‘They’re really good men’: Victoria Beckham is proud of her sons – Martinsville Bulletin

Victoria Beckham feels "really proud" of her sons.

The 46-year-old designer has Brooklyn, 21, Romeo, 17, and Cruz, 15, with her husband David Beckham - with whom she also has nine-year-old daughter Harper - and has said she couldn't be happier with the way her sons are growing up, as they're "turning out to be really good men".

She said: "I feel really proud of our boys because they are turning out to be really good men. They work hard and they're kind, and being kind is key now. I think everybody should be kind - there are so many horrible things going on in the world. With regards to the boys they always have to have respect for themselves, for others, for girls. Our boys have always had the utmost respect for everyone. They have always been like that."

And for the former Spice Girls star, motherhood is her greatest achievement.

She added during an interview with photographer Alexi Lubimorski for his YouTube series: "Being a mum is the most important job in the world. I love what I do professionally and I take it very seriously but there is nothing more serious than having children. It's your responsibility to bring up really good, good people so I take that responsibility seriously. I try to be the best mum, I try to be the best wife, and I try and be the best professional."

Victoria has been staying at home with her family amid the coronavirus pandemic, and recently said her time in lockdown has been "precious".

She explained: "While working from home, we've been on walks every day as a family. How often would we all go on a walk together normally? Usually there's a conference call or a work meeting or someone is travelling abroad. These times are precious.

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'They're really good men': Victoria Beckham is proud of her sons - Martinsville Bulletin

The Arsenal of old: Twitter reacts to Mikel Arteta and Cos stunning FA Cup win over Manchester City – Scroll.in

Pierre-Emerick Aubameyang was the star of the show as Arsenal produced a fine performance to beat Manchester City and reach the FA Cup final on Saturday.

Gunners boss Arteta outwitted City manager Pep Guardiola with an astute counter-attacking scheme and Aubameyang struck in each half as Arsenal executed their plans to perfection. Arsenal will face Chelsea or Manchester United, who meet in the other semi-final on Sunday, in the final at Wembley on August 1.

Arteta captained Arsenal to FA Cup triumph six years ago and, in his first season in charge of the north London club, the Spaniard has led them back to the final of a competition they last won in 2017.

Just days after beating Premier League champions Liverpool, Arsenal offered further evidence that Arteta could be the man to restore them to the glory days of the Arsene Wenger era. Arsenal had lost their previous seven meetings with City, including a 3-0 drubbing in their first game after the coronavirus hiatus.

But, thanks to Artetas masterstroke, Arsenal handed Guardiolas side a first Wembley defeat in their last 10 visits.

Heres how Twitter reacted to the result:

(With inputs from AFP)

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The Arsenal of old: Twitter reacts to Mikel Arteta and Cos stunning FA Cup win over Manchester City - Scroll.in

Lawrence Livermore National Laboratory and Tyvak Nano-Satellite Systems Announce Agreement to Develop Innovative Telescopes for Nanosatellites -…

IRVINE, Calif., July 16, 2020 /PRNewswire/ --Lawrence Livermore National Laboratory (LLNL) and Tyvak Nano-Satellite Systems, Inc. have reached a cooperative research and development agreement (CRADA) to develop innovative compact and robust telescopes for nanosatellites.

The four-year, $2 million CRADA will combine LLNL's Monolithic Telescope (MonoTele) technology with Tyvak's expertise producing high-reliability spacecraft. In the future, the advanced optical imaging payloads may be employed to collect information for remote sensing data users.

The MonoTele consists of a space telescope fabricated from a single, monolithic fused silica slab, allowing the optic lens to operate within tight tolerances. This approach does not require on-orbit alignment, greatly simplifying spacecraft design and favorably affecting spacecraft size, weight and power needs.

"I'm excited about this technology transitioning from LLNL to space demonstration and eventual commercial use," said Alex Pertica, the deputy program leader for LLNL's Space Science and Security Program (SSSP).

Tyvak will provide the spacecraft and payload, consisting of the MonoTele, sensor, and electronics, ensuring survivability in a demanding vibration environment during launch and wide-ranging temperatures on-orbit.

LLNL will then apply its knowledge of novel optical payloads to develop, test, and process data gathered from the sensors.

"We are delighted to have formalized this collaborative effort with LLNL to demonstrate and commercialize advanced optical imaging technology," said Anthony Previte, Tyvak's CEO. "Together we will enable end users to achieve their mission goals in many space-based markets."

Developed by LLNL over the past eight years, the MonoTele space telescopes range in size from one inch (called the mini-monolith) to 14 inches.

The MonoTele technology provides imaging for nanosatellites, about the size of a large shoebox and weighing less than 22 pounds, and microsatellites, about the size of a dorm refrigerator and weighing up to several hundred pounds.

LLNL researchers undertook the development of the tiny one-inch, mini-monolith for use in star trackers, a component that every satellite has one or more of, and is used to find the satellite's "attitude" or orientation. Attached to the satellite's body, the star trackers compare the satellite's position relative to the position of the stars to determine their orientation.

"Several telescopes with the MonoTele technology have flown in space. They've performed very well," Pertica said, adding that the one-inch, mini-monolith version is now flying aboard Tyvak-0129. The technology's first space mission was the GEOstare satellite, which launched in January 2018.

Typically, space telescopes have two optical mirrors a larger primary mirror and a smaller secondary mirror that face each other. If the mirrors go out of alignment, the image becomes fuzzy.

To keep the mirrors in alignment, a metering structure is typically employed to maintain the mirrors in place. But metering structures can be expensive and can go out of alignment.

To solve this problem, LLNL optical scientist Brian Bauman came up with the idea of the MonoTele replacing the two mirrors and metering structure with one solid piece of glass, with optical shapes and reflective coatings at both ends of the glass.

The MonoTele concept was inspired by the design of the mirrors used for the Large Synoptic Survey Telescope that is under construction in Chile, due to come online in 2023 and expected to image some 20 billion galaxies.

Under this CRADA, LLNL and Tyvak expect to develop additional MonoTele-type telescopes capable of operating in other wavelength bands, such as ultraviolet and short-wave infrared, and as a spectrometer instrument.

The telescopes, which would be demonstrated in space, also would feature compact and low-power focus mechanisms for missions requiring agile optics technology.

The MonoTele nanosatellite imaging payloads can be used across multiple applications and will serve Earth observation, space situational awareness, and satellite navigation initiatives.

"Partnering under a CRADA with outside industry was the natural next step for commercializing the technology," said David Dawes. "We look forward to working with Tyvak."

"The CRADA gives Tyvak the option to license LLNL intellectual property (IP) or joint IP developed under this collaboration, in addition to any of the Lab's existing background IP required to practice the subject inventions," Dawes added.

About Lawrence Livermore National Laboratory (LLNL)

Founded in 1952, Lawrence Livermore National Laboratory (www.llnl.gov) provides solutions to our nation's most important national security challenges through innovative science, engineering and technology. Lawrence Livermore National Laboratory is managed by Lawrence Livermore National Security, LLC for the U.S. Department of Energy's National Nuclear Security Administration.

About Tyvak Nano-Satellite Systems, Inc.

Founded in 2013 and headquartered in Irvine, California, Tyvak Nano-Satellite Systems, Inc. is an industry leader, delivering optimized, end-to-end satellite solutions. For more information, please visit http://www.Tyvak.com or follow the Company @TyvakNanoSat

Media Contacts:

LLNL

Stephen Wampler[emailprotected] +1 (925) 423-3107

Tyvak

Taylor Cantwell[emailprotected] +1 (949) 439-6153

SOURCE Tyvak Nano-Satellite Systems, Inc., a Terran Orbital Corporation

http://www.tyvak.com

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Viewed through revamped slide, cancer cells show their hidden side : The Asahi Shimbun – Asahi Shimbun

SAPPORO--Cancer cells play dead to dodge attacks by immune cells, a scientist here discovered, and tumor tissue moves like a slug to fuse with other tumors, revelations that could trigger a breakthrough in the development of carcinoma treatment.

