Indy’s first ever Black Vegan Fest to highlight healthy eating, Black-owned businesses – The Indianapolis Star

If youre a vegan newbie, there are a variety of things you may have thought to be 'safe' but they do contain animal-derived ingredients. Buzz60

After traveling the country to highlight Black vegan chefs and restaurants on her blog, Another Vegan Journey, LLC, Quiana Quarles was left wondering how to best represent the Black vegan chefs in her own backyard.

Her answer was Black Vegan Fest Indy.

Since February, Quarles has been planning the event, the first of its kind in Indianapolis. But organizers had to postpone the in-person event until July 24, 2021. Instead, the event moves online as the Black Vegan Fest Indy Digital Experience on Saturday. The event page already has 1,400 responses on Facebook.

We wanted to see peoples reactions when they taste the food, to see them engage in person, said social media coordinator Dinah Allen. But this is the next best thing.

Black Vegan Fest Indy founder Quiana Quarles poses with a festival T-shirt. The festival will take place in an online format this Saturday.(Photo: William Thomas)

The event will include live performances, including a DJ and a local spoken word artist. The rest of the afternoon will consist of a yoga session, a talk by family physician Tameka Jonesand cooking demonstrations, including one from featured chef Cul de Sac Poe from Indys the Cul De Sac Kitchen. The event will also provide coloring pages centered around vegetables native to different African countries, recipes and collections of items from vendors.

In addition to Black chefs, Quarles said a main focus of the event is highlighting local Black-owned businesses, including Black Mama Vegan, Arm Kandy LLC, Smooves Indy, Brewer Bakesand Sip & Share Wines.

Black Vegan Fest Indy founder Quiana Quarles shows off her biomineral wrap from Cul de Sac Kitchen. Cul de Sac Poe from Indys vegan restaurant the Cul De Sac Kitchen will be a featured chef at the festival.(Photo: Quiana Quarles)

Quarles hopes the space will celebrate Black-owned businesses, as well as Black artists, chefs and physicians.

We have to support each other as a community, she said. And we can do that by being conscious about our choices in businesses we support. I want people to know that these businesses are here.

While the event centers around spreading awareness about the health benefits of veganism and how delicious vegan food can be, it is more than that, Quarles said. She saw a need for a festival like this in Indianapolis because of food deserts around the city that disproportionately affect Black populations.

Black Vegan Fest Indy founder Quiana Quarles shows off her meal from Smoove's Indy. The vegan, plant-based restaurant is one of the Black-owned businesses that will be featured at Black Vegan Fest Indy.(Photo: Quiana Quarles)

In 2019, one fifth of Indys population or 208,000 residents lived in a food desert, according to a report by SAVI, a program in the Polis Center at Indiana University-Purdue University Indianapolis. That number is a 10% increase from 2016 and includes 2,000 more people than in 2018.

Our communities are filled more with fast food places than grocery stores, she said. And the grocery stores we do have arent well stocked. If you move toward the more well-to-do suburbs, the Krogers are stocked with great, fresh food.

Quarles said the festival will promote the idea that everyone deserves access to healthy foods, regardless of race and zip code, and prompt discussions on the barriers that prevent some groups from accessing such healthy foods.

I just want to see my people live healthier, live longer, she said. Everybody deserves to be healthy.

Contact Pulliam Fellow Christine Fernando at cfernando@gannett.com.

Read or Share this story: https://www.indystar.com/story/entertainment/dining/restaurants/2020/07/24/black-vegan-fest-indy-moves-online-highlights-black-owned-businesses/5492867002/

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Indy's first ever Black Vegan Fest to highlight healthy eating, Black-owned businesses - The Indianapolis Star

How to lose visceral fat – four of the very best exercises that target your belly fat – Express

Visceral fat is more commonly known as belly fat, and it tends to wrap around your internal organs.

It's considered a serious health problem to be carrying too much visceral fat.

That's because the fat cells produce inflammatory markers and hormones, that increases the risk of chronic diseases.

One of the more effective ways to lose your visceral fat is to regularly do certain exercises, it's been claimed.

READ MORE: How to get rid of visceral fat: Six major changes you need to make

"Its every weight loss enthusiasts dream to zap belly fat but, far from pure vanity, theres actually a reason why having a lot of fat in the abdominal region can be dangerous," said the dietitian.

She wrote on the My Fitness Pal blog: "Because of its proximity to the liver, visceral fat is usually the easier fat to burn. Its the less risky subcutaneous fat that likes to stick around.

"Unfortunately, you cant forcefully spot reduce fat around your belly no matter how many crunches you do. The next best thing is to live a healthy lifestyle.

"Visceral fat responds well to regular endurance exercises, such as running, biking, rowing, swimming, that elevate your heart rate. As your body uses fat to fuel exercise, itll start using up your visceral stores."

Meanwhile, you could also lose your visceral fat by adopting a low-carb diet, it's been claimed.

Low-carb diet plans aim to limit the amount of carbohydrates you're eating, including potatoes, bread, and pasta.

Swapping your refined carbs for nutrient-rich carbohydrates - including fruit and vegetables - helps to reduce your visceral fat.

Without refined carbohydrates, your body begins to burn fat for fuel, which is ideal for those wanting to lose belly fat.

Visceral fat starts to cause health problems straight away.

It increases your risk of developing serious, long-term life-threatening medical conditions, including heart disease, high blood pressure, Alzheimer's disease, diabetes, and strokes.

You should consider speaking to a doctor if your waist is more than 40 inches for men, or 35 inches for women.

Your GP will discuss the health risks of belly fat, as well as some lifestyle changes to get rid of it.

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How to lose visceral fat - four of the very best exercises that target your belly fat - Express

Now comes real hard part: Getting fans back into the game – Atlanta Journal Constitution

So, let me get this straight: You can gather with others observing the proper coronavirus cautions we are told to watch a televised version of a game while having a beer, eating something incompatible with a healthy lifestyle and generally milling about. But you cant do the very same thing just an achingly few yards away, inside the venue where the action is?

Its as if the two surviving Beatles were playing a gig, but were only allowed to watch A Hard Days Night on a bedsheet hung in the arenas parking lot.

Oddly enough, some of the best ballpark-style atmospheres occur in actual ballparks. You cant beat it for the realism.

Credit a tribal nature for this need to join and share the experience of cheering on the home team. The urge is strong.

And not banging on the Batterys businesses here for trying to stay solvent in hard times. Theyre doing what they can.

Just not sure what the rules are for the communal watching of our sports. Everything is so confusing. But you already knew that.

The Braves still hold the hope of one day opening Truist Park to a limited number of fans before this truncated season is done. Maybe this all will make some sense again. Welcome to Freddie Freeman Autographed Mask Night.

In the meantime, its OK to sit six feet away from a stranger in a bar, spitting vile oaths at some bad turn in the televised game from beneath your mask. But not OK to sit an aisle away from a like-minded fan in a fractionally occupied ballpark.

The Falcons have said they could foresee playing their home games in front of between 10,000 and 20,000 customers inside the 70,000-seat Mercedes Benz stadium if/when the NFL season happens. Through a blind draw, each season ticket holder would have access to a game or two among the eight home dates. If the virus numbers dont recede, welcome to a new and edgy variation of Russian Roulette.

The colleges certainly will be taking notes and doing some hard math on the risk-reward of trying to slip in a few of the big-money donors to watch the proceedings in person. They will be slightly more animated than cardboard cutouts, but a good deal more grateful. As reduced attendance puts seats at even more of a premium, college students become even more of a nuisance at a college game.

In such a world I cant help but wonder what happens to the secondary ticket market? Does the scarcity of the ticket rocket the resale value skyward? Or does the uncertainty about the health risks flatten prices? I send a lot of time worrying about the well-being of ticket profiteers.

Psst, hey, Bud, I got two for the Vandy game in a nice secluded end zone section for $600 per. Ill throw in the hand sanitizer for free.

And here you thought getting athletes back on the field was difficult. Getting real, live fans back in the game and with them, bringing back honest emotion over the canned commotion is going to be far more complicated and confusing.

About the Author

Steve Hummer writes sports features and columns for The Atlanta Journal-Constitution. He covers a wide range of sports and topics.

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Now comes real hard part: Getting fans back into the game - Atlanta Journal Constitution

Stocks making the biggest moves in the premarket: Verizon, American Express, Honeywell, Mattel & more – CNBC

Take a look at some of the biggest movers in the premarket:

Verizon (VZ) Verizon reported quarterly profit of $1.18 per share, 3 cents a share above estimates. Revenue beat forecasts as well. Verizon said it experienced a negative impact from Covid-19, which hurt wireless service and ad spending revenue.

American Express (AXP) American Express reported quarterly earnings of 29 cents per share, compared to estimates of an 11 cents per share loss. Revenue came in below estimates, however. The company saidspending volumes hit a low point in April, followed by a gradual rebound in May and June.

Honeywell (HON) Honeywell beat estimates by 5 cents a share, with quarterly earnings of $1.26 per share. Revenue was above estimates as well. The industrial conglomerate said it will face ongoing sales challenges in certain segments due to the pandemic, including aerospace and oil and gas.

Schlumberger (SLB) The oilfield services company reported a quarterly profit of 5 cents per share, compared with the consensus estimate of a penny a share loss. Revenue was in line with Wall Street expectations. As with others in the industry, major Schlumberger customers reduced their activity as oil prices slumped.

Goldman Sachs (GS) Goldman reached a $3.9 billion settlement with Malaysia in the 1MDB case, in which Goldman had been accused of misleading investors during bond sales to raise money for the sovereign investment fund.

Intel (INTC) Intel reported quarterly earnings of $1.23 per share, 12 cents a share above estimates. The chipmaker's revenue was above forecasts as well. Intel signaled further delays in a new generation of superfast chips, weighing on its stock and boosting that of rival Advanced Micro Devices (AMD), which already has a "7nm" chip on the market.

