that treating "low T" this way can make men feel more alert, energetic, mentally sharp, and sexually functional. However, legitimate safety concerns linger, as explained in the February 2014 issue of the Harvard Men's Health Watch.

"Because of the marketing, men have been flooded with information about the potential benefit of fixing low testosterone, but not with the potential costs," says Dr. Carl Pallais, an endocrinologist and assistant professor of medicine at Harvard Medical School. "Men should be much more mindful of the possible long-term complications."

Some studies have found that men taking testosterone have more cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. Yet the evidence is mixed, with some studies showing a lower cardiac risk with testosterone therapy and no apparent effect on prostate cancer.

In such uncertain times, men should take a cautious approach, Dr. Pallais says.

"I can't tell you for certain that taking testosterone raises the risk of heart problems and prostate cancer, or that it doesn't," Dr. Pallais says. "We need a large study with multiple thousands of men followed for many years to figure it out."

Until then, here are some tips for taking a cautious approach to testosterone therapy:

Read the full-length article: "Is testosterone therapy safe? Take a breath before you take the plunge"

Read more:
Is testosterone replacement therapy safe ... - Harvard Health

Benefits of Testosterone for Women: The Case for Testosterone Replacement in Aging Women

Television, the internet, and magazine ads all target men with products that address the drop in testosterone that occurs with age, but despite being classified as a male hormone, testosterone is also produced by women. While its true that men produce far more testosterone than women do, during the early reproductive years, women have 10 times more testosterone than estrogen within the body, leading experts to believe that its really testosterone loss that results in many of the symptoms women go through in midlife, such as low libido, fatigue, low muscle tone, weight gain, and loss of mental focus.1

Testosterone for women has become a hot button issue as women begin to realize that they too are at risk for deficiencies since testosterone levels drop with age in women as well. Around the world, testosterone therapy is being used to treat the symptoms of testosterone deficiency in both pre- and post-menopausal women as research continues to show that healthy testosterone levels are essential for the physical and mental health of both men and women.

Since the ovaries are responsible for producing both estrogen and testosterone, as the ovaries age, they produce less estrogen and testosterone.2 As women enter pre-menopause, testosterone production is reduced, and once women reach menopause, its common for them to produce less than half the testosterone they did previously. Every woman becomes at risk for testosterone deficiency as she ages, and women who go through a hysterectomy or oophorectomy have an even higher risk of dealing with low testosterone levels.

Women who begin experiencing a testosterone deficiency often notice many of the same symptoms men deal with as they deal with low T levels. Low levels of testosterone in women often lead to an increased risk of osteoporosis, since low T levels can leach away strength from the skeleton.3 Low levels can also lead to an increased risk of gaining weight since testosterone levels have been linked with fat mass in women in studies published in the American Journal of Epidemiology.4

A report published in the Journal of Womens Health even showed that testosterone deficiencies could be a risk factor for the development of heart disease in women.5 Since cardiovascular disease is the number one killer of postmenopausal women, this is an interesting hypothesis that underscores the importance of balanced hormones in women, including testosterone.

Both women and men may experience a wide variety of symptoms with low testosterone, such as fatigue, weight gain, low libido, and mental fogginess. Testosterone therapy has the potential to relieve these symptoms. Low libido is one of the most common complaints among aging women, and studies show that treating women with testosterone can significantly improve their sex drive.6

For women going through menopause, testosterone therapy often provides symptom relief. Studies show that testosterone therapy in menopausal women can relieve the symptoms of menopause, including urinary urgency, incontinence, vaginal dryness, and hot flashes.7 Testosterone therapy may also help protect against cardiovascular events, dilating blood vessels and increasing blood flow, as well as offering a reduced risk of Type 2 diabetes by lowering insulin resistance.8

While some buy into the myth that testosterone therapy may increase the risk of breast cancer, studies show that instead of increasing a womans risk for the disease, taking testosterone may actually help prevent breast cancer.9 Other benefits of testosterone women may experience include improve focus and mental clarity, reduced fatigue, reduced anxiety, improved bone density, and increases in lean muscle mass.

Women suffering from testosterone deficiency can benefit from choosing bio-identical hormone replacement therapy (BHRT). Since bio-identical hormones have the same molecular structure as the hormones a womans body naturally produces, hormones can be properly used and naturally metabolized and excreted by the body.