The phenomena were uncovered using a special glass slide that promotes the growth of cancer cells for in-depth observation developed by Yukiko Miyatake, 47, an assistant professor of experimental pathology at the Faculty of Medicine of Hokkaido University.

Miyatake designed the slide with tiny bumps on its surface in order to stimulate cells so they turn into tumor tissue.

To closely observe cancerous cells, Miyatake utilized a technique developed by Kaori Shigetomi, a specially appointed associate professor of micro- and nano-engineering at the universitys Institute for the Advancement of Higher Education.

The method created by Shigetomi, 45, allows one to two cells to be cultured on the slide, by taking advantage of semiconductor substrate development technology.

Miyatake said she expects the technique to become commercially available within a year.

In 2018, Miyatake succeeded in imaging through a microscope how cells gather, grow and convert into cancer tissue on a rough-surfaced glass slide measuring 2 centimeters by 2 cm and repeated the experiment to confirm her results.

Initially, she couldnt figure out why cells grew so smoothly on the special material. A one-year analysis revealed that the bumps on the surface offer the foundation for cells to develop into cancer tissue.

During a more detailed examination, Miyatake found a mature tumor merged with another to grow even bigger, moving around like a slug. She said she was surprised that the minor difference on the glass surface could physically stimulate cells into forming tissue.

ZOMBIE TISSUE

When carcinoma cells killed by exposure to strong ultraviolet rays were put on the slide, tumors took in deceased cells around them, to in effect play dead, rendering it impossible for immune cells that attack cancer cells to target them.

By donning the veil of dead cells like a zombie, tumors may be trying to evade being attacked by immune cells, Miyatake said.

Working with a major manufacturer, Miyatake is now creating a prototype for mass production. If the cell growth observation technology is commercialized, a new anti-cancer agent might be developed, she said.

Miyatake, who majored in virus research in university, said she is inspired to work harder by longtime friends and scientists she first met then who are now devoting themselves to research related to the novel coronavirus.

As someone involved in academic research, my goal is to save the lives of patients and contribute to society, Miyatake said.

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Viewed through revamped slide, cancer cells show their hidden side : The Asahi Shimbun - Asahi Shimbun

With Fedora 33, Nano Will Be The Default Terminal Text Editor – Fossbytes

Which is your favorite Linux terminal text editor? I guess it must be one from the never-ending list of candidates, including Vim and Nano. Even if youre free to install and use any editor, sometimes you chose the one installed by default. Thats why the default text editor matters.

Speaking of the Fedora system, Vi is the current default terminal text editor in most cases, such as git commit and command-line text editing. Now if you want Nano in Fedora, you have to run a single command dnf install nano. But with the upcoming Fedora 33, you no longer need to run any command to get Nano.

Yes, this is because the Fedora developer team has decided to ship the terminal text editor, GNU Nano, by default. This means Nano will replace Vi as the default editor in Fedora 33 Linux distribution.

If youre confused between Vi and Vim, let me tell you that Vim is an improved version of Vi with additional features.

The change comes amid the ongoing development for the upcoming Fedora 33. Along with othersystem-wide changes, a proposal was sent to make Nano the default text editor.

Later, during the Fedora Engineering and Steering Committee (FESCo) meeting last week, several features for Fedora 33 were approved, including Nano text editor by default in the Fedora system.

As the proposal cites, users need to learn the mode concept of Vi even for basic editing tasks. It makes it hard for new users to understand and use Vi.

Unlike Vi, Nano doesnt have any modes, which gives the user a shallow learning curve and lets them interact directly with text using user-friendly graphical text editing.

Hence, this proposal will make Nano the default editor across all of Fedoras editions. However, you still have vi pre-installed owing to the vim-minimal package.

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With Fedora 33, Nano Will Be The Default Terminal Text Editor - Fossbytes

Clean Seed to deploy their patented SMART technologies to modernize the agricultural sector – Proactive Investors USA & Canada

Clean Seed Capital (CVE: CSX- OTC: CLGPF) Chief Operating Officer Colin Rush joined Steve Darling from Proactive Vancouver to discuss the company that is continuing to pioneer the modernization of the crop/food production industry with cutting edge SMART technologies that include their upcoming SMART Seeder MAX and MAX-S seeding and planting systems.

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Clean Seed to deploy their patented SMART technologies to modernize the agricultural sector - Proactive Investors USA & Canada

Five Indian Americans Receive US DoE Early Career Award – The Indian Panorama

BOSTON (TIP): The U.S. Department of Energy (DoE) recently announced the names of 76 scientists who have been selected for their2020 Early Career Research Program. The list includes five Indian Americans.

They are: Arun Devaraj, Pacific Northwest National Laboratory (WA), Ranganathan Gopalakrishnan, University of Memphis, Siddharth Karkare, Arizona Board of Regents for Arizona State University, Vedika Khemani, Stanford Junior University, and Karthish Manthiram, MIT.

Under the program, university-based researchers will receive grants for at least $150,000 per year and researchers based at DOE national laboratories will receive grants for at least $500,000 per year. The research grants are planned for five years and will cover salary and research expenses.

Arun Devaraj, Pacific Northwest National Laboratory (WA)

Dr. Arun Devaraj is a Material scientist in the Physical and Computational Sciences Directorate. His research focus is in microstructure-property relationship of metallic alloys, oxides and composite materials. Dr. Devaraj has extensive experience specifically in applying atom probe tomography (APT) for material characterization, in addition to scanning electron microscopy (SEM), energy dispersive x-ray spectroscopy (EDS), focused ion beam (FIB), transmission electron microscopy (TEM), x-ray absorption near edge spectroscopy (XANES), scanning transmission x-ray microscopy (STXM) and in-situ high energy x-ray diffraction (HEXRD) at beamlines of various DOE synchrotron facilities.

Ranganathan Gopalakrishnan is an Assistant Professor in the Department of Mechanical Engineering at the University of Memphis. His research focuses on applying aerosol science and technology to Additive Manufacturing (AM) processes as well as fundamental aspects of aerosol science.

Siddharth Karkare is an assistant professor in the Department of Physics at Arizona State University. He comes to ASU following a 3-year post-doctoral research position at the Lawrence Berkeley Lab. His research is at the interface of accelerator physics and nano-science and focuses on the generation and manipulation of bright electron beams for various applications ranging from meter-scale electron microscopes to large km-scale particle colliders and free-electron lasers.

Vedika Khemani Assistant Professor of Physics at Stanford completed her undergraduate studies at Harvey Mudd College, and her PhD at Princeton University. She was a Junior Fellow at Harvard University before starting as assistant professor at Stanford University. She works on theoretical investigations of quantum many-body systems and how they evolve dynamically.

Karthish Manthiram, the Theodore T. Miller Career Development Chair and Assistant Professor in Chemical Engineering in MIT, is working to synthesize chemicals and materials that we encounter every day in a sustainable manner that eliminates the carbon footprint. With the support of the DoE Early Career Award, the Manthiram lab is specifically looking at how water can be used as a source of oxygen atoms to convert alkenes, which are two carbon atoms attached by a double bond, into an epoxide, a triangular configuration of two carbon atoms and an oxygen atom.

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Five Indian Americans Receive US DoE Early Career Award - The Indian Panorama

Global report: WHO reports record daily increase of coronavirus cases – The Guardian

Irans president says an estimated 25 million people in the country could be infected with the coronavirus, way above the countrys official rate, as the World Health Organization reported a record daily increase of new cases of more 270,000.

Hassan Rouhani told a summit of the countrys coronavirus taskforce on Saturday that the health ministry estimated about 25 million Iranians might have contracted the virus and warned up to 35 million more might become infected in the months ahead.

The method by which the figure was derived was not disclosed, but the estimate gave an insight into the scale of the outbreak in the worst-hit country in the Middle East, with 270,000 confirmed cases and at least 13,979 deaths.

Rouhanis deputy head of communications, Alireza Moezi, added on Twitter that the 25-million estimate referred to those who have encountered the virus and achieved complete immunity.