Mattel (MAT) Mattel lost 26 cents per share for its latest quarter, smaller than the 34 cents a share loss that Wall Street was expecting. Revenue was also better than expected, with retail sales of Mattel's flagship Barbie brand up 35%.

E*Trade (ETFC) E*Trade came in 12 cents a share above estimates, with quarterly earnings of 88 cents per share. The online brokerage's revenue was above estimates as well, helped by heavier trading during a period of stock market volatility.

Walt Disney (DIS) Disney again delayed the release of its "Mulan" movie, while also pushing back new installments of "Star Wars" and "Avatar." At the same time, the Paramount unit of ViacomCBS (VIAC) pushed back the release date of its "Top Gun" sequel, "Top Gun: Maverick."

Skechers (SKX) Skechers lost 44 cents per share for its latest quarter, smaller than the 66 cents a share loss that analysts had been expecting. The shoe maker's revenue also came in ahead of estimates, even though CEO Robert Greenberg said like most businesses, the company had "never faced a more challenging time."

Boston Beer (SAM) Boston Beer more than doubled the consensus estimate of $2.43 per share, with quarterly earnings of $4.88 per share for the second quarter. The Sam Adams beer maker's revenue topped forecasts as well, helped by a surge in demand for home consumption of its products even as bars and restaurants were shut down.

AstraZeneca (AZN) The drugmaker received Food and Drug Administration approval for its drug to treat patients with chronic obstructive pulmonary disease (COPD), the third leading cause of death globally.

Edwards Lifesciences (EW) Edwards doubled consensus estimates with quarterly earnings of 34 cents per share, while the medical products maker's revenue was also well above Wall Street forecasts. Sales were initially depressed during the quarter due to focus on the pandemic, but Edwards said procedure volumes did improve during May and June.

Skyworks Solutions (SWKS) The chipmaker reported quarterly profit of $1.25 per share, 13 cents a share above estimates. Revenue beat Wall Street forecasts as well, helped by growth in 5G-related products. Skyworks also announced a 14% dividend increase to 50 cents per share.

Under Armour (UAA) Deutsche Bank issued a "Catalyst Call Buy" on the athletic apparel maker's stock, saying earnings will beat consensus as healthy lifestyle trends take hold and as stores reopen.

Originally posted here:
Stocks making the biggest moves in the premarket: Verizon, American Express, Honeywell, Mattel & more - CNBC

Health and wellbeing: join our new weekly challenge on the road to a fun and fit life – The Northern Echo

Few, if any people will have complete physical, mental and social wellbeing all the time. Trevor Smith, a senior member of the Chartered Institute for the Management of Sport and Physical Activity, will join us every week to talk about mental health and wellbeing

Of course, health and wellbeing is a huge subject, so the aim of the article is simply to give some useful insight, to share my experiences and if youd like to, you can even join a friendly challenge that you can share on social media.

This week, after a short introduction I would like to touch on a topic that is a real passion of mine, physical activity. I have been lucky that physical activity has always been a big part of my life. From being part of a local junior football team during my school years, to the 5am runs on the assault course during military basic training. This was followed by the seemingly never-ending circuit training sessions during the rest of my military service. Upon leaving the service I made it into a successful career working in some of the most luxurious five-star hotels across the Middle East. Having now returned to my native North East again doing something I love, supporting primary schools to develop the physical literacy of all their pupils through active learning which will help children enjoy a healthy, fun and fit life. This all came about with the arrival of my daughter which got me wondering about her physical activity journey and what that will look like, something we will cover in more depth over the coming weeks.

Being active is good for your health and wellbeing in many ways

The lockdown restrictions have given us all the opportunity to get more physically active, I wonder how many have? I certainly do not mean that in a preachy kind of way, everyone knows the benefits of regular physical activity and healthy lifestyle choices, its our motivation and confidence that are major factors that could be obstacles in whether we participate.

During the lockdown restrictions, it has been great to see the sense of community responsibility in regard to protecting the NHS with most people observing the strict social distancing rules.

We can all continue to protect the NHS in other ways even when the lockdown restrictions have been completely lifted. Did you know the gov.uk website shows the most recent spending figures prior to Covid-19 for the direct cost to the NHS for overweight and obesity-related ill-health was an estimated 6.1 billion in a single year?

We can all take some form of physical activity, I am not suggesting for one moment that you should immediately go out and try to run a 10K, but if you can great do it. It must be right for your circumstances and it can seem an overwhelming task to begin with. However, moderate physical activity can be a brisk walk, 30 minutes of gardening or even doing household chores incorporating some silky dance moves. My wife will testify that I love doing the washing up while dancing along with the music of George Benson playing in the background. Well, now that I have shared that little secret then maybe I can persuade you to share some of your physical activities.

This weeks challenge

This week I would like you to take part in some form of physical activity, it can be anything at all, something you already do regularly or something you are trying for the first time. Share your photos and comments with us and tag us on Twitter at @TheNorthernEcho and @TSmith_PE

If you are looking for some inspiration for activities to do with the family, try the Stay Active resources which are completely free at http://www.premier-education.com/stay-active/ - check out all the activity cards and videos under the Physical section.

Be inspired to join Trevor's weekly challenge

If you would like to let me know how you have increased your normal levels of activity over this lockdown period, ask a question or suggest a topic that you would like me to cover in the coming weeks, you can contact me at tsmith@premier-education.com

Good luck

Trevor works at Premier Education. He is a senior member of the Chartered Institute for the Management of Sport and Physical Activity (CIMSPA) and a member of the International Physical Literacy Association (IPLA).

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Health and wellbeing: join our new weekly challenge on the road to a fun and fit life - The Northern Echo

Nanomedicine – an overview | ScienceDirect Topics

17.8 Commentary on Hurdles in Clinical Translation of Various Nanotechnology Products

Research regarding nanoconstructs development in the cancer treatment field has witnessed a noticeable increase after discovery of the EPR effect. However, the number of anticancer drugs that actually reached the market was considered extremely low, as out of 200,000 anticancer drugs only 15 made it by 2017 (Greish et al., 2018). The reasons why most of the nanomedicines cannot even reach the market are the hardship or inability to maintain detailed characterization of these products, unsuccessful manufacturing on large scales, and issues in their safety and efficacy. These hurdles require many developmental processes to overcome them including a precise understanding of every component and all the possible interactions between them, determination of key characteristics to understand in which possible ways they affect performance, and the extent of it. If key characteristics can be replicated under manufacturing conditions (scaling up), the efficacy of targeting at the site of action and their stability and sterility can be enhanced and/or assessed (Desai, 2012). The majority of these hurdles are summarized in Table 17.5 (Tinkle et al., 2014).

Table 17.5. Major Hurdles That Face the Commercialization of Nanomedicine

Lack of standard nano nomenclature: imprecise definition for nanomedicines

Currently used compounds/components for nanodrug synthesis often pose problems for large-scale good manufacturing (cGMP) production

Lack of precise control over nanoparticle manufacturing parameters and control assays

Lack of quality control: issues pertaining to separation of undesired nanostructures (byproducts, catalysts, starting materials) during manufacturing

Reproducibility issues: control of particle size distribution and mass

Scalability complexities: enhancing the production rate to increase yield

High fabrication costs

Lack of rational preclinical characterization strategies via multiple techniques

Biocompatibility, biodistribution and toxicity issues: lack of knowledge regarding the interaction between nanoparticles and biosurfaces/tissues

Consumer confidence: the publics general reluctance to embrace innovative medical technologies without clearer safety or regulatory guidelines

The relative scarcity of venture funds

Ethical issues and societal issues are hyped up by the media

Big Pharmas continued reluctance to seriously invest in nanomedicine

Patent review delays, patent thickets, and issuance of invalid patents by the US Patent and Trademark Office

Regulatory uncertainty and confusion due to baby steps undertaken by US Food and Drug Administration: a lack of clear regulatory/safety guidelines

One of the major concerns related to NPs is their potential incompatibility and toxicity. Studies showed that inhaling NPs can cause pulmonary inflammation as well as inducing endothelial dysfunction that might lead to further complications in the cardiovascular system. A study for evaluation of iron oxide toxicity showed that monocyte-mediated dissolution and phagocytosis of the NPs have caused severe endothelial toxicity by initiating oxidative stress. Nanomaterials used in oral DDS have been shown to accumulate in hepatic cells, which might induce the immune response and eventually cause permanent damage to the liver. The accumulation of NPs in cells has been found to cause cancer by transforming cells into the tumorous state (Jain et al., 2018; Riehemann et al., 2009). Thus, handling these nanosystems requires special equipment and caution, which increases the cost of the production process and requires further investigations of the safety of nanomaterials to have a better understanding and optimize safety during manufacturing (Hammed et al., 2016). Production of NPs in the laboratory often requires complex, multistep synthesis processes to yield the nanomaterials with the required properties. Aside from the complexity of the process, controlling conditions such as temperature and concentrations precisely is significant to achieve homogeneity of NPs in terms of desired characteristics. However, retaining temperature and concentration in large systems is harder to achieve resulting in NPs with different characteristics (Gomez et al., 2014).

NPs tend to aggregate forming clusters with several microns in size. Aggregation of NPs alters their characteristics such as reactivity, transport, toxicity, and risk in the environment. Dissolution reduces when aggregation occurs due to the decrease in available surface area that will eventually reduce the activity of NPs. For example, dechlorination rate of CT (carbon tetrachloride) by magnetite NPs has shown to decrease when aggregation of the NPs increases resulting in an inverse relationship between dechlorination rate of carbon tetrachloride and aggregation of magnetite NPs (Hotze et al., 2010; Hou and Jafvert, 2009).