When compared to traditional hormone replacement therapy, BHRT offers a much lower risk of side effects. BHRT is tailor made to meet each womans specific needs, ensuring that hormone levels are increased safely to prevent negative side effects.

Women who are aging or who have undergone a hysterectomy or oophorectomy are at risk for declining testosterone levels. Aging women who experience low libido, poor concentration, symptoms of menopause, or other symptoms related to low levels of testosterone can benefit from testosterone therapy.10 Choosing bio-identical hormone replacement therapy can benefit women by reducing the symptoms of menopause, preventing osteoporosis, protecting the heart, increasing lean muscle mass, and improving overall quality of life.11

For more information contact us at http://www.renewmetoday.com to take the hormone health test, and find out where your nearest office is.

References

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Benefits of Testosterone for Women Renew Me Today

For the Consumer

Applies to testosterone: buccal patch extended release

Along with its needed effects, testosterone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking testosterone:

Get emergency help immediately if any of the following symptoms of overdose occur while taking testosterone:

Some side effects of testosterone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Applies to testosterone: buccal film extended release, compounding powder, intramuscular solution, nasal gel, subcutaneous implant, transdermal cream, transdermal film extended release, transdermal gel, transdermal ointment, transdermal solution

The most frequently reported side effects with this drug are edema, acne, site pain, injection site erythema, cough or dyspnea during or immediately after injection.

The most frequently reported side effects with testosterone topical are skin reaction (16.1%) and allergic contact dermatitis (up to 37%).[Ref]

Very common (10% or more): Testosterone topical: Skin reaction (16.1%), burn-like blisters (12%), itching, allergic contact dermatitis (up to 37%)Common (1% to 10%): Acne, induration, burningUncommon (0.1% to 1%): Alopecia, erythema, rash (including rash popular), pruritus, dry skin, folliculitis (testosterone topical)Frequency not reported: Seborrhea, urticaria, male pattern baldness, hirsutism injection site inflammationPostmarketing reports: Angioedema, angioneurotic edema, hyperhidrosis, discolored hair, leukocytoclastic vasculitis[Ref]

Very common (10% or more): Accelerated growthCommon (1% to 10%): Increased estradiol, hypogonadismUncommon (0.1% to 1%): Increased blood testosteroneFrequency not reported: Signs of virilization in women (e.g., hoarseness, acne, hirsutism, menstrual irregularity, clitoral enlargement, and alopecia), precocious puberty (in prepubertal males)Postmarketing reports: Hyperparathyroidism, prolactin increased, testosterone increased[Ref]

Very common (10% or more): Testosterone buccal film: Gingivitis (32.6%)Common (1% to 10%): Diarrhea, oily stools (due to IM injection oily solvent); Testosterone topical: Gastroesophageal reflux disease, gastrointestinal bleeding, gum or mouth irritation (9.2%), taste bitter, gum pain, gum tenderness, gum edema, taste perversionUncommon (0.1% to 1%): NauseaRare (less than 0.1%): Abdominal painFrequency not reported: Abdominal disorder, intraabdominal hemorrhagePostmarketing reports: Vomiting; Testosterone buccal film: Dry mouth, gingival swelling, lip swelling, mouth ulceration, stomatitis[Ref]

The majority of gum-related adverse events were transient.[Ref]

Very common (10% or more): Testosterone topical: Application site pruritus (up to 37%), application site blistering (12%)Common (1% to 10%): Injection site pain, injection site discomfort, injection site pruritus, erythema, injection site hematoma, injection site irritation, injection site inflammation; injection site reaction; Topical testosterone: Application site erythema, application site warmth, application site irritation, application site vesicles, application site exfoliation, application site burning, application site induration, bullae at application site, mechanical irritation at application site, rash at application site, contamination of application sitePostmarketing reports: Injection site abscess, procedural pain, application site swelling (topical testosterone)[Ref]

Common (1% to 10%): Hot flush, hypertensionUncommon (0.1% to 1%): Cardiovascular disorderFrequency not reported: Venous thromboembolismPostmarketing reports: Angina pectoris, cardiac arrest, cardiac failure, coronary artery disease, coronary artery occlusion, myocardial infarction, tachycardia, cerebral infarction, cerebrovascular accident, circulatory collapse, deep venous thrombosis, syncope, thromboembolism, thrombosis, venous insufficiency, stroke[Ref]