We have to consider the possibility that 30 to 35 million more may face infection, Rouhani told a televised meeting of the task-force. We have not yet achieved herd immunity and we have no choice but to be united and break the chain of transmission of the coronavirus.

Iran refrained from fully locking down its population of 81 million but closed schools, cancelled public gatherings and banned movement between provinces in March. It lifted most of the restrictions a month later to relieve the impact of the closures on its ailing economy.

Australia postponed the next sitting of its national parliament as cases continued to surge in and around its second-largest city, Melbourne. A second lockdown has been imposed on the southern state of Victoria, weeks after the initial wave of restrictions was lifted and community transmission briefly appeared to have been eradicated.

The national body will be suspended for two weeks to account for the risk of politicians in Victoria spreading the virus to the capital, Canberra, and the surrounding state of New South Wales, the Australian prime minister, Scott Morrison, said on Saturday.

The risks posed by a parliamentary sitting are significantly higher and unlikely to be resolved in the next month, he said.

As the global count of cases being tracked by Johns Hopkins University crossed 14m, with nearly 600,000 deaths, France announced that masks would be made mandatory in enclosed public spaces including banks, shops and indoor markets starting on Monday.

The reproduction rate of the virus in the Brittany region has risen sharply in the past weeks, raising fears the virus may be regaining momentum in the country.

The WHO reported the greatest daily increase in global cases, with the total rising by 237,743 in the 24 hours to Saturday. The biggest increases were reported in the US, Brazil, India and South Africa.

Cases in the US grew by more than 76,000, a record for the worlds worst-hit country.

In a lecture for the Nelson Mandela Foundation, delivered online, the UN secretary-general Antnio Guterres said the pandemic had revealed, like an x-ray, fractures in the fragile skeleton of the societies we have built.

It is exposing fallacies and falsehoods everywhere: the lie that free markets can deliver healthcare for all; the fiction that unpaid care work is not work; the delusion that we live in a post-racist world; the myth that we are all in the same boat, said Guterres, a former Socialist prime minister of Portugal.

He added that the coronavirus outbreak had created a generational opportunity to build a more equal, sustainable world. Because while we are all floating on the same sea, its clear that some are in superyachts while others are clinging to the floating debris, Guterres said.

The UN has appealed for $10.3bn (8.2bn) to help poor states, but has received only $1.7bn.

China launched mass health screenings in the western Xinjiang province after a spike in cases raised fears of a fresh outbreak. Flights into the regional capital rmqi were suspended along with the citys subway services after 17 cases were found on Saturday.

The whole city has entered a wartime state, and will suspend all kinds of group activities, state media quoted an official giving a briefing.

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Global report: WHO reports record daily increase of coronavirus cases - The Guardian

After the Recent Surge in Coronavirus Cases, Deaths Are Now Rising Too – The New York Times

The reopening and relaxing of social distancing restrictions in some states may be contributing to the first noticeable nationwide increase in coronavirus fatalities since April, when the pandemic initially peaked.

The number of cases in late June surged higher than during the outbreaks first peak. At this same time, daily Covid-19 fatalities decreased slightly, leading President Trump to proclaim that deaths were way down. But that divergence may have come to an end last week, when the average number of new deaths per day began steadily rising again.

Where deaths have increased since June 1

Daily new deaths since June 1

States where deaths have increased since June 1

Daily new deaths since June 1, seven-day average

Note: Data as of July 15.

Public health experts have pointed to a few factors that help explain why the death count was initially flat. Treatment has improved and young people, who are less likely to die from Covid-19, make up a larger share of new cases.

Additionally, more widespread testing means cases are caught sooner, on average. That means that the lag between diagnosis and death would be longer than in March, when tests were in critically short supply.

That lag may have come to an end last week, as the number of new deaths began to rise. Many of the states that reopened early are the ones seeing the biggest increases, while New York, the countrys hardest-hit city, has seen a 64 percent drop since June 1.

Deaths in New York, New Jersey and Connecticut

Deaths in rest of the United States

While the growth rate of new deaths has flattened slightly in the past few days, data suggest that the recent increase in deaths may continue. Most of the states seeing the sharpest increase in deaths also have some of the countrys highest positive test rates, as well as soaring hospitalization rates, an indicator that many more residents may be gravely ill.

In addition, a high share of positive tests most likely signals that there are a larger number of people whose infections are going undetected in a states official numbers.

Sources: New York Times database from state and local governments; the Covid-19 Tracking ProjectNote: Data is as of July 15, 2020. States listed above have a minimum of 100 cumulative deaths. Positive test rates are calculated using positive results from July 2 to July 15. Trend lines and new deaths per million show seven-day average data.

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After the Recent Surge in Coronavirus Cases, Deaths Are Now Rising Too - The New York Times

A Shutdown May Be Needed to Stop the Coronavirus – The New York Times

When you mix science and politics, you get politics. With the coronavirus, the United States has proved politics hasnt worked. If we are to fully reopen both the economy and schools safely which can be done we have to return to science.

To understand just how bad things are in the United States and, more important, what can be done about it requires comparison. At this writing, Italy, once the poster child of coronavirus devastation and with a population twice that of Texas, has recently averaged about 200 new cases a day when Texas has had over 9,000. Germany, with a population four times that of Florida, has had fewer than 400 new cases a day. On Sunday, Florida reported over 15,300, the highest single-day total of any state.

The White House says the country has to learn to live with the virus. Thats one thing if new cases occurred at the rates in Italy or Germany, not to mention South Korea or Australia or Vietnam (which so far has zero deaths). Its another thing when the United States has the highest growth rate of new cases in the world, ahead even of Brazil.

Italy, Germany and dozens of other countries have reopened almost entirely, and they had every reason to do so. They all took the virus seriously and acted decisively, and they continue to: Australia just issued fines totaling $18,000 because too many people attended a birthday party in someones home.

In the United States, public health experts were virtually unanimous that replicating European success required, first, maintaining the shutdown until we achieved a steep downward slope in cases; second, getting widespread compliance with public health advice; and third, creating a work force of at least 100,000 some experts felt 300,000 were needed to test, trace and isolate cases. Nationally we came nowhere near any of those goals, although some states did and are now reopening carefully and safely. Other states fell far short but reopened anyway. We now see the results.

While New York City just recorded its first day in months without a Covid-19 death, the pandemic is growing across 39 states. In Miami-Dade County in Florida, six hospitals have reached capacity. In Houston, where one of the countrys worst outbreaks rages, officials have called on the governor to issue a stay-at-home order.

As if explosive growth in too many states isnt bad enough, we are also suffering the same shortages that haunted hospitals in March and April. In New Orleans, testing supplies are so limited that one site started testing at 8 a.m. but had only enough to handle the people lined up by 7:33 a.m.

And testing by itself does little without an infrastructure to not only trace and contact potentially infected people but also manage and support those who test positive and are isolated along with those urged to quarantine. Too often this has not been done; in Miami, only 17 percent of those testing positive for the coronavirus had completed questionnaires to help with contact tracing, critical to slowing spread. Many states now have so many cases that contact tracing has become impossible anyway.

Whats the answer?

Social distancing, masks, hand washing and self-quarantine remain crucial. Too little emphasis has been placed on ventilation, which also matters. Ultraviolet lights can be installed in public areas. These things will reduce spread, and President Trump finally wore a mask publicly, which may somewhat depoliticize the issue. But at this point all these things together, even with widespread compliance, can only blunt dangerous trends where they are occurring. The virus is already too widely disseminated for these actions to quickly bend the curve downward.

To reopen schools in the safest way, which may be impossible in some instances, and to get the economy fully back on track, we must get the case counts down to manageable levels down to the levels of European countries. The Trump administrations threat to withhold federal funds from schools that dont reopen wont accomplish that goal. To do that, only decisive action will work in places experiencing explosive growth at the very least, limits even on private gatherings and selective shutdowns that must include not just such obvious places as bars but churches, also a well-documented source of large-scale spread.