All these requirements are extremely important because the majority of the nanomedicines have failed to reach the commercialization step even though their efficacy in animal models was considerably high. Due consideration must be given regarding the several difficulties such as their low targeting, low safety, low efficacy, heterogeneity of disease between individuals, inability to scale-up successfully, and unavailability in determining a convenient characterization methods (Agrahari and Agrahari, 2018; Hare et al., 2017; Kaur et al., 2014). These hurdles that face the research process of accelerated translation are summarized in Fig. 17.8 (Satalkar et al., 2016).

Figure 17.8. Major issues that face accelerated translation process of nanoparticles.

Therefore, more understanding in all aspects of nanomedicine production, characterization, and clinical processes must be fulfilled to control and improve the development processes, and increase the efficacy of the translational methods. Other significant hurdles hindering clinical translation are the insignificant incentives regarding technology transfer, as well as socioeconomic uncertainties along with the safety problems faced. In the majority of cases, consideration of commercialization aspects in early stages of development is hardly even considered thus eliminating the market-oriented development (Rsslein et al., 2017).

Nanomedicines face tough, challenging concerns when it comes to determining the applicable analytical tests in terms of chemical, physical, or biological characterization. This is mainly achieved due to their complex nature in comparison with other pharmaceutical products. Hence, there is a need for more complex and advanced levels of testing to ensure a full accurate characterization of nanomedicine products. Quantification of each component of nanomedicine is considered essential alongside the identification and evaluation of interactions between them. For more possibility in achieving successful manufacturing processes with reproducibility, these products should be investigated and understood more during the early developmental stages to identify their key characteristics. The challenges for nanomedicine during scale-up and manufacturing are considered relatively unique because other pharmaceutical manufacturing processes systems are not three-dimensional multicomponent in nature on the nanometer scale. Therefore, a certain series of obstacles in the scale-up process is required. To reach the desired safety, pharmacokinetic and pharmacodynamic parameters to produce the therapeutic effect are needed. These are further determined by the proper selections of the essential components, determination of the critical manufacturing steps, and key characteristics identification. Several methods of orthogonal analysis are essential for in-process quality controls of nanoparticle products and any deviations from key parameters could result in a significant negative impact on both the safety and efficacy of nanomedicines (Desai, 2012).

Each step in the manufacturing process of NPs must be understood extensively with the need of experienced technicians. The development process also requires more enhancements in both complexity and cost. Inadequate data regarding scaling-up processes of nanomedicine products is a major concern in the commercialization step as there are only a few reports supporting scaling-up developments. Many formulation methods have been developed for manufacturing nanomedicine products. The most common methods are nanoprecipitation and emulsion-based approaches. Generally, formulations are prepared either by precipitating the dissolved molecules (bottom-up method) or by reducing the size of larger drug particles (top-down method). Removal of the solvent in the bottom-up method is not an easy process and it cannot be controlled well either, thus explaining why this method is less often applied in industrial manufacturing (Agrahari and Agrahari, 2018; Vauthier and Bouchemal, 2009). Investments in innovative projects face several issues with the major one being the knowledge that should be obtained from the innovation. Its confidentiality is easily breached when a company uses that knowledge as it cannot prevent other companies from using it. Thus, investors are not attracted to this type of project because the total return on the investment cannot be easily appropriated (Morigi et al., 2012).

The complexities in formulating nanoproducts on large scales are due to the inability of optimization of formulation processes and achieving reproducibility. Whereas formulation steps including size reduction, homogenization, centrifugation, sonication, solvent evaporation, lyophilization, extrusion, and sterilization can be easily optimized on small-scales, its still a challenging process on large-scales. Accordingly, variations between batches cannot be controlled sufficiently thereby limiting the possibility of nanomedicine to get through commercial translation (Anselmo et al., 2017; Desai, 2012).

Another problem is that even slight changes in either the formulation or the manufacturing process can have a significant effect on the nanomedicine physiochemical properties (crystallinity, size, surface charge, release profile), which will ultimately influence the therapeutic outcome. Most of the pharmaceutical industrial facilities cannot manufacture nanomedicines because of the lack of the right equipment for the process. As nanomedicine manufacturing usually involves the use of organic solvents, the ability to correctly process and handle nanoproducts is crucial to control their safety and sterility (Anselmo et al., 2017; Desai, 2012; Kaur et al., 2014). These steps require an expensive and complicated equipment, well-trained staff, and precise control to get the required product in the right quality (Desai, 2012; Kaur et al., 2014; Ragelle et al., 2017).

To date, only 58 nanoformulations are approved based on their clinical efficacy but only a quarter of them are meant for cancer treatment. Majority of the nanoformulations could not even be reproduced successfully due to several factors including the study design, overall analysis, protocols, data collection, and the quality and purity of materials used. Besides, the poor establishment of the correlation and prediction of safety and efficacy of the nanomedicine on patients hinders the successful DDS. Targeting and drug accumulation of anticancer drugs in the site of action is considered relatively poor in mouse models. Many nanoformulations were faced with failure in different clinical trial phases. Some of them got approved but then withdrawn from the market such as peginesatide. Unfortunately, the increased failures will most probably affect the development movement in the pharmaceutical industry (Greish et al., 2018).

At the present time, regulatory agencies such as the FDA and EMEA are examining every new nanomedicine on a product-by-product basis. They are considered a unique category due to the fact that there are no true standards in their examination process (Desai, 2012). Two of the major regulatory issues that emerged at the start of nanomedicine is the lack of scientific experts in the FDA and the difficulty in classifying the product (Morigi et al., 2012). The unique characteristics of nanomedicines are directly related to their regulation hurdles, which is the same as other pharmaceutical systems such as liposomes and polymeric systems (Sainz et al., 2015).

Researchers keep investigating nanomedicines when attached to prodrugs, drugs, tracking entities, and targeting molecules. Development of robust methods and assays in quality control of nanomedicines are required for more effective monitoring and characterizations. Also, estimation of their overall performance in releasing drugs, binding to proteins, and the specificity in cellular uptake must be considered (Sainz et al., 2015; Tinkle et al., 2014).

Nanomedicine products are both complex and diverse requiring explanation of challenges to have a clear definition and an effective regulation. The lack of regulatory guidelines for these products hinders their clinical potential. Drug regulatory authorities must keep up with the rapid pace of the knowledge and technological development as they play a major role translating nanomedicines towards the market. The European Medicines Agency (EMEA) and the FDA have different requirements in evaluating new nanomedicines as well as different definitions regarding nanomedicine. Agreeing on specific regulatory procedures internationally is very important to ease the translational researches of nanomedicines. Also, better long-term monitoring of toxicity should be achieved by prolonging postmarketing surveillance especially for a patient with chronic diseases (Sainz et al., 2015; Tinkle et al., 2014).

Nanomedicines just like any other pharmaceutical formulations must offer higher value to patients to become commercially successful, and have better efficacy and safety. New nanomedicine products follow the same steps in clinical trials as other drugs. It starts with preclinical tests, then be submitted to get the IND (investigational new drug) approval and following that it enters the three stages of clinical trials, one after another to evaluate safety and efficacy of the new drug (Agrahari and Agrahari, 2018).

In recent years, toxicities caused by nanomedicines have drawn attention and been recognized to be unique to nanoparticulate systems. Hence, a minimum set of measurements for the nanoparticle like surface charge, size, and solubility are monitored so as to predict the possible toxicity of NPs. Besides, NPs can stimulate the immune system by acting as an antigen. Immunogenicity is mainly affected by the size of the nanoparticle, its surface characteristics, hydrophobicity, charge, and solubility. Hematologic safety concerns have also been observed such as hemolysis and thrombogenicity (Desai, 2012).

In vivo and in vitro studies provide the proper characterization of the interactions between the product and the biological system. The problem is that the data attained from current toxicity tests are not from clinical trials and it cannot always be extrapolated to humans. Monolayers of cell cultures are currently used to characterize immunogenicity, drug release, cellular uptake, and toxicity. However, the cellular uptake process of nanoformulations is majorly influenced by physicochemical characteristics. Thus, 3D cell systems will probably provide better outcomes (Gupta et al., 2016). More caution should be given when handling any nanosized powder due to the ability of such particles to penetrate the skin and because it can also show pulmonary toxicity (Agrahari and Hiremath, 2017; Nel et al., 2006).

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Nanomedicine - an overview | ScienceDirect Topics

Impact of COVID-19 on Global Testosterone Replacement Therapy Market with Covid-19 Effect Analysis | likewise Industry is Booming Globaly with Key…

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Years Considered to Estimate the Market Size:History Year: 2015-2019Base Year: 2019Estimated Year: 2020Forecast Year: 2020-2026

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Impact of COVID-19 on Global Testosterone Replacement Therapy Market with Covid-19 Effect Analysis | likewise Industry is Booming Globaly with Key...

Global Testosterone Replacement Therapy Market Size, Revenue Expectation, Market Dynamics, Growth Status, Global Trends Evaluation, Covid 19 Analysis…

Global Testosterone Replacement Therapy Market Report is an objective and comprehensive study of the current state expected at the major drivers, market strategies, and key vendors growth. The study also includes the important achievements of the market, Research & development and regional growth of the leading competitors operating in the market.

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Leading players of Testosterone Replacement Therapy Market:

AbbVie, Endo International, Eli lilly, Pfizer, Actavis (Allergan), Bayer, Novartis, Teva, Mylan, Upsher-Smith, Ferring Pharmaceuticals, Kyowa Kirin, Acerus Pharmaceuticals

Global Testosterone Replacement Therapy Geographical Segmentation Includes:

The research report includes an exploration of the competitive landscape present in the global Testosterone Replacement Therapy Market. It includes an impost of the current and future trends that players can invest in. Likewise, it also includes an estimation of the business outlooks of the players and explains the nature of the competition.