Common (1% to 10%): Abnormal prostate examination, benign prostate hyperplasia (BPH), ejaculation disorder, prostatitisUncommon (0.1% to 1%): Prostate induration, prostatic disorder, testicular pain, decreased urine flow, urinary retention, urinary tract disorder, nocturia, dysuriaRare (less than 0.1%): Micturition disorders, epididymitis, bladder irritability, impotence, inhibition of testicular function and testicular atrophyFrequency not reported: Oligospermia, priapism, benign prostatic hyperplasia (prostatic growth to eugonadal state), excessive frequency and duration of erections; Pediatrics: Precocious sexual development, an increased frequency of erections, phallic enlargementPostmarketing reports: Prostate infection, calculus urinary, dysuria, hematuria, urinary tract disorder, pollakiuria[Ref]

Common (1% to 10%): Polycythemia, hematocrit increasedUncommon (0.1% to 1%): Increased red blood cell count, increased hemoglobin, prolonged activated partial thromboplastin time, prolonged prothrombin timeFrequency not reported: Blood and lymphatic system disorders, suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapyPostmarketing reports: Thrombocytopenia, anemia[Ref]

Common (1% to 10%): Weight increased, appetite increased, fluid retention (sodium, chloride, water, potassium, calcium, and inorganic phosphates)Uncommon (0.1% to 1%): Increased glycosylated hemoglobin, hypercholesterolemia, increased triglycerideFrequency not reported: Abnormal lipids (decrease in serum LDL, HDL, and triglycerides), metabolism and nutrition disorders, hypercalcemiaPostmarketing reports: Hypoglycemia, diabetes mellitus, fluid retention, hyperlipidemia, hypertriglyceridemia, blood glucose increased[Ref]

Common (1% to 10%): Back pain, hemarthrosis (testosterone topical)Uncommon (0.1% to 1%): Arthralgia, pain in extremity, muscle spasm, muscle strain, myalgia, musculoskeletal stiffness, increased creatine phosphokinaseFrequency not reported: Pediatrics: Premature epiphyseal closure, increased bone formationPostmarketing reports: Musculoskeletal chest pain, musculoskeletal pain, myalgia, osteopenia, osteoporosis, systemic lupus erythematosus[Ref]

Common (1% to 10%): Headache, vertigo (topical testosterone)Uncommon (0.1% to 1%): Migraine, tremor, dizzinessFrequency not reported: Nervousness, paresthesiaPostmarketing reports: Cerebrovascular insufficiency, reversible ischemic neurological deficiency, transient ischemic attack, amnesia[Ref]

Common (1% to 10%): Prostatic specific antigen (PSA) increased, prostate cancerUncommon (0.1% to 1%): Prostatic intraepithelial neoplasiaRare (less than 0.1%): Neoplasms benign, malignant, and unspecified (including cysts and polyps)[Ref]

Common (1% to 10%): Fatigue, hyperhidrosis; chills, body pain, smell disorderUncommon (0.1% to 1%): Breast induration, breast pain, sensitive nipples, gynecomastia, increased estradiol, increased testosterone, asthenia, night sweats Rare (less than 0.1%): Fever, malaiseFrequency not reported: EdemaPostmarketing reports: Sudden hearing loss, tinnitus, Influenza like illness[Ref]

Common (1% to 10%): Irritability, insomnia, mood swings, aggression,Uncommon (0.1% to 1%): Depression, emotional disorder, restlessness, increased libido, decreased libidoFrequency not reported: Hostility, anxietyPostmarketing reports: Korsakoff's psychosis nonalcoholic, male orgasmic disorder, restlessness, sleep disorder[Ref]

Common (1% to 10%): Sinusitis, nasopharyngitis, upper respiratory tract infection, bronchitisUncommon (0.1% to 1%): Cough, dyspnea, snoring, dysphoniaRare (less than 0.1%): Pulmonary microembolism (POME) (cough, dyspnea, malaise, hyperhidrosis, chest pain, dizziness, paresthesia, or syncope) caused by oily solutionsFrequency not reported: Sleep apneaPostmarketing reports: Chest pain, asthma, chronic obstructive pulmonary disease, hyperventilation, obstructive airway disorder, pharyngeal edema, pharyngolaryngeal pain, pulmonary embolism, respiratory distress, rhinitis, sleep apnea syndrome[Ref]

Signs and symptoms of pulmonary microemboli may occur during or immediately after the injections and are reversible.[Ref]