Depending on local circumstances, that may prove insufficient; a comprehensive April-like shutdown may be required. This could be on a county-by-county basis, but half-measures will do little more than prevent hospitals from being overrun. Half-measures will leave transmission at a level vastly exceeding those of the many countries that have contained the virus. Half-measures will leave too many Americans not living with the virus but dying from it.

During the 1918 influenza pandemic, almost every city closed down much of its activity. Fear and caring for sick family members did the rest; absenteeism even in war industries exceeded 50 percent and eviscerated the economy. Many cities reopened too soon and had to close a second time sometimes a third time and faced intense resistance. But lives were saved.

Had we done it right the first time, wed be operating at near 100 percent now, schools would be preparing for a nearly normal school year, football teams would be preparing to practice and tens of thousands of Americans would not have died.

This is our second chance. We wont get a third. If we dont get the growth of this pandemic under control now, in a few months, when the weather turns cold and forces people to spend more time indoors, we could face a disaster that dwarfs the situation today.

John M. Barry is a professor at the Tulane University School of Public Health and Tropical Medicine and the author of The Great Influenza: The Story of the Deadliest Pandemic in History.

The Times is committed to publishing a diversity of letters to the editor. Wed like to hear what you think about this or any of our articles. Here are some tips. And heres our email: letters@nytimes.com.

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A Shutdown May Be Needed to Stop the Coronavirus - The New York Times

What the Coronavirus Brought Relationships: Clarity – The New York Times

I feel like the party line has always been that everybody should decide, not slide into cohabitation, said Alexandra Solomon, a clinical assistant professor of psychology at Northwestern University and the instructor of Northwesterns Marriage 101 course. What I have realized with the quarantine is what a privileged position that is. Its a privilege to make very mindful, thoughtful, intentional choices about when to move in together.

Of course, involuntary home confinement and financial strain against the backdrop of a global health crisis do not add up to domestic bliss for everyone. Joel Velez, 42, was quarantined in Florida with his wife of 18 years and their four children for about a month before he lost his job, for which he worked nights, in a layoff.

For the first time in years, Mr. Velez and his wife were on similar schedules, but their new abundance of time together confirmed something hed suspected for a while. We seem to have lost any kind of common ground besides, you know, where we live and our kids, he said. Last month, Mr. Velez suggested they see a counselor. According to Mr. Velez, his wife suggested they split up instead.

Mr. Velez wondered aloud whether, if the pandemic had never happened, his marriage might have limped along for another 15 years, neither party ever rising to the task of asking for a change.

This whole quarantine situation has forced us to face the problems that weve been experiencing, he said. To stop hiding from each other through work, or through our different schedules.

Robert Falconer, 29, and Julie Fisher, 28, live in Calgary, Alberta, and when their city began to shut down, they, too, had to immediately address a matter theyd been putting off: They had been talking about getting engaged, but there was always just a little too much going on in their lives.

In mid-March, Mr. Falconers parents, who were living in Asia, decided to come and live with him. Mr. Falconer and Ms. Fisher realized they would have to forgo seeing each other in person for a while to minimize exposure risks for their families. All at once, they had to choose: throw together a proposal straightaway, or wait until they could be together in person again, whenever that might be.

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What the Coronavirus Brought Relationships: Clarity - The New York Times

Global report: coronavirus infections in India pass 1m as outbreaks flare globally – The Guardian

India has become the third country to record more than 1m coronavirus infections, following the US and Brazil, as it reported 34,956 new cases in the past 24 hours, taking the national total to 1,003,832.

New peaks continue to appear around the world, including an alarming rise in the Brittany region of France.

Amid evidence that the disease was taking hold in poorer, rural areas of India with less effective public healthcare, the latest tally prompted renewed concerns about the countrys ability to cope with rising infections.

The figures have been released after a week in which authorities in India were forced to impose new lockdowns, including fresh restrictions on 128 million people in the state of Bihar, which came into force on Thursday.

The continuing and escalating outbreaks, on top of record cases in the United States which passed 75,000 daily cases in the last count have dampened hopes that the pandemic is anywhere close to being brought under control, even as researchers race to find a viable vaccine.

Three states in India Maharashtra, Delhi and Tamil Nadu account for more than half of the total cases in the country so far. Ashish Jha, the director of the Harvard Global Health Institute, warned that the majority of cases in the country were still being missed.

The continuing rise has forced authorities to reinstate lockdowns in some cities and states.

In Bangalore, the government ordered a week-long lockdown that began on Tuesday evening after a rapid rise in cases.

Dr Anant Bhan, a global health researcher, said India was likely to experience a series of peaks as the virus spread in rural areas. He said the capital, New Delhi, and the financial capital, Mumbai, had already recorded surges, while infections have now shifted to smaller cities.

Indias response to the virus was initially sluggish, but on 24 March the prime minister, Narendra Modi, imposed a three-week nationwide lockdown of its 1.3-billion population.

By Friday more than 13.8m infections had been confirmed worldwide and nearly 590,000 people had died, according to Johns Hopkins University, with Brazil recording more than 2m infections by the end of the week and the US more than 3m.

Countries around the world have moved quickly to reintroduce restrictions as outbreaks flare up again. Ada Colau, the mayor of Barcelona, Spains second largest city, announced a ban on gatherings of more than 10 people from Saturday as part of a package of measures to curb an increase in coronavirus cases in the Catalan capital.

We have to avoid gatherings of more than 10 people Only 10 people will be allowed in weddings and funerals from Saturday, Colau told a press conference. Residents were urged to shop online and cultural and sports events will also be limited.

In France, which had already announced plans to make mask wearing mandatory in enclosed public spaces, authorities reported a sharp rise in the infection rate in Brittany. According to data released on Friday, the diseases reproduction rate in Brittany had risen from 0.92 to 2.62 between 10-14 July.

Its a worrying number because it means the epidemic is taking off again, Eric Caumes, an infectious disease specialist at the Pitie-Salpetriere hospital in Paris, told BFM TV.

In China, flights into the city of rmqi in the far-western Xinjiang region were restricted on Friday, and underground and public bus services suspended, according to local social media.

The latest outbreak has underlined the continuing difficulty China faces in stamping out the virus even with its imposition of draconian measures which first emerged in the central Chinese city of Wuhan late last year.

Amid fears around the world over the ease in which new resurgences have escalated after countries relaxed restrictions, Hong Kong reported 50 new locally transmitted cases on Friday, stoking further concern about a third peak of infections in the global financial hub.

Tokyo hit a daily high of 293 infections as Japan tried to keep the worlds third-largest economy running while curbing infections, a precarious balancing act of opening restaurants and theatres with limited seating, and having store clerks work behind plastic shielding.

We have asked people and businesses to raise their alert levels, said Tokyos governor, Yuriko Koike. She said the recent higher numbers partly reflected more aggressive testing.

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Global report: coronavirus infections in India pass 1m as outbreaks flare globally - The Guardian

These self-cloning ticks could spread to Maine, experts say – WGME

{p}This undated photo provided by Rutgers University shows three Longhorned ticks: from left, a fully engorged female, a partial engorged female, and an engorged nymph. (Jim Occi | Rutgers University via AP){/p}

(BDN) -- Maine tick experts are keeping an eye out for the Asian longhorned tick, a foreign tick species that can reproduce without mating and has been documented as close as Connecticut.

Reported for the first time in the United States in 2017, this tick species has now established populations in at least 12 states, all of which are in the northeastern half of the country.

Its certainly something that is on every tick researchers radar here in the eastern United States, said Griffin Dill, who manages the Tick Lab, located in the new UMaine Cooperative Extension Diagnostic and Research Laboratory in Orono. This species seems to primarily reproduce through parthenogenesis, which makes its ability to increase its population size rapidly an important factor.

Parthenogensis is a form of asexual reproduction in which growth and development of embryos occur without fertilization by sperm. Female Asian longhorned ticks can lay eggs, which will develop and hatch on their own. Because of this, a single female tick can establish a fast-growing population.