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Global Testosterone Replacement Therapy Market Segmentation

Global Testosterone Replacement Therapy Market Segmentation: By Types

GelsInjectionsPatchesOther

Global Testosterone Replacement Therapy Market Segmentation: By Applications

HospitalsClinicsOthers

The plus point of this research study is that it includes the impact ofCOVID-19to the Testosterone Replacement Therapy market. The data summarized within this research study includes forecast from 2019 to 2024. COVID-19 has significantly impacted each and every market on the global platform. If you have any specific requirement then Please get in touch with us. Our Expert team will provide as per report customized to your requirement.

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Important Features of the report:

Detailed analysis of the Testosterone Replacement Therapy market

Changing market dynamics of the trade

Comprehensive market segmentation

Historical, present and expected market size in terms of volume and value

Current business trends and developments

Testosterone Replacement Therapy Market Modest landscape of the market

Plans of key players and product offerings

A neutral view towards market performance

Reasons for buying this report:

It compromises an analysis of moving competitive scenario.

For making up-to-date decisions in the businesses, it offers analytical data with strategic planning methodologies.

It offers a Six-year assessment of the Global Testosterone Replacement Therapy

It supports in sympathetic the major key product segments.

It offers the regional analysis of the Global Testosterone Replacement Therapy Market along with the business profiles of several stakeholders.

It offers huge data about trending factors that will impact the progress of the Global Testosterone Replacement Therapy

Some Major TOC Points:

Chapter 1. Testosterone Replacement Therapy Market Report Overview

Chapter 2. Global Testosterone Replacement Therapy industry Growing Trends

Chapter 3. Market Share by Key vendors

Chapter 4. Testosterone Replacement Therapy Market Breakdown Data by Type and Application

Chapter 5. Testosterone Replacement Therapy Market by End Users/Application

Chapter 6. COVID-19 Outbreak: Testosterone Replacement Therapy Industry Impact

Chapter 7. Opportunity Analysis in Covid-19 Crisis

Chapter 9. Market Driving Factors

And Many More

Table of Content & Table Of Figures

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Global Testosterone Replacement Therapy Market Size, Revenue Expectation, Market Dynamics, Growth Status, Global Trends Evaluation, Covid 19 Analysis...

DeepMinds Protein Folding AI Is Going After Coronavirus

In late December last year, Dr. Li Wenliang began warning officials about a novel coronavirus in Wuhan, China, but was silenced by the police before tragically succumbing to the disease two months later. Meanwhile, almost simultaneously, a computer server halfway across the world started issuing worrying alerts of a potential new outbreak. The server runs software by BlueDot, a company based in San Francisco that uses AI to monitor infectious disease outbreaks for signs of early trouble.

Not enough people listened to either human expertise or AI. Then cases skyrocketed in Wuhan and spread across the world, and people had to take note.

Hindsight is 20/20, but it is remarkable that BlueDot and other machine learning-based services are beginning to catch early signs of infectious disease outbreaksalmost within the same time frame as health experts, if just for COVID-19. We often hear about AI as the next second coming of healthcare, where it can catch cases early, accelerate drug development, and personalize treatment. Yet COVID-19 is the first global pandemic to ever hold healthcare AIs feet to the flame in a global, serious, and urgent real-world test case. In a head-to-head race, can AI actually accelerate new anti-virals or vaccines for COVID-19, something the world has never previously seen? Or will traditional biotech measures excel, in turn unveiling that AIs hype massively outstrips reality?

MIT Technology Review recently reported an excellent piece that comprehensively looks at how AIat its current ability levelcan help us predict, diagnose, and treat novel viral threats. Im on board with the general idea: AIs potential is enormous.

Yet for now, dont look to AI to help tackle COVID-19; its simply not ready.

That said, it is enormously helpful to see how major machine learning companies are utilizing or repositioning their technologies for tackling the crisis. People often critique AI tested in toy cases, or standardized, limited datasets that may have limited significance in the real world. With companies working on COVID-19, thats no longer the case.

Ready, player, go? Heres how one major AI player in healthtech, DeepMind, is trying to knee-cap COVID-19.

The promise of AI for accelerating medical drug discovery is almost a universally supported idea. One caveat: so far, though new drugs have been discovered using AI, no AI-based drug candidate has made it through the approval process (yet), or even demonstrated that the tech makes the whole process faster to market (yet).

In very broad strokes, AI could be enormously helpful for initial drug discovery in two main ways: one, screening through millions of chemical compounds for potential drugs in simulation tests, far faster than any human expert; two, identifying targets that new drugs can latch onto, either to reduce their impact (making people less sick), or to slow their spread among people.

For COVID-19, DeepMind is focusing on the second route. Known mostly for its algorithms that beat human players at Go, DOTA, and other games, DeepMind has nevertheless been working directly on solutions for drug discovery. Their secret sauce? AlphaFold, a deep learning system that tries to predict protein structures accurately when no similar proteins exist.

Stay with me. How a protein looks in 3D is essential for developing new drugs, especially for new viruses. COVID-19, for example, has really spikey proteins that jut out from its surface. Normally, human cells dont carethey wont let the virus inside. But COVID-19s spikey proteins also harbor a Trojan Horse that activates it in certain cells with a complementary component. Lung cells have an abundance of these factors, which is why theyre susceptible to invasion.

Bottom line: if a drug is going to fit into a protein like a key into a lock to trigger a whole cascade of nasty reactions, then the first step is to figure out the structure of the lock. Thats what DeepMinds AlphaFold is doing.

Thanks to a surge of global collaboration, China released the genomic blueprint of the COVID-19 virus in open-access databases, whereas others have posted online the structure of some of its proteinseither determined by experiments or through computational modeling. DeepMind is taking these data to the next level by focusing on a few understudied but potentially important proteins that could become drug or vaccine targets using machine learning.

Protein folding has been a decades-long, fundamental problem in biochemistry and drug discovery. Almost all of our existing drugs grab onto certain proteins to work, so identifying protein structure is akin to surveying the enemy landscape and figuring out best attack point simultaneously. The problem is the genetic code doesnt translate to how proteins look. When it comes to a new virus, without predicting protein structures were basically fighting viruses and diseases as if they were the Invisible Man.

Traditional methods use high-tech microscopes, freezing proteins into crystal-looking entities, and other strange and expensive ways to understand their structure. Under the scope, a protein is basically a chain of chemical letters that wrap around itself into intricate structureskinda like how your headphones always tangle into inconceivable structures while youre sleeping. For DeepMind and other protein-folding efforts, the key is to predictand then find methods to decipher drug targets fromthose structures.

AlphaFold stands out as a union of decades of deep learning progress, but guided by expertise from protein structure databases in the public domain. In a nutshell, AlphaFold uses genome sequences (available for COVID-19 and relatively easy to get) to predict the properties of resulting proteins that actually do the work, by looking at the distance of each letter or component that makes up a certain protein. It doesnt predict specific sequences with special powerssuch as those that bind to a cellbut offers a quick police sketch of the virus perp in sight.

Theres no doubt that AlphaFold is new to the protein-folding game. Even DeepMind itself stresses that these structure predictions have not been experimentally verified, but could galvanize efforts at making anti-virals and/or vaccines. For now, its difficult to judge how much AlphaFold will contribute to the pandemic, if at all. But by automating a critical aspect of drug discovery, its also en route to becoming a much larger player in the next epidemic.

Of note: all of this would not be possible without public, open-source databases of protein structures (like UniProt and the Protein Data Bank) thats been building for decades. DeepMinds release, posted with open access, has been lauded by fellow scientists as a way of giving back to the community.

Chinas long-time Google surrogate and AI behemoth, Baidu, is using an algorithm to predict the structure of another important biomolecule, mRNA. mRNA shuttles information from the genome to protein factories, so shoot the mRNA messenger, then the viral proteins are never born. Similarly, AI could one day potentially predict epidemics and how a virus changes over timebut it will only help if theres enough trust to listen to the models.

Various AI companies are also making a play towards efficient diagnosticsidentifying COVID-19 signs in medical scansor other measures to support at-risk and overworked medical frontline heroes. The problem is that with any new outbreak, we dont have enough data to train an AI, which means that they will struggle to find subtle differences in imperfect medical scans, at least for now.

So, is AI our savior? Not in this pandemic. Similar to the 2003 SARS outbreak, the best response is something that has existed for centuries: social distancing. As I mentioned previously, before COVID-19 exploded into a pandemic, science was ready to provide answers for COVID-19 as long as governments were also ready to respond. And because AI is based on scientific data and helping otherwise difficult efforts, machine learning is rapidly learning to do the same.

But perhaps ironically, COVID-19 is exposing both the best and weakest parts of AI in our current society for healthcare: great models that in theory should work, solid predictions that can be tested, but not without any recommendations without a heavy dose of skepticism. COVID-19 presents a brutal test case for AI in healthcare.

But for now, the toughest case is that of government management and what we do in response.

Note: To learn more about the Covid-19 pandemic, tune into Singularity Universitys free virtual summit: Covid-19: The State & Future of Pandemics.

Image Credit: Vektor Kunst from Pixabay

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DeepMinds Protein Folding AI Is Going After Coronavirus

GOLO Deepens Its Commitment to Healthy Living with Innovative Products Designed to Support Weight-Loss, Immunity, and a Healthy Lifestyle – Yahoo…

GOLO, a weight loss and wellness solution company, plans to launch more products designed to improve overall health and vitality, along with a focused reach to lower income households and communities in the effort to promote healthy lifestyles for the whole family.

NEWARK, Del., July 23, 2020 /PRNewswire-PRWeb/ -- The GOLO brand was developed by a team of expert scientists and medical doctors to find a natural and effective weight loss solution. A recent study by the CDC indicates that nearly 7 out of 10 Americans are considered overweight or obese. If this trend is not reversed, the emotional and economic toll on families and society is likely to be immeasurable. Over the past four years, GOLO has revolutionized weight loss through a dedicated approach to Insulin Resistance. Insulin is one of the most important hormones in your body because it directly affects metabolism, weight gain, aging and overall health. Insulin's performance is affected by unbalanced diets which increase glucose levels and spike insulin levels causing excess glucose to be stored as fat. Unhealthy insulin levels lead to Insulin Resistance, pre-diabetes and Type 2 diabetes, and other serious health conditions including heart disease and Alzheimer's.