Uncommon (0.1% to 1%): Abnormal LFT, increased ASTRare (less than 0.1%): Abnormal hepatic functionFrequency not reported: Jaundice, benign liver tumor, malignant liver tumor, liver enlargement, peliosis hepatitisPostmarketing reports: ALT increased, AST increased, bilirubin increased, transaminases increased, gamma-glutamyltransferase increased[Ref]

Uncommon (0.1% to 1%): Hypersensitivity reactionsFrequency not reported: Anaphylactic reactionsPostmarketing reports: Anaphylactic shock[Ref]

Uncommon (0.1% to 1%): Testosterone topical: Lacrimation increasedPostmarketing reports: Testosterone topical: Intraocular pressure increased, vitreous detachment[Ref]

Postmarketing reports: Nephrolithiasis, renal colic, renal pain[Ref]

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2. "Product Information. AndroGel (testosterone)." Unimed Pharmaceuticals, Buffalo Grove, IL.

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Testosterone Enanthate (testosterone)." West-Ward Pharmaceutical Corporation, Eatontown, NJ.

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6. "Product Information. Axiron (testosterone)." Lilly, Eli and Company, Indianapolis, IN.

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8. "Product Information. Aveed (testosterone)." Endo Pharmaceuticals Solutions Inc, Malvern, PA.

9. "Product Information. Testim (testosterone)." A-S Medication Solutions, Chicago, IL.

10. "Product Information. Androderm (testosterone topical)." SmithKline Beecham, Philadelphia, PA.

11. "Product Information. Depo-Testosterone (testosterone)." Pfizer U.S. Pharmaceuticals Group, New York, NY.

12. Bates GW, Cornwell CE "Iatrogenic causes of hirsutism." Clin Obstet Gynecol 34 (1991): 848-51

13. Dobs AS, Meikle AW, Arver S, Sanders SW, Caramelli KE, Mazer NA "Pharmacokinetics, efficacy, and safety of a permeation-enhanced testosterone transdermal system in comparison with bi-weekly injections of testosterone enanthate for the treatment of hypogonadal men." J Clin Endocrinol Metab 84 (1999): 3469-78

14. O'Driscoll JB, August PJ "Exacerbation of psoriasis precipitated by an oestradiol-testosterone implant." Clin Exp Dermatol 15 (1990): 68-9

15. Fyrand O, Fiskaadal HJ, Trygstad O "Acne in pubertal boys undergoing treatment with androgens." Acta Derm Venereol 72 (1992): 148-9

16. Traupe H, von Muhlendahl KE, Bramswig J, Happle R "Acne of the fulminans type following testosterone therapy in three excessively tall boys." Arch Dermatol 124 (1988): 414-7

17. Wu FC, Farley TM, Peregoudov A, Waites GM "Effects of testosterone enanthate in normal men: experience from a multicenter contraceptive efficacy study. World Health Organizatio Task Force on Methods for the Regulation of Male Fertility." Fertil Steril 65 (1996): 626-36

18. Bennett NJ "A burn-like lesion caused by a testosterone transdermal system." Burns 24 (1998): 478-80

19. Buckley DA, Wilkinson SM, Higgins EM "Contact allergy to a testosterone patch." Contact Dermatitis 39 (1998): 91-2

20. DeSanctis V, Vullo C, Urso L, Rigolin F, Cavallini A, Caramelli K, Daugherty C, Mazer N "Clinical experience using the Androderm (R) testosterone transdermal system in hypogonadal adolescents and young men with beta-thalassemia major." J Pediatr Endocrinol Metab 11 (1998): 891-900

21. Cefalu WT, Pardridge WM, Premachandra BN "Hepatic bioavailability of thyroxine and testosterone in familial dysalbuminemic hyperthyroxinemia." J Clin Endocrinol Metab 61 (1985): 783-6

22. Matsumoto AM "Effects of chronic testosterone administration in normal men: safety and efficacy of high dosage testosterone and parallel dose-dependent suppression of luteinizing hormone, follicle-stimulating hormone, and sperm production." J Clin Endocrinol Metab 70 (1990): 282-7

23. Tripathy D, Shah P, Lakshmy R, Reddy KS "Effect of testosterone replacement on whole body glucose utilisation and other cardiovascular risk factors in males with idiopathi hypogonadotrophic hypogonadism." Horm Metab Res 30 (1998): 642-5

24. Becker U, Gluud C, Bennett P "The effect of oral testosterone on serum TBG levels in alcoholic cirrhotic men." Liver 8 (1988): 219-24

