An ONeal Comprehensive Cancer Center scientist presents at a major oncology meeting about a novel artificial intelligence software tool to assist evaluating tumor response in advanced cancers.
An ONeal Comprehensive Cancer Center scientist presents at a major oncology meeting about a novel artificial intelligence software tool to assist evaluating tumor response in advanced cancers.In a multi-institution study presented this week at the annual meeting of the American Society of Clinical Oncology, researchers from the ONeal Comprehensive Cancer Center at the University of Alabama at Birmingham compared the current practice of evaluating tumor response in advanced cancer with an artificial intelligence software tool designed to assist radiologists.
It turns out that human-guided AI is more accurate, more reproducible and faster, said Andrew Smith, M.D., Ph.D., associate professor, vice chair of Clinical Research and co-director of AI in the UAB Department of Radiology, and director of the Tumor Metrics Lab, a component of the ONeal Cancer Centers Human Imaging shared resource, who presented the findings today at ASCO.
The Tumor Metrics Lab conducts image interpretation for all cancer patients on clinical trials in the ONeal Cancer Center who have tumor imaging to determine their response to treatment. The lab does more than 1,000 tumor metric reads per year.
Doctors track the progress of tumors using computed tomography scans. Radiologists measure the tumors manually on digital images of those scans and usually dictate their findings into text-based reports. But the group of researchers behind the new study hypothesized that this traditional system could be improved with some assistance from artificial intelligence. They used AI Mass, a cancer-specific implementation of the medical AI software platform AI Metrics, trained with more than 15,000 expert-labeled images.
AI Mass uses AI to, one, measure tumors after a single mouse click; two, automatically label the anatomic location of tumors; and three, track tumors over time, Smith said. AI Metrics is a product of a startup company of the same name, with Smith as CEO, that was spun off from UAB in 2019 and is now raising a seed round of capital.
In the study presented at ASCO by Smith, body CT images from 120 consecutive patients with advanced cancer were independently evaluated by 24 radiologists. The patients all had multiple serial imaging exams and had been treated with systemic therapy. Each radiologist categorized treatment responses and dictated text-based reports. Meanwhile, the AI-assisted software automatically calculated percent changes in tumor burden and categorized treatment response using standardized methods commonly found in clinical trials. A team of researchers looked for major errors such as incorrect measurements, erroneous language in reports or misidentifying the tumor location time spent in image interpretation and inter-reader agreement about the final tumor response. Twenty oncologic providers then evaluated the accuracy of the manually dictated text reports versus AI-assisted reports that included a graph, table and key images.
The AI-assisted approach increased accuracy by 25 percent, reduced major errors by 99 percent, was nearly two times faster than current practice methods, and improved inter-reader agreement by 45 percent, Smith said. The only error by the AI-assisted software was a freeform text note that we could not interpret, he noted. All of the tumor measurements, percent changes, etc., were correct. Smith, who is owner of AI Metrics as well as its CEO, did not directly participate in data gathering, have access to study data or conduct any of the statistical analysis.
Andrew Smith, M.D., Ph.D.It is gratifying to see such a practical application of artificial intelligence, said Cheri Canon, M.D., professor, chair and Witten-Stanley Endowed Chair of the Department of Radiology. Seldom do we hear of such overwhelmingly positive results from a study: 99 percent reduction in major errors. The impact this will have on patients, specifically cancer patients, will be far-reaching.
The work has other benefits, Canon noted. These include improved workflow for the radiologists, who are now more than ever burdened with complex imaging studies and increased incidence of burnout, and for our clinical colleagues, a clear and concise longitudinal report. This is a monumental improvement to the current standard of care and will in fact set a new standard.
The project involves collaborators from 21 institutions and three small businesses, including AI Metrics. The AI behind the software was trained using carefully annotated images from UAB and the National Institutes of Health by a team of UAB clinical research scientists, Smith says.