To resolve this common issue, the GOLO team created their Release supplement, a patented, natural, plant and mineral based dietary supplement that is made in the USA. The Release supplement targets dangerous visceral fat that is driven by hormones, mainly insulin. The Release supplement balances the hormones that regulate fat and carbohydrate metabolism, control stress, cravings and hunger between meals, and overall metabolic health. The Release supplement supports healthy blood glucose metabolism, controls sugar cravings, balances the key weight loss hormones, increases energy, reduces stress, and supports immunity. Release is paired with the GOLO for Life plan a simple eating guide to balanced meals and good nutrition for anyone.

Based on past successes, GOLO plans to launch more products designed to improve overall health and vitality, along with a focused reach to lower income households and communities in the effort to promote healthy lifestyles for the whole family. These new products will include:

GOLO for Wellness, GOLO for Immunity, GOLO for Weight Loss, GOLO for LIFE.

About GOLO: GOLO is committed to providing individuals with the knowledge of health and wellness, and the power to take back control of their weight and their lives. The GOLO for Life plan is an all-natural, plant-based supplement and meal plan, designed to address the root cause of weight gain. The GOLO products provide a safe solution to weight- loss and wellness while helping individuals transition to a healthier and sustainable lifestyle. The developers of GOLO, LLC include a team of dedicated doctors, pharmacists and researchers. GOLO has reached over a million people worldwide who now have a chance at healthy, sustainable and affordable weight loss. For more information about the GOLO for Life plan, visit http://www.golo.com or call 800-730-4656 (GOLO).

###

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GOLO Deepens Its Commitment to Healthy Living with Innovative Products Designed to Support Weight-Loss, Immunity, and a Healthy Lifestyle - Yahoo...

Bioinformatics Platforms Market: Year 2017-2027 and its detail analysis by focusing on top key players like Illumina, Qiagen, ID Business Solutions,…

Bioinformatics Platforms Market 2020 Global Industry research report explores analysis of historical data along with size, share, growth, demand, revenue and forecast of the global Bioinformatics Platforms and estimates the future trend of market on the basis of this detailed study. The study shares market performance both in terms of volume and revenue and this factor which is useful & helpful to the business.

Bioinformatics is one of the branch of information technology which deals with the development of software solutions in order to process biological data. Some of the applications included in the bioinformatics research includes, genome annotation, modeling, molecular folding, expression profiling, and gene/protein prediction. The emergence and advancements in bioinformatics are associated with the computerized programming which are specially designed to handle large volumes of DNAs, RNAs, proteins, and metabolites.

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The report provides a detailed overview of the industry including both qualitative and quantitative information. It provides an overview and forecast of the global Bioinformatics Platforms market based on the deployment type and application. It also provides market size and forecast till 2027 for overall Bioinformatics Platforms market with respect to five major regions, namely; North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America (SAM). The market by each region is later sub-segmented by respective countries and segments. The report covers the analysis and forecast of 18 countries globally along with the current trend and opportunities prevailing in the region.

The study conducts SWOT analysis to evaluate strengths and weaknesses of the key players in the Bioinformatics Platforms market. Further, the report conducts an intricate examination of drivers and restraints operating in the market. The report also evaluates the trends observed in the parent market, along with the macro-economic indicators, prevailing factors, and market appeal according to different segments. The report also predicts the influence of different industry aspects on the Bioinformatics Platforms market segments and regions.

Bioinformatics Platforms Market Company Profiles

The List of Companies Illumina Inc., Qiagen, ID Business Solutions,, Dassault Systems, Agilent Technologies, Genologics Life Sciences Software Inc., Sophia Genetics, DNASTAR, Wuxi NextCODE,BGI

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Most important type of Bioinformatics Platforms covered in this report are:

Based on end user/application, this report focuses on the status and outlook for major applications:

The research provides answers to the following key questions:

Our reports will help clients solve the following issues:

Insecurity about the future

Our research and insights help our clients anticipate upcoming revenue compartments and growth ranges. This will help our clients invest or divest their assets.

Understanding market opinions:

It is extremely vital to have an impartial understanding of market opinions for a strategy. Our insights provide a keen view on the market sentiment. We keep this reconnaissance by engaging with Key Opinion Leaders of a value chain of each industry we track.

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Our research ranks investment centers of market by considering their future demands, returns, and profit margins. Our clients can focus on most prominent investment centers by procuring our market research.

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Our research and insights help our clients identify compatible business partners.

Table Of Content

1.INTRODUCTION

2. KEY TAKEAWAYS3. RESEARCH METHODOLOGY4. BIOINFORMATICS PLATFORMS LANDSCAPE

5. BIOINFORMATICS PLATFORMS KEY MARKET DYNAMICS

6. BIOINFORMATICS PLATFORMS GLOBAL MARKET ANALYSIS

7. BIOINFORMATICS PLATFORMS REVENUE AND FORECASTS TO 2027 PLATFORM TYPE

8. BIOINFORMATICS PLATFORMS REVENUE AND FORECASTS TO 2027 APPLICATION

9. BIOINFORMATICS PLATFORMS REVENUE AND FORECASTS TO 2027 END USER

10. BIOINFORMATICS PLATFORMS REVENUE AND FORECASTS TO 2027 GEOGRAPHICAL ANALYSIS

11. INDUSTRY LANDSCAPE

12. BIOINFORMATICS PLATFORMS, KEY COMPANY PROFILES

13. APPENDIX

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Bioinformatics Platforms Market: Year 2017-2027 and its detail analysis by focusing on top key players like Illumina, Qiagen, ID Business Solutions,...

Healthy living practices in families and child health: 5-year follow-up of Taiwan Birth Cohort Study – DocWire News

This article was originally published here

BMJ Open. 2020 Jul 21;10(7):e033613. doi: 10.1136/bmjopen-2019-033613.

ABSTRACT

OBJECTIVES: We have previously developed the Child Healthy Living Practices in Family (CHLPF) Index and found that the CHLPF Index was concurrently associated with the health of children at age 3. In this follow-up study, we aimed to examine whether healthy living practices in family at age 3 predicted health of children at school age.

DESIGN AND SETTING: Data came from the Taiwan Birth Cohort Study designed to assess the development and health of 24 200 children born in 2005.

PARTICIPANTS: A total of 18 553 cohort members whose mothers or primary caregivers had completed 6-month, 3-year, 5-year and 8-year surveys were included for analysis, representing a response rate of 87.3%.

OUTCOME MEASURES: A multiple logistic regression model was used to test the relationship between mother-rated childrens health at age 8 and the CHLPF Index level, after controlling for sex, birth outcomes, family structure, parental education, residential area, family income and mother-rated childs health at age 3.

RESULTS: The percentage of mother-rated good health at age 8 was 79.7%. Compared with the low CHLPF level, the adjusted OR of mother-rated good health was 1.38 (95% CI 1.19 to 1.60), 1.21 (95% CI 1.10 to 1.35) and 1.17 (95% CI 1.07 to 1.29), respectively, for high, high-low and mid-low CHLPF levels. Moreover, the prevalence of mother-rated good health at age 8 with high-level CHLPF Index in the low-income group was similar to that of the high-income group (83.72% vs 84.18%); the prevalence with low-level CHLPF Index in the low-income group was much lower than that of the high-income group (70.21% vs 78.98%).

CONCLUSIONS: Our study underscores that high level of healthy living practices in early childhood is positively associated with good health at school age, particularly for children from disadvantaged families.

PMID:32699124 | DOI:10.1136/bmjopen-2019-033613

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Healthy living practices in families and child health: 5-year follow-up of Taiwan Birth Cohort Study - DocWire News

MiraBurst, the world’s largest producer of miracle berry products, is dedicated to helping people reduce their intake of added sugars and sweeteners…

MiraBurst-Freeze-Dried-Miracle-Berries

Explore MiraBurstA healthy way to transform the taste of sour and acidic foods and drinks into something delectably sweet! Experience the sweet sensation with MiraBurst products and sweeten up your life while giving your health a boost with its many health benefits!

New York , July 23, 2020 (GLOBE NEWSWIRE) -- Miracle Berry: The Superfruit Every Diabetic Should Know About

MiraBurst Products and its Benefits

Consuming miracle berries is beneficial for ones health because the miracle berry is a superfruit, meaning it holds a robust nutritional value. The miracle berry is an all-natural, non-GMO fruit. It is the only fruit on the planet that has both taste-enhancing properties and several health benefits. As a taste enhancing berry, it allows for easy incorporation of healthy fruits, low sugar or sugar-free desserts as well as healthy smoothies and drinks into ones diet.

As a superfruit, themiracle fruitcontains antioxidants (polyphenols which consist of flavonoids and phenolics, vitamins A, C, E and others), essential amino acids, micronutrients and other phytonutrients. These phytonutrients are essential for healthy living. The phytonutrients work together to help manage blood sugar levels and help support the bodys natural immune system response. As a superfruit and a taste-modifier, miracle berries are a gamechanger for diabetics, pre-diabetics, as well as people looking to manage their weight.

Miracle berries are highly perishable fruits. In order to prolong the shelf life of the berries they have been converted into fast dissolving tablets without any additives or preservatives. This will allow consumers to recreate the same experience as eating the actual non-GMO and organic miracle berries. These tablets dissolve on the tongue and immediately create a unique taste-modifying experience. Consumers should allow the tablet to dissolve on the tongue for about 2-3 minutes to allow the active substance (miraculin) to properly activate the sweet receptors on the tongue before consuming the sour and acidic foods, fruits or drinks. The taste-modifying effect will last for up to 60 minutes after the tablet has fully dissolved on the tongue.