25. Ferrera PC, Putnam DL, Verdile VP "Anabolic steroid use as the possible precipitant of dilated cardiomyopathy." Cardiology 88 (1997): 218-20

26. Jackson JA, Waxman J, Spiekerman AM "Prostatic complications of testosterone replacement therapy." Arch Intern Med 149 (1989): 2365-6

27. Zelissen PM, Stricker BH "Severe priapism as a complication of testosterone substitution therapy." Am J Med 85 (1988): 273-4

28. Wang C, Leung A, Superlano L, Steiner B, Swerdloff RS "Oligozoospermia induced by exogenous testosterone is associated with normal functioning residual spermatozoa." Fertil Steril 68 (1997): 149-53

29. Endres W, Shin YS, Rieth M, Block T, Schmiedt E, Knorr D "Priapism in Fabry's disease during testosterone treatment." Klin Wochenschr 65 (1987): 925

30. Parker LU, Bergfeld WF "Virilization secondary to topical testosterone." Cleve Clin J Med 58 (1991): 43-6

31. Zhang GY, Gu YQ, Wang XH, Cui YG, Bremner WJ "A clinical trial of injectable testosterone undecanoate as a potential male contraceptive in normal Chinese men." J Clin Endocrinol Metab 84 (1999): 3642-7

32. Anderson FH, Francis RM, Faulkner K "Androgen supplementation in eugonadal men with osteoporosis-effects of 6 months of treatment on bone mineral density and cardiovascula risk factors." Bone 18 (1996): 171-7

33. Bhasin S, Storer TW, Javanbakht M, et al. "Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels." JAMA 283 (2000): 763-70

34. Bagatell CJ, Heiman JR, Matsumoto AM, Rivier JE, Bremner WJ "Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men." J Clin Endocrinol Metab 79 (1994): 561-7

35. Lajarin F, Zaragoza R, Tovar I, Martinezhernandez P "Evolution of serum lipids in two male bodybuilders using anabolic steroids." Clin Chem 42 (1996): 970-2

36. Zmuda JM, Thompson PD, Dickenson R, Bausserman LL "Testosterone decreases lipoprotein(a) in men." Am J Cardiol 77 (1996): 1244

37. Stannard JP, Bucknell AL "Rupture of the triceps tendon associated with steroid injections." Am J Sports Med 21 (1993): 482-5

38. Pollard M "Tumorigenic effect of testosterone." Lancet 336 (1990): 1518

39. Uzych L "Anabolic-androgenic steroids and psychiatric-related effects: a review." Can J Psychiatry 37 (1992): 23-8

40. Nuzzo JL, Manz HJ, Maxted WC "Peliosis hepatis after long-term androgen therapy." Urology 25 (1985): 518-9

41. Carrasco D, Prieto M, Pallardo L, Moll JL, Cruz JM, Munoz C, Berenguer J "Multiple hepatic adenomas after long-term therapy with testosterone enanthate. Review of the literature." J Hepatol 1 (1985): 573-8

42. Yu MW, Chen CJ "Elevated serum testosterone levels and risk of hepatocellular carcinoma." Cancer Res 53 (1993): 790-4

43. Falk H, Thomas LB, Popper H, Ishak KG "Hepatic angiosarcoma associated with androgenic-anabolic steroids." Lancet 2 (1979): 1120-3

Some side effects of testosterone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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Testosterone Side Effects in Detail - Drugs.com

What is Testosterone?Testosterone is the hormone produced by the testicles. It is responsible for the proper development of male sexual characteristics. It helps promote the circulation of blood, and is responsible for the maintenance of muscle bulk. Without an adequate testosterone level there can be important psychological affects such as loss of libido, reduced brain and intellectual activity and mood changes.What causes the Andropause? As all men age there is a gradual decline in the level of testosterone. This natural decline starts after 30 and continues throughout life. By the age of 40, testosterone levels drop by 1% every year. Many men however can experience a lack of testosterone production sufficient to result in significant symptoms. This will apply to approximately 50% of men by age 55. Damaged testicles or disease will affect testosterone production as will long-term stress, smoking and excessive alcohol consumption. In 60% of cases no cause can be identified and hereditary factors are implicated. Are there any health issues associated with the Andropause? Low levels of testosterone may result in an increase in tummy and chest fat, a decline in the amount of muscle in the body and decline in strength. Low levels can also lead to Brittle bones, (osteoporosis) which may lead to hip and spinal fractures. In addition the bone marrow is less active and produces less haemoglobin and red blood cells to transport oxygen around the body.