The Asian longhorned tick is known to carry and transmit a variety of dangerous diseases in its home range in Asia, but those diseases have yet to be documented in the Asian longhorned tick populations found in the U.S. However, there is a concern that the species could pick up and transmit diseases that already occur in the U.S. in other tick species, such as anaplasmosis, babesiosis and Powassan virus.

There are a couple of pathogens in Asia that they are believed to transmit that are closely related to pathogens we have here, so its possible, said Dill. But from what weve seen so far in other states, [the ticks] risk to humans is thought to be relatively low at the moment. And we havent seen indication that its able to contribute to the transmission of Lyme disease.

In the U.S., East Asia and other areas where this tick has been found, such as New Zealand and Australia, it is considered to be a serious threat to livestock such as cattle and sheep. Major infestations can cause stress on an animal, reducing its growth and production. And in some cases, infestations can kill animals due to blood loss.

From limited studies that have been done on this species, they do seem to prefer feeding on animal hosts as opposed to humans, Dill said.

A new study in the journal Zoonoses and Public Health, published earlier this month, investigates the origin of this tick species and how they are spreading across the country.

Researchers gathered samples of Asian longhorned ticks across the U.S. and internationally, then used gene sequencing to compare various populations. The results indicate that at least three individual ticks from self-cloning populations were somehow transported to the U.S., and this explains why all adult Asian longhorned ticks found in the U.S. so far have been female. With Asian longhorned ticks that reproduce through parthenogenesis, male offspring are rare.

(In Asia, male Asian longhorned ticks do exist in some populations where they participate in reproduction.)

The study also found that these original ticks most likely came from East Asia.

While the first established Asian longhorned tick population in the U.S. was documented in New Jersey in 2017, researchers believe the species had been flying under the radar in the country for several years.

Theres a whole lot we dont know about it, said Chuck Lubelczyk, vector ecologist at Maine Medical Center Research Institute. Right now, the states where its occurring tend to be doing a lot more research on it [than other states], and I think a lot more research is going to be done on it as time goes by. Its a public health issue thats been introduced to the country and we werent really talking about it before it arrived here. We were kind of unprepared for it.

Its believed that the tick species can easily be spread by wildlife, as well as the transportation of livestock and domestic animals, such as dogs.

There are some pretty good regulations in place in terms of livestock transport, Lubelczyk said. But it certainly speaks to people needing to be vigilant about tick control medicines for their dogs and other domestic animals.

In the U.S., Asian longhorned ticks have been collected from deer, dogs, raccoons, cats, opossums and a number of other warm-blooded animals, as well as a variety of birds, according to data collected by the U.S. Department of Agriculture. Theyve also been found feeding on people.

Because of the wide geographical range that the species already inhabits, Lubelczyk believes it could survive Maines climate, even the states cold winters.

At least in southern Maine, I dont think itd have a problem, Lubelczyk said. How it would do up in northern Maine? I dont have a guess.

Moving forward, tick experts ask that Maine people be on the lookout for this invasive tick species; however, theyre difficult to identify. Adults are plain brown but can look similar to brown dog ticks and rabbit ticks, both of which live in Maine.

Researchers from the Maine Tick Lab and Maine Medical Center Research Institute are looking for Asian longhorned ticks, as well as the lone star tick (which has been found in Maine, but not yet in breeding populations), when conducting on-the-ground tick surveillance throughout the state.

In addition, they receive information about tick populations in Maine from the public sending tick samples to the Maine Tick Lab in Orono. The lab identifies these tick samples for free, and for an additional fee of $15 will test deer ticks for three common diseases they carry: Lyme disease, babesiosis and anaplasmosis. For more information, visit extension.umaine.edu/ticks.

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These self-cloning ticks could spread to Maine, experts say - WGME

How genetic studies will become the holy grail to find cancer biomarkers in future – Express Healthcare

Dr Villoo Morawala-Patell, Founder, Avesthagenand her team has been researching on genetic basis of disease risk associated with longevity and the endogamy prevalent within various communities. Theirpurpose is to deliver population-specific qualified biomarker targets to achieve the holy grail of genomics predictive, preventive, and personalised medicines. In an interview withRaelene Kambli, Dr Patell reveals more on their research and its application in the development and validation of cancer biomarker. She also delved into explaining theneed for a cross-disciplinary integration of scientific and clinical expertise for research especially in the field of cancer

What according to you is the most promising area of your current research?

The most promising area of our current work in terms of innovation is the significant and prolific outcomes from the Avestagenome Project for cancers, neurodegenerative conditions, and rare diseases. Our recent work on the genomics of the Zoroastrian-Parsis converges, ancient history, human migration, endogamous population genetics, social behaviour and customs that express in genetic signatures of wellness and health.

Specifically, we present a population genetics study wherein we assembled the first,de novoZoroastrian-Parsi Mitochondrial Reference Genome from one individual and the first Zoroastrian-Parsi Mitochondrial Consensus Genome derived from the assembly of 100 complete mitochondrial genomes of the dwindling, endogamous, non-smoking Zoroastrian-Parsi community of India. Phylogenetic analysis of the 100 Parsi mitochondrial genome sequences, showed a largely Persian origin for the Parsi community of India.Disease association mapping showed that the majority of the mitochondrial variants to be linked longevity and its associated conditions revealing the genetic basis for many of the heritable diseases in the community like cancer, neurodegenerative diseases like Parkinsons, Alzheimers and many rare genetic conditions.Our study is a first in tackling the genetic basis of disease risk associated with longevity and the endogamy prevalent within the community. The outcome of this study has an impact on all populations

So, your paper suggests that Zoroastrian-Parsi genes may help scientists characterise biomarkers predictive of diseases caused by tobacco use, such as lung, head and neck, and oesophagus cancers. Can you elaborate on the same?

We found 420 mitochondrial variants in our analysis of the 100 Zoroastrian-Parsi mitochondrial genomes. The detailed analysis brought to light the absence in the Zoroastrian-Parsi samples variants in mitochondrial genes like ND5, ND6 and tRNA that are shown to be associated with lung cancer and non-small cell lung cancer in other non-Parsi populations. Many of these reported genes have been associated with smoking-induced lung cancer and other smoking-induced cancers. Our study thus serves as a biological validation ofa well-known cultural phenomenon, reflecting the practice of abstinence from smoking in Zoroastrian-Parsis whose origins date back a millennium.

How helpful is this information for your research and what does it imply?

Our study is unique and provides a road map for understanding the genetic factors that underlie ageing and longevity associated diseases. A vast majority of the 420 mitochondrial variants are associated with longevity and conditions like Parkinsons disease, Alzheimers disease as well as breast, colon, prostate, ovarian cancer, infertility disorders like asthenozoospermia and rare neuronal diseases associated with mitochondrial dysfunction. Indeed, epidemiological studies of the community do show a preponderance of these diseases and a strong bias for the inheritance of these genetic disease variants owing to the practice of endogamy within the community. Our current study will complement our research goals as we accelerate our whole-genome analysis of the Parsi community to identify from the control population, alongside other comparative population subjects. The purpose is to deliver population-specific qualified biomarker targets to achieve the holy grail of genomics predictive, preventive, and personalised medicines.

What are the key findings of this study?

Our insights from the assembly of the archetypical Zoroastrian-Parsi mitochondrial genome extend from human migration to the genetic basis of disease prevalence. Our phylogenetic analysis showsalargely Persian origin for the Parsi community and revealed the presence of seven major haplogroups and 25 sub-haplogroups in our study group.We believethe strict endogamy practised by the Zoroastrian-Parsi community, has meant that their maternally inherited mitochondrial genome has remained largely unchanged from that of their ancestors in Old Persia. We also see the prevalence of genetic variants, specifically 217 unique variants linked to longevity and 41 longevity associated conditions like cancers, neurodegenerative disease, and rare diseases. We did not find any mitochondrial variants previously reported for lung cancer in our study and found an extremely low frequency of mutational signatures linked to tobacco carcinogens, reflective of the strong disapproval of smoking in the Zoroastrian religion. Another exciting outcome of our study is the discovery of 12 unique mitochondrial gene variants distributed across 27 subjects that have not been reported in public databases that index mitochondrial variants discovered thus far in other studies. We are currently in the process of investigating their function in the context of diseases.