MiraBurst currently sells taste-enhancing miracle berry tablets that are fast-dissolving, have no additives or preservatives, and are made from 100% pure miracle berry powder. All MiraBurst miracle berries are grown under the most natural and organic environment in Ghana and cultivated by Fair Trade farmers. MiraBurst is the industry-leading source for all-natural, non-GMO, organic and pure miracle berry products.

Who Can Benefit from Miracle Berries?

MiraBurst miracle berry tablets are a gamechanger for everyone. MiraBurst tablets are perfect for parents looking to help their children prevent tooth decay due to sugary diets. Health-conscious eaters and people looking to lose weight can use these tablets to enjoy healthy fruits and fruit salads, foods, and smoothies and drinks in their diet while satisfying their sweet tooth. Chemotherapy patients can benefit from the berrys taste-enhancing properties because it can temporarily help mask chemotherapy-associated metallic taste.

MiraBurst is particularly beneficial for diabetics and borderline diabetics. MiraBurst can help diabetics and pre-diabetics improve their bodys sensitivity to their own insulin and manage blood sugar levels. Diabetes is a chronic disease that comes in four forms: Type 1, Type 2, Pre-Diabetes, and Gestational Diabetes. All types of diabetes result in high blood sugar levels. MiraBurst helps in the management of all types of diabetes and prediabetes.

MiraBurst pairs well with several diabetic superfoods recommended by the American Diabetes Association, such as unsweetened Greek yogurt, blueberries and other berries, grapefruit, and citrus fruits. MiraBurst miracle berries can make an unsweetened Greek yogurt parfait taste like ice cream. Fruit smoothies and green smoothies with lemon can taste sweet and even more delicious. Miracle berry can even make lemon water or apple cider vinegar with lemon water taste like a sugar-free lemonade, which is beneficial for diabetics since apple cider vinegar has been shown in clinical to improve the bodys sensitivity to insulin whilst lemon water help prevent blood sugar spikes after meals.

With regular use of MiraBurst tablets and an adoption of a low sugar diet as well as consumption of healthy fruits recommended by the American Diabetes Association, diabetics and borderline diabetics can manage their blood sugar levels and improve their overall health. Miracle berries can serve as diabetics trusted sidekick by helping reduce their sugar intake for all types of diabetics.

MiraBurst connects people affected by diabetes everywhere to an innovative means of reducing the added sugar in their daily diet. To learn more about MiraBurst and to try the miracle berry products yourself, visitwww.miraburst.comtoday!

About MiraBurst

MiraBurst was founded in 2014 by Dr. Emmanuel Asare with a mission to use the miracle berry to help solve the global problem of excessive sugar consumption and sugar addiction. Founded in response to the rise of diabetes and pre-diabetes (borderline diabetes), MiraBurst is dedicated to introducing consumers to the miracle berry to help cut down on consumption of sugar and sweeteners without sacrificing sweet taste.

Themiracle berry, known as the miracle fruit or Synsepalum dulcificum, is native to Ghana, West Africa. This superfruit has the ability to modify the taste of sour and acidic foods, fruits and drinks to sweet tasting without any added sugar or sweetener. This is due to the active substance in the pulp of the berry a glycoprotein called miraculin. Miraculin has a unique effect on the taste buds by supercharging the sweet receptors on the tongue. These taste-altering properties can make sour and acidic drinks, like lemon water with apple cider vinegar taste like a sugar-free lemonade.

Try it. Love it. Share it.#TasteTheSweetSensationFollow us on instagram@MiraBurst

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Phone: (516)597-5259

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Swimming is a great aerobic exercise that also promotes toning – Kingsport Times News

If your goals are endurance, improved mood, injury recovery, joint health, or upper-body strength, this is a must read.

According to Health Real Wellness magazine, about 40% of adults in the U.S. cant swim. If that number includes you, the Kingsport Aquatic Center offers lessons for adults and children.

Swimming is a great aerobic exercise thats also good for toning. This is because even the parts of your body that arent actively moving are supporting you against the resistance of the water.

Swimming is an excellent all-around activity because it:

Keeps your heart rate up but takes some of the impact stress off your body

Helps maintain a healthy weight, healthy heart and healthy lungs

Tones muscles and builds strength

Builds endurance, muscle strength, and cardiovascular fitness

The concepts of swimming and water activities have evolved greatly since the first written document on swimming by Nikolaus Wynmann in 1538, The Swimmer, or A Dialogue on the Art of Swimming and Joyful and Pleasant to Read.

At its inception, swimming was understood simply as moving in water first, in order to survive and then to compete. Today, the term clearly connotes swimming sports, and as such can be defined as an activity in which a person practices a regulated Olympic sport in order to move as fast as possible through the water thanks to the propulsive forces generated by arm, leg, and body movements overcoming the resistance the water presents to progress.

Swimming was part of the first modern Olympic games in 1896 in Athens. The skills of swimming have been adapted to different contexts and participants. The result is that there is now a great diversity of additional water activities: aquatic Olympic sports (water polo, diving, and synchronized swimming), non-Olympic sports and leisure activities.

The term aquatic activities covers all these plus swimming, and can be defined as motor activities performed in water for purposes that may be utilitarian, competitive, educational, therapeutic or recreational.

Detra Cleven, a master swimmer, said, I began swimming at a young age. My father wasnt into the tea parties or dolls, so he took me to the swimming pool after he got off work. I loved to splash around. However, I took some time off after college. I dabbled in the water, expanding to water aerobics, water walking, and general lap swimming. As my family, career, life happened, I would leave the water for a while and then find my way back.

Detra took swim lessons and loved it enough to start her competitive swimming journey at the age of 8 through high school and college. To this day, she still swims competitively with the Kingsport Aquatic Center Master Viperfish Team.

The downside to using swimming as an exercise is that finding space can be hard, but with the Kingsport Aquatic Center, the availability is more open in our area.

Detra expressed that she found swimming to be a place for her. With swimming being an individual sport with a team component, she loves the time to think, improve, and work on HERSELF. For Detra, swimming is both a mental and physical work in progress.

With Detras hard work and dedication, she competed in swim in the Tennessee and North Carolina area and eventually in the National Swim Meets across the U.S. This allowed her to meet and become friends with more people who love the water.

I have had success with Masters Swimming competitions, including being the national champion in the 50 butterfly and 200 individual medley.

I am also international masters champion in the 100 breaststroke, Detra added.

With that being said, Healthy Kingsport would like to ask you this question: If your doctor gave you a prescription that said it would improve your mood, improve energy, keep you mentally sharp, help you manage weight, reduce your risk of disease and injury, extend your life span, and cost little to nothing, youd probably say, Say what?

Healthy Kingsport would say, a prescription is immediately available and you dont need a doctor to write it for you. Its swimming!

Exercise Almanac is not finished. Next weeks article will discuss HIIT (high-intensity interval training): the benefits/downside and the good-to-knows.

Healthy Kingsport is a nonprofit organization dedicated to creating a community that actively embraces healthy living by promoting wellness, enhancing infrastructure and influencing policy. Aiesha Banks is the executive director of Healthy Kingsport. She can be reached at [emailprotected].

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Swimming is a great aerobic exercise that also promotes toning - Kingsport Times News

With new rules, use of masks reaches a tipping point – Greenfield Daily Reporter

HANCOCK COUNTY Face coverings have joined phones, keys, purses and wallets among the things people now must grab before heading out the door.

Health and government officials for weeks have encouraged their use to prevent the spread of COVID-19. Starting this week, the biggest stores in Hancock County began requiring shoppers to don them before coming inside. Next week, a statewide order goes into effect mandating their use in many situations.

For those who havent obtained any masks yet, theyre available to purchase unlike early in the pandemic and are easily made. A search on Amazon Thursday afternoon for COVID-19 face mask turned up 1,000 suggestions.

Gov. Eric Holcomb on Thursday, July 23, signed an executive order calling on Hoosiers to wear masks in all indoor spaces starting on Monday, July 27. The order also applies to any outdoor space where distancing is impossible. Also on Thursday, Indianas attorney general, Curtis Hill, issued an advisory opinion suggesting Holcomb had overstepped his authority to issue the order, but that opinion doesnt block it from taking effect, The Associated Press reported.

The requirement, coming amid a rising number of infections statewide, is designed to blunt transmission of the novel coronavirus as Hoosiers interact more freely, Holcomb said. According to state figures, up to 40% of people who harbor the virus may have no symptoms and so may be unwittingly spreading it to others, prolonging the outbreak and putting more people vulnerable to serious illness at risk.

But what type of mask should people be wearing starting on Monday?

According to guidance posted by the Indiana State Department of Health, cloth, non-medical face coverings are appropriate for people interacting in public. Medical-quality face coverings, such as N95 respirators, are considered critical supplies that should be used only by health-care workers. Surgical masks, the guidance says, should be reserved for health-care workers and first-responders who are in close contact with patients.

The Centers for Disease Control and Prevention says a cloth face covering may not protect the wearer, but it may keep them from spreading COVID-19 to others.

Masks should fit snugly; cover the bridge of the nose; and should tuck under the chin.

A face covering can take many forms. The Centers for Disease Control and Prevention has a YouTube video called How to Make Your Own Face Covering. In it, U.S. Surgeon General Dr. Jerome Adams walks through simple steps on how to make a covering by folding a scarf, bandanna, hand towel or T-shirt and using a couple rubber bands.

Hancock Health, meanwhile, recently donated more than 250,000 ear-loop face masks to the community.

Amanda Everidge, director of community health improvement for healthy365, an arm of Hancock Health that promotes healthy living, said the masks were donated to schools, cities and towns, local businesses, law enforcement, nonprofit organizations, churches, mental health providers and long-term care facilities.