A consultation is required and blood tests will be necessary. The blood tests include an examination for prostate cancer, as this is a contraindication to testosterone treatment. Any suspicion of prostate cancer may require further investigations. The aim of therapy is to return the blood testosterone level in the bloodstream to the normal range for the man's age. This is achieved by using bio-identical testosterone cream that is rubbed onto the skin daily.

IF YOU THINK YOU MIGHT HAVE LOW TESTOSTERONE, check out our quick online self assessment test.

More here:
Testosterone Replacement Therapy - Men's Health Clinic NZ

Understand the potential risks and consider alternatives before boosting your hormones indefinitely.

Millions of American men use a prescription testosterone gel or injection to restore normal levels of the manly hormone. The ongoing pharmaceutical marketing blitz promises that treating "low T" this way can make men feel more alert, energetic, mentally sharp, and sexually functional. However, legitimate safety concerns linger. For example, some older men on testosterone could face higher cardiac risks.

"Because of the marketing, men have been flooded with information about the potential benefit of fixing low testosterone, but not with the potential costs," says Dr. Carl Pallais, an endocrinologist and assistant professor of medicine at Harvard Medical School. "Men should be much more mindful of the possible long-term complications."

MIND Depression Reduced self-confidence Difficulty concentrating Disturbed sleep

BODY Declining muscle and bone mass Increased body fat Fatigue Swollen or tender breasts Flushing or hot flashes

SEXUAL FUNCTION Lower sex drive Fewer spontaneous erections Difficulty sustaining erections

Images: Thinkstock

A loophole in FDA regulations allows pharmaceutical marketers to urge men to talk to their doctors if they have certain "possible signs" of testosterone deficiency. "Virtually everybody asks about this now because the direct-to-consumer marketing is so aggressive," says Dr. Michael O'Leary, a urologist at Harvard-affiliated Brigham and Women's Hospital. "Tons of men who would never have asked me about it before started to do so when they saw ads that say 'Do you feel tired?'"

Just being tired isn't enough to get a testosterone prescription. "General fatigue and malaise is pretty far down my list," Dr. O'Leary says. "But if they have significant symptoms, they'll need to have a lab test. In most men the testosterone level is normal."

If a man's testosterone looks below the normal range, there is a good chance he could end up on hormone supplementsoften indefinitely. "There is a bit of a testosterone trap," Dr. Pallais says. "Men get started on testosterone replacement and they feel better, but then it's hard to come off of it. On treatment, the body stops making testosterone. Men can often feel a big difference when they stop therapy because their body's testosterone production has not yet recovered."

This wouldn't matter so much if we were sure that long-term hormone therapy is safe, but some experts worry that low-T therapy is exposing men to small risks that could add up to harm over time.

A relatively small number of men experience immediate side effects of testosterone supplementation, such as acne, disturbed breathing while sleeping, breast swelling or tenderness, or swelling in the ankles. Doctors also watch out for high red blood cell counts, which could increase the risk of clotting.

The evidence for long-term risks is mixed. Some studies have found that men on testosterone have fewer cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. Other studies have found a higher cardiac risk. For example, in 2010, researchers halted the Testosterone in Older Men study when early results showed that men on hormone treatments had noticeably more heart problems. "In older men, theoretical cardiac side effects become a little more immediate," Dr. Pallais says.

Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. As with the hypothetical cardiac risks, the evidence is mixed. But because prostate cancer is so common, doctors tend to be leery of prescribing testosterone to men who may be at risk.

"Like any treatment, there is risk," Dr. O'Leary says. "I would not give it to a man who is being treated for active prostate cancer, but it's pretty safe under careful supervision for those who need it."

For the time being, the long-term risks of testosterone therapy are "known unknowns." It offers men who feel lousy a chance to feel better, but that quick fix could distract attention from unknown long-term hazards. "I can't tell you for certain that this raises the risk of heart problems and prostate cancer, or that it doesn't," Dr. Pallais says. "We need a large study with multiple thousands of people followed for many years to figure it out."

So, keep risks in mind when considering testosterone therapy. "I frequently discourage it, particularly if the man has borderline levels," Dr. Pallais says.

These steps can help you feel more energetic today without drugs or dietary supplements:

Pace yourself: Spread out activities throughout the day.

Take a walk: It gives you a lift when you feel pooped out.