So, you mean the gene expression picked from this study can be implemented to tailor adjuvant therapy among common cancers?

Mutations in mitochondrial DNA (mtDNA) can cause a range of incurable and life-limiting metabolic diseases in humans. Our current study has identified crucial disease associated with genetic variants in the mitochondrial genomes of the Zoroastrian-Parsi community. Our study is a necessary first step to tailor therapeutic strategies that involve targeting validated mitochondrial biomarkers involved in diseases. Given the advent of technologies that enable precise genome editing like CRISPR, we believe our study will benchmark crucial mitochondrial disease-associated variants, classify its prevalence and risk outcomes to complement and tailor therapies that can correct genetic mutations, thus improving patient outcomes in the case of complex genetic diseases like cancers.

How much of your study will pave the path to an era of personalised medicine?

It may be fortuitous that our current study is published on the heels of another study published describing important milestone in editing mitochondrial genomes. Mok, BY et al (Nature, July 2020) has demonstrated the ability to enable precise editing of mtDNA. Our study and its future outcomes will provide a database of mitochondrial variants associated with various conditions to further enhance the possibility of precisely editing the inheritable mutations in mitochondrial genomes, moving the needle towards personalised medicines.

Are there any indicators that may raise caution?

Indeed, any disease associations in a dwindling population is a cause for concern. We show an increased association of variants with conditions like Parkinsons disease, prostate, colon and ovarian cancers, rare diseases resulting in an inherited visual disability like LHON, hearing disability, muscular dystrophy like diseases and infertility. Understanding the molecular mechanisms of these variants resulting in clinical manifestations is extremely important in framing healthcare policies that include precise diagnostic platforms for early disease diagnosis and therapy, steps necessary to arrest the declining numbers in communities like the Zoroastrian-Parsis and other close-knit communities across the world.

What are your predictions for the next five years in cancer biomarker development and validation?

In the next five years, understanding of most cancers would be linked to population genetics and would be individualised into specific groups for treatment. Specific targeted drugs linked to a subset of biomarkers found in each individual patient leading to precision individualised therapies would be the order of the day.

Do you think that there is a need for a cross-disciplinary integration of scientific and clinical expertise for research especially in the field of cancer?

Cross-disciplinary research, especially in cancer, is increasingly relevant and important to reducing that gap in what is identified as best practice and what happens in clinical care. Narrowing this knowledgepractice gap continues to be a slow, complex, and poorly understood process, particularly for research that encompasses the notion of transdisciplinarity, as in the case of complex diseases like cancers. The assimilation of diverse perspectives, research approaches, and types of knowledge is important in helping research teams tackle real-world patient care issues, create more practice-based evidence, and translate the results to clinical and community care settings.

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How genetic studies will become the holy grail to find cancer biomarkers in future - Express Healthcare

Demand for Functionalized Polyolefins to Scale New Heights as Market Players Focus on Innovations 2019 2029 – Bulletin Line

Evaluation of the Global Functionalized Polyolefins Market

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A complete evaluation of the trends, market drivers, opportunities, and challenges faced by market players operating in the Functionalized Polyolefins market is provided in the report. Further, an overview and introduction of the Functionalized Polyolefins market is included to ensure that the readers have a seamless experience while going through the contents of the report.

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The competitive outlook assessment provides an in-depth understanding related to the business proceeding of top-tier market players in the global Functionalized Polyolefins market. The product portfolio, sales strategy, marketing & promotional strategy, and sales footprint of each market player is scrutinized thoroughly in the report. Some of the leading players evaluated in the report include:

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Demand for Functionalized Polyolefins to Scale New Heights as Market Players Focus on Innovations 2019 2029 - Bulletin Line

Researchers Discover Two Paths of Aging and New Insights on Promoting Healthspan – UC San Diego Health

Yeast cells with the same DNA under the same environment show different structures of mitochondria (green) and the nucleolus (red), which may underlie the causes of different aging paths. Single and double arrowheads point to two cells with distinct mitochondrial and nucleolar morphologies.

Molecular biologists and bioengineers at the University of California San Diego have unraveled key mechanisms behind the mysteries of aging. They isolated two distinct paths that cells travel during aging and engineered a new way to genetically program these processes to extend lifespan.

The research is described July 17 in the journal Science.

Our lifespans as humans are determined by the aging of our individual cells. To understand whether different cells age at the same rate and by the same cause, the researchers studied aging in the budding yeast Saccharomyces cerevisiae, a tractable model for investigating mechanisms of aging, including the aging paths of skin and stem cells.

The scientists discovered that cells of the same genetic material and within the same environment can age in strikingly distinct ways, their fates unfolding through different molecular and cellular trajectories. Using microfluidics, computer modeling and other techniques, they found that about half of the cells age through a gradual decline in the stability of the nucleolus, a region of nuclear DNA where key components of protein-producing factories are synthesized. In contrast, the other half age due to dysfunction of their mitochondria, the energy production units of cells.

The cells embark upon either the nucleolar or mitochondrial path early in life, and follow this aging route throughout their entire lifespan through decline and death. At the heart of the controls the researchers found a master circuit that guides these aging processes.

To understand how cells make these decisions, we identified the molecular processes underlying each aging route and the connections among them, revealing a molecular circuit that controls cell aging, analogous to electric circuits that control home appliances, said Nan Hao, senior author of the study and an associate professor in the Section of Molecular Biology, Division of Biological Sciences.

Having developed a new model of the aging landscape, Hao and his coauthors found they could manipulate and ultimately optimize the aging process. Computer simulations helped the researchers reprogram the master molecular circuit by modifying its DNA, allowing them to genetically create a novel aging route that features a dramatically extended lifespan.

UC San Diego biologists and bioengineers identified a master aging circuit that opens the door to genetically engineered prolonged life. Erik Jepsen/UC San Diego Publications

Our study raises the possibility of rationally designing gene or chemical-based therapies to reprogram how human cells age, with a goal of effectively delaying human aging and extending human healthspan, said Hao.

The researchers will now test their new model in more complex cells and organisms and eventually in human cells to seek similar aging routes. They also plan to test chemical techniques and evaluate how combinations of therapeutics and drug cocktails might guide pathways to longevity.

Much of the work featured in this paper benefits from a strong interdisciplinary team that was assembled, said Biological Sciences Professor of Molecular Biology Lorraine Pillus, one of the studys coauthors. One great aspect of the team is that we not only do the modeling but we then do the experimentation to determine whether the model is correct or not. These iterative processes are critical for the work that we are doing.

The research team included Yang Li (postdoctoral scholar, Biological Sciences), Yanfei Jiang (postdoctoral scholar, Biological Sciences), Julie Paxman (graduate student, Biological Sciences), Richard OLaughlin (former bioengineering graduate student, Jacobs School of Engineering), Stephen Klepin (laboratory assistant, Biological Sciences), Yuelian Zhu (visiting scholar), Lorraine Pillus (professor, Biological Sciences and Moores Cancer Center), Lev Tsimring (research scientist, BioCircuits Institute), Jeff Hasty (professor, Biological Sciences, Jacobs School of Engineering and BioCircuits Institute) and Nan Hao (associate professor, Biological Sciences and BioCircuits Institute).

The National Institutes of HealthNational Institute on Aging (AG056440) and National Science Foundation Molecular and Cellular Biosciences (1616127 and 1716841) supported the research. Julie Paxman was supported by UC San Diegos Cellular and Molecular Genetics training program, (5T32GM007240).

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Researchers Discover Two Paths of Aging and New Insights on Promoting Healthspan - UC San Diego Health

Matthew in the Middle: Mask it or casket – Eureka Times-Standard

The whole world is laughing at us. They cant understand why wearing a mask in public has become a political culture issue and not a medical necessity. It could be the fact that many otherwise intelligent Americans have been indoctrinated by Faux News and right-wing radio to only believe what they tell them and to distrust all other Main Stream Media, including science and health experts. So now, many people equate wearing a mask as anti-Trump and not wearing a mask as being pro-Trump instead of caring about the health and well-being of our fellow citizens.