Those in need of being connected to resources within the community throughout the COVID-19 pandemic are encouraged to reach out to the healthy365 Connection Center by calling 317-468-4231.

Meanwhile, This week, Walmart and Kohls, which have locations in Greenfield; and Meijer, which has stores in McCordsville and Cumberland, started requiring shoppers to wear masks. Kroger and Home Depot, which also have locations in Greenfield, started their shopper mask mandate on Wednesday.

Walmart has stationed heath ambassadors to remind those without masks of the new requirements and to work with those who dont have one.

Not far into the Greenfield store beyond its entrance stands a display of five-packs of washable masks selling for $7.50 each.

This week, signs outside the Walmart and Kroger stores reminded shoppers about the new requirements. Many shoppers were complying, judging from visits by a reporter.

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With new rules, use of masks reaches a tipping point - Greenfield Daily Reporter

Sharp Coronado Hospital Healthy Living Center Provides Onsite And At-Home Fitness – Coronado Eagle and Journal

In these past few months, we have all had to adjust to a new normal, most of which now happens in the home. Staying in shape, even pre-quarantine, was challenging for most people. The Sharp Coronado Hospital Healthy Living Center (HLC) recognizes that and is doing everything it can to keep its community members physically and mentally well.

For those who are able to leave the house, the HLC is providing outdoor personal trainer appointments. Employees are masked and socially distancing under a covered area. Located on the Soledad side of the hospital, outside, clients arent required to wear masks outdoors as long as social distancing is maintained.

Another option is to attend fitness classes from your very own home, powered by Zoom. There is a fully packed schedule with a variety of class types that cater to all ability levels. You can attend Yoga (in the chair or more advanced), Tai Chi, Qi Gong, Pilates, Cardio Circuit, Strength and Balance and a variety of meditation sessions. Most of the classes are 50 minutes and have music. All of the classes are taught by highly qualified instructors, Jenny Driessen, Cynthia Mendolia, George Montes and Noel Tarver whose passion is to motivate, educate and grow. Participants can pay per class or register for a monthly membership of unlimited virtual classes.

The at-home classes are not only a great way to stay in shape, but are also a way to connect to the outside world. The instructors offer real time feedback about form and ongoing encouragement to commit to your health. In the past few months, the HLC has accumulated a large number of dedicated followers and now friends. Register now to join the fun!

For more information, call the HLC front desk at 619-522-3798 or write to HLC@sharp.com

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How to Improve Gut Health – LIVESTRONG.COM

Getting in a workout can help boost the beneficial bacteria in your gut.

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The trillions of bacteria in your gut play vital roles in keeping your body and mind healthy and functioning properly.

But certain foods or lifestyle changes can cause gut problems and even lead to health issues. Here are 12 ways to improve gut health.

1. Aim for Diet Diversity

In a healthy person, the microbiome the bacterial environment in the GI tract is characterized by a very wide variety of gut bacteria (known as microbiota), according to a March 2016 article in Molecular Metabolism. In other words, the greater diversity of bacteria species, the better chance they'll contribute to certain health benefits. A decrease in the number of species, on the other hand, may lead to illness.

In order to get richness of microbiota species, you need richness in dietary choices. The more diverse your day-to-day menu is, the easier it will be for your microbiome to adapt to some curve balls you throw at it. Keep in mind that whole foods are the best options.

Speaking of adding some healthy foods to your menu, try going more plant-based your gut will thank you.

People following a vegan or vegetarian diet have a different gut microbiota than omnivores, per an October-December 2018 review in Tzu-Chi Medical Journal, possibly because vegan diets may deliver more fiber. When you up the fiber through plants, you're increasing the growth of more beneficial bacteria that provide anti-pathogenic and anti-inflammatory effects, as well as cardiovascular protection.

A plant-based diet is an effective way to not only support your gut microbiome, but also to maintain overall optimal health.

"Try adding some more chicory root, leeks, cabbage, chickpeas, lentils and beans to your diet because they are super high-fiber foods that also serve as prebiotics, which promote good bacteria in your gut," says Jenny Champion, RD, CPT.

3. Up Fermented Foods and Probiotics

Fermented foods are quite buzzy lately, and for good reason. These foods help strengthen your gut microbiome, according to Harvard Health Publishing. Using a tried-and-true method, fermented foods are preserved not only for a longer shelf life, but to boost nutritional value, too probiotics included.

Probiotics are specific strains of bacteria that add to the population of beneficial microbes in the gut, per the Mayo Clinic. If you see the words "naturally fermented" on food labels, you've found another gut-friendly food.

4. Dont Forget About Prebiotics

Many vegetables, whole grains and legumes contain prebiotics, which help the probiotics (aka good bacteria) flourish.

Image Credit: Sam Barnes/Moment/GettyImages

Another way to maintain a healthy balance of gut bacteria is by helping the beneficial microbes that are already in your microbiome to grow.

Enter prebiotics, plant fibers that act like fertilizers to stimulate growth, according to the International Food Council Foundation. You can find prebiotics in high-fiber fruits, veggies, whole grains and legumes, i.e. whole foods containing complex carbs. Since your body can't fully digest those carbs, they become food for your gut bacteria.

5. Avoid Sugar Substitutes

Sure, artificial sweeteners can be an easy way to save some calories when battling the scale, but your gut can take a beating if you have too much. Not only do they cause gas and diarrhea, but sugar substitutes can increase blood sugar and weaken insulin response by changing the composition of gut microbiota, according to a January 2019 article in Advances in Nutrition.

"If you're trying to kick that artificial sweetener habit, snack on more fresh fruit," Champion says. "It's always a safe bet when you need a sweet treat that's also good for you."

6. Have All the Polyphenols

Dietary polyphenols are substances found in plants that help feed those beneficial gut microbes.

Coffee, tea, red wine, chocolate, fruits and vegetables are great ways to give your gut nice doses of polyphenols, per a February 2019 article in Food and Function.

"Most polyphenols are not absorbed in the small intestine or upper GI tract, and go down to the large intestine where they are broken down by bacteria," gastroenterologist Jacqueline Wolf, MD, tells LIVESTRONG.com.

The products created as bacteria break down polyphenols may potentially have an effect on depression and other health conditions, she says. "There are studies showing that polyphenols can protect against chronic diseases such as cancers and cardiovascular diseases and have an impact on obesity."

7. Practice Good Oral Hygiene

The bacteria living in your mouth can migrate to your gut, altering your microbiome.

Image Credit: nortonrsx/iStock/GettyImages

Just like your gut, there are tons of bacteria living in your mouth. Oral bacteria involved in chronic gum infections can move down to the gut and alter the microbiota there, where they may play a role in certain metabolic disorders as well as some cancers, according to a March 2019 article in the Journal of Microbiology.

So, brush your teeth twice a day, floss, visit your dentist for cleanings and voice any concerns about your oral health: You'll be keeping more than your mouth healthy by doing so.

Getting more sleep is a on a lot of people's to-do lists, and for good reason. Yes, you're more alert and perform better with an adequate night's rest. But health problems can arise when you're not getting enough and can even possibly affect your gut, according to the Gastrointestinal Society.

"There's evidence from studies in irritable bowel syndrome that poor sleep is associated with increased abdominal pain the next day. This is supported by research in chronic pain, which suggests that sleep deprivation increases sensitivity to painful stimuli," says GI health psychologist Sarah Ballou, PhD.

"The activity of the digestive system depends on circadian cues so that, in general, the digestive system is less active at night," Ballou says. That means that when your circadian rhythm gets out of whack, it could lead to increased GI symptoms, she adds.

It's a well-known fact that exercise does wonders for you mentally and physically. And recent studies show its effects can even reach the tiny bacteria in your gut.

Working out can boost your amount of beneficial gut bacteria species, enrich your microbiota diversity and help in the development of new bacteria, according to a March 2017 article in Oxidative Medicine and Cellular Longevity. Exercising seems to be particularly beneficial for bacteria that can contribute to reducing weight and easing some GI and metabolic disorders.

Aim for 150 minutes of moderate activity each week, per the Mayo Clinic.

10. Go Easy on the Drinks

Too much alcohol could cause an imbalance of bacteria within your gut, which can lead to unpleasant GI symptoms.

Image Credit: Alexey Dulin / EyeEm/EyeEm/GettyImages

Having a drink here and there is perfectly OK, but when "here and there" turns into "one too many" pretty often, you can cause chaos in your gut.

Alcohol promotes dysbiosis (when environmental factors disrupts bacterial imbalance) and bacterial overgrowth, which can lead to inflammation, per a 2017 article in Alcohol Research Current Reviews. Cancers, liver disease and neurological pathologies may also be aggravated.

"Alcohol (particularly red wine) in moderation can actually be good for gut health, but of course too much of a good thing isn't necessarily better," Champion says. "Excessive booze-drinking can cause gut inflammation, reduce healthy bacteria while increasing harmful bacteria and cause chronic bloating and constipation."

11. Avoid Unnecessary Antibiotics

Sometimes prescription antibiotics are warranted in order to kill a bacterial infection, but they can cause gut disturbances. That's because antibiotics also kill "good" gut bacteria along with the "bad" bugs making you sick, creating dysbiosis, according to a May 2019 article in the Chinese Medical Journal. Different antibiotics or their combinations will result in different changes to the microbiome.

"With a change in the gut flora, diarrhea can occur due to the imbalance of the bacteria," Dr. Wolf says. "Some antibiotics are more likely to result in the overgrowth of Clostridia difficile that can cause severe diarrhea and colitis. Clindamycin and ciprofloxacin are two antibiotics with a higher risk for C. difficile. These two antibiotics cause a marked loss of mucosal barrier and immune function in the gut."

If you're currently on antibiotics, it's generally a good idea to eat plenty of probiotic-rich foods to help restore good-for-you gut bacteria.