Snack smart: Have a snack with fiber and some protein between meals.

A large, definitive trial for hormone treatment of men is still to come. Until then, here is how to take a cautious approach to testosterone therapy.

Have you considered other reasons why you may be experiencing fatigue, low sex drive, and other symptoms attributable to low testosterone? For example, do you eat a balanced, nutritious diet? Do you exercise regularly? Do you sleep well? Address these factors before turning to hormone therapy.

If your sex life is not what it used to be, have you ruled out relationship or psychological issues that could be contributing?

If erectile dysfunction has caused you to suspect "low T" as the culprit, consider that cardiovascular disease can also cause erectile dysfunction.

Inaccurate or misinterpreted test results can either falsely diagnose or miss a case of testosterone deficiency. Your testosterone level should be measured between 7 am and 10 am, when it's at its peak. Confirm a low reading with a second test on a different day. It may require multiple measurements and careful interpretation to establish bioavailable testosterone, or the amount of the hormone that is able to have effects on the body. Consider getting a second opinion from an endocrinologist.

After starting therapy, follow-up with your physician periodically to have testosterone checks and other lab tests to make sure the therapy is not causing any problems with your prostate or blood chemistry.

Approach testosterone therapy with caution if you are at high risk for prostate cancer; have severe urinary symptoms from prostate enlargement; or have diagnosed heart disease, a previous heart attack, or multiple risk factors for heart problems.

Ask your doctor to explain the various side effects for the differentformulations of testosterone, such as gels, patches, and injections. Know what to look for if something goes wrong.

Testosterone therapy is not a fountain of youth. There is no proof that it will restore you to the level of physical fitness or sexual function of your youth, make you live longer, prevent heart disease or prostate cancer, or improve your memory or mental sharpness. Do not seek therapy with these expectations in mind.

If erectile function has been a problem, testosterone therapy might not fix it. In fact, it might increase your sex drive but not allow you to act on it. You may also need medication or other therapy for difficulty getting or maintaining erections.

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Is testosterone therapy safe? Take a breath before you ...

Testosterone Booster vs. Replacement

Testosterone, while mostly thought of as the hormone that makes a male a man, there is more to its functions in the body. Testosterone is not only primarily responsible for the sex drive, it is also important for mans vitality, strength, agility and vigor. It is also important to women because it plays an intrinsic role in keeping them sexually active.

Summarily, it is often referred to as the elixir of youth, thanks to its ability to keep men feeling young and agile. Unfortunately, once you it the big 30, your testosterone levels start to decrease. This decline often results in depression, low libido, erectile dysfunction, difficulty in achieving orgasms, low ejaculation volume, impaired memory and poor concentration.

The combination of all these conditions is called hypogonadism. When this happens for a prolonged period of time and they are diagnosed with the LOW-T condition, most men start looking for solutions in the form of testosterone boosters and replacement therapy. Which brings us to the important question: Whats the difference between testosterone replacement therapy and testosterone boosters?

This is important because there is a clear difference between the two even though many often use the terms interchangeably.

Simply put, testosterone boosters are supplements that are used to help bodybuilders build more mass and strength. Also known as an alternative to anabolic steroids, this is nowhere near the real deal. T-Boosters as they are popularly called, are meant to help you do more and achieve more results whilst working out and training. Think of it as a steroid of sorts.

Only this time, its uncharted waters as evidenced by the lack of approval by the FDA. There are no known proofs of it being able to help boost your testosterone levels apart from the usual testosterone boost you get from high intensity workouts- no matter how much thats used in the products sales copies. All reports about testosterone boosters being able to help increase motivation seems unfounded and lacking in authenticity.

On the other hand, testosterone therapy is known for its effectiveness at boosting and increasing the testosterone levels of people who are suffering from hypogonadism. Its often known to help them become more agile, more enthusiastic, increases, their sense of well-being and sex drive, whilst eliminating problems like erectile dysfunction, depression, fatigue and poor concentration. There are quite a few testosterone replacement therapies.

Usually, talking to your doctor about how you feel will help them decide on what therapy method would best suit you. Many patients have recorded tremendous improvements on their testosterone levels through the impact of exogenous testosterone treatment regimens. Testosterone replacement therapies often include the use of testosterone patches, testosterone, topical gels and testosterone injections.

Men who have used testosterone gels often notice an increase in their testosterone levels to about 500-600 ng/dl (the normal testosterone levels) as against the 300 ng/dl levels observed in men diagnosed with Low-T. While there are testosterone pills, their use is largely discouraged because of their significant impact in liver toxicity.