This has brought out Karens, lots of angry Karens. We saw Target Karen (AKA Melissa Rein Lively of Scottsdale, Arizona) who actually filmed herself destroying a mask display: Im not playing any more fing games. This is over. This is over. This is over, she said again and again as she threw all the masks on the ground before being approached by stunned Target store employees. Why cant I do this? Because Im a blonde white woman? Im wearing a $40,000 Rolex and I dont have the right to do this? Then we saw Costco Karen, a 77-year old woman who wouldnt wear her mask as she said, I am a United States citizen. I have Constitutional rights, before sitting down in protest on the Costco cement floor like a 3-year old having a temper tantrum.

We witnessed Trader Joes Karen (AKA Sandrella Zadikian) losing it while being kicked out of the North Hollywood store during the grand opening for not wearing a mask. Youre fing pigs. Youre all fing Democratic pigs. All of you. That man is harassing me for not wearing a mask. I have a breathing problem. Sure didnt seem like she had any breathing problems when Karen was screaming at everyone. Then there was Home Depot Karen (AKA Teri Hill) who said while shopping maskless, Yes, I am entitled. Im white. Im a woman I believe in white power.

Now we have Starbucks Karen (AKA Amber Lynn Gilles) who posted a pic of barista Lenin Gutierrez on Facebook after she was kicked out of Starbucks for not wearing a mask. Someone started a GoFundMe for tip money for Gutierrez and raised over $100,000. Now Gilles claims she was discriminated against and wants half of that money.

My personal favorite was during public comments of the Ventura County Board of Supervisors meeting where Deborah Baber wearing her Trump 2020 T-shirt, red MAGA cap and holding up a Trump 2020 sign said. I protest face coverings I used to be free. I am not a terrorist. I am not antifa. I am not a sex slave who wears masks. I am not into sadomasochism and bondage, equating wearing a face mask to sex hoods. I am a proud Trump Republican yearning to be free again. Did someone kidnap this woman, transport her across an ocean and put her in chains to be sold as a slave that I missed? Scott Phillips, a Scottsdale, Arizona city councilmember said during a mask protest, I cant breathe. I cant breathe. I cant breathe, while taking off his mask. You can search all these on Google or YouTube and laugh for yourself. What do all these people have in common? 99.9% are Republican, white and ignorant.

Communicable diseases have been with us throughout history. Weve survived malaria, polio, tuberculosis, leprosy, smallpox and influenza. Pandemics happen every so often. 102 years ago the Spanish flu (which didnt start in Spain) ravaged the world. Some idiot posted on Twitter, There was no vaccine for the Spanish flu! Yes, thats correct. It burned out after killing an estimated 50 million people worldwide. We will defeat COVID-19 if we all work together by avoiding crowds, wearing masks in public, social distancing at least six feet and washing our hands often.

If you choose to not wear a mask, then you also have to choose to get sick and die at your home and not clog up our hospitals.

Matthew Owen resides in Eureka, and believes the First Amendment allows for free speech, even when married to a Humboldt County supervisor.

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Matthew in the Middle: Mask it or casket - Eureka Times-Standard

Nanomedicine Market 2020 Industry Share, Size, Consumption, Growth, Top Manufacturers, Type and Forecast to 2028 Bulletin Line – Bulletin Line

Most recent report on the global Nanomedicine market

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market dynamics section of this report analyzes the impact of drivers and restraints on the global nanomedicine market. The impact of these drivers and restraints on the global nanomedicine market provides a view on the market growth during the course of the forecast period. Increasing research activities to improve the drug efficacy coupled with increasing government support are considered to be some of the major driving factors in this report. Moreover, few significant opportunities for the existing and new market players are detailed in this report.

Porters five forces analysis provides insights on the intensity of competition which can aid in decision making for investments in the global nanomedicine market. The market attractiveness section of this report provides a graphical representation for attractiveness of the nanomedicine market in four major regions North America, Europe, Asia-Pacific and Rest of the World, based on the market size, growth rate and industrial environment in respective regions, in 2012.

The global nanomedicine market is segmented on the basis of application and geography and the market size for each of these segments, in terms of USD billion, is provided in this report for the period 2011 2019. Market forecast for this applications and geographies is provided for the period 2013 2019, considering 2012 as the base year.

Based on the type of applications, the global nanomedicine market is segmented into neurological, cardiovascular, oncology, anti-inflammatory, anti-infective and other applications. Other applications include dental, hematology, orthopedic, kidney diseases, ophthalmology, and other therapeutic and diagnostic applications of nanomedicines. Nanoparticle based medications are available globally, which are aimed at providing higher bioavilability and hence improving the efficacy of drug. There have been increasing research activities in the nanomedicine filed for neurology, cardiovascular and oncology applications to overcome the barriers in efficient drug delivery to the target site. Moreover, the global nanomedicine market is also estimated and analyzed on the basis of geographic regions such as North America, Europe, Asia-Pacific and Rest of the World. This section describes the nanomedicine support activities and products in respective regions, thus determining the market dynamics in these regions.

The report also provides a few recommendations for the exisitng as well as new players to increase their market share in the global nanomedicine market. Some of the key players of this market include GE Healthcare, Mallinckrodt plc, Nanosphere Inc., Pfizer Inc., Merck & Co Inc., Celgene Corporation, CombiMatrix Corporation, Abbott Laboratories and others. The role of these market players in the global nanomedicine market is analyzed by profiling them on the basis of attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments.

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Nanomedicine Market 2020 Industry Share, Size, Consumption, Growth, Top Manufacturers, Type and Forecast to 2028 Bulletin Line - Bulletin Line

NASA confirms plans for Crew Dragon splashdown Aug. 2, weather permitting – Spaceflight Now

In this image taken July 1, a spacewalking astronaut snapped a view of the Crew Dragon spacecraft (at right) docked with the International Space Station. Japans HTV cargo ship, at bottom in gold, is also seen attached to the space station. Credit: NASA

Assuming good weather and a smooth final few weeks on the International Space Station, astronauts Doug Hurley and Bob Behnken are scheduled to undock from the orbiting research outpost Aug. 1 and return to Earth the next day to wrap up a 64-day test flight of SpaceXs Crew Dragon spaceship.

NASA Administrator Jim Bridenstine confirmed the target dates for the Crew Dragons undocking and splashdown in a tweet Friday.

A few hours after departing the space station, the Crew Dragon will fire its Draco thrusters for a braking burn and re-enter the atmosphere, targeting a parachute-assisted splashdown at sea.

Splashdown is targeted for Aug. 2, he tweeted. Weather will drive the actual date. Stay tuned.

NASA and SpaceX are assessing return zones in the Atlantic Ocean and the Gulf of Mexico.

Officials originally selected landing sites in the Atlantic east of Cape Canaveral and Jacksonville, and a location in the Gulf of Mexico south of Pensacola, Florida. Last month, NASA said officials were evaluating additional candidate locations for the Crew Dragons splashdown off Daytona Beach, Tampa, Tallahassee and Panama City.

The additional options would give mission managers more flexibility in deciding when to approve the Crew Dragons undocking and re-entry.

The final selection of a landing site will hinge on weather and sea states. Assessments of climatology suggest conditions in the Gulf of Mexico have a higher likelihood of being favorable for splashdown in early August, sources said.

Hurley and Behnken will be the first NASA astronauts to return to Earth for a water landing since Tom Stafford, Deke Slayton and Vance Brand splashed down July 24, 1975, in an Apollo command module to end the Apollo-Soyuz mission, which included the first docking between U.S. and Russian spacecraft in orbit.

Probably the biggest area of concern is just how long its been since humans have done this on the U.S. side splashing down in the water and then being recovered, Behnken said from the space station in a recent interview with the Washington Post.