OK, easier said than done. But life stressors can significantly change your microbiome. Microbes can respond to hormones and neurotransmitters that are involved in your stress response, according to February 2017 article in Hormones and Behavior. This can change the composition of your gut bacteria but more research is required to fully understand how this actually occurs and the effects.

Nonetheless, cramps, constipation, diarrhea and changes in appetite can all occur due to stress-related changes in gut bacteria, according to the Anxiety and Depression Association of America. And once you start dealing with one of these conditions, the condition itself can be a source of stress and anxiety, in turn worsening gut symptoms.

Breathing techniques, meditation, regular exercise and seeking out a mental health professional can all be helpful to try to lift some weight off your shoulders.

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Global Testosterone Replacement Therapy Market(Size) 2020- Research Report Presents a Overall Market and Growth Trends Analysis and Forecast 2023 -…

Global Testosterone Replacement Therapy Market Region-Wise and Country-Wise Market size(in terms of Value and Volume) Analysis and Forecast Report till 2023

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The plus point of this research study is that it includes the impact ofCOVID-19to the Testosterone Replacement Therapy market. The data summarized within this research study includes forecast from 2018 to 2023. COVID-19 has significantly impacted each and every market on the global platform. If you have any specific requirement then Please get in touch with us. Our Expert team will provide as per report customized to your requirement.

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Chapter 4. Testosterone Replacement Therapy Market Breakdown Data by Type and Application

Chapter 5. Testosterone Replacement Therapy Market by End Users/Application

Chapter 6. COVID-19 Outbreak: Testosterone Replacement Therapy Industry Impact

Chapter 7. Opportunity Analysis in Covid-19 Crisis

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Explained: How corona of the virus changes into a hairpin shape and why – The Indian Express

Written by Kabir Firaque | New Delhi | Updated: July 24, 2020 10:45:13 am Structure of SARS-CoV-2, including the spike protein. (Source: Wikipedia)

The spike protein of SARS-CoV-2 the corona in the coronavirus that causes Covid-19 disease has just revealed new secrets. Researchers have found that the spike protein changes its form after it attaches itself to a human cell, folding in on itself and assuming a rigid hairpin shape. The researchers have published their findings in the journal Science, and believe the knowledge can help in vaccine development.

It is a protein that protrudes from the surface of a coronavirus, like the spikes of a crown or corona hence the name coronavirus. In the SARS-CoV-2 coronavirus, it is the spike protein that initiates the process of infection in a human cell. It attaches itself to a human enzyme, called the ACE2 receptor, before going on to enter the cell and make multiple copies of itself.

Using the technique of cryogenic electron microscopy (cryo-EM), Dr Bing Chen and colleagues at Boston Childrens Hospital have freeze-framed the spike protein in both its shapes before and after fusion with the cell.

The images show a dramatic change to the hairpin shape after the spike protein binds with the ACE2 receptor. In fact, the researchers found that the after shape can also show itself before fusion without the virus binding to a cell at all. The spike can go into its alternative form prematurely.

Dr Chen suggests that assuming the alternative shape may help keep SARS-CoV-2 from breaking down. Studies have shown that the virus remains viable on various surfaces for various periods of time. Chen suggests that the rigid shape may explain this.

More significantly, the researchers speculate that the postfusion form may also protect SARS-CoV-2 from our immune system.

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The postfusion shape could induce antibodies that do not neutralise the virus. In effect, the spikes in this form may act as decoys that distract the immune system.

Antibodies specifically targeting the postfusion state would not be able to block membrane fusion (viral entry) since it would be too late in the process. This is well established in the field of other viruses, such as HIV, Chen told The Indian Express, by email.

In principle, if both conformations shared neutralising epitopes (the part of the virus targeted by antibodies), then the postfusion form too could induce neutralising antibodies, Chen said. But because the two structures are often very different, in particular, in case of SARS-CoV-2 and HIV, I think it is not very likely that the postfusion form would be useful as an immunogen, he explained.

Yes, both the before and after forms have sugar molecules, called glycans, at evenly spaced locations on their surface. Glycans are another feature that helps the virus avoid immune detection.

The researchers believe the findings have implications for vaccine development. Many vaccines that are currently in development use the spike protein to stimulate the immune system. But these may have varying mixes of the prefusion and postfusion forms, Chen said. And that may limit their protective efficacy.

Chen stressed the need for stabilising the spike protein in its prefusion structure in order to block the conformational changes that lead to the postfusion state. If the protein is not stable, antibodies may be induced but they will be less effective in terms of blocking the virus, he said.

Using our prefusion structure as a guide, we should be able to do better (introducing stabilizing mutations) to mimic the prefusion state, which could be more effective in eliciting neutralizing antibody responses, Chen told The Indian Express. We are in the process of doing this in case the first round of vaccines are not as effective as we all hope.

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The Ultimate Guide to Nutritionists and Dietitians in Boston – Boston magazine

Nutrition

These 14 experts can help you maintain a healthy relationship with food and your body.

Photo via Getty Images

Wading through diet culture these days can be tricky. On one hand, our culture has been conditioned to believe (incorrectly so) that to be skinnier is to always be healthierand to believe that self-restriction is always attainable and sustainable. On the other hand, America does have one of the highest rates of obesity in the world. Heres the thing: No matter where you fall on the scale, there are professionals here to help you navigate not only the grocery aisles, but your own internal narrative around food. This is, by no means, a comprehensive list of nutritionists and dietitians in Boston, but its a good start.

Before we dive in, though, its important to keep in mind the difference between nutritionists and dietitians. (No, theyre not the same thing!) Dietitians can be nutritionists, but not all nutritionists are dietitians. Dietitians must earn multiple degrees, pass multiple exams, and go through many hours of intensive supervised practice; they have far more experience, education, and expertise in giving medical nutrition advice. Meanwhile, since the term is not as highly regulated, anyone can self-identify as a nutritionist. (Read more here, to get a better understanding of the differentiation between the two.) While both can be helpful, weve focused on dietitians for the list below.

Karuna is a sanskrit word for self compassion, and this wellness studio makes compassion for your bodyand your choicescentral to its offerings. With two offices in Norwood and Franklin, Karuna has five dietitian nutritionists on staff offering nutrition counseling, cooking classes, and fitness classes. All offerings intertwine principals of Intuitive Eating (an approach that builds eating habits around internal body cues, rather than external cues) and the Health at Every Size ethos.

Matt Priven, owner and founder of Oceanside Nutrition, offers an array of focus areas for individual nutrition counseling, including Intuitive Eating, general nutrition, digestive health, and more. Oceanside has two offices in Boston and Newburyport, and is currently offering telehealth appointments.

Whether you feel out of control with food, miss out on life because of the way you feel about your body, or just feel really confused about what to eat, Alexis Penney, owner of Shanti Nutrition, can help. Her mission is to help women find more peace with food, health, and their bodies to live their best lives and feel empowered.

Kara Lydon is another anti-diet dietitian, here to help all people overcome their fixation on rigidity. Besides offering a wide array of nutrition counseling (on subjects like Intuitive Eating, eating disorders, and digestive orders) she also has a huge database of delicious and nutritious recipes on her blog. In addition, she has an ebook and offers yoga instruction.

Jillian Greaves is the dietitian mastermind behind Prevention Pantry Nutrition. She combines her passion for creating simple yet flavorful recipes with professional expertise in the nutrition sciencesall to help her clients increase energy, balance their hormones, and improve digestion. She offers in-person, one-on-one nutrition counseling at Back Bay Health and via telehealth appointments.

Celebrating the role food that plays in our cultures and traditions, Sally Cohen helps clients accomplish their goals with food and exercise through a non-diet approach. Shes also a running coach, so she marries the intricacies of sport performance with nutrition to help runners of all ability levels improve their training and overall healthy lifestyle.

Sydney Gatward, the registered dietitian behind Liberated Nutrition, uses Intuitive Eating principles and the Health at Every Size approach to help her clients break free from diet culture. She also specializes in hormonal imbalances, prenatal nutrition, and management of digestive complaints.

If youre having IBS issuesor any other type of digestive complaint, like bloatingLauren Adler Dear is your girl. Her business, Dear Nutrition, specializes in utilizing the Low FODMAP Diet, which limits foods with sugars that are hard for the human body to normally digest. She is also an Intuitive Eating and Health at Every Size dietitian, and built a passion for food from growing up cooking, gardening, and working on many organic farms after school.

Not only is Ryan Maciel a registered dietitian, but he is also a Certified Strength and Conditioning Specialist working at Catalyst Fitness in Cambridge to help people of all backgrounds build a sustainable and healthy nutrition and fitness practice.

With a functional medicine background and extensive knowledge on gut health, Bridgitte Carroll works with clients to get to the root of their health problems. She helps people build a sustainable nutrition, lifestyle, and supplement routine to help them start feeling better quicker. She also has a 12-week group coaching experience for those wanting to dive a little deeper into their gut health.

If you want to learn to love the skin youre in, build lifelong healthy habits that instill a better relationship with food, movement, and your body through Jessi Haggertys size-inclusive, anti-diet approach to health behavior change. Jessi is a registered dietitian offering medical nutrition therapy, Intuitive Eating counseling, and body image coaching.

Kathleen Johnson is the dietitian behind Halve Your Cake. She specializes in gut health, autoimmune disease, womens health, and general wellness.

Bringing more than 15 years of experience to his practice, George Mandler helps clients through both nutrition and acupuncture. He is a board certified registered dietitian and a licensed acupuncturist working out of an office in both Stow and Cambridge to help clients with pain, fertility challenges, digestive issues, and more.

At Riverside Nutrition, founder and registered dietitian Chloe Schweinshaut believes in a whole body, whole food approach. She offers nutrition counseling on weight issues, nutrition for first responders, allergies, and more plus corporate wellness programs.

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The Ultimate Guide to Nutritionists and Dietitians in Boston - Boston magazine