Testosterone patches can be either scrotal or non-scrotal and are also known to be effective in increasing the bodys T-levels. The downside to using this however is that it tends to irritate the skin. Testosterone gels are known to be significantly absorbed by the skin and have a near-instant absorption rate which lasts throughout the day. And theres also the buccal testosterone which is known to produce even better results than the patches when applied to the gums. The side effects of that however often include bitter taste in the mouth and some irritation to the gums.

As you can see, testosterone boosters are clearly not the same thing as testosterone replacement. So, if you feel that you be might suffering from Low-T, consult with your doctors and let them place you on the necessary testosterone replacement therapies instead of self-medicating with testosterone boosters.

Sources:

http://www.harvardprostateknowledge.org/a-harvard-expert-shares-his-thoughts-on-testosterone-replacement-therapy

http://www.webmd.com/erectile-dysfunction/guide/testosterone-replacement-therapy

http://www.health.harvard.edu/press_releases/is-testosterone-replacement-therapy-safe

http://www.webmd.com/men/guide/testosterone-replacement-therapy-is-it-right-for-you0

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Dont Be Fooled: The Difference Between Testosterone ...

The most effective delivery method for Testosterone Replacement Therapy (or TRT) is Testosterone injections. Testosterone Replacement Therapy typically requires weekly Testosterone injections and ancillary medications, where necessary. These may include medications which allow the testes to continue its natural production of testosterone while on TRT, and an Aromatase Inhibitor, typically in pill form, to suppress the bodys conversion of Testosterone to Estrogen.

Every man has his own unique set of circumstances and must be treated as an individual. Therefore, EHormonesMD managed physicians perform physical examinations on every patient, in addition to using a combination of comprehensive, diagnostic lab work, feedback from the patient himself, as well as medical history and symptomology to determine the patients individual Testosterone Therapy regimen. However, it is important to note that not every adult male will be a candidate for Testosterone Replacement Therapy. This is why its very important that you speak with a doctor who specializes in treating Low Testosterone in adult men.

Ask yourself if you suffer from one or more of the following:

Original post:
Testosterone Replacement Therapy - Ehormones

New Jersey Testosterone Therapy Clinics.In a multi-institutional study to understand the effects of testosterone treatment in men age 30 and older, researchers found improved sexual function, walking ability and mood. The study, conducted by 12 institutions including Baylor College of Medicine in partnership with the National Institute on Anti-Aging, appears today in the New England Journal of Medicine.

This is the largest to date and most rigorously conducted trial evaluating the benefits of testosterone Injections in older men with low testosterone levels, said Dr. Glenn Cunningham, distinguished professor emeritus in the department of medicine endocrinology at Baylor. Cunningham served as the principal investigator for the Baylor site and as a member of the steering committee for the trials. However, our trial is not large enough nor did it last long enough to determine potential risks of testosterone replacement Therapy.

As men age, their testosterone levels decrease, and previous studies on the effects of testosterone Therapy treatment in older men have been inconclusive. Researchers studied testosterone treatment in men 65 and older whose testosterone levels were low due to age alone. The 790 men enrolled in the trials were randomized into two groups one applying a testosterone gel daily and the other applying a placebo gel daily.

For this study, researchers conducted a coordinated group of seven trials and have now published the results of the first three: sexual function, physical function, and vitality. They found that testosterone Injections treatment increased the blood testosterone level to mid-normal for young men and improved all aspects of sexual function, including sexual activity, sexual desire and the ability to get an erection. When researchers evaluated only men enrolled in the physical function trial, the treatment did not significantly improve distance walked in six minutes, but when all men in the trials were considered, it did show an increase in distance walked. The study also showed that the treatment improved mood and depressive symptoms.

Researchers concluded that a larger and longer study needed to be conducted to understand the risks of the treatment.

The Perelman School of Medicine at the University of Pennsylvania was the coordinating site for the study. Other institutions taking part in the study included Albert Einstein College of Medicine, Brigham and Womens Hospital, Harbor-UCLA Medical Center, University of Alabama at Birmingham, Northwestern University Feinberg School of Medicine, Puget Sound Health Care System, University of California at San Diego School of Medicine, University of Florida School of Medicine, University of Minnesota School of Medicine, University of Pittsburgh School of Public Health, and Yale School of Medicine.

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