We drew freeform shapes around the edge of each tumor to train the AI to do the same, he explained. We also labelled the anatomic location of all kinds of tumors located across different parts of the body. We were able to train the AI to provide an anatomic location of the tumor. That had never been done before.
In practice, the user guides the AI, but the AI does the measuring and labeling, Smith said. We can extract the measurements in a digital form. Because the data is digital, we can generate a graph or table, and we can even save key images of all image findings. The AI-assisted reports are a major leap beyond a text-based report.
Importantly, radiologists work with the AI throughout the process, Smith says.
Lets say there is a tumor in the liver that needs to be followed over time, he said.In our AI Metrics software,theuser simply clicks on a lesion and a first AI algorithm measures it.The user can change it within two seconds if something is wrong. As you can imagine, the AI is more reliable than having different radiologists do this manually.This is what we call transparent AI, where the user both directsthe AI and can check it. Then a second AI algorithm provides the anatomic location. The user can easilycheck andcorrect this as well within about two seconds.
As part of the study, radiologists and 20 oncologic providers were asked to rate the experience of using the AI-assisted software and the value of the AI-assisted reports.
The AI-assisted software was preferred by 96 percent of radiologists, and the AI-assisted reports were preferred by 100 percent of oncologic providers, Smith said. We have established a new standard of care with AI. I think that having this software could save lives, though we dont yet have that kind of data.
Smith says the team is not done.
Since the study, we re-trained the AI on 55,000 tumors, and we hope to get closer to 100,000 in the coming months, he said. That is more tumors than an average radiologist measures in a lifetime. This is how we leverage the power of AI. The researchers are now writing an NIH grant to take their work into cancer screening and early cancer detection and management, Smith says. Most cancer therapies apply to only a few cancers or even a subtype of a single cancer. This technology applies to all solid cancers imaged on CT and MRI. We can apply this technology to many other stages of cancer.
Read an abstract of the study, Multi-institutional comparative effectiveness of advanced cancer longitudinal imaging response evaluation methods: Current practice versus artificial intelligence-assisted, on ASCOs website here.
- AI in the courts - The Indian Express - July 12th, 2021
- Infrared cameras and artificial intelligence provide insight into boiling - MIT News - July 12th, 2021
- COVID: Artificial intelligence in the pandemic - DW (English) - July 12th, 2021
- The smart role of Artificial Intelligence in todays world - BL on Campus - July 12th, 2021
- Which companies are leading the way for artificial intelligence in the aerospace, defence & security sector? Companies leading the way for... - July 12th, 2021
- Navigating the Intersections of Data, Artificial Intelligence, and Privacy - JD Supra - July 12th, 2021
- Companies leading the way for artificial intelligence in the power sector - Power Technology - July 12th, 2021
- Military researchers ask for artificial intelligence (AI) and machine learning able to share experiences - Military & Aerospace Electronics - July 12th, 2021
- The Evolution of the Judiciary in the Age of Technology | Artificial Intelligence and the Delivery of Justice - Lexology - July 12th, 2021
- Content management and Artificial Intelligence the future of ContentOps - ITProPortal - July 12th, 2021
- How artificial intelligence is propelling the energy transition forward - Innovation Origins - July 12th, 2021
- Astronomers use artificial intelligence to reveal the true shape of universe - WION - July 12th, 2021
- A History of Regular Expressions and Artificial Intelligence - kottke.org - kottke.org - July 12th, 2021