SpaceX has practiced recovering capsules at sea with cargo missions returning from the space station, an unpiloted Crew Dragon test flight last year, and a series of training sessions and rehearsals.

Theyve done that many times at this point, and theyve recovered those capsules pretty successfully and managed to get the timeline relatively short so that we expect to be back on the ship within an hour of splashdown, Behnken said.

The crew is expected to remain inside the Dragon until the spacecraft is hoisted onto the deck of SpaceXs recovery ship.

The Crew Dragon spacecraft launched with Hurley and Behnken on top of a Falcon 9 rocket May 30 from NASAs Kennedy Space Center in Florida. It was the first launch of astronauts into orbit from U.S. soil since the last space shuttle launch July 8, 2011.

The crew capsule autonomously docked with the International Space Station on May 31, allowing Hurley and Behnken to join space station commander Chris Cassidy and Russian cosmonauts Anatoly Ivanishin and Ivan Vagner.

The primary goal of the Crew Dragons first mission with astronauts named Demo-2, or DM-2 is to test the SpaceX-built capsules performance before it begins regular crew rotation flights to the space station later this year. SpaceX successfully flew an unpiloted Crew Dragon to and from the space station in 2019 before NASA approved the capsule to carry astronauts.

Hurley and Behnken have also assisted the space stations long-duration crew with experiments, maintenance and other tasks. The Demo-2 mission was originally planned to last no more than a couple of weeks, but NASA announced earlier this year the test flight would be extended to expand the size of the crew on the space station.

At the time, Cassidy was the final U.S. astronaut NASA had booked to fly on Russias Soyuz spacecraft, which has been the sole vehicle to carry crews to and from the space station since the end of the space shuttle program nearly a decade ago. That meant Cassidy would have been the only U.S. astronaut on the station for most of the time from April through October, limiting opportunities for research and spacewalks needed to upgrade and maintain the orbiting complex.

With the extended Demo-2 mission, Behnken has joined Cassidy on three spacewalks since June 26 to finish replacing batteries on the space stations solar power truss. One more spacewalk by Behnken and Cassidy is scheduled for Tuesday, July 21.

NASA says the Crew Dragon has performed well since its launch. While docked at the space station, the capsule has been put into hibernation and awakened several times to check its availability to serve as a lifeboat for the crew if they had to evacuate the orbiting research lab in an emergency.

Ground teams have also monitored the performance of the Crew Dragons body-mounted solar arrays, which can degrade over time due to the harsh environment in low Earth orbit. So far, the power-generating arrays have performed better than predicted.

Last week, four of the space station crew members boarded the Crew Dragon to assess the ships ability to accommodate a four-person crew in orbit, particularly when astronauts will be required to sleep on the vehicle during the transit to and from the space station.

If the Demo-2 mission returns to Earth in early August, SpaceX and NASA will press ahead with preparations for the first operational Crew Dragon mission. That flight, designated Crew-1, is currently scheduled to launch from the Kennedy Space Center in mid-to-late September.

Steve Stich, NASAs commercial crew program manager, said last month that engineers will need around six weeks evaluate data from the Crew Dragon test flight before formally certifying the capsule as ready for operational missions.

The brand new Falcon 9 first stage booster for the Crew-1 mission arrived Tuesday at Cape Canaveral for launch preparations. The Crew Dragon spacecraft for the Crew-1 mission will arrive in the coming weeks.

NASA astronauts Mike Hopkins, Victor Glover, Shannon Walker, and Japanese astronaut Soichi Noguchi are training for the Crew-1 mission. Noguchi, a veteran of two previous space missions, will become the first astronaut to launch on the space shuttle, Russias Soyuz rocket, and SpaceXs Falcon 9.

NASA has ordered six crew rotation flights on the Crew Dragon spacecraft through 2024, each carrying four astronauts to and from the space station on expeditions lasting as long as 210 days. SpaceX also has agreements with Axiom Space and Space Adventures, two commercial space companies, to fly private citizens into orbit on shorter-duration Crew Dragon missions beginning as soon as late 2021.

SpaceX developed the Crew Dragon under contract to NASA, but the company is free to use the spacecraft for commercial flights without NASA involvement.

NASA has a similar contract with Boeing for development of the Starliner crew capsule, which has yet to fly with astronauts. An unpiloted Starliner test flight was cut short before docking with the space station in December, and Boeing plans to fly a second demonstration mission later this year before a test flight with a crew on-board in early 2021.

There are several modifications to the capsule SpaceX is building for the Crew-1 mission, although major components such as the capsules life support system and guidance, navigation and control systems are largely unchanged from the Demo-2 configuration.

The Crew-1 vehicle can land in a little bit higher wind state, Stich said in a press briefing May 31. SpaceX has changed some of the outer composite panels to make that a little stronger.

It also has the capability not only dock to the forward port of the space station, but it can go to the zenith (space-facing) port as well, so it has that capability, and it has a couple other features, Stich said.

NASA and SpaceX have not released the official wind and sea state constraints officials will use to determine the final schedule and location for the Demo-2 splashdown.

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NASA confirms plans for Crew Dragon splashdown Aug. 2, weather permitting - Spaceflight Now

Join the National Space Society for ‘A Day in Space,’ a celebration of spaceflight, this week – Space.com

On July 16, 2020, a unique online presentation from the National Space Society will bring the solar system to your doorstep. "A Day in Space" is a day-long virtual forum that promises some truly unique spaceflight and exploration experiences.

In an exclusive interview with NSS President and television personality, Geoffrey Notkin, Apollo 11 astronaut Buzz Aldrin will take you back into the heady years of the Space Race and plunge you into the future of the exploration of our solar system.

Planetary scientist Alan Stern will take you on a journey to Pluto and beyond to tiny Arrokoth (formerly known as Ultima Thule), as he recalls how the hard-fought New Horizons probe ventured to the edge of the planetary system and unveiled its secrets. NASA engineer and NSS Senior Operating Officer Bruce Pittman tells us about the merging of Wernher von Braun and Gerard O'Neill's visions to form the National Space Society.

Billionaire NewSpace financier Steve Jurvetson tells the thrilling tale of investing in SpaceX in some of their darkest moments, supporting disruptive innovation with Planet Labs, and the future of orbital space tourism and investing in the space business.

Jet Propulsion Laboratory chief engineer Rob Manning and space author Rod Pyle square off for a smackdown over the character of Mars a lovely place in the eyes of Ray Bradbury and Edgar Rice Burroughs until NASA came along with Mariner 4 in 1965 and told us the cold, dry truth about the planet. Manning explains why thats even better than what came before.

"A Day in Space" is co-hosted by Notkin, who is also the president of the National Space Society, and Dr. Sian Proctor, college professor, geoscientist and NASA astronaut finalist.

"A Day in Space was created to fill the gap left by the postponement of the National Space Society's 2020 International Space Development Conference due to COVID-19 this year," said Pyle, who is also the editor-in-chief of the society's quarterly print magazine, Ad Astra, "but it quickly took on a life of its own, bringing together some of the best and brightest in space exploration and settlement to tell their exciting stories first-hand. Its been an incredible honor to work with these folks."

Additional presentations include Dr. Sara Seager on the latest from the search for exoplanets; a discussion of inclusiveness and diversity in the space industry with the Chairman of the NSS Board of Governors, Karlton Johnson; and a reprise of a very special Apollo 50th anniversary event with Apollo astronauts Al Worden, Fred Haise, Walt Cunningham and Flight Director Gerry Griffin (this was one of Worden's final appearances before his passing last March).

Dr. Anthony Paustian, the NSS's Director of Communication and Branding, leveraged his extensive connections from his own yearly conference, CiLIVE, in Des Moines, Iowa, to bring "A Day in Space" to life.

"I've had the honor of presenting some of the most creative and dynamic people in space exploration, including many Apollo astronauts, to the public. 'A Day in Space' is the perfect way to wrap-up the 50th anniversary of the first landings on the moon. We know youll enjoy these presentations they are truly one-of-a-kind."

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Join the National Space Society for 'A Day in Space,' a celebration of spaceflight, this week - Space.com