- Experimenting thoughtfully with artificial intelligence - Reuters - June 15th, 2021
- VisionQuest Uses Artificial Intelligence to Screen 40000 Patients for Diabetic Retinopathy - Business Wire - June 15th, 2021
- Artificial Intelligence for Rapid Exclusion of COVID-19 Infection - SciTechDaily - June 15th, 2021
- Researchers ask industry for military technologies in artificial intelligence (AI) and unmanned aircraft - Military & Aerospace Electronics - June 15th, 2021
- 5 Uses of Artificial Intelligence to Improve Customer Experience Measurement - Small Business Trends - June 15th, 2021
- Artificial intelligence and the McData-fueled future of capitalism - The Next Web - June 15th, 2021
- 5 Types of Artificial Intelligence that will Shape 2021 and Beyond - Analytics Insight - June 15th, 2021
- How Artificial Intelligence will Transform Businesses in 2021? - Analytics Insight - June 15th, 2021
- Use of Artificial Intelligence in the Research of Quantum Mechanics - Analytics Insight - June 15th, 2021
- Global Wearable Medical Devices Markets Report 2021: Integrating Artificial Intelligence in the Wearable Medical Devices is Gaining Traction -... - June 15th, 2021
- Your Future May Lie With an Artificial Intelligence Certificate - The Future of Things - June 15th, 2021
- White House partners with NSF to stand up National AI Research Resource Task Force - Federal News Network - June 15th, 2021
- RGS welcomes Artificial Intelligence Innovator to training event - Attain News - June 15th, 2021
- An artificial-intelligence powered ETF has smashed the S&P 500 in the last month without any meme stocks - Markets Insider - June 15th, 2021
- How Artificial Intelligence Is Changing the Future of Air Transportation - GW Today - June 15th, 2021
- Can We Learn Sperm Whale Language? Researchers Are Using Artificial Intelligence to Find Out - TheInertia.com - June 15th, 2021
- Artificial Intelligence in the Pharmaceutical market worth US$27156.1 Million in 2031. Visiongain Research Inc. - GlobeNewswire - June 15th, 2021
- Artificial Intelligence And The End Of Work - Forbes - February 17th, 2021
- DoDs AI center striving to be connective tissue across all projects - Federal News Network - February 17th, 2021
- How Artificial Intelligence is Improving the Online Sports Betting Experience - MWWire - February 17th, 2021
- Chess and Artificial Intelligence (2) - Chessbase News - February 17th, 2021
- Calastone implements Opsmatix Artificial Intelligence solution Improving client handling and efficiency within client operations - PRNewswire - February 17th, 2021
- Global Automotive Artificial Intelligence Market (2020 to 2026) - by Component, Technology, Process, Application, Vehicle Type, Demand Category,... - February 17th, 2021
- Liverpool scientists deploy Artificial Intelligence to develop model that predicts the next pandemic - Times Now - February 17th, 2021
- Why Artificial Intelligence May Not Offer The Business Value You Think - CMSWire - February 17th, 2021
- Needed: People To Put The Intelligence In Artificial Intelligence - Forbes - February 17th, 2021
- From vision to reality: the rise of Artificial Intelligence in the healthcare sector - Health Europa - February 17th, 2021
- Chess and Artificial Intelligence (1) - Chessbase News - February 17th, 2021
- Artificial intelligence helps automation, but can't tell you where to put your money, Indexa CEO says - Business Insider - February 17th, 2021
- Excerpt: 'Artificial Intelligence and the Future of Power' by Rajiv Malhotra - Times of India - February 17th, 2021
- BYU lab works to improve artificial intelligence communication - The Daily Universe - Universe.byu.edu - February 17th, 2021
- Artificial intelligence used to monitor patients with chronic diseases and COVID-19 - University of Virginia The Cavalier Daily - February 17th, 2021
- Elon Musk Talks Auto Safety and Regulation of Artificial Intelligence with Joe Rogan - Corporate Crime Reporter - February 17th, 2021
- Artificial Intelligence in Medicine Market is expected to rise at a remarkable CAGR during the Forecast Period 2020-2026 KSU | The Sentinel Newspaper... - February 17th, 2021
- AI Definition & Meaning | What is Artificial Intelligence? - February 7th, 2021
- Artificial Intelligence and Sustainable Development Goals - Analytics Insight - February 7th, 2021
- Artificial Intelligence can predict whether you will die from COVID-19 - Free Press Journal - February 7th, 2021
- Beyond the Unknown: Applications of Artificial intelligence In Space - Analytics Insight - February 7th, 2021
- Two UWF teams place in top 5 in national artificial intelligence competition - University of West Florida Newsroom - UWF Newsroom - February 7th, 2021
- Bingo and AI: The changing relation between entertainment and artificial intelligence - Analytics Insight - February 7th, 2021
- Off The Menu: Artificial intelligence lends hand in recipe development - MassLive.com - February 6th, 2021
- Artificial intelligence must not be allowed to replace the imperfection of human empathy - The Conversation UK - February 6th, 2021
- Artificial intelligence and the Gamestonk blowback - The Next Web - February 6th, 2021
- Artificial Intelligence in Policing Is the Focus of Encode Justice - Teen Vogue - February 6th, 2021
- 'Artificial Intelligence' Integrated PET-CT launched at Yashoda Hospitals, Hyderabad on the occasion of World Cancer Day 2021 - PR Newswire India - February 6th, 2021
- SLAS Technology Special Collection on Artificial Intelligence in Process Automation Available Now - Newswise - February 6th, 2021
- Artificial Intelligence Will Change The Way We Work Once We Get Back To The Office - Forbes - February 6th, 2021
- Chemistry and computer science join forces to apply artificial intelligence to chemical reactions - Princeton University - February 6th, 2021
- How to Build a Modern Workplace with Artificial Intelligence and Internet of Things - BBN Times - February 6th, 2021
- Morality Poses the Biggest Risk to Military Integration of Artificial Intelligence - The National Interest - February 6th, 2021
- Canon Medical expands reach of its MRI artificial intelligence programs - FierceBiotech - February 6th, 2021
- Harnessing the Power of Artificial Intelligence with High-Performance Computing: Dell Technologies - CRN - India - CRN.in - February 6th, 2021
- AI-Powered Cooperation Will Transform US Military Operations Homeland Security Today - HSToday - February 6th, 2021
- Skinopathy Files Provisional Patent for Artificial Intelligence and Augmented Reality Powered Technology that will Guide Skin Cancer Surgeries - Yahoo... - February 6th, 2021
- How Artificial intelligence is Transforming the Apparel Industry - BBN Times - February 6th, 2021
- How Airbus And Boeing Are Using Artificial Intelligence To Advance Autonomous Flight - Simple Flying - February 6th, 2021
- Artificial Intelligence Robots Market to Witness Huge Growth by Top Key Players | Welltok, Inc., Intel Corporation, Nvidia Corporation And More KSU |... - February 6th, 2021
- A crewless boat is recreating the Mayflower's 400-year-old journey, with the help of artificial intelligence - CBS News - December 26th, 2020
- Artificial Intelligence (AI): Is It All Just Costly Hype? - Dice Insights - December 26th, 2020
- 7 Types of Artificial Intelligence: Propelling the Technology Development - Analytics Insight - December 26th, 2020
- Artificial intelligence will go mainstream in 2021 The Manila Times - The Manila Times - December 26th, 2020
- Top 7 Amazing Artificial Intelligence Applications that Are Unfamiliar - Analytics Insight - December 26th, 2020
- NASCAR Team up with the World Poker Tour while Artificial Intelligence Breaks New Barriers - HighstakesDB - December 26th, 2020
- Youve heard of Elf on the Shelf; in New Haven theres elf with artificial intelligence - New Haven Register - December 26th, 2020
- How is Artificial Intelligence Transforming the lives of People with Disabilities? - Analytics Insight - December 26th, 2020
- How Bad Is Your Spotify? There's Artificial Intelligence to Judge Your Taste - Distractify - December 26th, 2020
- Artificial intelligence measure included in must-pass government funding deal - Homeland Preparedness News - December 26th, 2020